ライフサイエンスコーパス: unusually high

1 Median age was unusually high (11.5 years) compared with that in histor

2 n approximately 35-kb circular DNA genome of unusually high A/T content (>86%) that is replicated by

3 We hypothesized that the mobilities of unusually high absolute values are caused by the cross-l

4 We anticipate that these unusually high activities, despite still being too low f

5 engths (0-500mMNaCl), but it also reveals an unusually high activity and stability under alkaline con

6 2 (BIN1) Src homology-3 (SH3) domain with an unusually high affinity (Kd 24 nm).

7 -binding motif PxxxPR, which is required for unusually high affinity binding.

8 The alphaX ligand binding domain has an unusually high affinity for carboxyl groups, with KD at

9 ndicated that A. fulgidus RbcL2 possesses an unusually high affinity for oxygen (Ki=5 microM); O2 is

10 In addition, AS8 exhibits an unusually high affinity for the 16S ribosomal RNA, chara

11 of the Acm1 degron sequences results from an unusually high affinity interaction with the substrate r

12 In particular, the unusually high affinity of marine and terrestrial AOA fo

13 We propose that the unusually high affinity of O1 and O4 to their targets in

14 trast, the second LIP5 MIT module binds with unusually high affinity to a novel MIM element within th

15 structural adaptation of NamPT, providing an unusually high affinity toward Nam, necessary to maintai

16 ed NMDA receptors and that bind glycine with unusually high affinity.

17 ith water ice particles, it accounts for the unusually high albedos of the other satellites orbiting

18 s Shale-type deposits, and resulted from the unusually high alkalinity of Cambrian oceans.

19 r on gels ( approximately 60 kDa) due to the unusually high amount of bound negatively charged dye, w

20 elin membrane, which ensheaths axons, has an unusually high amount of cholesterol.

21 We detected unusually high amount of shared identical-by-descent (IB

22 Diversity was unusually high and the time to the most recent common an

23 ng 5 cases of debilitating neuropathy and an unusually high angioedema rate.

24 Importantly, some compounds exhibited unusually high antisickling activity despite moderate ef

25 the transition state, is responsible for the unusually high ( approximately 5 years) reaction half-li

26 Finally, we observed unusually high association rate constants for the intera

27 Activity with dihydropterin-6-aldehyde was unusually high at 0 degrees C.

28 l model for OR promoter recognition in which unusually high AT content, a unique epigenetic signature

29 r contrast to homologous AAA domains, has an unusually high ATPase activity and forms a hexamer in so

30 We found that Ubc6 has an unusually high basal activity that does not require stro

31 ecting extra-large zeolites because of their unusually high basicity combined with their large size a

32 ve blue-green bones and other tissues due to unusually high biliverdin concentrations-a phenomenon ca

33 and stereochemical diversity, exhibiting an unusually high bond-forming efficiency as well as high s

34 However, there are unusually high bone marrow transplant (BMT) rejection ra

35 of the APOE3 Christchurch (R136S) mutation, unusually high brain amyloid levels and limited tau and

36 Finally, we localize an unusually high 'burst-phase' of HDX in the large tetrame

37 (e.g., Rh/ReOx, Rh/MoOx, Ir/VOx) demonstrate unusually high C-O scission activity at moderate tempera

38 m mechanical calculations indicate that this unusually high capacitance may be attributed to a negati

39 bricated from the prepared carbons exhibited unusually high capacitance per unit surface area (>30 mu

40 , such as exhibiting novel protein folds and unusually high carbohydrate affinity, and ability to pot

41 atriciarum xylanase NpXyn11A, which displays unusually high catalytic activity and is one of the few

42 plain why the Neocallimastix enzyme displays unusually high catalytic activity.

43 Synaptic vesicles contain unusually high cholesterol, but the exact role of choles

44 on between carbon fiber and CO2 molecule for unusually high CO2 uptake and resistive sensing.

45 gest that if Nosema spp. are contributing to unusually high colony losses in recent years, the mechan

46 lower than that of the other arrestins, the unusually high concentration of ARR1 in rods would favor

47 RI shedding defect, there was nonetheless an unusually high concentration of functional TNFRI at the

48 sterone and androstenedione were measured in unusually high concentrations (1.6-12 and 7.8-40 ng/g we

49 H5N1 avian influenza viruses (HPAIV) present unusually high concentrations in serum of proinflammator

50 The petal wax was found to contain unusually high concentrations of C(22) and C(24) fatty a

51 In the tumor microenvironment, unusually high concentrations of extracellular adenosine

52 .4 microseconds at 5 kelvin) are obtained at unusually high concentrations.

