ライフサイエンスコーパス: unselected

1 A cohort of unselected 8th-grade school children (mean age 14 years)

2 ood was studied prospectively in a cohort of unselected 8th-grade schoolchildren established in 1995

3 Unselected adults with active cancer and a recent diagno

4 The public survey included unselected adults, whereas the patient survey captured i

5 A total of 2,098 unselected all-comer patients (50% with acute coronary s

6 The unselected AMC and ckit(+)AMC-treated mice demonstrated

7 arms: (1) normal saline control (n=14), (2) unselected AMCs (n=10), (3) ckit(+)AMCs (n=13), and (4)

8 ned in a murine myocardial injury model: (1) unselected AMCs, (2) ckit(+)AMCs, and (3) AMC-derived in

9 onnaire at baseline and 1 year later in 2693 unselected AMI patients from 24 hospitals enrolled in th

10 th rigorously defined s-AML or t-AML and 105 unselected AML patients.

11 an population and include all patients in an unselected and consecutive manner.

12 optimize the assay, validate the findings in unselected and diverse populations, and determine its po

13 enters without on-site cardiac surgery in an unselected and nationally representative population of t

14 l rate Temprid, and then reared progeny from unselected and selected strains.

15 this population-based cohort study, we used unselected annually updated data from Danish nationwide

16 birth cohort (n = 1074), assembled using an unselected antenatal sampling frame, participants were c

17 Eligible populations included unselected, asymptomatic individuals without known urina

18 ulting marker-selected stock outperformed an unselected benchmark stock in terms of hygienic behavior

19 onal methods to investigate rejection in 703 unselected biopsies taken 3 days to 35 years post-transp

20 ated our results in an independent set of 74 unselected biopsy specimens.

21 Verification was sought in an independent unselected birth cohort (BAMSE) constituting 3051 childr

22 ears) from the Infant Immune Study (IIS), an unselected birth cohort closely monitored for asthma for

23 FAIR (Food Allergy and Intolerance Research) unselected birth cohorts were established in 1989 and 20

24 allergic sensitization from two independent unselected birth cohorts, we identified latent classes w

25 Known pathogenic CNVs in unselected, but assumed to be healthy, adult populations

26 rol, cohort, and cross-sectional studies and unselected case series were eligible for inclusion.

27 nts were simultaneously attracted toward the unselected category response, indexing the degree to whi

28 cal and laboratory data from 749 consecutive unselected CD children diagnosed by national referral ce

29 Our ability to direct localization of unselected CD8 T cells into B-cell follicles using CXCR5

30 er B-cell follicles, we genetically modified unselected CD8 T cells to express CXC chemokine receptor

31 Here, we demonstrate that engineering unselected CD8 T cells to express CXCR5, a chemokine rec

32 array occur at a rate of >10(-3)/division in unselected cells.

33 es not adversely affect exercise capacity in unselected CHF patients.

34 to mothers with asthma (COPSAC2000 ) and 700 unselected children (COPSAC2010 ) were analyzed followin

35 This cross-sectional study of unselected children included 1185 participants in urban

36 Design: Unselected children with newly diagnosed and previously

37 pward than downward intensity deviants in 26 unselected chronic tinnitus subjects with normal to seve

38 Two independent studies, in unselected civilians (N = 22) and police recruits (N = 5

39 s was significantly higher in FR-CLL than in unselected CLLs at diagnosis (10.3% vs 1.1%, P = .004),

40 fter a median follow-up of 7.2 years, in the unselected cohort (n = 6,211) increasing exercise exposu

41 addition of vismodegib to gemcitabine in an unselected cohort did not improve overall response rate,

42 sequencing analyses of blood samples from an unselected cohort of 1005 children with IBD, aged 0-18 y

43 of DDX41-related myeloid malignancies in an unselected cohort of 1385 patients with MDS or AML.

44 ons of 85 orphan or understudied GPCRs in an unselected cohort of 51,289 individuals.

45 In a prospective study, an unselected cohort of 66,822 participants with and withou

46 e clinical course of atopic dermatitis in an unselected cohort of adolescents followed into adulthood

47 and type I sensitization prospectively in an unselected cohort of adolescents followed into adulthood

48 ults to predict overall mortality in a large unselected cohort of diabetic and nondiabetic patients.

