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1 ynthesis of biologically active molecules is underscored.
3 cifying sex-specific aggressive behavior may underscore a genetic mechanism that allows male-type agg
4 lineage progression in the hair follicle and underscore a key role for BMP signaling in driving compl
6 et-acinar axis in pancreatic development and underscore a potential role for the exocrine pancreas in
8 rom the evidence of context-dependencies has underscored a difficulty in establishing a systematic an
9 tion of STK11 with immune-cold behavior, and underscored a potential immunosuppressive role of neutro
12 , clarifies the variable hand phenotype, and underscores a role for anthropometrics in characterizing
13 y neurotransmission and synapse function and underscoring a highly polygenic inheritance pattern that
14 n unpredictable and can be life threatening, underscoring a need for understanding their underlying m
15 saccharides revealed a similar decrease that underscores affinity enhancement by repetitive arrangeme
16 art, the dysregulated excess in this pathway underscores asynchronous Ca(2+) release and arrhythmia.
17 d the non-integrative nature of our approach underscore broader applications in high-throughput array
18 elevance of PRC2-RNA interactions is further underscored by a cardiomyocyte differentiation defect up
19 6A2 in energy balance of PV(+) interneurons, underscored by a decrease in the ATP-to-ADP ratio in Cox
20 lso threaten non-target organisms, a concern underscored by mounting evidence of widespread decline o
21 al role of T cells in tumor control has been underscored by preclinical and clinical studies that obs
23 rategy for electrosynthetic methodologies is underscored by the dramatic differences in yields from c
25 e degree of early impacts of irradiation was underscored by the large number of miRNAs and metabolite
26 acental macrophages (Hofbauer cell [HCs]) is underscored by their appearance 18 d postconception and
27 the nearest-neighbour distances, this study underscored crowding at all surveyed fish landing beache
28 pathway for N-acyl amino acid metabolism and underscore enzymatic division of labor as an enabling st
31 Our results have clinical applicability, underscore how patterns of somatic passenger mutations e
33 f examining age-specific mortality rates and underscores how age standardization can obscure extreme
34 tations of current computational methods and underscores how computational results can be used to inf
36 ing to the complex Abeta-tau interaction and underscore its crucial importance to elucidating disease
37 D dysregulation when telomeres are short and underscore its relevance to the pathophysiology and inte
39 IL2RA plays key biological roles in AML and underscore its value as a potential therapeutic target i
43 inversely correlated with patient survival, underscoring its potential importance for tumor progress
44 thicillin-resistant S. aureus infected rats, underscoring its potential in the context of ventilator-
48 ters represented an important subset of DEG, underscoring PVEC's implication in blood-brain barrier f
51 vious coronaviruses, in this contribution we underscore some of the main unsolved problems, mostly fo
52 , respectively) over approximately 3 months, underscoring switchgrass's effectiveness for BPA removal
56 notype (and presumed ecology) in a stem bird underscores that consolidation to the neornithine-like,
57 Research, the study by Krais and colleagues underscores that DNA damage repair by homologous recombi
59 alternations without competition per se, and underscores that treating triplets in the sequence indep
60 rtially or fully rescued paralog dependency, underscoring that careful selection criteria must be emp
61 for RtoK mutants of P-granule protein LAF-1, underscoring that, to a degree, important LLPS-driving p
66 ncentive salience to reward-paired cues, and underscore the consequences of potential differences in
68 bal macroeconomic burden of breast cancer to underscore the critical importance of improving access t
71 in cancer biology and tumor immunology, and underscore the current advances of clinical trials for n
75 alin family member in hemozoin formation and underscore the heme biomineralization pathway as an attr
79 ecision-making expressed by our participants underscore the importance and challenge of having clear,
81 ical interest to optimize BMT procedures and underscore the importance of accessory, non-HSC to accel
83 l trends and human impacts identified herein underscore the importance of assessing flyway-scale chan
