1 Unexpectedly,
50 modules of genes were robustly defined
2 Unexpectedly,
a few phenotypically masculinised fish are
3 Unexpectedly,
a moderately high-amino acid diet also blo
4 ytes, and its levels drop after meiosis, but
unexpectedly,
a significant fraction is present througho
5 HVDC cables we found that there were DC and
unexpectedly AC components.
6 induction, while talin1-deficient dermal DCs
unexpectedly accumulated in the dermis despite their act
7 nfirmed by X-ray crystallography and yielded
unexpectedly accurate and stable predictions without the
8 class of presumptive antiviral factors that
unexpectedly act as important proviral enhancers during
9 how that: 1) the PPARgamma antagonist GW9662
unexpectedly activates PPARdelta-mediated signaling in m
10 vely large prospective application providing
unexpectedly active molecules with IC(50)'s from 2340 to
11 Unexpectedly,
acute cerebrovascular disease is also emer
12 The core of the complex
unexpectedly adopts a U-shaped head-to-head topology to
13 Unexpectedly,
aged Trem2-/- mice showed superior cogniti
14 Unexpectedly,
also benzyl ether protecting groups can en
15 in high CO(2) -induced stomatal closure and,
unexpectedly,
also in low CO(2) -induced stomatal openin
16 Unexpectedly,
an asymmetric AARS distribution was observ
17 Unexpectedly,
and despite including traditional ionic li
18 Unexpectedly,
ARID1A was also the top candidate in regar
19 iabetes (glycohemoglobin [HbA1c] >=8.0%) was
unexpectedly associated with better TB treatment outcome
20 Lactobacillus reuteri as a commensal species
unexpectedly associated with exacerbation of EAE in a ge
21 Unexpectedly,
astrocytes and microglia also acquired per
22 ens reduces GFP::DBL-1 fluorescence and acts
unexpectedly at the level of dbl-1 transcription.
23 GMP accumulate in the BM in SpA and,
unexpectedly,
at extramedullary sites: in the inflamed j
24 Unexpectedly,
bacterial burden in prostates challenged w
25 Unexpectedly,
bacterial diversity (ASV, Faith PD and Sha
26 Unexpectedly,
better light-gathering ability was linked
27 XptA1 reveal that heparins/heparan sulfates
unexpectedly bind to different regions of the shell doma
28 t the discovery of iterative T1PKSs that are
unexpectedly both abundant and widespread in Streptomyce
29 -derived HLA class I ligands representing an
unexpectedly broad panel of 123 HCMV antigens.
30 quency stimulation of PAG afferents in vitro
unexpectedly causes long-term potentiation.
31 upts cGMP binding to the pocket, but it also
unexpectedly causes PKG1 to have high activity in the ab
32 forces and its weight was either constant or
unexpectedly changed in between trials.
33 Unexpectedly,
chromatin regulatory proteins are enriched
34 Unexpectedly,
CN shows SLiM-dependent proximity to centr
35 due to reduced cubilin function could be an
unexpectedly common benign condition in humans that may
36 ies show that molecular convergence plays an
unexpectedly common role in the evolution of convergent
37 Unexpectedly,
components of the OMC are organized in a 1
38 Our findings reveal an
unexpectedly comprehensive functional repertoire for Hsp
39 this work, we address this issue based on an
unexpectedly concise and insightful analytical formulati
40 Unexpectedly,
concomitant to a poleward migration, futur
41 Unexpectedly,
conduction was unimpaired in the locked ch
42 rstanding of the clinical outcomes that have
unexpectedly contradicted preclinical observations.
43 projections generate freezing behavior and,
unexpectedly,
contribute to associative fear learning.
44 plasmic-reticulum-associated response, quite
unexpectedly contributes to the nuclear/cytoplasmic HSR
45 Unexpectedly,
coordination of phosphotyrosine is achieve
46 Unexpectedly,
CSF WBCs were more likely to normalize in
47 Unexpectedly,
CXL146 treatment rapidly and dose-dependen
48 Unexpectedly,
de novo and maintenance methylation activi
49 After the peak, g/V
unexpectedly declines and settles into a plateau that in
50 erved substrates for TRIM proteins but also,
unexpectedly,
deep evolutionary connections between TRIM
51 Unexpectedly,
depletion of macrophages in obese mice enh
52 Unexpectedly,
DFO failed to induce EBV reactivation in c
53 o low-energy triplet excitons that have been
unexpectedly difficult to dissociate into free charges.
