ライフサイエンスコーパス: uncoupling

1 ve rat and SHR vessels, which suggested eNOS uncoupling.

2 ncoupling protein 3 (UCP3) and mitochondrial uncoupling.

3 educed antioxidant capacity of cells and NOS uncoupling.

4 blasts during pharmacological gap junctional uncoupling.

5 l membrane potential following mitochondrial uncoupling.

6 of the carrier to adrenergic activation and uncoupling.

7 fatty acid and glucose oxidation, as well as uncoupling.

8 NAFLD is via salicylate-driven mitochondrial uncoupling.

9 is by dissipating energy through thermogenic uncoupling.

10 ular respiration via increased mitochondrial uncoupling.

11 e apoptosis during adrenergic stimulation of uncoupling.

12 ecreases caloric efficiency by mitochondrial uncoupling.

13 ance to halothane- and acidification-induced uncoupling, absence of voltage-dependent fast inactivati

14 consumption rate as an assay for determining uncoupling activity, changes on the 5- and 6-position of

15 ss the mitochondrial inner membrane, thereby uncoupling adenosine diphosphate phosphorylation from nu

16 that globally targeting mitochondria with an uncoupling agent is unlikely to provide therapeutic bene

17 e stimulation by introducing a mitochondrial uncoupling agent to the microchannel, enabling determina

18 development of liver-targeted mitochondrial uncoupling agents as a potential novel therapy for lipod

19 mapping in the absence of electromechanical uncoupling agents, the method relieves a long-standing l

20 is results in ventricular-pulmonary vascular uncoupling and acute RV dilation.

21 H4, which resulted in nitric oxide synthases uncoupling and augmented radiation-induced ROS.

22 RATIONALE: Intercellular uncoupling and Ca(2+) (Ca) mishandling can initiate trig

23 late unwinding following helicase-polymerase uncoupling and establishment of prolonged stalled fork s

24 mplate aberrations cause helicase-polymerase uncoupling and impede replication fork progression, but

25 o limit the reduction in stroke volume, with uncoupling and increased wall stress as a consequence.

26 se, Pol delta, binds the leading strand upon uncoupling and inhibits TLS.

27 s deregulation can explain the mitochondrial uncoupling and lower ATP levels in VCP mutation-bearing

28 d other proteins indicative of mitochondrial uncoupling and nonshivering adaptive thermogenesis.

29 Respiratory uncoupling and ROS excess occurred at PCoA > 600 nmol/mg

30 clusively by combined application of contact uncoupling and TGFbeta.

31 However, the extent of this uncoupling and the roles of DNA methylation in shaping d

32 t among groups, but markers of mitochondrial uncoupling and thermogenesis (uncoupling protein-1, deio

33 in perfusate temperature, electromechanical uncoupling, and acute ischemia/reperfusion injury.

34 reased tPA activity, prevented neurovascular uncoupling, and ameliorated cognition in 11- to 12-month

35 metabolic substrate usage and mitochondrial uncoupling, and protects against ischaemia/reperfusion.

36 tional anti-CTLA4 DVD provides an avenue for uncoupling antitumor efficacy from immunotherapy-induced

37 on in apoptotic cells and inhibits CPS, thus uncoupling apoptosis from CPS.

38 ative stress and nitric oxide synthase (NOS) uncoupling are thought to contribute to Fabry cardiovasc

39 state connectivity, to explore neurovascular uncoupling as a mechanism underlying these changes, and

40 in D-dependent mitochondrial proton leak and uncoupling as a potentially novel subcellular mechanism

41 but decreased ATP, suggesting mitochondrial uncoupling as its mechanism of action.

