ライフサイエンスコーパス: unusual

1 s of adenosine deaminase characterized by an unusual 1,3-diazepine nucleobase.

2 earth (RE) MOFs that are constructed from an unusual 12-connected pai-stacked pyrene secondary buildi

3 d inhibits tumor cell migration, contains an unusual 2-acyl-4-hydroxy-3-methylbutenolide in addition

4 cinnapeptin as a cyclic depsipeptide with an unusual 2-methyl-cinnamoyl group.

5 The mutational profile is unusual; ~50 different missense mutations have been iden

6 action of substituted N-allylanilines via an unusual 6-endo process has been developed.

7 r cross-presented by APC and demonstrate the unusual ability of dendritic cells to process stable pro

8 rstanding the functional significance of the unusual abundance of opsins found in many arthropod spec

9 e was diminished, probably because it had an unusual affinity for the Z-disc and mutant DNAJB6.

10 Additionally, unusual all-C-metallacycles like metallacyclopentynes Cp

11 Oysters are unusual among bivalves in that they possess chambers, of

12 ymilk) was frequent among patients (15%) but unusual among controls (2%; P < .025).

13 roton at the remote site in 3 facilitates an unusual anaerobic pathway for phenol nitration.

14 The MoO(2)F(3)(-) chain has a very unusual and complex chain structure; a single chain cont

15 etization of the ordered state permits these unusual and rarely observed manifestations of Onsager's

16 der stress biology to be relevant only under unusual and threatening conditions, we conceive of it as

17 En route to the target, unusual and unexpected strain release driven transformat

18 The dipeptide self-assembles through an unusual and unprecedented two-step process as elucidated

19 hes for specialized fungi and is affected by unusual and yet not so well-documented mechanisms of alt

20 This work opens up an unusual approach in analytical chemistry for developing

21 lent organic framework (COF) by reacting the unusual approximately T-shaped 5,10,15-tris(p-aminopheny

22 les were applied to existing structures with unusual arginine-guanine recognition, we found that the

23 Here, we explored mechanisms contributing to unusual aspects of regulation of the lac operon.

24 16-18 carbons long, S. japonicus synthesizes unusual "asymmetrical" glycerophospholipids where the ta

25 g-induced ion migration, accounting for many unusual attributes and thus performance in perovskite-ba

26 artic protease features, whereas others have unusual attributes, including the nepenthesin loop of pl

27 d to delineate the pivotal character of this unusual B cell population.

28 acellular pathogen Listeria monocytogenes is unusual because it carries all the genes for both pathwa

29 nital tract infections in humans and mice is unusual because the majority of antigen-specific CD8 T c

30 These motors exhibit unusual behavior, in that all four diastereomeric states

31 the tethered Ant-l-Kyn dipeptide to form the unusual benzazepine scaffold in 1.

32 xy-d-myo-inositol was inaccessible due to an unusual beta-elimination reaction, wherein the azide ani

33 We reveal an unusual beta-keto acid (N-methyl-2-aminobenzoylacetate)

34 uted 2-deoxystreptamine ring that carries an unusual bicyclic eight-carbon dialdose moiety.

35 rization of this group of proteins and their unusual biochemical properties warrant further studies i

36 earch, such as cancer, as they often display unusual biological features.

37 wing on l-carnitine, E. limosum excreted the unusual biological product norcarnitine as well as aceta

38 s act as biological metamaterials, eliciting unusual biological responses.

39 hermally active landscape is reported via an unusual biomarker distribution consistent with the prese

40 nch of life, including species with a highly unusual body plan and a range of unique adaptations to t

41 e that this class of nanoribbons should have unusual bonding topology and metallicity.

42 of viral polymerase activity that possesses unusual broad-spectrum activity against diverse paramyxo

43 tation branches are resolved that display an unusual broken symmetry.

44 iple length scales are exploited and predict unusual bulk-scale properties for protein-based material

45 onomer-dimer equilibrium associated with its unusual C-terminal extension.

46 ant advancement in our understanding of this unusual Caenorhabditis species.

