ライフサイエンスコーパス: upper limb

1 rol over very short time scales (<100 ms for upper limb).

2 ferences between the thrust produced by each upper-limb).

3 task dependency in vestibular control of the upper limb.

4 lly identified motoneurons projecting to the upper limb.

5 wing mechanical perturbations applied to the upper limb.

6 y reflects the flexible usage of the primate upper limb.

7 ivity patterns for different segments of the upper limb.

8 rceived self-attribution and position of the upper limb.

9 n about natural, multijoint movements of the upper limb.

10 mpany gains in motor function of the paretic upper limb.

11 arterial network in TSP2-null muscles of the upper limb.

12 cribed by others in quiescent muscles of the upper limb.

13 of the left and right distal muscles of the upper limb.

14 ormally innervated face and the deafferented upper limb.

15 thout it, while simulating disability of the upper limb.

16 electrical burn requiring amputation of his upper limbs.

17 presented with mild myoclonus affecting the upper limbs.

18 hboring regions that represent the trunk and upper limbs.

19 ons can directly influence movements of both upper limbs.

20 erosseous were predominantly involved in the upper limbs.

21 ost patients and affected lower earlier than upper limbs.

22 0.05) between the dominant and non-dominant upper-limbs.

23 on by re-engaging functional activity of the upper limbs?

24 lants have been performed at 14 programs (10 upper limb, 10 uterus, 5 craniofacial, 1 scalp, 1 abdomi

25 th organs donated by 70 donors, including 30 upper limb (17 unilateral and 13 bilateral) and 11 face

26 b weakness that subsequently expanded to the upper limbs, (2) cerebellar ataxia, (3) psychosis and/or

27 re on the head and/or neck (435 [33.4%]) and upper limbs (455 [34.9%]).

28 were more obvious in the lower limb than the upper limb (59% versus 29%).

29 identify how sensorimotor adaptation of the upper limb, a cerebellar-dependent process restoring mov

30 haracterized by congenital heart defects and upper limb abnormalities.

31 of functional recovery for individuals with upper limb absence.

32 y and motor functions of the stroke-affected upper limb, accompanied by cortical plasticity.

33 ent with a compensatory response to maintain upper-limb accuracy in the face of body movement.

34 nticipate, predict, comprehend, and memorize upper limb actions, which they cannot simulate, as effic

35 outflow is the most important determinant of upper limb akinesia in Parkinson's disease.

36 lidotomy on previously described measures of upper limb akinesia in Parkinson's disease.

37 Various measures of upper limb akinesia were assessed in 6 patients with bil

38 ed in a supine position, with head extended, upper limbs aligned to the trunk, and knees flexed.

39 nd is characterized by kinetic tremor of the upper limbs, although other clinical features can also o

40 Here, we demonstrate in four people with upper-limb amputation that epidural spinal cord stimulat

41 in the design of prosthetic arms have helped upper limb amputees achieve greater levels of function.

42 ing functional MRI (fMRI) we investigated 13 upper limb amputees with phantom limb pain (PLP) during

43 reassess its relationship to phantom pain in upper limb amputees.

44 push towards restoring sensory perception to upper-limb amputees, which includes the whole spectrum f

45 with real-time control experiments involving upper-limb amputees.

46 tional Rating Scale-Revised (ALSFRS-R total, upper limb and bulbar) and upper motor neuron burden ass

47 ed collateral growth (arteriogenesis) in the upper limb and capillary formation and vessel maturation

48 ls originating near the ligation site in the upper limb and connecting to the ischemic calf muscle re

49 s was 24.9 and varied widely, especially for upper limb and face donors.

50 workers handling a mine, resulting in severe upper limb and facial injuries.

51 improvement in functional use of the paretic upper limb and quality of life 2 years after a 2-week CI

52 king system to track markers placed on their upper limb and recorded single-unit activity from a micr

53 or as well a cognitive performance, posture, upper limb and working memory function were assessed in

54 with sensory ataxia, severe weakness of the upper limbs and axial muscles with distinctly preserved

55 Other donors donated both upper limbs and face (n = 2), uterus (n = 4), abdominal

56 significant neurological amelioration in the upper limbs and trunk with more-modest amelioration in t

57 rt symptoms experienced in every part of the upper limbs and vertebral spine.

