ライフサイエンスコーパス: unable

1 ses, yet conventional imaging modalities are unable to access intricate biomolecular information with

2 Cas proteins and restriction enzymes are unable to access the phage DNA throughout the infection,

3 tudied, yet sediment transport models remain unable to account for the rapid transport of sediment re

4 Classical capture models are unable to account for this pronounced inverse kinetic is

5 r of compounds observed in our study, we are unable to account for ~20% of the carbon flow.

6 t least in part, the result of females being unable to accumulate the energy reserves necessary to ma

7 ions between adsorbed species and, thus, are unable to accurately describe the formation of adsorbed

8 Therefore, we were unable to accurately estimate the timing of each invasio

9 normalized by sequencing depth and therefore unable to accurately measure global changes in chromatin

10 ration is suppressed in WAS patient MDMs and unable to achieve normal maximal activity when stressed,

11 us, the applied taVNS device or protocol was unable to achieve significant effects on autonomic inner

12 raditional analytical techniques have proven unable to achieve this goal.

13 An NF2 mutant deficient in lipid binding is unable to activate the Hippo pathway in response to osmo

14 Suppressor analysis reveals that cells unable to activate this sigma(I) stress response acquire

15 When compared to existing methods - unable to address all these important tasks using a sing

16 SIVcpz Nef is, however, unable to antagonize human BST-2, and Vpu was consequent

17 ver, current genome-wide methods are largely unable to assay essential genes which are not amenable t

18 One bent aldehyde stands out as unable to assemble into high-symmetry cages-and the same

19 (18%) were also common but were often rated 'unable to assess' (32%, 43%, and 44% of assessments, res

20 nts of attention decreased the frequency of 'unable to assess' ratings to 11%.

21 the highest prevalence and were never rated "unable to assess," while inattention (36%), disorientati

22 d sequences in metagenomic data sets, we are unable to assign a function to 50-90% of genes, or more.

23 energy consumption, and explain why MCDI is unable to attain the performance of ED, even with ideal

24 revention (BEEP) study who were unwilling or unable to attend OFC was developed.

25 these promoters gain DNA methylation and are unable to be activated upon differentiation.

26 r targets had sensitivities of >=75% or were unable to be calculated due to low prevalence in the stu

27 entilation for greater than 2 weeks who were unable to be extubated and determined to have reasonable

28 urprisingly, we observed that vDeltaUL47 was unable to be horizontally transmitted to naive chickens,

29 linical isolates, both animal and human, are unable to be isolated and characterized, limiting our un

30 (KI) (/KI) mice that express a mutant MHC II unable to be ubiquitinated or mice that lack membrane-as

31 The swapped form of Nck-SH3.1 is unable to bind CD3e, possibly representing an inactive f

32 nstitution of RCC cells with a PRDM16 mutant unable to bind CtBPs nullifies PRDM16's effects on both

33 in particular since all D/N Vif mutants were unable to bind Cul5 and some mutants additionally failed

34 rast, isolated FANCD2 is a homodimer that is unable to bind DNA, suggestive of an autoinhibitory mech

35 exclusively localized in the cytosol and is unable to bind DNA.

36 BPV-1 Y102E was unable to bind E1 and did not replicate in a transient i

37 A UgpB mutant unable to bind G3P is constitutively active as a chapero

38 ently, an HO2 catalytic site variant that is unable to bind heme exhibits a constant low protein leve

39 ere distinct and that an FMRP mutant that is unable to bind ribosomes still promoted localization of

40 es a TB19/TB38 biparatopic antibody would be unable to bind the CD73 dimer in a bivalent manner, impl

41 ohexamer into two heterotetramers, which are unable to bind the promoter DNA optimally due to steric

42 Nedd8 conjugated VHL is unable to bind to p53 thereby preventing the induction o

43 n by using knock-in of a mutant p27 that was unable to bind to Skp2.

44 vity of high-risk HPV E7 used variants of E7 unable to bind to UBR4.

45 wastewater sensing, MESe technology has been unable to bridge the gap between the laboratory and real

46 Consequently, single-scale models are unable to capture the critical cross-scale interactions

47 g models can be difficult to tune and may be unable to capture the dynamics of non-extracellular prot

48 LmCen(-/-) is safe since it is unable to cause disease in immunocompromised mice, induc

49 A, as both hla and hla DeltafakA mutants are unable to cause necrosis of the skin.

50 HS069Deltacap was unable to cause signs of systemic disease during a pig c

51 ic interactions, which single-color tsMSQ is unable to characterize.

