ライフサイエンスコーパス: unwanted

1 that unlike typical profilins, PRF1 prevents unwanted actin assembly by strongly inhibiting both F-ac

2 able to focus on a complex task and inhibit unwanted actions or interfering information (i.e., inhib

3 to understand what mechanisms exist to curb unwanted activation.

4 emic exposure of cancer therapies can induce unwanted adverse events.

5 However, the unwanted aggregation of the light-absorbing nanoparticle

6 -cell genome during CSR and SHM, AID induces unwanted (and sometimes oncogenic) mutations at numerous

7 compared to the analyte levels, to generate unwanted artifact signals in the MS spectrum.

8 thology/pedagogy, and best practices against unwanted autonomous machine behavior.

9 ess is suggested as a therapeutic target for unwanted aversive memories.

10 n is often required to spectrally un-mix the unwanted background signals.

11 elopment of strategies to reduce the load of unwanted bacteria is a fundamental challenge in industri

12 an unhealthy motor-like system containing an unwanted beta-oscillation spiral attractor is controlled

13 Unwanted beta2-blockade risks causing life-threatening b

14 erages bulk data as a constraint and reduces unwanted bias towards expressed genes during imputation.

15 plex templates in DNA libraries, introducing unwanted biases.

16 PE RNA-seq data, a key step that adjusts for unwanted biological and technical effects that can bias

17 roles in the CNS ranging from the removal of unwanted biomolecules to intercellular communication to

18 cells may offer a new target to prevent this unwanted bone.

19 nces (defect density, temperature, etc.) the unwanted bulk state will conduct in parallel to the topo

20 long list of hits with many citations being unwanted by the user.

21 olymers to be made from elemental sulfur, an unwanted by-product of the petrochemicals industry.

22 Nitrous oxide (N2O) is an unwanted byproduct during biological nitrogen removal pr

23 ) and water (H(2) O) contaminants introduce unwanted byproducts from side reactions that greatly aff

24 G base transversions, with reduced levels of unwanted C-to-W (W = A or T) and indel mutations.

25 a net negative energy balance while avoiding unwanted cardiovascular side effects.

26 -concordant treatment decisions and minimize unwanted care.

27 ve surgery may contribute to this problem of unwanted care.

28 ellular pathway by which pathogens and other unwanted cargoes are degraded.

29 terial RNA-seq library preparation to remove unwanted cDNA from 16s ribosomal rRNA without increasing

30 egulated or highly expressed, it can lead to unwanted cell death.

31 on (UTR), thereby ensuring a dual control of unwanted cell death: at the level of p53/CEP-1 and at th

32 n neurodegenerative diseases without causing unwanted cell growth and migration, genes regulating gro

33 for tissue-derived eosinophils can result in unwanted cell or ribonuclease activation, leading to poo

34 ating developmental paths that often lead to unwanted cell types.

35 The elimination of unwanted cells by apoptosis is necessary for tissue morp

36 gn or damaged cells; however, the removal of unwanted cells does not always require an adaptive immun

37 of control can be used to selectively remove unwanted cells from a Split GAL4 expression pattern or t

38 environment and by shielding germ cells from unwanted cellular interactions that can compromise their

39 ing that conjugation can effectively prevent unwanted central effects.

40 ppresses pathological pain but also produces unwanted central side effects.

41 a source of future outgassing and exacerbate unwanted changes in physical and chemical properties.

42 e of reference electrodes, and show that the unwanted changes in the reference potential are not uniq

43 analysis ensures product consistency with no unwanted changes to the protein.

44 We avoid unwanted charge current shunting by the low resistive NM

45 several tissue types to identify potentially unwanted chemical effects that could limit the therapeut

46 reaction range and also naturally suppresses unwanted chemical reactions in hybrid trapping experimen

47 e to mechanical damage or deteriorate due to unwanted chemical reactions with the surrounding agent.

