ライフサイエンスコーパス: unanswered

1 lerance results in improved outcomes remains unanswered.

2 ermath of interspecific hybridization remain unanswered.

3 ndamental questions in the field that remain unanswered.

4 n, liver transplantation, and surgery remain unanswered.

5 tion of why they are shaped this way remains unanswered.

6 goes on these femtosecond timescales remains unanswered.

7 effects at the level of freshwater food webs unanswered.

8 ndividual differences have hitherto remained unanswered.

9 ructure and dynamics of PAC1R remain largely unanswered.

10 tream regulation of the 53BP1 pathway remain unanswered.

11 met clinical needs in transplantation remain unanswered.

12 ution for weak selection exists has remained unanswered.

13 The following important questions are still unanswered.

14 is uncertain, and two major questions remain unanswered.

15 ty of mammoth populations and species remain unanswered.

16 functional mapping of microcircuits, remain unanswered.

17 nd possible sites of reactivity has remained unanswered.

18 ong-standing question, which remains largely unanswered.

19 but this model leaves a number of questions unanswered.

20 profoundly, although major questions remain unanswered.

21 yet this important clinical question remains unanswered.

22 elating to sporadic forms of disease, remain unanswered.

23 nts confirmed the former, leaving the latter unanswered.

24 relevance and interaction mechanisms remain unanswered.

25 zoonotic potential, questions that are still unanswered.

26 tion (LT) mortality in cirrhotic patients is unanswered.

27 ssociated VTE, or Trousseau syndrome, remain unanswered.

28 cial status are questions that have remained unanswered.

29 of radiation damage formation remain largely unanswered.

30 estion of their underlying algorithm remains unanswered.

31 sessment, and acute and late effects, remain unanswered.

32 nues for CM, it leaves a number of questions unanswered.

33 hen this function arises and develops remain unanswered.

34 espite this, many important questions remain unanswered.

35 s genesis, fate and evolutionary role remain unanswered.

36 nt in controlling liver regeneration remains unanswered.

37 he present-day Greenlandic population remain unanswered.

38 l, and the case-fatality rate remain largely unanswered.

39 tructural and biochemical transitions remain unanswered.

40 for cells to use either AM or FM is largely unanswered.

41 zation modulate cardiac wave dynamics remain unanswered.

42 anscription, certain questions have remained unanswered.

43 he folding and recognition processes remains unanswered.

44 nt of attention, leaving important questions unanswered.

45 However, many fundamental questions remain unanswered.

46 acity to initiate astrocytic gliomas remains unanswered.

47 srA in B. burgdorferi gene regulation remain unanswered.

48 generated in individual nanocrystals-remains unanswered.

49 istribution and trafficking pathways, remain unanswered.

50 their role in host defense has long remained unanswered.

51 w ER morphology affects this process remains unanswered.

52 driving expansion of the progenitors remain unanswered.

53 of the antibody response to the virus remain unanswered.

54 imes(1,8-10) of ancestral crown birds remain unanswered.

55 routes of propagation and integration remain unanswered.

56 embly prior to proplatelet production remain unanswered.

57 ons pertaining to channel function are still unanswered.

58 hlight several crucial questions that remain unanswered.

59 ghly soluble protein in vivo remains largely unanswered.

60 Hsps interact with misfolded proteins remain unanswered.

61 eir contributions to AMD pathogenesis remain unanswered.

62 ormance; however, many open questions remain unanswered.

63 however, the corresponding questions remain unanswered.

64 fundamental question in evolutionary biology unanswered.

65 wever, many questions regarding ColdU remain unanswered.

66 biological questions about this virus remain unanswered.

67 to chronic conditions in some cases remains unanswered.

68 t five years, but important questions remain unanswered.

69 more of a problem are questions still mostly unanswered.

70 on may affect the feather microbiota remains unanswered.

71 s requires thought and leaves many questions unanswered.

72 ion, in the colon this question has remained unanswered.

73 tive in managing SLE in other organs remains unanswered.

