ライフサイエンスコーパス: unique

1 k at what makes hERG intriguing and vexingly unique.

2 We designed and demonstrated the unique abilities of the first gas chromatography-molecul

3 eals that multiple factors contribute to the unique ability of a gp41 CT truncation mutant to spread

4 polysaccharide monooxygenases (LPMOs) have a unique ability to activate molecular oxygen for subseque

5 n that the EBV type 2 (EBV-2) strain has the unique ability to infect mature T cells.

6 8,476 genome-wide SNPs, of which 194,709 are unique across 18 high-quality isolates.

7 th a highly unusual body plan and a range of unique adaptations to their environment.

8 rchitectures(7,8) and are, to our knowledge, unique among designed systems(9-13) in that they possess

9 ZBP1 is unique among innate immune sensors because of its N-term

10 immune system.(1)(,)(2) However, humans are unique among primates in that we consume highly digestib

11 ings at the level of the ring sinus revealed unique anatomical features that may promote these differ

12 electronic and vibrational domains offers a unique and complementary means to probe these polymers,

13 Our results reveal a unique and early role for NR4A3 in programming CD8(+) T

14 data-driven evolution of these procedures is unique and has led to improved vector delivery.

15 Indicator displacement assays (IDAs) offer a unique and innovative approach to molecular sensing.

16 review provides a summary description of the unique and overlapping clinical characteristics and phys

17 sequently, half of apicomplexan proteins are unique and uncharacterized.

18 Our study provides a unique and valuable resource for the fields of virology,

19 The unique and versatile reactivity of nickel enables the ol

20 nal inorganic semiconductors, which offers a unique application of organic photovoltaics (OPVs): semi

21 Sweden has taken a unique approach of not implementing strict closures, ins

22 is high-level organization confers to ASFV a unique architecture among the NCLDVs that likely reflect

23 ted by changing the electronegativity of the unique aspartate ligand.

24 ternative protein isoforms can contribute to unique aspects of brain development and function.

25 ted through cycles of glaciation, leading to unique assemblages in polar waters, rather than being en

26 substantial difficulty in disentangling the unique associations with statewide restrictions on inter

27 e restrictions on internal movement from the unique associations with the first social distancing mea

28 ansport and slow annihilation highlights the unique attributes of two-dimensional perovskites as an e

29 lical structures presented in this study are unique because they exhibit three distinct helical state

30 stantially overlap, whereas CHU-128 adopts a unique binding mode with a more open receptor conformati

31 rogeneity in the particles and a total of 13 unique binding sites for the LHCIs around the PSI core.

32 biopolymers as building blocks for realizing unique bioenabled photonic structures.

33 Tooth eruption is a unique biological process by which highly mineralized ti

34 ea that will allow for the identification of unique biomarkers for early AD.

35 chaperones, radical chemistry, and novel and unique biosynthetic intermediates.

36 Here, we use a unique blend of crosslinking and immunoprecipitation (CL

37 ypical flavoring profile, characterized by a unique bouquet of volatile compounds, made by nonanoic a

38 an eyes, both healthy and diseased, with the unique capabilities of our adaptive optics-optical coher

39 n, is described here, with exosomes carrying unique cargos, including the GTPase Rab11, generated in

40 This study represents a unique case of stereoselective activity of cis/trans iso

41 ; it also exploited both CCL17-dependent and unique CCL17-driven inflammatory pain and arthritis mode

42 ting are a Gram-negative cell envelope and a unique cell surface antigen; therefore, this approach sh

43 ing this catalog, we characterize shared and unique cellular genes, proteins, and pathways targeted b

44 ion of pyridine in pyridinophanes presents a unique challenge for introducing electrophilic chemical

45 blishes a foundation for understanding their unique channel properties.

46 of AuNPs with silica NPs as a material with unique characteristic comprising large surface area, nar

47 ransition metals and lanthanide ions display unique characteristics (i.e., magnetism, radioactivity,

48 xist; however, accurate understanding of the unique characteristics is crucial and lifesaving treatme

49 Here, we discuss the unique characteristics of blood vessels, the heart, and

50 es have provided exciting insights about the unique characteristics of skin-resident innate lymphoid

51 The study identified unique characteristics of TF viruses thus prompting furt

52 anoparticles with the ability to exploit the unique characteristics of the tumor microenvironment for

53 rn Indian Ocean), to determine any potential unique characters.