52 roduced in vivo, the bacteriophage switch is unable to choose the lytic life cycle showing that the C

53 racts with Cas9, and Cas9-Acr complexes were unable to cleave DNA.

54 05A rendered Escherichia coli-expressed Lpro unable to cleave the synthetic substrate pro-ISG15 while

55 ay a key role in priming Tfh responses, were unable to cluster to the interfollicular regions of the

56 r and extrahepatic tissues in obese-NAFLD is unable to compensate for the increase in insulin resista

57 abeta T, and CD4(+) alphabeta T(H)1(*) cells unable to compensate for this deficit.

58 educed stability and missence mutations were unable to complement TMTC3 rescue of gastrulation in Xen

59 Patients unable to complete (223)Ra treatment because of progress

60 ation at 59.0% (95% CI, 51.6-65.9) and being unable to complete normal activities for 3 or more days

61 d at different cell cycle stages and so were unable to complete the cell cycle, thus defining genes n

62 upture of the same Achilles tendon, or being unable to complete the questionnaires.

63 e also observe that elongating ribosomes are unable to complete translation because they are blocked

64 publications or journals published in - were unable to completely differentiate applicants with and w

65 , but current models of helping behavior are unable to completely parse apart whether the reported be

66 not review grey literature and that we were unable to conduct moderation analyses for several prespe

67 , or (c) 3 or more consecutive days of being unable to conduct usual activity--yielded a sensitivity

68 We were unable to confirm a benefit of hydroxychloroquine or chl

69 However, we were unable to confirm that 3-MPA inhibited PEPCK-M enzyme ac

70 This is often imprecise and unable to consider individual patient characteristics.

71 Previous studies have been unable to constrain the location between possibilities r

72 ing vaginal microbiotas, mutant F. nucleatum unable to consume sialic acids was impaired in vaginal c

73 Despite extensive efforts, the journal was unable to contact Dr.

74 pression in Foxp3(+) T(reg) cells, which are unable to control colitis in a cell-transfer model of th

75 s activated in an uncontrolled manner and is unable to control infection in a timely fashion.

76 estrain bacteria growth, some granulomas are unable to control Mtb growth, leading to bacteria and in

77 tality in immune-deficient patients, who are unable to control viral dissemination.

78 hanged to the ones present in CsGA1ox/ds was unable to convert GA(9) to GA(4), highlighting the impor

79 RIPK1-deficient cells are unable to cope with energetic stress and are vulnerable

80 conjugated to biotinylated saporin, a toxin unable to cross cell membranes.

81 able to cleave galactosylsphingosine, and is unable to cross-correct.

82 r two FLT3 inhibitors, these modalities were unable to cure AML or significantly extend the lives of

83 regimens suppress HIV-1 replication but are unable to cure infection.

84 e sprayed with Fe in their leaves, they were unable to deactivate root Fe uptake.

85 by aeration was the least effective method, unable to decrease As to below 10 mug/L, which was attri

86 abuse in different male populations but were unable to define a mechanism.

87 ts observational nature, meaning that we are unable to definitively determine causality.

88 ies of solid tumors treated with ICB, we are unable to demonstrate favorable response to ICB in patie

89 in the underweight subgroups, this study was unable to demonstrate that nutritional status modified t

90 Moreover, this antibody was unable to detect activated Rac1 in membrane ruffles indu

91 Surprisingly, we were unable to detect any specific change in the expression o

92 er was low (42.8%) because the technique was unable to detect capsular or vascular invasion, although

93 d to use sulfate for respiration but we were unable to detect DSR in these isolates.

94 whereas the commercial ELISA kit was instead unable to detect egg white in the same samples.

95 n transmission if blood screening assays are unable to detect HIV in donations from infected donors.

96 Moreover, in one elite controller, we were unable to detect intact proviral sequences despite analy

97 en requires labor-intensive surveys that are unable to detect rapid or unanticipated environmental ch

98 ative to the spiked control brains), we were unable to detect the other individual ABX in brain homog

99 treatment intent (curative, noncurative, or unable to determine) or as different systemic or local t

100 By contrast, scientists have been unable to develop a physical measure linked to perceived

101 enhanced in irradiated ASMKO mice, which are unable to develop intestinal failure injury.

