ライフサイエンスコーパス: unexpected

1 ezo's structure and function that were fully unexpected.

2 imaging and transcriptomics study reveals an unexpected 2-step process of biotransformation.

3 We found an unexpected abundance of chemotropic proliferation and gu

4 gn with identical stimulus material for both unexpected action and unexpected inhibition using functi

5 , and Bayesian analyses, we demonstrate that unexpected action elicited by an unexpected go signal an

6 Furthermore, the stronger the unexpected action-related activity in the STN region was

7 n cell death and additionally revealed their unexpected activity in suppressing axon regeneration.

8 y, we have produced and examined a number of unexpected acyl intermediates of variable photolytic sta

9 The unexpected additional binding site was identified betwee

10 However, Rab27a knockdown cells had an unexpected advantage at initial steps of metastatic seed

11 ithout major modifications and the number of unexpected adverse events occurring in approved protocol

12 There were no unexpected adverse events with (177)Lu-PSMA retreatment.

13 Unexpected allergic reactions to peanut are the most com

14 These effects of the IT mutation, along with unexpected alterations in ion selectivity, were generall

15 During morphogenesis, we found several unexpected alterations to cytokinesis, including apical

16 e synthesis of N-alkoxyazomethine ylides, an unexpected aminal byproduct was generated during our att

17 efects found in ascidian samples can play an unexpected and decisive role in the permanent renewal an

18 mers with specific monomer sequences exhibit unexpected and distinct charge transport pathways that e

19 The word naturally conjures fears of unexpected and freakish changes.

20 hree-dimensional porous media and uncover an unexpected and general mixing mechanism that strongly en

21 of the zebrafish infection model, revealing unexpected and important concepts underlying infectious

22 and decreased beta-lactam susceptibility was unexpected and is of public health concern.

23 that accounts for these benefits may explain unexpected and seemingly irrational thought patterns, su

24 Here we describe the formation of an unexpected and unique family of hollow six-stranded heli

25 o donation from persons who die following an unexpected and unsuccessfully resuscitated cardiac arres

26 phics of UM, these accumulations of cases is unexpected and worth additional exploration.

27 The unexpected anomaly features an infinite number of single

28 We here provide an unexpected answer, founded on our observation that photo

29 This was unexpected, as ABCC1 has strong selectivity for glutathi

30 ker growth by ion irradiation is a novel and unexpected aspect of space weathering.

31 These findings reveal an unexpected aspect of theta-based hippocampal encoding an

32 nes that, upon further analysis, revealed an unexpected association between the aliphatic glucosinola

33 The structures reveal an unexpected asymmetric A(5)B(2) subunit assembly where th

34 similarity to targets that were contextually unexpected at encoding compared with expected ones.

35 Many of these associations are unexpected based on efficacy data or evidence-based guid

36 This was unexpected because expression of the T3SS is usually rec

37 h1-h2 linker region is predicted to form an unexpected beta-hairpin that may represent an early amyl

38 r designing highly selective inhibitors with unexpected binding modes.

39 an be mined for relevant patterns, revealing unexpected biological activity that is useful for many s

40 or VIII (FVIII) and most often presents with unexpected bleeding.

41 ar targets that contain C-patches reveals an unexpected breadth of binding affinities.

42 (13)C isotope labeling identifies an unexpected bromine migration en route to an alpha-select

43 In summary, we find that PbgA has an unexpected but essential role in the regulation of LPS b

44 Formation of this unexpected byproduct presented an opportunity to streaml

45 TPX2 has the unexpected capacity to directly recruit gamma-TuRC as we

46 New antidiabetic agents show unexpected cardioprotective benefits.

47 rus disease 2019 (COVID-19) pandemic exposes unexpected cardiovascular vulnerabilities and the need t

48 in fact, is formed via the connection of two unexpected catalytic cycles, with acetate being only the

49 nal activity at these genes was linked to an unexpected CDK9-dependent compensatory feedback loop tha

50 We implicate unexpected cell types in diseases such as macular degene

51 structure of CaBaZn(2)Ga(2)O(7) leads to an unexpected cell volume expansion of CaBa(1-x)Pb(x)Zn(2)G

52 Our findings will help resolve unexpected challenges and biases in on-chip experiments

53 about how motor regions respond to rapid and unexpected changes in action selection.

