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1 mnestic-type, amnestic/non-amnestic-type and unimpaired).
2 lammatory response to ovalbumin and alum was unimpaired.
3 1.21), while other subgroups are effectively unimpaired.
4 r symptoms, many patients remain cognitively unimpaired.
5 +)CD25- T cells leaving CD4(+)CD25(hi) Tregs unimpaired.
6 r puff-predictive cues or air puff, remained unimpaired.
7 although many aspects of visual function are unimpaired.
8 er low ssb transcript levels where growth is unimpaired.
9 ndefinitely and immunity to foreign antigens unimpaired.
10 he costimulatory molecules CD40 and CD86 was unimpaired.
11 functionality of the protein part remaining unimpaired.
12 itial T cell homing to pancreatic islets was unimpaired.
13 hematopoietic stem and progenitor cells was unimpaired.
14 or cell expansion or granulopoiesis remained unimpaired.
15 cisions that were not context-dependent were unimpaired.
16 time points while the binding of zymosan was unimpaired.
17 d normally only when the olfactory system is unimpaired.
18 pecific, IFN-gamma-producing CD8 T cells was unimpaired.
19 soluble lysosomal protease trypanopain, were unimpaired.
20 showing that face identification per se was unimpaired.
21 recognition and adhesion of these cells are unimpaired.
22 ing that neuregulin signaling from axons was unimpaired.
23 ons, but functions after GM-CSF priming were unimpaired.
24 ophage differentiation and function remained unimpaired.
25 of interleukin 6 or the chemokine MCP-1 was unimpaired.
26 or in proximity to the relevant epitopes was unimpaired.
27 ts T-cell responses but leaves DC activation unimpaired.
28 onth-old, prepathologic mice are cognitively unimpaired.
29 Negative selection was unimpaired.
30 and spreading on immobilized fibrinogen are unimpaired.
31 system pathology does in fact leave the SRT unimpaired.
32 with those patients who were not cognitively unimpaired.
33 oconstrictors, and relaxation responses were unimpaired.
34 since their ability to run, swim and grip is unimpaired.
35 ng, and transsynaptic nano-organization were unimpaired.
36 le PV bistratified and axo-axonic cells were unimpaired.
37 espiratory chain function in those cells was unimpaired.
38 s among individuals who remained cognitively unimpaired.
39 nd Extinction learning tasks was found to be unimpaired.
40 impairment (SIS score <5 [impaired] vs >/=5 [unimpaired]).
41 to either amyloid-beta-negative cognitively unimpaired (0.4 +/- 2.7%), amyloid-beta-negative mild co
43 articipants >= 80 years old (357 cognitively unimpaired, 118 cognitively impaired at baseline, mean a
45 and Dementia [TRIAD, n = 116; 74 cognitively unimpaired, 42 cognitively impaired (MCI n = 16, Alzheim
46 duction in amyloid-beta-positive cognitively unimpaired (71 participants per arm in amyloid-beta-posi
47 two cohorts: ADNI [n = 198; 110 cognitively unimpaired, 88 cognitively impaired (MCI n = 67, Alzheim
48 d elevated beta-D-galactosylsphingosine with unimpaired activity of cognate lysosomal hydrolases.
49 profiles required for proper development and unimpaired adulthood, and comprise the components of the
50 nute familiarisation period, suggesting that unimpaired adults either are unable to, or do not need t
51 earning of a body-machine interface in young unimpaired adults, two groups of typically developing ch
52 activity of chNKG2D-bearing T cells remained unimpaired after exposure to a soluble NKG2D ligand, sol
54 rats (24 months old) were divided into aged-unimpaired and aged-impaired groups based on comparison
59 al clearance and SP-D/SP-A upregulation were unimpaired and so were early virus-induced cytokine and
60 were specific to amyloid PET in cognitively unimpaired and tau PET in cognitively impaired (P < 0.05
61 itions, RagA-deficient HSC were functionally unimpaired and upregulated mTORC1 via nutrient-insensiti
63 ns male rats into young adult, aged learning-unimpaired, and equally aged learning-impaired groups.
