ライフサイエンスコーパス: uncouple

1 responses to plant genotypic diversity were uncoupled.

2 unctions of T helper cells are biochemically uncoupled.

3 ic switching and transmission competence are uncoupled.

4 ubgenomes of allotetraploid cotton are often uncoupled.

5 nd joint inflammation are at least partially uncoupled.

6 nt RNA and expression of viral replicase are uncoupled.

7 ty, indicating that the two processes can be uncoupled.

8 pagation and toxicity can be mechanistically uncoupled.

9 e apoptosis during adrenergic stimulation of uncoupling.

10 ecreases caloric efficiency by mitochondrial uncoupling.

11 ve rat and SHR vessels, which suggested eNOS uncoupling.

12 ular respiration via increased mitochondrial uncoupling.

13 GENOMES UNCOUPLED 1 (GUN1) is an important regulator of this pat

14 sk factors for experimental food allergy and uncouple a pathogenic role of an HFD-associated microbio

15 unctions that were lost in glaucoma, whereas uncoupled ACs were largely unaffected.

16 consumption rate as an assay for determining uncoupling activity, changes on the 5- and 6-position of

17 Mutations in Ser-23, Lys-148, and Arg-321 uncoupled adenosine triphosphatase and Rca activity, imp

18 that globally targeting mitochondria with an uncoupling agent is unlikely to provide therapeutic bene

19 e stimulation by introducing a mitochondrial uncoupling agent to the microchannel, enabling determina

20 Uncoupled and disorganized bone formation and resorption

21 late unwinding following helicase-polymerase uncoupling and establishment of prolonged stalled fork s

22 mplate aberrations cause helicase-polymerase uncoupling and impede replication fork progression, but

23 se, Pol delta, binds the leading strand upon uncoupling and inhibits TLS.

24 d other proteins indicative of mitochondrial uncoupling and nonshivering adaptive thermogenesis.

25 However, the extent of this uncoupling and the roles of DNA methylation in shaping d

26 t among groups, but markers of mitochondrial uncoupling and thermogenesis (uncoupling protein-1, deio

27 Whether these functions can be uncoupled, and whether mutant proteins retaining partial

28 reased tPA activity, prevented neurovascular uncoupling, and ameliorated cognition in 11- to 12-month

29 We show that when growth and metabolism are uncoupled, antibiotic lethality uniformly depends on the

30 olid organ transplant recipients designed to uncouple antitumor and anti-allograft immunity.

31 tional anti-CTLA4 DVD provides an avenue for uncoupling antitumor efficacy from immunotherapy-induced

32 n being regulated, instead gradually becomes uncoupled as nucleosome sliding reaches an end point and

33 eakage are both prominent but believed to be uncoupled as they occur in separate spatiotemporal patte

34 state connectivity, to explore neurovascular uncoupling as a mechanism underlying these changes, and

35 in D-dependent mitochondrial proton leak and uncoupling as a potentially novel subcellular mechanism

36 ile lipid cycling, rather than mitochondrial uncoupling, as a way to increase energy expenditure in C

37 (HUVECs) treated with dextrin confirmed eNOS uncoupling, as verified by the reduced eNOS dimer/monome

38 ively supercoiled DNA product, but partially uncouples ATP turnover from strand passage, manifesting

39 ctron microscopy structures of a mutant that uncouples ATPase activity from directional movement reve

40 regulator of macroautophagy during mitosis, uncoupling autophagy regulation from nutrient status to

41 L targeting of mitochondria and functionally uncouples BAX clustering from cytochrome c release, whil

42 This temporal uncoupling became larger in short photoperiods and may r

43 tween alphaL alphaI and beta2 betaI could be uncoupled because the beta2 extension and headpiece open

44 Thus, uncoupling between two fundamental physiological paramet

45 plies a selection for aerobic glycolysis and uncoupling biosynthesis from NADH generation.