58 urophysiologically active involvement of the upper limbs and were compared with MR images in 12 age-m

59 n between shape elements, which characterize upper limbs, and upper-limb-specific motion patterns.

60 ngruent visuoproprioceptive signals from the upper limb are essential for successful VT integration.

61 tures, as non-object directed actions of the upper limb are not well characterized in non-human prima

62 han control group in bilateral head-face and upper-limb areas (p < 0.05).

63 d cervical-onset may date from head-face and upper-limb areas in motor homunculus cortex, respectivel

64 In upper-limb areas, the cortical thickness of cervical-ons

65 ible for the swim speed achieved during each upper-limb arm-pull.

66 in the speed achieved while performing each upper-limb arm-pull.

67 s in the speed achieved by each one of their upper-limbs arm-pull.

68 , we selected all patients in whom bilateral upper limb arterial anatomy was assessed based on the pe

69 An ABC upper limb arterial axis variant was detected in 156 (25

70 Upper limb ataxia was evident in 75%, lower limb ataxia

71 d with duplex US for vascular mapping before upper limb AVF creation in participants with CKD.

72 th a subsequent good or poor recovery of the upper limb based solely on a T1-weighted structural brai

73 r cortex (PMv) represent the position of the upper limbs based on visual and proprioceptive informati

74 minimum level of grip is required before the upper limb becomes active in balance control and also th

75 The types of cut marks on upper limb bones indicate simple flesh removal activitie

76 hals were more heavily muscled, had stronger upper-limb bones, and possessed unusual shapes and orien

77 ction velocity was moderately reduced in the upper limbs but unobtainable in the legs.

78 e interventions, including evaluation of the upper limbs by Fugl-Meyer Assessment (FMA; primary outco

79 , it remains unknown whether training of the upper limb can induce the cross-transfer effect to the t

80 uce bidirectional changes in excitability in upper limb CM pathways.

81 A significant group x time interaction in upper limb (combined hand and modified arm) Fugl-Meyer a

82 with the long-standing cortical network for upper limb control.

83 4.0; 95% confidence interval 1.6-10) but not upper-limb deep venous thrombosis (odds ratio 0.6; 95% c

84 autosomal dominant disorder characterized by upper limb defects, apocrine-gland defects including mam

85 In patients with long-term upper-limb deficits after stroke, robot-assisted therapy

86 haracterized by congenital heart defects and upper limb deformations.

87 mers exhibit significant differences between upper-limbs determinants.

88 dy aimed to: (1) verify a hypothetical inter-upper limb difference in the determinants related to fro

89 no demonstrable effects on the occurrence of upper limb digital ulcers or on other vascular manifesta

90 asures and clinical measures (pain severity, upper limb disability, disease duration).

91 subcortical stroke patients with unilateral upper limb disability.

92 e differ in people with more severe baseline upper-limb disability and cerebrovascular disease.

93 of losing clinically meaningful mobility and upper limb disease progression milestones across the lif

94 movements is to maintain the accuracy of the upper limb during unpredictable body movement, but only

95 ed by their involvement in the processing of upper-limb dynamics.

96 th absent or severely shortened upper limbs (upper limb dysplasia), despite some variability, could p

97 viduals born without hands (individuals with upper limb dysplasia), who use tools with their feet.

98 Upper limb EMGs were recorded to control for covert musc

99 difference between dominant and non-dominant upper-limbs (except for the hand surface area).

100 -like) and derived (Homo-like) features, the upper limbs (excluding the hand and wrist) of the Malapa

101 lude that the motor networks controlling the upper limb exhibit an intrinsic periodicity at submoveme

102 inal projections to the motor neuron pool of upper-limb extensor muscles have been reported to differ

103 t of lamina IX, noted for harboring proximal upper limb flexor motoneurons.

