ライフサイエンスコーパス: tumour cell line

1 ectopically in the 833K testicular germ cell tumour cell line.

2 in reaction (RT-PCR) in Ewing's sarcoma cell tumour cell lines.

3 y in glyoxalase 1-linked multidrug resistant tumour cell lines.

4 been identified as dysfunctional in numerous tumour cell lines.

5 as that influence the homing of a variety of tumour cell lines.

6 d was hypermethylated in primary tumours and tumour cell lines.

7 wnregulation of BLU transcript expression in tumour cell lines.

8 % neuroblastoma and 80% nasopharyngeal (NPC) tumour cell lines.

9 ession was downregulated in a subset of lung tumour cell lines.

10 NORE1B promoter was unmethylated in the same tumour cell lines.

11 nasopharynx, as well as in a subset of lung tumour cell lines.

12 ollection of 533 genetically annotated human tumour cell lines.

13 the well-defined 833K and GCT27 human testis tumour cell lines.

14 pendent growth of two out of four colorectal tumour cell lines.

15 o the genomic instability of some colorectal tumour cell lines.

16 this heterogeneity can differ between human tumour cell lines.

17 14(ARF) expression and p53 function in human tumour cell lines.

18 NA and the persyn gene in breast tumours and tumour cell lines.

19 og XRCC2 (342delT) found in an HRR-defective tumour cell line, 342delT was introduced into HRR profic

20 RASSF2 was frequently methylated in breast tumour cell lines (65%, 13/20) and in primary breast tum

21 hypermethylated in a majority of colorectal tumour cell lines (89%) and in primary colorectal tumour

22 We identified a tumour cell line, 97-7, expressing the most common FGFR3

23 In the present study, tumour cell lines: A549 (lung), HCT116 (colon) and MCF-7

24 DH LRES patterns are reflected in colorectal tumour cell lines; adenoma cell lines are not methylated

25 uld be switched back on in methylated breast tumour cell lines after treatment with 5'-aza-2'deoxycyt

26 F2A expression was reactivated in methylated tumour cell lines after treatment with 5-aza 2-deoxycyti

27 (RASSF1A) was absent in the majority of lung tumour cell lines analysed.

28 1) fusion were identified in 4 of 43 bladder tumour cell lines and 2 of 32 selected tissue samples in

29 essed in some but not all breast and ovarian tumour cell lines and also in a glioma cell line.

30 analysed BLU promoter methylation status in tumour cell lines and detected promoter region hypermeth

31 n the majority of primary lung tumours, lung tumour cell lines and in a variable percentage of breast

32 ation has been previously detected in breast tumour cell lines and in colon tumours; here, we report

33 xpression of erbB-4 mRNA in a range of human tumour cell lines and in normal and malignant breast tis

34 reduces MST2 levels, in addition colorectal tumour cell lines and primary tumours with low RASSF2 le

35 the essential oil displayed cytotoxicity on tumour cell lines and showed IC50 values ranging from 24

36 cyte polarity; H.sapiens HEM45, expressed in tumour cell lines and uterus and regulated by oestrogen;

37 Natural killer (NK) cells attack many tumour cell lines, and are thought to have a critical ro

38 pression correlates with chemo-resistance of tumour cell lines, and reductions in Bcl-2 increase sens

39 Instead, MMR-defective tumour cell lines are also defective in homologous recom

40 Here we show that MMR-deficient tumour cell lines are highly sensitive to the toxic effe

41 45gamma gene was also found in the pituitary tumour cell line AtT20.

42 the antitumour potential was tested in human tumour cell lines (breast, lung, colon, cervical and hep

43 the antitumour potential was tested in human tumour cell lines (breast, lung, colon, cervical and hep

44 f breast carcinoma tissue samples and breast tumour cell lines, but not normal mammary tissue or beni

45 LM and CLW showed growth inhibition of human tumour cell lines by 0-46%.

46 d human NKG2D ligands are upregulated in non-tumour cell lines by genotoxic stress and stalled DNA re

47 Established cervical tumour cell lines carrying HPV were unable to communicat

48 the range of transcripts encoded in a breast tumour cell line, compared to normal breast, suggested t

49 mour viruses SV40 or adenovirus, or in human tumour cell lines, contained very low levels of or no de

50 h provides access to the European Searchable Tumour Cell-Line Database, a cell bank of immunologicall

51 h provides access to the European Searchable Tumour cell-line database, a cell bank of immunologicall

52 h provides access to the European Searchable Tumour Cell-Line Database, a cell bank of immunologicall

53 Thus, tumour cell lines derived using this methodology represe

54 Importantly, the 25 new ovarian tumour cell lines described here retain the genomic land

55 ents that exhibit cytotoxic activity against tumour cell lines due to their ability to inhibit topois

56 1) are also critical for survival of certain tumour cell lines during replication stress, making it a

57 A subset of tumour cell lines exhibit dependence on MCL1 expression

58 Conversely, in lung tumour cell lines expressing Kras(G12D) and lacking p53,

59 of DNA synthesis and Ras ADP-ribosylation in tumour cell lines expressing normal and mutant Ras revea

60 e screened conditioned media from a panel of tumour cell lines for their ability to induce suppressiv

61 NHEJ was found in established tumour cell lines from different originating tissues, th

62 Somatic mutation data from tumours and tumour cell lines have been mapped onto the crystal stru

63 ping homozygous deletions in lung and breast tumour-cell lines have defined a minimal critical 120 kb

64 l extracts exerted cytotoxicity against some tumour cell lines (HeLa, MCF7, HT-29), besides the promi

65 xpression of TRF1 in the telomerase-positive tumour-cell line HT1080 resulted in a gradual and progre

66 e cell model as well as in the human colonic tumour cell line, HT29, using whole-cell voltage clamp.