54 e of an additional (133)Cs NMR signal with a unique chemical shift that is attributed to Cs atoms ter

55 ine alkaloids and provides insights into the unique chemistry that plants use to generate complex, bi

56 age-specific chromatin reconfiguration and a unique chromatin state for primed pluripotency.

57 y provide new mechanistic insight into how a unique collagen fragment may regulate ovarian cancer, bu

58 he methionine residue at this position has a unique combination of length, flexibility, and chemistry

59 n of ripening in European pear, as well as a unique comparative analysis of the two cultivars with ve

60 presenting 1.9% of all injections, with 1031 unique complications in 685 patients (12.9%).

61 emical technologies, although there are also unique complications that arise from the specifics of th

62 ies are widely acknowledged to depend on the unique composition of lipids within the membrane, yet th

63 At the pointed end, unique contacts between the penultimate and terminal sub

64 bled peptide micelles and fibers demonstrate unique control over the photophysical properties of the

65 te-specific conjugation of two proteins with unique cysteine residues yielding a nonhydrolyzable phos

66 n sea surface temperature (GMSST) by using a unique dataset consisting of 30-member large initial-con

67 soform, VGLUT3, exhibits an overlapping, but unique, distribution with mGluR5, and the dynamic cross

68 comprise a coiled-coil heterodimer pair with unique DNA handles in order to link DNA origami nanostru

69 ions of the intrinsically disordered SH4 and Unique domains of the Src family kinase Hck.

70 most molecularly distinct subtype - possess unique efferent projections and electrophysiological pro

71 t surface ligand engineering can exploit the unique electrochemical properties of individual NPs and

72 Unique electromagnetic response of Weyl semimetals such

73 Here, a unique electrospraying-netting technique is used to crea

74 r of molecular features distinguishing these unique endogenous substrates.

75 However, the unique environment of microdroplets allows different che

76 t 14, 2020 and identified 25 studies with 31 unique estimates of RSV-associated hospitalization rates

77 the full Arabidopsis proteome, indicating a unique evolution of plastid targeting.

78 ared GQDs are highly hydrophilic and exhibit unique excitation independent photoluminescence emission

79 The authors discovered human-unique expansion and maintenance of cerebellar germinal

80 LytR-CpsA-Psr (LCP) enzyme family, offers a unique extracellular target for the development of new a

81 st effects can arise in the absence of human-unique factors and may emerge, in part, because persisti

82 Undocumented Latinx immigrants experience unique factors prior to migration, during migration, and

83 The unique family of DPC-specific proteases Wss1/SPRTN targe

84 The unique feature of GlyMDB is to link microarray data to P

85 An important unique feature of RETrace was the introduction of linear

86 A unique feature of the vertebrate Hh pathway is that sign

87 A unique feature of this study is the use of chemically mo

88 binding a Lewis acid (LA(II)); we used this unique feature to further modulate the electrostatic env

89 Collectively, these data uncover shared and unique features between neural resident macrophages and

90 ted microenvironment is made possible by two unique features of CNS vasculature absent in the periphe

91 ne, and transcriptomic level to identify the unique features of each model.

92 d proteins have been traditionally viewed as unique features of neoplasia, and have been used as biom

93 The new electrochemical microreactor has unique features that allow i) voltage-controlled acceler

94 arifying both the conserved features and the unique features.

95 t evidence for the binding mechanism of this unique fold.

96 lliative care team for more complex cases-is unique from palliative care in adults given its focus on

97 er preclinical mutation carriers demonstrate unique FTD-related symptoms relative to familial mutatio

98 It has recently been recognized for its unique function in the stabilization of mRNA, which is a

99 ve CCL5 expression by CD8(+)T(M) serves as a unique functional imprint of prior antigenic experience;

100 es, we report a diverse click-library of 173 unique functional molecules in minimal synthetic steps.

101 scuss how its structural elements define its unique functional properties.

