ライフサイエンスコーパス: unforeseen

1 cially when the need for venous resection is unforeseen.

2 Understanding protein folding will allow for unforeseen advances in protein design; often referred to

3 than 50 cells/microL may be associated with unforeseen adverse effects not observed in earlier studi

4 life-threatening consequences of drugs with unforeseen adverse effects on hearts, a critical evaluat

5 rated a cautionary note of the potential for unforeseen adverse effects that challenge drug developme

6 development while avoiding the occurrence of unforeseen adverse events.

7 ved supplemental EBRT (excluding a boost) if unforeseen adverse features were detected on final patho

8 technology and medicine, could also lead to unforeseen adverse health effects in exposed human subje

9 ve mutations can exert their effects through unforeseen and complex interactions.

10 emingly intuitive inhibitors may function by unforeseen and complex structural processes.

11 Thus, an unforeseen and druggable EP2 receptor in Schwann cells,

12 y are already changing mental health care in unforeseen and exciting ways, each accompanied by an ear

13 s and processes, but also the possibility of unforeseen and negative consequences upon ENM release in

14 be subject to arbitrary decision-making with unforeseen and negative ramifications.

15 COVID-19, essential workers are plagued with unforeseen and obfuscated challenges.

16 continues to fascinate, being spurred on by unforeseen and often spectacular experimental observatio

17 val of dams and reservoirs may seem to be an unforeseen and sometimes controversial step in water man

18 itous threat to aquatic ecosystems, may have unforeseen and unpredictable effects on ecosystem struct

19 arithmetic Coxeter groups, and each may have unforeseen applications to arithmetic.

20 atial transcriptomics studies have dissected unforeseen aspects depicting the immense heterogeneity o

21 f study and consistently revealed previously unforeseen avenues of clinical therapies.

22 el genome segregation machines that point to unforeseen bacterial and eukaryotic connections.

23 This unforeseen behavior indicates that the SOA is dominated

24 le for some genes, while others displayed an unforeseen behavior, confirming the high variability of

25 mission-critical to discover knowledge about unforeseen behavior.

26 ligand-bound TRPM8 structures have uncovered unforeseen binding sites for both cooling agonists and m

27 mentally observed response and help identify unforeseen biochemical events.

28 edicted by pre-clinical safety testing, were unforeseen biological effects in man.

29 In order to explore the possibility that unforeseen biological processes may be involved in the r

30 he potential to allow for the elucidation of unforeseen, biologically significant associations betwee

31 igand specificity and uncovered surprisingly unforeseen biosynthetic capacity.

32 the motivational state and may develop from unforeseen brain circuits.SIGNIFICANCE STATEMENT Actions

33 ce gains for different AI tasks are prone to unforeseen bursts.

34 rimentally that the solvent plays a hitherto unforeseen but crucial role in interparticle interaction

35 ced by a unique buffer formulation, provides unforeseen capabilities for testing, and sharing, comple

36 rm capacitation and shed light on a hitherto unforeseen cause of infertility in men.

37 An unforeseen challenge, the COVID-19 pandemic, strained al

38 pair in clinically relevant cells, we reveal unforeseen challenges and opportunities for precise ther

39 also providing tools to meet both known and unforeseen challenges facing humanity.

40 to the clinical arena uncovered a number of unforeseen challenges, mainly in the form of a human-spe

41 of-domain knowledge and cannot adapt to new, unforeseen challenges.

42 framework is unifying and adaptive to future unforeseen challenges.

43 culture to PDMS based devices can come with unforeseen challenges.

44 These unforeseen changes in chemistry resulted in a roughly 25

45 These peak periods were primarily driven by unforeseen changes in conditions within one day of opera

46 We have, of course, made mistakes, causing unforeseen changes in ecosystem attributes, while leavin

47 Importantly, this identified unforeseen changes in the glycan shield of Env obtained

48 rotein engineer for the design of previously unforeseen coiled-coil based assemblies.

