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1 lar DNA, kin recognition, and cell motility (twitching).
2 2013, 159 patients consented and enrolled in TWiTCH.
3 e identified to positively impact quadriceps twitch.
4 and increasing the amplitude of the cardiac twitch.
5 le were those activated by the evoked muscle twitch.
6 00 ms of whisker movements, especially after twitches.
7 ons of corollary discharge are absent during twitching.
8 D With Transfusions Changing to Hydroxyurea [TWiTCH]).
10 before (M3) and after (M2 and M3) training: twitch (56% vs. 62%), lift (6% vs. 5%), and extend (37%
11 ts that spinal reflexes are inhibited during twitching [9-11], this finding suggests that twitches tr
12 ides evidence that muscle stimulation evoked twitches - a physiological stimulus for Golgi tendon org
14 py) of more-complex, multi-joint patterns of twitching; again, wild-types/heterozygotes exhibited dev
15 on in hSOD1(G93A)-UeGFP mice, and their slow-twitch alpha and gamma motor neuron identity was confirm
22 econdaries, which innervate superficial fast-twitch and slow fibers via medial and septal nerves, fol
25 ning at a frequency of 2048 Hz, we show that twitch and tetanic force responses to electric pulses fo
26 raphy and muscle force measurements (maximum twitch and tetanic forces) were obtained along with musc
27 results in 3.05 and 2.28 times increases in twitch and tetanic forces, respectively, suggesting that
28 mulated Ca(2+) concentrations in the case of twitch and tetanus, corresponding to different applied c
29 es of muscle fibers called type I "red" slow twitch and type II "white" fast twitch, which display ma
32 esults show that the forces generated during twitching and gliding have complementary characters, and
33 ing swimming in aqueous media, and swarming, twitching and gliding on solid and semi-solid surfaces.
35 Neurons in the RN fired phasically before twitching and wake movements of the contralateral foreli
37 Mdivi-1 also significantly increased basal, twitch, and tetanus stresses, as measured using the Musc
38 iderable variability in the features of head twitches, and behaviors such as jumping have similar cha
42 results also highlight the potential use of twitching as a uniquely informative diagnostic tool for
47 e symptoms of schizophrenia, it reduced head twitch behavior induced by DOI, but it failed to inhibit
51 brief bursts immediately following myoclonic twitches; by P12, theta oscillations are expressed conti
54 xpectedly revealed a category of reflex-like twitching-comprising an agonist twitch followed immediat
57 contraction (100 Hz, 500 ms) and to rhythmic twitch contractions (4 Hz, 30 s) was impaired at 5 days,
58 his was achieved by comparing the effects of twitch contractions and stretches as donor inputs onto t
60 thesis that intramuscular stimulation evoked twitch contractions could be used to naturally bias acti
63 sed blood flow and interstitial PO(2) during twitch contractions reflecting impaired O(2) delivery-to
68 arvae exhibited abnormal swimming, increased twitching, defective eye movement and pectoral fin contr
69 development of local and global features of twitching, demonstrating that twitching is shaped by sen
72 mouse myotubes were stimulated by ACh, with twitch duration and frequency most closely resembling th
73 ectromyography recordings also showed muscle twitches during sleep and the dissociation of theta acti
76 nists enhance the function of slow- and fast-twitch dystrophic muscles and because their use is limit
80 threshold) afferents activated by the muscle twitch evoked by electrical stimulation of the facial ne
83 pacities of these isoforms different in fast-twitch extensor digitorum longus (EDL) and slow-twitch s
84 he specific force of contraction of the fast-twitch extensor digitorum longus muscle yet had no effec
86 -Fc) completely restore the function of fast-twitch extensor digitorum longus muscles in dystrophic m
87 tile force that was not observed in the fast-twitch extensor digitorum longus muscles of R58Q vs. wil
90 ggest that: (1) ERK1/2 are critical for slow-twitch fiber growth; (2) a defective gamma/epsilon-AChR
91 etal muscle, specifically implicated in slow-twitch fiber-type specification, function, and cardiomyo
92 low-twitch (ST), oxidative (relative to fast-twitch) fiber proportion is prevalent in chronic disease
97 ainly in muscles with a predominance of fast-twitch fibers, suggesting that fiber type-specific lipid
98 on of the nNOS promotor in soleus (Sol; slow-twitch fibre dominant) and extensor digitorum longus (ED
100 eed running and an important glycolytic fast-twitch fibre recruitment boundary in the rat) principall
101 reflex-like twitching-comprising an agonist twitch followed immediately by an antagonist twitch-that
102 d uses frequency-dependent modulation of the twitch for force potentiation performs best for the slow
103 ed different types of motility, with reduced twitching for DeltafimX and reduced swimming for Deltadi
104 atic digestion, attached to carbon rods, and twitch force and intracellular Ca(2+) were measured.
