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1 roscopy and the probability that disease was unresectable.
2 Of these, 5 were unresectable.
3 identifying lesions that were endoscopically unresectable.
4 p invasion and 91 (4.3%) were endoscopically unresectable.
5 surgically and are considered endoscopically unresectable.
7 rgically explored, 530 (49%) were considered unresectable (286 locally unresectable, 244 with distant
10 rolled patients aged 20 years and older with unresectable advanced or recurrent oesophageal squamous
15 nts and Methods Patients < 18 years old with unresectable and/or progressive therapy-naive PLGG were
16 ncer stage III LA/BR PDAC who were initially unresectable, as determined by staging computed tomograp
19 is best suitable for locally invasive tumors unresectable because of location and vascular involvemen
22 iopsy-confirmed HCC or ICC, determined to be unresectable by multidisciplinary review, with a Child-T
26 emerged as a valuable therapeutic option in unresectable, chemotherapy-refractory hepatic metastases
29 ents with previously untreated metastatic or unresectable clear-cell renal-cell carcinoma received or
31 or never should be resected in patients with unresectable colorectal cancer metastases must be questi
33 Evaluate conversion rate of patients with unresectable colorectal-liver metastasis to complete res
34 0 resection rates in patients with primarily unresectable CRLM as evidenced in a recent randomized co
35 first evidence that patients with primarily unresectable CRLM treated by ALPPS have not only low per
39 l lymph nodes (n = 47), and locally advanced unresectable disease (n = 18), that is, 6-DL and 69-UDL.
40 apeutic laparotomy in 55.9% of patients with unresectable disease and 23.2% of overall GBC patients.
44 o underwent laparotomy, an additional 75 had unresectable disease due to surface liver metastasis (n
46 th using radiation to approximate surgery in unresectable disease is that the radiation dose required
49 randomised, phase 3 trial, had metastatic or unresectable disease, Eastern Cooperative Oncology Group
50 however, for patients with advanced stage or unresectable disease, locoregional and systemic chemothe
58 patients with liver malignancies considered unresectable due to an insufficient FLR who underwent AL
60 otherapy-naive adults (aged >=18 years) with unresectable epithelioid malignant pleural mesothelioma
61 el treatment strategies for deadly recurrent unresectable forms of this soft tumor subtype, but also
63 f regorafenib in patients with metastatic or unresectable GIST progressing after failure of at least
64 with histologically confirmed, metastatic or unresectable GIST, with failure of at least previous ima
67 ying invasive polyps that are endoscopically unresectable (have at least 1 risk factor for metastasis
68 hepatocellular carcinoma (HCC) are <50%, and unresectable HCC carries a dismal prognosis owing to its
72 (96 men, 20 women; mean age, 63 years) with unresectable HCC who underwent at least two chemoemboliz
80 n shown to improve survival in patients with unresectable HCC; it has also been successfully used as
84 [SIRT]) is a valuable therapeutic option for unresectable hepatic metastases arising from primary col
86 For the management of selected children with unresectable hepatoblastoma, an almost opposite strategy
88 survival and tumor response in patients with unresectable hepatocellular carcinoma (HCC) treated with
91 to compare survival of patients treated for unresectable hepatocellular carcinoma (uHCC) with (90)Y
92 han with atezolizumab alone in patients with unresectable hepatocellular carcinoma not previously tre
93 Study of Liver Diseases criteria) confirmed unresectable hepatocellular carcinoma that was not amena
94 standard of care for patients with advanced unresectable hepatocellular carcinoma, but the relation
98 OLT in appropriately selected patients with unresectable ICCA demonstrated promising disease recurre
99 al can be achieved in selected patients with unresectable ICCA using a combination of OLT and neoadju
104 ly with thoracic radiation for patients with unresectable IIIA and IIIB non-small-cell lung cancer (N
105 rolled and analyzed; inclusion criteria were unresectable IIIA/IIIB histologically confirmed NSCLC, K
106 atients with relapsed ALCL and metastatic or unresectable IMT highlight the importance of the ALK pat
107 th cytotoxic drugs is standard treatment for unresectable intermediate-stage hepatocellular carcinoma
108 neoadjuvant) versus patients presenting with unresectable lesions, for which chemotherapy is used to
109 one of the principal tools in management of unresectable liver malignancies, including colorectal li
111 emotherapy can be recommended for downsizing unresectable liver metastases, but not for resectable le
114 LPPS procedure, aiming at removing primarily unresectable liver tumors, has been criticized for safet
116 who undergo yttrium 90 radioembolization for unresectable liver-dominant metastatic colorectal cancer
117 in 20 hospitals in the UK for patients with unresectable, liver-confined hepatocellular carcinoma.
