1 Strategies to increase capacity are needed
urgently.
2 Safe and effective vaccines are needed
urgently.
3 Effective treatments are needed
urgently.
4 hods targeting antigens need to be developed
urgently.
5 Animal models are
urgently being developed for SARS-CoV-2 to aid rational
6 Dealing with the current pandemic
urgently demands serious reform and collective efforts.
7 nd hypoxia active are scarcely available and
urgently desired for antitumor photodynamic therapy (PDT
8 on, highly robust and durable electrodes are
urgently desired to facilitate water oxidation and oxyge
9 on the readout side of AFM-based devices are
urgently desired.
10 It is imperative that policy makers
urgently ensure the integration of such risk factors on
11 izing disorders such as alcohol misuse calls
urgently for effective prevention and intervention.
12 t recapitulate SARS-CoV-2 disease are needed
urgently for rapid evaluation of medical countermeasures
13 , fisheries, oil-gas extraction, and mining)
urgently imposes the development of novel monitoring tec
14 hotography findings and urgency of referral (
urgently in <= 2 weeks vs. nonurgently in > 2 weeks).
15 ry and distanced-based approaches, should be
urgently included in a framework of ecosystem-based mana
16 r-specific and differentiating factors to be
urgently included in the research, prevention, and thera
17 cluded were inpatients at 4 centers who were
urgently listed as nonstatus 1 and transplanted from 200
18 population and a limited therapeutic toolbox
urgently necessitate new approaches to treat neurodegene
19 sease is a major cause of renal failure that
urgently necessitates a breakthrough in disease manageme
20 difficult-to-target pathogens, for which we
urgently need a better understanding of protective immun
21 ancers, particularly high-risk solid tumors,
urgently need effective and specific therapies.
22 In addition to these measures, we
urgently need effective interventions to increase adhere
23 ng the battle against online hate(19,20) and
urgently need new insights.
24 Thus, decision makers
urgently need scientific evidence on GBH residues and th
25 Antibiotic resistance is rising and we
urgently need to gain a better quantitative understandin
26 ntion of functionally diverse ecosystems, we
urgently need to implement mechanisms for increasing far
27 especially in the most intact areas, are now
urgently needed alongside current efforts aimed at halti
28 he cancer-control continuum in the region is
urgently needed and can be accomplished through collabor
29 Interventions are
urgently needed and should target ART clinic, hospital,
30 icrobiota-autoimmunity interplay in AIDs are
urgently needed and underway to explore novel and precis
31 omising target for the development of novel,
urgently needed anti-staphylococcal agents.
32 trategies for mosquito control, which may be
urgently needed as the geographical ranges of vector spe
33 hronic hepatitis B virus (HBV) infection are
urgently needed because of viral integration, persistenc
34 al mechanisms in Parkinson's disease (PD) is
urgently needed because the number of affected individua
35 rategies to prevent and treat infections are
urgently needed because the rapid rise in drug-resistant
36 at builds on this foundation will enable the
urgently needed comprehensive spatiotemporal understandi
37 ic level and included in a comprehensive and
urgently needed conservation plan.
38 against respiratory syncytial virus (RSV) is
urgently needed due to the public health significance of
39 ethods for fatty acid (FA) determination are
urgently needed due to their critical biochemical roles
40 Evidence-based guidelines are
urgently needed for all health-care settings, from terti
41 Novel approaches for adjunctive therapy are
urgently needed for complicated infections and patients
42 easure SARS-CoV-2 neutralizing antibodies is
urgently needed for COVID-19 serodiagnosis, convalescent
43 markers for organismal decline and aging are
urgently needed for diagnostic and drug development.
44 Novel therapies are
urgently needed for ovarian cancer, the deadliest gyneco
45 ut peptide synthesis technology is therefore
urgently needed for patient-specific cancer vaccines to
46 t preserve the redox state of the tissue are
urgently needed for refined studies of the underlying me
47 ods to monitor their evolutionary trends are
urgently needed for the development of antivirals and va
48 ealth Organization, and new technologies are
urgently needed for the early diagnosis and monitoring o
49 Effective therapies are
urgently needed for the SARS-CoV-2/COVID-19 pandemic.
50 Efficacious interventions are
urgently needed for the treatment of COVID-19.
51 Biological time series data are thus
urgently needed for the world's oceans.
52 n of electrochemical microfluidic devices is
urgently needed for transferring such devices from funda
53 Age-stratified estimates of RSV burden are
urgently needed for vaccine implementation.
