ライフサイエンスコーパス: understanding

1 d antiviral activity but limited mechanistic understanding.

2 es aimed at improving agricultural yield and understanding adaptive processes.

3 These results provide a proof of concept for understanding age-related vascular changes and imply tha

4 Despite their relevance for understanding aging and cancer, the processes that under

5 The gained fundamental understanding and demonstrated capabilities enable the r

6 we discuss current challenges for biological understanding and future requirements to overcome them.

7 ical reasoning is present in infancy and aid understanding and learning about the social environment.

8 arch and guideline updates have advanced our understanding and management of ColdU.

9 This study highlights the significance of understanding and optimizing the effects of liposomal na

10 its complications is, therefore, critical to understanding and treating the disease.

11 However, there is a need for a better understanding and user instructions on the influence of

12 Understanding and visualizing these large multi-dimensio

13 Predicting, controlling, understanding, and elucidating the phase transition from

14 are primarily expected to target the cortex, understanding atrophy across this region is essential.

15 These results are not only valuable for understanding B cell biology, but also have important im

16 Understanding bacterial defense and survival strategies

17 ortance of nonequilibrium thermodynamics for understanding biological dynamics and functions.

18 tions supporting this control is crucial for understanding both the nature of computations needed to

19 This atlas guides our aetiological understanding by associating SN cell type expression pro

20 This review summarises advances in understanding C. difficile germination and outlines curr

21 can lead to precise molecular mechanisms for understanding complex human diseases, like cancer.

22 shed analytical tool capable of defining and understanding complex tissues by determining the spatial

23 mplex process are not well defined and their understanding could offer potential new therapies for CR

24 This review summarises recent progress in understanding crassulacean acid metabolism (CAM) systems

25 ion centres and catalytic turnover, but also understanding degradation processes of the photocatalyti

26 In this review, we discuss the current understanding derived from studies of patients with MS a

27 ico is a challenge that has implications for understanding diseases as well as industrial application

28 Understanding evolution requires detailed knowledge of g

29 dies have attempted to develop a mechanistic understanding for the observed behaviors, predominantly

30 al findings, gaps and inconsistencies in our understanding have remained.

31 approach has led to substantial progress in understanding host-microbiota interactions.

32 hese complementary systems is fundamental to understanding how cone-mediated vision is sustained in v

33 s of catalytic intermediates broadly and for understanding how copper active sites achieve activation

34 Understanding how genetics influence mammographic featur

35 Understanding how leukocytes are produced and how they c

36 properties, which may provide some clues to understanding how melatonin protects against Abeta, and

37 Understanding how oncogenic mutations rewire regulatory-

38 This study provides a foundation for understanding how pharmacologically diverse and clinical

39 Understanding how RGF1 regulates the development of the

40 Understanding how species have responded to past climate

41 w ruthenium complexes provide a platform for understanding how strong trans effect ligands and redox-

42 Our findings are crucial for understanding how the brain regulates information flow a

43 Understanding how their synthesis is regulated is crucia

44 Thus, understanding how variants of IFI16 and AIM2 contribute

45 lem, thus providing an important step toward understanding human sequential decision making.

46 ian BST-2 with avian viruses is important in understanding innate antiviral defenses in birds.IMPORTA

47 However, fundamental understanding into the structural characteristics respon

48 cular level can provide valuable insights in understanding intrinsic reaction pathways, for affording

49 Such improved understanding is critical to the development of new anti

50 Also, the understanding is so far limited to the results based on

51 Understanding life history strategies in deep-sea enviro

52 e importance of different memory systems for understanding maladaptive use, clinical research parsing

53 This understanding may lead to new targets or approaches for

54 d progenitors, with broader implications for understanding mechanisms for stem cell maintenance, nich

55 The structure provides a framework for understanding mechanisms of trans-histone cross-talk and

56 In the setting of human health, understanding metabolic changes within bacteria in envir

57 espectively, which may provide insights into understanding miRNA signaling underlying cancer cell met

58 Our work fits within the broader context of understanding neural computations as dynamics over relat

59 eterogeneous infectiousness is important for understanding NoV transmission dynamics.

60 the Drosophila of frustrated magnetism, our understanding of a pair of coupled zigzag chains (frustr

61 y studies that have advanced the mechanistic understanding of AD, single cell-based molecular alterat

62 l therapeutic approaches as well as a deeper understanding of ADP-ribosylation as a whole.

