ライフサイエンスコーパス: unequivocal

1 resistance exercise in aging populations are unequivocal.

2 e data on L2-E and L3-E interactions are not unequivocal.

3 the initial stage of Alzheimer's disease is unequivocal.

4 results suggest that the association is not unequivocal.

5 Although the evidence is not yet unequivocal, a growing body of evidence supports the exi

6 link between mutant TP53 and human cancer is unequivocal, a significant knowledge gap exists in clini

7 ng the risk of misdiagnosis and the need for unequivocal amyloid typing.

8 accuracy and interpretability, resulting in unequivocal analyses and assignments of experimental spe

9 The use of qualifier ions supports unequivocal analyte verification.

10 tent and DNA replication, this method allows unequivocal and direct assignment of cell cycle distribu

11 We present unequivocal and model-free experimental proof for the pr

12 PFC nanoparticles provide an unequivocal and unique signature for stem/progenitor cel

13 7.4 years), except for three, experienced an unequivocal angioedema of the lips as a positive reactio

14 both animals and humans have not provided an unequivocal answer.

15 resulting OVA-VIB conjugate, a selective and unequivocal antigenic response to the VIB hapten was obs

16 erformed on 20 biopsies (normal kidney, n=4; unequivocal AR, n=5; features of APN, n=11).

17 ad MRI-evident sacroiliitis, and 6 (12%) had unequivocal AS according to the modified New York criter

18 ine 46 in models of disease should allow the unequivocal assessment of whether GAPDH aggregation infl

19 -coated microspheres is introduced, allowing unequivocal assignment of docking and membrane fusion.

20 during synthesis was designed to facilitate unequivocal assignment of isobaric residues by MALDI-TOF

21 LYP/6-31G* level with COSMO model, permitted unequivocal assignment of its 2R,3S absolute configurati

22 al cross-repressive interactions that ensure unequivocal assignment of neural progenitor identity to

23 acy provided by FTICR MS allow for rapid and unequivocal assignment of relevant peptides and provide

24 Their structures allow unequivocal assignment of the absolute configuration for

25 etric assessment of this sample supports its unequivocal assignment to H. sapiens.

26 the use of orthogonal methods is needed for unequivocal assignment.

27 l explosion in new knowledge with reports of unequivocal association to relevant genes appearing almo

28 ation of symptoms in detected cases shows an unequivocal association with detection effort.

29 ra of selectively (13)C-labeled protein show unequivocal attenuation of cross-peaks after membrane bi

30 nt asymmetric total synthesis to provide the unequivocal authentic materials.

31 These fossils represent the only unequivocal basal theropod embryos found to date.

32 or vapor deposition on ice grains, exhibited unequivocal bathochromic shifts of 10-15 nm of the absor

33 y/mortality trial) studies together show the unequivocal benefit for CRT therapy and CRT therapy with

34 controversial because evidence demonstrating unequivocal benefit is lacking.

35 on the prevent/delay end points that reflect unequivocal benefit to a patient: prolongation of life o

36 g the development of cardiac hypertrophy has unequivocal benefits on cardiac function and energetics.

37 Results: In total, 3,473 unequivocal bone lesions were identified in 102 evaluate

38 can Association for Cancer Research makes an unequivocal call to all who are concerned about public h

39 haemoglobin, but no trial results have shown unequivocal cardiovascular risk reduction with glucose l

40 r discrimination between melanoma and benign unequivocal cases as well as between different atypia su

41 or switch in these cells precisely marked an unequivocal change in EMT status, defining the pre-EMT a

42 direduced states of the two isomers allowing unequivocal characterization of the reduced species by U

43 Here we report the first unequivocal chemical evidence, based on the delta(13)C a

44 The lack of a precisely-dated, unequivocal climate proxy from northern China, where pre

45 ials in human subjects have not demonstrated unequivocal clinical benefits.

46 than 3 years, Gleason score progression, or unequivocal clinical progression.