64 rm regenerative potential of hepatocytes was unimpaired, and growth of aggressive experimental hepato
65 tively unimpaired, Ptau positive cognitively unimpaired, and Ptau positive individuals with mild cogn
66 cytoid dendritic cells (pDCs) to the CNS was unimpaired, and the presence of pDCs was found to be an
67 cells into IL-4-secreting effector cells was unimpaired, and under certain conditions DO11.10(+) Fyn-
72 avoid familiar items) but were subsequently unimpaired at acquiring new constant negative problems,
74 DNA concatemers into unit-length genomes was unimpaired at either a low or high multiplicity of infec
75 ions of both past and future events but were unimpaired at producing detailed picture narratives.
77 Aged rats were separated into cognitively unimpaired (AU) or impaired (AI) groups based on their M
79 ent when compared to the young animals (aged-unimpaired; "AU") and one in which performance was signi
80 ent mice display normal cold sensitivity and unimpaired auditory function, suggesting that this chann
84 cells, present in normal numbers, exhibited unimpaired BCR-induced spleen tyrosine kinase (Syk) phos
85 IL-2, conventional T-cell responses proceed unimpaired because IL-21 can substitute for IL-2 as a T
86 ompared to amyloid-beta-negative cognitively unimpaired (beta = 0.56, P < 0.001, using linear mixed e
87 human patients, Atp8b1(G308V/G308V) mice had unimpaired bile secretion and no liver damage, but showe
89 participants, 92% (441/480) were cognitively unimpaired but the A+T+(N)+ group had the largest propor
90 l hydrophilic domain left transport function unimpaired, but deletion of the adjacent STAS (sulfate t
92 early stages of fertilization are evidently unimpaired, but most embryos from Zar1(-/-) females arre
95 Both CD4(+) and CD8(+) T-cell activation was unimpaired by B-cell deficiency, and delayed disease was
96 is to conditionally active oncogenic Ras was unimpaired by deletion of either Mek1 or Mek2 MAPKKs ind
97 Progeny production of parvoviruses was also unimpaired by IFN in both glioma and melanoma, whereas v
100 ediamine in place of ubiquinol was, however, unimpaired by the mutations, indicating that the catalyt
101 ry to prediction, tutor song memorization is unimpaired by unilateral estrogen synthesis blockade in
104 ation of cytosolic proteasome substrates and unimpaired clearance of stress-induced protein aggregate
106 de significant locus among participants with unimpaired cognition on chromosome 18 upstream of ATP8B1
107 d restricting the sample to individuals with unimpaired cognition to identify variants at the earlies
108 bin concentration and impaired compared with unimpaired cognitive function were 2.1 (95% CI: 1.1, 3.7
110 Initiative [ADNI: n = 1149; 382 cognitively unimpaired control subjects and 767 cognitively impaired
112 comparable replication kinetics, we observed unimpaired coreplication of both viruses, generated suit
113 arison of this map with one derived from the unimpaired counterparts indicated a specific lesion "hot
114 ing Initiative (ADNI), including cognitively unimpaired (CU), mild cognitive impairment (MCI) and AD
116 , CatS(-/-) traditional stage 1 B cells show unimpaired degradation of endocytic cargo, have intact B
117 cell- and B cell-deficient Rag1-/- mice was unimpaired, demonstrating that adaptive immune cells are
118 rmed before sexual maturation, attraction is unimpaired, demonstrating that these neurons compensate
119 s allow these patients to remain cognitively unimpaired despite substantial dopamine dysregulation.
