ライフサイエンスコーパス: understanding of how

1 sulting series of NCs can provide insightful understanding of how a single atom affects the structure

2 Our findings provide a molecular understanding of how a single mutation in the KLF1 zinc

3 These structural observations advance the understanding of how a single protein, CDTb, can mediate

4 Our study provides a mechanistic understanding of how a wetland species persists, and eve

5 intercellular levels in short timescales, an understanding of how Abeta fibrillization usually starts

6 s been observed, we often lack a mechanistic understanding of how adaptation happens.

7 However, our understanding of how adaptive evolution allows species t

8 cificity remain error prone due to a lack of understanding of how adjacent fingers influence each oth

9 We propose that a complete understanding of how ageing affects haematopoiesis depen

10 en together, these findings provide in-depth understanding of how alkyl-PTE lesions are recognized by

11 as a maintenance strategy have enhanced our understanding of how and when to utilize this interventi

12 Yet, there is limited understanding of how and where stimulus information is l

13 ovide complementary results that support the understanding of how and why a model works.

14 pite a growing number of investigations, our understanding of how and why this recovery occurs is ver

15 Having a better understanding of how anthropogenic changes affect delta

16 A better understanding of how antibiotic exposure impacts the evo

17 urgently need to gain a better quantitative understanding of how antibiotics act, which in turn woul

18 future areas of study needed to advance our understanding of how ApoE influences neurodegeneration.

19 Thus, to obtain a deeper understanding of how auditory stimuli are processed, and

20 A better understanding of how B. burgdorferi transmigrates throug

21 gst P-type pumps and this study furthers our understanding of how bacteria control potassium homeosta

22 A better mechanistic understanding of how bacteria invade, survive within, an

23 enabled biochemical studies that deepen our understanding of how bacterial cell wall enzymes coopera

24 Mouse genetics have increased our understanding of how barrels are constructed and reveale

25 ability for many species is needed, as is an understanding of how barriers to dispersal may impact vu

26 Our findings provide a new, mechanistic understanding of how behavioural properties can modulate

27 ances in microbiome science require a better understanding of how beneficial microbes adapt to hosts.

28 on how these methods have been changing our understanding of how brain supports mind.

29 d frontotemporal dementia (FTD), yet a clear understanding of how C9 fits into the broader context of

30 This study changes the foundational understanding of how cancer cells hijack the bone marrow

31 Yet our understanding of how cancer cells sense and convert mech

32 A comprehensive understanding of how cancer mutations rewire immune sign

33 function of the cerebellum and advances our understanding of how Caspr2 dysfunction might lead to sp

34 Our results advance our understanding of how cell-specific neurobiological gradi

35 of cellular iron has produced a more nuanced understanding of how cells utilize this crucial nutrient

36 This study will aid not only in our understanding of how cellular networks form but highligh

37 t centers, underscoring the need for greater understanding of how centers make decisions about organs

38 echanism of oligomerization will further our understanding of how chaperones maintain the proteome.

39 osomes, potentially bridging the gaps in our understanding of how chromatin works within living cells

40 inical links are well established, molecular understanding of how chronic inflammation leads to the d

41 findings suggest that a deeper systems-level understanding of how ciliary proteins function together

42 An increased understanding of how climate disruption might link to de

43 her patterns and phenology; however, we lack understanding of how climate drives phenological change

44 in materials science requires a fundamental understanding of how close packing of molecules can affe

45 mary, our analyses provide insights into the understanding of how complex morphological traits are sh

46 istorical hypotheses and discuss the present understanding of how corals evolved and how their skelet

47 The understanding of how cross-reactive responses develop is

48 ween different delivery modes can add to our understanding of how CS contributes to disease patterns

49 This study advanced our understanding of how cutaneous plantar sensation can be

50 in psychostimulant-shaped behaviors, and new understanding of how D1-medium spiny neurons encode the

51 ys clear, at least in part because of a poor understanding of how different feeding behaviors impact

52 However, a detailed mechanistic understanding of how different microbial communities are

53 oaches provide powerful tools to further our understanding of how different opioids affect signaling

54 ntegrating this information with an emerging understanding of how different tumor mutations influence

55 However, our understanding of how different vaccine types elicit dura

56 An understanding of how dioxygen is delivered to, and binds

57 which remain poorly characterized, impeding understanding of how disease-associated mutations cause

58 of microbial diversity and function, but our understanding of how dispersal influences responses to n

59 an important building block for the broader understanding of how distracters are suppressed, and of