47 Herein, an unusual canonic-like behavior of the c lattice parameter

48 ic, and rheological experiments, indicate an unusual carbohydrate-aromatic CH-pai bonding that promot

49 We present an unusual case of a patient with hepatocellular carcinoma

50 Here, we report the unusual case of intraoperative evidence of spontaneously

51 3CL M(pro) possesses an unusual catalytic dyad composed of Cys(145) and His(41)

52 Rupture of RAA is an extremely unusual cause of acute flank pain and haemodynamic insta

53 tes of highly modified fatty acids that bear unusual chemical functionalities.

54 An unusual chemical stability was observed for sterically u

55 y of colloids with complex architectures and unusual chiroptical and chemical properties.

56 Recent epigenomic studies have revealed the unusual chromatin landscapes that are present in oocytes

57 High entropy alloys (HEA) are an unusual class of materials where mixtures of elements ar

58 o highly versatile edge states, including an unusual class that emerges from the type-II degeneracies

59 This unusual clinical course is consistent with a contributio

60 ecent inbreeding to select for recessive and unusual coat colors may have concentrated this relativel

61 m de-mixing of elastic monopoles to a zoo of unusual colloidal crystals formed by high-order multipol

62 ection but high RET to both partners, a very unusual combination.

63 lowing bilateral lung transplantation, as an unusual complication.

64 uring dehydration processes and catalysed by unusual condensation domains.

65 icant attention in electronics, due to their unusual conduction properties stemming from their inhere

66 POFs) with pure organic surfaces may provide unusual confinement effects for organic substrates in ch

67 g bulky chiral organic cations to exhibit an unusual confluence of exceptionally low melting temperat

68 mentation of this protocol, which allows the unusual construction of C(sp(2))-O bonds using commercia

69 The enzyme has an unusual cooperative reaction mechanism involving an acti

70 exotine A and exotine B, which comprise the unusual coumarin-cyclohepta[b]indole ring system, have b

71 ns the pyrimidine ring of ectoine through an unusual covalent intermediate, N-alpha-2 acetyl-l-2,4-di

72 However, the synthesis of unusual crystal phases of noble metals still remains a g

73 The nature of the unusual CW EPR spectrum has been re-evaluated in light o

74 cluding Naumovozyma castellii, which have an unusual Dicer and a conventional Argonaute that are both

75 e vinylogous aldol reaction to introduce the unusual dichloromethyl substituent, a completely diaster

76 It contains an unusual dihydronaphthyridine core.

77 An unusual dinuclear rhodium complex with the anionic 2-mer

78 Other unusual diverticula heading in a caudal direction have n

79 how that the human Smc5/6 complex recognizes unusual DNA configurations and uses the energy of ATP hy

80 us type I-D Cas10d large subunit exhibits an unusual domain architecture consisting of a Cas3-like HD

81 ezoelectric phases in CuInP(2)Se(6), forming unusual domain walls with enhanced piezoelectric respons

82 Characterized by an unusual double chromosome and frequently carrying numero

83 We demonstrate an unusual dual-mode solid-state thermal rectification effe

84 -quadruplex units, while another features an unusual duplex hairpin structure adjoined to two stacked

85 he structure of lincomycin A consists of the unusual eight-carbon thiosugar core methyllincosamide (M

86 unneling microscopy/spectroscopy to discover unusual electronic coupling to flat-band phonons in a la

87 inorganic-ion-based valence band provide an unusual electronic platform with localized states for el

88 ons play an important role in the materials' unusual electronic states, the nature of these fluctuati

89 We attribute the unusual electronic structure of these compounds to the m

90 inference is that the release of the highly unusual encapsulated water droplet creates a strong ther

91 the biochemical processes underpinning this unusual enzyme's wide-ranging antiviral activity.

92 by Jakobiec and associates, the data on this unusual epibulbar lacrimal gland lesion remain sparse.

93 heoretical calculations demonstrate that the unusual evolution of the unit cell for CaBa(1-x)Pb(x)Zn(

94 This work provides an unusual example of mutual stabilization between metal cl

95 Therefore, ATRX and MYCN represent an unusual example, where inactivation of a tumor-suppresso

96 The present cages represent unusual examples of enantiopure tetrahedral cages of squ

97 This unusual expression pattern is mostly dictated by differe

98 ng an intense current interest driven by its unusual extreme magnetoresistance (XMR) property and the

99 Here, we describe an unusual family of spirotetronate polyketides, called str

100 ten are associated with the incorporation of unusual fatty acids.