54 Allergen-induced AHR was
unexpectedly diminished in Rgs4(-/-) mice, a finding ass
55 y stimulator of interferon genes (STING), to
unexpectedly directly generate HRD.
56 Despite this conservation, we
unexpectedly discovered a disparate distribution for rha
57 Moreover, we
unexpectedly discovered that ADAR proteins bind dsRNA su
58 We
unexpectedly discovered that DX314, but not all-trans-RA
59 receptor, and cluster of differentiation 8a,
unexpectedly displayed substantial Golgi localization wh
60 Unexpectedly,
distinct but overlapping VMHdm(SF1) subpop
61 mpartment of the human genome, which encodes
unexpectedly diverse cell- and tissue-selective regulato
62 Our results reveal an
unexpectedly diverse repertoire of PRC2 binding configur
63 Unexpectedly,
division of the large Chlamydomonas chloro
64 coids highly stimulated macrophage mobility;
unexpectedly,
DPP4 mediated the glucocorticoid-induced m
65 Unexpectedly,
Drosophila (d) ACOX1 is mostly expressed a
66 Our results reveal an
unexpectedly dynamic nature of HSC residence in the BM a
67 Unexpectedly,
dysfunctional alloreactive B cells acquire
68 Furthermore, and perhaps
unexpectedly,
e2 significantly increased risk of acute/s
69 Our study therefore reveals the
unexpectedly early and systemic onset of cDC1 dysregulat
70 nd that hESCs commit to exiting pluripotency
unexpectedly early.
71 Unexpectedly,
early priming of CD4(+) T cells against tu
72 ) family-specific inhibitor FR900359 (FR) is
unexpectedly efficacious in silencing the signaling of G
73 Unexpectedly,
Elite varieties exerted a stronger genotyp
74 Unexpectedly,
endogenous Mov10 promotes HCV replication,
75 l burst firing by reducing K(+) release, but
unexpectedly enhanced their tonic firing, as water resor
76 Unexpectedly,
EpiGo-KRAB-induced heterochromatin-like do
77 ph node homing and antigen presentation, but
unexpectedly express both BDCA-2 and CD123, potentially
78 Unexpectedly,
expression analysis revealed that FGF15 is
79 Unexpectedly,
extreme particulate matter levels simultan
80 Here, we
unexpectedly found that inserting an enhancer containing
81 plicated separately in muscle remodeling, we
unexpectedly found that they participate in the same pat
82 We also
unexpectedly found that, over time, smaller-bodied popul
83 lammatory response in murine peritonitis and
unexpectedly found the accumulation of adrenic acid (AdA
84 provides evidence that there is
unexpectedly frequent co-transmission of related parasit
85 cate that point mutation of Rho-GAP genes is
unexpectedly frequent in several cancer types, with DLC1
86 Unexpectedly,
full-length MeCP2 protein failed to bind G
87 , we show that the mouse and fly Gsx factors
unexpectedly gain DNA binding specificity by forming coo
88 Unexpectedly,
genomic differences between sexes increase
89 Unexpectedly,
GFP-MuMx1 in Huh7 cells also associated wi
90 Unexpectedly,
Gpr27 deletion reduced expression of Eif4e
91 nhibits the thiolase activity of HADHB, but,
unexpectedly,
HADHB activates viperin, leading to synthe
92 strated that CNS myelin-specific CD8 T cells
unexpectedly harbor immune regulatory capacity in both m
93 wn plant growth-promoting rhizobacterium can
unexpectedly have either beneficial or deleterious effec
94 assays, we found that RPA binds RNA with an
unexpectedly high affinity (K(D) ~ 100 pm).
95 n that can lead to mineralized structures of
unexpectedly high complexity.
