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1 re BARC type 3a bleeds with 12 fatal bleeds (type 5).
2 r HIV entry coreceptor CC chemokine receptor type 5.
3 ted by species C human adenoviruses, such as type 5.
4 ases (ZFNs) targeting C-C chemokine receptor type 5.
5 48 h postinfection as compared to adenovirus type 5.
6 otein 4.2, leads to hereditary spherocytosis type 5.
7 ions, improve the storage time of adenovirus type 5.
14 nthesis of functionalized alkyne oxazoles of type 5; (2) intramolecular Diels-Alder/retro-Diels-Alder
16 mproved survival in patients with c-MET wild-type (5.7 v 3.6 months; P = .09) regardless of treatment
17 ORs and 95% CIs for overall beta-HPV and HPV types 5, 8, 15, 17, 20, 24, 36, and 38 association with
19 in (TLCN, or intercellular adhesion molecule type 5), a protein associated with maturation of dendrit
20 ells express CXCR5 (C-X-C chemokine receptor type 5, a chemokine receptor required for homing to GCs)
21 spectrin give rise to spinocerebellar ataxia type 5, a neurodegenerative disease characterized by pro
22 neutralization and persistence of adenovirus type 5, a prevalent nonenveloped human virus, are depend
23 recent studies show that spastic paraplegia type 5, a progressive neuropathy, is caused by loss-of-f
24 e small Rep proteins, adeno-associated virus type 5 (AAV5) generates a Rep40-like protein by alternat
25 ns is appended to the adeno-associated virus type 5 (AAV5) helicase domain, the resulting protein for
26 of de novo-generated adeno-associated virus type 5 (AAV5) Rep52 and capsid proteins is part of the l
29 We now show that mAKAPbeta selectively binds type 5 AC in the heart and that mAKAPbeta-associated AC
33 isation was prestratified by sex, adenovirus type 5 (Ad5) antibody titre at baseline, and study site.
34 The E1b55K and E4orf6 proteins of adenovirus type 5 (Ad5) assemble into a complex together with cellu
35 were polyubiquitinated during AAV-adenovirus type 5 (Ad5) coinfection and during transient transfecti
36 ether mutations in regions of the adenovirus type 5 (Ad5) DNA polymerase that interact with the dNTP
37 osis induced by infection with an adenovirus type 5 (Ad5) E1B 19-kilodalton (E1B 19K) gene deletion m
42 Results from Merck's phase II adenovirus type 5 (Ad5) gag/pol/nef test-of-concept trial showed th
44 proteins expressed from the E4 region of Ad type 5 (Ad5) inactivate the MRN complex by degradation a
46 OS are produced within minutes of adenovirus type 5 (Ad5) infection of macrophages and that oxidative
48 sociates with L4P and that during adenovirus type 5 (Ad5) infection, this association peaks at 12 h p
53 vel decreased significantly to 30% of the Ad type 5 (Ad5) mRNA level as measured by quantitative reve
57 rmined the structure of the human adenovirus type 5 (Ad5) to 3.6-A resolution and have reported the f
58 ck when an HIV-1 vaccine using an adenovirus type 5 (Ad5) vector failed to reduce, and might even hav
60 zed trial to determine whether an adenovirus type 5 (Ad5) vector vaccine, which elicits T cell immuni
61 inant replication-defective human adenovirus type 5 (Ad5) vector, Ad5-boIFN-lambda3, exhibited antivi
63 ignificantly in cells infected by adenovirus type 5 (Ad5), but not in those infected by the E1B 55-kD
64 vesicular stomatitis virus (VSV), adenovirus type 5 (Ad5), rhesus monkey rhadinovirus (RRV), and DNA
67 vaccine with a booster dose of an adenovirus type 5 (Ad5)-vectored vaccine, or (3) a 3-dose regimen o
70 g a newly constructed recombinant adenovirus type-5 (Ad5) that expresses enhanced jellyfish green flu
71 ministered through a replication incompetent type 5 adenovirus (Ad.mda-7) or with His-MDA-7/IL-24 pro
74 sly showed that AKAP79/150 clusters PKA with type 5 adenylyl cyclase (AC5) to assemble a negative fee
76 mer (Galpha(s) x betagamma) and the effector type 5 adenylyl cyclase (AC5), localized by the N termin
78 zed monoclonal IgG1 against human adenovirus type 5 (AdV5) and a panel of Fc-engineered variants with