102 cing, which demonstrate clonal expansion and unique functional states of B cells in responders.

103 bers and carbon fibers as well as to provide unique functionalities.

104 We discovered unique genes expressed by pigment cells and test their e

105 nd isolated from human tonsils but displayed unique genetic features in comparison with those of cont

106 Its unique genomic landscape shaped by oncogenic drivers pro

107 When investigating unique geological samples, such as cometary, asteroidal,

108 Together, the unique geometric features of these undercut MNAs and the

109 In the current study, we identify a unique granulocyte subset, with characteristics of an im

110 emphasis on social behavior, discuss whether unique GRN organization and cis-regulatory architecture

111 These studies captured unique heteroterminal cross talks between the fuzzy inte

112 (2) formation is catalyzed by a biologically unique hexanuclear iron cofactor denoted the H-cluster.

113 he basis of machine learning, CEFCIG reveals unique histone codes for transcriptional regulation of r

114 y occur during periodontal disease result in unique histone methylation signatures in affected cell p

115 Benefiting from the unique host-guest interaction (e.g., Lewis acid-base int

116 The authors injected a unique human isolate of P. vivax that reached high gamet

117 istration, we report on the development of a unique hydrogen peroxide (H(2) O(2) )-sensing motif and

118 s respect, innate and innate-like cells with unique immune properties, such as natural killer (NK) ce

119 The uterus constitutes a unique immunological environment with specific features

120 uss cannabis use as a factor that may have a unique impact during adolescent neurodevelopment, and su

121 ans to cooperate in large-scale societies is unique in animal life, it remains open how such a degree

122 MtClpP1P2 is unique in that it contains a pair of distinct ClpP1 and

123 mutations, the T507K substitution in SHP2 is unique in that it exhibits oncogenic Ras-like transformi

124 leading to a high-quality dataset of 459,777 unique individuals.

125 Quantitative XL-MS (qXL-MS) provides unique information on protein conformational and interac

126 Together, these results demonstrate unique initial cellular triggers as well as converging e

127 central retina, high fidelity IRD provides a unique insight into outer retinal complex function.

128 otype networks from data, but also provide a unique insight into the elusive functional and structura

129 RPV3 in a lipid membrane environment provide unique insights into channel activation and inactivation

130 pecies comparative genomic analysis provides unique insights into glioma etiology and the chronology

131 grate out from a complex tissue and provides unique insights into the roles of Piezo in invasive cell

132 This unique instrument allows for a myriad of novel studies i

133 Collectively, these data show a unique interaction of between pathogenic C difficile and

134 ences from the known channelrhodopsins and a unique ion-conducting pathway.

135 Remarkable and unique is the double probe given by (1)H and (11)B NMR t

136 Thus, viral rhodopsins 1 represent a unique, large group of light-gated channels (viral chann

137 Seventy-one unique life cycle assessment (LCA) studies that quantify

138 Due to their long and unique life cycles, these arthropods likely evolved robu

139 Additionally, we unravel a unique ligand rearrangement for these classes of anionic

140 d repeats in the polymer main chain shedding unique light on the relative contributions of configurat

141 rmations were identified, two of which adopt unique, likely off-pathway, intermediates in the canonic

142 used during this cellular repair, each has a unique localization pattern and knockdown phenotype, dem

143 Mouse embryonic stem cells (mESCs) display unique mechanical properties, including low cellular sti

144 vivo in a spinal cord injury model through a unique mechanism of anti-inflammation-based fibrotic sca

145 Resulting patchwork may give rise to unique metabolic capabilities; on the other hand, it can

146 catalyzed by complex enzyme machineries with unique metal-containing cofactors.

147 Our study reports a unique method of resolution enhancement purely relying o

148 KRAS knockdown resulted in unique methylation changes with limited overlap between

149 Our findings define unique microbiome differences after chronic versus acute

150 utilization of regular surface cavities with unique microenvironment on graphitic carbon nitride as "

151 and Cretaceous Coelosmilia skeletons share a unique microstructure indicating a close phylogenetic re

152 e structure and activity of Lpg2603 reveal a unique mode of regulation of a protein kinase, provide t

153 f data in the electronic health record poses unique modeling challenges.