85 cancer risk than BMI at older ages, and they underscore the importance of avoiding excess weight gain
97 ZB and NK cells and p24 production in RM and underscore the importance of inflammatory cytokines in m
98 alth efforts aimed at illness detection, and underscore the importance of integrating temperature sen
102 d within this field, fundamental discoveries underscore the importance of nerve-cancer cross-talk to
105 ss of different spindle-associated genes and underscore the importance of proper cytoskeletal organiz
106 to false-negative COVID-19 test results and underscore the importance of proper training and techniq
108 inst the hyperphosphorylation hypothesis and underscore the importance of revisiting the role of site
110 mits of invariance in object processing, and underscore the importance of studying responses to riche
111 emales, contribute to these associations and underscore the importance of studying such factors, part
113 utic target in neurodegenerative disease and underscore the importance of the mitochondrial unfolded
114 enter through interdomain communications and underscore the importance of the multidomain architectur
115 eural underpinning of attention in aging and underscore the importance of the noradrenergic system in
117 he reliance of IAV on multiple infection and underscore the importance of virus-virus interactions in
119 r-mediated virus entry and efferocytosis and underscore the important contribution of PE in these maj
121 aliber at age 26.Conclusions: These findings underscore the long-lasting effects of the fetal origins
122 cialized RNA binding domain across phyla and underscore the molecular mechanism underlying the functi
124 driving activity in sensorimotor cortex and underscore the necessity of monitoring sleep-wake states
126 us effects on growth and skeletal phenotypes underscore the need for caution in high-dose EGCG supple
127 s support use of the Ayton tool for AGYW and underscore the need for diverse prognostic tools conside
134 ect breeding bird phenology and fitness, and underscore the need to consider sensory pollutants along
135 ojections from the World Health Organization underscore the need to improve outcomes in these patient
136 he cause of tip-to-base conduit widening and underscore the need to study plant hydraulic systems lea
148 uding to support pandas [16], these findings underscore the progress made in China's nascent environm
152 ernative 5' UTRs in neuronal development and underscore the risk of post-transcriptional dysregulatio
156 rts in beach sands and coastal sediments and underscore the role of uncultured taxa in such efforts.
159 rs of genome-level population variation, and underscore the scientific imperative for a broader chara
160 novel genetic loci associated with PWD, and underscore the shared mechanisms of atrial conduction an
164 cytokine-mediated T cell differentiation and underscore the therapeutic potential of transiently inhi
166 nto heavily populated areas around the world underscore the urgency for development of highly effecti
167 nded practices in smaller health systems and underscore the urgent need for improved management of pa
168 scape driving hematological malignancies and underscore the utility of FDA-approved Trk inhibitors fo
173 light recent advances in the field that have underscored the importance of PTMs in the functional reg
174 ellular-, organoid- and human-scale evidence underscored the polygenic architecture underlying DILI v
175 ting in lizards under extreme dry conditions underscored the potential for the hydric environment in
176 f the beneficial microbiota of the host, has underscored the weaknesses in our current treatment para
177 ecapitulates mammalian injury phenotypes and underscores the ability of the stress response to mitiga
178 ence for all-matter spin-state teleportation underscores the capabilities of exchange-coupled spin qu
180 BER/SSBR proteins in multiprotein complexes underscores the coordination of histone/DNA demethylatio
181 nvestigating the impacts of stimulation, and underscores the fact that both the stimulation site, and
182 epurposing the iron-dependent repressor YtgR underscores the fundamental importance of maintaining tr
184 cess of allogeneic stem cell transplantation underscores the immunoresponsive nature of AML, creating
185 ect between preclinical and clinical results underscores the imperative for establishing good animal
186 g use of immune-checkpoint inhibitors (ICIs) underscores the importance of accurate diagnosis and tim