54 are of clinical relevance for the design of
urgently needed HCV B-cell vaccines and might help to in
55 on to parvalbumins, should be considered for
urgently needed improved fish allergy diagnostics.
56 and protocols for patient stratification are
urgently needed in cancer nanomedicine, to identify indi
57 rder to develop the nutrient-efficient crops
urgently needed in global agriculture.
58 nd inactive bacteria at single cell level is
urgently needed in many fields including clinical diagno
59 ting the safety and efficacy of apixaban are
urgently needed in patients with advanced chronic kidney
60 A novel intervention is
urgently needed in the absence of specific, targeted the
61 of supplies and health worker behaviours are
urgently needed in the face of the current pandemic.
62 of new SARS-CoV-2 transmission clusters are
urgently needed in the United States and other countries
63 s will be important in evaluation and use of
urgently needed interventions.
64 w needed to translate these discoveries into
urgently needed therapies.
65 tools to establish the cause of viremia are
urgently needed to accelerate clinical decision-making.
66 More randomized trials are
urgently needed to address important clinical questions
67 New antifungal drugs are
urgently needed to address the emergence and transcontin
68 Novel antibiotics are
urgently needed to address the looming global crisis of
69 cs for the treatment of neuropathic pain are
urgently needed to address the ongoing opioid crisis.
70 pective trials that are widely available are
urgently needed to advance the field.
71 Improved understanding is
urgently needed to allow development of targeted interve
72 ng genome data, machine learning methods are
urgently needed to analyze large sets of gene trees over
73 gned and powered epidemiological studies are
urgently needed to assess the association between sustai
74 imal treatment of isoniazid-resistant TB are
urgently needed to avert the de novo emergence of MDR-TB
75 preconception period and early pregnancy are
urgently needed to better protect pregnant women and the
76 Additional research endeavors are
urgently needed to better understand and identify risk f
77 erventions specific to HIV-endemic areas are
urgently needed to block tuberculosis transmission.
78 cterization and integrated data modeling are
urgently needed to characterize the microbial constituen
79 Novel antimicrobials are
urgently needed to combat drug-resistant bacteria and to
80 lecular targets and treatment strategies are
urgently needed to combat it.
81 Novel antibiotics are
urgently needed to combat multidrug-resistant pathogens.
82 Cost-effective, efficacious therapeutics are
urgently needed to combat the COVID-19 pandemic.
83 eutic approach that minimizes these risks is
urgently needed to combat this deadly disease and preven
84 Thus, prospective studies are
urgently needed to confirm the underlying biology, predi
85 ines are an essential countermeasure and are
urgently needed to control the pandemic(4).
86 Intervention strategies are
urgently needed to control the severe acute respiratory
87 for coronavirus disease 2019 (COVID-19) are
urgently needed to control this current pandemic, caused
88 uitable platforms and conjugation routes are
urgently needed to convert the promise of such antigens
89 Improved vaccination strategies are
urgently needed to curb the global spread of this virus,
90 First, comprehensive studies are
urgently needed to define clinical correlates of protect
91 Longitudinal serological studies are
urgently needed to determine the extent and duration of
92 s commonly used to treat HG, but studies are
urgently needed to determine whether it is safer and mor
93 y glucocorticoid receptor (GR) signaling are
urgently needed to elaborate the complexity of GR signal
94 s(3,4), methods that restore performance are
urgently needed to eliminate any risk of malaria returni
95 on actions to better "manage the middle" are
urgently needed to ensure healthy functioning ecosystems
96 hanisms driving chemotherapy-induced CIPN is
urgently needed to facilitate the development of effecti
97 Therefore, it is
urgently needed to find a non-invasive targeted technolo
98 Primary data from low-resource countries are
urgently needed to guide control measures.
99 Timely detection and diagnosis are
urgently needed to guide epidemiological measures, infec
100 rse of disease and in response to therapy is
urgently needed to guide therapy decisions and to develo
101 at biospecimens from subjects with EVALI are
urgently needed to help define EVALI pathogenesis and th
102 egnant women in clinical treatment trials is
urgently needed to identify effective COVID-19 treatment
103 Further quality improvement efforts are
urgently needed to improve guideline-directed medication
104 contribute to liver discards and nonusage is
urgently needed to improve organ utilization.
105 New delivery strategies are
urgently needed to improve participation.