46 een proposed that AAC mediates mitochondrial uncoupling, but it has proven difficult to demonstrate t

47 ) converted the Mn(2+)/Ca(2+) exchange to an uncoupled channel mode, permeable to both Ca(2+) and Mn(

48 id alternate-access mechanism which mediates uncoupled chloride transport with negligible bicarbonate

49 A polymerase, CMG remains on ssDNA, but when uncoupled, CMG employs this gate to traverse forked junc

50 nteracts with cellulose synthase-microtubule uncoupling (CMU) proteins that are important for the mic

51 parallel across a broad range of coupled and uncoupled conditions to determine their relative contrib

52 circadian-regulated intestinal mitochondrial uncoupling controls longevity in Drosophila and suggest

53 uggests that the H(+) leak and mitochondrial uncoupling could be dynamically controlled by cellular A

54 loss of intestinal stem cells but drives Wnt-uncoupled crypt expansion.

55 s material incorporates crystal defects with uncoupled Cu(II) centres as evidenced by confocal fluore

56 the metal-organic framework film comprising uncoupled Cu(II) centres homogenously distributed throug

57 late the compartment, making it difficult to uncouple cystoprotein function from ciliary localization

58 e consequential complexities associated with uncoupling defence responses.

59 Regression analysis revealed uncoupled development of intrinsic and network excitabil

60 xpected for a process in which mitochondrial uncoupling diminishes ATP production, a mitochondrial pr

61 iferative history through mass cytometry and uncouple division, time and regulatory protein expressio

62 asymmetric or symmetrically methylated DNA, uncouples DNA affinity from regulation of E3 ligase acti

63 Uncoupling DNA demethylation from antisense transcriptio

64 for "system bias" targeting of the IGF1R to uncouple downregulation from signaling.

65 at prevents overproliferation, mitochondrial uncoupling drugs also extend lifespan and inhibit intest

66 and 21st centuries, but fire extremes become uncoupled due to fire suppression after 1900.

67 we highlight P4HA2 as a potential target for uncoupling ECM signals that support cancer stemness.

68 findings reveal that IL-27 opposes IFN-I to uncouple effector differentiation from cell division and

69 Notably, proteinase K treatment uncoupled electron uptake from biofilm formation, likely

70 This uncoupling enables structural asymmetry of the overall h

71 rin B1 induced EphB1 phosphorylation and the uncoupling EphB1 from Cav-1 and thereby promoted phospho

72 To test this, we uncoupled ESX-5 from regulation by RegX3.

73 otein-1 (UCP1) in brown and beige adipocytes uncouples fatty acid oxidation from ATP generation in mi

74 ion fork progression, but the details of how uncoupled forks are restarted remain uncertain.

75 arterial vasodilatory response has begun to uncouple from the WSR stimulus.

76 Levels of (1) O(2) , however, could be uncoupled from chloroplast degradation, suggesting that

77 ata show that microvascular perfusion can be uncoupled from convective oxygen delivery, and that tiss

78 and the ligation of Okazaki fragments can be uncoupled from DNA replication and delayed until after s

79 the cell cycle at specific loci use pathways uncoupled from DNA synthesis.

80 ions in promoting telomere clustering can be uncoupled from enriching DNA repair factors.

81 hannel currents, reporting a catalytic cycle uncoupled from gating.

82 esults indicate that effector binding can be uncoupled from gene regulation.

83 table information that is sometimes entirely uncoupled from genetic variation.

84 main glucose transporter in ECs and becomes uncoupled from glycolysis during quiescence in a Notch-d

85 cr3 engineering facilitated Avr2 inhibition, uncoupled from HR signalling.

86 th high risk for glomerular toxicity that is uncoupled from hypertension, suggesting a direct link be

87 irulence factor-driven immunogenicity can be uncoupled from inflammatory pathogenicity.

88 icate that ARL13B's role within cilia can be uncoupled from its function outside of cilia.

89 ed double strand DNA breaks that is entirely uncoupled from its requisite engagement in DNA replicati

90 Thus, cardiac hypertrophy is uncoupled from profibrotic signaling in this mouse model

91 rmation in human cells and zebrafish that is uncoupled from replication.