47 e results suggest that job control is not an unequivocal concept in relation to mortality; decision a

48 d better-designed studies are needed to draw unequivocal conclusions about the effect of statins on c

49 ate sensitivity and specificity in providing unequivocal confirmation of rhEPO and DPO in equine plas

50 tems and in animal models of oxidant injury, unequivocal confirmation of their beneficial effects in

51 Particularly, there is unequivocal consensus that endogenous retrotransposition

52 In this report, we establish unequivocal correlations between patient clinical phenot

53 ge differentiation and represents the oldest unequivocal crown-group mandibulate known from complete

54 ng sucrose, but human studies do not provide unequivocal data of their cariogenicity.

55 However, unequivocal data required to prove that interchromosomal

56 The only unequivocal deficiency outcome is a bleeding syndrome ca

57 may take damage to both sides to produce an unequivocal deficit of central semantic memory.

58 this notion may be considered intuitive, its unequivocal demonstration is still lacking.

59 However, an unequivocal demonstration of "protein-only" infection by

60 These results represent the first unequivocal demonstration of a role for Ldb1 in erythrop

61 search design was not capable of offering an unequivocal demonstration of inequity aversion.

62 Fitting of a thermodynamic model allows unequivocal demonstration of looping and comparison of t

63 some 25 million years and provides the first unequivocal demonstration of ostracods in the Ordovician

64 cal application of this principle depends on unequivocal demonstration of safety in primate models fo

65 ft composition and properties have prevented unequivocal demonstration of their functional relevance.

66 Our work is the first unequivocal demonstration that homologous recombination

67 These studies also represent the first unequivocal demonstration that OxDC activity is uniquely

68 y Universe, the HeH(+) ion has so far eluded unequivocal detection in interstellar space.

69 ramide signal amplification (TSA) to achieve unequivocal detection of cell bodies of GABAergic neuron

70 n situ through-container analysis; achieving unequivocal detection of multiple chemical markers known

71 The V5-HA tag allows unequivocal detection of RanBP9 both by IHC and WB.

72 The method enabled the unequivocal detection of up to 1% of each adulterant, al

73 SY, and COSY data obtained have also allowed unequivocal determination of the orientation of the PBD

74 levels, has clinical utility in providing an unequivocal diagnosis in patients and in identifying aff

75 ia motion contrast and may contribute to the unequivocal diagnosis of CNV in this population.

76 Unequivocal discrimination between neutral variants and

77 fferent compared to conventional milk but an unequivocal discrimination was not possible either in su

78 ocalization of nanoparticles, does not allow unequivocal distinction between cell surface-bound and i

79 ehensive LC-MS/MS based approach that allows unequivocal distinction of these two lipid subclasses ba

80 eless diagnosed as affected by LQTS based on unequivocal ECG abnormalities (QTc, 472+/-33 ms).

81 to-noise ratio for nickel porphyrins enables unequivocal elemental composition assignment confirmed b

82 He presented specific, unequivocal emotion recognition impairments.

83 Unequivocal eradication of donor leukocyte microchimeris

84 Using En(a-) cells to get an unequivocal estimate of the use of glycophorin A (GPA) a

85 remain as to their specific role(s), and no unequivocal evidence exists showing that these compounds

86 sights into the nanorod growth mechanism and unequivocal evidence for a concerted growth-organization

87 riginate in the paternal lineage and provide unequivocal evidence for an increase in mutation with pa

88 We provide unequivocal evidence for EndMT at the invasive front of

89 and nonavian theropod species have provided unequivocal evidence for feathers and/or downlike integu

90 700 kyr ago) and thus represent the earliest unequivocal evidence for human presence north of the Alp

91 dation and antioxidant capacity, we obtained unequivocal evidence for oxidative stress in this disord

92 gitudinal ridges should not be considered as unequivocal evidence for presence of ice, rather as inev

93 trials, but it has been difficult to obtain unequivocal evidence for robust clinical benefit.

94 These findings represent unequivocal evidence for saccadic suppression in human L

95 P, [CD(3)]-dThd and [CD(3),6D]-dThd, we find unequivocal evidence for T(5OH). formation and its conve

96 manipulation of the cell cycle and generated unequivocal evidence for the continuous accumulation of

97 Moreover, lessons from PID have provided unequivocal evidence for the essential role of regulator

98 We provide unequivocal evidence for the formation of the ring-proto

99 cterization of JAM-C SC KO mice has provided unequivocal evidence for the involvement of SC JAM-C in

100 Using Bayesian model comparison, we found unequivocal evidence for the modulation of extrinsic (be

101 w fluorescence and NMR experiments that give unequivocal evidence for the presence of a ternary DNA-N

102 The center of the controversy is the lack of unequivocal evidence in favor of myocardial regeneration

103 However, none of these therapies has shown unequivocal evidence in improving patient clinical statu

104 e the risk of mammary tumor development, but unequivocal evidence is still lacking.