96 e breakdown in open mitosis(3), revealing an
unexpectedly high conservation of nuclear remodelling me
97 rituximab maintenance was associated with an
unexpectedly high cumulative incidence of death in remis
98 orer perceived performance during cases with
unexpectedly high difficulty (P < 0.001).
99 The
unexpectedly high estrogenic effects in many samples ind
100 hin the coastal upwelling zone, revealing an
unexpectedly high level of endemism within the Humboldt
101 In this study, we identified
unexpectedly high levels of m(5)C in the murine leukemia
102 esonances (formants) could be predicted with
unexpectedly high precision from the changing shape of t
103 The ddXR method uncovered
unexpectedly high rates of large (> 20 kb) excisions and
104 s highly conserved, as demonstrated by their
unexpectedly high sequence identity.
105 Unexpectedly,
high fat diet induced extensive atheroscle
106 ved plasmablasts during experimental malaria
unexpectedly hindered parasite control by impeding germi
107 Unexpectedly,
however, not all sequences fitting this co
108 Unexpectedly,
however, we found that extracellular Mal i
109 Unexpectedly,
HPV-specific T cell responses from OPC pat
110 transcriptomics and functional genomics, we
unexpectedly identified a nodal role for the caspase-8 p
111 In addition to T cell loci, we
unexpectedly identified myeloid- and CNS-specific risk l
112 ic map and find that these bottom-up changes
unexpectedly impair performance on an adaptive tone disc
113 icial and suggests that turnover may play an
unexpectedly important role in the decision-making proce
114 ring pattern and high EMG activity was found
unexpectedly in deep anesthesia.
115 are vector-borne RNA viruses that can emerge
unexpectedly in human populations and cause a spectrum o
116 variants were functionally neutral, perhaps
unexpectedly in light of its evolutionary conservation.
117 Unexpectedly,
in Bmal1 knockout mice, both tissues exhib
118 Unexpectedly,
in GCB cells transcription-independent reg
119 Unexpectedly,
in many cases, these expression levels dec
120 We report that,
unexpectedly,
in two different mouse xenograft models an
121 n, but high-molecular-weight beta-catenin is
unexpectedly increased by Wnt signaling.
122 ased phosphate uptake, as expected, but also
unexpectedly increased phosphate efflux, whereas PFBC-as
123 enome-wide NELF dissociation from chromatin,
unexpectedly,
independent of CDK9, a presumed NELF kinas
124 Unexpectedly,
inductive perforin-2 expression in decidua
125 Unexpectedly,
infection with respiratory syncytial virus
126 e of proteins found on the RBC surface, but,
unexpectedly,
inhibition of invasion does not correlate
127 Dorian, predicted to remain tropical storm,
unexpectedly intensified into a Category 5 storm and des
128 Unexpectedly,
jasmonic acid (JA) was not involved, as th
129 Unexpectedly,
KLK7 was dispensable for the development o
130 )(2) PbBr(4) /C(8) -BTBT channels exhibit an
unexpectedly large hysteresis window between forward and
131 on Barro Colorado Island, Panama, caused an
unexpectedly large increase in soil CO(2) emissions.
132 by abstraction of pyridine with BF(3).Et(2)O
unexpectedly led to a B/Al metathesis with the preservat
133 Unexpectedly,
LIP exhibited stronger local functional co
134 Unexpectedly,
lipogenesis was not significantly altered
135 he heart primarily consumed fatty acids and,
unexpectedly,
little glucose; secreted glutamine and oth
136 e reversal and mirror symmetries, showing an
unexpectedly long spin lifetime up to 1 ns.
137 Unexpectedly,
loss of Lem2 or its interacting partner Nu
138 is, the trial was terminated early due to an
unexpectedly low exacerbation rate.
139 ality of patients delisted for "too sick" is
unexpectedly low.
140 ndicate that local cues in the heart in vivo
unexpectedly maintain fully open chromatin in ECs at gen
141 emonstrate that HCN1, Kv1.1, PSD95 and GAD67
unexpectedly mark patterns of basket cell pinceaux that
142 motile and nonmotile P. aeruginosa However,
unexpectedly,
mechanistic studies revealed that CD18 exp
143 Unexpectedly,
mice without Asxl2 only in myeloid cells (
144 esized from brown anole and alligator, which
unexpectedly more resembles the neognathous birds.