92 the fast-spreading persistent isolate, were uncoupled from sustained viral loads, and were instead l

93 fork rates, despite lesion bypass occurring uncoupled from the Cdc45-MCM-GINS (CMG) helicase.

94 Metabolic adaptations in early pregnancy are uncoupled from the circadian clock, whereas in late preg

95 g: 1) MAIT cell activation and exhaustion is uncoupled from the hallmark depletion of MAIT cells duri

96 t genotype indicates that Pol IV can operate uncoupled from the high siRNA levels typically observed

97 Y-tongue conformation of IsPadC is partially uncoupled from the initial changes in the NTS.

98 ion of expression of inhibitory receptors is uncoupled from the loss of effector function.

99 We establish that motility can be uncoupled from the microtubule depolymerase activity and

100 plying that the lever arm rotation is mostly uncoupled from the motor domain.

101 ems show that divisions of stem cells can be uncoupled from their progeny differentiation, and the ou

102 In contrast, restored FP and HR could be uncoupled from therapy resistance when gaps were present

103 gly, Johnson et al. show that translation is uncoupled from transcription in Bacillus subtilis, argui

104 bservations indicate that AMPK regulation is uncoupled from V-ATPase activity in cancer cells and tha

105 At the elementary level (uncoupled from work output), redox catalysis by many enz

106 nected components of thalamus circuitry, but uncoupling from most other brain regions was observed-in

107 ows dramatically after bypass, likely due to uncoupling from the stalled leading strand.

108 This reaction uncouples GALC deficiency from psychosine accumulation,

109 We uncouple gene expression at the transcriptional, transla

110 resistant aggrecans with TIMP deficiency, we uncouple growth plate activity in axial and appendicular

111 enetic suppressor screens for mutations that uncouple growth-defense tradeoffs in the jazD mutant ide

112 ead RNA-editing changes and a strong genomes uncoupled (gun) molecular phenotype similar to gun1 MORF

113 structures in template, slowed helicase, or uncoupled helicase-polymerase, increase DNA reannealing

114 can be reconciled if the R(g) and R(ee) are "uncoupled" (i.e., no longer simply proportional), in con

115 Uncoupling IL-1beta/IL-1R1 signaling prevents disease, p

116 gn uniformly across the brain, but gradually uncouple in higher-order polysensory areas.

117 rating that scarring and regeneration can be uncoupled in adult biliary disease and regeneration.

118 hypoxia and HIF-1alpha stabilization can be uncoupled in cancer.

119 ve ductal carcinoma in situ lesions but were uncoupled in triple-negative breast cancer (TNBC), a sub

120 uscle and increased markers of mitochondrial uncoupling in BAT suggest that BD-AcAc(2) initiates a tr

121 Finally, caveolae disruption promotes eNOS uncoupling in normotensive and hypertensive rat vessels

122 multiple instances of cellular and molecular uncoupling in Prdm9(-/-) mutants.

123 The absence of mitochondrial uncoupling in skeletal muscle and increased markers of m

124 sion of per mutants depends on mitochondrial uncoupling in the intestine.

125 orting the detrimental role of mitochondrial uncoupling in the pathogenesis of WMI.

126 ated model, we correlated the extent of this uncoupling in TNBC cell lines with the importance of NRF

127 h processes involved in cell turnover become uncoupled, including pharmacological treatments and dise

128 hrin coat formation and cargo sorting can be uncoupled, indicating that a checkpoint is required for

129 the Toll-IL-1R protein SARM from macrophages uncouples inflammasome-dependent cytokine release and py

130 it breaks faster than its noninterlocked or uncoupled interlocked (i.e., pulled from both sides of t

131 oes not follow physiological dynamics due to uncoupled intrinsic and synaptic maturation.