79 tion material selective for human adenovirus type 5 (AdV5) offered highly purified virus for the subs
81 n 4 (CD4) and coreceptors chemokine receptor type 5 and chemokine-related receptor type 4 (CCR5 and C
82 e improved the structure of human adenovirus type 5 and confirmed our previous models of cement prote
83 Our data suggest that spinocerebellar ataxia Type 5 and spectrin-associated autosomal recessive cereb
85 currence of linked (L-type) and separated (S-type) 5S and 35S rDNA units, chromosome number, genome s
86 minor losses in affinity, Kd(mutant)/Kd(wild-type) = 5 and (ii) those where the apparent Kd was 50-
87 l cord when compared to the brain, while MOL types 5 and 6 (MOL5/6) increase their contribution to th
90 cted with HPV genus beta-species 1 (includes types 5 and 8), than BCC samples (P=0.01); this differen
91 eport relative abundances of all lengths and types (5' and 3') of single-stranded overhangs, if prese
92 pression and replication by human adenovirus type 5, and dysregulates cellular glucose and lipid meta
93 generative syndromes, spinocerebellar ataxia Type 5, and spectrin-associated autosomal recessive cere
94 hmogenic cardiomyopathy/ARVC subtype is ARVC type 5 (ARVC5), caused by a p.S358L mutation in TMEM43 (
95 llowed by a replication-deficient adenovirus type 5 boost (10(10) particle units) encoding all DNA va
96 ficacy of a DNA prime-recombinant adenovirus type 5 boost (DNA/rAd5) vaccine regimen in persons at in
98 mulus, suggesting that Distal Arthrogryposis Type 5 can be caused by gain-of-function mutations in PI
100 dular synthesis of the Staphylococcus aureus type 5 capsular polysaccharide repeating unit, a trisacc
101 -kDa protein-null mutant of human adenovirus type 5 carry a large number of posttranslational modific
102 were transduced with recombinant adenovirus type 5 carrying mouse Elovl4 and supplemented with 24:0,
103 and types 2 (CCL2), and C-C chemokine ligand types 5 (CCL5) in patients with alcoholic hepatitis.
105 r pleiotropic signaling of the C-C chemokine type 5 (CCR5) G protein-coupled receptor (GPCR) by predi
106 tor type 2 (Ccr2) and C-C chemokine receptor type 5 (Ccr5) in the livers of patients with ALD, and in
108 P < .001), and plasma CC chemokine receptor type 5 (CCR5) ligand (macrophage-inflammatory protein 1b
109 that ORM1 can bind to C-C chemokine receptor type 5 (CCR5) on muscle cells and deletion of the recept
111 lenge levels of CD4(+)C-C chemokine receptor type 5 (CCR5)(+)HLA-DR(+) T cells in the rectal biopsies
112 ein-coupled receptor, C-C chemokine receptor type 5 (CCR5), in human disease since ancient times.
113 equencies of foreskin C-C chemokine receptor type 5(+) (CCR5(+)) T cells, T regulatory cells, and T-h
114 ent without fast-inactivating component; and type 5 cells, with a large outward rectifying current wi
115 l is a potent and selective inhibitor of the type 5 cGMP (cyclic guanosine 3',5'-monophosphate)-speci
116 ents with a subtype of Distal Arthrogryposis Type 5 characterized by generalized autosomal dominant c
117 with replication-deficient human adenovirus type 5 constructs and boosting with ex vivo plasmid-tran
118 s and replication-deficient human adenovirus type 5 constructs encoding large sections of canine SMCY
124 (4) genome coverage by the different domain types, (5) degree of fit to a power-law distribution, (6
125 n with influenza B virus or human adenovirus type 5 did not induce significant levels of reporter exp
126 ain (conserved region 3 [CR3]) of adenovirus type 5 E1A (Ad5E1A) and requires the integrity of the en
127 In contrast, the nontumorigenic adenovirus type 5 E1A protein (E1A-5) and other E1A-12 mutants lack
128 s studies have indicated that the adenovirus type 5 E1B 55-kDa protein facilitates viral DNA synthesi
129 the mechanism by which the human adenovirus type 5 E1B 55-kDa protein protects against the antiviral
130 d target specificity displayed by adenovirus type 5 E4Orf6-E1B-55k as part of a cullin 5-containing E
132 f intraocular adenovirus-induced (adenovirus type 5 early region 1 [Ad5E1]) tumors in C57BL/6 mice.
