ライフサイエンスコーパス: tyrosine phosphorylation

1 tion of p53 transcriptional activity through tyrosine phosphorylation.

2 such as IL-17A and IL-6, and increased STAT3 tyrosine phosphorylation.

3 Shc activation was confirmed by its tyrosine phosphorylation.

4 ed PTPN13, activated c-Abl and triggered tau tyrosine phosphorylation.

5 inase of antiviral pathways, is inhibited by tyrosine phosphorylation.

6 ina, and that it undergoes a light-dependent tyrosine phosphorylation.

7 ocks the capacitation-associated increase in tyrosine phosphorylation.

8 pacitating conditions lead to an increase in tyrosine phosphorylation.

9 A77 1726 inhibited JAK1, JAK2, and STAT3 tyrosine phosphorylation.

10 undergo capacitation-associated increases in tyrosine phosphorylation.

11 HASMC proliferation do not require cortactin tyrosine phosphorylation.

12 ellular bacterial pathogens trigger NMHC-IIA tyrosine phosphorylation.

13 receptor that triggers intracellular protein tyrosine phosphorylation.

14 -mediated Ca(2+) extrusion by promoting PMCA tyrosine phosphorylation.

15 orylation and inhibitory C-terminal sites of tyrosine phosphorylation.

16 hosphorylation of SPL Ser94 without reducing tyrosine phosphorylation.

17 g, and enhances IGF-I receptor-induced IRS-2 tyrosine phosphorylation.

18 nked to high Ser-897 phosphorylation and low tyrosine phosphorylation.

19 nd depleted phosphatases to promote receptor tyrosine phosphorylation.

20 hich are substrates for serine/threonine and tyrosine phosphorylation.

21 munoprecipitate and proNodal increases FGFR3 tyrosine phosphorylation.

22 epair and cell cycle check point proteins by tyrosine phosphorylation.

23 yk2 and Pyk3 undergo increased autocatalytic tyrosine phosphorylation.

24 ting in Src-dependent activation of STAT3 by tyrosine phosphorylation.

25 ibition, suggestive of channel regulation by tyrosine phosphorylation.

26 t VEGF triggered a robust increase in VEGFR2 tyrosine phosphorylation.

27 enuated the integrin alpha5beta1-induced YAP tyrosine phosphorylation.

28 ubunits are post-translationally modified by tyrosine phosphorylation.

29 ation of FAK and decreasing VHR promoted FAK tyrosine phosphorylation.

30 2) phosphatase, which in turn regulates ShcD tyrosine phosphorylation.

31 f CLEC-2 signaling, i.e. the CLEC-2 receptor tyrosine phosphorylation.

32 ugh endocytosis and degradation triggered by tyrosine phosphorylation.

33 Though tyrosine phosphorylation accounts for a minority of tota

34 authors demonstrate iSNAP, a tool to detect tyrosine phosphorylation and activate desired protein en

35 In this work, we show that RIP2 undergoes tyrosine phosphorylation and activation in response to e

36 nalling cascade dynamics associated with Syk tyrosine phosphorylation and activation.

37 yk and Pyk2 stimulation is required for p300 tyrosine phosphorylation and activation.

38 e Src family kinases (SFKs) can promote RIP2 tyrosine phosphorylation and activation.

39 d Cdk2/cyclin A, as well as its responses to tyrosine phosphorylation and altered p21:Cdk2/cyclin A s

40 ed and previously undocumented EGF-dependent tyrosine phosphorylation and binding events, as well as

41 hosphorylation by PKA can coexist with EphA2 tyrosine phosphorylation and block cell retraction induc

42 (B-CLL) cells, resulting in a high level of tyrosine phosphorylation and contributing to their resis

43 osine phosphatases (PTPs) counteract protein tyrosine phosphorylation and cooperate with receptor-tyr

44 on mouse genetic models, we have identified tyrosine phosphorylation and degradation of beta-dystrog

45 Thus, preventing tyrosine phosphorylation and degradation of beta-dystrog

46 ctors activate STAT3 through kinase-mediated tyrosine phosphorylation and dimerization(3,4).

47 the structural basis for activation through tyrosine phosphorylation and dimerization.