187 pact Goal and associated metrics for success underscores the importance of cardiovascular health and
189 ction of the skin is frequently observed and underscores the importance of developing tolerance induc
191 zophrenia by genome-wide association studies underscores the importance of glycosylation in this dise
194 ZT between two chemically similar compounds underscores the importance of intrinsic defects in engin
195 oform level despite distinct genotype, which underscores the importance of molecular characterization
196 n ion channels in primary hyperaldosteronism underscores the importance of plasma membrane conductanc
197 s intricate epidemiological interactions and underscores the importance of simultaneous monitoring of
198 fferential responses to environmental change underscores the importance of targeted, watershed-specif
199 Together with clinical findings, our work underscores the importance of this variant in viral spre
201 p53 responses such as DNA damage, this study underscores the important role of low basal p53 protein
203 s for joint samples with smaller size, which underscores the necessity of performing representative s
204 conditions can affect male fertility, which underscores the need for a thorough evaluation of patien
205 ises more questions than it could answer and underscores the need for additional investigations on th
207 n mice with equivalent dystrophin expression underscores the need for better understanding of the epi
209 en upper and lower respiratory tract results underscores the need for close monitoring of the clinica
210 d variability of water stress tolerance, and underscores the need for comparative studies that seek t
211 of group meetings was relatively common and underscores the need for DSD models to be flexible and p
213 rounding the diversity of AD pathophysiology underscores the need for holistic systems-based approach
214 ment and prophylaxis of norovirus infections underscores the need for the development of norovirus-sp
216 exposure to oil and/or hypoxia matters, and underscores the need to further investigate the impacts
218 inst NiV and other important paramyxoviruses underscores the need to understand viral entry mechanism
219 provides an evidence-based counterpoint that underscores the potential adverse public health conseque
220 ate reliable lifespan and physiological data underscores the potential of the NemaLife chip to accele
221 an immune system as a cellular swarm, and it underscores the power of collectives throughout nature.
222 traint in many longevity-associated pathways underscores the power of our quantitative approach to de
223 h experiments for a broad range of materials underscores the predictive capability of our method for
226 da endocarditis seen among approximately 40% underscores the seriousness of the infection and need fo
229 Our structural membrane-centric outlook underscores the spatiotemporal principles of membrane an
231 iratory syndrome coronavirus 2 (SARS-CoV-2), underscores the urgency to develop experimental systems
232 protozoan parasite Plasmodium falciparum and underscores the urgent need for new drugs with novel mod
234 ation of MOR in the cell lines we tested and underscores the utility of high-resolution cell-based as
235 ly being targeted in cancer clinical trials, underscoring the challenges inherent in correctly identi
236 e modulators have failed in clinical trials, underscoring the challenges of developing novel rapid-ac
237 ith the most electron-rich indole substrate, underscoring the cruciality of electrophilicity of the h
238 of hallucinogenic compounds is summarized by underscoring the differences between psychedelic and non
239 ween two trimer subunits, Glu456 and Glu483, underscoring the diversity of the catalytic apparatus em
240 ic and excited-state dynamical data, further underscoring the dramatic Fe metal-to-extended ligand CT
241 tinct among closely related cichlid species, underscoring the evolutionary potential of this trait.
242 nted with reactivated chronic toxoplasmosis, underscoring the importance of an intact immune system f
243 ion in the network confers additional gains, underscoring the importance of connectivity within dendr
244 hic facets operate via different mechanisms, underscoring the importance of considering multiple OER
245 is has severely limited such investigations, underscoring the importance of developing improved exper
246 ral phenotypes arising from a common genome, underscoring the importance of epigenetic regulation.
