ライフサイエンスコーパス: unconjugated

1 ely 65% was conjugated and approximately 35% unconjugated.

2 Unconjugated 7E4B11 provides a modest but statistically

3 the simple addition of an anti-fluorochrome unconjugated Ab during staining resulted in considerably

4 dge, we show for the first time that whereas unconjugated Ab plus siRNAs reduce arthritis by 19%, our

5 ELISA analysis showed that the unconjugated Ab, polymer-Ab conjugates, and Ab-labeled D

6 is required to develop optimized therapeutic unconjugated Abs.

7 s in tumors is 4- to 15-fold higher than for unconjugated ACPPs.

8 lfate esters, extraction, and dansylation of unconjugated aglycones were tested and optimized.

9 thod available for the photocycloaddition of unconjugated aliphatic alkenes is the Cu-catalyzed Salom

10 can also reduce nitriles in the presence of unconjugated alkenes and alkynes such as the reduction o

11 Unconjugated all-trans-retinal dimer was a more efficien

12 ts, all-trans-retinal dimer-ethanolamine and unconjugated all-trans-retinal dimer, in human and mouse

13 A novel rearrangement reaction of the unconjugated allylic amine Petasis reaction product to a

14 its affinity for TAR in vitro similar to the unconjugated analog.

15 Both unconjugated and conjugated antibodies show significant

16 arameters were significantly correlated with unconjugated and conjugated bilirubin and INR (p < 0.05)

17 xtinction coefficients and dn/dc values both unconjugated and conjugated protein molecules.

18 specific IgGs with selective antibody pairs [unconjugated and conjugated with horseradish peroxidase

19 associated with markedly elevated levels of unconjugated and glycine-conjugated bile acids in gallbl

20 estinal tract of ethanol-treated rats, while unconjugated and glycine-conjugated species increased.

21 Unconjugated and primary BA in serum and faeces were sig

22 Endogenous levels of the unconjugated and sulfated steroids were detected and qua

23 used to examine quantitatively the extracted unconjugated and sulfated steroids, where the recovery e

24 r measuring the absolute quantities of free (unconjugated) and total (conjugated + unconjugated) endo

25 Total (conjugated plus unconjugated) and unconjugated levels of these steroid h

26 , the majority of gallbladder bile acids was unconjugated, and only a small percentage was conjugated

27 The second most abundant unconjugated androgen produced by the human adrenals is

28 3-conjugated dexamethasone (0.005 mg/kg); 6) unconjugated anti-CD163.

29 Combining an unconjugated anti-CD20 antibody therapy with a radioimmu

30 Unconjugated anti-PSCA antibodies demonstrated efficacy

31 Antibody-based therapies, both unconjugated antibodies and radioimmunotherapy, have had

32 Unconjugated antibodies show significant efficacy in the

33 None of the unconjugated antibodies was effective against establishe

34 The unconjugated antibody (MLN591) demonstrated essentially

35 to evaluate whether co-administration of an unconjugated antibody could improve the intratumoral dis

36 ituximab into clinical practice as the first unconjugated antibody for cancer treatment, underscoring

37 Promising new targets for unconjugated antibody therapy include cellular growth fa

38 We evaluated a predosing strategy with unconjugated antibody to block ADC uptake in target-expr

39 iation and having therapeutic activity as an unconjugated antibody, protected mice for only 30 days;

40 c IgA titre in the female genital tract than unconjugated antigen.

41 ained after the administration of either the unconjugated antiluciferase PNA or a PNA conjugate that

42 Both uptake and correction were inhibited by unconjugated aptamer, confirming the role of the aptamer

43 The unconjugated ASOs are currently in late stage clinical t

44 he loss of activity of GalNAc conjugated and unconjugated ASOs in ASGR knockout mice.

45 ncement in the muscle of rodents relative to unconjugated ASOs.

46 After HC diet, the level of unconjugated BA decreased [0.92 +/- 0.55 mumol/L to 0.32

47 ol/L to 3.59 +/- 3.70 mumol/L (P = 0.01) and unconjugated BA levels increased from 0.18 +/- 0.24 mumo

48 ereas almost equal amounts of conjugated and unconjugated BAs existed in non-bile reflux and healthy

49 tion revealed selective increases in primary unconjugated BAs in the WD-fed mice, which correlated wi

50 In contrast, the serum concentrations of unconjugated BAs were 3-45 times higher in Oatp1b2-null

51 tion and biliary excretion of conjugated and unconjugated BAs were essentially the same in Oatp1b2-nu

52 s markers and total plasma BAs, particularly unconjugated BAs, had markedly risen; this effect could

53 vious differences between the conjugated and unconjugated BAs.