54 e-edited crops; (ii) the characterization of unexpected changes that might affect safety; and (iii) b

55 ack to researchers who submit sequences with unexpected characteristics.

56 n where the onset of channel flow creates an unexpected, charge-dependent accumulation of colloidal p

57 Recent Zika virus (ZIKV) outbreaks and unexpected clinical manifestations of ZIKV infection hav

58 using the least likely technique to generate unexpected compositional changes; and (iii) onerous regu

59 tudy shows that one of them does while using unexpected compounds.

60 checkpoint function of PD-L1 and provide an unexpected concept that GSDMC/caspase-8 mediates a non-c

61 Recent work has made an unexpected connection between these metabolites and DNA

62 ents and differential stress, with sometimes unexpected consequences.

63 deletion of N-terminal residues revealed an unexpected contribution of the receptor N terminus to ch

64 ts, sites of regulated accessibility, and an unexpected cooperation with SOX transcription factors.

65 We observe unexpected correlations within and between pathways that

66 rroptosis partly through AMPK and reveals an unexpected coupling between ferroptosis and AMPK-mediate

67 ity over previously developed 2-D models and unexpected, current-driven, strong (to a maximum of abou

68 Unexpected DDD was rare, occurring in 0.18% of all trans

69 ement disorders, and elevated risk of sudden unexpected death in epilepsy.

70 related injuries, increased chance of sudden unexpected death, and unfavourable treatment outcomes.

71 They suffer an unexpected degree of morbidity.

72 our DeltaSILAC profiling revealed a global, unexpected delaying effect of many phosphosites on prote

73 uired for NL enrichment of BAF, revealing an unexpected dependence on a single LEM-D protein.

74 Prompted by the unexpected detection of an off-target ribosome alteratio

75 ients with few surgical complications and no unexpected device-related AEs.

76 diclofenac taurine conjugate (DCF-M403) and unexpected diclofenac methyl ester (DCF-M310.03).

77 anomalous intracellular dynamics, revealing unexpected differences in behavior between closely relat

78 Additionally, we uncover unexpected differential distribution of distinct miRNAs

79 gnaling molecules, MAVS, STAT1, and STAT2 An unexpected differential response of enhanced replication

80 tient and surgical variables associated with unexpected difficulty and high workload.

81 The methylalkyne-derived substrates gave unexpected dimeric structures in good yield with excelle

82 intain the broad reflection band without any unexpected dips.

83 Here, we report the unexpected discovery of (L)Pd(II)(OAc)(2)-mediated oxida

84 d luciferase-refolding assays, we report the unexpected discovery of a second peptide-binding site in

85 Moreover, we identified an unexpected, discrete behavior of the m-loop, which media

86 e in hedging against future climate or other unexpected disruptions to the food system.

87 These data establish an unexpected diversity in NK cell synaptic secretions.

88 Comparative genomics reveals an unexpected diversity in the molecular mechanisms underly

89 These results underscore the unexpected diversity of pathways to resistance and the i

90 motion and atomistic calculations unveil the unexpected dominance of nonscrew character dislocations

91 l range of extant taxa, Mesodescolea reveals unexpected early morphological and ecophysiological tren

92 These data reveal the unexpected ease with which polymerase exchange occurs in

93 re, it is important to address the potential unexpected effect of JQ1 treatment, such as cell invasio

94 These results show an unexpected effect of proliferation status in regulating

95 Our findings indicate that JQ1 has an unexpected effect of promoting invasion in prostate canc

96 ociated mutations in this domain reveals its unexpected effect on incorporating Pol epsilon into the

97 as a potent means to control maturation with unexpected effects on electrical and mechanical function

98 d the behavior and position of flies but had unexpected effects on individual and population asymmetr

99 a truncated form has been crystallized in an unexpected, elongated form.