247 ectly predictive of specific CIN mechanisms, underscoring the importance of functional characterizati
248 d feedback inhibition onto pyramidal neurons underscoring the importance of glutamatergic drive onto
249 e increasing rates of antibiotic resistance, underscoring the importance of identifying new targets f
250 ommensal bacteria may inhibit HSV infection, underscoring the importance of studying these microbial
251 gB-activated EGFR mediated SHIP1 activation, underscoring the importance of the interplay between gB-
252 ancient origin of this enzyme in this group, underscoring the important role of viruses in the early
253 pathways representative of each population, underscoring the influence of ancestry on disease mechan
254 n early 2018, 3 mo after Irma's impact, thus underscoring the interspecies differences in nutrient up
255 mpacted by multiple mixtures simultaneously, underscoring the limitations of an exceedance-based appr
256 of the recovered MAGs represented novel taxa underscoring the limited representation of cultured orga
257 lular carcinoma (HCC) are presently limited, underscoring the necessity for further elucidating molec
258 utrophils can cause or worsen tissue injury, underscoring the need for calibration of activation and
259 r acceptance patterns at transplant centers, underscoring the need for greater understanding of how c
260 lth care use and cost burden than HBV alone, underscoring the need for improved screening and treatme
262 surpass current sediment accumulation rates, underscoring the need for including coastal-sediment man
263 ency to only report group-level differences, underscoring the need for inclusion of individual predic
264 chlorinated solvents (e.g., 0.5 to 8 mg/L), underscoring the need of surveying both PRM and THM-enco
265 cal homeostatic cellular functions of SIRT6, underscoring the need to better understand which catalyt
266 lowering the risk for autoimmune disease and underscoring the need to consider host genetics and base
267 nal figures and not for programmatic access, underscoring the need to deposit network maps in communi
268 shallow-versus-deep concentration contrasts, underscoring the often-overlooked role of nutrient distr
269 osits in both the Prnp180Q/196Q and WT mice, underscoring the pivotal role of the GPI-anchor in drivi
270 ic resistance to a notorious woody invader), underscoring the potential for restoring ecological heal
271 can be greater than that in skeletal muscle, underscoring the potential of BMAT to influence systemic
272 usly in tissue culture is also seen in vivo, underscoring the potential utility of H84T as a broad-sp
273 lectively, our finding is an in-depth report underscoring the regulation of VB12 within the beneficia
274 on of transcripts of genes that are induced, underscoring the requirement for proteasome activity at
275 FAO perennialization strategy is reasonable, underscoring the role of perennial crops as a useful com
277 und no evidence of acquired drug resistance, underscoring the safety of rifampin monotherapy for late
279 d homodimerization strengths can be similar, underscoring the significance of RTK heterointeractions
280 end of the An-L bond lengths in both series, underscoring the significance of these delta/phi back-do
281 ompound and scavengers in the aqueous phase, underscoring the significant role of solid surfaces in s
282 e conducive to more efficient tumor control, underscoring the therapeutic potential of antiangiogenic
283 anism of HuR regulating Th17 cell functions, underscoring the therapeutic value of HuR for treatment
285 w NK1R mRNA expression in human spinal cord, underscoring the translational relevance of our findings
286 d commercial importance at the global scale, underscoring the urgency of common options in managing c
287 to overcome resistance remain unidentified, underscoring the urgency to develop reliable immunocompe
288 is currently a shortage of RT-PCR test kits, underscoring the urgent need for alternative methods for
289 salience to stronger attentional orienting, underscoring the utilization of different underlying mec
290 e La(NTMS) is competent to catalyze, further underscoring the value and versatility of lanthanide com
291 s within these key gene ontology categories, underscoring the vulnerability of these corticocortical
292 heterogeneous functions for fibroblasts that underscore their complex molecular signatures and utilit
293 ally activated channel described so far have underscored their diversity while advancing our understa
295 ell as Mycobacterium tuberculosis infection, underscoring their importance in immune regulation.
297 isk factors in genes expressed in microglia, underscoring their therapeutic potential in neurodegener
298 ovide linear indications of vesicle release, underscoring their value for optical quantal analysis.
299 llective efforts to improve upon R-CHOP, and underscore those lessons that might help to reshape our