154 s while reusing only 22 distinct steps in 10 unique modules, with the code able to access 17 differen

155 The unique molecular detail, accuracy, sensitivity, and dyna

156 Unique molecular identifiers (UMIs) remove duplicates in

157 The unique nanoscale X-ray computed tomography verifies the

158 s and, if so, whether it regulates common or unique networks of genes.

159 produced over 100 CVB3 clones harboring nine unique nucleotide "barcodes." Using this collection of b

160 We hypothesized that unique obesity-inflammation HFpEF phenotypes exist and a

161 r covalently crosslinked networks, possess a unique, often dormant ability to activate one or more fo

162 DNA-nanoparticle conjugates, where multiple unique oligonucleotides displayed on a nanoparticle form

163 ng both Bronsted and Lewis acid sites offers unique opportunities to tailor shape selectivity and enh

164 rials exhibiting framework flexibility offer unique opportunities to tune these properties since the

165 DNA methyltransferases (MTases) represent a unique opportunity for bacterial epigenomic studies.

166 ance mass spectrometry (FTICR MS) provides a unique opportunity for molecular analysis of natural com

167 Oscillatory behavior provides a unique opportunity for quantitating the robustness of me

168 t 500 km from the Chicxulub crater - offer a unique opportunity to determine an extinction process du

169 xed with solvents, ionic liquids provide the unique opportunity to investigate ion dissociation from

170 Our calculations provide a unique opportunity to observe the molecular orbitals tha

171 RAs(3) where R = Ca, Sr, thus, offers a unique opportunity to realize an archetype nodal-loop se

172 on (CHMI) to assess vaccine efficacy offer a unique opportunity to study the immune response during P

173 anoparticle-based materials and devices with unique optical properties at the macroscale.

174 ial role in bacterial sensing owing to their unique optical, magnetic, and electrical properties.

175 aces with its host erythrocyte (RBC) using a unique organelle, the parasitophorous vacuole (PV).

176 ntified 129 outcomes which were mapped to 43 unique outcome terms for the Delphi survey.

177 A unique output of this approach, the "dynamic correlation

178 le in governing the molecular geometries and unique packing of Y6 and CH1007 to ensure their superior

179 or born between 1968 and 2013 (n = 4,255,196 unique pairs and 8,343,951 offspring).

180 r dynamics simulations, we go on to identify unique paralogs in M. stadtmanae and Methanobrevibacter

181 Patients harbored up to seventeen unique parasite lineages.

182 Depletion of CD4(+) T cells showed unique pathological bulbar vacuolation in the brain pare

183 RAI assessments were completed on 36,261 unique patients presenting to surgical clinics across fi

184 c 29, 2018, we enrolled 478 patients and 462 unique patients were included: 225 children (aged <18 ye

185 Using a cohort of 4967 unique patients with Enterobacterales bloodstream infect

186 The analysis showed a unique pattern, not detected in other parts of Poland; m

187 Our targeting approach is based on pHLIP, a unique peptide that selectively targets tumors in vivo b

188 in cells (pSILAC), phosphoproteomics, and a unique peptide-level matching strategy, our DeltaSILAC p

189 ptional control that manifests only during a unique period of the lifespan where dynamic hormonal cha

190 ar basis of cell-cell recognition, including unique phenomena associated with neuronal interactions.

191 Each protein introduces a unique phenotype to chromatin organization, and these st

192 KMT2D NCC loss-of-function does exhibit unique phenotypes distinct from UTX mutation, including

193 We also identify a unique phosphatidylinositol (4,5)-bisphosphate (PIP(2))

194 ic DNA scaffold and consequently, to use the unique photophysical properties of An-BA to improve glyc

195 Fundamentally, the unique photoresponse induced by oxidation-related defect

196 The unique physical and chemical properties of fullerenes ha

197 This unique placement in the periodic table makes catenated n

198 etween plants and metazoans and highlighting unique plant-specific features.

199 ogonal nature of perfluorocarbons provides a unique platform for introducing dynamic nano- and microd

200 to adopt a specific conformation, represent unique platforms for efforts to harness principles of en

201 nstrate that all four PARP inhibitors have a unique polypharmacological profile across the kinome.