49 m, and provides the rationale for previously unforeseen combination therapies incorporating CD73 inhi

50 wolf (Canis lupus) to make an impressive and unforeseen comeback across Central Europe in recent year

51 mmune surveillance against aspergillosis, an unforeseen complication of BTK inhibitors (BTKi) used fo

52 as the process enabling organisms to survive unforeseen conditions.

53 An unforeseen consequence of poorer matching could be incre

54 ejection is a desired outcome rather than an unforeseen consequence.

55 efore introducing major initiatives to avoid unforeseen consequences and disagreements.

56 ng ligands to molecules can have drastic and unforeseen consequences in the final products of a react

57 s between land use and chemical use may have unforeseen consequences on ecosystems.

58 However they may also have unforeseen consequences, in some cases placing further d

59 e guidelines has led to several problems and unforeseen consequences.

60 do things and the possibility that there are unforeseen consequences.

61 on-target editing outcomes with potentially unforeseen consequences.

62 ransporters at the same membrane, often with unforeseen consequences.

63 re of the areas that the fish move into with unforeseen consequences.

64 re to appreciate its limitations can lead to unforeseen consequences.

65 e transporter populations are likely to have unforeseen consequences.

66 These results suggest an unforeseen conservation in mechanisms producing cell pol

67 ikingly similar architecture and unveiled an unforeseen conservation of the unique mechanism of seque

68 s implies that parasite extinctions may have unforeseen costs that impact the health and abundance of

69 ion with a 24/7 ICU consult service may have unforeseen costs without obvious benefit.

70 COVID-19 vaccines demonstrated, meeting the unforeseen crisis of the uncertain future requires conti

71 conservation of these proteins often lead to unforeseen cross reactivity, yielding unexpected side ef

72 ously detect and localize different types of unforeseen damage.

73 together with biochemical analysis, provide unforeseen details about how NMT1 reaches a catalyticall

74 perating room, but this reduction could have unforeseen detrimental effects in terms of postoperative

75 Electrical impedance assessment revealed unforeseen detrimental effects of UV-A, beginning at 350

76 However, we also noted unforeseen differences in implementation that seemed to

77 r approach allowed us to quantify previously unforeseen differences in vesicle dynamics, transferrin

78 has many benefits, this practice can lead to unforeseen difficulties in doctor-patient communication

79 gh frequency of novel mutations, has created unforeseen difficulties in translating complex science (

80 very and settlement of the Americas revealed unforeseen dimensions and gave rise to unpremeditated wa

81 er review might shift scientific activity in unforeseen directions.

82 ional and morphological timelines, revealing unforeseen diversity in mammalian developmental sequence

83 ing from 2 to 22 months establish previously unforeseen dynamic changes in L1 mRNA expression in vivo

84 g efforts is essential for addressing future unforeseen ecological issues.

85 ly to entail major opportunity costs or pose unforeseen economic risks to households.

86 to similar unexpected "recoveries" involving unforeseen ecosystem effects, such as the return of hake

87 e study was underpowered to demonstrate this unforeseen effect (P=0.1995).

88 This unforeseen effect should be considered in the ongoing de

89 biota or S-nitrosylation in ALG-1, we reveal unforeseen effects on host development.

90 bstances are likely to have adverse, perhaps unforeseen effects, especially with long-term preventive

91 efore be identified early on to mitigate any unforeseen effects.

92 environmental regulations have often led to unforeseen emission changes.

93 g that some cells are always prepared for an unforeseen environmental fluctuation.

94 lation has been the main control strategy of unforeseen epidemic outbreaks.

95 Such unforeseen epitope generation warrants careful analysis

96 lopathy (BSE) prions were responsible for an unforeseen epizootic in cattle which had a vast social,

97 redicting Intensive Care Transfers and other UnfoReseen Events (PICTURE), a deterioration index devel

98 differentiate and discover that they display unforeseen evolutionary trajectories: cells first exhibi

99 To avoid unforeseen explosions, remotely controlled "blast-in-pla

100 Our studies reveal an unforeseen extranuclear function for Ezh2 in regulating

101 NA synthesis (TLS), these findings unveil an unforeseen facet of the regulation by Chk1 of DNA replic

102 Here, we report an ATM-kinase dependent, unforeseen function of the nuclear isoform of the Recept

103 al a new mechanism of fate regulation and an unforeseen functional capability of HSCs.

