ライフサイエンスコーパス: type I collagen

1 al propeptide, and C-terminal telopeptide of type I collagen).

2 usable vessels in a bioremodelable hydrogel (type I collagen).

3 anslation of collagen mRNAs and synthesis of type I collagen.

4 lity and in vitro proteolytic degradation of type I collagen.

5 ly349Cys substitution in the alpha1 chain of type I collagen.

6 s by secreting mesenchymal proteins, such as type I collagen.

7 nectin (FN) and block interaction of FN with type I collagen.

8 synthesis, and facilitating cell adhesion to type I collagen.

9 er GFP mice, we find that fibrocytes express type I collagen.

10 hat fibrocytes are not a necessary source of type I collagen.

11 re required for efficient internalization of type I collagen.

12 NF-alpha), RAGE, periostin, fibronectin, and type I collagen.

13 ars of age stimulates fibroblasts to produce type I collagen.

14 tin, SNAIL1, SNAIL2, and the alpha2 chain of type I collagen.

15 ion of Syk activity restored MK migration on type I collagen.

16 e the production and spatial organization of type I collagen.

17 ast tumor cell line, MDA-MB-231, embedded in type I collagen.

18 cifically inhibits their capacity to degrade type I collagen.

19 ration and reduced accumulation of fibrillar type I collagen.

20 pancreatic cancer cells in three-dimensional type I collagen.

21 matrix via the upregulation of the gene for Type I Collagen.

22 profile of 3D tissues embedded within native type I collagen.

23 d the LH3 function as glucosyltransferase in type I collagen.

24 nM concentrations of C9 reduced secretion of type I collagen.

25 cancer cell scattering in three-dimensional type I collagen.

26 ilize integrins to attach and proliferate on type I collagen.

27 is characterized by excessive production of type I collagen.

28 l fibroblasts led to increased expression of type I collagen.

29 serum beta C-terminal telopeptide (B-CTx) of type I collagen.

30 cise co-localization of CNA-35 micelles with type I collagen.

31 otype resulted in a significant reduction of type I collagen.

32 p.G736D) substitution in the alpha1 chain of type I collagen.

33 h Fam20C was inactivated in cells expressing Type I collagen.

34 FKBP19 seems to interact with triple helical type I collagen.

35 and was further increased after adhesion to type I collagen.

36 5 prefers to interact with Hsp47 rather than type I collagen.

37 nsistent with decreased proband secretion of type I collagen.

38 alities in the structure and/or synthesis of type I collagen.

39 s or solid spiky masses when plated in 3D in type-I collagen.

40 e, where little 3-hydroxylation was found in type I collagen, 3-hydroxylation of type I collagen in a

41 inary N-terminal cross-linked telopeptide of type I collagen: 48.2 +/- 2.9 compared with 38.9 +/- 0.9

42 Our data reveal that type I collagen accumulation in shear-activated PTECs is

43 ail1, Twist1, alpha-smooth muscle actin, and type I collagen accumulation.

44 of PDL osteoblastic differentiation markers: type I collagen, alkaline phosphatase, and osteocalcin.

45 , the multilayered cells express Osterix and Type I collagen alpha, resulting in generation of mature

46 ver, mature osteoblast-related expression of type I collagen alpha1 and osteocalcin was reduced in bo

47 pproximately 90% direct sequence coverage of type I collagen alpha1- and alpha2-chains, representing

48 chondral bone were determined by MicroCT and type I collagen alpha1/alpha2 ratio was determined by SD

49 lant with recombinant resistin increased the Type I collagen alpha1/alpha2 ratio.

50 ce/bone volume ratio, and an increase in the Type I collagen alpha1/alpha2, compared to normal-weight

51 f intron 36 of the Col1a1 gene, encoding the type I collagen, alpha1 chain, was responsible for the p

52 nt groups using a biopsy-based evaluation of type I collagen alphaI (col1a1) levels.

53 tegrin beta1 (ITGB1) subunits, as well as by type I collagen (an integrin alpha2beta1 ligand).

54 0 secretion increased by 90% with binding to type I collagen and 55% with fibronectin, whereas MMP-7

55 hesion to and aggregation induced by soluble type I collagen and a delayed onset to low dose fibrilla

56 gh levels of type II collagen as compared to type I collagen and absence of Mmp-9 in the cartilage of

57 Recombinant human relaxin-2 down-regulates type I collagen and alpha smooth muscle actin production

58 19b was confirmed by decreased expression of type I collagen and by blocking TGF-beta-induced express

59 gen biosynthesis, which retards secretion of type I collagen and causes excessive posttranslational m

60 rkably long half-life, matrix proteins, like type I collagen and elastin, are preferential targets.