120 Infection of Tbx21(-/-) mice led to normal, unimpaired development of Ag-specific CD4(+) T cells pro
122 ns is a prerequisite to ensure immune cells' unimpaired differentiation, maturation, and selection, a
123 uch as the water maze, GluR-A(-/-) mice were unimpaired during acquisition of the spatial discriminat
124 ividuals [young adults (n = 22), cognitively unimpaired elderly (n = 89), and cognitively impaired (n
126 ed on clinical classification of cognitively unimpaired elderly versus Alzheimer disease dementia, RO
127 In contrast, high-P cells were functionally unimpaired, eliminating chronic provision of saturating
128 However, the lack of streamflow data or unimpaired flow scenarios makes it difficult to model TO
130 ethods Between 2011 and 2013, 61 cognitively unimpaired former collegiate and professional football p
132 hamide-treated mice, and was associated with unimpaired fungal growth in the cornea, and with hyphae
133 er, we also evaluated subgroups dividing the unimpaired group by normal/abnormal amyloid PET and the
137 eta*56 levels increased with age; within the unimpaired group, they were elevated in subjects with T-
138 e cognitive differences between impaired and unimpaired groups can be detected years before a diagnos
140 s increased in those impaired (compared with unimpaired hypertensive individuals: HR=1.10, 95% confid
142 mmasome-mediated IL-1beta maturation, showed unimpaired IL-1beta production and importantly, were con
147 ment into the proximity of nursery cells was unimpaired in APRIL-deficient mice, questioning the conc
148 migration to the embryonic gonadal ridge is unimpaired in brca2(Q658X) homozygotes; thus, failure of
149 Parasite dissemination to the brain was unimpaired in CD73(-/-) hosts, suggesting that the reduc
150 Notably, heparanase enzymatic activity was unimpaired in cells overexpressing Hpa2, suggesting that
151 n a T-maze procedural learning task but were unimpaired in cognitive function and behavioral flexibil
154 oration into glycerophosphocholine lipids is unimpaired in iPLA(2)beta-null macrophages upon electros
155 wth and morphology of the dacA-1 mutant were unimpaired in LB media containing reduced concentrations
157 spensable; a deletion mutant (Deltaacr2) was unimpaired in log phase growth and persisted in IFN-gamm
158 by intracellular Salmonella or Listeria was unimpaired in macrophages deficient in P2X7 receptor.
159 MDP uptake and NOD2-dependent signaling were unimpaired in macrophages deficient in PepT1, a peptide
160 activity in response to CD40 stimulation was unimpaired in macrophages from IFN-gamma(-/-) mice, macr
165 nctions dependent on integrin activation are unimpaired in mice lacking the Rap1-GTP-interacting adap
171 nergic input to prefrontal cortex (PFC) were unimpaired in tests of decision making and episodic memo
174 resilient individuals to remain cognitively unimpaired in the face of substantial neuropathology.
177 beta(3) and beta(5) integrins were similarly unimpaired in their ability to cross-present OVA-bearing
178 e show that BH-deficient cells from mice are unimpaired in their ability to present epitopes from N-e
179 hat, despite this, histone H3 acetylation is unimpaired in these cells and that IE genes can be induc
183 These results provide novel evidence of unimpaired in vivo glycolytic function in the skeletal m
186 hypothesis that schizophrenia patients have unimpaired in-the-moment emotional reactivity but have a
187 ; however, ICP27 export to the cytoplasm was unimpaired, indicating that the interaction of ICP27 wit
189 1.01 x 10-3]) and in cognitively impaired vs unimpaired individuals (count: 21 [0-99] vs 13 [1-54]; v
195 pairment (MCI) or dementia among cognitively unimpaired individuals by APOE-e4 dose for the genetic d
196 bles, our results indicate that screening of unimpaired individuals for potential inclusion in anti-t
197 ading to an increasing number of cognitively unimpaired individuals, who are concerned that they have
199 ng Ras(V12) continued to proliferate despite unimpaired induction of p19ARF and p53, and lacked morph
200 f p53 by the Hdm2 antagonist Nutlin-3 led to unimpaired induction of p53 target genes as well as grow
201 However, the Arp2/3-deficient cells exhibit unimpaired lamellipodial actin network structure, transl
202 s restricting comparisons to the cognitively unimpaired LLD participants as well as when comparing th
203 ion cohort (n = 39) of initially cognitively unimpaired, longitudinally assessed older-adult brain do
207 s to de novo antigenic challenges as well as unimpaired memory T cell responses to viral rechallenge.
208 curacy on an equivalent memory task remained unimpaired (meta-d'/d', 95% confidence interval 0.78-1.2
209 nt to IFN-alpha/beta action, as indicated by unimpaired MHV replication in L2 cells pretreated with I
211 five clinical diagnostic groups: cognitively unimpaired, mild cognitive impairment, frontotemporal de
212 lformation, and chondrodysplasia, but showed unimpaired mineralization in primary and secondary encho
213 anged neurocognitive status from impaired to unimpaired (monotherapy, 4 of 18 [22.2%]; triple therapy
214 EM sleep behavior disorder (RBD) show mostly unimpaired motor behavior during REM sleep, which contra
217 The study participants were cognitively unimpaired (n = 153), or patients with mild cognitive im
218 two clinical diagnostic groups: cognitively unimpaired (n = 203); or cognitively impaired (n = 134,
219 eclinical (amyloid-beta-positive cognitively unimpaired, n = 62) and prodromal (amyloid-beta-positive
221 secretory vesicles to the plasma membrane is unimpaired, none of the exocyst subunits are polarized.