106 Cardioprotective strategies are
urgently needed to improve relapse risk and both short-
107 Conservation actions are
urgently needed to improve the status of freshwater spec
108 inst Mycobacterium tuberculosis infection is
urgently needed to inform strategies for novel immunothe
109 ding a resource for the scientific community
urgently needed to inform therapeutic concepts and vacci
110 Trials of novel, preventive therapies are
urgently needed to inform treatment policy and practice.
111 More research is
urgently needed to investigate how learning associated m
112 Integrated prospective studies are
urgently needed to investigate these strategies.
113 strategies and end-of-life care services are
urgently needed to prevent and tackle harms from liver d
114 A human cytomegalovirus (HCMV) vaccine is
urgently needed to protect against primary infection and
115 Further studies are
urgently needed to provide more accurate estimates of le
116 larly on the third and fourth parameters, is
urgently needed to quantify more fully the externalities
117 New therapeutic approaches are therefore
urgently needed to reduce current treatment toxicity and
118 he environment, coordinated global action is
urgently needed to reduce plastic consumption; increase
119 Effective adjuvant treatments are
urgently needed to reduce the risk of recurrence of kidn
120 Therefore, treatment strategies are
urgently needed to reverse the ICB-resistant tumor micro
121 Animal models are
urgently needed to study the pathogenesis of COVID-19 an
122 Accurate biomarkers are
urgently needed to support sepsis detection before patie
123 New therapeutics are
urgently needed to treat this infection and prevent its
124 D-19 disease, especially severe disease, are
urgently needed to understand pathogenesis and to evalua
125 specifically targeting TMEM16 CaPLSases are
urgently needed to understand these novel membrane trans
126 at a time when increased testing capacity is
urgently needed worldwide.
127 l pandemic, and safe, effective vaccines are
urgently needed(1).
128 thus, alternative therapeutic approaches are
urgently needed(2,3).
129 ents in access or alternative strategies are
urgently needed, and disparities in handwashing access s
130 New therapeutic options are
urgently needed, but regenerative therapies have remaine
131 ar level, a reverse-genetics system (RGS) is
urgently needed, but to date, no RGS had been described
132 oss-resistance are under-represented and are
urgently needed, especially for geographical regions wit
133 Thus, a replacement for IPTp-SP is
urgently needed, especially for locations with high sulf
134 Intensified management strategies are
urgently needed, for which prognostic indicators could p
135 thods for investigating human astrocytes are
urgently needed, given their critical role in the centra
136 id, affordable, and accurate diagnostics are
urgently needed, particularly in settings with limited o
137 ng scientists from different disciplines are
urgently needed, with (new) areas of interest and opport
138 Action is
urgently needed, yet well-intentioned policies designed
139 rving connectivity for entire communities is
urgently needed.
140 at are effective independent of genotype are
urgently needed.
141 f the mechanisms of SARS-CoV-2 infection are
urgently needed.
142 ession on gemcitabine-based chemotherapy are
urgently needed.
143 development of novel curative treatments is
urgently needed.
144 ding of the drivers of PNET tumorigenesis is
urgently needed.
145 osis and its ocular manifestations, is still
urgently needed.
146 n breeding and nonbreeding climate change is
urgently needed.
147 the development of new antibiotic classes is
urgently needed.
148 and biomarkers to guide decision-making are
urgently needed.
149 subtle structural difference of isomers are
urgently needed.
150 aches for rapid phenotypic ASTs for CREs are
urgently needed.
151 Thus new control strategies are
urgently needed.
152 er death in women, preventive strategies are
urgently needed.
153 Population-based data on COVID-19 are
urgently needed.
154 gies to prioritize and evaluate products are
urgently needed.
155 specific and sensitive detection methods are
urgently needed.
156 ntify them from the available literature are
urgently needed.
157 us on appropriate indications for surgery is
urgently needed.
158 stics using readily available biosources are
urgently needed.
159 s that limit unnecessary in vivo testing are
urgently needed.
160 inst coronavirus disease 2019 (COVID-19) are
urgently needed.
161 tric brain tumor for which new therapies are
urgently needed.
162 preemergent human coronaviruses (HCoVs) are
urgently needed.
163 waters at the point of sample collection are
urgently needed.
164 ined very closely and mitigating actions are
urgently needed.
165 ical settings, where the information is most
urgently needed.
166 New culture-free methods are
urgently needed.
167 daily ICU care, more high-quality data seems
urgently needed.
168 Novel COVID-19 therapeutics are
urgently needed.