53 ucture reveals features that can explain the unusually high conductance of Slo channels and how contr

54 In surface-supported bilayers, MelP5 forms unusually high conductance, equilibrium pores at peptide

55 ison exons are likely to contribute to their unusually high conservation and contrast with the dispen

56 However, unusually high contact resistance has been observed acro

57 of Cl- from the nucleus may result from its unusually high content of "excess" DNA that imposes an i

58 erived from HS oligosaccharides, we found an unusually high content of GlcN residue in a recently pur

59 l-trans-retinol provides a rationale for the unusually high content of PE and its long-chain unsatura

60 alyze sequences of spidroin NTDs and find an unusually high content of the amino acid methionine.

61 ll alpha-helical hydrophobic protein with an unusually high content of valine residues.

62 Unusually high copy numbers of approximately 10,000 in O

63 including at least one parent and child, had unusually high copy numbers of HHV-6 DNA per milliliter

64 nd, fus3Delta cells were found to exhibit an unusually high correlation between mother and daughter c

65 entification of sets of adjacent probes with unusually high correlation between the individual interg

66 aying surprising water and air-tolerance and unusually high coupling rates in dilute conditions.

67 he data provide additional insights into the unusually high cross-link density found in mature beaks.

68 This difference is a major contributor to unusually high CRP-mediated activation of cddP.

69 bimorph thermal actuators that bend with an unusually high curvature, ~900 m(-1).K(-1) over a wide t

70 atellites because its slow rotation produces unusually high daytime temperatures and water ice sublim

71 and theoretical studies suggested that this unusually high degree of catenation stems from the secon

72 tertiary propargylic C-H substrates with an unusually high degree of functional-group tolerance, thu

73 positive for viral infection and exhibits an unusually high degree of genomic methylation compared to

74 nome architectures are mosaic, reflecting an unusually high degree of horizontal genetic exchange in

75 ticular, with real data there tends to be an unusually high degree of maximum clique overlap.

76 S in combination with cryo-TEM confirms this unusually high degree of order (chi(SAXS) = 82%) and sho

77 selections have been observed to possess an unusually high degree of secondary structure.

78 t generates the toxin mycolactone display an unusually high degree of sequence similarity, implying t

79 The antibody genes had an unusually high degree of somatic mutation.

80 for interconversion of 1-Li aggregates were unusually high (DeltaG(double dagger) ca. 9 kcal/mol for

81 The cerebral vasculature meets the brain's unusually high demand for oxygen and glucose by providin

82 asmic reticulum (ER) and are likely to place unusually high demands on the resident chaperones and fo

83 mounts are denatured even in the presence of unusually high denaturant concentrations involving a com

84 tes demonstrates that motif co-occurrence in unusually high densities is essential for optimal DCC re

85 This includes unusually high densities of butchered tortoise and wild

86 equencing was performed for a family with an unusually high density of lung adenocarcinoma with avail

87 equences revealed 16 genomic regions with an unusually high density of rapidly evolving genes.

88 he sperm flagellum, where it is expressed at unusually high density.

89 tal hearts are unexpectedly asymmetric, with unusually high dGTP and GTP levels compared with those i

90 methyl carbonate anions together induce the unusually high diastereoselectivity.

91 hydes gives tetrasubstituted dioxolanes with unusually high diastereoselectivity.

92 t from layer 10 neurons, respond with tonic, unusually high discharge rates (>150 spikes/s).

93 750 to approximately 635 Myr ago, indicating unusually high dissolved phosphate concentrations in the

94 p and that Hepatocystis parasites display an unusually high diversity and prevalence in epauletted fr

95 Our results reveal an unusually high diversity of floral volatiles among popul

96 structural features, all orthologs share the unusually high DNA binding affinities and low catalytic

97 olar molecule with no H-bonding ability, the unusually high efficiencies of dPMP insertion are ascrib

98 arge microcrystals up to 200 mum across show unusually high emission that is not observed for limited

99 hly reduced redox states that correlate with unusually high Enemark-Feltham numbers.