49 s not been prospectively assessed in a large unselected cohort of fetuses with structural anomalies.

50 In a large adult-predominant unselected cohort of mainly relapsing CNS inflammatory d

51 th major adverse cardiovascular events in an unselected cohort of patients undergoing elective, nonca

52 to evaluate late toxicity and survival in an unselected cohort of patients who experienced relapse af

53 udies have shortcomings, we present a large, unselected cohort of patients who have undergone close m

54 ype testing and chromosomal microarray in an unselected cohort of sequential pregnancies showing feta

55 herefore, a prevention strategy targeting an unselected cohort of seropositive patients with acute re

56 barachnoid Aneurysm Trial in a retrospective unselected cohort of subarachnoid hemorrhage patients.

57 ures of patients from a large adult-dominant unselected cohort with mainly relapsing central nervous

58 f individual long-term registry data from an unselected cohort, novel anticancer therapies seem to be

59 In a nationwide unselected cohort, the performance of the RCRI was simil

60 hort, and 62% as a cumulative estimate in an unselected cohort.

61 cancer-related death for: (i) all patients ("unselected" cohort), and on the basis of (ii) classic cl

62 We present a 4-year study with 262 unselected consecutive high-risk episodes, prospectively

63 In RCT No. 2, a total of 154 unselected consecutive patients with cirrhosis and acute

64 In RCT No. 1, a total of 211 unselected consecutive patients with cirrhosis and acute

65 study was a multicenter prospective study of unselected consecutive patients with low rectal cancer r

66 g T1 and T2 mapping, compared with EMB in an unselected, consecutive patient cohort with suspected my

67 Unselected, consecutive, incident patients with pancreat

68 iated with reduced mortality also in a broad unselected contemporary population with HF and reduced e

69 ved multicellular structures not observed in unselected control populations within ~750 asexual gener

70 h DSM-IV OCD, a subset of their parents, and unselected controls, were genotyped with several differe

71 n born to mothers with atopic disease in the unselected COPSAC2010 cohort (adjusted HR = 0.39 [0.19-0

72 Replication was performed in the unselected COPSAC2010 cohort with follow-up until 5 year

73 ver the hazard ratio patterns present in the unselected data sets: The corrections overshot the targe

74 lence of pathogenic gene variants in a large unselected DCM population and determined the role of ele

75 with human HCMV-convalescent-phase sera from unselected donors confirmed the conserved antibody respo

76 illation risk haplotype) in a cohort of 1440 unselected Dutch SCA victims included in the Amsterdam R

77 ome measures were the prevalence of LS in an unselected EC population and the diagnostic accuracy of

78 stic accuracy of LS testing strategies in an unselected EC population.

79 k factors and incident severe AS in a large, unselected elderly population.

80 We analysed unselected emergency admissions to four Oxford Universit

81 pital trusts were those in England receiving unselected emergency admissions.

82 ing PD-1, has moderate efficacy in biomarker-unselected endometrial cancer.

83 In unselected estrogen receptor-positive/HER2-negative pati

84 hmia secondary variants can be identified in unselected exomes.

85 We study 20,360 unselected families containing index persons, their pare

86 s a reference group for APC mutations in the unselected FAP population, we used the UMD-APC database

87 lysis of WES data in a prospective cohort of unselected fetuses with structural anomalies shows the v

88 ling Test in a large sample of patients with unselected focal frontal (n = 60) and posterior (n = 30)

89 Cells analyzed were either unselected for a specific subpopulation or phenotypicall

90 population-based endometrial cancer cohort, unselected for age or family history, were analyzed to d

91 mother-child pairs from a US prebirth cohort unselected for any disease were studied.

92 mother-child pairs from a US prebirth cohort unselected for any disease.

93 peripheral-blood cells from 12,380 persons, unselected for cancer or hematologic phenotypes.

94 patients with CRC (oncology clinic cohort), unselected for familial risk.