102 hese syn-BNP antibiotics, but they were also unable to develop resistance to these antibiotics in lab

103 In the absence of FAO, the progenitors are unable to differentiate and exhibit altered histone acet

104 e accumulation of clonal myeloid blast cells unable to differentiate into mature leukocytes.

105 Memory T cells are unable to differentiate into the Th2 phenotype, and acqu

106 However, these studies were unable to differentiate the state of infection, i.e., ac

107 lin-like growth factor-binding protein 7 was unable to differentiate transient from persistent acute

108 to each of these areas: (i) metabolomics is unable to differentiate whether a mutation has resulted

109 al and technical limitations, they have been unable to directly test the stress-reactivity hypothesis

110 imaging studies in humans have thus far been unable to discern between these two models, though this

111 iminants used for species identification are unable to discern hybrids, so molecular methods are requ

112 3500 Pa, whereas the standard DI output was unable to distinguish between these two groups of cells.

113 ion of this correlation renders the ribosome unable to distinguish correct from incorrect tRNAs.

114 asure the total concentration of ALP but are unable to distinguish enzyme isotypes.

115 orithms or systems, which existing tools are unable to do.

116 on and reduction, respectively, and are thus unable to drive photoelectrochemical (PEC) water splitti

117 uffer from high false-positive rates and are unable to effectively differentiate direct miRNA targets

118 y where creeks exhibit morphologies that are unable to efficiently drain adjacent marsh platforms.

119 demonstrated that cross-presenting pDCs were unable to efficiently prime CD8 T cells by themselves, b

120 Native luciferases were unable to efficiently process the analog, but a compleme

121 Thus, CD4-MBL CAR-T cells are unable to eliminate the FDC-associated HIV reservoir, an

122 As these defective proviruses are unable to encode intact and replication-competent viruse

123 In lgo-2 mutant plants where cells are unable to endoreplicate fully, cotyledon organ size is a

124 G-containing ICs with an Fc engineered to be unable to engage FcRn did not.

125 njection, but many ophthalmic treatments are unable to enter the eye or reach the posterior segment a

126 have effector function, the immune system is unable to eradicate the malignant clone.

127 While individuals seem to be unable to escape the fitness effects of their morphology

128 se previous studies, being correlative, were unable to establish any functional role for the false mo

129 d using traditional group-level analyses was unable to estimate either baseline memory performance or

130 are not reliable, and the clinician is often unable to evaluate if the lesion is progressing or has r

131 dence of large reductions in SFA, but we are unable to exclude more modest benefits.

132 Both KHAP1 and KHAP2 null mutants are unable to execute cytokinesis but are able to traffic GT

133 n enhanced recovery option for those who are unable to exercise after injury ABSTRACT: Chronic pain a

134 ins unknown and may benefit patients who are unable to exercise as a result of immobilization.

135 totagmin VII, respectively, invadopodia were unable to expand and elongate.

136 set-ups, I argue that these differences are unable to explain the lack of replication in Markel, 202

137 cles and collectors, and the DLVO theory was unable to explain the observed particle attachment.

138 t models to describe adhesive properties are unable to explain these experimental observations, inste

139 al that unlike FFA4-S, the longer isoform is unable to facilitate phosphorylation of ERK1/2 in cells

140 We were also unable to find a difference in 24-hour culture positivit

141 To date, we are unable to find critical care specific literature on the

142 -inactivated VLs had tortuous paths and were unable to find their nest, whereas ants from the untreat

143 Cyanobacteria unable to fix atmospheric nitrogen have evolved sophisti

144 les infected with a B. japonicum nifH mutant unable to fix nitrogen, nodules doubly infected by both

145 data suggest OHCs are low-pass filtered and unable to follow high-frequency signals.

146 the large subunit in a non-functional state unable to form a cleavage-competent effector complex.

147 patterned clump of spherical cells that were unable to form gametophores, demonstrating that ROP is e

148 ors are obligate dimers, and because ATF4 is unable to form highly-stable homodimers, we hypothesized

149 Mutants are unable to form occlusive venous and arterial thrombi in

150 eered cells accumulate aberrant 50S subunits unable to form stable 70S ribosomes.

