ライフサイエンスコーパス: turbinate

1 iated lymphoid tissue lining the trachea and turbinate.

2 a dark crusted lesion developed on her nasal turbinate.

3 h grass or ragweed extracts on each inferior turbinate.

4 l examination findings of edematous and pale turbinates.

5 rgeted the olfactory epithelium in the nasal turbinates.

6 ion, but not on day 3, and only in the nasal turbinates.

7 icates to high titers in the lungs and nasal turbinates.

8 mainly in ventral and lateral regions of the turbinates.

9 XBB.1.5 improved viral control in the nasal turbinates.

10 ates with low nirmatrelvir exposure in nasal turbinates.

11 RS-CoV-2 virus titers in the lungs and nasal turbinates 4 days post-challenge of mice vaccinated with

12 (COVID-19) cases to give blood, saliva, mid-turbinate and fomite (phone) swabs, and 30-minute breath

13 ection in native multi-cell-type human nasal turbinate and lung tissues ex vivo, coupled with genome-

14 ed that bovine FLUDV replicated in the nasal turbinate and lungs of guinea pigs at high titers and wa

15 Histologic examination of the nasal turbinate and lungs revealed intense inflammatory infilt

16 in inoculated piglets necropsied at 5 dpi in turbinate and trachea, followed by tonsils, lungs, trach

17 lung, but replication was most efficient in turbinate and trachea.

18 grams/ml) detected four bands in solubilized turbinate and tracheal epithelial cells (53.7, 31.2, 28.

19 Sinonasal tissues including inferior turbinate and/or nasal polyps (NPs) and peripheral blood

20 High viral titers were obtained from nasal turbinates and lung tissues of directly inoculated anima

21 cterized by microscopic lesions in the nasal turbinates and lungs of all ferrets; however, Sw30 infec

22 ection in hamsters, replication in the nasal turbinates and lungs tended to be the most reduced for v

23 ficant defects in viral replication in nasal turbinates and lungs.

24 viral RNA and infectious virus in the nasal turbinates and lungs.

25 s of infectious virus were detected in nasal turbinates and nasal wash samples of A(H3N2)v-inoculated

26 ignificantly reduced viral load in the nasal turbinates and oropharyngeal swabs from NP-vaccinated ha

27 route, barcode compositions across the nasal turbinates and trachea were similar and highly diverse,

28 lage abnormalities in the basicranium, nasal turbinates and trachea.

29 syndrome-coronavirus 2, nasopharyngeal, mid turbinate, and nasal specimens are suitable in most case

30 s were collected by brushing of the inferior turbinates, and gene expression was interrogated by RNA-

31 d viral infection in the nasal washes, nasal turbinates, and lungs compared to unvaccinated animals.

32 2 RNA was only detected in nasal swab, nasal turbinates, and mesenteric lymph node, but no evidence o

33 btained from the inferior turbinates, middle turbinates, and nasal polyps of CRSwNP patients, we iden

34 um antibody titers, pathogens infected nasal turbinates, and neurotropic microbes invaded the brain.

35 > medium turbinate posterior (MTP) > medium turbinate anterior (MTA).

36 on of T cells and macrophages into the nasal turbinates, as well as migration and proliferation of B

37 istent inflammatory markers in the olfactory turbinates at 8 dpi despite clearance of the virus.

38 ptica is necessary to produce the lesions of turbinate atrophy and bronchopneumonia in pigs infected

39 Moderate turbinate atrophy and bronchopneumonia were found in mos

40 in a significant increase in the severity of turbinate atrophy induced by P. multocida compared with

41 given the parent strains, while there was no turbinate atrophy or pneumonia in pigs challenged with t

42 oxin (DNT), which has been implicated in the turbinate atrophy seen in cases of atrophic rhinitis.

43 Mild to moderate turbinate atrophy was apparent in pigs inoculated with s

44 was terminated on day 37, and the extent of turbinate atrophy was determined by using a morphometric

45 mild but statistically significant degree of turbinate atrophy.

46 24 h after challenge, and bilateral inferior turbinate biopsies were obtained 24 h after challenge, w

47 al swab samples, 71.7% (81 of 113) for nasal turbinate biopsy samples, 19.5% (22 of 113) for blood sa

48 2, preventing replication in lungs and nasal turbinates, body weight loss, cytokine storm, and lung p

49 lls were isolated and cultured from inferior turbinate brushings of healthy subjects (n = 8) and pati

50 mainly in the upper respiratory tract (nasal turbinates) but also in the lower respiratory tract of i

51 That is, the reassortants grew well in nasal turbinates, but only sporadically (if at all) in the tra

52 milar in primary differentiated ferret nasal turbinate cells, and similar viral titers were measured

53 ted NP patients for comparison with inferior turbinates collected from healthy controls.