95 tic variants with EOC risk from 15,437 cases unselected for family history and 30,845 controls and fr

96 ts with triple-negative breast cancer (TNBC) unselected for family history of breast or ovarian cance

97 Patients with TNBC (N = 1,824) unselected for family history of breast or ovarian cance

98 cumented metastatic prostate cancer who were unselected for family history of cancer or age at diagno

99 sent at high frequency in patients with TNBC unselected for family history of cancer.

100 g men with localized prostate cancer who are unselected for family predisposition is insufficient to

101 yelofibrosis and 252 637 population controls unselected for hematologic phenotypes.

102 heral-blood cells of 17,182 persons who were unselected for hematologic phenotypes.

103 tibility gene mutations in patients with CRC unselected for high-risk features (eg, early age at diag

104 older and had metastatic endometrial cancer (unselected for microsatellite instability or PD-L1), had

105 Patients unselected for PD-L1 expression received avelumab (10 mg

106 essing after platinum-based chemotherapy and unselected for PD-L1 expression received avelumab 10 mg/

107 LFIRINOX seems to be detrimental in patients unselected for tumor HA status.

108 mutants, as well as in atrial biopsies from unselected forms of human AF.

109 advanced or metastatic, HER2-positive, PD-L1-unselected gastro-oesophageal adenocarcinoma, with an Ea

110 r azithromycin confers a similar risk in the unselected general population is unknown.

111 s, but effectiveness has not been studied in unselected general populations unrestricted by region, f

112 RS) enables effective risk stratification in unselected glaucoma cases and modifies penetrance of the

113 In the unselected glaucoma population, individuals in the top P

114 We analyzed a cohort of 110 unselected HCV patients who started triple therapy from

115 NGS methods using (i) unselected HCV RNA (metagenomics), (ii) preenrichment of

116 Consecutive unselected HIV-infected adults in South Africa were syst

117 thousand six hundred ninety-five consecutive unselected ICU admissions during a six-month period in 2

118 nts in Africa (STAMP) trial, which recruited unselected (ie, irrespective of clinical presentation) a

119 We conclude that 1/30 unselected individuals harbor a pLOF mutation associated

120 e extent of familial clustering of MVP among unselected individuals in the community using current, m

121 itral valve prolapse (MVP) progression among unselected individuals in the community, including those

122 Genetic screening programs in unselected individuals with increased levels of low-dens

123 This cohort study included unselected infants born at NTT Medical Center Tokyo betw

124 f 872 nasal swabs collected biweekly from 47 unselected infants.

125 Median PFS in the unselected intent-to-treat population was 3.75 months wi

126 Among unselected intermediate- and high-risk patients, TAVR an

127 er compared with that in previously reported unselected IRD cohorts.

128 nding of the relevance of these cells in 100 unselected kidney transplant recipients followed prospec

129 cleotide composition existed in the initial, unselected libraries purchased from two different manufa

130 from each selected pool and compared to the unselected library.

131 The chickens are an unselected line descended from a commercial elite broile

132 ve line, while simultaneously maintaining an unselected line to serve as the Control.

133 skeletal phenotype frequency compared to 526 unselected lines (P < 0.0001).

134 nonmetastatic cell lines but contrary to the unselected metastatic cell population.

135 Vision screening of an unselected middle school population investigated and ana

136 a prospective birth cohort of 366 infants of unselected mothers, respiratory health was assessed week

137 Seventeen unselected MRSA-positive patients were identified in a c

138 mia and mortality was observed in our large, unselected multicenter cohort.

139 ic endophenotypes for schizophrenia in large unselected multigenerational pedigrees.

140 To generate a large number of unselected mutations, we immunized B1-8 H chain transgen

141 known respiratory virus-positive (n= 42) and unselected (n= 67) pediatric nasopharyngeal swabs using

142 ion DES, and newer generation DES in a large unselected national data set from the BCIS (British Card

143 are associated with improved outcomes in an unselected nationwide population of patients with HF wit

144 In an unselected nationwide population of patients with HF wit

145 No significant association was detected for unselected OC cases (OR, 1.74; 95% CI, 0.57-5.08; P = .2

146 e data suggest that first-line ibrutinib for unselected older adults with CLL is unlikely to be cost-

147 e the validation classified the 69.6% of the unselected original cases.