54 b2 has a major role in the hepatic uptake of unconjugated BAs.

55 There was no neuroprotective effect of the unconjugated BDNF or unconjugated OX26 mAb.

56 MCAO) were treated intravenously with either unconjugated BDNF, unconjugated MAb, or the BDNF-OX26 co

57 the initial nitroaldols dehydrated to afford unconjugated beta,gamma-unsaturated alpha-nitrosulfones

58 Unconjugated bile acids accounted for 95.7% +/- 5.8% of

59 , collectively our findings demonstrate that unconjugated bile acids activate hepatocyte receptor tyr

60 In mice, unconjugated bile acids are conjugated with taurine by t

61 98.3%), duodenum (97.8%), and ileum (89.7%), unconjugated bile acids comprised the largest proportion

62 ice accumulated high levels of predominantly unconjugated bile acids in plasma because of altered exp

63 (ERK)1/2 and AKT pathways by conjugated and unconjugated bile acids in primary hepatocytes.

64 Increased amounts of total and unconjugated bile acids in the faeces of the probiotic-f

65 Unconjugated bile acids must be activated to their CoA t

66 cal lithocholic acid (p < 0.0001), with more unconjugated bile acids than women with untreated ICP or

67 Faecal extracts contain several unconjugated bile acids that cause concentration-depende

68 Unconjugated bile acids were about fivefold more potent

69 Significant amounts of unconjugated bile acids were also found in the liver and

70 However, the levels of unconjugated bile acids-generated by bacterial bile salt

71 with respect to this mutation contains only unconjugated bile acids.

72 ate and taurocholate) being less active than unconjugated bile salts (deoxycholate and cholate).

73 uction was observed with both conjugated and unconjugated bile salts and was in a dose- and time-depe

74 ux pump by decanoate and the more lipophilic unconjugated bile salts is mediated by Rob, and that the

75 icient mice indicated that hepatic uptake of unconjugated bile salts was strongly impaired whereas up

76 ciency interferes with basolateral uptake of unconjugated bile salts, a process mediated by organic a

77 Decanoate and unconjugated bile salts, which are present in the normal

78 an increase in conjugated, and a decrease in unconjugated, bile acids.

79 patient sera to characterize the binding of unconjugated bilirubin (B(T) ) to albumin (A) and valida

80 0.96 to 5.73, p = 0.06), lower pre-operative unconjugated bilirubin (HR: 0.84 mumol/l, 95% CI: 0.72 t

81 High levels of unconjugated bilirubin (UCB) in newborn children is asso

82 atabolism, indirectly reflecting in elevated unconjugated bilirubin (UCB; main phenotypic feature of

83 Unconjugated bilirubin and ammonia were or tended to be

84 r investigate the toxicities associated with unconjugated bilirubin and the impact of this disease in

85 e findings indicate that elevations in serum-unconjugated bilirubin associated with indinavir treatme

86 ositive or HCV-negative specimens except for unconjugated bilirubin at concentrations of >or=20 mg/dl

87 The unbound unconjugated bilirubin concentration by the combined met

88 with that in model vesicles, suggesting that unconjugated bilirubin crosses cellular membranes by pas

89 his enzyme is responsible for elimination of unconjugated bilirubin from the body by glucuronidation.

90 ethod is ideally suited to measuring unbound unconjugated bilirubin in jaundiced human newborns or an

91 The result of extreme unconjugated bilirubin in Ugt1(-/-) mice, comparable to

92 In newborns with CN1, unconjugated bilirubin increased 4.3 +/- 1.1 mg/dL per d

93 orn Ugt1(-/-) mice developed serum levels of unconjugated bilirubin that were 40-60 times higher than

94 The unbound unconjugated bilirubin was an unpredictable fraction of

95 associated with significant exacerbation of unconjugated bilirubin which persisted through pregnancy

96 bilirubinemia, caused by the accumulation of unconjugated bilirubin, is one of the most common clinic

97 ponsible for the clearance and metabolism of unconjugated bilirubin, the hydrophobic end-product of h

98 , FLVCR has a narrow substrate range because unconjugated bilirubin, the primary breakdown product of

99 a diazo method for measuring conjugated and unconjugated bilirubin.