133 ocular adenovirus-induced (Ad5E1; adenovirus type 5 early region 1) tumors are rejected in syngeneic
134 ng unit of S. aureus capsular polysaccharide type 5 equipped with capping methyl groups at the points
135 (60.7 +/- 6.3%), increased phosphodiesterase type 5 expression (167 +/- 13.7%) and decreased nitric o
137 Familial hemophagocytic lymphohistiocytosis type 5 (FHL5) is caused by defects in the Munc18b/STXBP2
139 macromolecular complexes with two subunits: type 5 G protein beta (Gbeta5) and R7 binding protein (R
142 complex with the short splice isoform of the type 5 G-protein beta subunit (G beta 5) and the RGS9 an
143 tic development ensures expression of RGS9-2/type 5 G-protein beta subunit/R7BP complexes at postsyna
144 ls homozygous for the C-C chemokine receptor type 5 gene with 32-bp deletions (CCR5Delta32) are resis
145 n hemoglobin beta and C-C chemokine receptor type 5 genes have substantial off-target cleavage, espec
148 ptotic gene PUMA to FLS via human adenovirus type 5 (HAdV5) vectors has been tested as a therapeutic
149 familial hemophagocytic lymphohistiocytosis type 5 has identified the E132A mutation in the hydropho
150 ere given a replication-defective adenovirus type 5 HIV-1 gag vaccine in a randomized, blinded therap
151 nimals immunized with replicating adenovirus type 5 host range (Ad5hr) recombinant viruses expressing
152 t with replication-competent adenovirus (Ad) type 5 host range mutant (Ad5 h) expressing SIV gag and
153 ollowing priming with replicating adenovirus type 5 host range mutant (Ad5hr)-human immunodeficiency
154 osally with replication-competent adenovirus type 5 host range mutant (Ad5hr)-simian immunodeficiency
155 lly primed twice with replicating adenovirus type 5 host range mutant (Ad5hr)-SIV recombinants and sy
156 riming with replication-competent adenovirus type 5 host range mutant (Ad5hr)-SIV recombinants, follo
158 shown that sequential replicating adenovirus type 5 host range mutant human immunodeficiency virus/si
159 twice mucosally with replicating adenovirus type 5 host range mutant SIV env/rev, gag, and nef recom
161 nicamycin treatment of cells expressing wild-type 5-HT(2A)R resulted in an altered electrophoretic mo
162 12A) mutant, when co-expressed with the wild-type 5-HT(3)A subunit, did not affect functional express
163 y coexpression of the membrane-tethered wild-type 5-HT2B receptor N terminus was not observed using a
164 Furthermore, by coexpressing a tethered wild-type 5-HT2B receptor N terminus with a 5-HT2B receptor b
165 II (CRABP-II) and fatty acid binding protein type 5 in adipocytes and skeletal muscle, leading to enh
166 we have examined the L4P of human adenovirus type 5 in detail and have defined its transcription star
168 es to evaluate the role of phosphodiesterase type 5 inhibition as adjunctive medical therapy in patie
169 r been ascertained whether phosphodiesterase type 5 inhibition exerts an antiremodeling effect in non
170 e overload have shown that phosphodiesterase type 5 inhibition is beneficial; however, the use of pho
172 yl-1-methylxanthine (IBMX; phosphodiesterase type 5 inhibitor and adenosine antagonist, 10 micromol/L
173 me that a single dose of a phosphodiesterase type 5 inhibitor is safe and well tolerated in patients
174 both nitric oxide and the phosphodiesterase type 5 inhibitor sildenafil in carefully selected patien
177 properties of a selective phosphodiesterase type 5 inhibitor, sildenafil, in a model of diabetic car
180 icial; however, the use of phosphodiesterase type 5 inhibitors in patients with aortic stenosis is co
181 potential clinical use of phosphodiesterase type 5 inhibitors in patients with coexisting LUTS and e