100 in LC-HRMS data resulted in the detection of unexpected emissions from FPIs, demonstrating the value

101 Recent reports of unexpected emissions of CFC-11 raise the need to better

102 We demonstrate that this unexpected enrichment can be observed for two different

103 These results revealed an unexpected environmental factor that controls the death-

104 role of this enzyme in cancer, and found an unexpected essential role for NMT1 at promoting lysosoma

105 The structure uncovers an unexpected, eukaryotic specific and dynamic fidelity che

106 When encountering unexpected event changes, memories of relevant past expe

107 eory of unexpected events suggests that such unexpected events just like global stopping recruit a fr

108 The current theory of unexpected events suggests that such unexpected events j

109 Saudi Arabia (KSA), were precipitated by the unexpected existence of a closely related species, the N

110 tructurally related catalysts, and a totally unexpected facial selectivity inversion was also noticed

111 hological tests, the finding of frequent and unexpected failure in a range of clinical conditions rai

112 Unexpected features are observed, especially the pH evol

113 and reduced anxiety behaviours, plus several unexpected features, including significant resistance to

114 This unexpected finding of increased constraint in many longe

115 This unexpected finding, along with our discovery that positi

116 ing techniques provide detailed insights and unexpected findings for the unique reaction mechanism.

117 These unexpected findings highlight the SIK1/HDAC7 signaling a

118 Unexpected findings included capsid protein-transcriptio

119 port, high-resolution ocular imaging reveals unexpected findings that reject previous hypotheses.

120 The unexpected findings were that mutations K170A, E227A, K3

121 ompositions and temperatures, as well as the unexpected formation of a secondary, rocksalt-type phase

122 Visual motion speeds were manipulated during unexpected forward and backward shoulder pulls.

123 Altogether, we reveal an unexpected function for TruB1 in promoting let-7 maturat

124 This study reveals an unexpected function of XPO5 for recognizing and facilita

125 proves pathology in a mouse model through an unexpected GALC-dependent mechanism, i.e., by providing

126 e and prophage induction and also identified unexpected gene expression states, including the heterog

127 Together, these studies unravel unexpected gene regulation directly mediated by rRNA and

128 However, we report varying probabilities of unexpected germline recombination in distinct Cre driver

129 strate that unexpected action elicited by an unexpected go signal and unexpected inhibition elicited

130 We thus reveal that Tfr cells have an unexpected helper role in promoting food allergy and may

131 We report an unexpected heterogeneity within the naive T cell compart

132 Here, we report an unexpected high flexibility in C:N and C:P values of sap

133 The discovery of an unexpected high-concentration doping effect in defective

134 m and single-molecule trajectories reveal an unexpected high-degree of asynchrony in translation acti

135 s of this metallocenate family, including an unexpected high-spin S = 3/2 ground state for the 19e(-)

136 yridine-4-yl-methanethiol ligand to adopt an unexpected highly conductive stacked structure between t

137 increased representational dissimilarity for unexpected highly similar foils in DG and CA3.

138 memory accuracy is enhanced selectively for unexpected highly similar foils, suggesting expectation

139 f pathogen and stress immunity, revealing an unexpected homeostatic relationship between development

140 Structures of insect poxins reveal unexpected homology to flavivirus proteases and enable i

141 They also highlight an unexpected immunological divergence of Qa-1(b)/HLA-E fun

142 Clinical studies have observed an unexpected improvement in hemoglobin and RBC transfusion

143 compensatory cell enlargement, a phenomenon unexpected in roots.

144 Here, we found unexpected increases in N fixation rates in the soil, fo

145 tion elicited by an unexpected go signal and unexpected inhibition elicited by an unexpected nogo sig

146 ulus material for both unexpected action and unexpected inhibition using functional magnetic resonanc

147 sentational differences between expected and unexpected inputs were prominent for moderate to high le

148 from a high transmission setting, providing unexpected insights into the biology and transmission of

149 This led to unexpected insights into the remarkable flexibility of t

150 rid network structure, but they also provide unexpected insights into the structure-stability relatio

151 adigm to computational complexity, with some unexpected insights provided by fields as varied as zool

152 is of CB2-selective agonists design, and the unexpected interaction of cholesterol with CB1, suggesti

