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1 ion of aversive sounds that are perceived as unpleasant.
2 d affection that make one's life pleasant or unpleasant.
3 teers, although they correctly rated them as unpleasant.
4 d to determine whether they were pleasant or unpleasant.
5 , difficult and inaccurate, and occasionally unpleasant.
6 ods (e.g., blood draws) are inconvenient and unpleasant.
7 or and color were regarded as unfamiliar and unpleasant.
8 c valence: perceiving stimuli as pleasant or unpleasant.
9 cluding adenosine, which patients often find unpleasant.
10 he entire valence dimension from pleasant to unpleasant.
11 etermine response to pleasant (vanillin) and unpleasant (4-methylvaleric acid) odors, compared betwee
15 nments during or surrounding the experience, unpleasant acute experiences (classic psychedelics), pri
16 d broad evaluative judgments (e.g., pleasant/unpleasant), aesthetic experiences involve emotions of d
18 teviol glycosides Reb D and Reb M, devoid of unpleasant aftertaste, are naturally produced only in tr
19 to affectively normed pictures: pleasant vs. unpleasant (an internally cued condition, ICC) and indoo
20 and are termed "consonant," but others sound unpleasant and are termed "dissonant." The distinction b
21 investigate how inflammation is perceived as unpleasant and causes negative affect, we used a behavio
25 m concentration, and because this therapy is unpleasant and occasionally is associated with serious c
26 obal population, chronic visceral pain is an unpleasant and often excruciating reminder of the existe
28 quired during the neutral condition with the unpleasant and pleasant image sets and the unpleasant an
30 ty induction, initially neutral odors become unpleasant and take longer to detect, accompanied by aug
35 ce for drug-related vs affectively pleasant, unpleasant, and neutral images), and underwent positron
36 evised a series of tasks involving pleasant, unpleasant, and neutral olfactory stimuli, designed to s
38 method avoids the use of less accessible and unpleasant arenethiols as starting materials, instead ut
39 enhance fruity and floral aromas and reduce unpleasant aromas, showing as good modulators of white w
43 nown as cucurbitacins are known to impart an unpleasant bitter taste to edible fruits and even lead t
44 Melanopsin stimulation was described as an unpleasant, blurry, minimal brightening that quickly fad
45 A well-documented link between avoidance of unpleasant body sensations and BN symptoms suggests that
47 ponses to stimuli from broad "pleasant" and "unpleasant" categories and ignore the variation of motiv
48 nthol, icilin) and are implicated in sensing unpleasant cold stimuli as well as in mammalian thermore
49 ing on context, TRPM8 contributes to sensing unpleasant cold stimuli or mediating the effects of cold
51 temic inflammation, individuals smelled more unpleasant compared to a placebo group (saline injection
52 perculuar region responded preferentially to unpleasant compared to pleasant tastes equated for inten
53 valence, enhanced by pleasant and reduced by unpleasant, compared to neutral stimuli, only when task
57 l, and medial frontal cortex relative to the unpleasant condition and in the cingulate, precuneus, an
58 enoted by concrete nouns (i) had pleasant or unpleasant connotations, (ii) were typically smaller or
62 r, ProGel showed marked benefits in reducing unpleasant discharge, reducing product-related toxicity,
68 de tradeoff between money for themselves and unpleasant electric shocks to another person, and a mora
69 significant visual scenes, both pleasant and unpleasant, elicit a larger late positive wave in the ev
72 terized by greater intensity of reactions to unpleasant emotional cues and a slower-than-normal retur
74 herapies for BPD such as gradual exposure to unpleasant emotional stimuli or amygdala neurofeedback m
75 a difference (P = .050) in negative affect (unpleasant emotions such as distress), with patients und
76 ve treatment and higher efficacy in stopping unpleasant emotions were associated with both higher phy
77 ion to cause a diarrheal illness that, while unpleasant enough in healthy people, is devastating in i
79 onditioned stimulus associated with the most unpleasant event in each context: the absence of the rew
82 ould show blunted reactivity during aversive/unpleasant events, as indexed by diminished emotional mo
87 of the population reporting NSSH to relieve unpleasant feelings of anger, tension, anxiety, or depre
90 food preservative but it presents strong and unpleasant flavor that alters the sensory characteristic
91 lavor compounds along with the occurrence of unpleasant flavors was detected in chickpea flours upon
92 beans (Phaseolus vulgaris L.) is hindered by unpleasant flavors, low macronutrients digestibility, an