48 erly measured or omitted from studies due to unwanted chemical transformations that occur during samp

49 conclude that Ub chains mark GPCRs and other unwanted ciliary proteins for recognition by the ciliary

50 therapeutic enzymes was effective to remove unwanted circulating small biochemical(s)/substrates, an

51 s are powerful genome engineering tools, but unwanted cleavage at off-target and previously edited si

52 Numerous strategies to reduce unwanted cleavage have been devised, but all are imperfe

53 Unwanted clots lead to heart attack and stroke that resu

54 rmation, and neocortical inhibition prevents unwanted co-activation between overlapping memories.

55 eed to reduce emissions from both wanted and unwanted combustion, discovery of this state points to p

56 rial in order to reduce or eliminate certain unwanted components, is a common winemaking practice.

57 il and in food, in reducing the formation of unwanted compounds (acrolein and hexanal), and in contra

58 ry control may underlie deficits in stopping unwanted compulsive behaviors in the disorder.

59 s ubiquitous and widely considered to be the unwanted consequence of a noisy nervous system.

60 formation on biotic or abiotic surfaces has unwanted consequences in medical, clinical, and industri

61 Soot emissions in combustion are unwanted consequences of burning hydrocarbon fuels.

62 To minimize unwanted consequences, environmentally friendly approach

63 e associated lack of specificity can lead to unwanted consequences, most notably an enhanced suscepti

64 tegration method for the region and removing unwanted contributions.

65 h other and from other paralogues to prevent unwanted crosstalk(3).

66 ructure-activity-relationships (SARs) of the unwanted CYP3A4 induction and the desired HBV capsid inh

67 role to stabilize the retinoid receptor from unwanted degradation and signal additional modification

68 anical factors and offer guidelines to avoid unwanted degradation happened to the framework.

69 mproving the reaction efficiency by reducing unwanted degradation pathways available to Selectfluor.

70 tems and highlight the ability to dissociate unwanted delta, kappa1, and alpha2 actions from analgesi

71 hey can act as a mechanical barrier to avoid unwanted dendritic growth of lithium through the cell.

72 We now show that the formerly unwanted deprotonation is the likely initiation pathway

73 attention to bioethical implications such as unwanted detection of carriers and inconclusive diagnose

74 ude that a selection process exists by which unwanted differentiating cells are eliminated from the e

75 using of light as well as holography without unwanted diffraction artefacts.

76 The fear of unwanted disclosure to insurers and the possibility of g

77 I investigated whether the reduction of the unwanted disturbance could be established through a sacc

78 ntal disorders in which patients suffer from unwanted (e.g., traumatic) memories.

79 blishing a flexible approach for suppressing unwanted editing of both off-targets and HDR-corrected s

80 9 variants, which often do not eliminate all unwanted editing.

81 the renal proximal tubule could enhance this unwanted effect.

82 their atomic thickness, which eliminates any unwanted effects associated with uneven pore profiles ob

83 To address and counterbalance unwanted effects of elastase-related proteases, chemical

84 e nuclease cleavage site, while avoiding the unwanted effects of global NHEJ inhibition.

85 l utility of an anti-IL-8 therapy to prevent unwanted effects of IL-8 up-regulation on survival, angi

86 ity; however, these drugs are complicated by unwanted effects on motor, central nervous system and ca

87 Rebound firing, which can have unwanted effects on neural circuits following inactivati

88 It also discusses strategies for preventing unwanted effects, critical to appraise the benefit or ri

89 ns, as each protein domain may contribute to unwanted effects, such as degradation, tumorigenesis, an

90 to intervene in this system without inducing unwanted effects.

91 introduce stoichiometry artifacts and other unwanted effects.

92 r, a constantly active Cas enzyme may induce unwanted effects.

93 ared to conductive probes and greatly limits unwanted electrical pickup between probe and recording s

94 hase shift without electrostatic charging or unwanted electron scattering.

95 The ability to suppress unwanted emotional memories is crucial for human mental

96 m on the singlet energy surface, creating an unwanted energy relaxation pathway.

97 irenz enhance CYP46A1 activity, with reduced unwanted enzyme inhibition at higher concentrations.

98 tidimensional NMR measurements that minimize unwanted errors.