100 lirubin conjugation could increase levels of unconjugated bilirubin; the effects can be benign and fr

101 welve subjects with GS developed significant unconjugated bilirubinemia during direct antiviral thera

102 posure and may lead to higher proportions of unconjugated BPA in systemic circulation.

103 Unconjugated BPA levels in exposed dams and fetuses (ges

104 term, which resulted in 0.68 +/- 0.312 ng of unconjugated BPA per mL of maternal serum, a level compa

105 Total and unconjugated BPA were detected in sera from 100% of dams

106 ams, fetuses, and nursing pups for total and unconjugated BPA.

107 ulting mean internal cumulative exposures to unconjugated BPs were 3.8 and 2.1 ng/kg bw/day before an

108 We calculated internal concentrations of unconjugated BPs with substance-specific PBPK models and

109 yer movement differed between conjugated and unconjugated BSs as determined with Laurdan-labeled lipo

110 In contrast, free CoA, like unconjugated butyrate, inhibits HDAC activity in vitro.

111 In contrast, unconjugated CalichDMH, unconjugated G5/44, and an isoty

112 rience a change in regioselectivity and form unconjugated carboxylic acids.

113 Immunotherapy with unconjugated CD20 monoclonal antibodies has proven effec

114 rs this interaction by 50-fold compared with unconjugated CDC34.

115 deoxycholic, cholic, and deoxycholic acid in unconjugated (CDCA, CA, and DCA) and tauro-conjugated (t

116 lete Freund's adjuvant more effectively than unconjugated CGRP8-37 Our results show that CLR signals

117 CGRP8-37-cholestanol, but not unconjugated CGRP8-37, prevented sustained neuronal exci

118 Unconjugated Ch and CDC (pKa values of approximately 5.0

119 NASH had higher conjugated to unconjugated chenodeoxycholate (P = 0.04), cholate (P =

120 Neither of the parent compounds, unconjugated Chl or polyamide 1, demonstrated any cellul

121 and bile at baseline revealed predominantly unconjugated cholic acid and absence of the usual glycin

122 Unconjugated cholic acid continued to be present in high

123 nt samples and serum contained predominantly unconjugated cholic acid.

124 plex increases specificity 150-fold over the unconjugated complex.

125 model of E7-expressing lung cancer than its unconjugated components.

126 retained hFcRn engagement compared with a WT unconjugated control demonstrated by Biolayer Interferom

127 gher anti-LPS IgG levels than mice receiving unconjugated COPS and exhibited high antiflagellin IgG;

128 been quantified after being converted to its unconjugated counterpart by sulfatase/glucuronidase.

129 lying the efficacy of the conjugate over its unconjugated counterpart have been largely uninvestigate

130 rongly than did their more membrane-permeant unconjugated counterparts, suggesting that bile acids re

131 ects of drug-conjugated peptides compared to unconjugated counterparts.

132 excretion dynamics of polymer-conjugated and unconjugated CPT appear similar between animals and huma

133 Plasma concentrations of unconjugated CPT released from CRLX101 in animals and hu

134 Unconjugated CRM(197) and serotype conjugates 14 and 18C

135 The animal receiving unconjugated CRM9 exhibited the same neurotoxic side eff

136 Unconjugated CRM9 was administered to one animal to defi

137 These results indicate that unconjugated cytosolic OVA is not stably expressed in Pl

138 ying enzymes, which leads to accumulation of unconjugated cytotoxins and carcinogens in the bladder.

139 In contrast to unconjugated D2B or vehicle, treatment with either of th

140 tion was also evidenced by the fact that the unconjugated drug (desacetylvinblastine monohydrazide) w

141 ering the drug at a much lower dose than the unconjugated drug injected systemically to effectively i

142 eutic index of DDCs was 2-3-fold higher than unconjugated drugs.

143 d growth-inhibitory activity compared to the unconjugated drugs; sites of alkylation at tracts of mul

144 ing a variety of functionality, including an unconjugated (E,Z) diene, are reported.

145 quitin complex and subsequent release of the unconjugated E2 protein upon ubiquitin transfer to a sub

146 ce for EhUba1 approximately Ub compared with unconjugated EhUba1.

147 Active transport of conjugated and unconjugated electrophiles out of cells is essential for

148 PBS and unconjugated ELIPs were controls.

149 free (unconjugated) and total (conjugated + unconjugated) endogenous estrogens and estrogen metaboli

150 (4-OT), a homohexameric enzyme, converts the unconjugated enone, 2-oxo-4-hexenedioate (1), to the con

151 was approximately equal to that reported for unconjugated Epo delivered s.c. in humans.