104 d moderate hesitancy, mainly concerned about unforeseen future effects; Profile C - Hesitant with Mis

105 scRNA-seq demonstrated an unforeseen gene expression heterogeneity among macrophag

106 water content(13), and reducing the risk of unforeseen ground conditions in the construction of crit

107 plication rates were high and included three unforeseen hazardous intravascular thrombotic complicati

108 improving their functionality and minimizing unforeseen health/environmental hazards.

109 However, unforeseen heart complications, especially a rapid devel

110 Thus, targeted molecular analyses reveal an unforeseen heterogeneity in D2R-expressing striatal neur

111 population genetic studies have revealed an unforeseen hidden diversity of cryptic species among mic

112 in natural plant populations can bring about unforeseen impacts that may negatively affect fitness.

113 rventions in context, describe predicted and unforeseen impacts, assess potential for generalisabilit

114 Recent findings are revealing the profound, unforeseen implications of such characteristics for the

115 nd negatively correlate with MgO/CaO ratios, unforeseen in sedimentary carbonates.

116 We find enhanced potency stems from an unforeseen increase in siRNA loading to the RNA-induced

117 gh only enhanced crop fertilization may have unforeseen, indirect, effects on crop susceptibility to

118 r (ii) exchange is indeed obligatory, but an unforeseen initial concentration of amino acid substrate

119 tumour entities but also because it provides unforeseen insights into the metabolic adaptation that t

120 nchors Ent1 to a stable endocytic coat by an unforeseen interaction between Sla2's ANTH and Ent1's EN

121 for neuroprotection by a highly specific and unforeseen interaction between the CaMKIIa hub domain an

122 ver, changes in environmental conditions and unforeseen interactions with the host cell can cause dev

123 main after illumination suggest formation of unforeseen intermediate states prior to tetramer dissoci

124 Our results reveal an unforeseen interplay between lipid biosynthesis and memb

125 the 5' end of RNA has uncovered a previously unforeseen intersection between cellular metabolism and

126 d to the identification of several known and unforeseen key transcriptional events occurring during B

127 These findings uncover an unforeseen level of specificity in the role of motor pro

128 an important human pathogen and provide many unforeseen lines of pathogenesis investigation.

129 These hematopoietic defects underscore an unforeseen link between hypertrophic cartilage, endochon

130 an atom-transfer radical cyclization and an unforeseen lithium-halogen exchange with n-BuLi.

131 ur and plant response will lead to currently unforeseen losses in rice grain productivity and quality

132 zing the OFF state of the myosin heads in an unforeseen manner.

133 -1 led to decreased lung-associated TFPI and unforeseen massive fibrin deposition.

134 Our data identify an unforeseen mechanism linking copper, redox homeostasis,

135 Our work describes an unforeseen mechanism of action for rapamycin that sugges

136 se findings describe a specific, potent, and unforeseen mechanism of action of ribavirin.

137 quaternary structures represent an important unforeseen mechanism of receptor biased signaling and re

138 Here, we report an unforeseen mechanism that regulates mitochondrial divisi

139 d protein structure prediction, we deduce an unforeseen mechanism whereby the polyamine and H(+) comp

140 ive has led to the recognition of previously unforeseen mechanisms for altering climate.

141 urdened by unexpected continence challenges, unforeseen menstrual changes, devastation of having huma

142 nd the pentose phosphate pathways to form an unforeseen metabolic architecture (EDEMP cycle).

