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1 oxanthin was mostly esterified and not free (unesterified).
2 production of 14,15-EET and by metabolism of unesterified AA, thereby preventing activation of the ne
3                These findings suggested that unesterified arachidonic acid in cells is a signal for i
4       We conclude that the cellular level of unesterified arachidonic acid is a general mechanism by
5 expression of COX-2 and FACL4 as "sinks" for unesterified arachidonic acid.
6 m ionophore also was prevented by removal of unesterified arachidonic acid.
7   Cholesterol effluxed to rHDL was initially unesterified but by 24 h this cholesterol was largely es
8 PC1 protein, which normally aids movement of unesterified cholesterol (C) from the endosomal/lysosoma
9                                        While unesterified cholesterol (C) is essential for remodeling
10  fatty acids (P < 0.05), and lower levels of unesterified cholesterol (P < 0.05), than nontransgenic
11 terification of phospholipid acyl chains and unesterified cholesterol (UC) by the enzyme lecithin:cho
12                                              Unesterified cholesterol (UC) that is taken up by the li
13 rincipally excreted from the body in bile as unesterified cholesterol (UC).
14                                              Unesterified cholesterol accumulates in late endosomes i
15 ic null npc2m/m zebrafish showed significant unesterified cholesterol accumulation at larval stages,
16                                              Unesterified cholesterol accumulation in the late endoso
17       There is accumulation of phospholipid, unesterified cholesterol and cholesterol ester in the co
18 , characterized by lysosomal accumulation of unesterified cholesterol and delayed induction of choles
19 (NPC1) arises from lysosomal accumulation of unesterified cholesterol and glycosphingolipids.
20  and is characterized by the accumulation of unesterified cholesterol and lipids in the late endosoma
21  extensive acellular areas that were rich in unesterified cholesterol and macrophage debris, the lesi
22 s characterized by lysosomal accumulation of unesterified cholesterol and multiple neurological sympt
23 sterol trafficking and cause accumulation of unesterified cholesterol and other lipids in lysosomal s
24 of either gene result in the accumulation of unesterified cholesterol and other lipids in the late en
25  or NPC2 cause intracellular accumulation of unesterified cholesterol and other lipids leading to neu
26 he enhancement in efflux of human fibroblast unesterified cholesterol and phospholipid (PL) by lipid-
27 ated livers had augmented secretion rates of unesterified cholesterol and phospholipid.
28 racellular cholesterol metabolism and making unesterified cholesterol available for steroid hormone p
29         Loss of ACAT2 activity may result in unesterified cholesterol being absorbed via an ABCA1-med
30  of tg-MPM with cholesterol or variations in unesterified cholesterol content appear to have little e
31                                 Doubling the unesterified cholesterol content of the plasma membrane
32 erent imaging modalities, and confirmed that unesterified cholesterol does accumulate in their OS and
33  border, whereas in the complicated lesions, unesterified cholesterol dominated in neovessel-containi
34 is clear that enrichment of fibroblasts with unesterified cholesterol enhances efflux of cholesterol
35 (m/z 385:m/z 369) was found to differentiate unesterified cholesterol from cholesterol esters.
36  are believed to facilitate the recycling of unesterified cholesterol from late endosomes/lysosomes t
37 es a protein involved in the net movement of unesterified cholesterol from the late endosomal/lysosom
38                                              Unesterified cholesterol had no apparent effect on parti
39 terized by the inappropriate accumulation of unesterified cholesterol in aberrant organelles.
40 tor in NPC mice altered the concentration of unesterified cholesterol in every organ in a manner cons
41  NPC2 gene that result in an accumulation of unesterified cholesterol in late endosomes/lysosomes (LE
42 isorder characterized by the accumulation of unesterified cholesterol in late endosomes/lysosomes, wh
43 mal storage disorder causing accumulation of unesterified cholesterol in lysosomal storage organelles
44 terized by the inappropriate accumulation of unesterified cholesterol in lysosomes [1].
