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1 on elevates T(opt) when ambient substrate is unsaturated.
5 g process involving an alkyne, an alpha,beta-unsaturated acid chloride, which serves as both the alke
6 micals used in the synthesis of polyvinyl-co-unsaturated acids resins, pharmaceutics, and bio-degrada
8 creasing intensity ratio of lipids with less unsaturated acyl chains to the same type of lipids with
9 s to rationalize the preference of ACAT1 for unsaturated acyl chains, and provides insight into the c
11 carbonyl electrophiles to deliver a range of unsaturated alcohol coupling products under operationall
12 enzyme-catalyzed ester hydrolysis in giving unsaturated alcohol with an enantiomeric excess of >95%.
13 ne-catalyzed polymerization of olefins using unsaturated alcohols as chain-transfer agents has been d
14 significantly enhance the selectivity to the unsaturated alcohols compared to monometallic catalysts.
15 ation of alpha,beta-unsaturated aldehydes to unsaturated alcohols is a challenging class of reactions
16 eterogeneous catalysts, the formation of the unsaturated alcohols is thermodynamically disfavored ove
17 e factors that promote the adsorption of the unsaturated aldehyde via its C=O bond, most notably by e
19 (e.g., formaldehyde, acetone) and alpha,beta-unsaturated aldehydes (e.g., acrolein, crotonaldehyde) w
20 ble 1,3-dicarbonyl substrates and alpha,beta-unsaturated aldehydes afforded 1,2,4-trioxane derivative
21 ts demonstrate that especially saturated and unsaturated aldehydes and ketones contribute to the odor
24 limination to form thiol-reactive alpha,beta-unsaturated aldehydes, which then react with cysteine re
26 tions of cyclic carbon acids with beta,gamma-unsaturated alpha-keto esters and the chemical shift of
28 nyl phosphate as a catalyst, a wide range of unsaturated amides and thioamides underwent thiocyanatio
29 sical ring-closing metathesis of N-homoallyl-unsaturated amides or the dehydrogenation of amides, occ
30 es an overview of warheads-beyond alpha,beta-unsaturated amides-recently used in the design of target
32 ata allowed us to extract the information on unsaturated and hydroxylated acylcarnitine species, amin
34 A biosynthesis and elongation of mono-, poly-unsaturated and saturated fatty acids and enabled us to
35 trate (NO(3)) radicals were quantified, with unsaturated and saturated VOCs having oxidation lifetime
36 aturated APD moiety of lincomycin versus the unsaturated APD moiety of PBDs, providing molecules with
37 ults suggest that polyisoprenoids-even fully unsaturated-are not sufficiently good tunneling conducto
38 various arene diazonium salts to furnish 2,3-unsaturated aryl C-glycosides in moderate to excellent y
39 we also identified a series of noncanonical, unsaturated bile acids that were depleted in patients wi
42 approach that allows for the direct union of unsaturated building blocks with aryl aldehydes and othe
43 boxylic acid derived), several saturated and unsaturated C-4 alkylated coumarins were synthesized.
45 demonstrated mainly in addition reactions to unsaturated carbon-carbon bonds, allylic and propargylic
46 a little studied alpha-diazonium-alpha,beta-unsaturated carbonyl compound, is formed at low temperat
48 nantioselective hydroamination of alpha,beta-unsaturated carbonyl compounds for the synthesis of beta
49 that may be used to generate many alpha,beta-unsaturated carbonyl compounds in up to 81% yield and >=
51 he electrochemical deuteration of alpha,beta-unsaturated carbonyl compounds under catalyst- and exter
54 olamide and dithiol to yield an alpha,beta - unsaturated carbonyl moiety along the polymer backbone.
55 f an acyl group-derived enol to a alpha,beta-unsaturated carbonyl moiety, leading to N- and O-derived
57 labeling (CL) reagent based on an alpha,beta-unsaturated carbonyl scaffold has been developed for stu
58 vailable substrates into valuable alpha,beta-unsaturated carbonylated products including aldehydes, k
60 e formation of endocyclic enol lactones from unsaturated carboxylic acids in an one-pot procedure.