74 enetic architecture across traits, are still unanswered.

75 dslides at margin scale are lacking, leaving unanswered a link between rifting and slope instability.

76 odels exist and fundamental questions remain unanswered, a definitive description of the basic releas

77 t/refractory disease, leaving many questions unanswered about optimal first-line and salvage treatmen

78 of study, many fundamental questions remain unanswered about the dynamics of glass-forming materials

79 However, questions remain unanswered about the impacts of plantations on belowgrou

80 system (CNS), but important questions remain unanswered about the mechanisms controlling these proces

81 een studied intensely, many questions remain unanswered about the microbial metabolism of marine TMA.

82 Many questions remain unanswered about the role of bariatric surgery for peopl

83 t this juncture, while many questions remain unanswered, achievements in several areas of research ha

84 While many scientific questions remain unanswered and new compelling questions will undoubtedly

85 regarding the management of syphilis remain unanswered and should be a priority for future research.

86 eview then outlines important questions left unanswered and suggests future directions for the field.

87 sed on non-carbon frameworks remains largely unanswered, and is an area that potentially provides new

88 the clinic, which important questions remain unanswered, and what future research will be needed to i

89 ents, ought to ensure that the key questions unanswered at the time of drug and device approval are r

90 tions about the domestication process remain unanswered because modern specimens do not represent the

91 This question has remained unanswered because of the rarity of cases of late sight

92 However, many questions remain unanswered because randomized controlled trials are infr

93 This question remains unanswered, because the timescales of coding in populati

94 by organometallic catalysts has remained an unanswered challenge.

95 reatment of older adults with AML or MDS and unanswered clinical questions for older adults with thes

96 al humanitarian and human rights law largely unanswered, despite their enormous consequences.

97 g-standing questions in plant biology remain unanswered due to a lack of technology that precisely de

98 basic questions about its life cycle remain unanswered due to an historical lack of robust experimen

99 d expanding area of research comprising many unanswered fundamental questions.

100 t most synapses in V1 are excitatory leaving unanswered how they change.

101 ntext are two critical questions that remain unanswered in the molecular pathogenesis of FRDA.

102 rk for exploring major questions that remain unanswered, including the origin of jaws.

103 nd modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs

104 Many fundamental questions about EBS remain unanswered, including the spatial extent of cortex respo

105 However, fundamental questions remain unanswered, including the temporal requirements for beta

106 Nevertheless, important questions remain unanswered, including what specific interactions stabili

107 ons about the biology of this disease remain unanswered, investigations of ALS genes have delineated

108 A key question that has remained unanswered is at which step of the assembly line mechani

109 One question that remains largely unanswered is how genetic susceptibility contributes to

110 d results of ancillary investigations remain unanswered, likely leading to incomplete recognition and

111 g intracellular stresses, questions remained unanswered on the intricacies of how cells use such stre

112 ogical function, many basic questions remain unanswered on the morphology and segregation of chromoso

113 rections and questions that currently remain unanswered on the role of Activin/Nodal signalling in st

114 Although many questions remain unanswered, one superantigen-like modality features inte

115 highlight mechanistic questions that remain unanswered or controversial.

116 fy task demands is a controversial and still-unanswered possibility.

117 However, many intriguing questions remain unanswered: Principally, how aggressively should the cli

118 One important but largely unanswered question about floristic responses to climate

119 ired bona fide neuronal subgroups remains an unanswered question and one important for validating ste

120 A major unanswered question concerns the mechanism by which the

121 ermanent microbial habitat; thus, an age-old unanswered question concerns the origin of fruit and fer

122 emokine recognition has been a long-standing unanswered question due to the challenges of structure d

123 A major unanswered question in biology and medicine is the mecha

124 ogress to clinical relevance remains a major unanswered question in cancer biology.

125 An important unanswered question in chromatin biology is the extent t

126 An unanswered question in developmental physiology is to wh

127 efits of biodiversity remain a critical, but unanswered question in ecology.

128 An unanswered question in neuroscience concerns which dimen

129 both mechanisms is required, has remained an unanswered question in radiation belt physics.