63 models have contributed significantly to our understanding of AF and some therapeutic options.

64 A comprehensive understanding of African North American biohistory is a

65 This work improves our understanding of aggregated-state photoluminescence, con

66 An understanding of alcohol's acute neural effects could au

67 length scales, are used to gain fundamental understanding of all processes leading to catalytic acti

68 Many gaps in our understanding of Alzheimer's disease remain despite inte

69 cross the globe, significantly advancing our understanding of animal movement [1, 2].

70 for developing a vastly improved mechanistic understanding of animal movements and their roles in eco

71 In order to gain a more comprehensive understanding of APOE4's role in AD pathogenesis, we per

72 ar, there have been numerous advances in our understanding of arrhythmia mechanisms, diagnosis, and n

73 To advance the scientific understanding of bacteria-driven mercury (Hg) transforma

74 is finding has implications not only for our understanding of basic mechanisms of iron biology but al

75 utline recent findings that provide a deeper understanding of both parenchymal microglia and extrapar

76 al function of most SMs remains obscure, but understanding of both the activation of silent gene clus

77 These novel findings provide a better understanding of both the genetic and the physiological

78 A better understanding of bradykinesia pathophysiology will serve

79 ic and epigenetic data can facilitate better understanding of brainstem gliomagenesis and classificat

80 how they have (and will) contributed to our understanding of cancer biology as well as to the develo

81 ession and thus modeling it will advance our understanding of cancer growth dynamics and response to

82 ped the field of cancer biology and advanced understanding of cancer pathophysiology.

83 tion algorithms, and potentially enhance our understanding of CD4(+) T cell recognition.

84 n interactions (PPIs) is fundamental for the understanding of cellular machineries.

85 versatile method that improves systems-level understanding of cellular organization in health and dis

86 review, we summarize recent progress in the understanding of chemically mediated bacterial-fungal in

87 Nevertheless, the current understanding of CHIKV-host interactions and adaptabilit

88 l-type-specific resolution have expanded the understanding of circuit changes underlying experience-d

89 A detailed and quantitative understanding of cis-clustering has been hindered by a l

90 th the primary objective of gaining a better understanding of determinants of house dust Pb bioavaila

91 st focus, leading to significant advances in understanding of disease mechanisms, widely adopted guid

92 importance of antigen discovery for improved understanding of disease mechanisms.

93 e informative for developing a more profound understanding of disease pathogenesis and ultimately tar

94 Understanding of disease seasonal synchronization is ess

95 murine satellite cell pool, a comprehensive understanding of distinct subpopulations and their funct

96 non-invasive polysomnography; however, basic understanding of dog sleep patterns remains poorly chara

97 Advances in our understanding of drug block and inactivation mechanisms

98 and tissue shape will generate an integrated understanding of early embryogenesis and new strategies

99 ns of immune-relevant proteins; however, our understanding of electrophile-sensitive cysteines in the

100 e model's substantial complexity informs our understanding of false memories or of the development of

101 and optoelectronic devices, yet fundamental understanding of film formation, key to optimizing these

102 In this work, mechanistic understanding of flavin-catalyzed oxidation reactions, i

103 ional connectivity methods for improving our understanding of functional neuroanatomy and disruptions

104 PR/Cas9 technologies have revolutionized our understanding of gene function in complex biological set

105 it also provides opportunities for improving understanding of genetic mechanisms underlying the devel

106 le information and can be applied to improve understanding of global change.

107 enabled biochemical studies that deepen our understanding of how bacterial cell wall enzymes coopera

108 Yet our understanding of how cancer cells sense and convert mech

109 Developing a thorough understanding of how ectotherm physiology adapts to diff

110 By contrast, an understanding of how effectors manipulate nonimmunity pa

111 dies supporting this function, a mechanistic understanding of how Msp1 extracts its substrates is sti

112 Second, we need a better mechanistic understanding of how physical conditions in streams driv

113 Our study not only deepened our understanding of how ratio-sensing is achieved in yeast

114 Our understanding of how rotavirus (RV) subverts host innate

115 ponses to perceptual figures, we have a poor understanding of how the early visual system contributes

116 . microporus should contribute to the better understanding of how the fungus is able to facilitate wo

117 Remaining gaps in knowledge include an understanding of how the TTFL proteins behave individual

118 llergen-specific immunotherapy outcomes, but understanding of how these integrate to maintain immunol