45 ency triggers ER stress and sequestration of unesterified cholesterol in lysosomes, thereby activatin
46 sease is associated with the accumulation of unesterified cholesterol in nearly all tissues and with
47 lycolipids like GM2 and GM3 gangliosides and unesterified cholesterol in surviving Purkinje cells, as
48  the CM pathway changed the concentration of unesterified cholesterol in that organ.
49 erol homeostasis and extensive deposition of unesterified cholesterol in the skin and brain.
50 trate that the anti-cholesterol Ab recognize unesterified cholesterol in VLDL/IDL and LDL; high-densi
51  cells maintain significantly lower membrane unesterified cholesterol levels than mature-stage spleni
52 ion of the chromosome 8 locus is specific to unesterified cholesterol levels, whereas the chromosome
53  lipid stains and filipin for esterified and unesterified cholesterol or probed with antibodies to ap
54 dy mass but contains almost a quarter of the unesterified cholesterol present in the whole individual
55 atidylcholine, phosphatidylethanolamine, and unesterified cholesterol provided evidence that anionic
56 d annealing of PL-rich HDL models containing unesterified cholesterol results in double belt structur
57 ) disease, a mutation in NPC1 protein causes unesterified cholesterol to accumulate in the lysosomal
58 r NPC2 protein function that is required for unesterified cholesterol transport from the endosomal/ly
59 h postnatal, accumulation of filipin-labeled unesterified cholesterol was clearly evident not only in
60  and, in addition 4) the level of macrophage unesterified cholesterol was not rate-limiting for this
61                               Esterified and unesterified cholesterol was present in all drusen and b
62 e effector, and phosphatidylethanolamine and unesterified cholesterol were essentially neutral diluen
63 abnormal accumulation of GM2 ganglioside and unesterified cholesterol within late endosomes and lysos
64 ns in late endosomes and lysosomes to efflux unesterified cholesterol, and its deficiency causes Niem
65 studied on r-HDL made of palmitoyloleoyl-PC, unesterified cholesterol, cholesteryl ester, and apolipo
66 aracterized by intracellular accumulation of unesterified cholesterol, sphingolipids, and other lipid
67 t that it autoxidizes at 4 times the rate of unesterified cholesterol, the product distribution is la
68 ), containing predominantly phospholipid and unesterified cholesterol, was morphologically heterogene
69 advanced lesions accumulate large amounts of unesterified cholesterol, which is a potent inducer of m
70 -onset hypercholesterolemia characterized by unesterified cholesterol-rich abnormal lipoproteins (lam
71 preventing the negative feedback elicited by unesterified cholesterol.
72 at contained PC, apo AI, and, in some cases, unesterified cholesterol.
73 alized with lipid deposits, mainly formed by unesterified cholesterol.
74  yet there was no reciprocal accumulation of unesterified cholesterol.
75 ed solubilization of phospholipid (PL)/free (unesterified) cholesterol (FC) bilayer membranes in cell
76 ve uptake of CE and efflux of cellular free (unesterified) cholesterol (FC) from COS-7 cells expressi
77 es possess four pathways for exporting free (unesterified) cholesterol to extracellular high density
78 nt formulas derived from soy or bovine milk, unesterified choline, phosphocholine, glycerophosphochol
79 ulfotransferase (SULT1A3) when compared with unesterified CoA and short chain-length acyl-CoAs.
80  nanoparticle that acts as a transporter for unesterified DHA (LDL-DHA) and demonstrates selective cy
81 ng cholesterol oxidase to selectively render unesterified DHE nonfluorescent.
82  the [3H]8,9-EET uptake by cells remained as unesterified EET.
83 4 modulates GSIS by regulating the levels of unesterified EETs and that arachidonate controls the exp
84 ellulose formation and an increased ratio of unesterified/esterified pectin.