105 Moreover, there is now unequivocal evidence linking dysbiosis to cancer develop

106 These findings provide unequivocal evidence of a functional interaction between

107 fants, research during recent years provided unequivocal evidence of active BAT in human adults.

108 nd binding, a decrease in k(obs) with [L] is unequivocal evidence of conformational selection, but an

109 , the modified zonal elution method provides unequivocal evidence of direct interaction between RARga

110 y to synthesize LTB(4) and cysLTs, providing unequivocal evidence of efficient transcellular biosynth

111 cause none of its preserved anatomy provides unequivocal evidence of homology, without which comparat

112 lovis complex is considered to be the oldest unequivocal evidence of humans in the Americas, dating b

113 n, but an increase in k(obs) with [L] is not unequivocal evidence of induced fit.

114 Two participants were excluded because of unequivocal evidence of liver metastases at baseline who

115 Despite unequivocal evidence of ocean acidification (OA) via ope

116 ese reports shows that, so far, none provide unequivocal evidence of pre-Cretaceous angiosperms.

117 ollution and cardiovascular disease in 2010, unequivocal evidence of the causal role of fine particul

118 However, unequivocal evidence supporting the ferrireductase activ

119 This result provided unequivocal evidence supporting the notion that the 8-MO

120 This report provides the first unequivocal evidence that a bacterium is capable of cons

121 Most importantly, we find unequivocal evidence that ants are the sister group to b

122 finity (IC(50) in microgram ranges), provide unequivocal evidence that AuNP-BBN constructs are GRP-re

123 1/2-catalyzed cleavage reaction, and provide unequivocal evidence that CEs are retained within the CE

124 l trials began in 1989 and by 2002 there was unequivocal evidence that children with severe combined

125 Our data provide unequivocal evidence that CRACM1 multimers form the Ca(2

126 ated mutants and transgenic lines to provide unequivocal evidence that cytokinins have a key role in

127 y virus in complex with D1D2-IgP, we present unequivocal evidence that D1D2-IgP can cross-link surfac

128 TERPRETATION: For the first time, we provide unequivocal evidence that fibrin(ogen) is extensively de

129 Taken together, these results provide unequivocal evidence that menadione is a catabolic produ

130 our knowledge, this study provides the first unequivocal evidence that naive CD4(+) T cells can be ac

131 Unequivocal evidence that only the trimer containing two

132 We report unequivocal evidence that Pacific bluefin tuna, Thunnus

133 We provide unequivocal evidence that PD-1 is highly expressed (PD-1

134 of resource concentration, provide the first unequivocal evidence that population size is one of the

135 ulated Psp proteins has allowed us to obtain unequivocal evidence that PspA is not required for secre

136 XANES, EXAFS, and EQCM collectively provides unequivocal evidence that reversible oxidative NO(3) (-)

137 stent with sperm competition theory, provide unequivocal evidence that sperm competition risk drives

138 However, as yet, few studies provided unequivocal evidence that the cerebellum is involved in

139 These results provide the first unequivocal evidence that the substrate specificity of F

140 transmission electron microscopy to provide unequivocal evidence that under near-physiological condi

141 Despite decades of unequivocal evidence that waist circumference provides b

142 Thus, our findings provide the first unequivocal evidence to explain the tolerability of mema

143 within the lumen of Wza, providing the first unequivocal evidence to our knowledge that nascent capsu

144 Collectively, these results provide unequivocal evidence toward alternative promoter switch-

145 However, unequivocal evidence was only provided once mouse models

146 Unequivocal evidence, from mass spectral studies, indica

147 This also provides a rare unequivocal example of conditional reciprocity averting

148 ) complex) and H(2) , the latter offering an unequivocal example of heterolytic E-H bond cleavage acr

149 Moreover, this is the first unequivocal example of successful engraftment of endocri

150 The youngest unequivocal examples occur in the middle Cambrian Marjum

151 ior with high fidelity, the stark absence of unequivocal examples of cumulative culture in nonhumans

152 ows that this conjecture is not supported by unequivocal experimental evidence.