48 As and prevented EGFR/CD95 association, CD95 tyrosine phosphorylation and DISC formation.

49 130Cas targeting to FAs is essential for its tyrosine phosphorylation and downstream signaling.

50 hat siRNA knockdown of SOCS1 prolonged IRS-2 tyrosine phosphorylation and enhanced M2 differentiation

51 nvariably been associated with its canonical tyrosine phosphorylation and enhanced transcriptional ac

52 he activated EGFR with CD95, subsequent CD95 tyrosine phosphorylation and formation of the death-indu

53 s1, which was found to be essential for OCT2 tyrosine phosphorylation and function.

54 form of pyruvate kinase M2 (PKM2) undergoes tyrosine phosphorylation and gives rise to the Warburg e

55 dium orthovanadate prior to ethanol restored tyrosine phosphorylation and IL-1beta secretion subseque

56 A prototype that can detect tyrosine phosphorylation and immediately activate auto-i

57 ibitors both prevent parasite-induced band 3 tyrosine phosphorylation and inhibit parasite-promoted m

58 c acid, by stimulating zona occludens (ZO)-2 tyrosine phosphorylation and its dissociation from claud

59 chanistically, LECT2 reduced VEGF receptor 2 tyrosine phosphorylation and its downstream extracellula

60 kin mice with mutations that disrupt nephrin tyrosine phosphorylation and Nck1/2 binding (nephrin(Y3F

61 min), and protracted compared with receptor tyrosine phosphorylation and occurs in multiple cell typ

62 is, revealing key control mechanisms such as tyrosine phosphorylation and phosphoinositide 3-kinase (

63 marked inhibition of insulin-stimulated IRS1 tyrosine phosphorylation and PI3K binding after emetine

64 ockdown of ILK in human LECs triggers VEGFR3 tyrosine phosphorylation and proliferation.

65 ximal IGF-1R signaling events, including IRS tyrosine phosphorylation and recruitment of PI3K, are no

66 Overexpression of ShcA promoted nephrin tyrosine phosphorylation and reduced nephrin signaling a

67 We report here that OSS led to tyrosine phosphorylation and strong, continuous nuclear

68 s unveil the negative regulation of TBK1 via tyrosine phosphorylation and the functional integration

69 Src activation increases kindlin-2 tyrosine phosphorylation and the kindlin-2.Src interacti

70 tes of posttranslational modification (e.g., tyrosine phosphorylation), and participate in nonlinear

71 Osteocyte cell adhesion supports FAK tyrosine phosphorylation, and FFSS triggers FAK dephosph

72 VEGFR2 activation, Src-dependent VE-cadherin tyrosine phosphorylation, and internalization leading to

73 ith interleukin-13 (IL-13) secretion, JAK1/2 tyrosine phosphorylation, and reduced expression of SHP1

74 Thus, GAS is thought to lack tyrosine phosphorylation, and the physiological signific

75 transferase inhibitor, showed an increase in tyrosine phosphorylation, and the sensitivity of the cor

76 Light and tyrosine phosphorylation appear to regulate PKM2 to prov

77 The importance of PI3K activity and tyrosine phosphorylation are two examples of insights co

78 pertoire and supports the concept of protein tyrosine phosphorylation as a key regulatory event in pl

79 Together, our results identify tyrosine phosphorylation as an important regulatory mech

80 of exogenous IGF-1 triggers synergistic IRS1 tyrosine phosphorylation at PI3K-activating residues tha

81 RHBDL4 peptides highlighted the presence of tyrosine phosphorylation at the cytoplasmic RHBDL4 C ter

82 We have shown previously that tyrosine phosphorylation at Tyr-64 and Tyr-155 activates

83 This event led to tyrosine phosphorylation at Tyr627 domain of GAB1 that r

84 es epidermal growth factor-induced cortactin tyrosine phosphorylation both directly and indirectly vi

85 ntagonize the activity of PTKs in regulating tyrosine phosphorylation, but can also play dominant rol

86 has primarily been on serine, threonine and tyrosine phosphorylation, but mounting evidence suggests

87 ing that this pseudophosphatase functions in tyrosine phosphorylation by competing with active phosph

88 ects of SH2 domain overexpression on protein tyrosine phosphorylation by quantitative Western and far

89 troTyr post-translational modification, like tyrosine phosphorylation, can impact calmodulin sensitiv

90 - and spleen tyrosine kinase (Syk)-dependent tyrosine phosphorylation cascade.