42 ile lipid cycling, rather than mitochondrial uncoupling, as a way to increase energy expenditure in C

43 (HUVECs) treated with dextrin confirmed eNOS uncoupling, as verified by the reduced eNOS dimer/monome

44 regulator of macroautophagy during mitosis, uncoupling autophagy regulation from nutrient status to

45 This temporal uncoupling became larger in short photoperiods and may r

46 This uncoupling between association and causation may result

47 ine-bound closed conformation, revealing the uncoupling between ATP-PRT open and closed conformations

48 Thus, uncoupling between two fundamental physiological paramet

49 plies a selection for aerobic glycolysis and uncoupling biosynthesis from NADH generation.

50 an imbalance in glucose carbon allocation by uncoupling biosynthetic pathway activity, which could di

51 ore bone density, structure, and strength by uncoupling bone formation from resorption.

52 Due to uncoupling, brown adipose tissue (BAT) dissipates energy

53 een proposed that AAC mediates mitochondrial uncoupling, but it has proven difficult to demonstrate t

54 Neurovascular uncoupling by cocaine during stimulation but not during

55 V or caCaMKIV, respectively, suggesting that uncoupling CaMKIV activation from activity generates an

56 nteracts with cellulose synthase-microtubule uncoupling (CMU) proteins that are important for the mic

57 circadian-regulated intestinal mitochondrial uncoupling controls longevity in Drosophila and suggest

58 uggests that the H(+) leak and mitochondrial uncoupling could be dynamically controlled by cellular A

59 Neurovascular uncoupling could contribute to cocaine's neurotoxicity,

60 t produces mild liver-targeted mitochondrial uncoupling could decrease hypertriglyceridemia and rever

61 are differentially regulated in response to uncoupling Crkl from its signaling pathways in the devel

62 at S384 by the PP2A-B56 phosphatase, thereby uncoupling cyclin E degradation from cyclin E-CDK2 activ

63 e consequential complexities associated with uncoupling defence responses.

64 xpected for a process in which mitochondrial uncoupling diminishes ATP production, a mitochondrial pr

65 Uncoupling discovery from genotyping thus allows for the

66 Uncoupling DNA demethylation from antisense transcriptio

67 at prevents overproliferation, mitochondrial uncoupling drugs also extend lifespan and inhibit intest

68 we highlight P4HA2 as a potential target for uncoupling ECM signals that support cancer stemness.

69 This uncoupling effect is tightly correlated with the suppres

70 oA oxidation and its concentration-dependent uncoupling effect, together with a partial lipid-depende

71 ed by NTZ in real time by virtue of its mild uncoupling effect.

72 e fuel role of lipids is influenced by their uncoupling effects, and how this affects mitochondrial e

73 n adipose tissue, where it generates heat by uncoupling electron transport from ATP production.

74 This uncoupling enables structural asymmetry of the overall h

75 rin B1 induced EphB1 phosphorylation and the uncoupling EphB1 from Cav-1 and thereby promoted phospho

76 adation, but increases chromosomal breakage, uncoupling fork protection, and chromosome stability.

77 nected components of thalamus circuitry, but uncoupling from most other brain regions was observed-in

78 ed cellulose synthesis enabled by regulatory uncoupling from primary wall synthesis.

79 s lacking these residues results in complete uncoupling from the cell cycle.

80 yofilament Ca(2+) sensitivity and, moreover, uncoupling from the impact of phosphorylation of cTnI me

81 ows dramatically after bypass, likely due to uncoupling from the stalled leading strand.

82 Uncoupling IL-1beta/IL-1R1 signaling prevents disease, p

83 uscle and increased markers of mitochondrial uncoupling in BAT suggest that BD-AcAc(2) initiates a tr

84 Finally, caveolae disruption promotes eNOS uncoupling in normotensive and hypertensive rat vessels

85 multiple instances of cellular and molecular uncoupling in Prdm9(-/-) mutants.

86 The absence of mitochondrial uncoupling in skeletal muscle and increased markers of m

87 Our results validate a prevalence of uncoupling in the evolution of tadpole and adult phenoty

88 sion of per mutants depends on mitochondrial uncoupling in the intestine.

89 orting the detrimental role of mitochondrial uncoupling in the pathogenesis of WMI.

