ライフサイエンスコーパス: uncaging of

1 Furthermore, uncaging of 1,5-(PP)(2)-InsP(4) but not 3,5-(PP)(2)-InsP

2 ngs, elevation of intracellular Ca(2+) by UV uncaging of 1-(4,5-dimethoxy-2-nitrophenyl)-EDTA-potenti

3 After uncaging of 2-AG, we monitored calcium levels, CB1-GIRK

4 On the other hand, two-photon uncaging of 4-methoxy-7-nitroindolinyl-caged L-glutamate

5 ty that kills cancer cells via photochemical uncaging of a cytotoxic drug.

6 ventricles of live zebrafish by means of the uncaging of a fluorescein derivative.

7 small groups of cells in this area by laser uncaging of a fluorescent dextran, and then tracked thei

8 membrane-associated dimeric protein with the uncaging of a powerful cytotoxic.

9 f techniques by demonstrating the mechanical uncaging of a reactive species within a single protein.

10 ances the templated reaction and enables the uncaging of a substrate.

11 ontrollable strategy via the photo-patterned uncaging of an o-nitrobenzyl-caged fluorescein conjugate

12 a rapid decrease in pH that accompanies the "uncaging" of an effector molecule from o-nitrobenzaldehy

13 Photochemical uncaging of bio-active molecules was introduced in 1977,

14 Photochemical release (uncaging) of bioactive messengers with three-dimensional

15 Uncaging of bis-CNB-GABA evokes inward GABAergic current

16 Localized photolytic uncaging of Ca(2+) from o-nitrophenyl-EGTA in somatic ER

17 r NP-EGTA, the UV flash photolysis-catalysed uncaging of Ca(2+) generated CICR in only 9% of the beta

18 hondria were activated specifically by local uncaging of Ca(2+) in the nucleus.

19 c myocytes, where either one- and two-photon uncaging of Ca(2+) induced highly local or cell-wide phy

20 Here, we utilize the photo-uncaging of Ca(2+) with CaV 2.1 channels fluxing Li(+) c

21 nd FAK inhibits repulsive turning from focal uncaging of Ca(2+) within filopodia.

22 thereby allowing CICR to be generated by the uncaging of Ca2+ (UV flash photolysis).

23 Because the uncaging of Ca2+ fails to stimulate CICR in the absence

24 In the apical region, local uncaging of Ca2+ was able to trigger a CICR wave, which

25 glucose or high K+ stimulation or the global uncaging of Ca2+, we show granule fusion consistently fo

26 is retraction was prevented locally by focal uncaging of caged Ca(2+) that triggered Ca(2+) release f

27 f intact pancreatic acinar cells using local uncaging of caged Ca2+.

28 y carbacyclin-stimulated elevations in cAMP, uncaging of cAMP or exposure to a high concentration of

29 Rapid uncaging of Co(2+) ions by patterned UV light activates

30 eriments, primarily on M4-ipRGCs, with photo-uncaging of cyclic nucleotides and virally expressed CNG

31 an be patterned with dienophiles upon 365 nm uncaging of cyclopentadiene.

32 photon active at 720 nm, optically selective uncaging of DEAC450-caged biomolecules at 900 nm may all

33 Two-photon uncaging of DEAC450-Glu at 900 nm at spine heads on pyra

34 The synthesis and uncaging of dendrimer- and polymeric bead-based model sy

35 t of nanobodies allows high-resolution photo-uncaging of different cell types in areas of interest.

36 Uncaging of DMn is considerably faster, but DMn has a si

37 ution using optically independent two-photon uncaging of each neurotransmitter.

38 exhibited direct (non-synaptic) responses to uncaging of excitatory and inhibitory transmitters.