104 puzzling observation is that, after stroke, upper limb flexor muscles show good recovery but extenso

105 itate responsiveness of the motor pathway to upper limb flexor muscles.

106 eas and the transformation of the use of the upper limbs from a purely locomotor function to one incl

107 and 6 months after treatment, with modified upper limb Fugl-Meyer (FM-UL, max-54), Action Research A

108 t-assisted training and EULT did not improve upper limb function after stroke compared with usual car

109 vical cord area was associated with impaired upper limb function and increased activations with handg

110 Improvements in upper limb function occurred at 3, 6 and 12 months, but

111 icantly declined in patients who worsened in upper limb function over the follow-up period (n=9, p=0.

112 al research, few are available for measuring upper limb function post-stroke.

113 CST-wiring-dependent, although the impact on upper limb function remains unclear.

114 The primary outcome was upper limb function success (defined using the Action Re

115 Upper limb function was generally less impaired, but 54%

116 for the primary outcome measure of impaired upper limb function, as measured with the Wolf motor fun

117 point to a more consistent effect on distal upper limb function, especially for inhibitory (cathodal

118 e cervical CST also correlated with impaired upper limb function, independent of cord area (p = 0.03)

119 in clinically significant gains in tests of upper limb function.

120 limb was assessed with clinical measures of upper limb function.

121 te axonal changes within the cranial CST and upper limb function.

122 nderstanding of healthy and sensory-impaired upper limb function.

123 EULT (aOR 1.51 [0.90-2.51]) did not improve upper limb function; the effects of robot-assisted train

124 ence for low-level, hardwired constraints on upper-limb function.

125 ed at least 18 years with moderate or severe upper limb functional limitation, between 1 week and 5 y

126 al care for patients with moderate or severe upper limb functional limitation.

127 er-limb training program designed to improve upper-limb functional motor capacity.

128 cognitive retardation; abnormalities of the upper limbs; gastroesophageal dysfunction; cardiac, opht

129 We assessed neurological recovery weekly by upper-limb grip strength.

130 l malformations, in particular craniofacial, upper limb, heart, and urinary system defects that are p

131 level regression, the speed achieved by each upper-limb identified a set of variables, with the peak

132 ent study we show that selectivity to static upper-limb images and motion processing go hand in hand.

133 We propose that the selectivity to static upper-limb images in the OTC may be a result of experien

134 Upper limb impairment and activity were assessed on admi

135 chronic stroke who had presented with severe upper limb impairment and asked whether it was possible

136 hypothesized that proportional resolution of upper limb impairment depends on ipsilesional corticomot

137 For most patients, resolution of upper limb impairment during the first 6 months poststro

138 By 12 weeks, upper limb impairment resolved by 70% in patients with M

139 These findings indicate that upper limb impairment resolves by 70% of the maximum pos

140 Upper limb impairment was measured in 93 patients at 2,

141 In one form of CIMT to treat upper limb impairment, use of the less severely affected

142 volving 127 patients with moderate-to-severe upper-limb impairment 6 months or more after a stroke, w

143 ent therapy (CIMT) was developed to overcome upper limb impairments after stroke and is the most inve

144 Those with upper limb impairments completed the DASH again at 6 wee

145 n 17 patients, lower limb in 31 patients and upper limb in 28 patients.

146 After long-term denervation of an upper limb in macaque monkeys, the representation of the

147 n provided via TMSR affected the maps of the upper limb in primary motor (M1) and primary somatosenso

148 it into a multisensory representation of the upper limb in space.

149 f peri-hand neurons in the perception of the upper limbs in any species.

150 ces dynamically represent the space near the upper limbs in hand-centered coordinates.

151 ty to static images of human body parts, and upper limbs in particular, with respect to other object

152 rs characterized by progressive gait ataxia, upper limb incoordination, and dysarthria.

153 neuroimaging study with people born without upper limbs-individuals with dysplasia-who use the feet

154 The evolution of the human upper limb involved a change in function from its use fo

155 h of the muscles within the total sum of the upper limbs involved in the study.