143 These findings reveal an unforeseen metabolic function for phospholipid and histo

144 ates the composition of human plasma reveals unforeseen metabolic wiring and regulation, suggesting t

145 We uncover unforeseen modes of allelic expression that appear to be

146 Unforeseen modification of drugs by the microbiome can d

147 ruptions interact with anthropogenic warming unforeseen multiplier effects may occur.

148 bustness in predicting mutation patterns for unforeseen mutations, we first designed a synthetic case

149 P(noninferior) < .0250) was the presence of unforeseen N2 disease after tumor resection with lymph n

150 Unforeseen N2 rate after immediate resection (8.8%) was

151 chosen noninferiority margin in the rate of unforeseen N2, confirmatory mediastinoscopy after negati

152 d noninferiority trial to determine rates of unforeseen nodal metastases after EBUS alone versus EBUS

153 s to ride a bicycle in the driveway, free of unforeseen obstacles.

154 aking without succumbing to distractions and unforeseen obstacles.

155 Unforeseen opportunism and geographical expansion by inv

156 dogenous hormone-like CB2 receptor PAM, with unforeseen opposite allosteric effects on cannabinoid re

157 An unforeseen original class of stable N-heterocyclic carbe

158 nges associated with disease management, the unforeseen overlap of the study with the pandemic elevat

159 er bnAbs, we anticipate that protection from unforeseen pandemic influenza A viruses is achievable.

160 bernate underground in tropical forests draw unforeseen parallels to mammalian temperate hibernation.

161 Here we report the unforeseen participation of Caenorhabditis elegans TIM-1

162 ent with a MB-cell origin and delineating an unforeseen pathway for malignant transformation of the i

163 cognitive systems (ACS) to quickly adapt to unforeseen perceptual anomalies generated by the environ

164 These unforeseen phenomena may be critical for improving our f

165 Overall, these findings reveal unforeseen phosphorylation complexity, thereby increasin

166 rge ordered La(1.75)Sr(0.25)NiO(4) to reveal unforeseen photoinduced phase fluctuations of the charge

167 with random exchange interactions exhibiting unforeseen physical properties.

168 We recently discovered however, an unforeseen polymorph of coronene, which exists as an ena

169 al vaccination with a leaky vaccine can have unforeseen positive consequences in controlling the spre

170 ocessive growth at both ends, which suggests unforeseen possibilities for cellular actin organization

171 This opens unforeseen possibilities for the development of novel me

172 Our proposal, which highlights previously unforeseen possibilities for the synergistic exploitatio

173 tion at 1 year because of the development of unforeseen post-LT complications.

174 Our findings suggest a hitherto unforeseen potential of nonnative structure to induce si

175 Here, we identify an unforeseen principle by which a GDP-bound form of the co

176 ecent half-century, to continue illuminating unforeseen processes and patterns in microorganisms, the

177 opriate antibiotic prescription leads to the unforeseen production of drug-resistant bacteria.

178 -3-3 isoforms, which collectively display an unforeseen pT205/pS197 peptide binding selectivity hiera

179 C-tier polarity of translocation reveals an unforeseen quality-control mechanism at the origin.

180 Here we report an unforeseen reaction discovered during the investigation

181 le models can be used to unravel additional, unforeseen reactions.

182 We report an unforeseen reactivity mode for productive photocatalysis

183 demonstrated, providing direct insights into unforeseen rearrangements of the metal center during cat

184 f high-risk genes associated with ALS and an unforeseen reduction of chromatin accessibility in MNs.

185 Our data suggest an unforeseen relationship between epithelial mesenchymal p

186 nity but also in neurotrophism, revealing an unforeseen relationship between the neurotrophin and Tol

187 emodeling complex (Ino80C), thus defining an unforeseen relationship between these two machineries.