95 is article is twofold: first, we bridge this unpleasant gap by presenting an [Formula: see text]-time
99 , the RTL group produced significantly fewer unpleasant/high intensity memories than the other groups
101 t stopping episodic retrieval to suppress an unpleasant image triggers parallel inhibition of mnemoni
102 d p = 0.01), and amygdala recovery following unpleasant images (R(2) = 0.40, FWE-corrected p < 0.05),
103 tly and selectively to neutral, pleasant, or unpleasant images and lesioning these neurons by setting
104 elated stress, enhanced neural reactivity to unpleasant images predicted greater externalizing sympto
105 across all picture categories; pleasant and unpleasant images prompted larger Late Positive Potentia
106 ctive to noxious heat and passive viewing of unpleasant images suggest that the cerebellum may contai
107 When patients consciously evaluated the unpleasant images, they did not activate the phylogeneti
109 tened neural reactivity and attention toward unpleasant information, as measured by the LPP, predispo
111 esponses, and light tactile touch may induce unpleasant itch sensations (mechanical itch or alloknesi
113 ted retrieval stopping reduces intrusions of unpleasant memories and diminishes their affective tone,
114 m, here we successfully disrupt retention of unpleasant memories by subliminally reactivating them wi
115 HC+ patients produced a lower proportion of unpleasant memories compared with the other participants
116 This study suggests that even relatively unpleasant memories for real events during critical illn
117 ntentional suppression may be used to weaken unpleasant memories, such sleep-based strategies may hel
118 ps generated similar numbers of pleasant and unpleasant memories, whereas the right temporal lobectom
120 primary outcome was psychological distress (unpleasant mental or emotional experiences including anx
121 g in the ventral striatum while listening to unpleasant music, and involvement of the thalamic pulvin
122 ytic and antiamnestic activities without the unpleasant myorelaxant side effects of the classical 1,4
123 iew a mixed series of pleasant, neutral, and unpleasant natural scenes, balanced for basic perceptual
124 representations of distinct (but comparably unpleasant) negative states, pain, and disgust, as conve
125 recordings while passively viewing pleasant, unpleasant, neutral and cocaine images, during which ear
128 ing a task involving an intermixed series of unpleasant, neutral, and pleasant pictures each presente
131 ciated increase in anaerobes may account for unpleasant odor and a possible heightened risk of tetanu
133 oducts, known to be caused by at least three unpleasant odorants, with very low odour thresholds.
134 petitively paired with pleasant, neutral, or unpleasant odors [the unconditioned stimuli (UCS)] in a
135 Intensity changes were most pronounced for unpleasant odors and for tastes perceived strongly as ei
137 ts suggest that treatment by rotovap removes unpleasant odors from noni juice and mixture with pineap
138 with schizophrenia subjectively experienced unpleasant odors in a manner similar to healthy voluntee
139 y bands and suggest that rapid processing of unpleasant odors in the OB might underlie rapid approach
140 stments in sniffing patterns to pleasant and unpleasant odors may provide a window into early diagnos
141 ifolia, has multiple health benefits but the unpleasant odors of raw juice limits consumer adoption.
142 tex, neural responses evoked by pleasant and unpleasant odors were segregated within medial and later
143 hy participants were exposed to pleasant and unpleasant odors while rCBF was measured using [(15)O] w
144 ahippocampal gyrus) during the experience of unpleasant odors, recruiting a compensatory set of front
145 odors involved larger sniffs than imagery of unpleasant odors, suggesting that the act of sniffing ha
149 orthonasally-presented pleasant (orange) and unpleasant odours (trimethyloxazole and hexenol) and cle
150 ioural variant frontotemporal dementia rated unpleasant odours as less aversive than did controls and
151 ly differentiate the valence of pleasant and unpleasant odours correlated with atrophy in right ventr
153 g powders was observed during storage, while unpleasant odours were perceived when the egg powders we
154 different categories (pleasant, neutral, and unpleasant) of affective images from the International A
156 isolates, lipases and lipoxygenases catalyse unpleasant off-taste reactions, which hamper the applica
157 ts of valenced contextual cues (pleasant vs. unpleasant) on emotional attribution (the rating of subt
159 ithdrawal and the experience of an intensely unpleasant or painful sensation, nociceptors are essenti
161 ask where their responsibility in causing an unpleasant outcome to a social partner was manipulated.
