ライフサイエンスコーパス: understand

1 cific dietary fats and cell fates are poorly understood.

2 ity of their function is achieved are poorly understood.

3 the salt dissolution behavior should be well understood.

4 ease features, and pathophysiology is poorly understood.

5 the genetic etiology of NTDs remains poorly understood.

6 of relative sea level rise (RSLR) is poorly understood.

7 o and development in metazoans remains to be understood.

8 how gamma-TuRC nucleates a MT remains poorly understood.

9 e signaling pathways in plants remain poorly understood.

10 cts the response to immunotherapy are poorly understood.

11 R139 and its signaling mechanisms are poorly understood.

12 s, but their release properties are not well understood.

13 ffect substrate conformations remains poorly understood.

14 nts, yet how this is achieved remains poorly understood.

15 mibiotrophic fungal infection remains poorly understood.

16 wide activity drive action selection is less understood.

17 pathologically relevant conditions is poorly understood.

18 h in Huntington's disease (HD) are not fully understood.

19 n safely operate, but is not comprehensively understood.

20 contributes to PDAC progression is not well understood.

21 e overlooked and their impacts remain poorly understood.

22 nt which significance for immunity is poorly understood.

23 -driven tumor metastasis needs to be further understood.

24 wever, their specific functions are not well-understood.

25 o the migraine phenotype remain incompletely understood.

26 analyses of neural populations are not well understood.

27 monsoonal precipitation and runoff is poorly understood.

28 t the drivers of these patterns are not well understood.

29 these are implemented in the brain is poorly understood.

30 echanisms underlying this process are poorly understood.

31 h taste receptors, processes that are poorly understood.

32 c neovascularization after injury are poorly understood.

33 robial community response has not been fully understood.

34 atory micro-environments remain incompletely understood.

35 cale hydroclimate variability remains poorly understood.

36 up in the cortical hierarchy remains poorly understood.

37 calcium fluctuations are hitherto not fully understood.

38 rain as this learning takes place are poorly understood.

39 ible for these phenomena remain incompletely understood.

40 d in the evolution of bat immunity is poorly understood.

41 the dynamics of PIC components are not fully understood.

42 chanisms that underlie these defects are not understood.

43 reased TB susceptibility in T2D are not well understood.

44 to suppress host innate immunity is not well understood.

45 and consequences thereof are so far not well understood.

46 cell responses is complex and only partially understood.

47 evelopment and function remains incompletely understood.

48 te exposure on an immune system are not well understood.

49 which plants sense temperature are not well understood.

50 ics underlying these phenomena are not fully understood.

51 this function to tumor suppression is poorly understood.

52 contribute to their formation are not fully understood.

53 al selection in normal tissues remain poorly understood.

54 failure for Mycoplasma genitalium is poorly understood.

55 nisms underlying this pathology are not well understood.

56 op-associated genomic stress is still poorly understood.

57 in part because its pathogenesis is not well understood.

58 its pharmacology, however, remains scarcely understood.

59 mechanism of transport into plants is poorly understood.

60 patterns for grants and grantees are poorly understood.

61 6 activity and endosomal function are poorly understood.

62 aspects of protein-DNA binding remain poorly understood(1,2).

63 Here we apply modeling tools to better understand adaptive divergence of whitefish during the p

64 Despite their relevance for understanding aging and cancer, the processes that under

65 ation initiation by OCM opens new avenues to understand alternative translation mechanisms involved i

66 The gained fundamental understanding and demonstrated capabilities enable the r

67 we discuss current challenges for biological understanding and future requirements to overcome them.

68 arch and guideline updates have advanced our understanding and management of ColdU.