222 from young adults (AUC=100%) and cognitively unimpaired older adults (AUC=84.44%), but not from MCI (
223 ve young adults (AUC=99.40%) and cognitively unimpaired older adults (AUC=90.21-98.24% across cohorts
224 (TRIAD and BioFINDER-2) included cognitively unimpaired older adults (mean age 63-69 years), particip
225 ons in the amyloid beta-positive cognitively unimpaired older adults and MCI groups, to the highest c
226 d beta-negative young adults and cognitively unimpaired older adults, through higher concentrations i
228 ampus (21% tissue damage) yielded relatively unimpaired olfactory retention across brief (30 s), inte
229 ior thalamic lesions and fornix lesions were unimpaired on a configural learning task in which the ra
230 ats with perirhinal cortex lesions were also unimpaired on a test of spatial working memory (reinforc
232 tests of olfactory ability, GAL-tg mice were unimpaired on buried-food and habituation-dishabituation
233 of contextual fear learning and consistently unimpaired on spatial learning in the Morris water maze.
236 tudy who were classified as neurocognitively unimpaired or with various degrees of HIV-associated neu
239 R-2 cohort (cohort 2), including cognitively unimpaired participants (n = 301) and clinically diagnos
241 al of 589 individuals, including cognitively unimpaired participants and patients with mild cognitive
242 study and 119 nondepressed (ND) cognitively unimpaired participants matched on age, sex, and APOE ge
243 r stratified groups in initially cognitively unimpaired participants sampled from the Wisconsin Regis
251 ed elderly individuals (n = 19), cognitively unimpaired patients with PD (n = 19), and patients with
252 o compare groups of cognitively impaired and unimpaired patients, matched on all other clinical measu
255 elational encoding conditions and relatively unimpaired performance under item-specific encoding cond
256 en transgenic and wild-type mice, supporting unimpaired peripheral and CNS immune responses in transg
257 row-derived macrophages (BMDMs) demonstrated unimpaired phagocytosis of MSU crystals but reduced p38
260 indicated that LRG-47-deficient mice exhibit unimpaired proinflammatory responses throughout the infe
261 on-matched groups: Ptau negative cognitively unimpaired, Ptau positive cognitively unimpaired, and Pt
266 Patients attended during encoding and had unimpaired reaction times and normal response biases dur
267 ment had substantially higher ACGL risk than unimpaired recipients (5-year ACGL: 45.5% vs 10.6%; P <
272 ponses to Nod1 and Nod2 agonists but exhibit unimpaired responses to synthetic and highly purified TL
273 phase transition, while cell growth remained unimpaired, resulting in a marked reduction in organ siz
280 ates of cognitive decline in the cognitively unimpaired subgroup with abnormal amyloid PET (P = 0.03)
282 tochondrial cytochrome c oxidase activity is unimpaired, suggesting a mode of glycolytic reprogrammin
283 KO mice to another l-amino acid, lysine, was unimpaired, suggesting that some l-amino acids can be de
286 yV-specific CD8(+) T cells were functionally unimpaired; they retained the potential for robust expan
287 limited by stay chords, the midportion moves unimpaired toward the septum, like a sail, between the 2
288 REK-1 expression on alveolar macrophages and unimpaired tumor necrosis factor-alpha secretion from TR
289 re fully viable probably because suckling is unimpaired, unlike mutants in which the expression of al
292 n a uORF-harboring stem-loop 4 structure, an unimpaired virus with wild-type (WT) growth kinetics was
293 eceiving atypical antipsychotic drugs showed unimpaired visual contrast detection, those given typica
294 ume loss; grey matter atrophy in cognitively unimpaired was specific to APOE epsilon4 carriers (P < 0
295 s at study entry (when all participants were unimpaired) were highly predictive of future cognitive d
296 C activation and migration induced by LPS is unimpaired when radioresistant cells cannot respond to t
297 NA, and unlike cap-driven translation, it is unimpaired when the 5' end is blocked by a strong hairpi
298 nfirming previous results, group IT x FC was unimpaired, whereas group TS+AM+FX was severely impaired
300 of visual motion through a cloud of dots was unimpaired without noise, the addition of stimulus noise