152 protein, total human chorionic gonadotropin, unconjugated estriol, and inhibin A at 15 through 18 wee

153 assayed plasma concentrations of estradiol, unconjugated estriol, testosterone, progesterone, prolac

154 (DI-SPME- HPLC-ESI -MS) for determination of unconjugated fatty acids (FA) in fish and human plasma.

155 sion analysis (TDA), showed a 92% removal of unconjugated FITC (FITC clearance: 92%, RSD: 3%), while

156 Negatively charged and unconjugated FITC was extracted electrokinetically into

157 initial research on feasibility, removal of unconjugated fluorescein isothiocyanate (FITC) after flu

158 tula rats, sulindac was recovered in bile in unconjugated form and induced hypercholeresis of canalic

159 of target proteins, ISG15 can be found in an unconjugated form both inside of the cell and released f

160 red light-activated (Pfr) or the chromophore unconjugated form of the enzyme.

161 ge 1.8-3.0), consisting predominantly of the unconjugated form; that of the control patients was 0.76

162 resis when secreted into canalicular bile in unconjugated form; the mechanism is cholehepatic shuntin

163 - 248 mumol/L) and predominantly excreted in unconjugated forms (79.4% +/- 3.9%) and as sulfates and

164 n their conjugated (glycine and taurine) and unconjugated forms was monitored by isothermal titration

165 (ng/mL) and 0.005 to 0.017 ng/mL for "free" (unconjugated forms) and "total" (unconjugated plus conju

166 A method is described for measuring the unconjugated fraction of the unbound bilirubin concentra

167 e nontoxic but may hydrolyze to their potent unconjugated, 'free' forms.

168 and extracted with hexane to separate free (unconjugated) from sulfated steroids.

169 Both CMC-544 and unconjugated G5/44 bound human CD22 with subnanomolar af

170 In contrast, unconjugated CalichDMH, unconjugated G5/44, and an isotype-matched control conju

171 CMC-544, but not unconjugated G5/44, exerted potent cytotoxicity against

172 The plasma percentages of unconjugated genistein concentrations in Sprague-Dawley

173 The proportion of unconjugated genistein in plasma from adults and infants

174 We conducted safety studies of purified unconjugated genistein, daidzein, and glycitein, and def

175 ating concentrations of biologically active (unconjugated) genistein in certain strains of mice cast

176 In contrast, unconjugated GFP in the mitochondrial matrix (targeted u

177 gosaccharides (HMOs) are a family of diverse unconjugated glycans that exist in human milk as one of

178 d inducing HDR, with cationic polymers, than unconjugated gRNA and donor DNA.

179 We evaluated sera from women immunized with unconjugated group B streptococcal (GBS) type III (GBS I

180 Unconjugated HPODEs are unique products of singlet oxyge

181 were readily removed, and the two remaining unconjugated HPODEs could then be easily isolated regioi

182 Lintuzumab (HuM195) is an unconjugated humanized murine monoclonal antibody direct

183 e oligomerization and albumin-binding of the unconjugated hybrid peptide as well as its lipidated var

184 intestine and liver resulting in a smaller, unconjugated hydrophobic bile acid pool.

185 bilirubin metabolism, characterised by mild, unconjugated hyperbilirubinaemia.

186 y inherited disorder characterized by severe unconjugated hyperbilirubinemia caused by a deficiency o

187 Unconjugated hyperbilirubinemia develops in up to 25% of

188 Severe unconjugated hyperbilirubinemia in humans that suffer fr

189 by the donor liver and present with isolated unconjugated hyperbilirubinemia in liver transplant reci

190 ansplant Clinic, five patients with isolated unconjugated hyperbilirubinemia in the absence of hemoly

191 Jaundice resulting from unconjugated hyperbilirubinemia is easily treated with e

192 r-Najjar syndrome type I is characterized by unconjugated hyperbilirubinemia resulting from an autoso

193 ndrome (GS) is characterized by intermittent unconjugated hyperbilirubinemia without structural liver

194 disorders, jaundice resulting from isolated unconjugated hyperbilirubinemia, and rash or photosensit

195 pharmacological therapy of life-threatening unconjugated hyperbilirubinemia.

196 holangitis, her blood analysis showed severe unconjugated hyperbilirubinemia.