145 LPS-stimulated cytokines was not found but,
unexpectedly,
more infectious complications occurred.
146 Unexpectedly,
mRNA and protein expression of the epithel
147 Unexpectedly,
mutating the PEP surface and the hydrophob
148 Unexpectedly,
myristoylation efficiency of MA(NOS) in Es
149 Unexpectedly,
neither the presence of membrane-associate
150 We report here that,
unexpectedly,
Nodal signaling is a major point of synerg
151 riven Cre was circulating myeloid cells but,
unexpectedly,
not microglia.
152 Unexpectedly,
nuclear expression of the EMT-TF ZEB2 in h
153 ycosylation substrates of NleB orthologs, we
unexpectedly observed that the bacterial glutathione syn
154 majority of gap junctions formed by ON CBCs
unexpectedly occur between ON CBCs, rather than with Aii
155 Unexpectedly,
on many substrates, including pre-rRNAs an
156 Unexpectedly,
one of the top 'hits' was a GSK3 inhibitor
157 Unexpectedly,
one top hit was Traf3, a negative regulato
158 Unexpectedly,
only minor antigen-mismatched grafts were
159 Unexpectedly,
our data reveal that reducing TCR signal s
160 Unexpectedly,
our data show that neither the substrate T
161 Unexpectedly,
our data support the formation of a ketoim
162 Unexpectedly,
our epigenomic experiments reveal that ZBE
163 Unexpectedly,
our studies show that the KH domains do no
164 ple and complex effects on trypanosomes, but
unexpectedly partially activates mitochondrial ATP-gener
165 ticipants completed the tasks as expected or
unexpectedly performed sedentary activities.
166 that this community and endemic species have
unexpectedly persisted in cold, high-elevation sites, ev
167 Unexpectedly,
pharmacological blockade of MORs in the SN
168 Unexpectedly,
pharmacological blockade or genetic deleti
169 Unexpectedly,
phosphorylation is not promoted by chemota
170 Unexpectedly,
plasma BMP10 levels were also markedly red
171 Unexpectedly,
Pol delta binds only one subunit of the PC
172 dies of HBV RT have been hampered due to its
unexpectedly poor solubility.
173 tic domain binds extranucleosomal DNA and is
unexpectedly positioned 100 angstrom away from the nucle
174 The genuine-quiescent state is
unexpectedly preserved into later life, succumbing only
175 g in different portions of the visual field,
unexpectedly preserving spatial information.
176 ulated by NtBRC1A-1, 1B-1, and 1B-2, but was
unexpectedly promoted by NtBRC2A.
177 Further, ovariectomy
unexpectedly promotes midlife survival of female mice la
178 Unexpectedly,
protein crystal structure analysis and mol
179 This mechanism leads to
unexpectedly rapid autoxidation even in the presence of
180 Unexpectedly,
rapid growth was also observed in intact f
181 t than men, and that increasing payment size
unexpectedly reduced effort.
182 pleting the thick filaments in one sarcomere
unexpectedly reduced force production.
183 Unexpectedly,
regarding its critical function, previous
184 The pathway
unexpectedly requires the installation and removal of an
185 365-to-alanine (S365A) mutation in STING are
unexpectedly resistant to Herpes Simplex Virus (HSV)-1,
186 rimental animals with oxidized LDL particles
unexpectedly resulted in activation of atheroprotective
187 (6)](2-) (4), and N-heterocyclic silylene 5,
unexpectedly results in synergic THF ring-opening via a
188 typic characterization of these SHP2 mutants
unexpectedly revealed a critical role of SHP2 in GI biol
189 age of four brain transcriptome studies that
unexpectedly revealed evidence of covert DWV-A infection
190 Electron tomography
unexpectedly revealed spermatocyte anaphase A does not s
191 Examination of additional point mutants
unexpectedly revealed that the CTS of Bim directly inter
192 The complex structure, however,
unexpectedly reveals that the interaction between WhiB1
193 deep sequencing-based analysis has revealed
unexpectedly rich relationships between inherited epigen
194 y via trans protein-protein interactions, is
unexpectedly rigid in free Cre.