153 HOS function and redox signalling through an unexpected interaction with phospholipids, with profound

154 R agonism with 100% accuracy, and identified unexpected interactions for the receptors ADRA2B, HCAR3,

155 DSB repair by inducing R-loops, revealing an unexpected interplay between distinct ROS-induced DNA le

156 rse biosynthetic transformations that reveal unexpected intersection with amino acid, carbohydrate, a

157 We observed unexpected intracellular activity profiles for a number

158 Further domain analysis revealed an unexpected intramolecular interaction that might control

159 at, instead of a conventional IC pathway, an unexpected intramolecular singlet fission (iSF) process

160 Taken together, our study reveals an unexpected isoform diversity of MYO7A expression in the

161 s showed more dissimilar representations for unexpected items, with dentate gyrus (DG) and CA3 being

162 Here, we report an unexpected, kinase-independent function for AURKA in DNA

163 These findings reveal an unexpected let-7-independent function of LIN28B in trans

164 In contrast, radial nerve showed an unexpected level of complexity with the expression of 3,

165 Recent work reveals unexpected ligand binding profiles for these newly ident

166 We show that NAD(+) is an unexpected ligand of the armadillo/heat repeat motifs (A

167 tide-gated channels(5), and may represent an unexpected link between depolarization- and hyperpolariz

168 Implicated mechanisms include an unexpected link between puberty timing and natural hair

169 following replication stress, uncovering an unexpected link between stress and sister chromatid cohe

170 urated with glutamine in vivo and provide an unexpected link between the serine shuttle pathway, resp

171 time, this shift in perspective establishes unexpected links with developmental and ecological psych

172 e global tonotopic maps, while uncovering an unexpected local variability in the stimulus preferences

173 ery similar communities, characterized by an unexpected low diversity of Phytophthora species, with t

174 This unexpected malleability of the replisome might allow it

175 Main outcome measures were incidence of unexpected management changes (change in or extended pos

176 his process, we identified and characterized unexpected mannose oligomers that are alpha(1-2/3) linke

177 We reveal unexpected many-body interactions in this colloidal syst

178 We analyse 24 separate episodes of unexpected marketplace closure by inspecting 133 million

179 This study describes an unexpected mechanism by which RNA-binding protein, MBNL1

180 rowing beta-hematin crystals to elucidate an unexpected mechanism employed by two widely administered

181 as abolished by Src inhibitors, revealing an unexpected mechanism in which SFKs autoinhibit their act

182 Our work has identified an unexpected mechanism that controls intestinal disease to

183 eathering by S. commune could be reached and unexpected mechanisms like quartz dissolution linked to

184 etallic reactivity of gold(III) has revealed unexpected mechanistic avenues, which can open when the

185 By structural studies, we characterized its unexpected Mg(2+)-independent binding mode.

186 s or drug candidates, revealing UMI-77 as an unexpected mitophagy activator.

187 We describe an unexpected mitotic peak in the abundance of ergosterol a

188 Our results demonstrate an unexpected mixed phenotype of apoB-reactive autoimmune T

189 The structures reveal an unexpected mode of binding in which trametinib directly

190 dration and molecular crowding, revealing an unexpected mode of globally programmed phase separation

191 omplex I+III(2) turnover rate, indicating an unexpected molecular adaptation for supercomplexes stabi

192 Overall, our findings demonstrate an unexpected molecular mechanism for N(6)-mA function via

193 ial mutant collection and identified several unexpected mutations.

194 In the organic carbon PRB, unexpected negative europium anomalies were observed, re

195 nal and unexpected inhibition elicited by an unexpected nogo signal recruited the same fronto-basal-g

196 uli from previous work showing out-of-key or unexpected notes may elicit a musical analogue of langua

197 This unexpected observation led us to find additional mutatio

198 Our entry was the unexpected observation that deletion of Bithorax complex

199 erogeneous, biological networks, which offer unexpected opportunities for network-based identificatio

200 ural products provides unique challenges and unexpected opportunities for the development of new reac

201 care from in-network physicians may receive unexpected out-of-network bills ("surprise bills") from

202 ding those circulating in the community from unexpected outbreaks.