69 This study highlights the significance of understanding and optimizing the effects of liposomal na

70 Understanding and visualizing these large multi-dimensio

71 e underlying molecular mechanisms are poorly understood and warrant investigation given the inadequac

72 omote tissue remodelling are beginning to be understood and will be an important research focus in th

73 The pathophysiology of disease is not fully understood, and it may vary by presentation and clinical

74 underlying these processes are incompletely understood, and were proposed to differ between mouse an

75 The reasons are incompletely understood as potential underlying pathomechanisms remai

76 These results are not only valuable for understanding B cell biology, but also have important im

77 on behavior of the solvent molecules must be understood because the electrochemical properties of a s

78 tions supporting this control is crucial for understanding both the nature of computations needed to

79 and centipedes, is a fascinating but poorly understood branch of life, including species with a high

80 This atlas guides our aetiological understanding by associating SN cell type expression pro

81 We propose that to understand causes of sex-biased mortalities, more comple

82 Eco-evolutionary feedbacks may help to understand changes in the adaptive potential after distu

83 century-scale) climatic profiles, and better understand coral persistence, particularly as coral comm

84 mplex process are not well defined and their understanding could offer potential new therapies for CR

85 ion centres and catalytic turnover, but also understanding degradation processes of the photocatalyti

86 In this review, we discuss the current understanding derived from studies of patients with MS a

87 ectures using electronic materials with well-understood electronic transport within such structures w

88 powerful new toolbox they can use to better understand environmental effects, and we illustrate this

89 Understanding evolution requires detailed knowledge of g

90 lex 4 (AP-4) lead to prototypical yet poorly understood forms of childhood-onset and complex heredita

91 lying changes in soil C storage are not well understood, hampering long-term predictions of climate C

92 emerging as an important strategy to better understand host-pathogen interactions.

93 To understand how an accessory subunit (CoREST) enables a c

94 al problem in axon growth and guidance is to understand how cytoplasmic signaling modulates the cytos

95 To understand how fruits regulate flowering in polycarpic p

96 A pressing question is to understand how large-scale cross-linking mass spectromet

97 We seek to understand how locomotor synergies change during develop

98 To better understand how NTRs work, we performed the first compreh

99 We sought to understand how portable current ONT analysis methods are

100 des in the atmosphere, and it is critical to understand how soil greenhouse gas (GHG) emissions and u

101 ge in neurobiology in the 21st century is to understand how the brain adapts with experience.

102 bjected to control, thus, it is important to understand how the reduction of this scavenger guild inf

103 To understand how these compounds alter T cell function, we

104 Research is needed to understand how to monitor immune response to vaccines in

105 ecord provides a window through which we can understand how tree size and traits shape growth respons

106 hese complementary systems is fundamental to understanding how cone-mediated vision is sustained in v

107 properties, which may provide some clues to understanding how melatonin protects against Abeta, and

108 Understanding how RGF1 regulates the development of the

109 Understanding how species have responded to past climate

110 Our findings are crucial for understanding how the brain regulates information flow a

111 Understanding how their synthesis is regulated is crucia

112 Thus, understanding how variants of IFI16 and AIM2 contribute

113 however, are not fully understood, nor is it understood how microstructure and mechanics change with

114 However, it is not fully understood how plants control light-dependent FAS regula

115 These regions were compared to understand if sex determination is controlled via the sa

116 ian BST-2 with avian viruses is important in understanding innate antiviral defenses in birds.IMPORTA

117 cular level can provide valuable insights in understanding intrinsic reaction pathways, for affording

118 Also, the understanding is so far limited to the results based on

119 tiology of type 1 diabetes (T1D) is not well understood, it is believed to comprise both genetic and

120 ve heterochromatin state are reasonably well understood, less is known about the requirements for its

121 Understanding life history strategies in deep-sea enviro

122 Specifically, we understand little about how taxonomic and functional div

123 e importance of different memory systems for understanding maladaptive use, clinical research parsing

124 The structure provides a framework for understanding mechanisms of trans-histone cross-talk and

125 In the setting of human health, understanding metabolic changes within bacteria in envir

126 espectively, which may provide insights into understanding miRNA signaling underlying cancer cell met

127 echanical properties, however, are not fully understood, nor is it understood how microstructure and

128 A comprehensive understanding of African North American biohistory is a

129 length scales, are used to gain fundamental understanding of all processes leading to catalytic acti

130 Many gaps in our understanding of Alzheimer's disease remain despite inte

131 cross the globe, significantly advancing our understanding of animal movement [1, 2].

