ライフサイエンスコーパス: turn out

1 Because results often do not turn out as expected, anticipating failure is useful, an

2 To understand why molecular evolution turned out as it did, we must characterize not only the

3 These turn out, as we demonstrate by a bonding analysis, to be

4 e have identified a BACE1 cleavage site that turns out be highly conserved among neuregulin-1 paralog

5 g from simple cycloisomerization, whereas it turned out chemoselective toward the formation of the do

6 Herein, a structure-based lead optimization turned out into a small series of analogues, where 8 is

7 to choose a less familiar option that might turn out more advantageous (and thereby provide informat

8 gles, and life at the molecular scale is, it turns out, no exception.

9 The speckles turned out not to be a meaningless artifact, but rather

10 is factors in pre-ribosomal particles, which turned out not to be pre-40S but 80S-like ribosomes.

11 This turned out not to be so.

12 Perhaps predictably, this turns out not to be a uniform process.

13 This claim and others like it turn out, on examination, to be surprisingly broad, and

14 the constructed maps from the forward model turned out statistically indistinguishable, thus providi

15 It turned out that 4 d of deprivation were sufficient to in

16 It turned out that 5, or its precursor 3, can even be emplo

17 It turned out that a two-step pathway, where H2 cleavage ta

18 regulated by circulating glucose, but it has turned out that amino acids also play an important role

19 It turned out that fluorescence activation of the dye/quenc

20 It turned out that four preliminary experiments and prior i

21 It turned out that patawa had a stronger antioxidant activi

22 the translocon, however, in recent years it turned out that prolonged ER residence allows O-mannosyl

23 ted that SepF is membrane associated, and it turned out that purified SepF not only binds to lipid me

24 It turned out that the process occurred in a peculiar way,

25 It turned out that the three experimental optimization and

26 It turned out that treatment of N-chlorodialkylamines with

27 Surprisingly, it turns out that achieving a system with contiguous column

28 It turns out that due to a phenomenon similar to Anderson l

29 It turns out that E. coli and some other rod-shaped bacteri

30 It turns out that it required parallel developments in mass

31 It turns out that local measurement (i.e. opening one of th

32 It turns out that Na(+) and Cl(-) ions leak through a membr

33 Surprisingly, it turns out that platelets support the recruitment of leuk

34 It turns out that renal osmolytes fall into three distinct

35 It turns out that the DDR factor p53 takes center stage dur

36 It turns out that the fascinating properties of these mater

37 It turns out that the FIV tetherin antagonist is also its E

38 It turns out that the GFP tagging location and the fusion p

39 It turns out that the lattice mismatch of the surface with

40 Moreover, it turns out that the localization of dyneins in the periph

41 It turns out that the number of ligand molecules that are n

42 It turns out that the optimal motifs emerging from this fra

43 It turns out that the overall selectivity of the reaction i

44 It turns out that the parameters [Formula: see text] and [F

45 It turns out that the statistical differences between codin

46 Thus, it turns out that the two longer time constants do not repo

47 st separate for a Q(II) phase to form and it turns out that the work of their unbinding can be larger

48 If it turns out that there are different pathogenic pathways i

49 It turns out that this protein binds specifically to concav

50 It turns out that three major SDT patterns have developed a

51 As it turns out, the accuracy of identification rises signific

52 As it turns out, this is the shape of a common household strai

53 As it turns out, this seemingly simplistic one-dimensional mod

54 and the New York Post-Graduate were already turning out thousands of physicians who considered thems

55 wn as Lagrangian coherent structures (LCSs), turn out to admit highly attracting cores that lead to i

56 This may or may not turn out to be a common feature of plant secondary metab

57 Very oblique waves may turn out to be a crucial agent of energy redistribution

58 measured with fdOCT, RGC layer thickness may turn out to be a more direct and valid indicator of the

59 Sertraline, unlike venlafaxine, may turn out to be a true environmental threat due to its ac

60 ia for the diagnosis of malignancy, yet they turn out to be benign, because they belong to a group of

61 tial genes identified by genetic screens may turn out to be components of selfish elements.