132 TFAM-induced mild uncoupling is shown to protect mitochondrial membrane po

133 BAI1 loss lowers RhoA activation and uncouples it from dendrite dynamics, causing overgrowth.

134 nsient nature and the difficulty involved in uncoupling it from genetic variation, it is unclear whet

135 f cellular energy-conserving mechanisms, and uncouples its binding with ciliary kinesin Kif19a.

136 on of TOP2cc was suppressed, the TOP2 enzyme uncoupled itself from the DNA following ETO washout, in

137 Intriguingly, we find that ovariectomy uncouples lifespan from metabolic health, with ovariecto

138 ally associated with increased lysosomal pH, uncoupling lysosomal function from cell proliferation.

139 Uncoupling may lead to the arrest of transcription throu

140 ly promoting the decrease in cyclin/Cdk1, we uncoupled MBT from N/C increase, arguing that N/C-guided

141 e-negative results driven by a neurovascular uncoupling mechanism.

142 More importantly, tau knockdown uncouples microtubule destabilization from glucose stimu

143 In vitro, beige adipocytes exhibit uncoupled mitochondrial respiration and cAMP-induced lip

144 in D-dependent mitochondrial proton leak and uncoupled mitochondrial respiration, leading to transien

145 Coupled or uncoupled mitochondrial respiratory rates in skeletal mu

146 or superfamily domain containing 7C (MFSD7C) uncouples mitochondrial respiration to switch ATP synthe

147 s enabling strong coupling between otherwise uncoupled modes.

148 ar assembly categorized as spectroscopically uncoupled molecules.

149 nsin loop extrusion occurs by 2 independent, uncoupled motor activities; the motors translocate on DN

150 Hyperglycemia further exacerbates this uncoupled mutualism.

151 l inhibition of TEAD and Lats suppresses Wnt-uncoupled Myc upregulation and epithelial over-prolifera

152 ed endothelium-dependent vasodilation due to uncoupled NO synthase (NOS).

153 roles of Fgfr1 and Fgfr2 in development and uncouple novel FGFR kinase-dependent cell adhesion prope

154 vides a mechanistically informed approach to uncouple obesity and breast cancer in a rapidly growing

155 s for designing antiheparanase approaches to uncouple obesity and breast cancer in a rapidly growing

156 adipogenesis may lead to novel strategies to uncouple obesity from metabolic disease.

157 PGA manifests as an uncoupling of airway obstruction from airway inflammatio

158 nce for multiple unusual features, including uncoupling of carotenoid and phytol metabolism, a limite

159 l populations show a previously unrecognized uncoupling of CD4 T cell help that is otherwise required

160 Together with previous reports that suggest uncoupling of CD69 expression and tissue residency, thes

161 utant desmin assembly complexes underlie the uncoupling of desmin filaments from intercalated discs a

162 mediated by activation of the NADPH oxidase, uncoupling of endothelial and neuronal nitric oxide synt

163 We conclude that NOX5-induced uncoupling of endothelial NOS is a causal mechanism and

164 function of caveolin 1 (CAV1) and subsequent uncoupling of feedback mechanisms between CAV1, the matr

165 This uncoupling of general availability of mRNA from translat

166 IR of female PGCs caused uncoupling of germ cell differentiation and meiotic init

167 Interestingly, uncoupling of GOLPH3 from its binding partner MYO18A res

168 Consequently, opto-/chemogenetic uncoupling of hierarchical information flow disrupted af

169 HFS throughout the light-dark cycle suggests uncoupling of hypothalamic responses involving appetite-

170 By mutational analysis and uncoupling of ISW1a's dinucleosome specificity, we find

171 ionally promotes the physical and functional uncoupling of LDs from mitochondria, reducing fatty acid

172 ls suppresses secretion, leading to a unique uncoupling of normal female postmating responses to the

173 several systems, most notably the regulated uncoupling of oxidative phosphorylation from ATP generat

174 ate testable predictions for coupling versus uncoupling of phenotypic evolution of tadpole and adult

175 ytoplasmic aggregates and a complete spatial uncoupling of phospho-myosin from F-actin.