61 cting in concert to decarboxylate alpha-beta unsaturated carboxylic acids using a highly modified fla
62 The asymmetric hydrogenation of alpha,beta-unsaturated carboxylic acids using readily prepared bis(
71 s mainly of carba- and heteronucleophiles to unsaturated conjugated substrates can give different add
72 tteries because of a large atom utilization, unsaturated coordination, and unique electronic structur
75 sed enantioselective synthesis of alpha,beta-unsaturated cyclohexenones through a facially selective
76 results in densely functionalized alpha,beta-unsaturated delta-lactones featuring a CF(3)-substituted
77 the reaction is scaled up and the alpha,beta-unsaturated delta-lactones were converted to amino acid
78 -acetyl-lysine, we identified the alpha,beta-unsaturated dialdehyde 2-butene-1,4-dial (BDA) and its c
80 l-mediated reduction of several aromatic and unsaturated diesters, can be efficiently and regioselect
81 composed of egg SM, cholesterol, and either unsaturated dioleoyl PC (DOPC) or 1-palmitoyl 2-oleoyl P
84 zing aza-Claisen rearrangement of alpha,beta-unsaturated enals with cyclic vinylogous amides under ox
85 oorly coordinative groups such as alpha,beta-unsaturated enones, esters, lactones, and lactams as wel
88 ls to trisubstituted alpha-fluoro-alpha,beta-unsaturated esters both in racemic and, for the first ti
89 l t-butyldimethylsilyl group; (2) alpha,beta-unsaturated esters were generally more reactive than ter
90 ntermediates, both trisubstituted alpha,beta-unsaturated esters, beta-indole-substituted diazo esters
95 ght restricted to the fabA and fabB genes of unsaturated FA synthesis, but FadR overproduction marked
96 agy might help explain the known benefits of unsaturated FAs in countering the toxicity of saturated
97 and modulates autophagy, but the effects of unsaturated FAs such as oleate, which are also elevated
100 tunnel in FakB1 prevents the binding of cis-unsaturated FAs, which are instead accommodated by the k
101 e milk alternatives with healthier saturated/unsaturated fat balance for those in areas where milk su
103 ndations to decrease SFA and replace it with unsaturated fat should continue to the basis for healthy
104 arch has shown that replacement of SFAs with unsaturated fat, but not refined carbohydrate and added
106 unrestricted diet rich in carbohydrates and unsaturated fat, prolonged sedentary periods or limited
108 lycerides, resulting in higher proportion of unsaturated fats in SFF of powders with large lactose cr
109 und that neither high levels of saturated or unsaturated fats per se increased retinal leukocyte accu
112 massively expanded gene families involved in unsaturated fatty acid biosynthesis, DNA repair, photopr
113 iterpenes, oxidation/hydrolysis products and unsaturated fatty acid chains being the most significant
117 nthesized structurally diverse saturated and unsaturated fatty acid conjugated ASOs with a range of h
119 tissue (VAT) phospholipids, indicating lower unsaturated fatty acid incorporation into adipose tissue
120 eus from palmitoleic acid, the antimicrobial unsaturated fatty acid produced by most mammals, and tha
122 estricted presence (5-10% of surface fat) of unsaturated fatty acids (C18:1 and C18:2) in IF with hig
123 merase (Cti) an enzyme that converts the cis-unsaturated fatty acids (FAs) of the membrane lipids to
124 hat converts saturated fatty acids (SFAs) to unsaturated fatty acids (UFAs), at low temperatures.
126 ipidomic analysis showed increased levels of unsaturated fatty acids and decreased levels of saturate
127 k, which contains lower saturated and higher unsaturated fatty acids and demonstrated higher antioxid
131 ced by cows' diets; grazing pasture enhances unsaturated fatty acids in milk compared with conserved
133 -tolerant P. syringae, including increase of unsaturated fatty acids in the plasma membrane; a RNA po
134 ators of ruminal biohydrogenation of dietary unsaturated fatty acids may be explained by the effects
135 oleic acid attaches to ASBT, suggesting that unsaturated fatty acids may decrease ASBT's function via
136 fatty acid biosynthesis, and biosynthesis of unsaturated fatty acids showed significant differences a
138 These findings underscore the potential for unsaturated fatty acids to reduce ASBT function, which m
140 ls in saturated fatty acids rescued, whereas unsaturated fatty acids worsened, the alphaS phenotypes.
141 wn to be repressive, we show here that cis-2-unsaturated fatty acids, a rare chemical class used as d
143 osphatidylcholines, sphingolipids, saturated/unsaturated fatty acids, eicosanoids, and phospholipids.