101 superfamily, capable of generating a highly unusual Fe(IV)Fe(IV)=O oxidation state, known to be resp

102 formation of a bridging N(2) ligand with an unusual Fe-Ct(N2)-Fe angle of 150 degrees (Ct(N2) = cent

103 prior to or at the time of symptom onset, an unusual feature that has enabled widespread transmission

104 e quantum phases of matter with a variety of unusual features arising from their topological characte

105 Here, we investigated the unusual features of KPC-2 that enable this resistance.

106 are toxic for the expression system or show unusual features that cannot be easily programmed in liv

107 The hydrogen phase diagram has several unusual features which are well reproduced by density fu

108 /pathways and provided evidence for multiple unusual features, including uncoupling of carotenoid and

109 etoplastid flagellates are known for several unusual features, one of which is their complex mitochon

110 loviridae members, TSPV1 has numerous highly unusual filaments decorating its surface, which can exte

111 Prior studies revealed unusual flexibility in the coupling between multidrug bi

112 l morphology of the bimetallic NPs, which is unusual for a GRR, to the presence of the native oxide s

113 ck connectivity as found in DNA but which is unusual for the free neutral base pairs.

114 (PrAMPs) are cationic antimicrobial peptides unusual for their ability to penetrate bacterial membran

115 Our findings provide documentation of an unusual form of directed HAT and are of crucial importan

116 heterocumulene moieties can allow access to unusual free carbene coordination geometries given the p

117 er transition metal dichalcogenides provides unusual freedom in the selection of components for verti

118 Here we describe an unusual fusion between cA4-activated CRISPR ribonuclease

119 This work shows that highly unusual gene origin processes can give rise to novel gen

120 Our findings highlight an unusual genetic architecture of MN, with four loci and t

121 infrequent naive B cell precursors and with unusual genetic features that may be subject to host reg

122 tallo-borospherenes represent a new class of unusual geometry that has not been observed in chemistry

123 es the degree to which the observed data are unusual, given the null hypothesis or other test hypothe

124 Unusual glycan epitopes identified on CD11b/CD18 include

125 is not only important for defining how these unusual GPCR modulators function in disease, but also pr

126 An unusual greater reactivity of phosphonous propionic acid

127 rasites such as Toxoplasma gondii possess an unusual heme biosynthesis pathway whose enzymes localize

128 dinate high spin Fe(III) hemoprotein with an unusual heme-binding arrangement that involves a co-axia

129 iffraction, which reveals the presence of an unusual heteroatomic metal planar fragment Ge@Pd(3).

130 Mesotrypsin is an unusual human trypsin isoform with inhibitor resistance

131 diffusion coefficients further support this unusual hydrogen-bonding interaction.

132 ma environment at moderate disease, multiple unusual immune cell phenotypes emerge and amplify with i

133 cant levels of its precursor polyprenol, are unusual in eukaryotic cells.

134 patterns of these 33 transcripts were highly unusual in five respects: 1) All long-wavelength and sho

135 The protein is unusual in its poor secretion from cells and its intrace

136 knowledge of the network structure, which is unusual in practice.

137 The yeast plasma membrane is unusual in that it may have a high lipid order, which co

138 xample of metal/ligand proton tautomerism is unusual in that the position of the equilibrium can be c

139 species-specific associations with PPEs are unusual in the oligotrophic ocean.

140 nchiopod crustacean taxa currently absent or unusual in the region although they exist in the arid zo

141 This unusual independence is further supported by molecular d

142 human dose, best-in-class potential, and an unusual inhibition mode by binding the IDO1 heme-free (a

143 Their unusual inhibitory properties are due to (a) Leu(15) in

144 e hydration method that is facilitated by an unusual interception of an electrophilic intermediate by

145 The unusual interprotein Co-S bond was characterized by X-ra

146 An unusual inverse phase transition sequence from a BCC pha

147 the current state of the art) and in CT (an unusual key step in this approach) has the potential to

148 rectly with these iodine acids, but forms an unusual kind of interaction with them within a few picos

149 The unusual kinetic properties of the PHDs, in particular a

150 nchor poses synthetic challenges such as the unusual kinetically controlled (1 -> 2)-beta-oligomannan

151 enes that operates with ATP and GTP exhibits unusual kinetics toward F6P, as it appears to have an ex

152 under large magnetic fields have revealed an unusual Landau level (LL) structure(1-3), distinct from

153 To understand if this unusual lateralized behavior may have coevolved with gen

154 ntrinsic Chern quantum phases owing to their unusual lattice geometry and breaking of time-reversal s

155 ng network forms the structural basis of the unusual LH1 redshift.