54 nt mice have reduced complexity of the nasal turbinates, decreased sensory innervation of the OB, red

55 ificant relationship between the severity of turbinate degeneration and the number of P. multocida or

56 l the pigs were euthanized and the extent of turbinate degeneration was assessed by using a morphomet

57 Decongestion reduces blood flow in the nasal turbinates, enlarging the airway lumen.

58 virus to replicate more efficiently in nasal turbinate epithelium and subsequently transmit between f

59 xplants, we found that nasal polyps, but not turbinates, exhibit apical calcium responses to PAR-2 st

60 Imaging nasal polyps and control middle turbinate explants, we found that nasal polyps, but not

61 ovine choroid plexus (CP), testes (OAT-T3), turbinate (FLT), and intestinal carcinoma (ST6) cell lin

62 ring predicted and actual intermediate nasal turbinate geometries in scans taken from the same subjec

63 n contours of the nasal wall and the desired turbinate geometry, while the path planning algorithm ge

64 tors were moderately restricted in the nasal turbinates, highly restricted in lungs, and genetically

65 ve examined the association between inferior turbinate hypertrophy (ITH) and extraesophageal reflux (

66 mu isozyme reveal that the lateral olfactory turbinates I, Ib, II, IIb, and III display a greater int

67 2A mutant viruses were detected in the nasal turbinates, in addition to the lungs.

68 Gene expression analysis of the nasal turbinates indicated that 1-year-old female ferrets had

69 tection of low levels of subgenomic mRNAs in turbinates indicated that replication was aborted in imm

70 ulted in sloughing off of the OSE from nasal turbinates into the lumen of the nasal airway.

71 The occurrence of ethmoid turbinates is an important step in the evolution of mamm

72 the ferret respiratory tract, ferret ethmoid turbinate lined with olfactory epithelium favors replica

73 cant reduction of virus replication in nasal turbinate, lung, and brain was observed following nasal

74 tection in four discrete tissue types (nasal turbinate, lung, brain, and olfactory bulb [BnOB]) to cl

75 o significantly reduce viral titers in nasal turbinates, lungs, and olfactory bulbs.

76 isolated ciliated cells from both polyps and turbinates maintained basolateral PAR-2 polarization, su

77 gs; however, robust viral infection in nasal turbinate may outcompete the antibody with significant i

78 uman nasal mucosa obtained from the inferior turbinates, middle turbinates, and nasal polyps of CRSwN

79 n explant tissue model with ex vivo inferior turbinate mucosa obtained from patients with chronic rhi

80 ase chain reaction in nasal vestibule, nasal turbinate mucosa, and peripheral blood samples, along wi

81 pharyngitis, myalgias), staff obtained a mid-turbinate nasal swab in participants' homes.

82 d weekly SARS-CoV-2 testing by providing mid-turbinate nasal swabs for qualitative and quantitative r

83 Paired mid-turbinate nasal swabs were collected from university stu

84 Weekly mid-turbinate nasal swabs were tested for RSV using real-tim

85 ion, clinician-supervised self-collected mid-turbinate (nasal) swab specimens, and clinician-collecte

86 tein influenza A and B antigens in nasal mid-turbinate (NMT) swab specimens from symptomatic individu

87 culation to enhance replication in the nasal turbinate (NT) and study local B cell immunity.

88 virus was detectable in the lungs and nasal turbinate of mice without preexisting PR8 immunity, whil

89 ow levels of virus were present in the nasal turbinates of a few hamsters at 14 days p.i.

90 infection in the lungs but not in the nasal turbinates of hamsters intranasally challenged with SARS

91 ilar viral titers were measured in the nasal turbinates of infected ferrets.

92 possessing NA-F144C or NA-T342A in the nasal turbinates of one or several infected ferrets, respectiv

93 A low amount of virus was found in the nasal turbinates of only one of eight rMVA-vaccinated mice on

94 t in pigs inoculated with strain 4609, while turbinates of those infected with strain DBB25 developed

95 m only 1 of 12 animals and only in the nasal turbinates on a single day.