151 ed peptides and chimeric constructs that are unable to form the interclass 5-HT(2A)R-mGluR2 complex,

152 In addition, in mice unable to form the membrane attack complex, the tumor pr

153 We developed a Brpt5.5 mutant that was unable to form the tetramer and was concordantly incapab

154 duced growth and invasion in vitro, and were unable to form xenografted tumors.

155 ession following cisplatin treatment, RPA is unable to fully protect ssDNA created by cisplatin adduc

156 to the oolemma, TMEM95-deficient sperm were unable to fuse with the egg membrane or penetrate into t

157 Unable to generate new enzyme paradigms and metabolic ne

158 at induces OPA1 cleavage, we show that cells unable to generate S-OPA1 are more sensitive to this str

159 ignature marked by Sca1, but upon injury are unable to generate Sca-1(+)/Clu(+) revSCs and could not

160 to attend clinic (bedridden), psychotic, or unable to give informed assent or consent.

161 09 homologue in Mycobacterium bovis BCG, was unable to grow following the conditional depletion of BC

162 utant was more susceptible to vancomycin and unable to grow on MacConkey plates, indicating an altera

163 Simulated trees were unable to grow roots rapidly enough to mediate the hydra

164 ed to the mitochondria or cytosol were still unable to grow tumours.

165 s who (1) first presented with GMG, (2) were unable to identify the time of onset of OMG or GMG, (3)

166 assessment by conventional imaging is often unable to identify which patients will achieve durable c

167 If countries are even unable to implement their current NDCs, the whole world

168 e3 in SCNT-derived blastocysts, but this was unable to improve their preimplantation development.

169 GSK3beta implies that phosphorylated AKT was unable to inactivate GSK3beta.

170 which no longer interacted with TRIM21, was unable to increase Nrf2-mediated transcriptional activat

171 ant infection in the genital tract alone was unable to induce any significant hydrosalpinx.

172 found that these pairs of single stimuli are unable to induce any synaptic modification in 1.3 and 1.

173 ilar to activated AKT in LAD cells, although unable to induce epithelial-mesenchymal transition (EMT)

174 Interestingly, it was unable to induce excystation and increased trophozoite s

175 calreticulin, HSP70, and HMGB1); however, is unable to induce ICD.

176 esent so-called "fake antigens," as they are unable to induce immunity, but may react with and cross-

177 ed with TvWT or T. virens Deltasm1, a mutant unable to induce ISR.

178 e WT CLASP2, the CLASP2 C-terminal mutant is unable to induce MT stabilization or promote early HIV-1

179 esize inositol pyrophosphates (PP-InsPs) are unable to induce the ESR.

180 es not promote high-affinity DNA binding, is unable to induce the same allosteric response as nickel.

181 iate the infection of human gut cells but is unable to infect human lung cells.

182 -type (WT) LIN28B or a LIN28B mutant that is unable to inhibit let-7 processing increases the penetra

183 oxic doses, atorvastatin and mevastatin were unable to inhibit Mtb growth in THP-1 cells.

184 g by penicillin-binding protein 2 (PBP2) are unable to initiate polarized division, while cells treat

185 ikely (>90% probability) that mangroves were unable to initiate sustained accretion when RSLR rates e

186 infection clearance, but only if the drug is unable to interfere with infection of the first cells.

187 during maturation and are immotile and thus unable to invade new host cells.

188 Because in vivo experimental methods are unable to isolate or control individual factors of the T

189 to visualize such interactions, they remain unable to label mitochondria and lysosomes simultaneousl

190 with IE were significantly more likely to be unable to learn the spatial discrimination task (p = 0.0

191 However, these indirect methods are unable to link networks to the hardwiring that underlies

192 t parasites lacking the esophageal gland are unable to lyse ingested immune cells within the esophagu

193 dria with disrupted inner membranes that are unable to maintain a proton gradient, while expelling th

194 ods, the observed dynamics for all taxa were unable to maintain current community composition, highli

195 th transfection and infection conditions was unable to maintain high episome copy numbers in epitheli

196 CD5 was conditionally ablated, T cells were unable to maintain higher expression of the cytoplasmic

197 in normal health, and individuals lacking or unable to make antibodies are at risk.

198 Important limitations include being unable to measure children's underlying health status an

199 phocytes are completely pilot-less: they are unable to migrate toward chemokines despite their normal

200 One limitation to note is that we were unable to model for changes in multimorbidity during our

201 r COVID-19 based on symptoms but awaiting or unable to obtain testing.