202 f lymphatic endothelial cells.Conclusions: A unique population of LAM(CORE) cells was identified in l

203 Using a unique, population-level dataset, we find that rates of

204 plifying asymmetric autocatalysis-occupies a unique position in organic chemistry and stands as an em

205 Therefore, each output module exhibits a unique position within the claustrum and overlaps substa

206 Microstimulation+imaging opened a unique possibility for investigating the connectivity of

207 In this context, electrosyntheses create the unique possibility to replace stoichiometric amounts of

208 Other studies have noted unique, possibly compensatory patterns of neural activit

209 October 3, 2018 release of GO suggested 1938 unique potentially missing is-a relations.

210 an at baseline, suggesting that MDD-PRS adds unique predictive power in depression prediction.

211 rformance per se, being heritable and having unique predictive value for long-term memory function, h

212 ories (REC) and institution for 40 published unique procedure types.

213 This unique process is compatible with both internal and term

214 on relating sequences of antibodies to their unique properties as inhibitors.

215 re three-dimensional aluminosilicates having unique properties from the size and connectivity of thei

216 This regulation results from unique properties of proteins under LLPS conditions, whe

217 ed to numerous material systems to introduce unique properties, from textiles to biomedical applicati

218 These needle-injectable cryogels have unique properties, including large and interconnected po

219 a synthetic opioid agonist with notoriously unique properties, such as lower abuse liability and ind

220 r van der Waals chalcogenophosphates exhibit unique properties, such as negative electrostriction and

221 pression.Conclusions: Here, we demonstrate a unique protective role for pulmonary endothelial HIF-2al

222 es, 516 million genes and almost 100 million unique protein sequences are currently stored in the dat

223 The authors sought to identify unique proteomic signatures for patients with HF with re

224 nd their respective role in the structurally unique pseudo-heterodimer PfCCT protein in a heterologou

225 led insights and unexpected findings for the unique reaction mechanism.

226 utane-1,3-diyls are fascinating due to their unique reactivity and electronic properties.

227 l modalities provide gammadelta T cells with unique recognition capabilities relative to alphabeta T

228 GPRC6A's unique regulation of beta-cell, skeletal muscle and hepa

229 eal that RNase L promotes the formation of a unique RNP complex that may have roles during the RNase

230 ictor of disability-is poor, questioning the unique role of axonal loss.

231 e distinct from that of RuvC, highlighting a unique role of this loop region in Fpr-HJ interaction.

232 ported spin Hall angle values and reveal the unique role of TSS in generating SOT.

233 two sets of information simultaneously in a unique sample collected from a single cultivation, there

234 he yield and available information from each unique sample.

235 Here, we present a unique sedimentary record of the backwash from two histo

236 ritical functional importance and revealed a unique sequence signature that is potentially responsibl

237 Here, we use millions of unique sequences from a DNA-based digital data archival

238 This photoactivation involves a unique series of structural changes which terminate with

239 rative neoplasm (MPN) are characterized by a unique set of cytogenetic and molecular features distinc

240 We conclude that TWIK-1 displays unique SF gating properties among the family of K2P chan

241 Unique signatures of in vivo competition in gnotobiotic

242 In summary, we have identified a unique single-disulfide conopeptide with a noncompetitiv

243 h other C-H azidation methods highlights its unique site selectivity, and conversions of the benzyl a

244 inations by multiple parasitologists using 4 unique slide sets.

245 Understanding our unique social psychology requires accounting not only fo

246 unds from hydrothermal vent fluids through a unique solid phase microextraction (SPME) sampler.

247 tArc reveals 35 million deletions (~ 470,000 unique spans) in skeletal muscle from 22 individuals wit

248 ng and computational analysis, we discovered unique spatial designs comprising mixed interbacterial s

249 Each motif captured a unique spatiotemporal pattern of neural activity across

250 We define the structures of two unique species-specific components (Cag3 and CagM) and s

251 ypic and gene expression profiles revealed a unique spectrum of memory-type differentiation of T-PLL

252 es)(NP(pip)(3))(4)], 2-U(PN)NMes, exhibits a unique square pyramidal geometry in contrast to the expe

253 Unique stimuli stand out.

254 vious hepatobiliary metastasis and stemness, unique stromal properties, and dysfunctional intratumora

255 ll-defined Ru(II)-NHC-diamine complexes show unique structure and coordination chemistry including an

256 re identified, and 68 papers reporting on 56 unique studies were eligible for inclusion.