96 have recoverable virus in the lungs or nasal turbinates on days 3 or 5 postinfection and did not deve

97 messenger (m)RNAs were detected in the nasal turbinates or lungs as early as 2 d after challenge, ind

98 Nasal turbinates or swabs were collected from wild ducks, gees

99 e the establishment and use of a novel nasal turbinate organ culture to study the initial steps of vi

100 regional differences in the order: inferior turbinate posterior (ITP) > medium turbinate posterior (

101 inferior turbinate posterior (ITP) > medium turbinate posterior (MTP) > medium turbinate anterior (M

102 onvoluted peripheral channels of the ethmoid turbinates project to the ventral MOB.

103 atory regions, including middle and inferior turbinates, ranged from 72.51% - 92.17% for the linear i

104 decongestant reduces blood flow to the nasal turbinates, reducing tissue volume and increasing nasal

105 ly increases the cross-sectional area in the turbinate region and SAVR is reduced (median approximate

106 ity within the olfactory tissue, the lateral turbinate regions displayed a higher level of activity w

107 to 73.2]), as well as in anterior nasal/mid-turbinate samples (77.3% [95% CI 73.0 to 81.0]).

108 as found between consecutively collected mid-turbinate samples with both molecular (n = 74, 100% conc

109 Nasal fluid, urine, blood, and inferior turbinate scrapings were collected at the 3 time points

110 The huICV replicated in the nasal turbinates, soft palate, and trachea but not in the lung

111 nasal neurectomy combined with the inferior turbinate surgery between April in 2005 and March in 200

112 nasal neurectomy combined with the inferior turbinate surgery for severe perennial allergic rhinitis

113 nasal neurectomy combined with the inferior turbinate surgery is effective in alleviating clinical s

114 tion of SARS-CoV-2 in infected patients (mid-turbinate swabs and exhaled breath aerosol samples) in c

115 positive samples from infected patients (mid-turbinate swabs and saliva samples, 4000-8000 copies/mL)

116 Participants self-collected mid-turbinate swabs daily (days 1 to 14) for SARS-CoV-2 poly

117 um of 14 days and collected 5 sequential mid-turbinate swabs to measure viral shedding.

118 he nose and higher virus titers in the nasal turbinates than intratracheal inoculation.

119 olon, select lymph nodes, small bowel, nasal turbinates, the genital tract and lung.

120 and migration were downregulated in inferior turbinate tissue after treatment with dupilumab.

121 ers in ferret nasal wash specimens and nasal turbinate tissue correlated positively with peak titer i

122 (61.03 pg/mg of tissue) compared to inferior turbinate tissue from controls (7.17 pg/mg of tissue [P

123 riety of solid and liquid specimens, such as turbinate tissue homogenate and lung lavage fluid, as we

124 nd porcine respiratory coronavirus (PRCV) in turbinate tissue homogenate.

125 tologic lung, lymph node, trachea, and nasal turbinate tissue sections.

126 Nasal turbinate tissue viability and physiological functionali

127 s correlated positively between ferret nasal turbinate tissue, lung tissue, and nasal wash specimens,

128 m or supernatants of cultured nasal polyp or turbinate tissues of N-ERD patients or healthy controls

129 nst SARS-CoV-2 replication in lung and nasal turbinate tissues, cytokine storm, and lung pathology.

130 SARS-CoV-2 productively infected the nasal turbinate tissues, predominantly targeting respiratory e

131 odel of HCMV infection in native human nasal turbinate tissues.

132 of CFU per gram of tissue recovered from the turbinate, trachea, and lung also demonstrated significa

133 Nasal turbinate, trachea, and lung were the main-but not the o

134 t a gull-origin H10N7 IAV replicated well in turbinate, trachea, and lung, but replication was most e

135 Viral antigens were detected in nasal turbinate, trachea, lungs, and intestine with acute bron

136 with virus replication detected in the nasal turbinates, trachea and lungs up to the study endpoint,

137 Following exposure, the nasal turbinates, trachea, and lungs were collected and the nu

138 s reduced the virus load in the lungs, nasal turbinates, trachea, and nasal washes.

139 amage, robust infection is observed in nasal turbinates treated within 1-3 days.

140 ized groups: nasal septum variations, middle turbinate variations, uncinate process variations, and e

141 Nasal scrapings from both inferior turbinates were obtained before and 24 h after challenge

142 agent isolated from the squirt Ecteinascidia turbinate, which alkylates DNA in the minor groove at GC

143 tis typically have erythematous and inflamed turbinates with serous secretions that appear similar to