119 al models with brain activity and pushes our understanding of human brain function further along the

120 Improved understanding of influenza antigen structure and immunob

121 ex, which has important implications for our understanding of information processing across different

122 ny areas of cancer research and improved our understanding of intratumor heterogeneity, the tumor mic

123 A fundamental understanding of ion transport behavior in wood-based st

124 properties and provide enhanced fundamental understanding of ionization that could enable novel memb

125 his review summarises recent advances in our understanding of its clinical presentation, pathomechani

126 As a result of our incomplete understanding of its pathophysiology, functional dyspeps

127 sly by oxidative catabolism of heme, and the understanding of its spatial and temporal sensing at the

128 studies have implications in furthering our understanding of JAM in cancer and provide a paradigm fo

129 This review describes the current understanding of LapA-mediated biofilm formation by P. f

130 These findings establish a mechanistic understanding of LBL-lipid interactions and create a mod

131 ion of monitoring programs for improving our understanding of marine ecosystems, with the goal of inf

132 ng descriptors that can facilitate a general understanding of membrane-mediated ligand binding.

133 coding signaling selectivity and advance our understanding of molecular recognition principles.

134 Our results provide a mechanistic understanding of N(2)O production in eukaryotic phototro

135 the molecular underpinnings and mechanistic understanding of nanotoxicity.

136 These findings further our understanding of neurodevelopmental trajectories in TS a

137 Advancing understanding of neuron-cancer interactions will elucida

138 These findings provide an atomistic understanding of non-volatile switching and open a new d

139 nes, offering new functional and mechanistic understanding of NONO in stem cell functions, lineage co

140 This challenges our understanding of organismal functioning, as the link amo

141 These results advance the understanding of poorly characterized ER stress-dependen

142 protein-binding residues (PBRs) improves our understanding of protein-protein interactions, contribut

143 e use of model systems to enable mechanistic understanding of RAD51 cellular roles.

144 component nanocrystals requires atomic-level understanding of reaction kinetics.

145 This study advances our fundamental understanding of redox mechanisms in disordered rocksalt

146 n essential step toward a more comprehensive understanding of resistance spread.

147 Summarization of the current understanding of retinal changes that have been identifi

148 spital episodes in Scotland has enhanced our understanding of secular trends of EGS, including demogr

149 Understanding of spatiotemporal transmission of infectio

150 Contributions to a network neuroscience understanding of status perception and implications for

151 A comprehensive understanding of structure-reactivity relationships is c

152 e remained elusive due to a poor mechanistic understanding of studied phenotypes.

153 nd de novo immunity will be critical for our understanding of susceptibility to and the natural cours

154 these studies do not reflect a comprehensive understanding of SWI/SNF complex regulation.

155 of leukaemia, this study is important to our understanding of T-ALL.

156 gh there is still much to learn, our current understanding of tetrapyrrole biogenesis represents a re

157 ptome, and functional assays advance general understanding of the Antarctic green algae and offer pot

158 n coordination complexes affords us a better understanding of the assembly and function of metalloclu

159 mi-arid ecosystems around the world, yet our understanding of the belowground impacts of this phenome

160 initiatives by providing a locally relevant understanding of the causes of mangrove loss.

161 equencing revolutionized the epidemiological understanding of the clusters; it also underlined the ri

162 lly viable devices, but it also sharpens our understanding of the design problems solved by evolution

163 tic resistance, together with our increasing understanding of the detrimental effects conferred by br

164 This work advances our understanding of the dynamics and functions of EMT plast

165 fluencing animal intake can provide a better understanding of the dynamics of the pasture ecosystem a

166 meningiomas is presented alongside existing understanding of the embryological origins for the menin

167 information lays the groundwork for improved understanding of the endogenous opioid system that will

168 To advance our understanding of the etiology of blinding diseases, we u

169 This work alters our understanding of the events that drive the activation of

170 This has important implications for our understanding of the evolution of vision.

171 oach and results thus contribute to a deeper understanding of the evolutionary dynamics resulting fro

172 servations in the hope of achieving a better understanding of the fate and impact of micro- and/or na

173 lved complex cognitive skills but a detailed understanding of the full scope of their cognition was,

174 Advances in our understanding of the fundamental chemistry underlying th

175 wn about the existence of T-R conflicts, our understanding of the genetic and temporal nature of how