62 Surprisingly, three-dimensional pseudopods turn out to be composed of thin (<0.75 microm), flat she

63 creasing hot flashes in women may not always turn out to be effective in men.

64 Although Levy flights turn out to be efficient search processes when the targe

65 of an invariant diffuse layer effect, which turn out to be entirely analogous to those for a surface

66 The dynamics of normalized weights turn out to be equivalent to those of the constrained pr

67 These species may turn out to be essential performers or partners in new i

68 ear electric quadrupolar coupling parameters turn out to be extremely sensitive experimental probes f

69 tforward answers, which on closer inspection turn out to be fiendishly complex.

70 the two areas for dealing with these issues turn out to be identical, opening ways for mutually bene

71 ions reduce to a mere handful, some of which turn out to be identical.

72 Paradoxically, however, they turn out to be incorrect stereotypes that even correlate

73 Biomarker panels may turn out to be more accurate than each individual compon

74 Moreover, our H1 --> IMR90 predictions turn out to be more accurate than IMR90 --> IMR90, poten

75 'receptive substance' by Langley, that would turn out to be nAChRs, and 'Vagusstoff' (acetylcholine)

76 These results may turn out to be of immense consequence towards developing

77 at selectively target its enzymatic activity turn out to be potent only for lymphoma cells with EZH2-

78 a particular dynamical model, whereas others turn out to be quite robust across different models.

79 asurements to substantiate such a hypothesis turn out to be rather difficult and have rarely been per

80 y in the focus of the field of photovoltaics turn out to be rather expected from the point of view of

81 esponses, when compared against logic, often turn out to be rationally justified when seen in the ric

82 o exhibit properties in their own right that turn out to be relevant in catalysis.

83 mplectic embeddings in four dimensions which turn out to be sharp in the above cases.

84 nt technological advances, could potentially turn out to be significant pathways to knowledge.

85 O vacancies turn out to be stable in O-poor environment, in agreemen

86 t the C-termini of alpha-helices, and niches turn out to be the most common C-terminal features of al

87 This non-invasive and inexpensive tool may turn out to be the preferred treatment option.

88 The margins of the grana turn out to be the site of protein degradation, well sep

89 The critical sequences d turn out to be those that accumulate rapidly in X in the

90 phenotypic data are obtained, causation can turn out to be unexpectedly simple.

91 ; while Al7Mg3(-), Al11Mg(-), and Al11Mg2(-) turn out to be unexpectedly stable at electron counts of

92 ld such topological inter-module connections turn out to constitute a form of functional coordination

93 the smallest spectral gaps; such small gaps turn out to correspond to regimes where the low-frequenc

94 Cascade switched flipper probes turn out to excel with chemical stability, red shifts ad

95 e these new transitions or reaction channels turn out to have a transparent physical interpretation:

96 Our findings turn out to indicate interesting connections and possibi

97 In this framework strong liquids turn out to lie the closest to a critical point associat

98 initially thought to be location-specifiers, turn out to respond promiscuously to a wide range of sti

99 heir 3'-end interaction sites in the 5'-UTRs turn out to simultaneously contain 5'-end interaction si

100 nces from genomic DNA, one of which (PtACO2) turned out to be >98% identical to PtACO1 in the nucleot

101 cificity of quiescent CNV detection by OCT-A turned out to be 81.8% and 100%, respectively.

102 erence and our algorithmic characterisation) turned out to be [Formula: see text] category on the LOC

103 The introduction of ionic liquids turned out to be a breakthrough in the field of Green Ch

104 with Arg(19) of PrRP20 led to D6.59R, which turned out to be a constitutively active receptor mutant

105 HS-SPME-MS-enose turned out to be a fast, cost-effective and objective ap

106 cylglycerol O-Acyltransferase 1 (DGAT1) gene turned out to be a functional and positional candidate g

107 On the other hand, CpA turned out to be a good substrate for the Cu(II) complex

108 o maintain cellular memory of homeotic genes turned out to be a highly conserved and sophisticated ne