105 onvolitional objective technique, quadriceps twitch force generation in response to femoral nerve mag
106 rmed by assessing their calcium homeostasis, twitch force generation, and response to beta-adrenergic
110 rroborated by muscle physiology studies with twitch force, tetanic and eccentric contraction all bein
111 bled as a functional syncytium; (2) systolic twitch forces at a similar level as observed in bona fid
112 ical stimulation, individual FDB fibers show twitch forces of 0.37 +/- 0.15 muN and tetanic forces (1
113 aracterized by marked overexpression of fast-twitch genes and postnatal development of a fatal dilate
114 oth slow-twitch oxidative myofibers and fast-twitch glycolytic myofibers that differentially impact m
116 N is also a major source of motor output for twitching in early infancy, a period when twitching is a
118 gated the contributions of proprioception to twitching in newborn ErbB2 conditional knockout mice tha
119 asured in the biceps muscle using a modified twitch interpolation technique to provide an index of ce
120 ntrol experiments verified that these evoked twitches involved neuromuscular transmission and faithfu
121 ensory feedback from sleep-related myoclonic twitches is thought to drive activity-dependent developm
122 or twitching in early infancy, a period when twitching is an especially abundant motor behavior.
128 eved maximum peak stress of 6.5 mN/mm(2) and twitch kinetics approaching reported values from adult h
129 muscles showed that the increased force and twitch kinetics because increased pacing or beta1-adrene
130 ted by the observation that reafference from twitching limbs reliably and substantially triggers brai
132 g fluorescent dye injected into fast or slow twitch lower extremity muscle with slice recordings from
133 s characterized by increased myoglobin, slow twitch markers [myosin heavy chain 7 (MyH7), succinate d
135 re new ideas about the functional roles that twitching might play in the self-organization of spinal
137 dynamics and rule-based simulations to study twitching-mode motility of model bacilliforms and show t
138 confidence interval, 1.19-2.57) and reduced twitching motility (odds ratio, 1.43; 95% confidence int
139 ycosylation, reduced its capacity to inhibit twitching motility (~57%), without reducing pili binding
141 lting transgenic strains showed differential twitching motility and biofilm formation while maintaini
142 promote different characteristics, favoring twitching motility and biofilm formation, respectively.
143 a, the Pil-Chp system regulates T4P-mediated twitching motility and cAMP levels, both of which play r
144 eat-denatured DMBT1 lost capacity to inhibit twitching motility and showed reduced pili binding (~40%
145 ly system, which promotes surface-associated twitching motility and virulence, is composed of inner a
147 y, jerky slingshot motions characteristic of twitching motility comprise the transition region betwee
151 Therefore, DMBT1 inhibition of P. aeruginosa twitching motility involves its N-glycosylation, its pil
152 al bacteria Myxococcus xanthus, we know that twitching motility is under the dependence of the small
154 ns of propulsion has much in common with the twitching motility of heterotrophs such as Pseudomonas a
156 The model can successfully predict upstream twitching motility of rod-shaped bacteria in shear flows
159 swarming motilities powered by flagella, and twitching motility powered by Type IV pili, little is kn
160 position 54) that does not activate fimU or twitching motility was compared to PAO1, PAO1 algRD54E,
161 d Pseudomonas aeruginosa pili, and inhibited twitching motility, a pilus-mediated movement important
163 of diverse functions, including attachment, twitching motility, biofilm formation, and horizontal ge
164 ce structures, involved in processes such as twitching motility, biofilm formation, bacteriophage inf
165 only uses type IV pili for surface-specific twitching motility, but also as a sensor regulating surf
166 nd are important for processes as diverse as twitching motility, cellular adhesion, and colonization.