85 nism that appears to involve substitution of unesterified (exogenous) sterol from HDL for plasma memb
86                        The heart can utilize unesterified FA bound to albumin or FA obtained from lip
87                           The association of unesterified fatty acid (FA) with the scavenger receptor
88 ding protein (AFABP) is believed to transfer unesterified fatty acids (FA) to phospholipid membranes
89 lmitin (DP) and saturated or polyunsaturated unesterified fatty acids (PUFAs) on both the structure o
90                           The rates by which unesterified fatty acids and cholesterol move through an
91 tty acyl coenzymes A (acyl-CoAs) rather than unesterified fatty acids as the small-molecule ligands r
92 ts showed for the first time the presence of unesterified fatty acids in the nucleus of living cells
93  necessary if the PXA1 transporter delivered unesterified fatty acids into the peroxisomal matrix.
94 provide an in vivo test of this specificity, unesterified fatty acids were generated within the cellu
95  of phospholipids into lysophospholipids and unesterified fatty acids.
96                                          The unesterified fluorescent VLC-PUFAs distributed either eq
97 ol-rich liposomes having >90% cholesterol in unesterified form.
98 ructure on ABCA1-mediated efflux of cellular unesterified (free) cholesterol (FC) and phospholipid (P
99 e effects of apoA-I modification on cellular unesterified (free) cholesterol (FC) efflux, three recom
100 hatidylcholine (PC), sphingomyelin (SM), and unesterified (free) cholesterol (FC) from J774 macrophag
101 entrations and proportions of esterified and unesterified HDL-C.
102  that influence a component of HDL-C-namely, unesterified HDL2a-C.
103     Nonetheless, they have not been detected unesterified in the free form, presumably because of the
104 racemic PGs, particularly PGD2, were present unesterified in urine from normal animals and humans and
105 CFA-CoA) and low affinity (Kd=58-296 nm) for unesterified long chain fatty acids (LCFAs).
106                                     Although unesterified long chain fatty acids interact with peroxi
107 ls progressively accumulate large amounts of unesterified or "free" cholesterol (FC), a process that
108                                              Unesterified, or "free," cholesterol (FC) is a potent in
109 matory mediators and macrophages with excess unesterified, or "free," cholesterol (FC).
110 clerotic lesions accumulate large amounts of unesterified, or "free," cholesterol (FC).
111 mpacts wall strength and cell adhesion since unesterified pectin regions can cross-link via Ca(2+) io
112                          The distribution of unesterified pectins in cyt1 cell walls is also disrupte
113 ickness of the cell walls are irregular, and unesterified pectins show an abnormally diffuse distribu
114                                    Using the unesterified plant sterol, sitostanol (SIT), as a nonexc
115 veals a biologically important mechanism for unesterified PUFA transport to intracellular compartment
116 not its homolog LRP6, selectively transports unesterified PUFAs into a number of cell types.
117 ters Mfsd2a, CD36 and FATP2, LRP5 transports unesterified PUFAs via internalization to intracellular
118 olymers include spectra of HG molecules with unesterified regions that are separable from methylester
119  idea that the cellular uptake and efflux of unesterified retinol by enterocytes is mediated by lipid
120                                              Unesterified retinol taken up by the enterocyte is compl
121 umstances there is substantial absorption of unesterified retinol via the portal route.
122  a reconstituted HDL, made with radiolabeled unesterified SIT, UC, and cholesteryl esters (CE).
123 total cholesterol (i.e., both esterified and unesterified); spectrotype 2 comprising glucose signals
124                                              Unesterified sterol modulates the function of eukaryotic
125 fic protein shown for the first time to bind unesterified sterol with high affinity.
126 c and most RBC pathologies and corrected the unesterified to total cholesterol ratio (0.3) and associ
127 ered from SR-BI KO mice in that the ratio of unesterified to total plasma cholesterol was normal, fem
128 in RBC maturation and abnormally high plasma unesterified-to-total cholesterol ratio (0.8) with assoc
129                Under the conditions in which unesterified tRNA binds to both the P- and E-sites of no
130                                              Unesterified tRNA inhibited the disassembly of the post-
131                                      RRF and unesterified tRNA similarly inhibited the binding of N-a
132 ed with filipin to reveal esterified (EC) or unesterified (UC) cholesterol (n = 20, 17-92 years).
133 rs is as severely impaired as degradation of unesterified very long-chain fatty acids in X-ALD and is

 
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