109 didate for optimization studies (compound 1) turned out to be a mixture containing two unknown specie

110 Terahertz (THz) absorption spectroscopy has turned out to be a powerful tool to study (bio)molecular

111 clodal, c[-Arg-d-Phe-d-Lys-d-Dmt-] (2), also turned out to be a selective MOR antagonist with 1 nM bi

112 This presumed tolerogenic action turned out to be a sensitization process with the develo

113 The best extraction method turned out to be a sequential extraction in the headspac

114 Sepsis turned out to be a significant predictor of posttraumati

115 Finally, molecular iodine turned out to be a similar if not superior catalyst for

116 One of these mutants, caa39, turned out to be a weak mutant allele of the Topoisomera

117 The model turned out to be able to account for the structural vari

118 vity of the cinnamic anilide mPTP inhibitors turned out to be additive with that of CsA, suggesting f

119 greater rigidity of the ligand molecule and turned out to be advantageous, if not mandatory, for (cl

120 Lupin seed globulins turned out to be almost totally susceptible to chymotryp

121 othiazol-2-yl)-4-propoxybenzamide (3), which turned out to be an analog of the drug nitazoxanide (1).

122 hich upon treatment with Ag[CB(11)H(6)Cl(6)] turned out to be an excellent catalyst for the transform

123 mental agents or genetic defects, and IsoMut turned out to be an invaluable tool in the analysis of s

124 iviral therapeutics, but drug resistance has turned out to be an obstacle in the clinic.

125 y current amplitudes of EAAT5 anion channels turned out to be approximately twice as high as single-c

126 uated in combination with flow cytometry and turned out to be around 25% (cells entering the ICP-MS f

127 -14PD (lacking 14 phosphoacceptor sites) and turned out to be based on a phosphorylation-independent

128 Gd-PyMTA turned out to be cell compatible and was proven to be in

129 rst identified in CDK and Src kinases, which turned out to be central to understanding of how kinase

130 ents being less abundant in most tissues, it turned out to be challenging to enrich and identify GKAP

131 on time to a clinically acceptable level has turned out to be challenging.

132 In both cases, Laplacian regularization turned out to be crucial for achieving a reasonable gene

133 of substrate conformers during the reaction turned out to be crucial in obtaining an accurate predic

134 The temporal order of spikes turned out to be crucial.

135 eceptors, etc.), most of the over-responders turned out to be deleted of proteins functioning in the

136 rs with the dark homogeneous streaks pattern turned out to be different primary melanomas from the sa

137 arious stem and progenitor cells, Prominin-1 turned out to be dispensable for precursor cell prolifer

138 Accordingly, draining lymph nodes turned out to be dispensable for the proliferation of tu

139 Many of the most informative predictions turned out to be either recovering existing knowledge ab

140 This turned out to be especially demanding in large groups.

141 olypeptide appears to be highly flexible and turned out to be essential for proper functioning of Fts

142 ing via gibberellic acid, on the other hand, turned out to be essential for the increase in APR mRNA

143 process of V(D)J recombination per se, CTCF turned out to be essential to control order, lineage spe

144 ory sensory cells of insects and vertebrates turned out to be evolutionarily related.

145 ADDOL-related diols with an acyclic backbone turned out to be excellent ligands for asymmetric gold c

146 However, development of such agents has turned out to be extremely challenging, with major hurdl

147 This route turned out to be fairly selective and thus allows for th

148 icipated to be a strong event in early 2014, turned out to be fairly weak.

149 A and DNMT3B, the subsequent oxidation steps turned out to be far more complex.

150 ic transcription factor binding (ASTF), have turned out to be far more pervasive-affecting many non-i

151 These molecules turned out to be highly efficient fluorescent molecular

152 ied as the receptor-like kinase SR160, which turned out to be identical to the brassinosteroid recept

153 Glu572 turned out to be important for osmosensing in E. coli ce

154 hoice of catalytic system as well as solvent turned out to be important in order to ensure a high che

155 ns used in nanomedicine and nanoformulations turned out to be inapplicable to clinical applications.