91 acterial pathogens often interfere with host tyrosine phosphorylation cascades to control host respon

92 ation of signal pathways mediated by protein tyrosine phosphorylation causes numerous human diseases,

93 reased Ser-897 phosphorylation and decreased tyrosine phosphorylation compared with EphA2 wild type.

94 Tyrosine phosphorylation decreased Ih amplitude at maxim

95 ns can serve as coreceptors for the TCR in a tyrosine phosphorylation dependent manner, and some are

96 signals in a Src family kinase Fyn-mediated tyrosine phosphorylation-dependent manner.

97 hanism by which cells regulate the cortactin tyrosine phosphorylation-dephosphorylation cycle at inva

98 Preventing Canoe tyrosine phosphorylation destabilizes tricellular adhesi

99 f-function and dominant-negative in terms of tyrosine phosphorylation, DNA binding, and transcription

100 further supporting a positive role for Runx1 tyrosine phosphorylation during granulopoiesis, mutation

101 Profiling of nephrin tyrosine phosphorylation dynamics in wild-type mice subj

102 can enhance lanthanide ion luminescence upon tyrosine phosphorylation enable rapid, sensitive screeni

103 een RET/PTC3 and STAT1, followed by a direct tyrosine phosphorylation event, was necessary for STAT1

104 Given the role of tyrosine phosphorylation events in different human infec

105 urface expression, but it is unknown whether tyrosine phosphorylation events of CD2AP are also physio

106 nizes IFN-alpha/beta-induced STAT1 and STAT2 tyrosine phosphorylation, gene expression, and antiviral

107 ion of the balanced modulation of reversible tyrosine phosphorylation has been implicated in the etio

108 Moreover, reduced nephrin tyrosine phosphorylation has been observed in podocytes

109 PKA-independent activation by tyrosine phosphorylation has implications for the mechan

110 ut alternative STAT functions independent of tyrosine phosphorylation have been documented, including

111 yk2(-/-) mice displayed a normal increase in tyrosine phosphorylation, implying that PYK2 is not resp

112 Furthermore, LTB4 decreased insulin receptor tyrosine phosphorylation in hepatocytes, activated the N

113 tyrosine kinase(s) mediating the increase in tyrosine phosphorylation in mouse sperm.

114 Examination of Pyk2 tyrosine phosphorylation in normal polarized cells demon

115 ation of the potential role of extracellular tyrosine phosphorylation in physiological and pathologic

116 ons, balloon injury (BI) induced p115 RhoGEF tyrosine phosphorylation in rat common carotid arteries,

117 proteomic analysis, PAG showed low levels of tyrosine phosphorylation in resting primary mouse CD4(+)

118 define an essential requirement for nephrin tyrosine phosphorylation in stabilizing podocyte morphol

119 We observed an increase in nephrin tyrosine phosphorylation in the presence of Shp2 in cell

120 on of nephrin-CD16 and SHP-1 reduced nephrin tyrosine phosphorylation in transfected human embryonic

121 ersistent and enhanced levels of STAT5BN642H tyrosine phosphorylation in transformed CD8+ T cells led

122 hat IRF4 is activated through c-Src-mediated tyrosine phosphorylation in virus-transformed cells.

123 We observed a marked increase in tyrosine phosphorylation, including the FcRgamma chain a

124 primary mouse CD4(+) T cells; the levels of tyrosine phosphorylation increased and reached a maximum

125 Proteasomal inhibition prolonged IRS-2 tyrosine phosphorylation, increased ubiquitination of IR

126 Pharmacological modulation of tyrosine phosphorylation indicated that, the Src family

127 It blocked STAT1 tyrosine phosphorylation induced either by type I IFN or

128 hosphotyrosines suggested the possibility of tyrosine phosphorylation-induced dimerization, we exclud

129 ivo, and extends the importance of regulated tyrosine phosphorylation into the extracellular environm

130 Tyrosine phosphorylation is a vital mechanism that contr

131 Reversible tyrosine phosphorylation is a widespread post-translatio

132 Nephrin tyrosine phosphorylation is altered in human and experim

133 r time frame and that the MCP-1-induced Pyk2 tyrosine phosphorylation is controlled by the Src family