61 Adhesion to type I collagen and fibronectin by Mycobacterium tubercu

62 em mass spectrometry) showed increased renal type I collagen and fibronectin protein abundance result

63 extracellular matrix proteins, specifically type I collagen and fibronectin.

64 ockdown had impaired TGF-beta stimulation of type I collagen and fibronectin.

65 deposition was accelerated with upregulated type I collagen and interleukin-1beta, and downregulated

66 1), (2) significantly promoted production of type I collagen and other extracellular molecules (p < 0

67 re characterized by the expression of alpha1 type I collagen and PDGFRbeta, produce erythropoietin th

68 Channel catfish skin collagens were typical type I collagens and could have applications in food, me

69 gulation of its downstream ECM genes such as type I collagens and proteoglycans such as fibromodulin

70 em, we provide evidence that TRIP-1 binds to Type-I collagen and can promote mineralization.

71 Tissues from sclera and cornea (type I collagen) and lens capsule (type IV collagen) wer

72 PINP, PIIINP, and C-terminal telopeptide of type I collagen) and right heart catheterization.

73 CTX (C-terminal crosslinking telopeptide of type I collagen) and TRACP-5b (tartrate-resistant acid p

74 lagen type I, carboxyterminal telopeptide of type I collagen, and aminoterminal propeptide of procoll

75 up-regulation of alpha-smooth muscle actin, type I collagen, and fibronectin expression.

76 scular endothelial growth factor, periostin, Type I collagen, and fibronectin were also evaluated.

77 They also exhibited increased adhesion on type I collagen, and hyperresponsive CRP and CLEC-2-indu

78 rgely suppressed expression of alpha-SMA and type I collagen, and reduced the deposition of extracell

79 rosine-phosphorylated proteins and levels of type I collagen, and scavenged ROS in SSc fibroblasts.

80 a1 integrin in contact with dermal fibrillar type I collagen, and the activity of MMP-1 is required f

81 on of alpha-smooth muscle actin (alpha-SMA), type I collagen, and VE-cadherin expression, and the exp

82 Fibrils of type I collagen are formed by the packing of polypeptide

83 g the expression of Bcl-xL, whereas those on type I collagen are not.

84 ll surface HA coat impaired cell adhesion to type I collagen, as indicated by recovery of adhesion fo

85 Type-I collagen assembles in a stepwise, hierarchic fash

86 s suggest that amide I NLO chiral effects in type I collagen assemblies arise predominantly from the

87 ight into how LECs negotiate an interstitial type I collagen barrier and reveal an unexpected MMP2-dr

88 Fibrillar type I collagen-based hydrogels are commonly used in tis

89 her levels of carboxyterminal telopeptide of type I collagen (beta=0.22, P<0.001) and aminoterminal p

90 f the alpha2beta1 integrin, one of the major type I collagen-binding receptors in mammalian cells.

91 and alphaVbeta3 blockade markedly decreased type I collagen breakdown, and impaired both monocyte ad

92 dominant bone dysplasia caused by defects in type I collagen, but in the past 10 years discoveries of

93 g growth factor beta1-mediated expression of type I collagen by inhibiting Twist, a prominent mesench

94 ose dependently inhibited the degradation of type I collagen by P. gingivalis.

95 sidues/1000 residues) and were identified as type-I collagens by FTIR, SDS-PAGE, and molecular weight

96 Finally, absence of the type I collagen C-propeptidase bone morphogenetic protei

97 e sex, high levels of bone resorption (serum type I collagen C-telopeptide), low hip bone mineral den

98 The included characteristics sex, serum type I collagen C-telopeptide, hip bone mineral density,

99 Matrix metalloprotease (MMP)-degraded type I collagen (C1M), type III collagen (C3M), type IV

100 Excessive deposition of type I collagen causes fibrotic diseases.

101 cid compositions of rat skin and tail tendon type I collagen chains indeed showed 3-4 residues of 3Hy

102 droxylation at multiple substrate sites from type I collagen chains was high in sclera, similar to te

103 del using culture plate wells connected with type I collagen-coated large bore tubing and has recircu

104 neralized tissue-associated genes, including Type I collagen (COL I), runt-related transcription fact

105 Recent studies indicate that type I collagen (COL) is important in the development of

106 Raman spectra from as-prepared type I collagen (Col-I) and Ag-NP-coated Col-I fibers on

107 eta1, tumor necrosis factor (TNF)-alpha, and type I collagen (Col-I) expression, and promoted the pro

108 reporter protein (EGFP) under control of the type I collagen (Col-I) promoter (COL-EGFP) had green st

109 MC), resulted in increased protein levels of type I collagen (Col-I).

110 r characterized by the impaired synthesis of type I collagen (Col1).