148 nvestigate coronary angiographic findings in unselected out-of-hospital cardiac arrest patients refer

149 ion NORd-Pas-de-Calais) study enrolled 4,184 unselected outpatients with stable CAD (i.e., MI or coro

150 The frequency of GBA mutations in unselected Parkinson's disease populations has not been

151 The estimated FH prevalence was 1:256 in unselected participants and 1:118 in participants ascert

152 from those in research settings, even in an unselected patient population in which oral failure was

153 omitinib was not superior to erlotinib in an unselected patient population with advanced non-small-ce

154 enefit to current EGFR-targeted agents in an unselected patient population, and highlight the need fo

155 wing to the impossibility of including large unselected patient populations in randomized clinical tr

156 frequency of related clinical phenotypes in unselected patient populations is not well established.

157 ate the long-term safety of ubrogepant among unselected patient populations.

158 (2+) ATPase (SERCA) inhibitor, on a panel of unselected patient-derived neurosphere-forming cells and

159 Unselected patients (N=1954) presenting to the emergency

160 atment response, sputum samples (n=124) from unselected patients (n=35) with sputum microscopy-positi

161 Over 14 months, all unselected patients admitted to an adult intensive care

162 o decrease with increasing length of stay in unselected patients admitted to ICUs in United Kingdom a

163 el data describing the procedure's safety in unselected patients are lacking.

164 ned acute myeloid leukaemia blast cells from unselected patients attending our UK hospital between Fe

165 cond-line treatment in oesophageal cancer in unselected patients does not improve overall survival, b

166 rior to the biolimus-eluting Nobori stent in unselected patients for target lesion failure at 1 year.

167 l Hyperplasia Study (PRODIGY) trial assessed unselected patients from tertiary care hospitals with st

168 Rituximab monotherapy (R-Mono) in unselected patients has shown a lack of durable remissio

169 g of 246 Staphylococcus aureus isolates from unselected patients in Thailand showed that 10 (4.1%) we

170 whom 126 patients were treated (23 FGFR mRNA-unselected patients in the dose-escalation phase and 103

171 In METREX, unselected patients in the modified intention-to-treat p

172 We prospectively enrolled unselected patients presenting to the emergency departme

173 ctive multicenter diagnostic study enrolling unselected patients presenting with suspected non-ST-seg

174 Unselected patients presenting with syncope to the ED we

175 ural administration of rectal indometacin in unselected patients reduced the overall occurrence of po

176 rta (Ao) ratio is associated with outcome in unselected patients referred for cardiac magnetic resona

177 In unselected patients treated for acute cholangitis in a l

178 Eight hundred ninety-two unselected patients treated intensively in the United Ki

179 aluation of the health status outcomes among unselected patients treated with TAVR is of critical imp

180 Among unselected patients undergoing PCI, GIB has a profound e

181 Unselected patients were enrolled at diagnosis of mCRPC

182 December, 2006 until June, 2008, molecularly unselected patients were recruited to a three-arm design

183 agents have been negative, but these were in unselected patients where it was unknown whether the tar

184 red with femoral access improves outcomes in unselected patients with acute coronary syndromes underg

185 focal brain lesions (n = 581), derived from unselected patients with acute ischaemic injury (mean ag

186 ygen has recently shown survival benefits in unselected patients with acute respiratory failure.

187 litaxel did not significantly improve PFS in unselected patients with advanced melanoma.

188 Data for 173,233 unselected patients with an AMI, including 33,503 patien

189 stopathologic assessment was conducted in 83 unselected patients with biopsy-proven NAFLD from a sing

190 Unselected patients with chest pain presenting at emerge

191 daptive pacing (versus fixed-rate pacing) in unselected patients with CHF does not improve peak exerc

192 In unselected patients with cirrhosis, who underwent succes

193 efinitive results of these long-term RCTs in unselected patients with cirrhosis.

194 on genes have a frequency of less than 1% in unselected patients with colorectal cancer.