156 hHV5 may be the first DNA virus with such an unusual life history.

157 stic fibrosis patients were found to produce unusual lipodepsipeptides containing a unique citrate-de

158 The drug showed unusual long-lasting effects, as rats gradually stopped

159 of the cyclohexyl substituents result in an unusual low-spin square planar Co(II) complex, which is

160 compound is a highly frustrated magnet with unusual magnetic phase behaviours.

161 osomes whose inverted cylinders orient in an unusual manner, forming hoops that are noncircular.

162 ome of the most effective strategies rely on unusual materials such as liquid metals, nanowires, and

163 spensions of hard colloids, leading to their unusual mechanical properties.

164 This mutant has an unusual mechanism as it depletes normal-functioning DNM2

165 rt-cycle models to describe and explain this unusual mechanism have been proposed based on known CLC

166 eurexins, except for neurexin-1gamma, via an unusual mechanism.

167 Yeast Sfh5 is an unusual member of the Sec14-like phosphatidylinositol tr

168 TANGO1 has an unusual membrane helix organisation, composed of one mem

169 MRAP2 and its homolog MRAP1 have an unusual membrane topology and are the only known eukaryo

170 inogenes contains a significant SBP pool, an unusual metabolite that is elevated during growth on xyl

171 ticularly intriguing because they exhibit an unusual metal-to-metal transition.

172 arks, hard-shelled prey specialists, possess unusual microarchitecture that controls tooth erosion in

173 ysical properties of PGCCs, as well as their unusual migratory persistence.

174 for land-intensive bioenergy will require an unusual mix of policies and incentives that encourage ap

175 udies indicate that amide reduction obeys an unusual mixed-order rate law which is proposed to origin

176 Altogether, these data reveal an unusual mode by which neuroligin splicing controls synap

177 The SL receptor has an unusual mode of action.

178 Computational studies reveal an unusual mode of enantioinduction by the remote chiral ce

179 lecules yield coherent frequency combs whose unusual mode structure may find applications in metrolog

180 ty beyond simple ON/OFF switching, including unusual modes of gene regulation, and highlighting an un

181 c individuals tended to successfully imitate unusual movement kinematics while autistic individuals t

182 hat HEK-sKlotho is uniquely modified with an unusual N-glycan structure consisting of N,N'-di-N-acety

183 a-OTf coordination motifs, in addition to an unusual "naked" [Ga](+) ion, are found.

184 esis is presented to transform CO(2) into an unusual nano and micron dimensioned morphology of carbon

185 ct can be further oxidized to a structurally unusual Ni(2) (N(2) H(2) ) species; this releases N(2) i

186 the underlying physics responsible for their unusual nonlinear behaviour.

187 Once considered unusual, nucleocytoplasmic glycosylation is now recogniz

188 the C-terminal end, with SpxA1 containing an unusual number of acidic residues.

189 Recently, two unusual objects have been found to be closely orbiting S

190 rk Al site to expand its coordination to the unusual octahedral AlO(4) N(2) environment.

191 rAssphage proteins were predicted, including unusual ones such as giant RNA polymerase polyproteins.

192 o react appropriately and perceive precisely unusual or dangerous conditions in the real world.

193 microbiological culture may fail to identify unusual or fastidious organisms and can misrepresent rel

194 Nevertheless, atypical or unusual organisms reported in short-read amplicon sequen

195 The unusual origin of the selectivity is the dynamically ret

196 In 2012, an unusual outbreak of urban malaria was reported from Djib

197 Mycobacterium tuberculosis has an unusual outer membrane that lacks canonical porin protei

198 securinega family of alkaloids containing an unusual oxazabicyclo[3.3.1]nonane core, is described.