130 A key unanswered question in SCA3 and other polyglutamine dise

131 An essential unanswered question in the design of carbon monoxide rel

132 A major unanswered question in the field is how expression of th

133 fall experiences booms and busts, remains an unanswered question in the field of global change biolog

134 This has become a long-standing unanswered question in the fragile X field, which is als

135 ifying a suitable mechanism has become a key unanswered question in the origin of life.

136 An unanswered question in the SMR field is how the dimeriza

137 One unanswered question is how infection is controlled and c

138 An unanswered question is how polar septation activates a t

139 Yet an unanswered question is how the transfer of information b

140 le reduction of pain is important, a largely unanswered question is what other benefits NGF blockade

141 An unanswered question is whether an altered repertoire of

142 A key unanswered question is whether infection with SARS-CoV-2

143 A longstanding, unanswered question is whether nuclear organization is s

144 However, a key unanswered question is whether sparing or sharing farmin

145 A key unanswered question is whether systemic GM-CSF (sargramo

146 A more basic, yet unanswered question is whether the Met(20) loop adopts a

147 A critical unanswered question is whether the MinION and its protei

148 A long-unanswered question is whether these local transient hem

149 However, a critical and largely unanswered question is whether these models generalize f

150 One key unanswered question is whether we can select for a plant

151 Therefore, an unanswered question is why a current/former smoker of ab

152 dian homeostasis in other tissues remains an unanswered question of conceptual and biomedical importa

153 controls these logical processes remains an unanswered question that has been merely superficially a

154 ese activities and loop formation is another unanswered question that should keep investigators occup

155 acity electrodes with anionic redox, a still unanswered question was remaining regarding the importan

156 A very important unanswered question, especially in the very elderly, is

157 are dynamic on short time scales remains an unanswered question.

158 ong the reaction coordinate is a fundamental unanswered question.

159 regulation of FAHFAs remains a pressing but unanswered question.

160 imes has multiple discharges to ground is an unanswered question.

161 ISA from the vast molecular space remains an unanswered question.

162 ain access to chromatin remains an important unanswered question.

163 osin II within the animal cell CR remains an unanswered question.

164 hich variants lead to CKD remains a critical unanswered question.

165 tream at the ERC or remains segregated is an unanswered question.

166 occurred during planet formation remains an unanswered question.

167 evolved endothermy remains an important but unanswered question.

168 elerated to relativistic energies remains an unanswered question.

169 ithin an intact epithelium is a central, yet unanswered question.

170 how important this constraint is remains an unanswered question.

171 mmit to differentiation is a fundamental yet unanswered question.

172 allo-sensitization is a clinically important unanswered question.

173 in a rational, bottom-up manner is a largely unanswered question.

174 it can be adopted at target hospitals is an unanswered question.

175 ces its post-saccadic processing is still an unanswered question.

176 plan is programmed remains a fundamental yet unanswered question.

177 transport and cargo export, is a fundamental unanswered question.

178 e affected, and how many, remains a critical unanswered question.

179 wever, the field is grappling with a central unanswered question: what exactly is a cell type?

180 onse rate (95.85%) and the low percentage of unanswered questions (0.4-2.7%).

181 d host defence mechanisms, there remain many unanswered questions about fundamental processes involve

182 ed the field forward, and summarize some key unanswered questions about koniocellular pathways.

183 spite decades of study, there are still many unanswered questions about metastasis, the process by wh

184 There are many unanswered questions about the environmental fate and me

185 There are many unanswered questions about the evolution of the ancient

186 However, there remain unanswered questions about the mechanism of channel open

187 There are many unanswered questions about the population history of the

188 lene play critical roles but there are still unanswered questions about these and other TFs.

189 The review identifies important unanswered questions about these cells regarding their o

190 To resolve unanswered questions about these inhibitors, we develope

191 We highlight unanswered questions about this remarkable cellular stru

192 A number of unanswered questions and challenges remain, such as how

193 future directions for inquiry, highlighting unanswered questions and conceptual issues concerning ho

194 e initiation and progression, there are many unanswered questions and emerging facets of miRNA biolog

195 ut not supported by recent data, and discuss unanswered questions and future directions for research.