156 Surprisingly, this simple model has turned out to be incorrect, and the dominant pathway has

157 rocess of accumulation of damage, ageing has turned out to be influenced by mechanisms that show stro

158 but its behavior in the RNA environment also turned out to be informative.

159 However, 5-methylcytosine has turned out to be just one component of a dynamic DNA epi

160 s, but none of the PFNs in the present study turned out to be malignant.

161 in(-1) very sharp, pulled nanospray emitters turned out to be mandatory for the generation of a stabl

162 The corresponding 5-isopropylthiohydantoins turned out to be more prone to racemization at C-5 durin

163 d to T-Lite SF under low intensity UV, cells turned out to be more sensitive to cadmium, a priority p

164 However, the situation has turned out to be much more complex than originally envis

165 The distribution of filament lengths turned out to be narrow, which we explained by the negat

166 Curiously, the obtained structural models turned out to be nearly indistinguishable from the model

167 Mammalian TRPs, TRPCs, turned out to be nonselective, calcium-permeable cation

168 The presence of acyl groups turned out to be of paramount importance for an efficien

169 ce its discovery in the late 1990s, Pten has turned out to be one of the most important tumor suppres

170 ysregulated IL-17 and psoriasis pathogenesis turned out to be particularly evident, a number of monoc

171 de Helm 15--where a simple military exercise turned out to be perceived as the beginning of a new civ

172 On further investigation, these fluorophores turned out to be potential biomarkers; in particular, th

173 the emergence process and sub-lethal effects turned out to be potentially relevant model extensions.

174 ker residence time as a function of voltage, turned out to be practically the same for all six cases

175 ripheral interface to the varphi29 procapsid turned out to be rather soft.

176 ered a new polymerase, pol V, whose activity turned out to be regulated by bound molecules of RecA pr

177 Unexpectedly, PvdN turned out to be required for a specific modification of

178 Italian saffron turned out to be richer in total crocins and safranal co

179 The following variables turned out to be significant predictors: more expected h

180 ectra and its average relative concentration turned out to be significantly lower in clams than in mu

181 Phlebotomy need turned out to be significantly lower in patients taking

182 Several of the new peptides turned out to be significantly more potent than their GO

183 ving a false alert because the ground motion turned out to be significantly smaller than the system e

184 Yet, only one of the eight diastereomers turned out to be stable in the solvent mixture that had

185 Insular strokes turned out to be strongly associated with headache.

186 oximal and distal phosphoacceptor sites both turned out to be sufficient to induce WT-like desensitiz

187 nts of the number of cases of disease, which turned out to be surprisingly low for an influenza pande

188 of mexiletine (metabolite switch), which has turned out to be tainted with common toxicity.

189 have to be soluble in the same solvent which turned out to be tetrahydrofuran, THF.

190 ery component originally claimed as catalyst turned out to be the active ingredient in the end.

191 There can be little doubt that 2006 turned out to be the annus horribilis for therapeutic cl

192 AITC turned out to be the best stimulus because the coughing

193 line based on optimal transport theory, this turned out to be the case.

194 bled into a career in plant pathology, which turned out to be the ideal job for me.

195 The free thiol group of Cys(121) turned out to be the major binding site.

196 Furthermore, three linked SUMO units turned out to be the minimum length of a substrate-linke

197 In this sense, 2(2-) turned out to be the most active catalyst due to the dou

198 The phosphazene base BEMP turned out to be the most active organo-catalyst compare

199 tudies, the Aib-containing complexes 3 and 4 turned out to be the most effective toward all the human

200 by a subsequent lipase-catalyzed resolution turned out to be the most efficient route, leading to th

201 d nucleophiles: the 1-dodecanethiolate anion turned out to be the most general and efficient reagent,

202 -DSB)2(mu-OH)3(H2O)4] as a pure phase, as it turned out to be the precursor of (O2H3)Sc-MOF.

203 pathways targeted by sphingolipid metabolism turned out to be the secretory route of newly synthesize

204 inating laboratory Escherichia coli strains, turned out to be the well-known lambdoid phage phi80.