99 Unwanted evaporation of bioassay liquids was circumvente

100 ntaining two methods to clean FCM files from unwanted events: (i) an automatic method that adopts alg

101 Unwanted evolution can underlie the emergence of drug an

102 essive role in transcription and counteracts unwanted expression in noninductive conditions.

103 us to logically block differentiation toward unwanted fates and rapidly steer pluripotent stem cells

104 Erucic acid is an unwanted fatty acid in oil.

105 ntrolling the excitation laser pulse energy, unwanted formation of rotationally excited molecular ion

106 ecular confinement that minimize the risk of unwanted genome editing.

107 ed to achieve mono-orientation, resulting in unwanted grain boundaries when the layers merge into fil

108 Unwanted greening can be inhibited by simply changing th

109 Unwanted growth of fouling organisms on underwater surfa

110 are different, thus allowing the removal of unwanted harmonic peaks.

111 ed for a broadly applicable method to remove unwanted high-abundance species prior to sequencing.

112 s) or parenteral nutrition; avoidance of any unwanted hypocarbia (PaCO(2) <30 mm Hg) without brain he

113 chronic, life-limiting illnesses to avoid an unwanted ICU admission.

114 converted to imides to prevent formation of unwanted imidate byproducts.

115 le misfolding can impact safety by eliciting unwanted immune or other off-target responses.

116 rong cytotoxic drug completely shut off this unwanted immune response.

117 n, development of diagnostics and removal of unwanted immune responses against protein therapeutics.

118 te that innate immune blockade can eliminate unwanted immune responses in gene therapy.

119 y represent an unexplored opportunity to end unwanted immune responses or to promote immune memory.

120 ry T cells (Tregs) are essential to suppress unwanted immunity or inflammation.

121 Structural changes in the mAb can lead to unwanted immunogenicity, reduced efficacy, and loss of m

122 zymatic stability, rapid body clearance, and unwanted immunostimulation.

123 s and the column matrix, which are typically unwanted in SEC applications, are utilized to separate m

124 during animal domestication has resulted in unwanted incorporation of deleterious mutations.

125 cation systems were used to avoid generating unwanted infectious interviral recombinants.

126 lled peptide chains allows one to filter out unwanted information and observe the labelled moieties o

127 y involve more rather than less attention to unwanted information.

128 ssociated with increased engagement with the unwanted information.

129 cal role in curating memories and discarding unwanted information.

130 coherence caused by the cavity decay and the unwanted inter-cavity crosstalk are greatly suppressed.

131 ce such as insulating a gene circuit against unwanted interactions with its context, and we describe

132 apping agent to compete effectively with the unwanted intermolecular reactions without interfering wi

133 ss of autophagy, through which cells capture unwanted intracellular material for lysosomal degradatio

134 the mechanisms used by host cells to remove unwanted intracellular organisms, and often found to be

135 stem (UPS) plays a critical role in removing unwanted intracellular proteins and is involved in prote

136 the entrance and/or exit mirrors can release unwanted ions while continuing to store ions of interest

137 om brine; (2) intermediate washing to remove unwanted ions; (3) final washing for unloading the lithi

138 riving SC identity are decommissioned, while unwanted lineages are de-repressed ectopically.

139 d locomotion and indirect pathway to inhibit unwanted locomotion.

140 Nulling of the unwanted long T2 signals can be achieved with an inversi

141 Momentum separators can reduce unwanted low-density gases and introduce the analyte int

142 nic molecule in solution is measured free of unwanted lower-order contamination.

143 tegically employed to balance desired versus unwanted lymphocyte inhibition.

144 llular organelle lysosome is the place where unwanted macromolecules are removed through degradation

145 rug hypersensitivity reactions are a serious unwanted manifestation of drug exposure that develops in

146 TDA promotes algal health by killing unwanted marine pathogens; however, its mode of action (

147 This negative coupling was greater when unwanted memories intruded into awareness and needed to

148 s disorder (PTSD), that are characterized by unwanted memories of distressing events.SIGNIFICANCE STA

149 ion of new information by removing unused or unwanted memories or by suppressing their expression.

150 ppression of both rehearsal and retrieval of unwanted memories, processes mediated by the prefrontal

151 ions that involve the automatic intrusion of unwanted memories.