167 enally diverse array of functions, including twitching motility, DNA uptake and microcolony formation
169 host cell attachment, biofilm formation, and twitching motility, making this system a promising targe
170 cterial species, for processes as diverse as twitching motility, natural competence, biofilm or micro
171 is required for the coordinate activation of twitching motility, rhamnolipid production, and swarming
172 in covalent homo- or heterodimers eliminated twitching motility, suggesting that specific PilNO confi
173 were significantly impaired in T4P-mediated twitching motility, whereas the motility of the N3 mutan
181 ve toward chemoattractants using pili-based "twitching" motility and the Chp chemosensory system.
182 xtraocular muscles contain singly innervated twitch muscle fibers (SIF) and multiply innervated nontw
183 rated calcium entry (SOCE) in fast- and slow-twitch muscle fibers from normotensive Wistar-Kyoto rats
185 ingly, axonal dieback occurs first from fast-twitch muscle fibers, whereas slow-twitch fibers remain
187 ted with larger cross-sectional area of fast-twitch muscle fibres and favoured strength/power vs. end
188 ne were strongly associated with larger fast-twitch muscle fibres and strength/power performance vers
193 sistent with the high expression in the slow-twitch muscle, suggests that this variant may contribute
194 : synaptic strength was rescued only in slow-twitch muscle, while contractile strength was improved o
197 ties and physiological function only of slow-twitch muscles and largely sparing fast-twitch muscles.
199 E and that tetanic force development in slow twitch muscles is supported by the dynamic interaction b
200 cts muscle mass over time, particularly fast-twitch muscles, which should be taken into consideration
205 l-angle X-ray diffraction measurements of WT twitching muscles during diastole revealed stretch-induc
206 ranscription of myo18b is restricted to fast-twitch myocytes in the zebrafish embryo; consistent with
207 ession of genes encoding normal cardiac slow-twitch myofiber proteins and pathologically increased ex
208 alance in gene expression for fast- and slow-twitch myofiber proteins, and rescued cardiac function i
212 ite to the notion that sensory feedback from twitches not only activates sensorimotor circuits but mo
213 REM) sleep, infant mammals exhibit myoclonic twitches of skeletal muscles throughout the body, genera
215 had a rapid onset of progressive confusion, twitching of the face and hand, and abnormal basal gangl
216 The results also indicate that when bacteria twitch on groove surfaces, they are likely to accumulate
217 ent Method (DEM) proposed to study bacterial twitching on flat and groove surfaces under shear flow c
218 le and Law of Diffusion) in contracting fast-twitch oxidative mixed gastrocnemius muscle (MG: 9% type
219 pression and the proportion of type IIa fast-twitch oxidative muscle fibers, which was verified using
220 Skeletal muscle is composed of both slow-twitch oxidative myofibers and fast-twitch glycolytic my
225 mical results together with in vivo cAMP and twitching phenotypes of key ChpA phosphorylation site po
228 t but weak correlation between MRC score and twitch pressure (rho = 0.26; P = 0.03) and TFdi (rho = 0
229 o the Ca2+ regulatory mechanism by analyzing twitch records measured in transgenic mice expressing a
233 es not influence 5-HT2 receptor induced head twitch response or impulsivity in a serial reaction time
234 vioral alterations, including increased head-twitch response to the hallucinogenic 5-HT(2A) agonist D
236 rol, in which phase-independent summation of twitch responses produces varying amounts of force deliv