176 An understanding of the genetic basis of sex determination

177 Understanding of the genetic basis of this disorder high

178 association studies have revolutionized our understanding of the genetic underpinnings of cardiometa

179 To increase understanding of the genomic landscape of acral melanoma

180 Understanding of the harm to health from lifestyle cause

181 this burden but is predicated on a detailed understanding of the immensely complex relationship betw

182 It will also allow for a better understanding of the immune response induced after IDV i

183 Our results add to our understanding of the initial peopling of the Caribbean a

184 on and genome function require comprehensive understanding of the interactome networks that mediate g

185 These results enhance our understanding of the kogiid gut microbiome and may provi

186 For a deeper understanding of the levan synthesis reaction, we determ

187 Together, these findings advance our understanding of the mechanisms by which the early syner

188 Therefore, a better understanding of the mechanisms controlled by MAPK pathw

189 ts into beta-PE biosynthesis and advance our understanding of the mechanisms guiding lyase isomerases

190 An improved understanding of the mechanisms underlying UC has led to

191 Our understanding of the microorganisms involved in in situ

192 A confluence of detailed understanding of the molecular basis of HbF gene express

193 Here we review the current understanding of the molecular basis of telomeropathies

194 rage by MALDI-2 can also help to improve our understanding of the molecular basis of tumor developmen

195 This work furthers our understanding of the molecular mechanism of CD81 cholest

196 NA chaperone, significant gaps remain in our understanding of the molecular mechanisms ProQ uses to i

197 Here, we review current understanding of the molecular mechanisms underlying hya

198 To achieve this goal, we need a clearer understanding of the molecular pathways that underlie th

199 Our understanding of the molecular regulation of aging and a

200 s study offers an interesting outlook in the understanding of the necessity of epitope clusters for e

201 hese results lay the foundation for a better understanding of the neuroanatomical basis of the stress

202 There is little understanding of the participation of each TRPC in each

203 However, our understanding of the process of wood growth and its resp

204 terogeneous pigment remain unknown, limiting understanding of the properties of its light-responsive

205 However, a functional understanding of the putative PC-1/PC-2 polycystin compl

206 This detailed understanding of the receptor activation may aid in the

207 le to reovirus infection and expands current understanding of the receptors on microglial cells that

208 rly defined exposure variables to strengthen understanding of the relationship between rainfall and d

209 Therefore, it is important to gain a better understanding of the relative contribution of different

210 ysing these data but must be applied with an understanding of the relevant biological and computation

211 KV replication and further contribute to our understanding of the requirements for autophagy during f

212 nate immunity, and may have relevance to our understanding of the responses of ecologically important

213 Understanding of the role of focal inflammation, a treat

214 To enhance our understanding of the role of lipids in regulation of lif

215 With the increasing understanding of the roles of macrophage immunometabolis

216 Our understanding of the safety and efficacy of cannabis has

217 highly demanding, mostly due to insufficient understanding of the self-assembly process at the nanosc

218 hin the OFC is fundamental for a mechanistic understanding of the sequelae for several psychiatric di

219 ed XPA missense mutations, and contribute to understanding of the structure and mechanical action of

220 Progress in these reports provides a further understanding of the structure-function relationships of

221 is review, we discuss recent advances in the understanding of the UPR, emphasizing conserved UPR elem

222 ost terrestrial ecosystem processes, we lack understanding of their interactive effects on ecosystem

223 BsAbs' epitopes not only allows for detailed understanding of their mechanism of actions but also gui

224 from expert knowledge and allow a biological understanding of their output.

225 2019 (COVID-19) have been described, but the understanding of their pathophysiologic causes and neuro

226 In turn, our understanding of their structure and evolution depends c

227 Yet understanding of these factors has been necessarily qual

228 Better understanding of these issues, especially effects of con

229 However, a deep understanding of these phenomena and their redox chemist

230 onal theory (DFT) to develop a more complete understanding of these photoinduced synthetic transforma

231 Improved understanding of these risks could meaningfully improve

232 ch studies have yielded a strong mechanistic understanding of this disease.

233 and reverse genetics have contributed to our understanding of this important class of microalgae in t

234 I review theoretical understanding of this phenomenon (sometimes referred to

235 ng the outstanding questions critical to our understanding of this potential risk to food safety.