134 Low-abundance tyrosine phosphorylation is crucial to not only normal b

135 se C-gamma isozymes (PLC-gamma1, -gamma2) by tyrosine phosphorylation is fundamental to the control o

136 Cellular signaling through protein tyrosine phosphorylation is well established in mammalia

137 alyses showed these four proteins had higher tyrosine phosphorylation levels in response to CRP in pl

138 We conclude that tyrosine phosphorylation might be a mechanism involved i

139 talytic domain, cytochrome c oxidase and its tyrosine phosphorylation, mitofusins and PGC-1alpha.

140 face receptors containing ITAM, ITIM or ITSM tyrosine phosphorylation motifs to the promiscuous cell-

141 rotein tyrosine kinases in orchestrating the tyrosine phosphorylation networks and in target-based dr

142 ificity of these inhibitors for FGF2 because tyrosine phosphorylation of a different substrate of Tec

143 production, calcium (Ca(2+)) responses, and tyrosine phosphorylation of a number of proteins.

144 the regulatory subunit of the PI3K, through tyrosine phosphorylation of adapter protein insulin rece

145 TCRs modulated alpha7 currents via tyrosine phosphorylation of alpha7 nicotinic receptors (

146 C-2 receptors are known to activate Syk upon tyrosine phosphorylation of an immune tyrosine activatio

147 se of loss of Janus kinase 3 (JAK3)-mediated tyrosine phosphorylation of BCRP.

148 Moreover, EGFR/Src-signaling triggers the tyrosine phosphorylation of beta4 integrin, which, in tu

149 ding partner Shc1 is dependent on Syk, as is tyrosine phosphorylation of both partners.

150 Blocking the tyrosine phosphorylation of C-Raf with Src family inhibi

151 f CitK that are phosphorylated and show that tyrosine phosphorylation of CitK impairs cytokinesis.

152 Together, these findings demonstrate that tyrosine phosphorylation of cortactin at Y446 residue is

153 ins two intracellular tyrosine residues, and tyrosine phosphorylation of Cx32 has been detected after

154 epithelial cell-cell junctions and promotes tyrosine phosphorylation of E-cadherin, beta-catenin, an

155 endothelial function, mediated by increased tyrosine phosphorylation of eNOS and excess Nox2-derived

156 s an increase in SFK activity and downstream tyrosine phosphorylation of enzymes, adaptors, and cytos

157 of modulating animal behavior, extracellular tyrosine phosphorylation of EphBs may represent a previo

158 Although tyrosine phosphorylation of extracellular proteins has b

159 Over-expression of VHR decreased tyrosine phosphorylation of FAK and decreasing VHR promo

160 t (i) the interaction of FGF2 with Tec, (ii) tyrosine phosphorylation of FGF2 mediated by Tec in vitr

161 nner leaflet along with Tec kinase-dependent tyrosine phosphorylation of FGF2, (ii) PI(4,5)P2-depende

162 timulates membrane pore formation based upon tyrosine phosphorylation of FGF2.

163 process is regulated by Tec kinase-mediated tyrosine phosphorylation of FGF2.

164 shown that non-receptor tyrosine kinases and tyrosine phosphorylation of focal adhesion proteins such

165 Complete maturation of ULBP2 required tyrosine phosphorylation of HSP60 which was mediated by

166 resistance and decreased insulin-stimulated tyrosine phosphorylation of insulin receptor beta (IRbet

167 lief of IRS1 inhibition and IGF-1R-dependent tyrosine phosphorylation of IRS1.

168 IGF-1 receptor (IGF-1R) but fails to promote tyrosine phosphorylation of IRS1.

169 Engagement of CD28 leads to tyrosine phosphorylation of its cytoplasmic region and r

170 sed the level of IL-2R subunits and promoted tyrosine phosphorylation of Jak3 and STAT5.

171 findings support a novel mechanism by which tyrosine phosphorylation of JAM-A Y280 regulates epithel

172 Tyrosine phosphorylation of Lyn and Syk was altered in P

173 Tyrosine phosphorylation of membrane receptors and scaff

174 nhibition, and this was coupled to increased tyrosine phosphorylation of MET and RON.