199 nto the steps of the catalytic cycle of this unusual oxidation reaction, a series of mechanistic expe

200 di-GMP)(2)-sigma(WhiG) complex, revealing an unusual, partially intercalated c-di-GMP dimer bound at

201 r the discovery of new archaeal viruses with unusual particle morphologies and gene content.

202 To elucidate this unusual performance, we conducted detailed photophysical

203 We explain this unusual phenomenon by the lack of fast particles in acti

204 C. jejuni possesses an unusual phospholipidome that is highly dynamic in respon

205 ovide evidence that polyketides support this unusual photosynthetic partnership.

206 Ru(3+) and Ru(4+) in light of their range of unusual physical properties.

207 (2)-fixing (diazotrophic) microorganisms and unusual physiological adaptations, combined with diagnos

208 ticular, the pentanuclear complexes adopt an unusual planar "bow tie" configuration.

209 ylneryl diphosphate, which is cyclized by an unusual plastidial terpene synthase (LfTPS1) into the ch

210 s to how to elucidate the mechanism of these unusual polymerizations as well as their entire strain m

211 nt in edible pine seeds and that exhibits an unusual polymethylene-interrupted structure.

212 excess blue light alongside the chloroplast unusual positioning1 (chup1) protein.

213 e DCLs was observed, which was induced by an unusual predatory action of the capsule on specific imin

214 formation of the complex to coordinate this unusual PRF mechanism.

215 opic studies support the involvement of this unusual process.

216 oallotropes are important nanomaterials with unusual properties and promising applications.

217 nderstanding the mechanisms underlying these unusual properties and the structures of their correspon

218 es with bending rigidity of a few kT exhibit unusual properties and they are the focus of theoretical

219 evelopmental blocks may be attributed to the unusual properties of bnAb variable regions, such as pol

220 l efforts have been made to explain the many unusual properties of dense hydrogen, including a rich a

221 While the unusual properties of fluorous materials are well establ

222 A fundamental understanding of the unusual properties of water remains elusive because of t

223 d thin film in the presence of gold exhibits unusual properties, acting as a new physicochemical dime

224 They display several unusual properties, such as specificity for aggregated f

225 -adenosyl-l-methionine (SAM) enzyme with the unusual property that addition of SAM to the [4Fe-4S](1+

226 The unusual radical-based organic chemistry of nucleotide re

227 this bimolecular reaction sheds light on the unusual reaction dynamics of Huckel aromatic systems and

228 perfamily known to catalyze some of the most unusual reactions in biology.

229 As a result, unusual rearrangement of 1,3-oxazinoquinolines to form e

230 of aromatic polyketide natural products via unusual redox tailoring reactions that appear to defy bi

231 upied perovskite lattice, which explains the unusual regenerative properties of these materials.

232 We identify an unusual regime of ultrafast nonlinear dynamics in which

233 The same unusual regioselectivity of addition was observed with m

234 It exhibited an unusual regiospecificity, cleaving apocarotenoids solely

235 to the success of this transformation is an unusual remote functionalization via chain walking to th

236 Signatures of correlated motion suggest unusual repulsive interactions between the water molecul

237 animal-derived antibodies have at least one 'unusual residue'.

238 ainst a prostate cancer antigen had several 'unusual residues' (rare somatic hypermutations, rSHM, wi

239 vision, movement of meiotic chromosomes, and unusual restitution mitosis in tapetum cells.

240 cobalt-carbon bond homolysis reaction in an unusual reversal of the heterolytic chemistry that was d

241 In this report, we show how an unusual ring contraction process can be harnessed for TD

242 Here we report observations of an unusual, ring-shaped ultraviolet ('blue') nebula and the

243 The data reveal an unusual robustness of ESCs against mitotic perturbants a

244 crete a suite of central metabolites and two unusual secondary metabolites, rosmarinic acid and azela

245 revealed four-coordinate Fe centers with an unusual "seesaw" geometry.

246 s originate from a high-energy state with an unusual sequence of band population.

247 a scaffold but also inhibits ERK7 through an unusual set of contacts that displaces nucleotide from t

248 ansition from XS to the DB anions XS(-), the unusual shortening of the internuclear Si...N distance i

249 We noticed unusual SIM-SUMO interfaces in a previously reported NMR

250 ate, anticoagulant therapy for thrombosis at unusual sites is generally accepted, but the optimal the

251 Venous thrombosis rarely occurs at unusual sites such as cerebral, splanchnic, upper-extrem

252 her mammals, specifically those that exhibit unusual sleep states, may lead to advances in our unders

253 an unexpectedly robust autonomous clock with unusual spatiotemporal characteristics in core and nonco

254 exposed to several hours of experience with unusual spatiotemporal patterns.