195 We found that 30% of unselected patients with community managed asthma were c

196 lence and spectrum of these conditions among unselected patients with early-onset colorectal cancer (

197 eceptor (EGFR) tyrosine kinase inhibitors in unselected patients with head and neck squamous cell car

198 ur registry, we have analyzed a total of 500 unselected patients with HLH.

199 linical phenotype of PA in a large cohort of unselected patients with hypertension, consecutively ref

200 r clinical and duplex ultrasound assessment, unselected patients with intermittent claudication reque

201 alth-related quality of life after 1 year in unselected patients with intermittent claudication.

202 RET that produced a 10% overall response in unselected patients with lung cancers.

203 of SIRT in combination with chemotherapy in unselected patients with metastatic colorectal cancer ca

204 b, single-agent foretinib lacked efficacy in unselected patients with metastatic gastric cancer.

205 ct with the addition of SBRT to nivolumab in unselected patients with metastatic HNSCC.

206 ab compared with bevacizumab plus placebo in unselected patients with recurrent glioblastoma in this

207 ove outcomes in poor prognosis but otherwise unselected patients with SCCHN.

208 creased mortality when it is administered to unselected patients with septic shock.

209 of FFR use and its effect on outcomes among unselected patients with SIHD and angiographically inter

210 A prospective cohort of unselected patients with ST-segment-elevation myocardial

211 In this study of unselected patients with ST-segment-elevation myocardial

212 Use of SBRT with erlotinib for unselected patients with stage IV NSCLC as a second- or

213 rge study of prospective mutation testing in unselected patients with TC, molecular signature was ass

214 We analyzed data collected from consecutive unselected patients with UGIB from medical centers in 4

215 Among 2813 unselected patients, 447 (16%) had renal dysfunction (de

216 Of the 2,098 unselected patients, 73.1% were still alive after 10 yea

217 al, contemporary clinical practice cohort of unselected patients, improvement in health status after

218 sed in a long-term population-based study of unselected patients.

219 matic mutation landscape was indistinct from unselected patients.

220 paclitaxel did not result in improved PFS in unselected patients.

221 acy of NACT by extent of residual disease in unselected patients.

222 d the drugs provided insufficient benefit in unselected patients.

223 entification of surface autoantibodies among unselected people with new-onset focal epilepsy.

224 Compared with unselected peripheral blood mononuclear cells, CMV-CTLs

225 er yielded no benefit in the treatment of an unselected population and should not be used.

226 y was the high incidence of asthenopia in an unselected population and that refractive status per se

227 population equivalent to IQ > 147) and 3,253 unselected population controls.

228 , post-mortem, whole-body MRI at 1.5 T in an unselected population of fetuses (</=24 weeks' or >24 we

229 ated with improved mortality/morbidity in an unselected population of HFmrEF and HFpEF patients.

230 response associations with incident AS in an unselected population of older individuals, and together

231 vascularization on long-term prognosis in an unselected population of patients with and without T2DM.

232 ested in therapeutic trials starting from an unselected population of patients with metastatic melano

233 In an unselected population of patients with nonsquamous NSCLC

234 (Pd/Pa vs iFR in an Unselected Population Referred for Invasive Angiography

235 opulation of the VERIFY2 (Pd/Pa vs iFR in an Unselected Population Referred for Invasive Angiography)

236 was not more effective than PVI alone in an unselected population undergoing atrial fibrillation abl

237 omplex has an excellent safety profile in an unselected population with advanced CKD and merits furth

238 ival and cannot be recommended for use in an unselected population with advanced oesophagogastric ade

239 In an unselected population, the putatively pathogenic genetic

240 We described therapy discontinuation in an unselected population-based cohort of adults with metast

241 lation distribution of intelligence and 8172 unselected population-based controls.

242 lation distribution of intelligence and 3253 unselected population-based controls.

243 argeted sequencing data derived from a large unselected population-based patient cohort with full cli

244 track disease evolution from diagnosis in an unselected population-representative incident cohort.

245 ing patients after TAVR in the context of an unselected population.

246 meaningful benefit might be restricted in an unselected population.

247 e IPFSG classification was confirmed in this unselected population.