60 y, researchers and managers require a better understanding of how diverse species respond to extreme

61 mechanical properties of DNA has limited our understanding of how DNA mechanics influence chromatin t

62 is work lays the foundation for a structural understanding of how DNA targeting by TniQ-Cascade leads

63 Ultimately, a better understanding of how donor intrinsic immunity influences

64 nflammatory skin conditions relies on a deep understanding of how drugs and tissue behave and interac

65 isolation and when grown together helps our understanding of how ecological communities more general

66 Developing a thorough understanding of how ectotherm physiology adapts to diff

67 By contrast, an understanding of how effectors manipulate nonimmunity pa

68 These discoveries expand our understanding of how eggshell colour diversity is achiev

69 A mechanistic understanding of how eIF6 modulates translation in respo

70 A better understanding of how ELS interacts with sex to alter tra

71 diversity is critical to a more mechanistic understanding of how EM fungi mediate forest soil biogeo

72 Yet, we have limited understanding of how EMC enables insertion and integrity

73 A better understanding of how enhancers work will improve the int

74 This deeper understanding of how enzymatic changes in chromatin stru

75 This study advances our understanding of how epigenetic landscapes shape cancer

76 scent erythrocytes, which alters our current understanding of how erythrocyte degradation is regulate

77 e example is the progressively sophisticated understanding of how extinction underlies the exposure t

78 However, there is a limited understanding of how fatigue impacts effort-based decisi

79 However, our understanding of how fine-grained changes in microstruct

80 diate below-ground resource acquisition, yet understanding of how fine-root functional traits vary al

81 blow flies will allow a refined evolutionary understanding of how flies with a typical X/Y heterogame

82 ome fluorinated motifs and are enhancing our understanding of how fluorine should be deployed.

83 h the progress and the limits of our current understanding of how force generation can be controlled

84 recognition of its functional relevance, our understanding of how FWU occurs and which foliar surface

85 Our understanding of how GAS genes contribute to interaction

86 ects from GC, thereby necessitating a better understanding of how GCs modulate the immune response.

87 pment and immune responses provide a nuanced understanding of how GCs shape immunity.

88 the magnitude of genetic effects and little understanding of how genetic factors might influence car

89 There is a limited understanding of how genetic loci associated with glycem

90 of a scarcity of functional studies and poor understanding of how genetic or gene expression landscap

91 nscriptional mechanisms can help improve our understanding of how genetic variants exert their effect

92 s in genomics have dramatically advanced our understanding of how genetics contributes to host resist

93 The past decade has increased our understanding of how genome topology controls RAG endonu

94 r hierarchical control of Gq and changes our understanding of how Gi-GPCRs trigger [Ca(2+)](i) via PL

95 Nevertheless, our understanding of how gut bacteria modulate the immune sy

96 Our studies provide a deeper understanding of how gut microbial metabolites affect ho

97 nd remove H2Bub1, we have only an incomplete understanding of how H2Bub1 is regulated.

98 differentiation to gain a more comprehensive understanding of how habitat loss and fragmentation infl

99 able respiratory model systems has precluded understanding of how herpesvirus virions overcome the ab

100 This model offers great promise for basic understanding of how HIV-1 infection alters the CNS comp

101 These studies provide a better understanding of how host-guest binding in flexible rece

102 plasticity of cells during development, the understanding of how human trisomy 21 effects Down syndr

103 We summarize recent advances in our understanding of how IL-22 regulates homeostasis and hos

104 ically informed conservation and advance our understanding of how imperiled species might be rescued

105 ree-living communities, but we still lack an understanding of how important interspecific association

106 sed organelles and therapeutics, however, an understanding of how individual molecules contribute to

107 Achieving this goal will require a detailed understanding of how infection history impacts humoral r

108 However, a comprehensive understanding of how infections with pathogens that exhi

109 re have been significant advancements in our understanding of how inflammation contributes to the pat

110 Our study provides new understanding of how inflammation may alter stem cell-ex

111 Such discrepancy calls for a better understanding of how information spreads from person to

112 In this Review, we summarize our current understanding of how interactions between RGCs and their

113 puts of the CeA and pave the way to a better understanding of how internal, external, and experience

114 Mechanistic understanding of how ionizing radiation induces type I i

115 to get direct access to the molecular-level understanding of how ions change the structure and dynam

116 metastasis , but we still have a superficial understanding of how it affects cellular processes durin

117 factor for multiple sclerosis (MS), but our understanding of how it contributes to MS is limited.