132 for developing a vastly improved mechanistic understanding of animal movements and their roles in eco

133 ar, there have been numerous advances in our understanding of arrhythmia mechanisms, diagnosis, and n

134 is finding has implications not only for our understanding of basic mechanisms of iron biology but al

135 al function of most SMs remains obscure, but understanding of both the activation of silent gene clus

136 A better understanding of bradykinesia pathophysiology will serve

137 ped the field of cancer biology and advanced understanding of cancer pathophysiology.

138 tion algorithms, and potentially enhance our understanding of CD4(+) T cell recognition.

139 n interactions (PPIs) is fundamental for the understanding of cellular machineries.

140 A detailed and quantitative understanding of cis-clustering has been hindered by a l

141 th the primary objective of gaining a better understanding of determinants of house dust Pb bioavaila

142 e informative for developing a more profound understanding of disease pathogenesis and ultimately tar

143 non-invasive polysomnography; however, basic understanding of dog sleep patterns remains poorly chara

144 ns of immune-relevant proteins; however, our understanding of electrophile-sensitive cysteines in the

145 e model's substantial complexity informs our understanding of false memories or of the development of

146 and optoelectronic devices, yet fundamental understanding of film formation, key to optimizing these

147 In this work, mechanistic understanding of flavin-catalyzed oxidation reactions, i

148 ional connectivity methods for improving our understanding of functional neuroanatomy and disruptions

149 PR/Cas9 technologies have revolutionized our understanding of gene function in complex biological set

150 le information and can be applied to improve understanding of global change.

151 enabled biochemical studies that deepen our understanding of how bacterial cell wall enzymes coopera

152 Yet our understanding of how cancer cells sense and convert mech

153 By contrast, an understanding of how effectors manipulate nonimmunity pa

154 dies supporting this function, a mechanistic understanding of how Msp1 extracts its substrates is sti

155 Our study not only deepened our understanding of how ratio-sensing is achieved in yeast

156 Our understanding of how rotavirus (RV) subverts host innate

157 ponses to perceptual figures, we have a poor understanding of how the early visual system contributes

158 . microporus should contribute to the better understanding of how the fungus is able to facilitate wo

159 al models with brain activity and pushes our understanding of human brain function further along the

160 Improved understanding of influenza antigen structure and immunob

161 ex, which has important implications for our understanding of information processing across different

162 ny areas of cancer research and improved our understanding of intratumor heterogeneity, the tumor mic

163 A fundamental understanding of ion transport behavior in wood-based st

164 As a result of our incomplete understanding of its pathophysiology, functional dyspeps

165 sly by oxidative catabolism of heme, and the understanding of its spatial and temporal sensing at the

166 studies have implications in furthering our understanding of JAM in cancer and provide a paradigm fo

167 This review describes the current understanding of LapA-mediated biofilm formation by P. f

168 ng descriptors that can facilitate a general understanding of membrane-mediated ligand binding.

169 Our results provide a mechanistic understanding of N(2)O production in eukaryotic phototro

170 the molecular underpinnings and mechanistic understanding of nanotoxicity.

171 These findings further our understanding of neurodevelopmental trajectories in TS a

172 Advancing understanding of neuron-cancer interactions will elucida

173 This challenges our understanding of organismal functioning, as the link amo

174 These results advance the understanding of poorly characterized ER stress-dependen

175 protein-binding residues (PBRs) improves our understanding of protein-protein interactions, contribut

176 This study advances our fundamental understanding of redox mechanisms in disordered rocksalt

177 n essential step toward a more comprehensive understanding of resistance spread.

178 Summarization of the current understanding of retinal changes that have been identifi

179 spital episodes in Scotland has enhanced our understanding of secular trends of EGS, including demogr

180 A comprehensive understanding of structure-reactivity relationships is c

181 e remained elusive due to a poor mechanistic understanding of studied phenotypes.

182 nd de novo immunity will be critical for our understanding of susceptibility to and the natural cours

183 these studies do not reflect a comprehensive understanding of SWI/SNF complex regulation.

184 of leukaemia, this study is important to our understanding of T-ALL.