202 Despite this, a Synechococcus strain was unable to outcompete a Prochlorococcus strain in co-cult

203 raction with CH(3)CH(2)Cl and is, therefore, unable to overcome the characteristic distortivity of th

204 energetic cost that animals are unwilling or unable to pay under some conditions.

205 Many antibiotics are either unable to penetrate the outer-membrane or are excluded b

206 antibodies, are structurally complex and are unable to penetrate the skin barrier.

207 e infections, many clinical laboratories are unable to perform susceptibility testing due to the lack

208 The converted m/m males are flightless, unable to perform the nuptial flight required for mating

209 quivalently to 3D4/31 cells; however, it was unable to persistently colonize the nasal cavity of inoc

210 nts, each with lactose from HepII but fixed (unable to phase-vary) LOS HepI glycans extended beyond t

211 - iPSCs lacked IL-10RB mRNA expression, were unable to phosphorylate STAT3, and failed to reduce LPS

212 Finally, we show that MSL10 is unable to potentiate cell swelling-induced death when ph

213 e official forecast and computer models were unable to predict rapid intensification of these storms.

214 Additionally, they are unable to predict whether the drug-induced gene expressi

215 In C57BL/6 mice, which are unable to present the immunodominant epitope, CSP-based

216 and folding of DYRK1, resulting in a kinase unable to preserve VHL function and lacking glioma suppr

217 pproval to treat multiple sclerosis (MS) are unable to prevent inflammatory tissue damage in the cent

218 s subpopulation, memory B-cell depletion was unable to prevent relapse, which was probably caused by

219 erestingly, isolated DCs alone, however, are unable to produce CCL22, but instead require T cell help

220 ns, but that global inhibitory networks were unable to produce input-output transformations that matc

221 a symbiologicarpus, P. luteoviolacea mutants unable to produce MACs are capable of stimulating metamo

222 nded GPA33(high) Treg cells are suppressive, unable to produce proinflammatory cytokines, and exhibit

223 Strains unable to produce surfactin exhibited an ~50-fold reduct

224 electric figure-of-merit materials have been unable to produce the voltage and power levels required

225 re teratospermia and Adad2 mutant germ cells unable to progress beyond round spermatid.

226 While many response biomarkers will be unable to progress from their status as markers of biolo

227 acrophages or skin fibroblasts in vitro were unable to proliferate, and overexpression of Mfrn1-GFP o

228 dered to be terminally differentiated cells, unable to proliferate.

229 variant that disrupts binding to USP-46 was unable to promote USP-46 abundance in vivo Finally, siRN

230 the inner core lipopolysaccharide (LPS) were unable to propagate phage LL5, as were mutants deficient

231 ised during plating, making it intrinsically unable to protect Li.

232 However, these studies are unable to prove biologic plausibility and causality as r

233 cies or local communities and have thus been unable to provide a general evaluation of the overall fr

234 s N(2) O was suppressed in solvents that are unable to provide hydrogen bonding to the second-sphere

235 fy the time of onset of OMG or GMG, (3) were unable to provide information about previous treatments

236 , even the most sophisticated approaches are unable to provide meaningful answers when the user lacks

237 They are unable to provide the high demand of multiplexing, high-

238 he advantage of large-sample sizes, they are unable to quantify the cellular basis of structural or f

239 ely, traditional HSI analysis methods remain unable to rapidly process the volume of hyperspectral da

240 a membrane-impermeable CA inhibitor that is unable to reach the brain tissue, had no effect.

241 dered phase which is kinetically metastable, unable to reach, spontaneously, the ferroelectric (FE) g

242 ecognize presumptive immunity in individuals unable to receive live, attenuated vaccines may have emp

243 dge, other indexing methods have so far been unable to record abundances efficiently across large dat

244 ll lines; however, sensitive cell lines were unable to recover and replicate DNA even when the inhibi

245 ivo We were able to recover S411A Kunjin but unable to recover T407A Kunjin.

246 In turn, these models may be unable to reliably detect biological effects.

247 However, current bioprinters are unable to reliably print the fundamental unit of all liv

248 nder extreme conditions, SARS-CoV-2 virus is unable to replicate in these mosquitoes and therefore ca

249 tion of PPE51 rendered M. tuberculosis cells unable to replicate on propionamide, glucose, or glycero

250 Therefore, we were unable to replicate the "qM" component and its correspon

251 ological states in other individuals but are unable to represent others' beliefs.