175 s was accompanied by increases in serine and tyrosine phosphorylation of mGluR5, which can decrease m

176 mechanism revealed that FAK regulates YAP by tyrosine phosphorylation of MOB1, inhibiting core Hippo

177 TNF induces tyrosine phosphorylation of Mule, which subsequently dis

178 rtex (DLPFC), we found striking decreases in tyrosine phosphorylation of N-methyl-D aspartate (NMDA)

179 echanism of NLRP3 inflammasome regulation by tyrosine phosphorylation of NLRP3 at Tyr861.

180 diated activation of TrkB- and TrkB-mediated tyrosine phosphorylation of NMDA receptors.

181 that, among the RhoGEFs tested, MCP1 induced tyrosine phosphorylation of p115 RhoGEF but not of PDZ R

182 mportantly, imatinib and nilotinib increased tyrosine phosphorylation of p130Cas, FAK, PXN and radial

183 elated drug, nilotinib, strikingly increases tyrosine phosphorylation of p130Cas, focal adhesion kina

184 e other hand, we observe no reduction in the tyrosine phosphorylation of parkin and the parkin substr

185 ifically, in the present study, we show that tyrosine phosphorylation of PKD2 at residue Y87 defines

186 1) kinase by enhancing c-Src kinase-mediated tyrosine phosphorylation of Plk1.

187 f Ca(2+) efflux is reversed by E2-stimulated tyrosine phosphorylation of PMCA.

188 ed at the trailing edge, suggesting that the tyrosine phosphorylation of Pyk2 is spatially regulated

189 ing pathway by which Agrin-LRP4-MuSK induces tyrosine phosphorylation of Rapsn, which is required for

190 Tyrosine phosphorylation of slit diaphragm molecules can

191 Unexpectedly, and differently from VAV1, tyrosine phosphorylation of SOS1, ARHGEF1, and DOCK2 is

192 ls with Gal3 knockdown exhibited upregulated tyrosine phosphorylation of spleen tyrosine kinase and s

193 y cells and the effect of FK228 treatment on tyrosine phosphorylation of STAT3 (pYSTAT3) and RAD23B e

194 reatment with interleukin-6 (IL-6) increased tyrosine phosphorylation of STAT3 and evoked a parallel

195 JAK2 inhibition led to significantly reduced tyrosine phosphorylation of STAT3 and markedly reduced c

196 Erasin inhibits tyrosine phosphorylation of STAT3 with selectivity over

197 IL-2-induced tyrosine phosphorylation of STAT5 (pSTAT5) was proportio

198 nd time-dependent manner that coincides with tyrosine phosphorylation of STAT5.

199 onsistent with this, thrombin did not induce tyrosine phosphorylation of Syk and the FcRgamma chain i

200 controls early TCR signaling events, such as tyrosine phosphorylation of TCRzeta, ZAP70, and LAT and

201 d barrier function and excessive Src-related tyrosine phosphorylation of the adherens junction protei

202 Tyrosine phosphorylation of the beta chain has been stud

203 domain residue Tyr(243) Unlike for Cx43, the tyrosine phosphorylation of the Cx32CT increased gap jun

204 broblasts, through a mechanism that involves tyrosine phosphorylation of the epidermal growth factor

205 In exploring the mechanism whereby tyrosine phosphorylation of the erythrocyte anion transp

206 criptional elongation based on CK2-dependent tyrosine phosphorylation of the globular domain of H2A.

207 diminished autocrine Igf2 production; basal tyrosine phosphorylation of the insulin and IGF1 recepto

208 4-induced M2 gene expression correlated with tyrosine phosphorylation of the insulin receptor substra

209 Evidence indicates that tyrosine phosphorylation of the intracellular tail of ne

210 38alpha MAPK, which also blocked KOR-induced tyrosine phosphorylation of the inwardly rectifying pota

211 a subset of BCR signaling events, including tyrosine phosphorylation of the kinase SYK, the calcium

212 Elevated tyrosine phosphorylation of the latent transcription fac

213 GPR30 further inhibits PMCA activity through tyrosine phosphorylation of the pump.

214 nds to the insulin receptor (IR) and induces tyrosine phosphorylation of the receptor and insulin rec

215 and Cbl-b led to an increased ligand-induced tyrosine phosphorylation of the receptor.