248 and its association with exercise in a large unselected population.

249 Particularly in unselected, population-based cases, considering putative

250 luated several progression algorithms in our unselected, population-based cohort for risk prediction

251 alyzing prognostic factors and outcome in an unselected, population-based cohort.

252 Simons Simplex Collection and MSSNG) and two unselected populations (IMAGEN and Saguenay Youth Study)

253 value of large, deeply phenotyped cohorts of unselected populations coupled with NGS data.

254 Decoding from unselected populations enables a read-out of motivationa

255 tiangiogenic agents may not be beneficial in unselected populations of patients with GBM.

256 lish the general prevalence of asthenopia in unselected populations of school-aged children.

257 Multicenter data from large unselected populations on patients' radiation doses duri

258 of ABI testing in primary care populations, unselected populations, and asymptomatic populations; th

259 es to streamline registries and the study of unselected populations, and identifying ways to improve

260 Its performance in unselected populations, including different age groups,

261 dentally detected PE ranges from 1% to 4% in unselected populations, with higher rates among hospital

262 pLI decreases IQ by 2.6 points in autism and unselected populations.

263 ng for major CVD outcomes in primary care or unselected populations; and the effect of treatment on g

264 Unselected prodrug-converting activities were mostly una

265 However, it is unclear in unselected "real-world" patients if sources drive persis

266 risingly found that it also carried multiple unselected rearrangements elsewhere in its genome.

267 xplain less variability for yield G x E than unselected regions, indicating that improvement by breed

268 te IGH@ V-D-J sequences can be computed from unselected RNA-seq reads with results equal or superior

269 A novel finding in this large, unselected sample from high-quality regional registries

270 ce of intelligence in the normal range in an unselected sample of 3414 individuals, which is comparab

271 ciated with measured cognitive ability in an unselected sample of 4854 participants of European ances

272 conclusions about lateralization based on an unselected sample of the population and laterality asses

273 ifferences in intelligence in an independent unselected sample.

274 In unselected samples, untargeted metagenomics had excellen

275 be informed by penetrance estimates of HH in unselected samples.

276 In unselected SCA victims from the community, common geneti

277 is similar to colorectal cancer, supporting unselected screening of EC for LS.

278 A prospective unselected series of 20 patients with symptomatic or asy

279 lis major muscles of modern fast-growing and unselected slow-growing chickens.

280 ficantly less susceptible to Temprid SC than unselected strains.

281 LOH tracts revealed that they too contained unselected structural alterations more often than contro

282 Of the 384 unselected students approached in Grades 6-9, 353 partic

283 Two years after enrollment, an unselected subgroup of 188 children were enrolled into l

284 dy exhaled breath samples were taken from an unselected subset of adults with severe asthma from the

285 In contrast, unselected susceptible WCR neonates expressed a large nu

286 Further including 20% of unselected symptomatic individuals in the public sector

287 neous CAR-T cell products were prepared from unselected T cells.

288 Here, we isolated TCR libraries from unselected thymocytes and upon reexpression of these ran

289 s and treatment burden data of 56 eyes of 54 unselected treatment naive patients diagnosed with exuda

290 al cells clustered differently compared with unselected tumor and normal cells.

291 The expression of the HP in unselected VH4-34 cells was assessed by deep sequencing.

292 sistant, eCry3.1Ab-selected and susceptible, unselected, whole WCR neonates which fed on seedling mai

293 likely to harbor anti-brain antibodies than unselected women of child-bearing age (10.5 vs 2.6%).

294 m Simon Simplex Collection and plasma of 653 unselected women of child-bearing age for anti-brain ant

295 We provide evidence that unselected women with these thrombophilias have an incre

296 muscle were studied among selected (FP) and unselected (WP) Atlantic salmon lines that were reared t

297 Twelve patients responded to therapy with unselected young TILs (according to Response Evaluation

298 anoma were prospectively assigned to receive unselected young TILs versus CD8(+)-enriched TILs.

299 Thirty-four patients received unselected young TILs with a median of 8.0% CD4(+) lymph

300 s to prepare, future studies should focus on unselected young TILs.