185 gh there is still much to learn, our current understanding of tetrapyrrole biogenesis represents a re

186 ptome, and functional assays advance general understanding of the Antarctic green algae and offer pot

187 n coordination complexes affords us a better understanding of the assembly and function of metalloclu

188 initiatives by providing a locally relevant understanding of the causes of mangrove loss.

189 equencing revolutionized the epidemiological understanding of the clusters; it also underlined the ri

190 lly viable devices, but it also sharpens our understanding of the design problems solved by evolution

191 tic resistance, together with our increasing understanding of the detrimental effects conferred by br

192 meningiomas is presented alongside existing understanding of the embryological origins for the menin

193 information lays the groundwork for improved understanding of the endogenous opioid system that will

194 To advance our understanding of the etiology of blinding diseases, we u

195 This has important implications for our understanding of the evolution of vision.

196 oach and results thus contribute to a deeper understanding of the evolutionary dynamics resulting fro

197 servations in the hope of achieving a better understanding of the fate and impact of micro- and/or na

198 lved complex cognitive skills but a detailed understanding of the full scope of their cognition was,

199 wn about the existence of T-R conflicts, our understanding of the genetic and temporal nature of how

200 An understanding of the genetic basis of sex determination

201 To increase understanding of the genomic landscape of acral melanoma

202 Understanding of the harm to health from lifestyle cause

203 It will also allow for a better understanding of the immune response induced after IDV i

204 Our results add to our understanding of the initial peopling of the Caribbean a

205 For a deeper understanding of the levan synthesis reaction, we determ

206 Together, these findings advance our understanding of the mechanisms by which the early syner

207 An improved understanding of the mechanisms underlying UC has led to

208 A confluence of detailed understanding of the molecular basis of HbF gene express

209 Here we review the current understanding of the molecular basis of telomeropathies

210 This work furthers our understanding of the molecular mechanism of CD81 cholest

211 NA chaperone, significant gaps remain in our understanding of the molecular mechanisms ProQ uses to i

212 Here, we review current understanding of the molecular mechanisms underlying hya

213 s study offers an interesting outlook in the understanding of the necessity of epitope clusters for e

214 There is little understanding of the participation of each TRPC in each

215 terogeneous pigment remain unknown, limiting understanding of the properties of its light-responsive

216 However, a functional understanding of the putative PC-1/PC-2 polycystin compl

217 le to reovirus infection and expands current understanding of the receptors on microglial cells that

218 ysing these data but must be applied with an understanding of the relevant biological and computation

219 nate immunity, and may have relevance to our understanding of the responses of ecologically important

220 Understanding of the role of focal inflammation, a treat

221 To enhance our understanding of the role of lipids in regulation of lif

222 With the increasing understanding of the roles of macrophage immunometabolis

223 Our understanding of the safety and efficacy of cannabis has

224 hin the OFC is fundamental for a mechanistic understanding of the sequelae for several psychiatric di

225 ed XPA missense mutations, and contribute to understanding of the structure and mechanical action of

226 Progress in these reports provides a further understanding of the structure-function relationships of

227 ost terrestrial ecosystem processes, we lack understanding of their interactive effects on ecosystem

228 BsAbs' epitopes not only allows for detailed understanding of their mechanism of actions but also gui

229 Better understanding of these issues, especially effects of con

230 Improved understanding of these risks could meaningfully improve

231 and reverse genetics have contributed to our understanding of this important class of microalgae in t

232 I review theoretical understanding of this phenomenon (sometimes referred to

233 Having an understanding of this remarkable process may help the de

234 stems Immunology' has already influenced our understanding of tumor immunology and immunotherapy.

235 lation and highlight opportunities to better understand OSN modulation mechanisms and their relations

236 Mentalizing is the capacity to understand others and oneself in terms of internal menta

237 (MCI) and Alzheimer's disease (AD) is poorly understood, particularly at early stages preceding neuro

238 How this resistance is mediated is poorly understood, particularly during long-term exposure.

239 of clinical trials in an expedited effort to understand, prevent, and treat this disease.

240 iocins to translocate into cells by a poorly understood process.

241 Nonenveloped virus entry is an incompletely understood process.

242 ecific manner, which is vital for accurately understanding protein function in cellular processes.