255 Caenorhabditis bovis is a particularly unusual species that has been isolated several times fro

256 resulted in N-C bond activation to give the unusual spiro-heterocyclic compound (5).

257 st bacterial lineages in the compositionally unusual sponge microbiome were not known to synthesize b

258 ystems that combine high oxygen content with unusual stability.

259 ine, but not propofol, is known to induce an unusual state known as "dissociative anaesthesia").

260 This nanoalloy exhibits unusual structural patterns.

261 -bonded organic framework (HOF) undergoes an unusual structural transformation after solvent removal

262 homology modeling analyses suggest that the unusual structure of ComGC is compatible with helical fi

263 Because of its unusual structure, apramycin is not susceptible to the m

264 Despite its unusual structure, Trkin encodes a functional minus end-

265 sCOFs) are being widely studied due to their unusual structure/property relationships.

266 chemists for more than a century with their unusual structures and high chemical reactivity(1).

267 Weyl semimetals exhibit unusual surface states and anomalous transport phenomena

268 r Asian species Boesemania microlepis has an unusual swim bladder with a slightly restricted anterior

269 19, reports have emerged of children with an unusual syndrome of fever and inflammation.

270 As from nucleases, extensive pairing to some unusual target RNAs can trigger miRNA degradation.

271 imulators are of rapidly growing interest as unusual therapeutic platforms, i.e., bioelectronic medic

272 ectivity, suggesting that they might display unusual thermomechanical properties.

273 the amide backbone of CTA is assembled in an unusual thiotemplated pathway involving the cooperation

274 ysis of two IDT derivatives yielded a highly unusual three-dimensional packing of the conjugated back

275 e-rich DNA sequences that spontaneously form unusual three-dimensional structures known as G-quadrupl

276 This review is focused on the treatment of unusual thrombotic manifestations as reported in the mos

277 rbonyl or nitrile, respectively, consists of unusual Ti(OPr(i))(4)-mediated Knoevenagel-type condensa

278 eq (scRNA-seq) studies suggested that it was unusual to see more than one isoform being produced from

279 l four amino acid sactionine macrocycles, an unusual topology for this compound family.

280 The unusual topology of the FlhB/SctU helices creates a loop

281 Here, we describe unusual trace fossils found in marginal-marine, storm- a

282 So, lead foreign body took an unusual trajectory impacting the globe and finally lodgi

283 lants contains a substantial fraction of the unusual trans fatty acid 16:1(Delta3trans) or 16:1t.

284 initio and DFT) were used to rationalize the unusual trans stereoselectivity for 6b, and a keto-enol

285 e labeling experiments, a mechanism for this unusual transformation is proposed.

286 Mechanistic studies for this unusual transformation suggest that the reaction operate

287 n starting material and features a number of unusual transformations (such as rearrangements, bromocy

288 -alkenylnitrone and an aryne to access these unusual transient rearrangement precursors.

289 ture and coordination chemistry including an unusual tridentate coordination effect of 1,2-diphenylet

290 tive deficit in two individuals, and various unusual tumors in one individual.

291 In an unusual twist, human cytomegalovirus co-opts the antivir

292 with the angular overlap model yields rather unusual U-O(ArO) and U-N(tacn) bonding parameters for th

293 ive shape and charge complementarity and the unusual utilization of an antibody N-linked glycan.

294 ediate state conductivity contributes to the unusual versatility of KCNQ1, which can function either

295 Unusual voltage-sensor domains with asymmetric linkages

296 h SspE provides protection against phages in unusual ways: (1) SspE senses sequence-specific PTs by v

297 This unusual wetting behavior is contrary to the conventional

298 The underlying mechanism is structurally unusual, with the loss of part of the alpha1 subunit tra

299 mately 21 million Americans, is irregular or unusual work schedule hours occurring after 6:00 pm.

300 Surgical correlation (n = 4) revealed unusual yellow discoloration of the bowel (n = 3) and bo