152 le suppress retrieval given a reminder of an unwanted memory, they are considerably more likely to fo

153 e substitution about the ether bond prevents unwanted metabolic processes that can lead to rapid degr

154 However, this workflow may produce unwanted mispaired IgG species in addition to the desire

155 set of effective motor solutions to overcome unwanted motor noises related to the COM.

156 ly characterized by an inability to suppress unwanted movements, a deficit attributable to impaired s

157 omponents can help ascertain the presence of unwanted multiple scattering, which can lead to false co

158 to modulate them is essential in preventing unwanted mutation accumulation during their in vitro cul

159 to re-edit previously modified loci, causing unwanted mutations (indels) alongside intended changes.

160 imit their utility in clinical therapies, as unwanted mutations caused by DSBs can have deleterious e

161 signals and protect the quantum systems from unwanted noise originated by the output chain.

162 as traditionally been considered a source of unwanted noise, recent work demonstrates that variabilit

163 normalizing heterogeneous data can introduce unwanted noise.

164 lysis in all those studies, since it removes unwanted, non-biological variability from data.

165 We show this nanostructure strongly absorbs unwanted off-axis light rays, whilst transmitting the de

166 using ATP-competitive inhibitors may lead to unwanted off-target effects.

167 idely used for genome editing but can induce unwanted off-target mutations.

168 macodynamics properties coupled with limited unwanted off-target reactivity.

169 ally placed mismatches can be used to reduce unwanted off-target splicing events.

170 The removal of unwanted or damaged mitochondria by autophagy, a process

171 enetrations into the sampled environment are unwanted or infeasible because of health, safety, or env

172 ion of high-intensity interventions that are unwanted or non-beneficial.

173 inoculate progeny against the expression of unwanted or parasitic genetic elements.

174 ion can cause adverse drug reactions (ADRs), unwanted or unexpected events, which are a major safety

175 abolic cellular self-eating process by which unwanted organelles or proteins are delivered to lysosom

176 ity of Zika and dengue viruses, an analogous unwanted outcome might occur with some Zika virus vaccin

177 agency, avoid a sense of responsibility for unwanted outcomes, and express compassion.

178 ive luminescence mechanism, by utilizing the unwanted oxygen quenching effect of Iridium-III (Ir-III)

179 Chemotoxicity due to unwanted p53 activation in the bone marrow remains an un

180 d activation correlated with the presence of unwanted paraesthesias.

181 Application of the composite prevents unwanted partition of POT to the membrane phase, thus el

182 d hydroxide ions, as well as the blockage of unwanted pathways by adding methanol.

183 However, their unwanted persistence elsewhere or in particular situatio

184 ng that the vacuole may be key to removal of unwanted plant cells, and may carry out functions that a

185 Such materials can therefore remediate unwanted pollutants from the environment including: immo

186 ined long-term physical health in women with unwanted pregnancies after abortion versus childbirth.

187 Unwanted pregnancies remain a burden for women living wi

188 This review focuses on the unwanted production of oxygen gas, which decreases the c

189 Superparamagnetism is an unwanted property of small magnetic particles where the

190 clearing damaged organelles, pathogens, and unwanted protein aggregates.

191 strategy used in protein evolution to limit unwanted protein aggregation.

192 t complexes that catalyze the degradation of unwanted proteins and also control half-lives of key cel

193 ophagy pathway is involved in the removal of unwanted proteins and organelles through lysosomes.

194 esis beyond its established role in removing unwanted proteins from the immature vesicle.

195 lex can provide an acute response to degrade unwanted proteins under stress conditions, thereby maint

196 dic cluster serves a protective role against unwanted proteolysis by endogenous proteases.

197 rotected 2-KPCC's reactive intermediate from unwanted protonation; however, without its input as a ca

198 : Instead of deterministically reversing the unwanted qubit evolution, we use control pulses to shape

199 ntrolling SAM dual reactivity and preventing unwanted radical-based chemistry before the K2 [Fe(4)S(4

200 kynes with surface metal atoms often induces unwanted reaction pathways when thermal energy is provid

201 to function as activation barrier to prevent unwanted reactions against minor allergens.