90 ated model, we correlated the extent of this uncoupling in TNBC cell lines with the importance of NRF

91 Uncoupling innate and adaptive functions of cDCs reveale

92 TFAM-induced mild uncoupling is shown to protect mitochondrial membrane po

93 by endothelial nitric oxide synthase (eNOS) uncoupling, is an initial step in atherosclerosis.

94 nsient nature and the difficulty involved in uncoupling it from genetic variation, it is unclear whet

95 ing the remodelling and turnover of K16, and uncoupling it from K6, iRHOM2 regulates the epithelial r

96 -p38 MAPK-CMA pathway in the mouse brain and uncoupling it results in a greater loss of SNc dopaminer

97 Finally, the uncoupling led to an accumulation of apoptotic newborn c

98 ally associated with increased lysosomal pH, uncoupling lysosomal function from cell proliferation.

99 adipogenic, insulin sensitivity, and energy uncoupling machinery, while limiting inflammation in WAT

100 Uncoupling may lead to the arrest of transcription throu

101 hetic anion transporters and potentially the uncoupling mechanism of naturally occurring membrane pro

102 e-negative results driven by a neurovascular uncoupling mechanism.

103 By uncoupling membrane binding from internalization, we fou

104 Blocking ROS production with rotenone by uncoupling mitochondria or by expressing the alternative

105 y transition pores (mPTP) causes respiratory uncoupling, mitochondrial injury, and cell death.

106 Thus, NBP is a conserved uncoupling motif of the ecto-TM domain transition and th

107 wever, regulated their mRNA concentration by uncoupling mRNA stability from the transcription rate.

108 We also conclude that, by uncoupling mRNA synthesis from decay, cells control the

109 Uncoupling MTFP1 levels from the mTORC1/4E-BP pathway up

110 hondrial matrix independent of ATP synthase, uncoupling nutrient metabolism from ATP generation.

111 ies used in this study but also displayed an uncoupling of A and gs in most of the species.

112 therapeutic efficacy through pharmacological uncoupling of a convergence point of NF-kappaB-mediated

113 PGA manifests as an uncoupling of airway obstruction from airway inflammatio

114 associated with enhanced downregulation and uncoupling of beta2-receptors.

115 The uncoupling of C fixation from dissolved inorganic nitrog

116 halamic inflammatory pathways results in the uncoupling of caloric intake and energy expenditure, fos

117 nce for multiple unusual features, including uncoupling of carotenoid and phytol metabolism, a limite

118 l populations show a previously unrecognized uncoupling of CD4 T cell help that is otherwise required

119 Together with previous reports that suggest uncoupling of CD69 expression and tissue residency, thes

120 Our results indicate an uncoupling of cellular, tissue, and organismal aging thr

121 The uncoupling of complex II's electron transport function f

122 utant desmin assembly complexes underlie the uncoupling of desmin filaments from intercalated discs a

123 has no effect on work output, indicating an uncoupling of disassembly speed from protofilament strai

124 mediated by activation of the NADPH oxidase, uncoupling of endothelial and neuronal nitric oxide synt

125 We conclude that NOX5-induced uncoupling of endothelial NOS is a causal mechanism and

126 function of caveolin 1 (CAV1) and subsequent uncoupling of feedback mechanisms between CAV1, the matr

127 The mutagenic uncoupling of femtosecond motions between catalytic site

128 This uncoupling of general availability of mRNA from translat

129 IR of female PGCs caused uncoupling of germ cell differentiation and meiotic init

130 Interestingly, uncoupling of GOLPH3 from its binding partner MYO18A res

131 A at supersaturating concentrations to cause uncoupling of H1 receptors from phospholipase C.

132 Consequently, opto-/chemogenetic uncoupling of hierarchical information flow disrupted af

133 HFS throughout the light-dark cycle suggests uncoupling of hypothalamic responses involving appetite-

134 tro via tyrosine phosphatase SHP-1-dependent uncoupling of IL-2Rbeta signaling.