118 er and neurodegeneration, and so an in-depth understanding of how it is regulated has implications fo

119 cosystem experiencing rapid warming, yet our understanding of how its diverse assemblage of endemic s

120 This requires an understanding of how kinetic information is represented

121 d in pollinator declines worldwide, a better understanding of how land use change impacts species int

122 A broader understanding of how landscape resistance influences cli

123 source availability, and provide an improved understanding of how landscape-level features can impact

124 Recent developments in the understanding of how lanthanides are selectively acquire

125 ghts both the progress and the limits of our understanding of how (lipo)polysaccharides, (glyco)lipid

126 This study advances our understanding of how lipogenesis is regulated downstream

127 However, the continued limited understanding of how lithium modulates affective behavio

128 been studied intensively; however, a unified understanding of how localisation and protein activity f

129 ch using this model continues to advance our understanding of how macrophages, and specific pathways

130 operando neutron measurements can allow for understanding of how materials behave throughout operati

131 nd that should be a goal for a comprehensive understanding of how mechanical load influences cell sig

132 ach to neuroscience can greatly increase our understanding of how mechanisms map onto behaviour.

133 of biocompatible electronics and enhance our understanding of how membrane potential regulates organe

134 his review summarizes recent advances in our understanding of how metal sensor proteins respond to in

135 In this study, we contribute an atomic-level understanding of how methadone exerts its unique functio

136 This study establishes a better understanding of how Mg(2+)-ion interactions contribute

137 However, our understanding of how microbial communities are structure

138 However, a predictive understanding of how microbial communities respond to ch

139 These results extend understanding of how microbial systems can influence bio

140 we review recent advances in our mechanistic understanding of how microbiota-derived metabolites orch

141 crobial ecology and dramatically improve our understanding of how microorganisms function in their na

142 on for the assembled complex has hindered an understanding of how Microprocessor recognizes primary m

143 This study increases our understanding of how mitochondria modulate neuronal home

144 Here, we review recent progress in our understanding of how mitochondria serve as intracellular

145 otors allows us to challenge our fundamental understanding of how molecular motors transduce energy.

146 dies supporting this function, a mechanistic understanding of how Msp1 extracts its substrates is sti

147 due to numerous human-caused stressors, our understanding of how multiple stressors influence BEF re

148 These data provide a greater understanding of how Myc transcriptional activity is det

149 polydisperse fiber lengths and an incomplete understanding of how nanofiber length affects biological

150 ental variability due to climate change, our understanding of how natural populations persist and res

151 lable for anthropogenic-related threats, our understanding of how naturally occurring extreme events

152 Herein, we review advances in the understanding of how naturally occurring variation in cl

153 rs on spinal network output and advances our understanding of how neuromodulators regulate neural net

154 Here, we discuss our current understanding of how neuronal and glial development affe

155 There is substantial understanding of how neuronal phase locking of afferent

156 Despite impressive progress, our understanding of how neurons form the nervous system and

157 esolution analyses fundamentally advance our understanding of how niche factors shape SC biology and

158 e current findings significantly improve our understanding of how nicotine changes corticostriatal ci

159 there have been significant advances in our understanding of how nitrogenase orchestrates electron t

160 adsorption and catalysis, but a mechanistic understanding of how nonaqueous solvents influence catal

161 These studies have greatly advanced our understanding of how noxious mechanical stimuli are dete

162 Such work will significantly advance our understanding of how opioids cause persistent changes to

163 of the IPR in C. elegans, which adds to our understanding of how organisms cope with proteotoxic str

164 metry for grasping in the PMC and expand our understanding of how our brain integrates visual and mot

165 rrently, however, we lack a full mechanistic understanding of how oxygen deficiency affects organic c

166 ries and their adaptive tolerances, a fuller understanding of how past climatic and ecological change

167 nally, we discuss recent developments in our understanding of how pathogens can evade ETI to overcome

168 been made in plant pathology, broadening our understanding of how pathogens colonize their hosts.