100 Decreased need for sleep, unusually high energy, and increased goal-directed activ

101 ms: elevated mood, decreased need for sleep, unusually high energy, increased goal-directed activity,

102 Finally, vis-UV MCD spectra show an unusually high-energy Fe(II) --> alphaKG pi* metal-to-li

103 that the hydrogen atom transfer reaction has unusually high entropic demand, which results in substan

104 ly, the compound binds in the groove with an unusually high equilibrium constant.

105 heir chemical stability, predictability, and unusually high excitation-emission differential.

106 nuclear speckles, with chromosome regions of unusually high expression located at the apex of chromos

107 T conv cells had unusually high expression of PD-1 and the IL-33 receptor

108 (-) reacts with O(2) to form a quasi-stable, unusually high-extinction flavin hydroperoxide species t

109 egans and human genomes, suggesting that the unusually high factor association at HOT regions may be

110 ingers palpation technique was noted to have unusually high failure rates.

111 ng that CoVs with intact ExoN replicate with unusually high fidelity.

112 ries, as well as studies of populations with unusually high fish consumption (e.g., the Seychelles),

113 ified a set of up-regulated transcripts with unusually high fold changes in the CLL samples, several

114 birthdates called for induction appear with unusually high frequency among employees who were draft

115 oup A KIR haplotype and the HLA-C1 ligand to unusually high frequency in the Japanese, who provide a

116 ducator of C1-specific NK cells, has reached unusually high frequency in the Yucpa.

117 Anti-PL-7 was found at an unusually high frequency in this group of Japanese patie

118 to end-stage renal disease (6 of 14) and an unusually high frequency of cardiac (8 of 14) and/or neu

119 e protein data bank, our analysis reveals an unusually high frequency of cysteine pairings relative t

120 record in Europe and was associated with an unusually high frequency of reassortments between H5 HPA

121 or speed in the racehorse has resulted in an unusually high frequency of the C-variant (g.66493737C/T

122 The unusually high frequency of the Raman band for the C(4)=

123 er of SNP sites in these categories revealed unusually high genetic distances between the two most di

124 The unusually high glycan density on the gp120 subunit limit

125 Dopant 1 exhibited an unusually high helical twisting power, which is signific

126 ates by synthesizing novel polyhydrides with unusually high hydrogen-to-metal ratios.

127 humans than in other vertebrates but appears unusually high in flies and especially low in nematodes.

128 arotenoid levels in these outliers were also unusually high in the lens and in the peripheral retina.

129 Remarkably, an unusually high in-plane Fermi velocity up to 1.5x10(6) m

130 The authors detected an unusually high incidence of cases of medically attended

131 Our previous observations of unusually high incorporations of acrylates in copolymeri

132 re dependence of loop residue reactivity was unusually high, indicating that conformational changes i

133 CO geometry is nonlinear as indicated by the unusually high intensity of the Fe-C-O bending vibration

134 This study reveals that the unusually high intra-specific variation of volatile terp

135 1) and 0.23 s(-1), respectively, yielding an unusually high K(D) of 1.6 mM.

136 PanK-III enzymes have an unusually high Km for ATP, are resistant to feedback inh

137 known MYOD1 enhancers, and one displayed an unusually high level of 5-hydroxymethylcytosine in a qua

138 One explanation may be an unusually high level of convergent and parallel evolutio

139 g of the Fab part of rhuMAb suggest that the unusually high level of glycation of lysine residue 49,

140 : during 2009 in the Northern Hemisphere, an unusually high level of influenza virus activity over th

141 lysis showed that the proximate cause was an unusually high level of intracellular unincorporated iro

142 These antibodies all exhibit an unusually high level of somatic mutation, presumably owi

143 ide further support for a model in which the unusually high level of variability in NKT cell number a

144 he ribosomal E-, P- and A-sites, there is an unusually high level, 15%, of +1 ribosomal frameshifting

145 ent of eyes from donors age 48 and older had unusually high levels (66.3 +/- 15.1 ng) of macular caro

146 systems, orange carrots are characterized by unusually high levels of alpha-carotene in addition to b

147 cells expressing these variants accumulated unusually high levels of alpha1 as rings in N(alpha)-ace

148 Furthermore, the prevalence and unusually high levels of antimitochondrial antibodies (A

149 We suggest that despite the unusually high levels of ANXA5 in bundles, it does not p

150 Human and mouse HSCs had unusually high levels of ascorbate, which decreased with

151 neocortical neurons may be characterized by unusually high levels of energy metabolism.