135 act epithelia; the other prerequisite is the uncoupling of intercellular contacts, which induces Rho-

136 By mutational analysis and uncoupling of ISW1a's dinucleosome specificity, we find

137 ionally promotes the physical and functional uncoupling of LDs from mitochondria, reducing fatty acid

138 dent impaired autophagic flux after chemical uncoupling of mitochondria, increased mitochondrial-prot

139 We propose that the uncoupling of neurogenesis and differentiation could pro

140 Reduced bioavailability or uncoupling of nitric oxide in the kidney, leading to dec

141 Inadequate availability of BH4 leads to uncoupling of nitric oxide synthases and production of h

142 ls suppresses secretion, leading to a unique uncoupling of normal female postmating responses to the

143 several systems, most notably the regulated uncoupling of oxidative phosphorylation from ATP generat

144 a highly phase-specific pattern, suggesting uncoupling of phenotypic evolution across life-history p

145 ate testable predictions for coupling versus uncoupling of phenotypic evolution of tadpole and adult

146 ytoplasmic aggregates and a complete spatial uncoupling of phospho-myosin from F-actin.

147 Here, we show that uncoupling of polymerized TUBB3 with netrin-1-repulsive

148 NPQ recovery in the dark requires uncoupling of PsbS.

149 The uncoupling of safety from other xylem functions allowed

150 ute PI3K activation and provide evidence for uncoupling of Ser(473) and Thr(308) phosphorylation, as

151 Our results demonstrate uncoupling of symbiosis and the symbiotic root developme

152 ted by depletion of Kin28, thus revealing an uncoupling of Taf and TBP occupancy during the transcrip

153 tion of GC responses was, in part, caused by uncoupling of Tfh-B cell interactions, as evidenced by r

154 low spatial resolution or electromechanical uncoupling of the beating heart.

155 These findings indicate an uncoupling of the canonical Akt/FoxO1 pathway in HCV pro

156 The similarities include regulatory uncoupling of the CESAs that synthesize primary and seco

157 n, pharmacologically induced neuromechanical uncoupling of the diaphragm should facilitate lung-prote

158 tranded regions formed because of stochastic uncoupling of the leading-strand DNA polymerase from the

159 hat has little constitutive activity reveals uncoupling of the ligand-binding domain from conserved c

160 ia TSC1 gene deletion in chondrocytes causes uncoupling of the normal proliferation and differentiati

161 to ATP or the antagonist suramin, suggesting uncoupling of the pore and the ligand binding domains.

162 ) high P(i)-sensitivity and selectivity, (2) uncoupling of the read-out signal from potential chemica

163 in avian DT40 cells, indicative of extensive uncoupling of the replicative helicase and polymerase.

164 ning the molecular mechanisms regulating the uncoupling of the reproduction-maintenance trade-off in

165 However, as queens possess an atypical uncoupling of the reproduction-maintenance trade-off typ

166 racilis We show that, rather than comparable uncoupling of the two pathways, the trnE mutation is let

167 ural features within the S4-S5 linker permit uncoupling of the voltage sensor from the pore in the ab

168 sor-competent and -incompetent molecules and uncoupling of the VSR and particle assembly capacities.

169 The uncoupling of tissue growth and neurogenesis is shown to

170 The mechanism of iRAPs involves active uncoupling of transcription and translation, making nasc

171 insights into brain angiogenesis by showing uncoupling of vessel morphogenesis and blood-brain barri

172 Structure-guided mutagenesis enabled uncoupling of virulence from I-2-mediated recognition.

173 in older people, and there appears to be an 'uncoupling' of WSR from FMD in older people that may ref

174 enched by 11-cis-retinal, and was blocked by uncoupling opsin from phototransduction, all indicating

175 xchange, as revealed by combination with the uncoupling p.Glu200Ala substitution.

176 e and inhibited by IL-4R-signaling in vitro, uncoupling parasite killing from expulsion mechanisms.