205 Despite the structural simplicity, the probe turned out to be unprecedentedly highly sensitive to eve

206 s4B/PDEdelta complex formed in bulk solution turned out to be unstable in the presence of heterogeneo

207 latelet count and decreased hemoglobin) have turned out to be useful in risk prediction.

208 Both types of ligands turned out to be versatile catalysts for the Henry react

209 rare earth amidinates and guanidinates have turned out to be very efficient homogeneous catalysts e.

210 the phosphorescence quantum yield invariably turned out to be very low, about 0.02 - 0.04% at ambient

211 The oligomerization kinetics turned out to be very sensitive to the reaction conditio

212 The complex 1 turned out to be very stable under physiological conditi

213 zed both in the solid state and in solution, turned out to exhibit a dual role, i.e., the oxidation o

214 Members of the same forma specialis turned out to group together, with cucurbit-infecting st

215 Moreover, this protocol turned out to have a broad scope, allowing the preparati

216 s, the weaker decomposer in this experiment, turned out to have a high content of genes involved in c

217 tion, carbonyl cleavage, and redox reactions turned out to have a large impact on the diversity the M

218 ly normal neuroanatomical profiles, who also turned out to have the least abnormal cognitive and cere

219 2) were active, most of the anilides (n = 0) turned out to moderately or strongly inhibit 17beta-HSD2

220 widespread, conserved proteins many of which turned out to participate in translation, in particular

221 the types detected throughout the study, 24% turned out to persist in the parents and only 11% in the

222 Compound 1 turned out to possess an IC50 of 93.7 and of 4.6 nM on M

223 with XO entrapped Ta2O5 nanofibers has been turned out to possess maximum sensitivity amongst the sy

224 Although phenyl groups turned out to provide significantly less solubilization

225 the real maximum likelihood function, which turned out to provide us with significantly more accurat

226 SLC2A1 turned out to represent the hub of a functional network,

227 , the few-nanometer-sized alpha-CsPbI(3) QDs turned out to retain high photoluminescence and highly c

228 ound 9c showed low eukaryotic cell toxicity, turning out to be an excellent lead candidate for precli

229 th platelet activation and aggregation, thus turning out to be more effective than the analogues quer

230 g efflux pump activity of mycobacteria, thus turning out to be promising multidrug-resistance-reversi

231 one genetic model species after another are turning out to have limited abilities to interbreed, as

232 traction of intrinsic structural information turns out to be a compelling but challenging need.

233 d size; the larger, overall place field size turns out to be a consequence of jitter across trials.

234 = 2.1478 compact galaxy, which-surprisingly-turns out to be a fast-spinning, rotationally supported

235 ures of analytes via Delta(f)H of ions which turns out to be a good quantitative structure-fragmentat

236 However, it turns out to be a highly nontrivial computational task t

237 mal activation of the photocycle, melanopsin turns out to be a highly sensitive pigment consistent wi

238 The western boundary current turns out to be a key region for the penetration of near

239 inducer exclusion or CAP activation, but it turns out to be a natural consequence of the model.

240 Quantum contextuality turns out to be a necessary resource for universal quant

241 Combined with multivariate data analysis, it turns out to be a powerful tool for profiling of many sa

242 This optical technique turns out to be a powerful way to monitor, in real-time,

243 used in organometallic chemistry before but turns out to be a sensitive probe that deserves more att

244 ship between the internal energy and xi that turns out to be a sure-tell sign of being in the glassy

245 most counterintuitive feature of the theory, turns out to be a useful resource for communication acro

246 stemic immune stimulation, which in addition turns out to be age dependent.