197 Conjugated hyperbilirubinemia and unconjugated hypercholanemia and loss of OATP expression

198 ed by a conjugated hyperbilirubinemia and an unconjugated hypercholanemia.

199 % tumor growth inhibition compared to 60% by unconjugated Ida alone and led to significant enhancemen

200 vitro cytotoxicity of DDCs was comparable to unconjugated Ida in several sensitive and resistant canc

201 irculation half-life (t(1/2)) by 5-fold over unconjugated Ida.

202 The initial charge heterogeneity of the unconjugated IgG-2 monoclonal antibody (mAb) was assesse

203 5%) such that it was not necessary to remove unconjugated impurities.

204 and selective against hGIIA sPLA(2) than the unconjugated inhibitor.

205 conjugation inhibits many viruses, and free (unconjugated) ISG15 can also act as an antiviral protein

206 fety and pharmacokinetic studies of purified unconjugated isoflavone preparations containing genistei

207 Dietary supplements of purified unconjugated isoflavones administered to humans in singl

208 A single-dose administration of purified unconjugated isoflavones at amounts that exceed normal d

209 that enables simultaneous quantification of unconjugated l-DOPA, catecholamines, and metanephrines i

210 and size exclusion chromatography to remove unconjugated label.

211 ctions with the lipid-conjugated LC3 but not unconjugated LC3.

212 ease digestion, or competition by mannose or unconjugated lectin.

213 Total (conjugated plus unconjugated) and unconjugated levels of these steroid hormones were measu

214 lar linear probe) after injection of saline, unconjugated liposomes and antibody conjugated liposomes

215 The unconjugated LTB4 metabolites found in urine were struct

216 intravenously with either unconjugated BDNF, unconjugated MAb, or the BDNF-OX26 conjugate at a dose o

217 similar in magnitude to those induced by the unconjugated mAb.

218 the same variant population observed on the unconjugated mAb.

219 Unconjugated mAbs have emerged as useful cancer therapeu

220 achieve higher clinical response rates than unconjugated mAbs targeting the same cell surface antige

221 he sensitivity nearly five times higher than unconjugated MBs.

222 ge 13-16 months or 4 years with 10 microg of unconjugated menC polysaccharide.

223 al conjugate vaccine to those elicited by an unconjugated meningococcal polysaccharide vaccine.

224 Unlike an unconjugated miR146a, C-miR146a was rapidly internalized

225 oxic radical AN-201 as single drugs or as an unconjugated mixture) had no significant effects.

226 jor cytotoxic mechanism for both therapeutic unconjugated monoclonal Abs (mAbs) such as rituximab and

227 Unconjugated monoclonal antibodies have emerged as impor

228 Unconjugated monoclonal antibodies that target hematopoi

229 range of monomers, including conjugated and unconjugated monomers, using ultralow concentrations of

230 Initial CDMS analysis of the unconjugated MS2 particles suggested that they had packa

231 many additional contributions on the use of unconjugated "naked" antibodies for the treatment of can

232 Unlike unconjugated nanocrystals, SNACs were found to dose-depe

233 itor of oligomerization of the more abundant unconjugated NP.

234 Conjugated and unconjugated oligomers were tested to determine sequence

235 egradation products of GalNAc conjugated and unconjugated oligonucleotides in target cells.

236 onjugated oligonucleotides is different from unconjugated oligonucleotides, appropriate analytical me

237 The generation of free N-glycans, or unconjugated oligosaccharides derived from N-linked glyc

238 Unconjugated opsin apoproteins act as phospholipid scram

239 sults thus establish biological function for unconjugated opsin apoproteins outside of eyes and, in a

240 ated an antileukemic effect when used either unconjugated or attached to radioactive iodine.

241 eductions in uptake could increase levels of unconjugated or conjugated bilirubin (Rotor syndrome).

242 not depend on whether IIIPS was given in the unconjugated or conjugated form.

243 n was at least 400 times more efficient than unconjugated OVA and, for MHC class I, the DCs had to ex

244 al skin reactions during therapy compared to unconjugated OVA.

245 rotective effect of the unconjugated BDNF or unconjugated OX26 mAb.

246 tic p-cresol sulfate (PCS) but no detectable unconjugated p-cresol.