169 ylaxis, a safe and effective ZIKV vaccine is
urgently needed.
170 , effective therapeutic strategies are still
urgently needed.
171 ods, other means of identifying patients are
urgently needed.
172 imal models mimicking COVID-19 in humans are
urgently needed.
173 and human testing of potential antivirals is
urgently needed.
174 prehensive understanding of these impacts is
urgently needed.
175 ID-19), efficient and specific therapies are
urgently needed.
176 vent coronavirus disease 2019 (Covid-19) are
urgently needed.
177 ity associated with CAR T-cell treatment are
urgently needed.
178 cancer mortality, with new treatment options
urgently needed.
179 hat confers sterile protection to malaria is
urgently needed.
180 testing of organically grown vegetables are
urgently needed.
181 nd well-tolerated therapeutic approaches are
urgently needed.
182 od disabilities, and an effective vaccine is
urgently needed.
183 New drugs against STNs are
urgently needed.
184 Thus, more effective therapies are
urgently needed.
185 t could prevent cancers in at-risk women are
urgently needed.
186 An effective and safe immunotherapy is
urgently needed.
187 Novel interventions are
urgently needed.
188 both inflammation and neuroregeneration are
urgently needed.
189 c potential of localized prostate cancer are
urgently needed.
190 nd deaths reported globally(2), a vaccine is
urgently needed.
191 to overcome resistance to immunotherapy are
urgently needed.
192 approaches for prevention and treatment are
urgently needed.
193 ce individualized treatment alternatives are
urgently needed.
194 t only tumour growth but also metastasis are
urgently needed.
195 the development of effective therapeutics is
urgently needed.
196 tion processes of their natural products are
urgently needed.
197 al disease for which effective therapies are
urgently needed.
198 Therefore novel drugs are
urgently needed.
199 ly assessed information on energy balance is
urgently needed.
200 se and the development of new approaches are
urgently needed.
201 A vaccine for hepatitis C virus (HCV) is
urgently needed.
202 g cognitive and behavioral symptoms are also
urgently needed.
203 nancy for which more effective therapies are
urgently needed.
204 strategies for this devastating disease are
urgently needed.
205 development of novel therapeutic targets is
urgently needed.
206 c options, and novel mechanistic targets are
urgently needed.
207 for oral squamous cell carcinoma (OSCC) are
urgently needed.
208 l landscape and tumor immune environment are
urgently needed.
209 IV vaccine that provides mucosal immunity is
urgently needed.
210 ify malonylation sites are still lacking and
urgently needed.
211 New strategies to preserve donor hearts are
urgently needed.
212 er death in women, preventive strategies are
urgently needed.
213 control while focusing on mental health are
urgently needed.
214 ysfunction for which targeted treatments are
urgently needed.
215 onventional and novel vaccine strategies are
urgently needed.
216 sia, especially the Indian subcontinent, are
urgently needed.
217 in causative agent of tuberculosis (TB), are
urgently needed.
218 w-dose/low-exposure regimens are lacking and
urgently needed.
219 n, and alternative treatment strategies were
urgently needed.
220 cy against seasonal and pandemic viruses are
urgently needed.
221 intensive management of type 2 diabetes are
urgently needed.
222 ealth, the economy and society, a vaccine is
urgently needed.
223 is dismal and new management approaches are
urgently needed.
224 tive treatment for AKI and new therapies are
urgently needed.
225 therapeutic tools to tackle glioblastomas is
urgently needed.
226 tools for monitoring treatment response are
urgently needed.
227 , interventions to mitigate transmission are
urgently needed.
228 orldwide; therefore, an effective vaccine is
urgently needed.
229 counteract multidrug-resistant gonorrhea are
urgently needed.
230 recise and early intervention strategies are
urgently needed.
231 reat coronavirus disease 2019 (COVID-19) are
urgently needed.
232 ict the infection risk of animal species are
urgently needed.
233 the aquatic environment and human health is
urgently needed.
234 rget cancers driven by BCR-Abl are therefore
urgently needed.
235 and identification of selective targets are
urgently needed.
236 tic biomarkers for prostate cancer (PCa) are
urgently needed.
237 e cure rates while minimizing toxicities are
urgently needed.
238 e, preventative and therapeutic measures are
urgently needed.
239 enesis and facilitate vaccine development is
urgently needed.Objectives: We evaluated the feasibility
240 prove neurological outcomes after stroke are
urgently needed; therefore, the present study highlights
241 anagement of noncommunicable diseases (NCDs)
urgently needs a point-of-care (PoC) testing infrastruct
242 intervention, CT angiography of the neck was
urgently performed.