182 In men, medication such as phosphodiesterase type 5 inhibitors may be beneficial, and surgery remains
183 that sildenafil and other phosphodiesterase type 5 inhibitors may enhance the sensitivity of certain
184 lin receptor antagonist or phosphodiesterase type 5 inhibitors were continued in 15/27 patients (55%)
186 ylate cyclase stimulators, phosphodiesterase type 5 inhibitors, sodium nitrite and endothelin recepto
191 ct of cataract surgery and phosphodiesterase type-5 inhibitors remains to be further studied on a lar
195 potential of a novel lipopeptide/adenovirus type 5 (Lipo/rAdv5) prime/boost mucosal vaccine for indu
197 ainfluenza virus type 2, parainfluenza virus type 5, measles virus, mumps virus, Hendra virus, and Ni
200 excitatory synaptic transmission mediated by type 5 metabotropic glutamate (mGlu5) receptors was enha
201 oduces antinociception in rats by activating type 5 metabotropic glutamate receptors (mGlu(5)) in the
203 The anomalous synaptic plasticity requires type 5 metabotropic glutamate receptors (mGluR5s), which
204 the authors investigated the effects of the Type-5 metabotropic glutamate receptors (mGluR5) positiv
205 ged derivative of the metabotropic glutamate type 5 (mGlu5) receptor negative allosteric modulator ra
206 e we show that D1 and metabotropic glutamate type 5 (mGlu5) receptors can form previously unknown het
207 lly blocking metabotropic glutamate receptor type 5 (mGluR5) activation in IL during extinction train
208 eductions in metabotropic glutamate receptor type 5 (mGluR5) binding in smokers and recent ex-smokers
209 decrease in metabotropic glutamate receptor type 5 (mGluR5) expression and reduced glutamate turnove
210 ctivation of metabotropic glutamate receptor type 5 (mGluR5) on interneuron spines leads to local GAB
211 ntagonist of metabotropic glutamate receptor type 5 (mGluR5) or its downstream signaling molecules (P
212 ctivation of metabotropic glutamate receptor type 5 (mGluR5) signaling and that this astrocyte-mediat
213 ligands for metabotropic glutamate receptor, type 5 (mGluR5), is essential to measure changes in brai
216 no pathogenic mutations in BRAF or KRAS), or type 5 (MSI-high, no CIMP, no pathogenic mutations in BR
217 egative for mutations in BRAF and KRAS); and type 5 (MSI-high, non-CIMP, negative for mutations in BR
219 igand 5 that binds to C-C chemokine receptor type 5 on BCCs and BCCs secrete cytokine CSF1 that binds
220 K9) encodes the protein ATP13A2, a lysosomal type 5 P-type ATPase that is linked to autosomal recessi
222 in hexon; and noninfectious human adenovirus type 5 particles assembled in the absence of VII (Ad5-VI
223 tase, proprotein convertase subtilisin/kexin type 5 (PCSK5), causing inactive GDF11 precursor to accu
224 urin, proprotein convertase subtilisin/kexin type 5 (PCSK5), paired amino acid converting enzyme-4 (P
225 gnizing that inhibitors of phosphodiesterase type 5 (PDE5) are increasingly employed in patients with
226 ence suggests that reduced phosphodiesterase type 5 (PDE5) expression increases the invasiveness of m
228 ne monophosphate-selective phosphodiesterase type 5 (PDE5) influences maladaptive remodeling in heart
230 ports an evolving role for phosphodiesterase type 5 (PDE5) inhibition in patients with pulmonary hype
232 he effect of Sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor, on nestin lineage neural stem c
233 rectile dysfunction drugs, phosphodiesterase type 5 (PDE5) inhibitors, is part of a pathway implicate
234 he cGMP-hydrolyzing enzyme phosphodiesterase type 5 (PDE5) might exert renoprotective effects in DN.