156 ss began between the ages of 8 and 16 years, upper limb involvement beginning between 10 and 43 years

157 predominant cervical, bulbar, orofacial, and upper limb involvement.

158 een proposed that functional selectivity for upper limbs is driven by processing of their distinctive

159 ing consisted of three 5-min cycles of right upper limb ischaemia, induced by an automated cuff-infla

160 e ischaemic preconditioning, using transient upper limb ischaemia.

161 e human forearm was induced by 20 minutes of upper limb ischemia (inflation of a blood pressure cuff

162 adial access despite several risk factors of upper limb ischemia - diabetes, end-stage renal failure,

163 One of them is upper limb ischemia caused by radial artery thrombosis.

164 IR injury was induced by 20 minutes of upper limb ischemia followed by reperfusion.

165 te ischemic preconditioning, using cycles of upper limb ischemia-reperfusion as a conditioning stimul

166 yperparathyroidism, or even symptoms of left upper limb ischemia.

167 ssed unusual shapes and orientations of some upper-limb joint complexes relative to the Skhul/Qafzeh

168 ributed neural representation of ipsilateral upper limb kinematics in both monkey and man.

169 a fine rhythmic oscillation involving distal upper limbs, linked to increased sensorimotor cortex exc

170 ential in restoring function for people with upper-limb loss.

171 Compared to the upper limb, lower limb distal nerve transfer (DNT) outco

172 ral nervous system region defined as bulbar, upper limb, lower limb or diaphragmatic), diagnosis, fun

173 s demonstrate that vestibular control of the upper limb maintains reaching accuracy during unpredicta

174 heart-hand" disorders, with a combination of upper limb malformations and cardiac defects.

175 abnormalities; others might cause extensive upper limb malformations but less significant cardiac ab

176 and Arg237Gln and Arg237Trp caused extensive upper limb malformations but less significant cardiac ab

177 disorder characterized by facial dysmorphia, upper limb malformations, growth and cognitive retardati

178 tional connectivity in TMSR patients between upper limb maps in M1 and S1 was comparable with healthy

179 e head & neck (35 days) was shorter than the upper limb (mean = 64 days, p = 0.02) and lower limb (me

180 cate areas for improvement of the DASH as an upper limb measure for acute stroke.

181 associated with faster disease progression (upper-limb Medical Research Council scale progression ra

182 of mobility milestones by 2.1-4.4 years and upper limb milestones by 2.8-8.0 years compared with tre

183 lated and clinically meaningful mobility and upper limb milestones.

184 surements of recurrent inhibition in primate upper limb motoneurons, revealing that it is more flexib

185 information from the corticospinal tract to upper limb motoneurons.

186 oad but most patients with E90K and N98S had upper limb motor conduction velocities <38 m/s.

187 rwent ultra-high field (1)H-MRS scans of the upper limb motor cortex and pons, ALS Functional Rating

188 contribution weight of lesion likelihood to upper limb motor deficit.

189 dy in adults aged >40 years with significant upper limb motor deficits 2-13 months after ischaemic st

190 Upper limb motor deficits in severe stroke survivors oft

191 Additionally, relations with upper limb motor deficits were explored.

192 INTERPRETATION: Our results suggest that upper limb motor execution, and particularly dexterous c

193 Upper limb motor function scores, electromyography from

194 l in elderly humans experiencing declines in upper limb motor functions.

195 ential of dopaminergic treatments to improve upper limb motor movements was tested in 7 aged rhesus m

196 L-Dopa or GBR-12909 improved upper limb motor performance by up to 40% in the aged an

197 tomical structures in supporting post-stroke upper limb motor recovery and points towards methodologi

198 mal use of these new technologies to enhance upper limb motor recovery especially in severe chronic s

199 udies-one of the largest overall datasets of upper limb motor recovery.

200 rmance correlated with MEP amplitudes in the upper limb motor region.

201 combined technology-aided interventions for upper limb motor rehabilitation after stroke, including

202 have the potential to significantly support upper limb motor restoration in severely impaired stroke

203 r imagery in stroke patients with persistent upper limb motor weakness.