216 Here, we show that tyrosine phosphorylation of the T cell adapter protein L

217 We have previously established that tyrosine phosphorylation of the transmembrane protein ne

218 ransfected into Jurkat cells showed that the tyrosine phosphorylation of the type II was the same as

219 rated that PTP1B was a negative regulator of tyrosine phosphorylation of the tyrosine kinase TRKB, th

220 We found that ERBB4 stimulates tyrosine phosphorylation of the VAV3 activation domain,

221 Importantly, chemokine-induced tyrosine phosphorylation of these GEFs is fully mediated

222 Inhibition of PTP1B led to increased tyrosine phosphorylation of TRKB in the brain, which wou

223 ownstream of PDGFRs to enhance PDGF-mediated tyrosine phosphorylation of various signaling intermedia

224 Src tyrosine kinase activity and tyrosine phosphorylation of VE-cadherin were increased i

225 Src activity and tyrosine phosphorylation of VE-cadherin were increased i

226 t affect the ability of leukocytes to induce tyrosine phosphorylation of VE-cadherin.

227 terestingly, while ANGPTL4 modestly enhanced tyrosine phosphorylation of VEGF receptor 2, promotion o

228 We show that tyrosine phosphorylation of VEGFR2 is significantly elev

229 We demonstrate that tyrosine phosphorylation of WASP in response to stimulat

230 ing ITCH-WBP2 interactions via EGFR-mediated tyrosine phosphorylation of WBP2 and TAZ/YAP competitive

231 pid rafts, followed by abrogation of protein tyrosine phosphorylation of ZAP70, phospholipase C-gamma

232 ich links the opposing effects of serine and tyrosine phosphorylations of IRS1 and can modulate insul

233 ition occurs isothermally and is governed by tyrosine phosphorylation on LAT.

234 t on the effect of this EGFR-dependent GSTP1 tyrosine phosphorylation on the interaction of GSTP1 wit

235 ever, a full understanding of the effects of tyrosine phosphorylation on the ligand interactions and

236 o significant differences were evident in IR tyrosine phosphorylation or the downstream elements, AKT

237 In addition, MCP1-induced cortactin tyrosine phosphorylation, p21Cip1 degradation and HASMC

238 inhibitors attenuated MCP1-induced cortactin tyrosine phosphorylation, p21Cip1 degradation and HASMC

239 significant, dose-dependent increase in EGFR tyrosine phosphorylation, particularly of sites correspo

240 Consistent with reduced WASP tyrosine phosphorylation, phagocytosis, chemotaxis, and

241 Tyrosine phosphorylation plays an important role in many

242 of keratin primary amino acid sequences, and tyrosine phosphorylation predictions, extracted from pub

243 ons, our data support a model by which Nlgn1 tyrosine phosphorylation promotes the assembly of an exc

244 CatSper1 processing correlates with protein tyrosine phosphorylation (pY) development in sperm cells

245 In vitro hnRNPA2 tyrosine phosphorylation reduces hnRNPA2 phase separatio

246 own Syndrome-related kinase dual-specificity tyrosine phosphorylation-regulate kinase 1a (Dyrk1a) and

247 armacological inhibitors of dual-specificity tyrosine phosphorylation regulated kinases and cdc-like

248 ning region annotated to the calcium-binding tyrosine phosphorylation-regulated gene (CABYR).

249 selective inhibitor of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) and cel

250 rough interactions with the dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A).

251 inase, a fly homolog of the dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A); h

252 on of the regulatory kinase dual-specificity tyrosine phosphorylation-regulated kinase 1A was shown t

253 The dual-specificity tyrosine phosphorylation-regulated kinase DYRK1A is a se

254 d negative signals from the dual-specificity tyrosine phosphorylation-regulated kinase family kinase

255 ver this included Cabyr, the calcium-binding tyrosine phosphorylation-regulated protein encoded trans

256 tified a novel role for the dual specificity tyrosine-phosphorylation-regulated kinase DYRK1A in regu

257 Activation of dual-specificity tyrosine-phosphorylation-regulated kinases 1A and 1B (DY

258 e found that VEGF-A stimulation can induce a tyrosine phosphorylation response in CD2AP in podocytes,