176 ted by depletion of Kin28, thus revealing an uncoupling of Taf and TBP occupancy during the transcrip

177 low spatial resolution or electromechanical uncoupling of the beating heart.

178 tranded regions formed because of stochastic uncoupling of the leading-strand DNA polymerase from the

179 to ATP or the antagonist suramin, suggesting uncoupling of the pore and the ligand binding domains.

180 ) high P(i)-sensitivity and selectivity, (2) uncoupling of the read-out signal from potential chemica

181 ning the molecular mechanisms regulating the uncoupling of the reproduction-maintenance trade-off in

182 However, as queens possess an atypical uncoupling of the reproduction-maintenance trade-off typ

183 racilis We show that, rather than comparable uncoupling of the two pathways, the trnE mutation is let

184 insights into brain angiogenesis by showing uncoupling of vessel morphogenesis and blood-brain barri

185 in older people, and there appears to be an 'uncoupling' of WSR from FMD in older people that may ref

186 enched by 11-cis-retinal, and was blocked by uncoupling opsin from phototransduction, all indicating

187 scle mitochondrial respiratory function, and uncouple oxygen consumption from ATP production.

188 imary endothelial cells results in decreased uncoupled oxygen consumption, increased fission, decreas

189 hondrial biogenesis as measured by increased uncoupled oxygen consumption, mitochondrial DNA content,

190 xchange, as revealed by combination with the uncoupling p.Glu200Ala substitution.

191 led pathway, as well as an overlooked proton-uncoupled pathway that does not involve proton transfer.

192 ng in intestinal stem cell depletion and Wnt-uncoupled progenitor expansion.

193 enomenon was complicated by our inability to uncouple protein binding from DNA condensation.

194 lastid trnE gene, which has been reported to uncouple protein biosynthesis from tetrapyrrole biosynth

195 ngineered a synthetic isoform of PNPLA3 that uncouples protein accumulation from loss of enzymatic ac

196 cle mitochondrial function and expression of uncoupling protein (UCP) 3, ADP/ATP carrier protein (AAC

197 expression of the brown fat signature genes uncoupling protein (UCP)-1 and peroxisome proliferator-a

198 the expression of sirtuin-1 and thermogenic uncoupling protein 1 (UCP-1) in the iWAT.

199 expression of PPARalpha target genes such as uncoupling protein 1 (Ucp1) and adrenoreceptor beta 3 (A

200 MDMA treated animals showed increased uncoupling protein 1 (UCP1) and TGR5 expression levels i

201 ervating BAT, and dramatically increased BAT uncoupling protein 1 (Ucp1) expression and activity in a

202 hese findings, smokers show higher levels of uncoupling protein 1 (UCP1) expression in WAT, which cor

203 elective mast cell deletion of Tph1 enhances uncoupling protein 1 (Ucp1) expression in white adipose

204 expenditure (EE) and decreased expression of uncoupling protein 1 (UCP1) in brown adipose tissue.

205 We observed expression of uncoupling protein 1 (UCP1) in SAT exposed to PDAC exoso

206 Uncoupling protein 1 (UCP1) plays a central role in nons

207 also dissipate this proton gradient through uncoupling protein 1 (UCP1) to generate heat, but the ev

208 consistently led to the ectopic formation of uncoupling protein 1 (UCP1)(+pos) adipose tissue with lo

209 s capacity for cell-autonomous expression of uncoupling protein 1 (UCP1), a biomarker of beige and br

210 of brown adipose thermogenic markers such as uncoupling protein 1 (UCP1), PR domain containing 16, an

211 ering thermogenesis is mediated primarily by uncoupling protein 1 (UCP1), the development of the UCP1

212 ogram and fatty acid oxidation, 2) stimulate uncoupling protein 1 (UCP1)-independent respiration in s

213 ein DeltaPsi is intrinsically low because of uncoupling protein 1 (UCP1).

214 steine-replacing cysteine at position 253 in uncoupling protein 1 (UCP1).