203 ine scenarios in which infection may lead to unexpected outcomes in response to global change.

204 Here, we reveal unexpected overlap between signaling and regulation of t

205 This work suggests an unexpected parallel between the formation of physiologic

206 This unexpected pattern of divergence indicates that the Form

207 The unexpected performance of the catalyst is realised follo

208 ared to when visual motion is paired with an unexpected perturbation of the body.

209 Moreover, we explain this unexpected phase complexity in terms of a simple microsc

210 and underlying molecular mechanisms of this unexpected phenomenon.

211 Instead, we report an unexpected phenotype of nondiabetic obesity beginning at

212 With X-ray crystallography, we detected an unexpected photochemical intermediate trapped in a cryst

213 omically defined interfaces may give rise to unexpected physics.

214 lybdenum oxide (MoO(2) ) flakes that exhibit unexpected piezoelectric-like response are fabricated, a

215 ficantly larger vocal response magnitudes to unexpected pitch-shifts and significantly smaller vocal

216 On the basis of our analysis, we find an unexpected PL increase (~ 540 nm) at the oil/shell inter

217 rization and hyperactivity, demonstrating an unexpected positive feedback loop to persistently promot

218 Here we highlight unexpected positives that we have found and hope will pe

219 These findings illustrate an unexpected potential interface between GrB and innate im

220 These results revealed unexpected properties of hydroxynorketamine that warrant

221 This unexpected property is attributed to the formation of de

222 allowed us to highlight unique samples with unexpected reactivity behaviors throughout hydrotreatmen

223 ia, with increased probability for girls and unexpected reduced probability for boys, possibly due to

224 nd DFT calculations provide insight into the unexpected regiodivergence and explain the different mec

225 PKC-regulated DAT internalization and reveal unexpected region-specific differences in PKC-stimulated

226 in the trans isomer are responsible for this unexpected relative cis/trans stability.

227 sed its cognitive complexity, as well as its unexpected reliance on portions of the anterior PFC (aPF

228 An unexpected, remarkably stable dimanganese product, (H(2)

229 Our results highlight an unexpected repurposing of a master regulator of male-spe

230 trol and membrane homeostasis and suggest an unexpected requirement for VLCFAs in Ole1 function.

231 Our data settle controversies, revealing unexpected resistance mechanisms.

232 To address this unexpected result, we performed genome-wide CRISPR scree

233 decrease autophagosome numbers suggesting an unexpected RILP role in autophagosome biogenesis.

234 MRP proteins shared with RNase P undergo an unexpected RNA-driven remodeling that allows them to bin

235 e approach is also presented that highlights unexpected roadblocks and how novel solutions were devel

236 Finally, we identified an unexpected role for ATOH7 expression in regulation of ph

237 (2020) demonstrate an unexpected role for dopamine D(1) receptors on astrocyte

238 Overall, this study reveals an unexpected role for Fbw7 in the survival and fitness of

239 imulated Ca(2+) release in cells and find an unexpected role for Galpha(q) in Gbetagamma-dependent ac

240 Together, these findings demonstrate an unexpected role for metabotropic NMDARs and postsynaptic

241 Here, we uncover an unexpected role for PARG in coordinating the induction o

242 ugh impacting tRNA methylation and reveal an unexpected role for TET enzymes in regulating multiple n

243 microtubule dynamics, and here, we report an unexpected role for the atypical actin motor Myo6 in cre

244 Here, we describe an unexpected role for the radial fiber scaffold in directi

245 (2020) reveal an unexpected role for TRAIL receptors in ER-stress-induced

246 onstrate that CHK2-mediated autophagy has an unexpected role in reducing ROS levels via the removal o

247 both phage-specific mechanisms, such as the unexpected role of cyclic-di-GMP in host sensitivity to

248 yase (CSE)-deficient mice, we demonstrate an unexpected role of H(2)S in Mycobacterium tuberculosis (

249 Our findings uncover an unexpected role of non-NLRP3 inflammasomes for CNV and s

250 Here, we report an unexpected role of nutrient-sensing O-linked beta-N-acet

251 is of complex brain maladies, and reveals an unexpected role of oligodendrocytes in Parkinson's disea

252 nduce inflammasome activation and reveals an unexpected role of staphylococcal lipoproteins in EV bio

253 Here, we report an unexpected role of TDP-43 in the formation of dynamic, r

254 ts function in the zebrafish and revealed an unexpected role of this pathway in vertebrate embryonic

255 s activators of the viral life cycle, and an unexpected role of XBP1u as a potent repressor of both X

256 layers of the infralimbic PFC, highlighting unexpected roles for both CCK+ interneurons and endocann

257 r and C. humicola species complexes may play unexpected roles in the pathogenesis of asthma.