111 ultures of mouse hepatocytes were exposed to type I collagen (COL1); cell injury was assessed by morp

112 ic factors Alpha-Actin-2 (ACTA2) and Alpha-1 Type I Collagen (COL1A1) in HSCs.

113 scence reporter downstream of the endogenous type I collagen (COL1A1) promoter in skin fibroblasts.

114 r matrix (ECM) proteins fibronectin (FN) and type I collagen (collagen I) are codistributed in many t

115 th altered subchondral bone architecture and type I collagen composition.

116 Type I collagen-containing fibrils are major structural

117 scratch wound assay, cell number count, and type I collagen contraction assay were used to examine t

118 onger detectable, but the structural protein type I collagen could be used to differentiate all four

119 SDS-PAGE was performed on type I collagen cross-linked in the absence and presence

120 Outcome measures were type I collagen crosslinked beta C-telopeptide (betaCTX)

121 P) and C-terminal crosslinked telopeptide of type I collagen (CTX) derived from matrix-metalloprotein

122 increase in serum C-terminal telopeptide of type I collagen (CTX) was completely reversed by ES.

123 bone resorption (C-terminal telopeptides of type I collagen (CTX)) and bone formation (procollagen t

124 resorption marker C-telopeptide fragments of type I collagen (CTX), elevated osteoclastogenesis, and

125 the bone resorption marker C-telopeptide of type I collagen (CTX-1) were observed.

126 pe I procollagen (PINP) and C-telopeptide of type I collagen (CTX-I) are markers of bone formation an

127 Production of type I collagen declines during aging, leading to skin t

128 ere most cases are due to autosomal dominant type I collagen defects, while rare, mostly recessive, f

129 findings provide a mechanistic paradigm for type I collagen degradation by MMP1 and establish a gene

130 both of which are associated with increased type I collagen density and tissue stiffness and are the

131 feeding while giving rise to adipocytes and type I collagen-depositing fibroblasts.

132 oposed as an important direct contributor of type I collagen deposition during fibrosis based largely

133 increased glycosylation of hydroxylysine in type I collagen disturbs the lateral growth of the fibri

134 How structural mutations of type I collagen (dominant OI) or of its post-translation

135 inding sequence could lead to degradation of type I collagen, early embryonic lethality, and the scar

136 ) and Ser(203) in MFAP4 as being crucial for type I collagen, elastin, and tropoelastin binding.

137 Further, type I collagen enhanced the motility of Braf(V600E)/Pte

138 ion and cell invasion in a three-dimensional type I collagen environment.

139 ng with a gadolinium-based probe targeted to type I collagen (EP-3533) to image and quantify fibrosis

140 actor beta1 (TGFbeta1) induced alpha-SMA and type I collagen expression and inhibited VE-cadherin.

141 r-kappaB (NF-kappaB) transcription factor on type I collagen expression in adult normal human (ANF) a

142 in-1) and Sp3, acting as trans-activators of type I collagen expression in ANF and SF.

143 -costimulated SSc lymphocytes induced higher type I collagen expression in fibroblasts, which was par

144 To assess the role of the stem-loop in type I collagen expression in vivo, we generated a knock

145 ia from TNFR-costimulated T lymphocytes, and type I collagen expression was quantified.

146 ype III collagen expression or a decrease in type I collagen expression were confirmed.

147 the cell line faithfully reports changes in type I collagen expression with at least threefold enhan

148 stimulation of alpha-smooth muscle actin and type I collagen expression, indicative of myofibroblast

149 n siRNAs for regulators of TGF-beta1-induced type I collagen expression.

150 their translation and is necessary for high type I collagen expression.