196 ew therapeutics and vaccines, and highlights unanswered questions and priorities for research, improv

197 nsequences, diagnosis and treatment), define unanswered questions and provide a road map toward their

198 atients who die in the ICU often remain with unanswered questions and suffer from lack of closure.

199 ese neuropeptides and outlines the important unanswered questions and testable hypotheses.

200 Important unanswered questions are whether TRPV1(+) neuron activat

201 Here we detail recent advances and unanswered questions at the intersection between inflamm

202 Major unanswered questions concern the nature of the endogenou

203 ess could be adaptive in vivo, are two major unanswered questions concerning this process.

204 ymmetric gut morphogenesis and highlight key unanswered questions for future investigation.

205 ically ill adults and highlights fundamental unanswered questions for future research about fluid the

206 renal disease are discussed, and we explore unanswered questions for future research.

207 on these factors, and to highlight important unanswered questions for the field.

208 Yet, the breadth of important unanswered questions in ccRCC research far exceeds the a

209 to begin to address some of the fundamental unanswered questions in epilepsy, to dissect epileptic n

210 One of the major unanswered questions in evolutionary biology is when and

211 One of the critical unanswered questions in genome biophysics is how the pri

212 th state-of-the-art genetic tools to address unanswered questions in melanoma in vivo See related com

213 discussed the current state of knowledge and unanswered questions in order to propose therapeutic app

214 definition and back-splicing are fundamental unanswered questions in pre-mRNA splicing.

215 icle concludes with an overview of important unanswered questions in SSc research that might inform t

216 ene promoters they control, and we highlight unanswered questions in the field, such as the potential

217 these areas and conclude with challenges and unanswered questions in the field.

218 tive, we highlight recent advances and major unanswered questions in the realm of bacterial vector-bo

219 l of providing insights into some of the key unanswered questions in this field.

220 te and efficiently identify solutions to the unanswered questions in urology cancer care.

221 This review discusses key unanswered questions in ZIKV immunity and in the pathoge

222 Unanswered questions include those relating to the diver

223 identify recent evidence in order to address unanswered questions including the accuracy and effectiv

224 itophagy to neurodegenerative processes, and unanswered questions inspiring future research that woul

225 s context, one of the most important and yet unanswered questions is whether and how HNO is produced

226 Nevertheless, unanswered questions need to be addressed in clinical tr

227 acute diarrheal disease, yet there are many unanswered questions on norovirus immunity, particularly

228 known about ColdU, and we present important unanswered questions on the epidemiology, underlying pat

229 We pose unanswered questions regarding HCC susceptibility and pa

230 gaps in current knowledge and focused on the unanswered questions regarding pulmonary AMR.

231 Unanswered questions regarding RSV epidemiology need to

232 eview will discuss current knowledge and key unanswered questions regarding the blood-brain barrier i

233 We also discuss major unanswered questions regarding the role that defects in

234 However, there are several unanswered questions regarding the sources of Earth's vo

235 ve evolutionary approaches, we discuss major unanswered questions regarding their functional and comp

236 Unanswered questions remain about how common chronic rar

237 air deficient (MMRD) solid tumors, important unanswered questions remain about the role of immune che

238 late (OCP)(-) is not well explored, and many unanswered questions remain about this ligand in this co

239 broad literature describing p53 binding DNA, unanswered questions remain, due partly to the need for

240 nterconnected pathways, and identify the key unanswered questions remaining in this field.