258 We corroborated this unexpected scheme for beta-strand organization using mul

259 rations need to be accounted for to mitigate unexpected seismic hazards in the presence of the site-s

260 defensive response elicited by an immediate, unexpected sensory event, which is potentiated when evok

261 These results demonstrate an unexpected sevoflurane-induced increase in neuronal acti

262 nociceptor-enriched translatomes and reveal unexpected sex differences in one of the oldest known no

263 hange, and reveal a similarly consistent and unexpected shift in body shape.

264 drug repurposing and understanding of their unexpected side effects.

265 An unexpected side product formed through 4-exo-trig radica

266 Such unexpected slow process of excited-state transformation

267 -terminal fragment of thrombospondin-1 as an unexpected SMAP component that contributed to target kil

268 This was due to unexpected social exploitation: snowflake yeast, which d

269 ronments with unique properties that lead to unexpected solvation effects on chemical and photochemic

270 Here, we uncovered an unexpected specific interaction of LOTUS domains with G-

271 yporphins A (1), R (8), and E (9), revealing unexpected stereochemical variation within the series.

272 teractor 1 (GIT1), which we found to play an unexpected stimulatory role in GPCR-mediated eNOS signal

273 de (DC) response (startle, freeze) to sudden unexpected stimuli is a potential indicator of animal af

274 ect the degree of "surprise" associated with unexpected stimuli.

275 We report an unexpected stimulus-dependent diversity in Na(V) channel

276 termetallics and semiconductors and can have unexpected structures and properties because of the exot

277 ine bone marrow stem cells, demonstrating an unexpected subtype-specific role for H1 in granulopoiesi

278 sis of reactions of small aldehydes gives an unexpected switch in stereopreference, leading to format

279 bule (IPL) were modulated by prior belief on unexpected targets compared with expected targets.

280 Here, we describe unexpected temporal compensatory responses in biomineral

281 coordinates movement times with expected and unexpected temporal events.

282 protein-isoforms, which might contribute to unexpected therapeutic activity or adverse side effects.

283 Such differences may suggest unexpected therapeutic targets for alleviating periodont

284 ders of magnitude in ultrathin sheets and an unexpected thickness-dependent modulation of the ultrafa

285 eact to anthropogenic disruption, leading to unexpected threats for wildlife and the environment.

286 eir packing into a novel superstructure with unexpected three-fold rotational symmetry in a single tw

287 ade 3-4 events in 3 patients (7.7%), with no unexpected toxicities.

288 gimens were generally well tolerated without unexpected toxicities.

289 cluding the most challenging aspects of this unexpected transition, the advantages and limitations of

290 These results reveal an unexpected TRDMT1-m(5)C axis that promotes HR, suggestin

291 We reveal unexpected variation in patterns of DNA methylation acro

292 umonia, acute respiratory distress syndrome, unexpected ventilation).

293 We uncover an unexpected versatility in cytoskeletal form that may pro

294 ofound conductivity reduction accompanied by unexpected volume expansion is observed in CrN films.

295 are of great importance as they evidence how unexpected, water-dependent proton diffusion can be at t

296 ntersected with discoveries in immunology in unexpected ways to rapidly inform emerging treatment str

297 mistry, molecules under tension can react in unexpected ways.

298 al protein function, impacting physiology in unexpected ways.

299 affected the individual scalae pressures in unexpected ways: SCD increased P(SV) below 1 kHz, but ha

300 alaxies and galaxy clusters have reported an unexpected x-ray emission line around 3.5 kilo-electron