188 romone blends in flight tunnel bioassays, an unforeseen result counter to the assumption that a donor

189 These unforeseen results imply that most of the studies, if no

190 rious danger to children through exposure to unforeseen risk as a result of lack of pediatric trials

191 Our data suggest an unforeseen role for a RasGEF, and therefore presumably a

192 w of KHNYN antiviral activity and suggest an unforeseen role for activation by manganese ions in the

193 This work reveals an unforeseen role for alpha-secretase in generating an end

194 nopus embryological studies demonstrating an unforeseen role for the DAN family protein Cerberus with

195 ed that the PspC cytoplasmic domain plays an unforeseen role in negatively regulating psp gene expres

196 Thus, capsid may play an unforeseen role in these previously observed G3BP-positi

197 Thus, our study uncovers an unforeseen role of CaN in postsynaptic signaling, and de

198 This study unveils the pivotal yet unforeseen role of China's intertidal mariculture in sus

199 Altogether, these data establish an unforeseen role of GLS2 in sustaining tumor proliferatio

200 ly active regions of the nucleus suggests an unforeseen role of RGS10 in modulating gene expression.

201 The electride band, with its unforeseen role, bears kinship to the interlayer band in

202 diates allergic lung pathology and highlight unforeseen roles for the type II IL-4R.

203 with RNA binding and splicing assays reveal unforeseen roles for U2AF(65) inter-domain residues in r

204 Our data provide unforeseen roles of G-protein-coupled receptor kinase 2

205 endent evolution can be engineered to access unforeseen routes of improving metabolic pathways and pr

206 These findings reveal an unforeseen safeguard mechanism that prevents extreme fus

207 es the capture of operative video data on an unforeseen scale.

208 dic devices in reaction to specific needs or unforeseen scenarios.

209 nalog-PUF structure may lead to a variety of unforeseen securities and anti-counterfeiting applicatio

210 gree of allosteric modulation, indicating an unforeseen selectivity of membrane proteins toward the c

211 tes coughing but not sneezing, unraveling an unforeseen sensory difference between sneezing and cough

212 analyses show that there is an intricate and unforeseen set of interactions controlling allosteric co

213 plications regarding optimal performance and unforeseen side effects following device implantation in

214 ations, to address concerns over toxicity or unforeseen side effects.

215 odels often lack stability and may introduce unforeseen side effects.

216 stable and active variant crystallized in an unforeseen signalling-active conformation, in excellent

217 In unforeseen situations, such as nuclear power plant's or

218 This may constitute a previously unforeseen source of genetic diversity contributing to t

219 ting data illustrate how a ferryl iron, with unforeseen stability, may be achieved in biology.

220 lly canceled arm movements in response to an unforeseen stop signal, the LFP power, particularly in a

221 s simulations, we show that HOSO displays an unforeseen strong acidity (pK(a) = -1) comparable with t

222 alysis of the VosA velvet domain revealed an unforeseen structural similarity with the Rel homology d

223 of theories of polymer elasticity, revealed unforeseen structural transitions induced by mechanical

224 Unforeseen synthetic challenges are reported such as the

225 r results also identify ClpXP activity as an unforeseen target for therapeutic interventions in the l

226 he catalytic core and include two previously unforeseen (to our knowledge) tertiary interactions.

227 Recent studies have revealed an unforeseen toxicity of TRAIL toward normal human hepatoc

228 rituximab in combination with CHOP, may have unforeseen toxicity.

229 thers have shown negligible efficacy or even unforeseen toxicity.

230 inal, dermal, and anal glands, are revealing unforeseen trophic relationships with biological control

231 Our work unveils an unforeseen tumor-suppressing role for mTORC2 in the earl

232 aterials results in lamellar structures with unforeseen uniformity in the domain spacing.

233 these observations uncover time-of-day as an unforeseen variable for cancer immunotherapy responses.

234 Together, these two discoveries suggest that unforeseen variation in isoprenoid metabolism may be wid

235 blood spot samples from day 0 and day 28 (or unforeseen visit) and analysed them by quantitative PCR

236 Day 28 (or unforeseen visit) samples positive for non-falciparum ma

237 Unforeseen was the finding that 30%-40% of unaligned rea

238 Also unforeseen was the inhibitors' mechanism of action again

239 eling and experiment, we show that there are unforeseen ways in which widely used reporter strategies