252 al arginine rendered both HPV16 and HPV18 E7 unable to repress differentiation-related gene expressio

253 Despite extensive efforts, we were unable to reproduce the finding that glutamate, AP5, and

254 Recent studies have been unable to reproduce the original experiments in the beta

255 bly-deficient variants of these proteins are unable to rescue microcompartment formation, highlightin

256 This mutant was unable to rescue the DeltaponB-ponA (ts) strain, which l

257 nate (i.e., the glycosidic torsion angle) is unable to resolve the intermediates.

258 Thus, oocytes are unable to respond immediately to DNA damage, but instead

259 pate that such VSDs become dysfunctional and unable to respond to changes in transmembrane voltage, w

260 simultaneous deletion of Msi1 and Msi2 were unable to respond to light and displayed severely disrup

261 ns altered for phosphotransfer activity were unable to restore atxA transcription to parent levels, s

262 nario: subjects appeared either unwilling or unable to return the target to their partner.

263 B. was a clinical psychologist who, although unable to return to work, was an active participant in o

264 of patients who were working previously were unable to return to work.

265 ly bulk nature of these techniques, they are unable to reveal the subpopulation variation in EET or l

266 Here we report that LiNO(3), which is unable to ring-open DOL, possesses a previously unknown

267 error correct Rmap data, named cOMet, it is unable to scale to even moderately large sized genomes.

268 xperiences more positively compared to those unable to see facial movements.

269 We were unable to separate the pb-like and zen2-like specificiti

270 ion or expansion of specific regions, and is unable to show additional dimensions of the dataset.

271 -like5 (Dcl5) expression, and dcl5-1 mutants unable to slice PHAS transcripts lack nearly all 24-nt p

272 ndothelial cell-specific Bmpr2-knockout mice unable to stabilize p53 in endothelial cells under oxida

273 increase of APOB-containing lipoproteins is unable to stimulate m-RCT.

274 Peptides that were unable to stimulate PAR4-dependent calcium signaling cou

275 The mutant TRIFs were unable to support STING signaling, although they were fu

276 of patients, the uncommitted precursors were unable to support the constant development of B cells in

277 mics of subtropical coral populations appear unable to support their future persistence under unprece

278 ted compromised virulence functions and were unable to suppress NPR1 accumulation, FLS2 accumulation,

279 eleted for the c-di-AMP cyclase gene dacA is unable to survive in rich medium unless it acquires comp

280 ls in B cell-deficient mice, these mice were unable to survive the infection.

281 Yeast cells unable to synthesize inositol pyrophosphates (PP-InsPs)

282 Animals unable to synthesize or use dopamine lack the conditione

283 Pol, targeting a catalytic metal ligand, was unable to synthesize primers, likely due to protein inst

284 of SLs-and we determined that the mutant was unable to synthesize SLs.

285 orically underrepresented (HU) groups may be unable to take advantage of traditional summer research

286 ches for nanomaterial delivery in plants are unable to target specific subcellular compartments with

287 Captured p65 was unable to translocate to the nucleus or transactivate a

288 strain is restricted to the optic nerve, is unable to translocate to the retina, and causes only min

289 In contrast, CD36(High) LSCs were unable to transplant leukemia but were highly proliferat

290 that colocalize with the channel complex are unable to trigger Ca(2+)-dependent feedback of channel g

291 ulum (ER) stress sensing; however, they were unable to trigger UPR-related transcriptional responses.

292 information intrinsic to the data or iv) are unable to uncover multiple associations between differen

293 iring subsequent ophthalmologist assessment, unable to undergo imaging, and with inadequate images or

294 However, overexpression of IKZF3 was unable to upregulate IL-10 at the mRNA or protein level

295 Cortical neurons are unable to use idebenone as a direct mitochondrial electr

296 Mutants unable to use lactose grew on lactose as the sole carboh

297 ults show that CFS skeletal muscle cells are unable to utilise glucose to the same extent as healthy

298 We were unable to validate previously reported findings of an as

299 ed under real-world clinical conditions, was unable to validate the kSORT assay for detection of AR i

300 nfolding of the Hb heme pocket, leaving IsdH unable to wrest the heme from Hb.