237 ee discharges that cause massive involuntary twitch, revealing the prey's location and eliciting the
240 ynamic range and linear response properties, Twitch sensors represent versatile tools for neuroscienc
243 yosin light chain 1 between cardiac and slow-twitch skeletal muscle and establish Prox1 ablation as s
245 irect transcriptional repression of the fast-twitch skeletal muscle genes troponin T3, troponin I2, a
246 clearly observed between the hearts and slow-twitch skeletal muscle, suggesting that MYL2 mutated mod
250 tch extensor digitorum longus (EDL) and slow-twitch soleus (SOL) muscles derived from Sprague-Dawley
254 phorylation profile of sMyBP-C in mouse slow-twitch soleus muscle isolated from fatigued or non-fatig
256 and in contractile force (30%) in adult slow twitch soleus muscles (SOL) with no effect on fast twitc
260 el, which allowed us to predict responses to twitch stimulation in physiological conditions with the
261 ing mechanism, generating an average maximum twitch stress of 660 muN/mm(2) at Lmax, approaching valu
262 rientation within the scaffold affected peak twitch stress, demonstrating its ability to guide cells
263 enhancing the force produced by posttetanic twitches, structurally explaining posttetanic potentiati
264 D With Transfusions Changing to Hydroxyurea (TWiTCH) study and suggest that it may be safe to careful
265 They are involved in bacterial motility (twitching), surface adhesion, biofilm formation and DNA
268 half-maximal stress: 11 +/- 1 ms) and a high twitch/tetanus ratio (0.91 +/- 0.05), indicating adaptat
271 e spontaneous activity - in the form of limb twitches - that occurs exclusively and abundantly during
272 twitch followed immediately by an antagonist twitch-that developed postnatally in wild-types/heterozy
273 ik model" that emphasizes an accurate single-twitch time course and uses frequency-dependent modulati
274 t-exercise changes in potentiated quadriceps twitch torque (DeltaQTsingle ) evoked by electrical femo
275 V, diaphragm dysfunction was evaluated using twitch tracheal pressure in response to bilateral anteri
276 trans-diaphragmatic and esophageal pressure, twitch trans-diaphragmatic pressure (Tw Pdi), age, and m
277 in this setting is unknown; we performed the TWiTCH trial to compare hydroxyurea with standard transf
278 twitching [9-11], this finding suggests that twitches trigger the monosynaptic stretch reflex and, by
280 pitulate movement signatures associated with twitching: Two TFP can already produce movements reminis
281 fast-twitch type 2 fibres and increased slow-twitch type 1 fibres, together with a glycolytic-to-oxid
282 nt of skeletal muscle including loss of fast-twitch type 2 fibres and increased slow-twitch type 1 fi
283 tic fast-twitch (type IIb) to oxidative slow-twitch (type I) and intermediate (type IIa) fibers, an e
284 uscle fiber-type switch from glycolytic fast-twitch (type IIb) to oxidative slow-twitch (type I) and
285 l regulated kinases 1 and 2 (ERK1/2) in slow-twitch, type 1 skeletal muscle fibers, we studied the so
287 ped an automated method that can detect head twitches unambiguously, without relying on features in t
289 hesis that accounts for this paradox is that twitches, uniquely among self-generated movements, lack
290 position and predominantly in secondary fast-twitch units (m, ms) with increasing likelihood based on
294 In muscles, we found that the initiation of twitching was associated with a spreading calcium wave i
295 I "red" slow twitch and type II "white" fast twitch, which display marked differences in contraction
296 and vertical deflections of the nose, i.e., twitches, which are driven by activation of the deflecto
300 undamental understanding about how bacterial twitching would be affected by bacteria associated prope