235 ophosphate (cGMP) specific phosphodiesterase type 5 (PDE5) plays an important role in various patholo
236 arkably similar to that of phosphodiesterase type 5 (PDE5), an enzyme that catalyzes the hydrolysis o
237 New York, NY), a selective phosphodiesterase type-5 (PDE5) inhibitor, is widely used to treat impoten
238 first randomized placebo-controlled trial of type-5 phosphodiesterase therapy in treatment-naive chil
239 aling molecules, including phosphodiesterase type 5, phosphorylated endothelial nitric oxide synthase
240 (IFN) alpha/beta against parainfluenza virus type 5 (PIV5), selectively inhibiting the translation of
241 in which the V protein of parainfluenzavirus type 5 (PIV5; formerly known as simian virus type 5 [SV5
242 genes, Legionella pneumophila, or adenovirus type 5, promoted a marked induction of IFN-beta mRNA exp
244 hat protein tyrosine phosphatase nonreceptor type 5 (PTPN5) (also known as STEP) is a critical determ
245 Protein tyrosine phosphatase non-receptor type 5 (PTPN5, STEP) is a brain specific phosphatase tha
246 prime vaccine, with a recombinant adenovirus type 5 (rAd5) boost, failed to protect from HIV-1 acquis
247 A priming followed by recombinant adenovirus type 5 (rAd5) boosting elicited CD8(+) T-cell-mediated a
248 egimens revealed that recombinant adenovirus type 5 (rAd5) prime followed by replication-defective ly
249 elope (Env) DNA/recombinant adenovirus virus type 5 (rAd5) vaccine studied in HIV-1 Vaccine Trials Ne
250 accine delivered with recombinant adenovirus type 5 (rAd5) vectors showed no efficacy in lowering vir
252 cine trial (DNA prime/recombinant adenovirus type 5 [rAd5] boost) (VRC-10-332) that demonstrated subs
255 ation activity relieves repression of oocyte-type 5 S rRNA genes and is correlated with a decrease in
256 repressor complex exclusively to the oocyte-type 5 S rRNA genes, leading to their terminal repressio
257 are present on oocyte-type, but not somatic-type, 5 S rRNA genes up through the neurula stage, as is
259 ion (L253P) linked to spinocerebellar ataxia type 5 (SCA5) causes a dramatic increase in actin bindin
265 ink strongly to human spinocerebellar ataxia type 5 (SCA5), correlating with alterations in EAAT4.
266 linical phenotypes of spinocerebellar ataxia type-5 (SCA5) and spectrin-associated autosomal recessiv
267 logical diseases, hereditary spastic paresis type 5 (SPG5) and cerebrotendinous xanthomatosis (CTX),
269 ions in the serine peptidase inhibitor Kazal type 5 (SPINK5) skin barrier gene have previously been a
270 ggrin (FLG), serine protease inhibitor Kazal-type 5 (SPINK5), and thymic stromal lymphopoietin (TSLP)
272 cus sequence typing (MLST) revealed sequence type 5 (ST5) (n = 2), ST6 (n = 3), and ST185 (n = 1), wh
275 MRSA (HA-MRSA) genotype (multilocus sequence type 5 [ST5] or SCCmec type II), the majority of mupA-po
276 type 5 (PIV5; formerly known as simian virus type 5 [SV5]) interacts with LGP2 and cooperatively inhi
277 ic deficiency of CC-chemokine receptor (CCR) type 5, the common receptor of chemokine (C-C motif) lig
278 esigned a replication-incompetent adenovirus type 5 to deliver a LANA-specific Cas9 system (Ad-CC9-LA
280 The transient receptor potential vanilloid type 5 (TRPV5) Ca(2+) channel facilitates transcellular
287 intramuscular prime/boost with an adenovirus type 5 vector induced a higher level of systemic CD8+ T
289 We recently showed that clearance of Ad type 5 vectors by KCs does not involve the interaction o
290 inia virus Ankara) and Ad5 (human adenovirus type 5) vectors both expressing Ag85A in a single vaccin
292 interneurons were subjected to a 3 day binge-type 5% w/w ethanol consumption regimen from embryonic d
294 inhibitor of cGMP-specific phosphodiesterase type 5, was found to significantly reverse ABC-transport
296 e nine known promoters from human adenovirus type 5 were analyzed for inherent DNA softness using the
297 ding beta-III spectrin (SPTBN2) underlie SCA type-5 whereas homozygous mutations cause spectrin assoc
298 ry artery bypass grafting (CABG)-related MI (type 5), which are of uncertain prognostic importance.
299 taphylococcus aureus capsular polysaccharide type 5, which is also a potential antigen for immunother
300 ctivation muscarinic acetylcholine receptors type 5, which mediate potentiation of dopamine transmiss