236 Having an understanding of this remarkable process may help the de

237 A better understanding of this structure, and how it plays a role

238 hat EBOV results in severe organ damage, our understanding of tissue injury in the liver, adrenal gla

239 The findings contribute to our understanding of tuberculosis control and have implicati

240 stems Immunology' has already influenced our understanding of tumor immunology and immunotherapy.

241 de a systematic toolkit to help maximize our understanding of viral roles in health and disease.

242 s, particularly APT, because of insufficient understanding of void imaging.

243 veloped for species diversity to further our understanding of what exactly phytochemical diversity is

244 een proteins follows complex mechanisms, the understanding of which can substantially advance drug di

245 l-world problems have become ubiquitous, our understanding of why they are so effective is lacking.

246 This review summarizes current understandings of the tumor microenvironment and interce

247 Understanding our unique social psychology requires acco

248 Understanding participant behaviour could support better

249 ecific manner, which is vital for accurately understanding protein function in cellular processes.

250 dilution strategy and will fill a gap in our understanding, providing insights through quantitative e

251 highlighted as an apt comparative model for understanding RGC decussation, as albinos have a reduced

252 opment of the root meristem is essential for understanding stem cell function.

253 gy, but also have important implications for understanding tetraspanin function generally.

254 To move forward, we must proceed by understanding that cats are not exclusively pets or pest

255 Global financial crises have led to the understanding that classical econometric models are limi

256 ives, the 2030 Impact Goal is anchored in an understanding that to achieve cardiovascular health for

257 This study will enable other researchers in understanding the B. microti biology, host modulation an

258 A heuristic neurobiological framework for understanding the bidirectional relationship between abn

259 s, a large body of literature has focused on understanding the biological barriers that hinder tissue

260 vivo has significantly hampered progress in understanding the biological functions of this scaffold

261 currently recognized, with implications for understanding the character evolution in theropods.

262 Understanding the circumstances of the undeclared 2017 n

263 Understanding the context and analyzing the role of rele

264 Understanding the controls on the distribution and magni

265 This spectrum pertains to understanding the disease itself, which is challenging d

266 epression symptomatology and a more complete understanding the diversity of molecular changes that oc

267 Understanding the driving mechanisms of the interannual

268 ited cohort provide a critical first step in understanding the earliest immune response to HIV-1 and

269 Our framework may also help toward understanding the effects of habituation in other more s

270 Understanding the features underlying induction of these

271 Thus, understanding the fundamental kinetics of MOF-based mole

272 Understanding the mechanism of action (MOA) of bioactive

273 Understanding the mechanisms of HPgammaCD-induced cellul

274 Understanding the mechanisms of these processes may enab

275 Understanding the mechanisms underlying this phenomenon

276 populations and discuss the implications for understanding the origins of senescence, frailty, and mo

277 They provide a platform for understanding the pathogenesis of macular degeneration a

278 nces in animal models that are important for understanding the pathogenesis of SARS-CoV-2, vaccine de

279 among psychiatric disorders is important for understanding the pathophysiology.

280 pathogenesis, there is increased interest in understanding the potential clinical utility of a geneti

281 Understanding the potential relationship between these a

282 Physicians need to become competent in understanding the potential risks and benefits of autono

283 Understanding the power and limitations of various read

284 iron solubility and microbial availability, understanding the processes governing ligand dynamics is

285 Understanding the processes underlying normal, impaired,

286 enomic data across populations is central to understanding the role of genetic factors in health and

287 egulate reward, motivation, and food intake, understanding the role of opioid signaling within the OF

288 ogeneity and poses challenging questions for understanding the speciation process for oceanic zooplan

289 These results may help toward understanding the strength and erodibility of natural so

290 Understanding the structure and properties of the occlus

291 Understanding the thermodynamics of paramagnetic transit

292 is complexity poses formidable challenges to understanding the underlying molecular basis for each of

293 , deciding which interventions to pursue and understanding their relative co-benefits with and trade-

294 Understanding these patterns is critical for predicting

295 their effects are, therefore, important for understanding these patterns.

296 Here, we highlight the developments in understanding TIM3 biology, including novel ligand ident

297 radients provides a convenient heuristic for understanding what drives and maintains diversity.

298 e findings have significant implications for understanding why a hypomorphic loss of BCCIP functions

299 or interstate characteristics contribute to understanding why scope of practice differences exist.

300 des, which advance fundamental knowledge for understanding xenon chemistry and physics mechanisms for