153 Here we present unequivocal experimental proof that microscale cofactor-

154 Despite these unequivocal findings in rodents, similar changes cannot

155 Here, we report an unequivocal fossil hagfish from the early Late Cretaceou

156 onary history of hagfish in general, because unequivocal fossil members of the group are unknown.

157 te Triassic, are considerably older than the unequivocal fossil record of flowering plants or than th

158 Only 5 states offer unequivocal funding to schools for purchasing AEDs.

159 These findings provide the first unequivocal genetic evidence for an essential physiologi

160 y, the spectrum of driver mutations provided unequivocal genomic evidence for a direct mutagenic role

161 atment with insulin-like growth factor I for unequivocal growth hormone insensitivity improves but do

162 T findings that occupy the gray area between unequivocal health and definite disease, with a particul

163 so examined and their levels do not indicate unequivocal higher pathway activity in tumors with mutat

164 Cellular identification of GDNF by unequivocal histochemical methods demonstrated that in n

165 ith the highly attenuated mutants, there was unequivocal HMPV replication at each anatomical site in

166 basic morphological information allowed the unequivocal identification at the species level of 90% o

167 es unspecific isotopic dilution ICP-MS, with unequivocal identification by quadrupole-time-of-flight

168 Herein we demonstrate for the first time the unequivocal identification of ABA within a monocytic T h

169 ) at sub-atomic resolution and allows for an unequivocal identification of all atoms involved in the

170 ntation pattern of general applicability for unequivocal identification of covalently attached compou

171 lentiviral transduction system to allow the unequivocal identification of live murine corticotrophs

172 eted metabolomics strategy with pipeline for unequivocal identification of metabolites using the MSML

173 Recent advances have led to the unequivocal identification of microorganisms responsible

174 ne residues presenting a major challenge for unequivocal identification of specific phosphorylation s

175 ver increasing, there is a need for fast and unequivocal identification of suspect organisms to suppl

176 s full scan and full scan MS/MS data for the unequivocal identification of target analytes.

177 e are subject to weak background noise only, unequivocal identification of the hidden node can be ach

178 understanding of these processes requires a unequivocal identification of the N reserves in microalg

179 irradiation with lambda = 340 nm led to the unequivocal identification of the nitrile ylide anti-4,

180 characteristic spatial mosaics and afforded unequivocal identification of the parasol cells among di

181 ased on a hierarchical sampling strategy and unequivocal identification of the region of interest, se

182 arge populations of lysenin channels allowed unequivocal identification of the unmodified analyte by

183 itol pyrophosphates in their seed, providing unequivocal identification of their presence in plant ti

184 Unequivocal identification of these phases using X-ray d

185 firmed that the use of DNA barcoding allowed unequivocal identification of this new pest from Ghana b

186 This enabled unequivocal identification of tumor cells emerging from

187 labeling in cell culture method enables the unequivocal identification of tyrosine kinase substrates

188 mozygous presence of the deletion allows the unequivocal identification of Vel-negative blood donors.

189 MS/MS data and requires using MS/MS data for unequivocal identification.

190 the lack of specific markers allowing their unequivocal identification.

191 m their native counterparts leading to their unequivocal identification.

192 onal tandem mass spectrometry cannot provide unequivocal identification.

193 Eight participants (5.2%) presented unequivocal IgE-mediated reactions to peanut upon introd

194 al cells alone representing the only site of unequivocal IL-6 receptor expression.

195 Design, Setting, and Participants: Unequivocal in situ melanoma without associated nevi or

196 secutive cases (33%) of previously diagnosed unequivocal in situ melanoma.