151 The fibrotic areas mainly consist of type I collagen extracellular matrix and, only to a less

152 onstrate that shortly following contact with type I collagen extracellular signal-regulated kinase (E

153 Type I collagen extracted from bone of P3H1 null mice sh

154 Type I collagen extracted from different tissues showed

155 of the A3 site in both alpha-chains, whereas type I collagen extracted from tendon of P3H1 null mice

156 Type I collagen extracted from tendon, skin, and bone of

157 r cells exposed to a physiological matrix of type I collagen fibers form elongated collagenolytic inv

158 Mouse tail type I collagen fibers were incubated with either catK o

159 ng as a fibronectin-independent mechanism of type I collagen fibrillogenesis following adult liver in

160 Here, we investigate type I collagen fibrillogenesis using confocal rheology-

161 Type I collagen fibrils are the primary components of te

162 erminal domains resulted in fragmentation of type I collagen fibrils in a three-dimensional collagen

163 Accumulation of type I collagen fibrils in tumors is associated with an

164 ng and radial nanoindentation, we found that type I collagen fibrils show a pronounced nonlinear beha

165 d by fragmentation and reduced production of type I collagen fibrils that provide strength to skin.

166 The ECM consists mostly of type I collagen fibrils, which are produced by fibroblas

167 ermal extracellular matrix with GAG bound to type I collagen fibrils.

168 lution tracking of individual MMPs degrading type I collagen fibrils.

169 train K279a also promoted the degradation of type I collagen, fibrinogen, and fibronectin in a predom

170 cell carcinoma stroma, CCN2-regulated genes type I collagen, fibronectin, and alpha-smooth muscle ac

171 g vascular endothelial growth factor (VEGF), type I collagen, fibronectin, and periostin.

172 nd from cholesteric liquid crystal-like (LC) type I collagen films.

173 molecules involved in tissue repair, such as type I collagen, FN, and periostin.

174 dings, Cyp2j4(-/-) rats show upregulation of type I collagen following unilateral ureter obstruction

175 alpha1alpha2alpha1, alpha2alpha1alpha1) of a type I collagen fragment (the binding region for the von

176 mation and release of C-terminal fragment of type I collagen from cells cultured on bone slices.

177 Type I collagen gels are routinely used in biophysical s

178 To do so, type I collagen gels or ECM extracted from apolipoprotei

179 transgenic system to specifically delete the type I collagen gene across a broad population of hemato

180 r, fibrocytes with confirmed deletion of the type I collagen gene have readily detectable intracellul

181 MRTF-A transactivated type I collagen gene reporters as much as 100-fold in lu

182 In contrast, in zebrafish three type I collagen genes exist, col1a1a, col1a1b and col1a2

183 Transcriptional mechanisms regulating type I collagen genes expression in physiopathological s

184 ave heterozygous mutations in one of the two type I collagen genes, COL1A1 and COL1A2.

185 t could benefit even those with mutations in type I collagen genes.

186 ls of alpha-smooth muscle actin (alpha-SMA), type I collagen, heat shock protein-47 (HSP-47), fibrone

187 oreover, TGF-beta1 induced the production of type I collagen, HSP-47, FN, and periostin.

188 In vitro polymerized type I collagen hydrogels have been used extensively as

189 lysis identified five glycosylation sites in type I collagen (i.e. alpha1,2-87, alpha1,2-174, and alp

190 cross-linked carboxyterminal telopeptide of type I collagen (ICTP) and C-terminal crosslinked telope

191 N-terminal peptide], CITP [C-telopeptide for type I collagen], IGFBP7 [insulin-like growth factor-bin

192 inary N-terminal cross-linked telopeptide of type I collagen in a 1999-2002 subset with available dat

193 tate cancer cell adhesion to fibronectin and type I collagen in a FAK-dependent manner, correlating w

194 However, the biosynthesis of type I collagen in affected horse fibroblasts shows a de

195 found in type I collagen, 3-hydroxylation of type I collagen in affected horses is normal.

196 revealed tissue disorganization and reduced type I collagen in bgn(-/0)fmod(-/-) TMJ subchondral bon

197 Biosynthesis of type I collagen in fibrosis is augmented by binding of p

198 l vessel tissues, as well as the presence of type I collagen in the outermost vessel layers, using im

199 ent pericellular collagenase that can cleave type I collagen in vitro.