202 free PLP concentrations low enough to avoid unwanted reactions with other important cellular nucleop

203 n of the olefin produced, leading to further unwanted reactions.

204 A Pt-catalyzed hydrosilylation helped stymie unwanted rearrangements facilitated by vinyl group parti

205 GD for mercury capture is the possibility of unwanted reduction of dissolved Hg(2+), leading to the r

206 However, this led to the production of unwanted reductive aroma compounds in some wines.

207 ators may be useful in management to prevent unwanted regime shifts, at least in some situations.

208 t and environmental conditions, to avoid the unwanted release of plastic degradation products in rece

209 ontrol sex-ratio in GIFT tilapia to suppress unwanted reproduction during growout.

210 he 11-cis configuration and protects against unwanted retinaldehyde activity.

211 A bases(5), and created selective curbing of unwanted RNA editing (SECURE)-BE3 variants that have red

212 ting (SECURE)-BE3 variants that have reduced unwanted RNA-editing activity(5).

213 ts, which has the advantage of removing many unwanted rRNA and tRNA reads.

214 Unwanted sample heating and nuclear Overhauser effect (N

215 h few useful applications, the production of unwanted SCT leads to the need for its costly disposal o

216 rentially expressed, to predict and decrease unwanted secondary effects and increase potency.

217 thylenediaminetetraacetate (EDTA), result in unwanted sensory properties and/or gastrointestinal dysf

218 ation for Cas9 in vitro, using it to deplete unwanted sequence from DNA libraries.

219 No major unwanted short-term effects on AC structure, proteoglyca

220 after a course of antibiotics, which has the unwanted side effect of depleting commensal bacteria.

221 y deprivation, it can lead to tinnitus as an unwanted side effect.

222 Reductions in unwanted side effects (e.g., hemorrhage or immunogenicit

223 ment methods for KS and PEL are fraught with unwanted side effects and low efficiency, the search for

224 herapeutics exhibit limitations in efficacy, unwanted side effects and the potential for drug abuse a

225 in in rodents without producing tolerance or unwanted side effects associated with CB1 receptors; how

226 Moreover, the absence of unwanted side effects in our cytological studies, and th

227 fective, lack of selectivity for GR leads to unwanted side effects in some patients.

228 PPIs may have unwanted side effects in vulnerable populations.

229 ERPIN-ICU program, weighed against potential unwanted side effects is favourable.

230 lance between putative benefit and potential unwanted side effects needs to be considered.

231 lance between putative benefit and potential unwanted side effects needs to be considered.

232 AC fields for electroporation eliminates the unwanted side effects of electrolysis or joule heating a

233 d strategies of drought tolerance that avoid unwanted side effects that limit growth and yield, and m

234 t dosing intervals, peripheral vasodilation, unwanted side effects, and restricted use in pediatric p

235 get binding of hydrophobic drugs can lead to unwanted side effects, either through specific or non-sp

236 ch of today's pharmacopeia can cause serious unwanted side effects, such as immune suppression.

237 that resolve infectious inflammation without unwanted side effects.

238 cs of the drug, enhance efficacy, and reduce unwanted side effects.

239 s have also shown beneficial effect, without unwanted side effects.

240 properties, and poor selectivity along with unwanted side effects.

241 role in drug development to eliminate their unwanted side effects.

242 equences for treating disease and minimizing unwanted side effects.

243 however, systemic delivery of H2S may cause unwanted side effects.

244 al ischemia-reperfusion injury and may avoid unwanted side effects.

245 rmacological treatments without evidence for unwanted side effects.

246 ischemia-reperfusion injury and could avoid unwanted side effects.

247 h cytotoxicity, poor tissue penetration, and unwanted side effects.

248 nucleic acids must also be designed to avoid unwanted side effects; thus, the ability of such carrier

249 es to produce the desired products and avoid unwanted side products.