165 articipants (and 19 confederates) to equally unpleasant painful and disgusting stimulations, as well
166 n EoE patients, characterized by an intense, unpleasant/painful sensation occurring rapidly and repro
167 ed immediate response of the esophagus is an unpleasant/painful sensation, unrelated to dysphagia, oc
168 However, because lung disease makes activity unpleasant, patients with chronic obstructive pulmonary
169 endence, which is characterized by extremely unpleasant physical and emotional feelings after drug us
171 d functional overlap with both heat pain and unpleasant picture viewing were significantly inversely
173 sive stimuli in the form of noxious heat and unpleasant pictures (unpleasant vs neutral) activated ov
174 s with BPD showed greater overall AMS during unpleasant pictures and prolonged habituation of startle
175 , relative to neutral pictures, pleasant and unpleasant pictures elicited enhanced LPP, as well as he
177 es showing deficient amygdala habituation to unpleasant pictures in BPD; and 3) have significant impl
179 at abnormal processing of and habituation to unpleasant pictures is observed in BPD but not schizotyp
180 cortex, amygdala, and precuneus, whereas for unpleasant pictures significant LPP-BOLD correlation was
181 patients with BPD, prolonged habituation to unpleasant pictures was associated with greater symptom
183 ERP) were measured when pleasant, neutral or unpleasant pictures were presented in the context of sim
184 gh and low emotionally arousing pleasant and unpleasant pictures, cigarette-related, and neutral pict
188 e major factors, along with being exposed to unpleasant placement experiences, the attitudes of place
189 this might to some extent converge with the unpleasant-pleasant continuum, subjective liking might d
190 nto a pattern continuum between pleasant and unpleasant poles, offers a robust mechanism by which con
191 nt), we characterized neural activity during unpleasant portions of three separate paradigms (negativ
192 t music may be perceived as a diversion from unpleasant proprioceptive sensations that go along with
193 sant sweet taste (1 M glucose), a moderately unpleasant salt taste (0.2 M saline), or a neutral taste
195 testing in children is often hampered due to unpleasant sample collection, limited RT-qPCR capacities
197 sociated with IC, which can be defined as an unpleasant sensation including pain and discomfort relat
203 of itch (formally known as pruritus) as an "unpleasant sensation that elicits the desire or reflex t
208 e cornea may be useful to selectively relief unpleasant sensations and pain associated with mechanica
209 Excessive coffee consumption can lead to unpleasant sensations such as tachycardia and heart palp
210 similar to movements triggered internally by unpleasant sensations, as has been shown for pain or itc
213 multisensory fMRI task designed to mimic the unpleasant sensory experiences that adolescents and adul
214 in the body occurred in three patients, with unpleasant sensory symptoms in denervated posterior cerv
215 table and unpredictable aversive stimuli, an unpleasant shock or a less aversive airblast to the lary
216 does not replicate circadian rhythms and has unpleasant side effects especially due to the failure to
221 such as, the high cost of transportation, an unpleasant smell, the risk of pathogens, and pharmaceuti
227 pressed the encoding of emotionally arousing unpleasant stimuli and reduced amygdala activation in he
228 ore negative (Hedges g = 0.55; P <.001), and unpleasant stimuli as both more positive (unipolar posit
230 f alertness and that the reduced response to unpleasant stimuli is caused by a selective inhibitory m
233 Observing and assigning emotional value to unpleasant stimuli produced activations in subcortical l
234 at the LPP was larger following pleasant and unpleasant stimuli than it was following neutral stimuli
235 ircuit mechanisms by which these cells relay unpleasant stimuli to DA neurons and regulate behavioral
236 ons in a single brainstem nucleus that relay unpleasant stimuli to the mesolimbic DA system through d
237 ased P300 and LPP amplitudes to pleasant and unpleasant stimuli, especially in centroparietal regions
243 euroticism-PGS was associated with living in unpleasant surroundings (OR = 1.09; p = 0.007) and major
246 from alcohol is associated with a number of unpleasant symptoms that play an important role in preve
247 through the identification and targeting of unpleasant symptoms via a tailored palliative care appro
251 bo (by 1.5 points [95% CI, 0-4.0]; P = .03), unpleasant taste (by 1.5 points [95% CI, 0-3.0]; P = .00
252 0.6 (0.74), while the high-volume group gave unpleasant taste a score of 2.2 (0.97) and the medium-vo
253 haracteristic smell of moist soil as well as unpleasant taste and odor episodes associated with publi
257 as associated with more stinging or burning, unpleasant taste, and greater drowsiness than the placeb
259 st common adverse events with cotherapy were unpleasant taste, headache, dry mouth, and somnolence.
260 onded preferentially to pleasant compared to unpleasant taste, irrespective of intensity, and the lef
263 ttracting consumers, yet many fruits contain unpleasant-tasting chemicals that deter consumption by v
264 istent rank-order preferences, with the most unpleasant textures (as rated by both groups) exhibiting
266 olate, subjects gave ratings of how pleasant/unpleasant the chocolate was and of how much they did or
267 can arise when people encounter reminders to unpleasant thoughts they prefer not to think about.
268 d PCR is sensitive, swabbing is invasive and unpleasant to administer, reducing patient compliance fo
269 indicate the body regions they find soothing/unpleasant to be touched by a loved one versus an acquai
271 imensional valence code is that pleasant and unpleasant valence cannot coexist in the amygdale becaus
277 stibular dysfunction or motion sickness, the unpleasant visceral manifestations (e.g. epigastric disc
279 onses to non-stressful neutral, pleasant and unpleasant visual stimulation (VES) via emotionally lade
282 ibute to consumer preferences while reducing unpleasant volatiles, by selection of the relevant allel
283 orm of noxious heat and unpleasant pictures (unpleasant vs neutral) activated overlapping areas in th
286 donic view that drug pleasure and subsequent unpleasant withdrawal symptoms are the chief causes of a