197 (C(ant)) and a decrease in carbonate that is unequivocal in the upper and mid-layers (0-2,500 m depth

198 ough correlated equivalence points providing unequivocal, in situ evidence that identifies how SOFC p

199 ame promoter as the shRNA, thus providing an unequivocal indicator, not only to the cells that expres

200 hes (SNAPS) that exploits the modularity and unequivocal input/response of Notch proteolysis to scree

201 ls analysed provide evidence for limited but unequivocal interaction between water and the volcanic r

202 e more complex than is often assumed, and an unequivocal interpretation of fMRIa results can be achie

203 atus was often different between metastases, unequivocal intra-tumor heterogeneity was not found in i

204 of knock-in mice through the conditional and unequivocal labeling of insulin fused to the SNAP tag.

205 The new evidence presented here for unequivocal lethal violence on a large scale is put into

206 he northwest Indian Ocean, where, despite an unequivocal link between an onshore flood basalt provinc

207 edge structure investigations revealed in an unequivocal manner the formation of up to about 60% of C

208 , the collective mass in graphene has defied unequivocal measurement.

209 SILV, GDF15, and L1CAM normalized to TYR in unequivocal melanoma versus benign nevi resulted in an a

210 imary tumors or metastases or radiologically unequivocal metastatic lesions of histologically proven

211 n receptor complex (MCRC) in this process is unequivocal, modalities independent of this complex are

212 agenesis data allowed the construction of an unequivocal model of dimeric H(C) in solution.

213 uced DNA double-strand breaks is profuse and unequivocal; moreover, it is clear that the RAG complex

214 a bilaterally symmetrical body, there are no unequivocal morphological characters to support placemen

215 Consequently, there is an unequivocal need for more active and specialised metrics

216 To date, unequivocal neuroanatomical features have been demonstra

217 en adequately studied because of the lack of unequivocal nomenclature.

218 ations of NO donors also stimulate rapid and unequivocal nuclear retention of p53 but apparently do n

219 derwent an investigational biopsy all had an unequivocal or probable malignant intraocular tumor of a

220 periodontitis-chronic and aggressive-lack an unequivocal, pathobiology-based foundation.

221 or lower stages, only the IRSS considers all unequivocal pathological prognostic factors.

222 derperformance or partial stent obstruction, unequivocal patterns of focal outflow enhancement by TMB

223 However, in this study a straightforward unequivocal peak assignment was achieved for all unknown

224 only known impact structure on Earth with an unequivocal peak ring, but it is buried and only accessi

225 corded on activation of the M-cell, allowing unequivocal physiological identification of the M-cell a

226 es has produced differences in opinion, from unequivocal positive evidence to no evidence at all for

227 ence of one of the strongest, nonlinear, and unequivocal postindustrial increases in intrinsic water

228 Our results demonstrate the unequivocal presence of eumelanin in T. imperator headcr

229 Few if any studies have demonstrated the unequivocal presence of intracellular ABA.

230 Besides age, unequivocal presence of spinal cord lesions and being ma

231 ients who underwent a prognostic FNAB had an unequivocal primary posterior uveal melanoma clinically,

232 ne tumor load, occurrence of new lesions, or unequivocal progression of nontarget disease.

233 uch as measurement of size and definition of unequivocal progression, also are addressed.

234 ported by rapidly growing experimental data, unequivocal proof has been elusive.

235 These findings provide unequivocal proof of the allosteric nature of thrombin a

236 Unequivocal proof of the protonation site was obtained b

237 alize iron via a common mechanism, providing unequivocal proof that they do not.

238 early Chinese salt production have provided unequivocal proof.

239 separated from other HE-derived products for unequivocal quantification.

240 We show unequivocal quantitative evidence of large carnivore rec

241 ped disease recurrence following an initial, unequivocal radiologic complete regression after T-cell-

242 tion of the correct stereoisomer and enables unequivocal, rapid determination of complex molecular st

243 a small number of animal models by utilizing unequivocal rare disease mutations and targeted cognitiv

244 Our unequivocal realization of the "molecules to device" con

245 rate a paleomagnetic methodology that allows unequivocal recognition of detachment-mode seafloor spre

246 Currently, there is no unequivocal recommendation of an effective treatment for

247 The oldest unequivocal record of a sauropterygian is also from the

248 ntrol (IGC) targeting HbA1c fails to show an unequivocal reduction of macrovascular complications in

249 first study, the median time to the onset of unequivocal relief from an attack was 2 hours in the sub

250 imary end point was the time to the onset of unequivocal relief.