247 ential for net uptake because neither of the unconjugated parent compounds are accumulated under ener

248 stered weekly subcutaneous injections of the unconjugated parent drug, IONIS-PKK(Rx), for 12 to 16 we

249 incubation of the immune serum with soluble, unconjugated peptide, indicating the specificity of the

250 decreased integrin binding affinity than the unconjugated peptide, it indicated integrin specific acc

251 Compared to unconjugated peptide, the vaccine upregulates expression

252 emagglutinin (HA) and show that although the unconjugated peptides are inactive, the cholesterol-conj

253 small but significant role in the uptake of unconjugated phosphorothioate ASOs into hepatocytes.

254 also appears to play a role in the uptake of unconjugated phosphorothioate modified ASOs in the liver

255 e polyanionic 17.1A chlorin(e6) conjugate or unconjugated photosensitizer.

256 tion in vitro relative to free ovalbumin, an unconjugated physical mixture of ovalbumin and polymer,

257 for "free" (unconjugated forms) and "total" (unconjugated plus conjugated forms) measurements, respec

258 g systemic administration in comparison with unconjugated PMO and other ASO strategies.

259 A 23-valent unconjugated pneumococcal polysaccharide vaccine (23vP),

260 Although the DNA-binding properties of unconjugated polyamides are similar, the alpha-DABA conj

261 compared to adding the same concentration of unconjugated polymer to the protein.

262 Although unconjugated polysaccharide pneumococcal vaccines have d

263 lar antibody in infants and children than do unconjugated polysaccharide vaccines.

264 ee of flexibility - at least as great as the unconjugated polysaccharides, and very different from th

265 e stimulation, ubp3 Delta mutants accumulate unconjugated polyubiquitin chains as well as polyubiquit

266 to improve staining using anti-fluorochrome unconjugated primary Abs followed by secondary staining

267 es can result in a mixture of conjugated and unconjugated products, which are often difficult to sepa

268 The g-factor spectra of 19 soluble, unconjugated proteins of known structures were measured

269 Using these, the g-factor spectra of other unconjugated proteins, measured in solution or as films,

270 Further, compared with unconjugated PT, AuNP-PT was less susceptible to reducti

271 Unconjugated qdots and PEG-qdots that lacked conjugated

272 In contrast, the unconjugated rhDNase was cleared from the lung lumina wi

273 herapy or immunotherapy with the widely used unconjugated rituximab monoclonal antibody (mAb).

274 ompared to direct detection and conventional unconjugated sandwich.

275 renal medullary secretion, we injected DSAP, unconjugated saporin (SAP), or saline bilaterally into t

276 jugated to the mu-opioid agonist dermorphin; unconjugated saporin and dermorphin were used as control

277 before the start of conditioning therapy for unconjugated serum bilirubin concentrations of at least

278 n was shown to reach up to 22 hours, whereas unconjugated single-stranded DNA was degraded within min

279 s at the 2- and 2,7-positions, the typically unconjugated sites in the pyrene framework.

280 10-fold increased and were mostly present as unconjugated species.

281 take and was markedly more effective than an unconjugated SSO or the monovalent conjugate in modifyin

282 Stokes shift and lack of fluorescence in its unconjugated state.

283 MS) for the carbon isotope ratio analysis of unconjugated steroids.

284 s both for conjugated polyhalides as well as unconjugated substrates.

285 We show that unconjugated SUMO levels are largely maintained througho

286 Unconjugated TAMRA was rapidly cleared and did not becom

287 s of glycine- and taurine-conjugated BAs and unconjugated tetra-hydroxy BAs.

288 (followed by long-wave UVA light; 1.2%) and unconjugated TFOs alone (1.0%).

289 ), displayed superior activity compared with unconjugated trastuzumab or trastuzumab linked to other

290 CPS-tetanus toxoid conjugate vaccine and the unconjugated two-repeat alpha C protein, which protected

291 namics and regulation of even free (that is, unconjugated) Ub are poorly understood.

292 oplasmic proteins and increased depletion of unconjugated ubiquitin.

293 Unconjugated, unlabeled antibody was preadministered to

294 This screen revealed a series of physiologic unconjugated urinary catechols that were able to functio

295 Unconjugated ursodiol bypassed the hepatic uptake block

296 In contrast, unconjugated ursodiol entered the liver and was conjugat

297 y of human cell lines over the equivalent of unconjugated vector (aMMLV).

298 GF (100 mug/kg), a matching concentration of unconjugated VEGF (18.65 mug/kg), ELP alone (100 mug/kg)

299 n those observed with placebo, ELP alone, or unconjugated VEGF.

300 of organic anions, including conjugated and unconjugated xenobiotics and bile acids, from the liver.