200 sponse demonstrated collagen-rich matrix (by type I collagen), incorporating the device components wi

201 n gene have readily detectable intracellular type I collagen indicating that uptake of collagen from

202 Fibrosis with excessive amounts of type I collagen is a hallmark of many solid tumours, and

203 Normal type I collagen is a heterotrimer triple-helical molecul

204 Type I collagen is a heterotrimeric extracellular matrix

205 Type I collagen is a key protein of most connective tiss

206 The A1 site (Pro-986) in the alpha1-chain of type I collagen is almost completely 3-hydroxylated in e

207 hese results demonstrate that the A1 site in type I collagen is exclusively 3-hydroxylated by P3H1, a

208 Fibrillar type I collagen is the major organic component in bone,

209 Type I collagen is the most abundant protein in the huma

210 Type I collagen is the predominant collagen in mature te

211 n that alpha2beta1 integrin, the receptor of type I collagen, is the major collagen-binding integrin

212 t inactivation of Fam20C in cells expressing type I collagen led to skeletal defects and hypophosphat

213 othelin-1, troponin I, and C-telopeptide for type I collagen levels, suggesting more severe neurohumo

214 ly 40% of SKPs were found to be derived from type I collagen-lineage cells and acquired multipotency

215 Consequently, WISP1-induced type I collagen linearization facilitates tumor cell inv

216 re plated within standard bovine or rat tail type I collagen matrices (2.5 mg/mL), compressed collage

217 Primary cultures of HGFs were grown on Type I collagen matrices previously treated with MGO.

218 ontrolling the microstructure and density of type I collagen matrices.

219 l as in modulating cellular invasion through type I collagen matrices.

220 eutics incorporated into the self-assembling type I collagen matrix described here can be delivered n

221 in cell expressing actin-eGFP cultured in a type I collagen matrix, the laser was orbited around the

222 oliferation, migration, and cell adhesion on type I collagen matrix.

223 ificant increase in the expression of alpha1 type I collagen, matrix metalloprotease-1, and platelet-

224 Sponges of bioabsorbable type I collagen membrane were exposed to papain based ge

225 IMP-2 and -3 transcript levels but inhibited type I collagen, MMP 1 and TIMP 1 mRNA levels.

226 To elucidate the function of LH3 in bone type I collagen modifications, we used a short hairpin R

227 occurs at the specific molecular loci in the type I collagen molecule and plays critical roles in con

228 ucture (5'SL), which is found exclusively in type I collagen mRNAs.

229 imperfecta (OI) is a bone disease caused by type I collagen mutations and characterized by bone frag

230 sociated with preservation of the myocardial type I collagen network as a consequence of the decrease

231 Organized type I collagen networks in TGF-betaIIR knockout livers

232 at the nonlinear stiffening of reconstituted type I collagen networks is controlled by the applied st

233 protectin, osteocalcin, and N-telopeptide of type I collagen (NTx) levels were analyzed by ELISA.

234 Moreover, the type I collagen of Crtap(-/-) mice shows reduced binding

235 py targeted at epithelial cell production of type I collagen offers a novel pathway for abrogating th

236 as to investigate the use of self-assembling type I collagen oligomers as an injectable therapeutic d

237 We study the mechanics of type I collagen on the scale of tens to hundreds of micr

238 ted adhesion of human platelets to monomeric type I collagen or to the GFOGER peptide caused a time-d

239 important protease responsible for degrading type I collagen, osteopontin, and other bone matrix prot

240 modification, we characterized and compared type I collagen phenotypes produced by Sh clones and two

241 Deletion of IFT80 in type I collagen-positive cells led to a disorganized out

242 onstrated that inhibition of DDR1 binding to type I collagen, preserving the engagement of the other

243 matic increase in the uncleaved precursor of type I collagen (procollagen I) and a reduction in denti

244 show by inducible genetic fate mapping that type I collagen-producing submesothelial fibroblasts are

245 indicate a TGF-beta-independent mechanism of type I collagen production and suggest connective tissue

246 le actin expression, F-actin expression, and type I collagen production in fibroblasts.

247 attenuated histamine-induced cell growth and type I collagen production.

248 Here, we show that hypoxia increases type I collagen prolyl-4-hydroxylase [C-P4H(I)], which l

249 Expression of the fibroblast markers type I collagen, prolyl-4-hydroxylase, fibroblast specif

250 As fibrillar type I collagen promotes pro-matrix metalloproteinase 2

251 as well as HSCs; intracellular and secreted type I collagen protein levels also decreased.

252 e bone matrix that is also distinct from the type I collagen-related form of OI.