247 The amount of information encoded turns out to be almost completely dependent upon the tot

248 M. sieversii in Xinjiang of China turns out to be an "ancient" isolated ecotype not direct

249 Complex 4(2-) turns out to be an exceptional water oxidation catalyst

250 articles as well as to model charge barriers turns out to be appropriate to approach an understanding

251 The structure of the FIM turns out to be block-diagonal, revealing hidden paramet

252 oupling across the non-magnetic Ir substrate turns out to be chiral with a 120 degrees rotation betwe

253 haracterized by dynamic heterogeneity, which turns out to be critical in reproducing the experimental

254 of molecular brightness to be handled which turns out to be critical to the fidelity of the final im

255 al low-level HR in BRCA1-mutant cancer cells turns out to be critically important for their survival

256 ies lend support to such a model, which also turns out to be crucial for a better understanding of th

257 ose a flexible notion of conservation, which turns out to be crucial for the quality of the resulting

258 adiponectin-based drug development approach turns out to be difficult due to extremely high serum le

259 couplings and short intermolecular distances turns out to be disadvantageous for efficient charge tra

260 th a wind flow, we show that the instability turns out to be driven by resonant grain trajectories, w

261 GTPase IFT27, a member of the IFT-B complex, turns out to be essential for retrograde cargo transport

262 hod resulting in possible RNA fragmentation, turns out to be fully compatible with 3' scRNA-seq.

263 The resulting decoherence rate turns out to be given by a surprisingly simple equation.

264 l to match neural data, its top output layer turns out to be highly predictive of IT spiking response

265 This turns out to be important for hESC pluripotency.

266 The interdomain motion turns out to be limited.

267 arge sums on countermeasures and the problem turns out to be minor or even nonexistent, we will have

268 tes to be connected just by a flexible chain turns out to be more a rough approximation than a good m

269 The proposed approach turns out to be more powerful in identifying time course

270 by mapping on a simple stochastic model and turns out to be of the order of gamma(HB) approximately

271 Homotherium turns out to be only distantly related to the well-known

272 cytosolic enzyme aldehyde dehydrogenase 1A3 turns out to be overexpressed in these kinds of cells, p

273 The resistivity upturn turns out to be qualitatively contradictory to weak loca

274 relevant figures: (1) the sensitivity, which turns out to be sample-dependent, as expected, (2) the p

275 The cascade reaction turns out to be selective with respect to propyne-allene

276 objects (within a fixed homotopy class) that turns out to be similar to the Reidemeister-Singer theor

277 The discrete case turns out to be similar, but the behavior can be exagger

278 ing and Ca(2+) uncaging here reveal that CDF turns out to be strikingly faster, more Ca(2+) sensitive

279 ingle interaction of alpha-actinin and titin turns out to be surprisingly weak if force is applied.

280 ariance without sacrificing discriminability turns out to be that the learned and novel objects trans

281 m target positioning regular Brownian motion turns out to be the advantageous search strategy.

282 er tradeoff between precision and recall and turns out to be the best one when incomplete annotation

283 solution of the biomass optimization problem turns out to be the dominant attractor of the metabolic

284 the barrier associated with this interaction turns out to be the limiting one.

285 al silencing complex assembled by HPV E2 and turns out to be the long sought cellular corepressor tha

286 The surface density of SNARE proteins turns out to be the most critical parameter, which contr

287 Particularly, the amino acid arginine (R) turns out to be the most favorable target of amino acid

288 target, needs a large library of siRNAs and turns out to be time-consuming and expensive.

289 The same turns out to be true for the UKF.

290 The Acg family turns out to be unusual flavin mononucleotide (FMN)-bind

291 the unfolded state of these proteins, which turns out to be unusually compact, strongly deviating fr

292 nsional query data, this retrieval criterion turns out to be very noisy as well.

293 two-photon excited fluorescence of Nile Red turns out to be very responsive to substitution, and the

294 The alpha-pay sub-model turns out to closely resemble the original "concessions"

295 robabilities of being active, this threshold turns out to depend on the duration of casual partnershi

296 The AI turns out to describe pi-delocalization in a balanced wa

297 ional skew model, and the beta-pay sub-model turns out to have properties similar to the "restraint"

298 While zone II turns out to have rhombohedral BiFeO3, the crystal struc

299 as a byproduct of the photochromic reaction turns out to prevent the desired high reversibility for

300 The neutron doping process turns out to produce spatially uniform doping throughout