259 ivo growing human brain tumors, we show that tyrosine phosphorylation shifts the GSTP1 dimer-monomer

260 Here, we identified a single cortactin tyrosine phosphorylation site (Y499) to be important for

261 In conclusion, we have characterized a tyrosine phosphorylation site in Aplysia cortactin that

262 In contrast, only one E2 tyrosine phosphorylation site in BPV-1 (tyrosine 102) an

263 Antibodies against a tyrosine phosphorylation site in the intracellular juxta

264 Our data also show that multiple tyrosine phosphorylation sites of CDCP1 are important fo

265 o-localized with antibodies directed against tyrosine phosphorylation sites within the receptor kinas

266 horylation sites including 366 low-abundance tyrosine phosphorylation sites, with high reproducibilit

267 horylation of the receptor at all five major tyrosine phosphorylation sites.

268 fic ARIH2 transcription was regulated by the tyrosine phosphorylation states of HoxA9 and HoxA10.

269 By quantitatively assessing the tyrosine phosphorylation status of activated kinases in

270 lecular level, DUSP3 deficiency impaired Syk tyrosine phosphorylation, subsequently reducing phosphor

271 Cortactin is a Src tyrosine phosphorylation substrate that regulates multip

272 ime-dependent and spatially specific protein tyrosine phosphorylation successfully migrate.

273 cts in HEK 293T cells and observed increased tyrosine phosphorylation, suggesting increased ABL1 kina

274 modifications such as lysine acetylation and tyrosine phosphorylation, suggesting metabolic and signa

275 d STAT proteins, classically associated with tyrosine phosphorylation, support tumor development as t

276 s in greater PTPRK expression and lower EGFR tyrosine phosphorylation than either ligand alone.

277 ma membrane without blocking the increase in tyrosine phosphorylation that accompanies capacitation.

278 moting the subsequent stimulation of protein tyrosine phosphorylation that associates with fertilizin

279 es the activity of androgen receptor (AR) by tyrosine phosphorylation to fuel the growth of hormone-r

280 3A (JHDM2a) complex, which modifies KDM3A by tyrosine phosphorylation to regulate the transcriptional

281 fficking of VEGFR2, and site-specific VEGFR2 tyrosine phosphorylation to study differences in induced

282 Insulin-stimulated Irs1 tyrosine phosphorylation (Tyr(P)(Irs1)) was enhanced by

283 we describe an inverse relationship between tyrosine phosphorylation (Tyr(P)) and serine phosphoryla

284 pre-diabetic or diabetic showed reduced IRS2 tyrosine phosphorylation upon insulin stimulation, indic

285 searched for novel host proteins undergoing tyrosine phosphorylation upon L. monocytogenes infection

286 tion of FcepsilonRII activated intracellular tyrosine phosphorylation via Syk in B cells but not in m

287 Imatinib and nilotinib-induced tyrosine phosphorylation was dependent on expression of

288 The pattern of tyrosine phosphorylation was similar to that induced by

289 and SYK-dependent counterregulation of MyD88 tyrosine phosphorylation, we have demonstrated that the

290 Differences in tyrosine phosphorylation were associated with difference

291 ion factors, 32 new targets of EPO-modulated tyrosine phosphorylation were defined.

292 thanol treatment markedly decreased cellular tyrosine phosphorylation, whereas administration of the

293 ignaling activates binding sites, such as by tyrosine phosphorylation, which enables protein recruitm

294 Deletion of IP6K1 abolishes alpha-actinin tyrosine phosphorylation, which is known to be regulated

295 EGF leads to a striking increase in EGFRvIII tyrosine phosphorylation while silencing HB-EGF attenuat

296 By mimicking RAD51 tyrosine phosphorylation with a nonnatural amino acid, p

297 ates cell adhesion and migration by bridging tyrosine phosphorylation with cytoskeletal remodeling, t

298 in the TKI-resistant mutants suppresses EGFR tyrosine phosphorylation, with the most significant effe

299 tyrosine-binding competent SH2 domain and on tyrosine phosphorylation within NS5A.

300 Second, we found conservation of tyrosine phosphorylation within the RNP1 and RNP2 consen