177 The mitochondrial carrier uncoupling protein (UCP) 2 belongs to the family of the

178 cle mitochondrial function and expression of uncoupling protein (UCP) 3, ADP/ATP carrier protein (AAC

179 pathetic stimulation, activate mitochondrial uncoupling protein (UCP)-1 and oxidize fatty acids to ge

180 expression of the brown fat signature genes uncoupling protein (UCP)-1 and peroxisome proliferator-a

181 on of caloric excess through the activity of uncoupling protein (UCP)-1.

182 the expression of sirtuin-1 and thermogenic uncoupling protein 1 (UCP-1) in the iWAT.

183 In uncoupling protein 1 (UCP-1) knockout mice, the middle a

184 wn AT showed reduced activity with decreased uncoupling protein 1 (ucp-1), cell death-inducing DFFA-l

185 expression of PPARalpha target genes such as uncoupling protein 1 (Ucp1) and adrenoreceptor beta 3 (A

186 dipocytes are specialized cells that express uncoupling protein 1 (UCP1) and dissipate chemical energ

187 m promoters of BAT-specific genes, including uncoupling protein 1 (Ucp1) and peroxisome proliferator-

188 MDMA treated animals showed increased uncoupling protein 1 (UCP1) and TGR5 expression levels i

189 Both uncoupling protein 1 (UCP1) and UCP3 are important for m

190 h was accompanied by increased expression of uncoupling protein 1 (UCP1) and UCP3 in brown adipose ti

191 ervating BAT, and dramatically increased BAT uncoupling protein 1 (Ucp1) expression and activity in a

192 hese findings, smokers show higher levels of uncoupling protein 1 (UCP1) expression in WAT, which cor

193 elective mast cell deletion of Tph1 enhances uncoupling protein 1 (Ucp1) expression in white adipose

194 nduces mitochondrial dysfunction and reduces uncoupling protein 1 (UCP1) expression.

195 t production and decreased the expression of uncoupling protein 1 (UCP1) in brown adipose tissue (BAT

196 expenditure (EE) and decreased expression of uncoupling protein 1 (UCP1) in brown adipose tissue.

197 is is primarily accomplished by induction of uncoupling protein 1 (UCP1) in brown and beige adipocyte

198 We observed expression of uncoupling protein 1 (UCP1) in SAT exposed to PDAC exoso

199 Uncoupling protein 1 (UCP1) is highly expressed in brown

200 Uncoupling protein 1 (UCP1) is nearly absent in brown ad

201 Uncoupling protein 1 (UCP1) is the established mediator

202 Uncoupling protein 1 (UCP1) plays a central role in nons

203 also dissipate this proton gradient through uncoupling protein 1 (UCP1) to generate heat, but the ev

204 consistently led to the ectopic formation of uncoupling protein 1 (UCP1)(+pos) adipose tissue with lo

205 s capacity for cell-autonomous expression of uncoupling protein 1 (UCP1), a biomarker of beige and br

206 al analysis revealed extensive expression of uncoupling protein 1 (UCP1), a definitive marker of brow

207 t of glucose homeostasis were independent of uncoupling protein 1 (UCP1), but required expression of

208 protein restriction increases adipose tissue uncoupling protein 1 (UCP1), energy expenditure and food

209 uce expression of thermogenic genes, such as uncoupling protein 1 (Ucp1), in adipocytes cultured with

210 of brown adipose thermogenic markers such as uncoupling protein 1 (UCP1), PR domain containing 16, an

211 ering thermogenesis is mediated primarily by uncoupling protein 1 (UCP1), the development of the UCP1

212 Both brown adipose tissue (BAT) (i.e. uncoupling protein 1 (UCP1)-based) and skeletal muscle (

213 ogram and fatty acid oxidation, 2) stimulate uncoupling protein 1 (UCP1)-independent respiration in s

214 lipids, through activation of mitochondrial uncoupling protein 1 (UCP1).