121 igned 495 patients with previously untreated unresectable locally advanced or metastatic BRAF V600 mu
123 g efficacy and moderate survival duration in unresectable locally advanced or metastatic esthesioneur
124 We recruited adults (aged >/=18 years) with unresectable locally advanced or metastatic gastric or g
125 We recruited patients (>/=18 years old) with unresectable locally advanced or metastatic gastric or o
126 ulticohort study that includes patients with unresectable locally advanced or metastatic urothelial c
127 logical evidence of metastatic or surgically unresectable locally advanced sarcoma, had received up t
128 years or older with metastatic or surgically unresectable locally advanced urothelial carcinoma, meas
130 en aged 18 years or older with HER2-positive unresectable, locally advanced or metastatic breast canc
131 lizumab plus nab-paclitaxel in patients with unresectable, locally advanced or metastatic triple-nega
132 d, phase 3 trial in patients with untreated, unresectable, locally advanced or metastatic urothelial
133 8 years or older with histologically proven, unresectable, locally advanced or metastatic, HER2-posit
134 number of previous chemotherapy regimens for unresectable, locally advanced, or metastatic disease (0
135 d for HER2-positive advanced gastric cancer (unresectable, locally advanced, or metastatic gastric ca
136 han drug' for the treatment of patients with unresectable, locally advanced, or metastatic medullary
137 e, HER2-positive advanced breast cancer with unresectable, locally advanced, recurrent or metastatic
139 rial evaluated ramucirumab with docetaxel in unresectable, locally recurrent, or metastatic breast ca
141 ey met the following criteria: metastatic or unresectable lung cancer harbouring a RET rearrangement,
142 herapy with RF ablation after SPACE to treat unresectable lung tumors is technically feasible, safe,
148 In the subpopulation of patients with an unresectable meningioma and refractory to radiotherapy,
150 are promising tools for treating progressive unresectable meningioma, especially in cases of high tra
156 view the landscape of systemic therapies for unresectable metastatic colorectal cancer during the cur
157 overall survival of patients diagnosed with unresectable metastatic colorectal cancer has increased
158 FOLFOXIRI-Bev for the treatment of initially unresectable metastatic colorectal cancer in humans were
160 c NET and 41 with nonpancreatic GEP NET) had unresectable metastatic disease graded as G1 or G2 (G1/G
163 0 years and older with previously untreated, unresectable, metastatic colorectal cancer, who were not
164 18 years or older, had BRAF(V600E)-mutated, unresectable, metastatic, locally advanced, or recurrent
166 In this retrospective study, patients with unresectable MHO were separated into the plastic stent (
171 ficult to select treatment for patients with unresectable NETs because some patients can survive deca
172 improves survival in patients with stage III unresectable non-small-cell lung cancer when given as ma
173 cally or cytologically documented stage III, unresectable non-small-cell lung cancer, for which they
174 onsidered for the treatment of patients with unresectable nonmetastatic disease and for patients with
175 and Methods Chemotherapy-naive patients with unresectable, nonsarcomatoid MPM (Eastern Cooperative On
176 Concurrent chemotherapy and PBT to treat unresectable NSCLC afford promising clinical outcomes an
180 be an effective treatment for patients with unresectable or metastatic DFSP, associated with respons
182 and Drug Administration for the treatment of unresectable or metastatic melanoma in patients with Bra
183 D-1 mAbs for the treatment of BRAF-unmutated unresectable or metastatic melanoma is a landmark for th
184 untreated BRAF Val600Glu or Val600Lys mutant unresectable or metastatic melanoma who were treated wit
186 roximately one third of the patients who had unresectable or metastatic melanoma with a BRAF V600E or
187 ligible patients were 18 years or older, had unresectable or metastatic melanoma, and progressed afte
192 n plus olaratumab treatment in patients with unresectable or metastatic soft-tissue sarcoma at 16 cli
193 ars or older with a diagnosis of an advanced unresectable or metastatic soft-tissue sarcoma, of inter
195 they had pathologically confirmed, advanced (unresectable or metastatic), non-functional, well-differ
196 ult patients (aged >18 years) with advanced (unresectable or metastatic), well differentiated carcino
197 lly or cytologically confirmed advanced (ie, unresectable or metastatic, or both) incurable solid tum
199 rare, with limited therapeutic options when unresectable or metastatic; however, expression of somat
200 nts were eligible if their tumour was either unresectable or of low surgical curability on the basis
201 trial we enrolled patients with metastatic, unresectable, or locally advanced NSCLC from 121 sites i
202 cetaxel for patients with locally recurrent, unresectable, or metastatic HER2-positive breast cancer.