241 tically ill patients, presents the facts and unanswered questions surrounding gut-derived sepsis, and

242 Here, we review the available data and unanswered questions surrounding hospital-acquired pneum

243 There remain unanswered questions surrounding surgical checklists as

244 ns from a structural prospective and discuss unanswered questions surrounding this fascinating class

245 y and immunodeficiency, and pose a series of unanswered questions that are expected to be central in

246 There are still many unanswered questions that challenge our understanding of

247 timing of ERK activation remain fundamental unanswered questions that limit understanding of how arr

248 areas of analysis to explore the expanse of unanswered questions that remain regarding the phenomena

249 fic agent and this one trial or the numerous unanswered questions that remain, BETs have emerged as n

250 to modulate the microbiome, and present key unanswered questions to be addressed in ongoing and futu

251 mitochondrial dynamics emerged and consider unanswered questions whose dissection might lead to mito

252 ssue of the JCI, identify a number of as yet unanswered questions, and discuss some of the therapeuti

253 Here, we analyze the recent advances, unanswered questions, and potential of BacNa(V)s as temp

254 lance, 5) interventions, and 6) limitations, unanswered questions, and resource and policy needs.

255 st research effort, guided by a focus on key unanswered questions, has the potential to yield high-im

256 This mutant enables new research into unanswered questions, including the existence of potenti

257 dard and novel therapies are promising, many unanswered questions, such as duration of therapy and op

258 ctions control mitosis, as well as important unanswered questions.

259 remains unclear, with several long-standing unanswered questions.

260 the need of studies aimed to answer multiple unanswered questions.

261 xisting conditions are important and largely unanswered questions.

262 ecent advances in this area and identify key unanswered questions.

263 marize the recent advances and highlight key unanswered questions.

264 ea, highlighting key findings and some major unanswered questions.

265 G-specific function and articulate important unanswered questions.

266 impacts early development remain important, unanswered questions.

267 tenuate or augment lifespan remain important unanswered questions.

268 and molecular biology tools to explore many unanswered questions.

269 and proliferation of cells remain important unanswered questions.

270 nization of the chromatin all remain largely unanswered questions.

271 own and knockout murine phenotypes have left unanswered questions.

272 to advance this research field and describe unanswered questions.

273 for clinicians and patients alike, with many unanswered questions.

274 repair and stimulate further thought on many unanswered questions.

275 different species and highlighting important unanswered questions.

276 ble of tumor initiation raised two important unanswered questions: how do PGCCs acquire such stemness

277 making it possible to begin to address major unanswered questions: the extent of natural methylation

278 reinhardtii, and many questions still remain unanswered regarding both the regulation of these acclim

279 Critical clinical questions remain unanswered regarding diagnosis and management of patient

280 Many questions remain unanswered regarding how genes and circuits within these

281 past few decades, yet many questions remain unanswered regarding patterns in their biodiversity at l

282 rning differentiation, many questions remain unanswered regarding the involvement of post-transcripti

283 er, a number of fundamental questions remain unanswered regarding the mechanisms by which rapamycin m

284 This review focuses on the major unanswered research questions related to rabies virus pa

285 their efficacy and safety data, highlighting unanswered research questions.

286 Nutrition presents unanswered scientific questions of high public health im

287 At this time, given the nature and number of unanswered scientific, ethical, and policy questions, it

288 Unanswered scientific/technological questions are identi

289 y folded and left many substantial questions unanswered, such as a detailed description of the tertia

290 ifficulties mean that basic questions remain unanswered, such as whether so-called diffusionless soli

291 This lack of neurogenesis leaves unanswered the question of how enteric neuronal populati

292 in the pathogenesis of Chagas disease remain unanswered, the development of autoimmune responses duri

293 Although many questions remain unanswered, the evidence suggests that this treatment mi

294 lia and their roles in human diseases remain unanswered, the prospect of targeting microglia for the

295 nucleus is an age-old question that remains unanswered today.

296 lth of attention, a central question remains unanswered: "What regulates flux through this pathway in

297 pe of allele (i.e., A vs. G), and it remains unanswered whether such an interaction presents at an ea

298 of synapses in V1 are excitatory, it remains unanswered whether the majority of synapses regulating e

299 But the question remains unanswered: why has only the 2,4-isomer emerged as a lab

300 Important questions have remained unanswered: why some patients develop severe disease, wh