215 lipids, through activation of mitochondrial uncoupling protein 1 (UCP1).

216 ducible beige adipocytes as the emergence of uncoupling protein 1 after cold exposure was restricted

217 resembles the H(+) leak via the thermogenic uncoupling protein 1 found in brown fat.

218 ative phosphorylation from ATP generation by uncoupling protein 1, a tissue-specific protein present

219 Mechanistically, ROS promoted uncoupling protein 2 (UCP2) protein expression and phosp

220 The mitochondrial uncoupling protein 2 (UCP2) relieves oxidative and neuro

221 Uncoupling protein 2 (UCP2), a mitochondrial anion carri

222 MAF BZIP transcription factor A (MafA), and uncoupling protein 2 (Ucp2).

223 f proton transport mediated by mitochondrial uncoupling protein 2 (UCP2).

224 tor gamma co-activator alpha (Pgc1alpha) and uncoupling protein 2 expression, suggesting mechanisms f

225 mics signature in mice overexpressing muscle uncoupling protein 3.

226 This novel protective consequence of uncoupling protein inhibition may lead to new therapeuti

227 Moreover, upregulated uncoupling protein UCP4C in intestinal stem cells and en

228 In mammals, uncoupling protein-1 (UCP1) in brown and beige adipocyte

229 Uncoupling protein-1 (UCP1) plays a central role in ener

230 ulation of thermogenic adipocytes expressing uncoupling protein-1 (Ucp1) regulates energy dissipation

231 Both CL and Tregs induced much higher UCP-1 (uncoupling protein-1) expression in SAT from females tha

232 mitochondrial uncoupling and thermogenesis (uncoupling protein-1, deiodinase-2, and peroxisome proli

233 ion of brownlike adipocytes expressing UCP1 (uncoupling-protein-1) in subcutaneous white adipose tiss

234 regulators of mitochondrial function are the uncoupling proteins, particularly UCP2.

235 thase as well as by neonatal upregulation of uncoupling proteins.

236 Hence, GCBCs appear to uncouple rapid proliferation from aerobic glycolysis.

237 ency to propagate than spindles occurring in uncoupled regions.

238 Day 1-2 maximal uncoupled respiration (9.7 +/- 7.7 vs 13.7 +/- 4.1 pmol

239 ed in the priming of mitochondria to perform uncoupled respiration downstream of adenylate cyclase.

240 No evidence for uncoupled respiration or "browning" of the white adipose

241 se tissue (WAT) promotes oxygen consumption, uncoupled respiration, and heat production during cold-

242 ed BAs undergo elevated rates of glycolysis, uncoupled respiration, and lipolysis that are responsive

243 highlight a role for AKAP1 in thermogenesis, uncoupled respiration, and regulation energy balance.

244 d mitochondrial Ca(2+) overload and impaired uncoupled respiration.

245 a as well as attenuated forskolin-stimulated uncoupled respiration.

246 Uncoupling respiration from ATP synthesis or increasing

247 lf-life further is ultimately dependent upon uncoupling rFVIII from endogenous VWF.

248 thalamic activity suppression during spindle-uncoupled ripples is favorable for memory replay, as it

249 mic activity suppression at times of spindle-uncoupled ripples may be favorable for memory replay, as

250 eep, MD firing rate decreased around spindle-uncoupled ripples, but increased around spindle-coupled

251 In particular, uncoupled RNAPs in B. subtilis explain the diminished ro

252 4Fe-4S] cluster, catalyzes an enhancement of uncoupled S-adenosylmethionine cleavage relative to WT,

253 es the first proposed systemic mechanism for uncoupled SCN cell division and differentiation.

254 we observed that when their mitochondria are uncoupled, SDH-deficient cells are unable to preserve th

255 ized (3Cs) CRISPR/Cas gRNA reagents and that uncouples sequence diversity from sequence distribution.