195 Unexpectedly,
RNA, which is abundant in NETs and psoriat
196 Unexpectedly,
RNAs tended to co-sediment with other RNAs
197 for the first time that the SFO contains an
unexpectedly robust autonomous clock with unusual spatio
198 Unexpectedly,
robust RNAi-mediated depletion of TORC1 co
199 Unexpectedly,
sensitivity to loss of Ino80-mediated HR i
200 we identified a number of new residues that
unexpectedly serve to regulate transcription.
201 Unexpectedly,
SETD3 was active on the substituted methio
202 nclusion creating false PBR distinctions but
unexpectedly,
several E- and E+ accessions were distingu
203 Unexpectedly,
several of the variants produced reduced D
204 Unexpectedly,
some corals survived the event by recoveri
205 Unexpectedly,
some evolved populations and clones show a
206 Unexpectedly,
some Pelagibacterales also exhibited highe
207 in male mammals, the results demonstrate an
unexpectedly specific and deep-rooted, phylogenetically
208 t-cell compressions under external pressures
unexpectedly stabilize the disordered phases of Y(2) CoI
209 Unexpectedly,
strains of Escherichia coli expressing thi
210 tion frequency and bowel movement quality as
unexpectedly strong sources of gut microbiota variance t
211 Unexpectedly,
strong trimethylation of histone H3 at lys
212 Instead, our assay platform
unexpectedly suggests a novel mode of phenothiazine acti
213 However, blocking both GATs
unexpectedly suppressed oscillations.
214 Third, HSA
unexpectedly suppresses membrane interactions with the N
215 Unexpectedly,
sustained H3K36me3 deposition is dependent
216 resembled that used by the TCR, except that
unexpectedly,
Th1 cells employed the ITAM-bearing protei
217 We found,
unexpectedly,
that 'true S-cones' (S-opsin only) are hig
218 We found,
unexpectedly,
that HIF-1alpha-stabilizing drugs only ind
219 CLX-001 also promotes their degradation and,
unexpectedly,
that of numerous non-myristoylated BCR eff
220 rophils in infected lungs than controls, but
unexpectedly the IL-8R2-deficient mice had fewer organis
221 eurons suppressed firing of pyramidal cells,
unexpectedly the majority of interneurons also decreased
222 is activity against capsulated K. pneumoniae
Unexpectedly,
the active peptide showed no decrease in c
223 Unexpectedly,
the ALVAC-SIV/CD40L vector had a blunting
224 Finally, we show that, somewhat
unexpectedly,
the autophagy machinery is necessary for t
225 Unexpectedly,
the beetle and grasshopper odors did not b
226 Unexpectedly,
the conformation of inhibited Sec61 is opt
227 Unexpectedly,
the delta(13)C values of sulfur-containing
228 Unexpectedly,
the DNA-bound RNAP often restarts transcri
229 Unexpectedly,
the effective diffusivity of GEMs was simi
230 costimulation blockade-based approaches, but
unexpectedly,
the efficacy of costimulation blockade req
231 nd branching), reduction of the fin web, and
unexpectedly,
the evolution of asymmetry between dorsal
232 OX impairs both exocrine pancreas growth and
unexpectedly,
the generation of insulin-producing beta c
233 Unexpectedly,
the LC3-lipidation-related functions of AT
234 Unexpectedly,
the lipocalin-2 (Lcn2) gene, which encodes
235 Unexpectedly,
the majority of these coding sequence muta
236 Unexpectedly,
the mean diameter of DAT-labeled MFB axons
237 Unexpectedly,
the mice receiving WSB/EiJ microbiota incr
238 Unexpectedly,
the mRNA for GATA3 and IL-5 correlated bet
239 Unexpectedly,
the MYO10-MYO7B chimera was able to delive
240 Unexpectedly,
the open syntaxin KI partially suppresses
241 Unexpectedly,
the OTU richness of the communities after
242 Unexpectedly,
the photovoltage maps strongly correlate w
243 Unexpectedly,
the PIC alone was sufficient to reconstitu