145 d content, and especially omega-3 long chain unsaturated fatty acids, P. tricornutum exhibits a large
146 Multicereal showed the highest amount of unsaturated fatty acids, while Wholemeal and Rye scored
154 ferroptosis, while concomitantly decreasing unsaturated fatty acyl chains in membrane phospholipids
155 on, carbon-carbon double bond position(s) in unsaturated fatty acyl chains, and, in some cases, fatty
156 glycoprotein covalently modified with a cis-unsaturated fatty acyl group at a conserved serine resid
158 reactions using internal alkenes, among them unsaturated fatty ester (methyl oleate), to produce line
159 biochemical objectives-the total production, unsaturated fraction, and average length of fatty acids-
162 oline as well as for hydrogenation of common unsaturated functionalities, including ketone, alkene, a
163 tep transformation of N-protected alpha,beta-unsaturated gamma-amino amides into 5,5-disubstituted ga
165 s, revealing C=C locations for more than 200 unsaturated glycerophospholipids in bovine liver among w
168 two exolytic alginate lyases mainly cleaved unsaturated guluronic acid oligosaccharides to monomers.
170 contained ionizable lipids with low pKa and unsaturated hydrocarbon chains showed the highest amount
172 tive radical-trapping antioxidants (RTAs) in unsaturated hydrocarbons where both species are formed.
173 ectively reduce the imine bond in alpha,beta-unsaturated imine substrates to afford unsaturated amine
175 ncluding a 1,4-(bis)electrophilic alpha,beta-unsaturated ketenyl phosphonium species have been detect
176 tivation of aromatic systems with alpha,beta-unsaturated ketone and subsequent aldol condensation has
177 EA-soft enolization of the formed beta,gamma-unsaturated ketones and regioselective acylation with ac
180 and enantioselective synthesis of beta,gamma-unsaturated ketones that contain an alpha-stereogenic ce
181 nd finally the beta-thiolation of alpha,beta-unsaturated ketones to generate bis-vinyl sulfides.
182 othly with a collection of cyclic alpha,beta-unsaturated ketones, generating a new C-C bond and stere
185 a common method from the same nine-membered unsaturated lactam precursor, we developed conditions fo
188 strategy wherein phosphine oxides passivate unsaturated lead sites during perovskite crystallization
192 This study opens a door for high throughput unsaturated lipid analysis with minimal requirement for
194 lipids, primarily due to decreases in highly-unsaturated lipid species that contained 18:3 fatty acid
201 surface proteins and are composed of highly unsaturated lipids that increase membrane fluidity, exhi
202 ation of carbon-carbon double bonds (C=C) in unsaturated lipids to distinguish C=C location isomers r
205 generated damage to nucleic acids, membrane unsaturated lipids, and protein components has been show
207 stiffening effect on membranes populated by unsaturated lipids, such as 1,2-dioleoyl-sn-glycero-3-ph
209 igate the damage resistance of saturated and unsaturated liquid crystals (LC's) under a wide range of
210 RabGAPs control the uptake of saturated and unsaturated long-chain FAs (LCFAs) into skeletal muscle
212 rganic frameworks (MOFs) with coordinatively unsaturated metal sites are appealing as adsorbent mater
215 s re-cast as a surrogate of a coordinatively-unsaturated metalloenzyme active site, with utility for
216 arth's atmosphere, generates the four-carbon unsaturated methacrolein oxide (MACR-oxide) Criegee inte
217 ly key to bacterial survival in a variety of unsaturated microbial habitats, including leaf surfaces.
218 transformed to a single alkene product, and unsaturated moieties embedded within linear and heterocy
220 turated and unsaturated-show that completely unsaturated molecules transport charge faster than those
221 ng C-H bonds), nucleophiles (e.g., adding to unsaturated molecules), and transfer agents (e.g., deliv
222 that through the use of a complex bearing an unsaturated N-heterocyclic carbene (NHC) ligand, for the
224 esolve the anomeric configuration of the 3,4-unsaturated Neu5Ac derivatives through the synthesis of
226 ole grains where possible" (84%) and "Choose unsaturated oils and spreads and eat in small amounts su
228 reased ASBT function, whereas treatment with unsaturated oleic acid significantly reduced ASBT functi
229 he seed saturated (palmitic and stearic) and unsaturated (oleic, linoleic, and linolenic) FA were det
231 es, we found that BcelPL6 initially releases unsaturated oligosaccharides of a degree of polymerizati
233 e chemoselective hydrogenation of alpha,beta-unsaturated organic compounds, which cannot be achieved
235 l Co(III)-catalyzed annulation of alpha,beta-unsaturated oxime ether with alkyne has been reported.