203 We included patients with locally advanced, unresectable, or metastatic high-grade soft-tissue sarco
204 with previously untreated locally advanced, unresectable, or metastatic soft-tissue sarcoma were scr
205 xorubicin in patients with locally advanced, unresectable, or metastatic soft-tissue sarcomas and so
210 nable ablative doses of cytotoxic therapy in unresectable pancreatic cancer by reducing untoward morb
212 data of consecutive patients with initially unresectable pancreatic cancer treated by neoadjuvant tr
213 s the first line treatment for patients with unresectable pancreatic cancer, however, insufficient dr
214 on therapy to GEM in patients with localized unresectable pancreatic cancer, with acceptable toxicity
215 and resection in 280 patients with initially unresectable pancreatic cancer-the largest single-center
221 on therapy in patients with locally advanced unresectable PDA have reported mixed results, with effec
222 expansion, trial for patients with advanced, unresectable PDAC (n = 27), ATRA is re-purposed as a str
223 th borderline resectable or locally advanced unresectable PDAC receiving SOC neoadjuvant chemotherapy
224 cribed in detail for patients with initially unresectable PDAC undergoing resection after neoadjuvant
225 tion after neoadjuvant therapy for initially unresectable PDAC, preoperative CA 19-9 levels, lymph no
228 part of the study included patients with an unresectable PDGFRA D842V-mutant gastrointestinal stroma
230 chemoradiation and liver transplantation for unresectable perihilar cholangiocarcinoma caused the Uni
231 n age, 64.0 years; 10 women and 29 men) with unresectable pleural mesothelioma were treated with repe
233 centres across 19 countries in patients with unresectable pleural or peritoneal malignant mesotheliom
234 a better outcome than patients with multiple unresectable PM (5-year OS, 88%, 92%, and 48%, respectiv
235 ients with histologically confirmed GIST and unresectable primary lesion or metastases undergoing an
236 well tolerated for patients with previously unresectable primary tumors and known metastatic disease
237 an 50% tumor resection at diagnosis, or with unresectable progressive disease after surgery alone.
240 e consecutive adult patients with surgically unresectable single or multifocal measurable HCC and ade
242 ntially offers more efficacious treatment of unresectable solid tumors without significant adverse si
244 microwave ablation (MWA) in the treatment of unresectable solitary hepatocellular carcinoma (HCC) up
246 nters with 42 patients who had inoperable or unresectable stage II to stage III NSCLC enrolled from N
247 andomized radiation dose-escalation trial in unresectable stage III non-small-cell lung cancer (NSCLC
248 was to compare the survival of patients with unresectable stage III non-small-cell lung cancer (NSCLC
249 ble-blind trial that recruited patients with unresectable stage III non-small-cell lung cancer who ha
250 e enrolled patients (aged >/= 18 years) with unresectable stage III non-small-cell lung cancer, a Zub
253 a In Solid Tumors version 1.1 (RECIST v1.1), unresectable stage III or IV melanoma (excluding ocular
254 Eligible patients (aged >/=18 years) with unresectable stage III or IV melanoma (treatment-naive o
255 18 years or older with previously untreated, unresectable stage III or IV melanoma and an Eastern Coo
256 rticipants were aged 18 years or older, with unresectable stage III or IV melanoma previously untreat
257 rvival and overall survival in patients with unresectable stage III or IV melanoma receiving epacados
258 atio, 945 previously untreated patients with unresectable stage III or IV melanoma to nivolumab alone
259 18 years or older with previously untreated, unresectable stage III or IV melanoma were randomly assi
260 In this phase I study, 90 patients with unresectable stage III or IV melanoma who were ipilimuma
261 il July 28, 2011, of patients (N = 245) with unresectable stage III or IV melanoma, at least 1 prior
263 atients with untreated or previously treated unresectable stage III or IV melanoma, without previous
264 ials of nivolumab in 440 adult patients with unresectable stage III or stage IV melanoma, who had bee
266 ctively analyzed all patients with nonuveal, unresectable stage III/IV melanoma treated with single-a
267 isplatin in chemotherapy-naive patients with unresectable stage IIIB to IV nonsquamous non-small-cell
269 cally confirmed BRAF(V600) mutation-positive unresectable stage IIIC or stage IV melanoma were random
270 ed 423 previously untreated patients who had unresectable stage IIIC or stage IV melanoma with a BRAF
273 ction (PTR) is recommended for patients with unresectable stage IV colorectal cancer (CRC) who presen
274 compared for 44 514 patients diagnosed with unresectable stage IV CRC from January 1, 1988, through
275 ribution of PTR to survival in patients with unresectable stage IV CRC over the past two decades in t
278 acebo, with similar safety, in patients with unresectable, stage III non-small-cell lung cancer.
279 udy, 418 patients with previously untreated, unresectable, stage III/IV, wild-type BRAF melanoma were
282 lation included 185 Australian patients with unresectable stages IIIC and IV melanoma referred from C
284 those patients who are at risk for having an unresectable tumor and who should be referred to a liver
286 utic strategy for management of symptomatic, unresectable tumors by somatostatin analogue therapy.
288 gnancy by imaging analysis for patients with unresectable tumors or who underwent neoadjuvant treatme
289 eatment modality that can selectively target unresectable tumors through optical activation of cytoto
290 e therapies is either to allow patients with unresectable tumors to become surgical candidates, provi
291 is demonstrating utility in the treatment of unresectable tumors where thermal ablation techniques ar
292 lected group of patients with conventionally unresectable tumors, ex vivo surgery can offer effective
296 atients with chemotherapy-naive, metastatic, unresectable uLMS were randomly assigned to gemcitabine-
297 ty in patients with metastatic or surgically unresectable urothelial carcinoma whose disease progress
300 ty to a definitive answer (ie, resectable or unresectable) when the reports were structured than when