152 Since 2015 both lineages have shown unusually high levels of epidemic activity, the reasons

153 The H. pylori species exhibits unusually high levels of genetic variation between strai

154 fer a tool for studying genomes that sustain unusually high levels of heterochromatinization.

155 The presence of unusually high levels of macular carotenoids in older do

156 ve enhancers in close genomic proximity with unusually high levels of Mediator binding, as measured b

157 We observed unusually high levels of nonsynonymous polymorphism in t

158 Tannat berries have unusually high levels of polyphenolic compounds, produci

159 being possibly advantageous, as indicated by unusually high levels of population differentiation, lon

160 Unusually high levels of recombinant A1AT were expressed

161 polymerases as one potential explanation for unusually high levels of replication fidelity.

162 the appearance of outliers; rare cells with unusually high levels of sasA expression, having increas

163 These genes also exhibit unusually high levels of segregating nonsynonymous polym

164 TGF)-beta (but not myostatin), which induces unusually high levels of TGF-beta pSmad3 in resident sat

165 rmations, which allows for the generation of unusually high levels of the cis-isomer by irradiation w

166 nt and its high rate of turnover necessitate unusually high levels of transport into the cilium.

167 tion entropy for ion transport, but manifest unusually high, liquidlike ionic conductivities (e.g., 1

168 rinsic property of CAP-Gly likely due to its unusually high loop content and may be required for its

169 Also identified in two samples displaying unusually high lytic gene expression was a novel rLCV ci

170 ccumulate an intracellular polysaccharide of unusually high M(r).

171 The unusually high measured hydraulic diffusivity of 2.4 x 1

172 cture of six out of seven chromosomes and an unusually high metal accumulation in leaves, which remai

173 used a mutation accumulation study to see if unusually high microsatellite mutation rates contribute

174 nning nano- through milliseconds reveals its unusually high mobility, both free and assembled on poly

175 The causes of the unusually high mortality in the 1918 pandemic were not e

176 We demonstrated that S. pyogenes has an unusually high mRNA turnover rate, with median and mean

177 However, the protein has an unusually high native-state heat capacity, and consequen

178 variants in a rhesus macaque that developed unusually high neutralizing antibody titers to SIVmac239

179 mmonia levels, is always acidic even for the unusually high NH3 levels found in Beijing (pH = 4.5) an

180 III) peroxide intermediate 2, which exhibits unusually high nucleophilic reactivity.

181 It possesses both unusually high nucleotide incorporation rates and high-e

182 ng overlap significance if a gene set has an unusually high number of annotations.

183 This issue also includes an unusually high number of cancer-related databases and ot

184 the agent of Q fever in humans, contains an unusually high number of conserved, selfish genetic elem

185 ponents of the T3S apparatus that contain an unusually high number of cysteine residues compared to o

186 winter of 2003-2004 in the UK and caused an unusually high number of deaths in children.

187 /411/2002-like(H3N2), was associated with an unusually high number of fatalities in children.

188 peculiar core oligosaccharide composed of an unusually high number of hexuronic acids containing beta

189 unique binding configuration, PBP-1 forms an unusually high number of hydrogen bonds (14) with the ph

190 This hypothesis seems to be supported by the unusually high number of M >or= 8 earthquakes occurring

191 roto-Calepineae Karyotype (n = 7) through an unusually high number of pericentric inversions.

192 e substitution within helix 4 resulted in an unusually high number of severely transport-defective mu

193 ith a common root structure that contains an unusually high number of terminal alphaGal-Gal moieties.

194 Mycobacterium tuberculosis genome harbors an unusually high number of toxin-antitoxin (TA) systems.

195 ycobacterium tuberculosis genome contains an unusually high number of toxin-antitoxin modules, some o

196 by disulfide bonds but nevertheless keeps an unusually high number of unpaired cysteines in its secre

197 .78-kb) 5' untranslated region (UTR) with an unusually high number of upstream AUGs (uAUGs), i.e., 64

198 ndifferentiated spermatogonia accumulated in unusually high numbers as early as 10 d after birth, whe

199 tasis in evolution has resulted in taxa with unusually high numbers of primitive characters.