215 steine-replacing cysteine at position 253 in uncoupling protein 1 (UCP1).

216 thermogenesis, which requires mitochondrial uncoupling protein 1 (UCP1).

217 both electron transport chain components and uncoupling protein 1 (UCP1).

218 on the principal effector of thermogenesis: uncoupling protein 1 (UCP1).

219 ough thermogenic respiration, which requires uncoupling protein 1 (UCP1).

220 ein DeltaPsi is intrinsically low because of uncoupling protein 1 (UCP1).

221 ducible beige adipocytes as the emergence of uncoupling protein 1 after cold exposure was restricted

222 temperature as a result of higher levels of uncoupling protein 1 and a low abundance of the proinfla

223 loss was significantly associated with less uncoupling protein 1 expression (P = 0.006, R(2) = 0.09)

224 Pep19 induced uncoupling protein 1 expression in both white adipose ti

225 Uncoupling protein 1 expression induced by Pep19 in 3T3-

226 resembles the H(+) leak via the thermogenic uncoupling protein 1 found in brown fat.

227 Uncoupling protein 1(+) beige adipocytes are dynamically

228 neither presence nor thermogenic function of uncoupling protein 1(+) beige adipocytes contributed to

229 ative phosphorylation from ATP generation by uncoupling protein 1, a tissue-specific protein present

230 ramembraneous segments and the mitochondrial uncoupling protein 1, which is a transmembrane protein e

231 d body weight gain, induced the formation of uncoupling protein 1-positive beige adipocytes in white

232 wn adipose tissue respiration independent of uncoupling protein 1.

233 Additionally, intracellular glutathione and uncoupling protein 2 (UCP2) gene expressions were quanti

234 Mechanistically, ROS promoted uncoupling protein 2 (UCP2) protein expression and phosp

235 The mitochondrial uncoupling protein 2 (UCP2) relieves oxidative and neuro

236 Uncoupling protein 2 (UCP2), a mitochondrial anion carri

237 MAF BZIP transcription factor A (MafA), and uncoupling protein 2 (Ucp2).

238 f proton transport mediated by mitochondrial uncoupling protein 2 (UCP2).

239 ty from inflammation via upregulation of the uncoupling protein 2 (UCP2).

240 elated peptide 1 (DRP1) under the control of uncoupling protein 2 (UCP2).

241 tor gamma co-activator alpha (Pgc1alpha) and uncoupling protein 2 expression, suggesting mechanisms f

242 They also exhibit decreased uncoupling protein 3 (UCP3) and mitochondrial uncoupling

243 Uncoupling protein 3 (UCP3) is highly selectively expres

244 ion, fatty acid oxidation, and mitochondrial uncoupling protein 3 (UCP3) levels, while increasing gly

245 mics signature in mice overexpressing muscle uncoupling protein 3.

246 This novel protective consequence of uncoupling protein inhibition may lead to new therapeuti

247 the well-known betaAR-dependent increase of uncoupling protein UCP1 expression and expansion of beig

248 ediated by beige adipocytes that express the uncoupling protein UCP1.

249 Moreover, upregulated uncoupling protein UCP4C in intestinal stem cells and en

250 issipates nutritional energy as heat via the uncoupling protein-1 (UCP1) and BAT activity correlates

251 In mammals, uncoupling protein-1 (UCP1) in brown and beige adipocyte

252 Uncoupling protein-1 (UCP1) plays a central role in ener

253 ulation of thermogenic adipocytes expressing uncoupling protein-1 (Ucp1) regulates energy dissipation

254 dipose tissue (WAT) were stained for CB1 and uncoupling protein-1 by immunofluorescent staining.

255 Both CL and Tregs induced much higher UCP-1 (uncoupling protein-1) expression in SAT from females tha

256 mitochondrial uncoupling and thermogenesis (uncoupling protein-1, deiodinase-2, and peroxisome proli

257 t is on the splicing of transcripts encoding uncoupling protein-1, resulting in uncoupled respiration

258 ch encodes the key thermogenic mitochondrial uncoupling protein-1.