67 inhibitors of the proliferation of numerous tumour cell lines in culture and of murine syngeneic tum

68 also observed effective killing of lymphoid tumour cell lines in vitro following exposure to ALX, al

69 tected in mononuclear leukocytes in vivo and tumour cell lines in vitro.

70 as depletion of RBFOX2 in primary pancreatic tumour cell lines increased the metastatic potential of

71 nstitutively high levels in many tumours and tumour cell lines, indeed this phenomenon has been used

72 esent evidence that p53 protein stability in tumour cell lines is determined by association with the

73 er, HIV-1 restriction by human TRIM5alpha in tumour cell lines is minimal(21) and inhibition of such

74 ults show that a low XPA level in the testis tumour cell lines is sufficient to explain their poor ab

75 l DNA (mtDNA) were introduced into two human tumour cell lines lacking mtDNA.

76 The prostate tumour cell line LNCaP was transfected with this vector

77 e the fidelity of DSB repair in the prostate tumour cell line LNCaP, the bladder tumour cell line MGH

78 t the thymidine sensitivity of MMR-deficient tumour cell lines may be a consequence of defects in the

79 lation events in two triple- negative breast tumour cell lines, MFM223 and SUM52, that exhibit amplif

80 prostate tumour cell line LNCaP, the bladder tumour cell line MGH-U1 and a radiosensitive subclone S4

81 er region of DUTT1 gene in the HTB-19 breast tumour cell line (not expressing DUTT1) showed complete

82 ther murine tissues, as well as in six human tumour cell lines of epithelial origin, including two co

83 against Caco-2 and MCF-7 cancer cell lines (tumour cell lines of intestinal and mammary origin, resp

84 here that expression of mouse mutant p53 in tumour cell lines of this type results in high levels of

85 cells, indicating possible dependence of the tumour cell line on mutant FGFR3.

86 Currently available human tumour cell line panels consist of a small number of lin

87 A molecules of both glioblastoma tissues and tumour cell lines present bacteria-specific peptides.

88 ls using STC-1, a mouse intestinal endocrine tumour cell line, previously shown to release cholecysto

89 HA-DBCCR1 in NIH3T3 cells and human bladder tumour cell lines resulted in suppression of proliferati

90 ine NKG2D ligands Rae1beta or H60 in several tumour cell lines results in potent rejection of the tum

91 MS xenograft models except for an aggressive tumour cell line, RMS559.

92 Northern and RT-PCR analysis of a panel of tumour cell lines showed that LPHH1 expression was varia

93 log XRCC2 found in the MMR-deficient uterine tumour cell line SKUT-1 can confer thymidine sensitivity

94 Tumour cell lines stably transfected with LEF1(DN) or AP

95 d composition and parameters associated with tumour cell lines such as their sensitivity to hypoxia o

96 a probable germline mutation in a pancreatic tumour cell line suggests a role for BRCA2 in susceptibi

97 transcript is expressed in the human breast tumour cell line T-47D.

98 expressed channel protein in a human colonic tumour cell line T84.

99 Normal primary cells and tumour cell lines that express wild-type chfr exhibited

100 In contrast, the tumour cell lines that had lost chfr function entered me

101 gen of simian virus 40 (SV40 T-Ag) and human tumour cell lines that lack a functional retinoblastoma

102 our cells and that this effect is selective; tumour cell lines that overexpress PPM1D are sensitive t

103 that selectively reduces viability of human tumour cell lines that overexpress PPM1D.

104 In a panel of 16 human tumour cell lines, the anti-proliferative activity of AZ

105 e demonstrate that in amoeboid-like invasive tumour cell lines, the v-SNARE, VAMP3, regulates deliver

106 Interestingly, exposure of epithelial tumour cell lines to ALX in vitro resulted in potent act

107 Expression was recovered in tumour cell lines treated with 5-aza 2-deoxycytidine.

108 epithelial cell line MCF10A and the uMUC1(-) tumour cell line U87.

109 lysed a Birt-Hogg-Dube patient-derived renal tumour cell line (UOK257) that is devoid of the Birt-Hog

110 level of specific genes in a panel of human tumour cell lines using modified Southern blotting metho

111 hermore, constitutive ligand expression by a tumour cell line was inhibited by targeting short interf

112 DNA synthesis in some tumour cell lines was completely resistant to the anti-R

113 NORE1A expression in tumour cell lines was reactivated after treatment with a

114 s assessed by antiproliferation assay on two tumour cell lines, whereas for investigation of type of

115 C, 3/17 NSCLC, 1/6 colorectal and 3/9 kidney tumour cell lines, while NORE1B promoter was unmethylate

116 topic and disseminated syngeneic models, and tumour cell lines with or without mutations in Trp53 and

117 rest were found following treatment of human tumour cell lines with serum, 12-O-tetradecanoyl-phorbol

118 igh expression of STK15 mRNA was detected in tumour cell lines without evidence of gene amplification