251 An unequivocal requirement for this approach is the biocomp

252 Unequivocal research on cAMP-mediated signaling in such

253 ectivity information on all isomers allowing unequivocal resonance assignment, and this approach to s

254 presentativeness of sampling and deliver the unequivocal response criteria required by the internatio

255 PCR yielded unequivocal results with adequate DNA isolated in 24 cas

256 classical NMR data analysis fails to provide unequivocal results.

257 Pappaceras is the earliest known unequivocal rhinocerotoid, and the holotype of the new s

258 These data demonstrate an unequivocal role for common genetic variants in the etio

259 ation of Wnt/beta-catenin signaling plays an unequivocal role in colorectal cancer, but identificatio

260 Despite the unequivocal role of B lymphocytes as effecter cells in h

261 n screens and microarray data established an unequivocal role of VGSC SCN5A as a high level regulator

262 necessitates at least dual-element CSIA for unequivocal SA in the presence of degradation-induced is

263 idney transplantation is recommended, but no unequivocal screening strategy has yet been identified.

264 Even though FA cells demonstrate unequivocal sensitivity to crosslinkers, such as mitomyc

265 ion (N2E) in the amino terminal domain allow unequivocal separation of the two gating processes in a

266 erved at all internal energies, allowing for unequivocal sequence assignment.

267 To date, this precludes proposing an unequivocal sex-dependent susceptibility to influenza.

268 ocated in Central and East Asia, are showing unequivocal signs.

269 divergent Xenopus laevis XNC10 gene and its unequivocal Silurana (Xenopus) tropicalis orthologue, SN

270 on, new diagnostic primers were designed for unequivocal species and type assignments for RV-C isolat

271 bodies, in contrast, are very rare: only two unequivocal specimens have been reported, both from the

272 tu synchrotron infrared experiments show the unequivocal spectroscopic signature of the high-pressure

273 ntified DNA sequence variations that exhibit unequivocal statistical associations with many common ch

274 Herein we demonstrate that unequivocal step-change shifts in micelle populations oc

275 e, and nonclassical subsets, but there is no unequivocal strategy to dissect the latter 2 cell types.

276 been studied for nearly a century and yet an unequivocal structural description of this material rema

277 Revelation of unequivocal structural information at the atomic level f

278 mental PES and simulated spectra provides us unequivocal structural information to fully solve the gl

279 Despite its conserved presence, unequivocal study of Hrd3 function has been precluded by

280 ch as binocular rivalry, features periods of unequivocal subjective disappearances despite constant p

281 The unequivocal success of B-cell-depleting agents in reduci

282 n settlement of the island failed to provide unequivocal support for either scenario.

283 manipulation in nature, this study provides unequivocal support for frequency-dependent survival--an

284 ture of canonical alpha-helices and provides unequivocal support for our helix nucleation strategy.

285 Effort ratings provided unequivocal support for swallowing inhibition, with a th

286 Our findings provide the first unequivocal support for the existence of two modes of co

287 han humans may reflect problems in producing unequivocal support for the occurrence of teaching, rath

288 ies-level coevolved traits) does not provide unequivocal support for the theory.

289 to be deeply nested members of Annelida, and unequivocal support is found for Micrognathozoa as the s

290 the American Heart Association declares its unequivocal support of antiracist principles.

291 This result adds unequivocal support to the view that the PHC mediates co

292 odern, but are too poorly preserved to allow unequivocal taxonomic placement.

293 w taxon was claimed to represent the oldest "unequivocal" termitophile so far discovered, pushing bac

294 sts of 688 subjects who explicitly stated in unequivocal terms that they had received a (clinical) di

295 evidence to show that ocean warming poses an unequivocal threat to the persistence and integrity of k

296 tudies for complex cardiovascular disease is unequivocal, thus mandating the expansion of resources f

297 ting specific types of systemic amyloidoses, unequivocal typing of amyloid deposits is now essential.

298 Although ketamine has unequivocal uncompetitive inhibitory effects on N-methyl

299 l protein synthesis, thus allowing the first unequivocal visualization of two mtDNAs at the nucleoid

300 To the question in the title, we answer an unequivocal "yes" but maybe not necessarily in the areas