257 Our unique study uses a novel combination of human associati

258 % [corresponding to 1:313]) among 10,921,310 unique subjects in the general population (33,036 patien

259 A total of 157 unique subjects participated in home and clinical visits

260 % (95% CI: 2.2% to 4.3% [1:31]) among 84,479 unique subjects with IHD (2,103 patients with FH) on the

261 % (95% CI: 4.9% to 8.7% [1:15]) among 31,316 unique subjects with premature IHD (1,471 patients with

262 (95% CI: 4.6% to 10.8% [1:14]) among 17,728 unique subjects with severe hypercholesterolemia (920 pa

263 Humeri of stem tetrapods share a unique suite of functional adaptations, but do not confo

264 ch year and is distinguished by abundant and unique surface glycan structures that are rich in xylose

265 This unique system represents a collaboration between the pat

266 We used GLIPH2 to analyze 19,044 unique TCRbeta sequences from 58 individuals latently in

267 ng this adaptation tumor cells might present unique, temporally restricted collateral sensitivities,

268 Other than its unique tetranuclear active site Cu(Z), the binuclear ele

269 With the unique three-dimensional structure of laser-induced grap

270 onstruction of a vaccine platform based on a unique three-plasmid system to efficiently generate reco

271 The avascular nature of cartilage makes it a unique tissue(1-4), but whether and how the absence of n

272 d, to identify DNAm smoking effects that are unique (tissue-specific) vs. shared between tissues (tis

273 ber of species or the portion of a phylogeny unique to a site - showed stronger, more consistent resp

274 Of the long ncRNAs unique to bacteria, the OLE (ornate, large, extremophili

275 with immune systems that diverge from those unique to bats.

276 ockout mouse models and molecular inhibitors unique to necroptotic proteins, this cell death has been

277 These changes are unique to NFLP and enable additional hydrogen bonds with

278 terminal Repression Domains (RDs), which are unique to Pumilio orthologs.

279 ion; these key fundamental pai functions are unique to sp(2) carbon-conjugated frameworks and cannot

280 To address the challenges unique to this age group, novel strategies to provide th

281 re aspects of AKI risk, course, and outcomes unique to this infection.

282 nt of known clathrate types while others are unique to this structure type.

283 es among a Proteobacteria-dominant community unique to toddlers with stunted growth from Bangladesh,

284 rates great promise for its application as a unique tool for manipulating input-defined cell populati

285 matergic neurotransmission, thus making it a unique tool to investigate the brain and its complex neu

286 This work provides unique tools to modulate aGPCR-ligand binding and establ

287 hich is rapidly transforming into a suite of unique tools with the potential for future therapeutics.

288 Attributed to the unique topological complexity and elegant beauty, Borrom

289 The unique topology of MUL1 enables it to "sense" mitochondr

290 role in myogenesis, but the asynchronous and unique trajectory of differentiation of each myoblast al

291 eq analyses revealed that ROCK2 controlled a unique transcriptional program in GC B cells that promot

292 ER1 deleted uteri or Ishikawa cells revealed unique transcriptomic profiles and global miRNA downregu

293 This provides a unique translational opportunity to investigate therapeu

294 n apical complex harboring a conoid, made of unique tubulin polymer fibers.

295 Here, utilizing K(V)7.1's unique two open states, we report a two-stage E-M coupli

296 inergic neurons (DANs) reinforce memories of unique valence and provide state-dependent motivational

297 The electrolyte exhibits unique vibrational signatures from stimulated Raman spec

298 ll studied for their aggressive behavior and unique visual system as well as their commercial importa

299 can alter the fate of substrate proteins in unique ways.

300 d passively acquired antibodies, providing a unique window into immune correlates of HIV risk.