169 iew, we highlight recent developments in our understanding of how pathogens invade and survive within

170 This review discusses our current understanding of how PDA originates.

171 These findings contribute to our understanding of how people perceive and make inferences

172 In this Review we present our current understanding of how peptidoglycan synthases are regulat

173 A circuit understanding of how perception links to response requir

174 Second, we need a better mechanistic understanding of how physical conditions in streams driv

175 t research by Fan and colleagues deepens our understanding of how physical stress alters the immune s

176 major drivers is needed to achieve a better understanding of how plants adapt to different environme

177 Here, we review current understanding of how plants shape the rhizosphere and th

178 These results deepen our understanding of how prior knowledge informs perception.

179 Thus, a comprehensive understanding of how processing delay affects major endp

180 ies found in the tropics, yet we have little understanding of how projected changes in climate are li

181 Our understanding of how projected climatic warming will inf

182 bly slow without metal cofactors, a detailed understanding of how protein structure can influence cat

183 network are generally well established, our understanding of how protein-folding problems are identi

184 These results illuminate our understanding of how protist diversity, biogeographical

185 Our study not only deepened our understanding of how ratio-sensing is achieved in yeast

186 A better understanding of how recipient antiviral responses lead

187 erous evolutionary phenomena, we have a poor understanding of how recombination rate itself varies an

188 This chicken skin paradigm advances our understanding of how regulation of big gene clusters can

189 These results extend our understanding of how resident AMs participate in host de

190 h on the molecular mechanisms of resistance, understanding of how resistance evolves remains limited.

191 with important implications for a predictive understanding of how RNA is recognized and for RNA-targe

192 eostasis through CLASP, and they advance our understanding of how roots modulate their growth accordi

193 Our understanding of how rotavirus (RV) subverts host innate

194 the beta-lactam antibiotics through a better understanding of how S. aureus protects the enzyme targe

195 pulation genetic approaches is improving our understanding of how selection acts on key floral traits

196 However, our understanding of how self-reactive B cells escape self-t

197 A better understanding of how senescence contributes to joint dys

198 gether, a more comprehensive and mechanistic understanding of how sex differences in dopamine functio

199 This study provides a mechanistic understanding of how Six1 cooperates with distinct cofac

200 EWAS and have important implications for our understanding of how smoking affects immune-cell subtype

201 This will increase our understanding of how social isolation and loneliness rel

202 cal C protection mechanisms, challenging our understanding of how soil C may respond to climate-media

203 of soil organic matter (SOM) is vital to our understanding of how soils form, evolve and respond to e

204 approaches have provided insights toward our understanding of how sophisticated cellular machineries

205 ues, and live-cell imaging have advanced our understanding of how specific myosins function at indivi

206 Neuroimaging has radically improved our understanding of how speech and language abilities map t

207 However, we have little understanding of how stomatopods perceive these signals

208 nd veterinarians is warranted to further our understanding of how stones form and to consider possibl

209 mporary earthquake hazard models hinge on an understanding of how strain is distributed in the crust

210 interaction types is imperative for a better understanding of how stressors affect populations.

211 A precise understanding of how such events contribute to intratumo

212 Our results contribute to a better understanding of how sulfide metabolism is integrated in

213 Here, we review the current understanding of how systemic factors mediate brain agei

214 These data aid our understanding of how systemic inflammation may augment t

215 hat should always be enveloped by a thorough understanding of how systems and the social exposome sha

216 Here, we review current understanding of how Tfh cells contribute to the selecti

217 g the results of this study with our current understanding of how TGF-beta1 regulates microglia polar

218 This complexity has limited understanding of how the "don't eat me" signal is transd

219 An imprecise understanding of how the amygdala fits into the larger n

220 Our findings inform the understanding of how the auditory system encodes sociall

221 Here, we examine the current understanding of how the axial tissues that are formed d

222 ctive HIV-1 antibodies will require a better understanding of how the biophysical properties of the e

223 findings present an important advance in our understanding of how the brain might use Bayesian infere

224 europharmacology has not yet achieved a full understanding of how the brain transitions between state

225 Such evidence however complicates our understanding of how the chicken was domesticated becaus

226 Our understanding of how the complexity of the wheat genome

227 ponses to perceptual figures, we have a poor understanding of how the early visual system contributes

228 However, there is a gap in our understanding of how the enzyme assembles into a functio

229 . microporus should contribute to the better understanding of how the fungus is able to facilitate wo

230 This Review examines recent progress in our understanding of how the future looks for forests growin

231 eural activity are an important tool for the understanding of how the healthy brain can maintain stab

232 However, our understanding of how the host cell environment influence

233 These findings contribute to understanding of how the identity of the mismatch affect

234 An understanding of how the IDP nature of p27 underpins its

235 A detailed understanding of how the internal clock regulates cognit

236 There is a major gap in our understanding of how the intestinal immune and nervous s

237 ovations in healthcare delivery and a deeper understanding of how the liver and other vital organs su

238 behaviour, and can be used to gain a better understanding of how the many choice phenomena and key t

239 OFs, COFs, etc.) is presently limited by our understanding of how the molecular constituents assemble

240 as the potential to be transformative to our understanding of how the most energetic particles in the