250 Deprotonation usually occurs as an unwanted side reaction in the Lewis pair polymerization

251 on reactions with metal cations, which avoid unwanted side reactions and positive feedback mechanisms

252 e replacement of lithium metal anode impedes unwanted side reactions between the dissolved intermedia

253 tive design strategies that explicitly avoid unwanted side reactions have been underexplored.

254 Low-temperature activation may avoid unwanted side reactions in the development of catalytic

255 many women do not want to take them owing to unwanted side-effects impacting, for example, the uterus

256 whilst rendering the technique sensitive to unwanted size fractions from unclean lab-ware, dust and

257 and demonstrates how the epidermis triggers unwanted skin inflammation under disease conditions.

258 ns associated with these approaches, such as unwanted sources of variation that influence clustering

259 After accounting for unwanted sources of variation, we identified 106 differe

260 lexed with a library of guide RNAs targeting unwanted species for cleavage, thus preventing them from

261 ty and thereby protects the pancreas against unwanted SPINK1 degradation.

262 unnecessary administration of antibiotics or unwanted spread of spores in any hospital setting, respe

263 ed on fluorescence excitation that can cause unwanted stimulation of the optogenetic probe and other

264 oisosteric replacement concepts to eliminate unwanted structural motifs and to improve the inhibitor

265 cus on surface modification to suppress this unwanted structural transformation.

266 rom a network based on their similarity with unwanted substances (e.g. failed drugs) and (ix) build c

267 alian conducting airways expel pathogens and unwanted surface materials from the respiratory tract, d

268 Such unwanted surfactants have now been utilized to stabilize

269 ing methods and can significantly reduce the unwanted systematic variation, revealing biological vari

270 ng random forest (SERRF) for eliminating the unwanted systematic variations in large sample sets.

271 ed advanced clinical trials because of their unwanted systemic side effects.

272 non-specific delivery would inevitably cause unwanted systemic side effects.

273 ral challenge is assessing if the removal of unwanted technical variation harms the biological signal

274 he realistic deposition pattern and decrease unwanted therapeutic aerosol deposition at the extrathor

275 Subjects viewed reminders of unwanted thoughts and tried to suppress retrieval while

276 ory is essential for cognition, but removing unwanted thoughts is equally important.

277 How hippocampal GABA contributes to stopping unwanted thoughts is unknown.

278 rformance state, and responsively to address unwanted thoughts or emotions to re-enter an acceptable

279 mors and minimizing side-effects by avoiding unwanted tissue heating.

280 tumors arising from undifferentiated hPSCs), unwanted tissues, and other types of adverse events.

281 gn limitations of CAR-T cells for cancer are unwanted tonic (antigen-independent) signaling and off-t

282 e in reducing off-target effects, decreasing unwanted toxicities, and thereby enhancing a drug's ther

283 bers of cycles required and, in turn, reduce unwanted toxicities.

284 tandard in treating bipolar disorder but has unwanted toxicity and side effects.

285 pecific enhanced bioavailability and limited unwanted toxicity, thus leading to a significant potenti

286 In particular, the higher tendency of unwanted transition-metal-ion dissolution and side-react

287 t twisting in target DNA and thus attenuates unwanted transposition.

288 To avoid unwanted truncated protein and improve ncAA-protein yiel

289 which confounds real biological signals with unwanted variability.

290 the method by Houseman et al., the Removing unwanted variation (RUV) approach, the methods in FaST-L

291 e negative controls and replicates to remove unwanted variation and enhance biological signal, outper

292 Biases, artifacts and other sources of unwanted variation are present in the data, requiring su

293 We discuss how to deal with sources of unwanted variation, and propose ways to further improve

294 tissue culture is known to engender frequent unwanted variation, termed somaclonal variation.

295 making use of control data in the removal of unwanted variation, we propose a variant of principal co

296 present a new normalization method, Removing Unwanted Variation-III (RUV-III), which makes vital use

297 to diverse sources of variation, including 'unwanted' variation that needs to be removed in downstre

298 Unwanted weight gain affects some people living with HIV

299 uth, via IT, they express great concern, and unwanted weight gain in young people can be prevented by

300 pes and might serve as a target for limiting unwanted xenogeneic fusion in the future.