256 ) approaches will enable scientists to study uncoupled spatiotemporal regulation of different genetic

257 otochemical, and electrochemical methods for uncoupling substrate reduction from ATP hydrolysis, whic

258 neurodegenerative disorders, suggesting that uncoupling synaptic activity from nuclear signaling may

259 gs demonstrate that ATG5-dependent autophagy uncouples T-cell proliferation from its effector functio

260 rpine1, also known as PAI-1), due in part to uncoupled TGF-beta-mediated suppression of miR-30c.

261 e most cell types, MEFs have the capacity to uncouple the glycolytic utilization of glucose from mito

262 ability of the phyB mutations to completely uncouple the mild growth-defense phenotypes in a jaz mut

263 rane dimers oligomerize into small holes and uncouple the proton gradient.

264 bilayer unzipping technique was designed to uncouple the two leaflets of the SLB.

265 temperatures and higher soil moisture, which uncoupled the negative effects of heating on cellular- a

266 paths prior to alignment, which effectively uncouples the iterative access of the assembly graph and

267 e utilized BAM15, a potent protonophore that uncouples the mitochondria without depolarizing the plas

268 Importantly, abatacept uncouples the relationship between changes in T cell sub

269 the interleukin-1 (IL-1) pathway completely uncouples the SASP from other senescence-associated phen

270 This cleavage uncouples the stress-sensing and signaling domains of IR

271 localized to distinct cellular compartments, uncoupling the nuclear and mitochondrial functions of FO

272 l spectrins in peripheral sensory neurons to uncouple their nodal functions from their axon initial s

273 effector cytokines and cytotoxic functions, uncoupling their proliferation and effector functions.

274 put synapses of SOM-INs and can functionally uncouple them from local network with implications for r

275 ), to determine the effects of mitochondrial uncoupling therapy on T2D, and the pathogenesis of DPN,

276 k, AAC connects coupled (ATP production) and uncoupled (thermogenesis) energy conversion in mitochond

277 pt a cyclin-dependent kinase (CDK) sensor to uncouple these key events of the cell cycle in Caenorhab

278 demethylation pathways, the lack of tools to uncouple these sequential oxidative events has constrain

279 Our study selectively uncouples these distinct regulatory mechanisms within NS

280 lowing ATP hydrolysis, demonstrating that it uncouples these two steps.

281 Uncoupling these processes through genome duplications l

282 ion genes, and constructed an in vivo system uncoupling these regulatory genes to show that RappLS20

283 se T helper 1 (T(H)1) cells by biochemically uncoupling these two processes.

284 Loss or knockdown of delta-catenin uncoupled this coordination, leading to retraction of th

285 e cytosolic Fe-S biogenesis system, and that uncoupling this process triggers leaf-associated Fe-S- a

286 Increased NGR5 activity consequently uncouples tillering from nitrogen regulation, boosting r

287 tabolic systems was dynamic and shifted from uncoupled to coupled under metabolic stress.

288 d by endogenous sRNAs has an important role, uncoupled to defense, in the production of symptoms asso

289 e receipt of financial penalties - even when uncoupled to performance - can prevent irrelevant inform

290 t this helps balance the need for sufficient uncoupling to activate the DNA replication checkpoint wi

291 for enhancer control of Sox2 expression that uncouples transcription from enhancer proximity.

292 By uncoupling translation from mRNA localization, we untang

293 T(1)T(1)) state and the processes leading to uncoupled triplets (T(1)) were studied at room temperatu

294 T) pathways, which may be protective against uncoupled turnover or provide an ET pathway to the activ

295 protein active site from inactivation during uncoupled turnover.

296 tion and cell migration that were rescued by uncoupling VE-cadDEE from actin.

297 ADH recycling, associated with mitochondrial uncoupling, were not compensated by increased lactic fer

298 e effects, where both heart and RM increased uncoupling whether the assay temperature was acutely cha

299 ed in fatty acid oxidation and mitochondrial uncoupling, which are necessary for development of funct

300 demonstrate that pharmacologic mitochondrial uncoupling with BAM15 has powerful anti-obesity and insu