241 r kills, but we currently lack a mechanistic understanding of how the multiple facets of climate inte

242 Unfortunately, we still lack clear understanding of how the pathogen responds to host and e

243 review discusses recent developments in our understanding of how the physiology of high-latitude mar

244 Yet, we still lack understanding of how the response to inductive signals i

245 For example, an understanding of how the sequence features of these regi

246 CE STATEMENT Findings here contribute to our understanding of how the serotonin system underlies an i

247 le are rare, and consequently we have a poor understanding of how the taxonomic and functional microb

248 inations is limited, in part by insufficient understanding of how the transcriptional response of two

249 Remaining gaps in knowledge include an understanding of how the TTFL proteins behave individual

250 Here we review how these structures aid our understanding of how the various mutations in the genes

251 Our current understanding of how the visual brain develops is based

252 their physiological function and our current understanding of how their dysregulation may contribute

253 lication has been frustrated by an imprecise understanding of how their signals are transduced into i

254 an by soil structure and then review current understanding of how these biological agents impact soil

255 ecently appeared that allow advancing in the understanding of how these compounds are produced.

256 A better understanding of how these different human capabilities

257 However, our understanding of how these disturbances interact to affe

258 isruption of this activity will increase our understanding of how these early circuits mature and may

259 However, we have a poor understanding of how these enzymes are regulated in vivo

260 e roles in cells, there are many gaps in our understanding of how these enzymes are regulated.

261 However, our understanding of how these events affect population dyna

262 Ultimately, a deeper understanding of how these factors interact with and aff

263 These findings deepen our understanding of how these fundamental biological proces

264 llergen-specific immunotherapy outcomes, but understanding of how these integrate to maintain immunol

265 kpropagating action potentials, shifting our understanding of how these neurons process information,

266 Consequently, a detailed understanding of how these parasites harness host pathwa

267 and photic input pathways, but a mechanistic understanding of how these pathways collaborate in anima

268 A more thorough understanding of how these pharmacological agents intera

269 tical for activation of RAF kinases, yet our understanding of how these proteins interact on the memb

270 emically modified forms, but we lack a clear understanding of how they alter interactions with microb

271 ain parts of the world, yet there is limited understanding of how they are consumed, particularly the

272 nic pathogen-derived epitopes and a detailed understanding of how they are recognized by TCRs is esse

273 term weight-loss strategies, coupled with an understanding of how they interface with human physiolog

274 select adsorption properties without a clear understanding of how they perform in real-world VSA proc

275 d comparative analysis to advance scientific understanding of how this core physiological system has

276 s viral infections, necessitating a detailed understanding of how this diverse family of receptors fu

277 The current understanding of how this is achieved is through recepto

278 A comparative understanding of how this limited resource is partitione

279 NPQ limits photosynthesis and linking to our understanding of how this might take place on a molecula

280 s dysregulated in the brain will further our understanding of how this pathway contributes to the dev

281 issues and organs remains limited, as is our understanding of how this process could be harnessed for

282 tment options and for the basic biomolecular understanding of how this process intersects with RNA me

283 The understanding of how this supply is regulated in the mic

284 These lines of research aim to extend our understanding of how timing arises from and contributes

285 itical physiological role, a molecular-level understanding of how TJ assembly sets the permeability o

286 isease surveillance and a broader gap in our understanding of how to best use detailed spatial data t

287 self-generated states, we lack both a clear understanding of how to classify the specific states, an

288 echnological platforms will lead to a better understanding of how to harness metagenomes.

289 e array of physiological processes, a deeper understanding of how to modulate mitophagy could provide

290 owledge from these regions contributes to an understanding of how to obtain a sustainable ocean.

291 These results advance our understanding of how to use Env trimers in multivalent v

292 bolomic tools for conifers have improved our understanding of how trees sense and respond to changes

293 pplication, but limitations exist in current understanding of how tumors exert local effects on resti

294 However, an understanding of how un-ionized ammonia transfers is vit

295 Our results establish a mechanistic understanding of how vamorolone reduces side effects, gu

296 le alpha2delta isoforms has obscured a clear understanding of how various alpha2delta proteins contro

297 Here, we review recent advances in our understanding of how various components of the fetal imm

298 l responses during latency establishment, an understanding of how viral gene products function in spe

299 ory elements that p53 engages; reviewing our understanding of how, where, and when p53 binds to DNA a

300 Although we have a well-developed understanding of how wind and precipitation events can a