200 These abnormalities resulted in an unusually high OC number, which is consistent with a rec

201 Unusually high occipital Abeta deposition is associated

202 in occipital lobe (lvPPA-high), representing unusually high occipital uptake compared to other region

203 This unusually high occupancy was verified experimentally, th

204 to collagen sequences highlights regions of unusually high or low stability, and these regions often

205 Rod regions show unusually high oxidation levels.

206 he heme-bound ligand, which accounts for its unusually high oxygen affinity (222 microm(-1)).

207 cifically interact with host genes that have unusually high p300 association within the gene body.

208 viruses, which cause disease in humans, have unusually high pathogenicity.

209 nza virus appeared, but it has not exhibited unusually high pathogenicity.

210 The MPER has an unusually high percentage of tryptophan residues that li

211 The atomic-scale origin of the unusually high performance and long-term stability of wu

212 artment to the plasma membrane, resulting in unusually high permease activity at the cell surface.

213 from other leptosporangiate ferns, achieving unusually high photosynthetic capacities through amphibi

214 erimental studies with CO2 have revealed its unusually high physical solubility in these media.

215 Glu468 in the active site contribute to the unusually high pK(a) value, 10.5, of Cys461.

216 eads to excellent electrocatalytic activity, unusually high poison tolerance, and reliable stability

217 d, intrinsically disordered polypeptide with unusually high polyproline type II helix propensity.

218 E1 of the small ubiquitin-like modifier has unusually high populations in both ordered and disordere

219 /bulk oxidation state, which may explain the unusually high potential stability of the resulting ISE.

220 This unusually high precursor frequency of clonal CD4 T cells

221 ently, the overexpression of VCC leads to an unusually high proportion of cotyledons with high-comple

222 sesses specific interneuronal equipment with unusually high proportion of CR+ interneurons, what migh

223 f allergen-specific patches consisting of an unusually high proportion of surface-exposed hydrophobic

224 s noted that the autoantibodies possessed an unusually high proportion of the IgG3 isotype in contras

225 rs of nine well-recognized phyla but also an unusually high proportion of three candidate divisions (

226 HA-IV subgroups appeared in 2015 and 2017 in unusually high proportions (13.1% and 14.4%, respectivel

227 inal aspect is manifest by the appearance of unusually high pyrophosphorolysis activity by the T4 DNA

228 ics provides a plausible explanation for the unusually high quantum yield of 40% for the primary isom

229 sidue at the protein surface that imparts an unusually high quantum yield of photoreduction.

230 mal insulation, removing the requirement for unusually high radiogenic heat production to achieve cru

231 Cryptosporidium hominis TS-DHFR exhibits an unusually high rate of catalysis at the TS domain, at le

232 GNN and NCC-GNN codon doublets, for which an unusually high rate of G to C and C to G transversions w

233 ional rate across diverse tumor types and an unusually high rate of loss of heterozygosity, has the s

234 ion, this backpropagation also results in an unusually high rate of rise of membrane potential at the

235 ination, though they are characterized by an unusually high rate of switching and by atypical substra

236 Replication forks also appear to stall at an unusually high rate throughout schizogony.

237 at pluripotent stem cells are not subject to unusually high rates of genetic or epigenetic alteration

238 Unusually high rates of Plasmodium sporozoite infections

239 iption of the specific mechanisms that allow unusually high rates of recombination without deleteriou

240 ain the gigantism of the double coconut than unusually high rates of seed size increase.

241 transcription factor overexpression induces unusually high rates of transcription and that sustainin

242 ing further evidence that the chicken has an unusually high recombination rate.

243 s ferrooxidans is a blue copper protein with unusually high redox potential and acid stability.

244 and adjacent amino acid sites, although the unusually high reduction potentials of the adjacent Fe-S

245 Baseline MPOD in enrolled subjects was unusually high relative to an age-matched control group

246 her mammalian ocular microbiomes but with an unusually high representation of bacteria from the famil

247 Bartonellae have unusually high requirements for heme, which is their onl

248 s demonstrate that light-weight materials of unusually high resistance to structural damage from shoc

249 control of constitutive signaling, and their unusually high resolution enabled a structure-based camp

250 The unusually high resolution of these structures that makes

251 th a differential mobility analyzer (DMA) of unusually high resolution.