243 urveillance, and capacity building should be
urgently prioritised in countries with moderate risk tha
244 lect of small, isolated habitat patches, for
urgently prioritizing their restoration, and for avoidin
245 Access to these therapies should be
urgently pursued.
246 oid further species declines, Australia must
urgently reassess the extinction vulnerability of fire-i
247 Yet these technological developments
urgently require analysis of their ethical, legal, and s
248 e first COVID-19 wave, health care providers
urgently require data to determine where elective surger
249 Modifiable risk factors
urgently require interventions to prevent increasing all
250 an lead to limb amputation or even death and
urgently require more effective treatments.
251 lled, sterile clinical settings where wounds
urgently require protection from environmental and bacte
252 macular degeneration or retinitis pigmentosa
urgently require the development of new therapeutic stra
253 (approx. 75% lower decadal mean abundance),
urgently require the identification of causal mechanisms
254 reduce systemic corticosteroid exposure are
urgently required and might be offered by a personalised
255 development of effective drugs for stroke is
urgently required as it is the 2nd largest killer in the
256 l point of view, and new I(2)-IR ligands are
urgently required for improving their pharmacological ch
257 tly validated diagnostic imaging methods are
urgently required for patients to benefit from recent th
258 gimens represent a promising strategy for an
urgently required improved tuberculosis vaccine.
259 ell-resourced countries, clinical trials are
urgently required in SSA, where highly diverse g4 and g7
260 Drugs that enhance erythropoiesis are
urgently required to decrease transfusion rates and impr
261 Trials of secondary prevention are
urgently required to determine whether this risk is modi
262 and accurate tool for FAW identification is
urgently required to establish a FAW invasion management
263 ntimicrobial susceptibility testing (AST) is
urgently required to guide effective antibiotic usages a
264 ndividual, health-care and policy levels are
urgently required to inform necessary actions to reduce
265 ching susceptibility, but that new tools are
urgently required to translate this to an operational sy
266 Preclinical tools are
urgently required which incorporate the inherent variabi
267 didates are currently in clinical trials, is
urgently required, together with a contingency strategy
268 iotics, vaccines against these pathogens are
urgently required.
269 ecular and functional imaging strategies are
urgently required.
270 the pathogenic consequences of COVID-19 are
urgently required.
271 dministration efforts, so new treatments are
urgently required.
272 Strategies to reduce recurrence are
urgently required.
273 s, innovative ways to monitor the oceans are
urgently required.
274 behaviour, but better governance models are
urgently required.
275 ng the use of antibody-based approaches, are
urgently required.
276 lorination of acetylene to vinyl chloride is
urgently required.
277 d new capture and abatement technologies are
urgently required.
278 the immunobiology of HIV-associated HCC are
urgently required.
279 address the gap in oral vaccine efficacy are
urgently required.
280 om lifestyle-based weight loss strategies is
urgently required.
281 opioid abuse and addiction is essential and
urgently required.
282 , new targets and therapeutic strategies are
urgently required.
283 ntions specific for the COVID-19 pandemic is
urgently required.
284 cobacterium tuberculosis (Mtb) infection are
urgently required.
285 an be integrated into control strategies are
urgently required.
286 nd controlling mycotoxin growth, are just as
urgently required.
287 Advances are
urgently required.
288 iratory epithelial cells; new strategies are
urgently required.Objectives: Here, we report the safety
289 terials with long-lived electron spin states
urgently requires a general theoretical formalism and co
290 This ongoing pandemic
urgently requires an accurate testing device that can be
291 g cause of neonatal morbidity and mortality,
urgently requires novel therapeutic agents.
292 Combating drug-resistant malaria
urgently requires the development of new antimalarial dr
293 in low- and middle-income countries (LMICs),
urgently requiring detailed evidence to guide the respon
294 New and clinically viable strategies are
urgently sought to breach the neoplastic barriers that p
295 al course; an effective vaccine is therefore
urgently sought.
296 ay = 12 d; mortality = 14%) were transferred
urgently to the hybrid suite.
297 falciparum malaria in this region is needed
urgently,
to prevent further spread and avoid a potentia
298 el therapeutic approaches to address it, are
urgently warranted.
299 treatment of congenital viral infections are
urgently warranted.
300 ered herpes simplex virus (HSV) therapy, are
urgently warranted.