204 In addition, upper-limb motor performance times of the aged GDNF-trea

205 1 may promote proximal, and possibly distal, upper-limb motor recovery following frontal and frontopa

206 and 12 months, but not in those with absent upper limb movement at baseline, suggesting a possible t

207 in ARAT was seen only in those with residual upper limb movement at baseline.

208 correlate with poorer levels of recovery of upper limb movement.

209 s involved in 4 weeks of mental rehearsal of upper limb movements during 45-min supervised sessions t

210 s structured to influence axial and proximal upper limb movements, supporting Kuypers conceptual view

211 lliculus (SC) are involved in the control of upper limb movements.

212 Upper-limb movements are often composed of regular submo

213 score (a composite measure of walking speed, upper-limb movements, and cognition; for this z score, n

214 Here, we recorded SLRs from an upper limb muscle while humans reached toward (pro-reach

215 fects of abobotulinumtoxinA injection in the upper limb muscles on muscle tone, spasticity, active mo

216 nA at doses of 500 U or 1000 U injected into upper limb muscles provided tone reduction and clinical

217 st that the corticospinal drive to lower and upper limb muscles shows significant developmental chang

218 On each day, motor-evoked potentials in upper limb muscles were first measured after stimulation

219 These PTNs facilitate EMG activity in upper limb muscles, contributing to corticomuscular cohe

220 pinal input to the spinal segments supplying upper limb muscles, whilst leaving intact excitation tra

221 sponsiveness of corticospinal projections to upper limb muscles.

222 logically exaggerated common drive in distal upper limb muscles.

223 tant disparities between proximal and distal upper limb muscles.

224 e recorded myoelectric signals from multiple upper-limb muscles in subjects with cortical lesions.

225 Distal upper limb myopathy/cachexia is not previously described

226 unrelated patients in whom a distal, mainly upper limb, myopathy was the predominant and early clini

227 ncompassed small and large insertions in the upper limb (n = 21), lower limb (n = 27), and spine (n =

228 severity scale scores, greater reduction of upper limb nerve conduction study amplitudes, more frequ

229 e analysis of the axonal components of human upper limb nerves based on highly specific molecular fea

230 bly increase the dexterity and embodiment of upper-limb neuroprostheses and will constitute an import

231 To restore motor function with upper-limb neuroprostheses requires that somatosensory f

232 We propose that this approach could equip upper-limb neuroprostheses with direct access to texture

233 vers high-quality, high-dose, high-intensity upper limb neurorehabilitation during a 3-week (90 hours

234 The Queen Square Upper Limb Neurorehabilitation programme delivers high-q

235 The upper-limb noting a higher dry-land strength also presen

236 r synergist and non-synergist muscles of the upper limb occur in the newborn baby and become restrict

237 s in promoting motor function of the paretic upper limb of stroke patients.

238 re post-depositional, but those in the right upper limb of the adult hominin strongly indicate active

239 from the spinal cord to innervate the human upper limb, of which 10% are motor neurons.

240 racterized by predominant myoclonic jerks of upper limbs, often provoked by cognitive activities, and

241 There were 659 people with upper limb onset of weakness.

242 Subgroups with bulbar, lower and upper limb onset showed different decline rates of ALSFR

243 and triceps in patients with a diagnosis of upper limb-onset ALS in the 19-year period 1996-2015.

244 patient subgroups classified by the rate of upper limb or bulbar functional decline.

245 lism, symptomatic deep-vein thrombosis in an upper limb or distal deep-vein thrombosis in a lower lim

246 tation (TFD) of parts of the stroke-affected upper limb or of the less-affected contralateral limb mi

247 jects received RIPC (or placebo) stimuli (x3 upper limb (or dummy arm), 5-minute cycles of 200 mm Hg

248 (p < 0.05) between dominant and non-dominant upper-limbs over a 25 m time-trial in a short-course poo

249 developed to restore function to people with upper-limb paralysis.