252 heir genes pass through a temporary phase of unusually high responsiveness to oocyte reprogramming fa

253 This is supported by the unusually high rigidity of the Arg(10) side chain and it

254 a showed that soccer players in Italy had an unusually high risk of amyotrophic lateral sclerosis (AL

255 is judged by the endocrinologist as being at unusually high risk.

256 Incarcerated youth are an unusually high-risk cohort with numerous unmet medical a

257 ensity in all RLFS-positive genomes revealed unusually high RLFS densities in herpesvirus genomes, wi

258 in the Persian/Arabian Gulf (PAG) withstand unusually high salinity levels and regular summer temper

259 ttributed to wind changes associated with an unusually high sea level pressure (SLP) pattern over the

260 these bimetallic electrocatalysts exhibit an unusually high selectivity for the formation of multi-ca

261 mechanistic investigation suggests that the unusually high selectivity may be due to the catalyst's

262 ons were evaluated as a means to explain the unusually high selectivity observed at room temperature.

263 r experiments show that these nanopores have unusually high sensitivity (0.65 nA/A) to extremely smal

264 in the tubercle bacillus contributes to the unusually high sensitivity of M. tuberculosis to isoniaz

265 rogenitor cells from a patient that exhibits unusually high sensitivity to erythropoietin with concom

266 are localized by tRNAs and short regions of unusually high sequence similarity.

267 We infer that the unusually high set point of virus carriage in P. falcipa

268 ackgrounds after treatment with 2-ME created unusually high signal-to-noise ratios.

269 tern USA, which causes Lyme borreliosis with unusually high spirochaetaemia.

270 cted bicyclic peptide antagonist exhibits an unusually high stability in vivo and subsequently deciph

271 rise the domain-domain interface crucial for unusually high stability of gammaD-crystallin.

272 role in establishing the high Eox/sq and the unusually high stability of the anionic semiquinone stat

273 e identification of a set of frameworks with unusually high stability toward water vapor.

274 edly gave rise to fulleroid derivatives with unusually high stability.

275 biochemistry and whole-body physiology with unusually high statistical power.

276 DFT calculations suggest an explanation for unusually high stereoselectivity.

277 s, suggest essential elements underlying its unusually high substrate specificity.

278 This frequency is unusually high, suggesting an imidazolate character of t

279 nce fluctuations play a critical role in the unusually high Tc of PuCoGa5.

280 l spectra an N5-type spectrum is observed at unusually high temperature (indicating a significant cha

281 The prepared LBL films also revealed unusually high temperature resilience up to 500 degrees

282 SrRu2 O6 exhibits unusually high-temperature magnetic order, with antiferr

283 corresponding cyclononadienyl anion requires unusually high temperatures (120 degrees C), and computa

284 ve out of seven species that were exposed to unusually high temperatures exhibited significant decrea

285 In addition, TDP-43 demonstrated an unusually high tendency to aggregate, a property intrins

286 The recent observation of unusually high thermal conductivity exceeding 1000 W m(-

287 e folds into a monomolecular quadruplex with unusually high thermal stability and unique optical prop

288 on of intramolecular i-motif structures with unusually high thermal stability.

289 the Q(D) site are discussed, in light of the unusually high thermodynamic stability of MSQ(D).

290 Si nanowires were recently shown to have an unusually high thermoelectric figure of merit.

291 yos, the DSSA reagent permitted detection of unusually high thiol levels in the zebrafish chorion.

292 s of bilaterian Shakers and channels with an unusually high threshold for voltage activation.

293 r a bisphenol A (BPA) exposure study who had unusually high total BPA concentrations.

294 uding 1T-TaSe2, 1T-TaS2 and 1T-TiSe2 exhibit unusually high transition temperatures to different CDW

295 strategy has been established for achieving unusually high triplet levels for bipolar molecules (E(T

296 O2 due to their reactivity with CO2, as well unusually high viscosities in both the neat and complexe

297 Unusually high viscosities observed for suspensions of n

298 congenital Zika syndrome retrospectively by unusually high ZIKV-specific antibody titers.

299 Here, we leverage the unusually high Zn(II) concentration in beta-cells to dev

300 We conclude that the unusually high Zp activity level in AGS cells is due to