243 Therefore, it is important to understand salinity distributions and compare defined ba

244 opment of the root meristem is essential for understanding stem cell function.

245 gy, but also have important implications for understanding tetraspanin function generally.

246 To understand the altered mobility of an oncogenic KRAS4b,

247 Further research is needed to understand the clinical importance of the findings.

248 However, further research is needed to understand the clinical importance of the observed diffe

249 Thus, our study helps understand the comprehensive regulatory mechanisms for c

250 diagnosis and environmental microbiology, to understand the contribution of metabolically active bact

251 To understand the determinants of ARO colonization on NF ad

252 8,457 somatic structural variations (SVs) to understand the distributions and effects of SVs across T

253 To understand the effects of multisite phosphorylation on t

254 mine their complement of ion channels and to understand the function of biological circuits.

255 ew highlights future opportunities to better understand the functional significance of genetic varian

256 Here, we set out to understand the heterogeneity of HbF activation by develo

257 Further work is required to understand the intrapulmonary pharmacokinetics of first-

258 ges for a variety of brain regions; and (ii) understand the mechanism through which verubecestat migh

259 efficient cause-effect experimental model to understand the mechanisms of direct virus-induced neural

260 Further studies are needed to understand the mechanisms underlying these brain abnorma

261 er, no study has systematically attempted to understand the molecular basis of imaging traits based o

262 pathogenesis has hampered efforts to better understand the molecular interactions governing disease

263 rend in CNS disease biology is to attempt to understand the neural-cell-immune interaction to investi

264 To better understand the potential for metabolites to influence po

265 alyses of viral transcript levels to further understand the roles of these decay pathways in KSHV gen

266 Further research is needed to understand the source of these associations with a perso

267 This study will enable other researchers in understanding the B. microti biology, host modulation an

268 A heuristic neurobiological framework for understanding the bidirectional relationship between abn

269 currently recognized, with implications for understanding the character evolution in theropods.

270 Understanding the circumstances of the undeclared 2017 n

271 This spectrum pertains to understanding the disease itself, which is challenging d

272 epression symptomatology and a more complete understanding the diversity of molecular changes that oc

273 Understanding the driving mechanisms of the interannual

274 Our framework may also help toward understanding the effects of habituation in other more s

275 Understanding the features underlying induction of these

276 Understanding the mechanisms of HPgammaCD-induced cellul

277 Understanding the mechanisms underlying this phenomenon

278 They provide a platform for understanding the pathogenesis of macular degeneration a

279 nces in animal models that are important for understanding the pathogenesis of SARS-CoV-2, vaccine de

280 pathogenesis, there is increased interest in understanding the potential clinical utility of a geneti

281 Understanding the potential relationship between these a

282 Understanding the power and limitations of various read

283 egulate reward, motivation, and food intake, understanding the role of opioid signaling within the OF

284 Understanding the thermodynamics of paramagnetic transit

285 the proteins is in itself not sufficient to understand their architectural properties.

286 direct imaging of EpiSCs after MI to better understand their biology, but also may permit the cell-s

287 ain mechanisms, but we are only beginning to understand their mechanistic basis.

288 cence and floral development is essential to understand their role in the evolutionary origin of deve

289 their effects are, therefore, important for understanding these patterns.

290 s and provide a better physical framework to understand this important phenomenon.

291 Here, we highlight the developments in understanding TIM3 biology, including novel ligand ident

292 forming dense droplets that are increasingly understood to be important for cellular function.

293 lls, which offers new perspectives to better understand virus-glycan interactions in physiologically

294 radients provides a convenient heuristic for understanding what drives and maintains diversity.

295 Second, efforts have been made to understand "what" the dorsolateral striatum (DLS) does f

296 Consequently, it is important to understand whether SMC continues to provide a high level

297 To understand which irregular corneal parameters determine

298 e findings have significant implications for understanding why a hypomorphic loss of BCCIP functions

299 moting excessive activation are incompletely understood, with limited experimental models to investig

300 des, which advance fundamental knowledge for understanding xenon chemistry and physics mechanisms for