39 Two-photon uncaging of fluorescein near nonsuperfused gastric surfa

40 recordings, activation of GABAARs, either by uncaging of GABA or by optogenetic stimulation of GABAer

41 Using uncaging of GABA, there is a decreasing GABAergic influe

42 his electrical filtering, we used two-photon uncaging of glutamate and compared the integration of el

43 photon imaging, optogenetics, and dual-color uncaging of glutamate and GABA, we demonstrate that plat

44 t is accomplished using UV laser-based photo-uncaging of glutamate and imaging neuronal activation by

45 rat brain (both sexes) by pairing two-photon uncaging of glutamate at spines and APs evoked by somati

46 that unitary-like activation via two-photon uncaging of glutamate causes GC spines to release GABA b

47 Laser-scanning photo-uncaging of glutamate focally activated neurons in layer

48 d two recently developed methods, two-photon uncaging of glutamate for determining the EPSC of indivi

49 ly different methods: (i) UV light-triggered uncaging of glutamate in intact cells or (ii) piezo-driv

50 Moreover, activation of MOPP cells by focal uncaging of glutamate induced strong inhibition of granu

51 dings of somatic depolarizations elicited by uncaging of glutamate on dendritic fragments, and, in ne

52 Using two-photon uncaging of glutamate on spine heads from mouse layer-5

53 ) on depolarizations generated by two-photon uncaging of glutamate on spines from mouse neocortical p

54 ut screening method exploiting laser-induced uncaging of glutamate to construct excitatory input maps

55 Here, we use two-photon laser uncaging of glutamate to directly activate glutamate rec

56 Here we employed optical uncaging of glutamate to mimic synaptic excitation of di

57 Focal uncaging of glutamate, accomplished by switching a pulse

58 hoton laser scanning microscopy and 2-photon uncaging of glutamate, Carter and Sabatini (this issue o

59 ation of EPSPs, generated through two-photon uncaging of glutamate, this action was largely shunted b

60 ser scanning microscopy and two-photon laser uncaging of glutamate, we show that SK channels regulate

61 ser-scanning microscopy and two-photon laser uncaging of glutamate.

62 g iontophoresis of l-aspartate or two-photon uncaging of glutamate.

63 Uncaging of glycerophosphoryl-myo-inositol 4,5-bisphosph

64 lipo-Pd@Au nanorods is able to catalyze the uncaging of inactive drug precursors and release heat to

65 ereas postsynaptic stores (activated by spot-uncaging of inositol 1,4,5-trisphosphate) remain unaffec

66 ith UDP-GlcNAc had an attenuated response to uncaging of InsP3.

67 eover, the Ca(2+) responses to melatonin and uncaging of IP(3) were mutually exclusive in infected RB

68 Photo-uncaging of IP3 in neurons expressing PI3K* elicits a ma

69 ow-intensity tetanic synaptic stimulation or uncaging of IP3 increased the decay time of spontaneous

70 On uncaging of IP3, astrocyte Ca2+ responses reliably propa

71 Furthermore, uncaging of MNI glutamate reveals that thalamocortical n

72 Two-photon (2P) uncaging of MNI-glutamate onto individual spines suggest

73 ary spatiotemporal pattern, using two-photon uncaging of MNI-glutamate with beam multiplexing.

74 Local photo-uncaging of oxymorphone in the DRN produced conditioned

75 Photolytic uncaging of p-hydroxyphenacyl (pHP) GABA demonstrates ba

76 of presynaptic GABA receptors by photolytic uncaging of RuBi-GABA has a biphasic effect on EPSC ampl

77 (520 mum) by excitability testing and focal uncaging of RuBi-GABA on the axon at varying distances f

78 patch clamp electrophysiology and photolytic uncaging of RuBi-GABA we show that GABA(B) receptors are

79 le-cell patch-clamp recording and photolytic uncaging of RuBi-GABA.

80 nitrodibenzofuran (NDBF) for ultra-efficient uncaging of second messengers inside cells.

81 Thus, optical uncaging of signaling lipids can uncover their rapid eff

82 ne include the bioluminescence-induced photo-uncaging of small-molecules, bioluminescence based photo

83 Further, uncaging of Sph leads to the translocation of the autoph

84 micropatterns by means of photolithographic uncaging of surface amines.

85 on of the lipid derivatives before and after uncaging of the lipids.

86 on as well as pinpoint the location at which uncaging of the molecules occurred.

87 Light-driven uncaging of the photolabile calcium chelator DMNP-EDTA s

88 aling lipids sphingosine and diacylglycerol; uncaging of the probe for these two species triggered ca

89 In addition, through uncaging of the same compound, gene expression is contro

90 Finally, uncaging of these protected peptides by either UV or two