253 via a four amino acid stretch (analogous to type I collagen residues 782-785).

254 ive carcinoma cells gain permanent access to type I collagen-rich interstitial tissues, an experiment

255 tures provide a new mechanism of adhesion to type I collagen-rich tissues that does not rely on hydro

256 However, type I collagen, RUNX2, type X collagen (CoL10A1), Oster

257 levels of Sox9, type II collagen, aggrecan, type I collagen, Runx2, type X collagen, ALP, Osterix, a

258 When a six-triplet human type I collagen sequence containing GFPGER was introduce

259 ns that is dominated by polymeric fibrils of type I collagen, serves as the mechanical scaffold on wh

260 bitor, b-AP15, reduced the expression of FN, type I collagen, Smad2/Smad3, and the deposition of coll

261 Type-I collagen suspensions demonstrated a strong, negat

262 IL-34-Mphi and M-CSF-Mphi induce type I collagen synthesis by HSCs, the main collagen-pro

263 l modifications of LARP6 and how they affect type I collagen synthesis have not been studied.

264 luble endoglin limits TGFbeta1 signaling and type I collagen synthesis in cardiac fibroblasts and fur

265 ultures to histamine favored cell growth and type I collagen synthesis via the activation of H1 recep

266 uses elongation of fibroblasts, coupled with type I collagen synthesis, which is dependent on the TGF

267 led to enhanced adhesion, proliferation, and type I collagen synthesis.

268 g matrix metalloproteinase 1 and suppressing type I collagen synthesis.

269 regulates cell survival, proliferation, and type I collagen synthesis.

270 These experiments revealed that type I collagen synthesized by mutant cells had decrease

271 n, metabolism, and pharmacokinetics of a new type I collagen-targeted magnetic resonance (MR) probe,

272 rstitial matrix mainly composed of fibrillar type I collagen, the interactions occurring between lymp

273 The synthesis of type I collagen, the main component of bone matrix, prec

274 Type I collagen, the primary fibrous ECM constituent, be

275 In addition to not binding to type I collagen, the R1R2.FN complex incorporated less e

276 olvement in the regulation of MK motility on type I collagen through a mechanism based on the activit

277 l contribution of hematopoietic cell-derived type I collagen to fibrogenesis, we use a double-transge

278 Specifically, WISP1 directly binds to type I collagen to promote its linearization in vitro (i

279 Previously, we showed that ER CRT regulates type I collagen transcript, trafficking, secretion, and

280 egulator of TGF-beta and potent inhibitor of type I collagen transcription.

281 Red-COLA1, as a new efficient tool to study type I collagen transcriptional regulation.

282 Given that ARCN1 deficiency causes defective type I collagen transport, reduction of collagen secreti

283 sential repeating tripeptide sequence of the type I collagen triple helix results in the dominant her

284 ger residue in the repeating sequence of the type I collagen triple helix, lead to the hereditary bon

285 collagen, and type X collagen, but not with type I collagen, type II collagen, or type V collagen.

286 On a larger scale, deformations in Type I collagen vary with a periodicity consistent with

287 Type I collagen, VEGF, and Cbfa1 were upregulated in the

288 s and dentin depends on the self-assembly of type I collagen via the Gly-X-Y motif, the molecular mec

289 NLO) chiral effects in the amide I region of type I collagen was investigated using sum-frequency gen

290 reduction in total hydrolysis of elastin and type I collagen was measured compared with computational

291 Furthermore, type I collagen was preserved from hydrolysis when a 10-

292 cross-linked carboxyterminal telopeptide of type I collagen were also significantly reduced in the C

293 st levels of carboxy-terminal telopeptide of type I collagen were observed in ZOL (P < 0.05), and sho

294 lasma cross-linked C-terminal telopeptide of type I collagen were reduced by >/= 50% in 57% of evalua

295 The homotrimeric isoform of type I collagen, which consists of three alpha-1 chains,

296 Human tarsal plate contains type I collagen, which is crosslinked in corneal tissue

297 rly osteogenic marker genes, ALP, Runx2, and type I collagen, which play a critical role in MSC to os

298 The fibrotic areas mainly consisted of type I collagen with only a minor cellular component (es

299 Ovarian cortex biopsies were embedded in type I collagen with or without VEGF111 addition before

300 for unfolding regions of the alpha2 chain of type-I collagen within the context of the microfibril.