244 Unexpectedly,
the primary host initiator of coagulation,
245 Unexpectedly,
the structure reveals one hFip1 molecule b
246 Unexpectedly,
these oligoMan-containing dendrimers, whic
247 Unexpectedly,
these prototypical pacemaker neurons expre
248 Unexpectedly,
these trials demonstrated that sodium-gluc
249 The older cohort showed an
unexpectedly thicker RNFL in the nasal sector with each
250 Unexpectedly this results in a C2 stereoisomer of mithra
251 Unexpectedly,
this approach revealed facultative incorpo
252 Unexpectedly,
this behavior is epithelial cell non-auton
253 Unexpectedly,
this complex adopts a dimeric structural a
254 Unexpectedly,
this effect was due to its ability to prom
255 Unexpectedly,
this function is not dependent on Rad53 ki
256 Unexpectedly,
this metabolic rescue is independent of in
257 Unexpectedly,
this process is driven by a decreased avai
258 Unexpectedly,
this ratio was higher in the AOM/DSS group
259 Unexpectedly,
this slow-evolving DDR is not mediated by
260 A new study describes an
unexpectedly tight relationship between dopamine activit
261 Unexpectedly,
TRA-1 also accumulates in a subset of sex-
262 Unexpectedly,
treatment of cancers having functional p53
263 Unexpectedly,
two phospholipids are bound to MlaFEDB, su
264 Unexpectedly,
unlike the inborn model, the adult-onset p
265 Thus, the proteasome provides an
unexpectedly versatile binding platform that can recogni
266 Unexpectedly we discovered that TRESK, a calcium regulat
267 Unexpectedly,
we also demonstrated that these cells indu
268 Unexpectedly,
we demonstrate that PI3Kbeta, but not PI3K
269 Unexpectedly,
we discovered that G. stearothermophilus T
270 Unexpectedly,
we find increased density of human genetic
271 Unexpectedly,
we find no signal for stochasticity when d
272 Unexpectedly,
we find that condensin is required during
273 Unexpectedly,
we find that human N-terminal glycine myri
274 Unexpectedly,
we find that PRC2 drives formation of RNA-
275 Unexpectedly,
we find that teixobactins only weakly bind
276 Unexpectedly,
we find that the suite of UNC-3 targets in
277 Unexpectedly,
we found cohesin represses minor zygotic g
278 Unexpectedly,
we found in cervical segments a population
279 Unexpectedly,
we found that 4R NM human tau (hTau) exhib
280 Unexpectedly,
we found that 5-OHBza-R is the most favore
281 Unexpectedly,
we found that AD patients presented a more
282 Unexpectedly,
we found that ALA activation promotes RIS
283 Unexpectedly,
we found that neuronal edema 48 hours afte
284 Unexpectedly,
we found that PARP1 exchanges rapidly at D
285 Unexpectedly,
we found that the central pathways of ener
286 Unexpectedly,
we found that this antibody was mischaract
287 Unexpectedly,
we found that Tim-3 was preferentially exp
288 Unexpectedly,
we found that TLR9L induced a suboptimal i
289 Unexpectedly,
we found that VHL promotes Th17 differenti
290 Unexpectedly,
we found the axon death molecule dSarm, bu
291 Unexpectedly,
we found trichostatin A to be a mutagen th
292 Unexpectedly,
we show here that, in gastrointestinal can
293 In addition, and
unexpectedly,
we show that experience is associated with
294 Unexpectedly,
we uncover a potentially generalizable act
295 Unexpectedly,
we were able to generate stable transforma
296 d its overall genetic background, indicating
unexpectedly weak correlation between morphology, geneti
297 when we studied them in the laboratory but,
unexpectedly,
were less able to induce NAbs than nonatta
298 Unexpectedly,
when overexpressing MMP14 in the early-sta
299 Unexpectedly,
when the Mgat4d gene was inactivated globa
300 Overall, expansins are
unexpectedly widespread in bacteria and eukaryotes, and