237 C sp(2), sp or sp(3)), as well as by the C-C unsaturated partner that is used as a hydrocarbonation p
239 nerates, after proton loss, a coordinatively unsaturated Pd-OH species that can bind amine substrate
240 ence of a previously untapped group of short unsaturated peptides in the bacterial kingdom, suggestin
241 ooctane sulfonate (PFOS), hydrogen-PFOS, and unsaturated PFOS] appeared to be more bioaccumulative th
243 ng region of an opposite leaflet composed of unsaturated phosphatidylcholine (PC) and cholesterol.
245 ietary pattern representing higher levels of unsaturated phosphatidylcholines and phospholipid ethers
247 n double bond (C=C db) positional isomers of unsaturated phospholipids (PL) in tissue sections by use
248 cies present in the membranes, together with unsaturated phospholipids and cholesterol, can be used b
251 lateral segregation in a ternary bilayer of unsaturated PL/N-palmitoyl-D-erythro-sphingomyelin and c
252 ion reagent that allows functionalization of unsaturated PLs during the MALDI process via a laser-lig
253 ffinity of cholesterol was for the different unsaturated PLs, the more cholesterol stimulated lateral
255 directly characterizes transport through an unsaturated porous medium in three spatial dimensions at
256 he resulting sludge cake was affixed atop an unsaturated porous-medium column of glass beads to asses
259 elective 1,3-prototropic shift of beta,gamma-unsaturated prochiral isomers, under mild reaction condi
260 sing strategies are adopted to transform the unsaturated pronucleophilic precursors into the reactive
261 suggest an unconventional co-distribution of unsaturated PS and phosphatidylinositol 4-phosphate (PI4
264 d via C-H reductive elimination and features unsaturated Ru and Zn centers and an axial Z-type [ZnMe]
265 ts, the 'GAL-E' (organic) presented a higher unsaturated/saturated ratio than the 'GAL-T' cultivar (c
266 ngth-matched hydrocarbons-both saturated and unsaturated-show that completely unsaturated molecules t
267 ain open metal sites (OMS) or coordinatively unsaturated sites (CUS) or open coordination sites (OCS)
269 olayer curvature toward water is mediated by unsaturated, small-headgroup lipids and couples directly
271 xic microsites present in the rhizosphere of unsaturated soil is a key driver for mobilization and bi
272 lution inside anoxic microsites of primarily unsaturated soil, which may have implications on the mob
273 nts such as arsenic and uranium in irrigated unsaturated soils, accounting for 55% of the irrigated a
274 sphingomyelins (C34:0, C36:0, C38:0, C40:0), unsaturated sphingomyelins (C34:1, C36:1, C42:3), hydrox
275 ycosylceramides, lactosylceramides, or other unsaturated sphingomyelins (even if having an SFA base)
277 ive indication and perhaps suggests that the unsaturated spiroketal fragment might be crucial to indu
278 k of a metal-phosphido (M-PR(2)) group on an unsaturated substrate and proton transfer involving the
279 cis-Delivery of H(2) to the pai-system of an unsaturated substrate is the canonical course of metal c
280 tion, comparing the involvement of different unsaturated substrates as well as the different transiti
281 nsition metal-catalyzed hydrocarbonations of unsaturated substrates have emerged as powerful syntheti
282 of P-H bonds to alkenes, alkynes, and other unsaturated substrates in hydrophosphination and related
283 trocatalytic approaches to the activation of unsaturated substrates via reductive concerted proton-el
284 ycloaddition reaction involving all kinds of unsaturated substrates with metals such as Co, Ni, Ru, R
285 s, in the human respiratory system which has unsaturated surfactants as important components of lung
286 ctivity observed with nonspecially activated unsaturated systems can often be transposed to specially
288 t similar to DOPC because mobilities of both unsaturated tails confer a cone shape to DOPC, and PGPC
290 provides access to sterically congested and unsaturated tetrazoles, which are difficult to access by
291 s of compounds related to the degradation of unsaturated TGs due to ambient ozonolysis emerged with t
295 amples of cascade cyclizations of alpha,beta-unsaturated thioesters proceeding are reported, which pr
296 -organic frameworks featuring coordinatively unsaturated transition metal sites are relatively common
297 tudy the nature of multiphase ozonolysis, an unsaturated triglyceride, triolein, of the type present
299 components while factors composed of highly unsaturated triglycerides were linked to healthy AHEI co
300 nation of a chloride ion to a coordinatively unsaturated vanadium center within a cluster that bears