259 our group showed an increased expression of uncoupling protein-2 (UCP2) in pancreas from rats with B

260 ion of brownlike adipocytes expressing UCP1 (uncoupling-protein-1) in subcutaneous white adipose tiss

261 Uncoupling proteins (UCPs) regulate energy expenditure i

262 regulators of mitochondrial function are the uncoupling proteins, particularly UCP2.

263 thase as well as by neonatal upregulation of uncoupling proteins.

264 neuronal stimuli, resulting in neurovascular uncoupling, reduced oxygen supply to the brain and metab

265 controls to evaluate: (i) ADMA-mediated NOS uncoupling reduces epithelial production of NO and incre

266 ed to play a role in apoptotic cell death by uncoupling regions important for IP3 binding from the ch

267 Uncoupling respiration from ATP synthesis or increasing

268 lf-life further is ultimately dependent upon uncoupling rFVIII from endogenous VWF.

269 Uncoupling RIG-I deamidation from HSV-1 infection, by en

270 ssary for the initiation of sexual behavior, uncoupling sexual behavior from reproductive status.

271 Thus, uncoupling SPB growth from NE insertion unmasks function

272 otochemical, and electrochemical methods for uncoupling substrate reduction from ATP hydrolysis, whic

273 neurodegenerative disorders, suggesting that uncoupling synaptic activity from nuclear signaling may

274 Uncoupling synergistic interactions between physio-chemi

275 e); end-systolic peak (peak ); and diastolic uncoupling (systolic -diastolic at same volume) during e

276 heterodimer, with beta2AR activation rapidly uncoupling TAS2R14 function ( approximately 65% desensit

277 e without affecting stress behavior, thereby uncoupling the contribution of a specific OXT cluster to

278 the perceived intention of others which, by uncoupling the dynamics of sensorimotor facilitation, co

279 t binds directly to the dynein motor domain, uncoupling the enzymatic and mechanical cycles of the mo

280 and androgen receptor signaling, effectively uncoupling the normal negative feedback between these tw

281 localized to distinct cellular compartments, uncoupling the nuclear and mitochondrial functions of FO

282 However, uncoupling the Shaker K(+) channel's pore domain (PD) fr

283 effector cytokines and cytotoxic functions, uncoupling their proliferation and effector functions.

284 godendrocyte differentiation and maturation, uncoupling them at a transcriptional level and highlight

285 ), to determine the effects of mitochondrial uncoupling therapy on T2D, and the pathogenesis of DPN,

286 m fibrils, thus providing powerful tools for uncoupling these processes and investigating the role of

287 Uncoupling these processes through genome duplications l

288 ion genes, and constructed an in vivo system uncoupling these regulatory genes to show that RappLS20

289 The present work offers two strategies for uncoupling these two processes and converting concerted

290 se T helper 1 (T(H)1) cells by biochemically uncoupling these two processes.

291 e cytosolic Fe-S biogenesis system, and that uncoupling this process triggers leaf-associated Fe-S- a

292 t this helps balance the need for sufficient uncoupling to activate the DNA replication checkpoint wi

293 By uncoupling translation from mRNA localization, we untang

294 esses the underlying basis for mitochondrial uncoupling using VCP knockdown neuroblastoma cell lines,

295 tion and cell migration that were rescued by uncoupling VE-cadDEE from actin.

296 ADH recycling, associated with mitochondrial uncoupling, were not compensated by increased lactic fer

297 e effects, where both heart and RM increased uncoupling whether the assay temperature was acutely cha

298 ed in fatty acid oxidation and mitochondrial uncoupling, which are necessary for development of funct

299 demonstrate that pharmacologic mitochondrial uncoupling with BAM15 has powerful anti-obesity and insu

300 balance leads to nitric oxide synthase (NOS) uncoupling with reduced nitric oxide (NO) formation and