250 tional capacity in people with long-standing upper-limb paresis poststroke.

251 The upper limb perimeter decreased in 7 of 9 patients.

252 inimum level of grip is necessary before the upper limb plays an active role in vestibular-evoked bal

253 Significant improvements in contralateral upper limb postural (P2) and kinetic tremors, spiral sco

254 ered in the differential diagnosis of distal upper limb predominant myopathy.

255 ions, known to be important for multisensory upper limb processing.

256 However, control of upper limb prostheses is limited by the lack of sensory

257 esigning a real-time pain reaction system in upper-limb prostheses.

258 abilitation (CMR) is a promising therapy for upper limb recovery in stroke, but the brain mechanisms

259 ults will contribute to the understanding of upper limb recovery patterns in the first 6 months after

260 t results confirm that neurotechnology-aided upper limb rehabilitation is promising for severe chroni

261 With intensive upper limb rehabilitation, chronic stroke patients can c

262 of vagus nerve stimulation (VNS) paired with upper-limb rehabilitation after ischemic stroke.

263 s to conclude that significant between-group upper-limb-related behavioral differences must have been

264 Persistent difficulty in using the upper limb remains a major contributor to physical disab

265 istal and proximal motor compensation of the upper limb, respectively.

266 vanic vestibular stimulation (GVS) can evoke upper limb responses to maintain balance.

267 Upper-limb RIPC performed while patients were under prop

268 The trial compared upper-limb RIPC with a sham intervention.

269 ty in multivoxel activation patterns in both upper-limb-selective OTC regions and the hMT+.

270 s suggest that the functional specificity of upper-limb-selective regions may be partially determined

271 hV4 or LO-1, suggesting a tight link between upper-limb selectivity and motion processing.

272 Sympathetic denervation of the upper limb significantly improves forearm skeletal muscl

273 tematically perceived the position of moving upper limbs slightly ahead of their real position but on

274 On the hairy skin of the upper limb, spatial acuity for pain and touch followed o

275 anscranial magnetic stimulation in the right upper limb (Spearman rho = -0.57; 95% confidence interva

276 lements, which characterize upper limbs, and upper-limb-specific motion patterns.

277 Upper limb strength is only mildly affected and cardiac

278 gs in motor cortex as rats learned a skilled upper-limb task.

279 naturalistic movements involving the entire upper limb, the results also suggest that achieving high

280 ical anatomy of nerves innervating the human upper limbs, the definite quantity of sensory and motor

281 In relation to the upper limbs, the main predictor of outcome is initial se

282 g the MIT-Manus robotic gym with an enhanced upper limb therapy (EULT) programme based on repetitive

283 Resolution of impairment was insensitive to upper limb therapy dose.

284 bility in this pathway, and is unaffected by upper limb therapy dose.

285 nce swimmers may exhibit imbalances in their upper-limbs' thrust (differences between the thrust prod

286 n individualized, progressive, task-specific upper-limb training program designed to improve upper-li

287 A 3 Hz 'filter' for postural (P2) upper limb tremor was detected by accelerometry/spectral

288 hronization and independence with respect to upper limb tremor.

289 head tremor and the majority had additional upper-limb tremor.

290 duals born with absent or severely shortened upper limbs (upper limb dysplasia), despite some variabi

291 cle spindle afferents are also absent in the upper limb, we assessed whether proprioception at the el

292 of consciousness, effort-associated vertigo, upper limb weakness and temporary vision problems.

293 included 121 stroke patients with a residual upper limb weakness within 6 months following stroke (on

294 t subject (aged 57 years), and marked distal upper limb weakness.

295 All participants had moderate to severe upper-limb weakness and were randomised to 6-weeks inten

296 At an individual level, those patients whose upper limbs were most affected had a higher incidence of

297 Upper limbs were procured from brain-dead organ donors.

298 of these tremors, the action tremors of the upper limbs were subclassified according to the predomin

299 ion is sparse for the control of the primate upper limb, where no direct measurements have been made

300 activates selective groups of muscles in the upper limbs with unmet precision.