ライフサイエンスコーパス: uric acid level

1 sma AST, salivary AST, and salivary ALT with uric acid level.

2 tion was inversely associated with the serum uric acid level.

3 enal function plays a critical role in serum uric acid levels.

4 derate wine drinking does not increase serum uric acid levels.

5 d therefore may promote a reduction in serum uric acid levels.

6 s 12% reduction (P <.0001) of initial plasma uric acid levels.

7 for every one standard deviation increase in uric acid levels.

8 reduced levels of this pool result in lower uric acid levels.

9 ors, a foundational treatment for HF, reduce uric acid levels.

10 ained enzyme activity and reduction in serum uric acid levels.

11 bsorption, and thereby, could increase serum uric acid levels.

12 increased serum magnesium levels and reduced uric acid levels.

13 n patients with less severely elevated serum uric acid levels.

14 vels significantly correlated with placental uric acid levels.

15 prevent glucose reabsorption and lower serum uric acid levels.

16 r de novo lipogenesis and leads to increased uric acid levels.

17 etabolic phenotypes, such as increased serum uric acid levels.

18 SLC2A9, a urate transporter, influences uric acid levels.

19 intakes of beer, liquor, and wine and serum uric acid levels.

20 e (35.2 [33.0-38.0] vs 33.0 [30.0-35.5] cm), uric acid level (4.9 [4.0-5.8] vs 4.5 [3.7-5.5] mg/dL),

21 (95% confidence interval: 0.04, 0.15) lower uric acid level after adjustment.

22 In a multivariable analysis, serum uric acid levels (all P<0.005) and diastolic blood press

23 evidence shows a strong correlation between uric acid level and essential hypertension, supporting i

24 antified the independent association between uric acid level and incident diabetes via Cox proportion

25 Given the relationship between uric acid level and these conditions, future studies sho

26 307 patients, 163 patients (53%) had normal uric acid levels and 144 patients (47%) had hyperuricemi

27 KTRs with SP had significantly higher uric acid levels and AGE, which may contribute to the sy

28 Allopurinol significantly reduced uric acid levels and blocked the renal functional and hi

29 ) has been shown to be associated with serum uric acid levels and gout in Asians, Europeans, and Euro

30 Higher intake of fructose increases plasma uric acid levels and higher intake of vitamin C reduces

31 ABCG2 appeared to be important modulators of uric acid levels and likely of the risk of gout.

32 To quantify the association between maternal uric acid levels and pre-eclampsia risk in a large colle

33 sitive linear association between increasing uric acid levels and presence of pre-eclampsia.

34 new light on the genes which regulate serum uric acid levels and susceptibility to gout.

35 ta on lifestyle factors that influence serum uric acid levels and the risk of gout and attempts to pr

36 ned soda and orange juice can increase serum uric acid levels and, thus, the risk of gout, but prospe

37 g patients with chronic gout, elevated serum uric acid level, and allopurinol intolerance or refracto

38 height, family history of ESRD, higher serum uric acid level, and lower measured GFR.

39 which is characterized by elevation in serum uric acid levels, and deposition of uric acid crystals i

40 d hemoglobin, albuminuria, triglycerides and uric acid levels, and worse measured glomerular filtrati

41 variance with IR; insulin, triglyceride, and uric acid levels; and diastolic blood pressure.

42 ell count, blood glucose, D-dimer, and serum uric acid levels; and were more likely to have metabolic

43 d, suggesting that the genes associated with uric acid level are also associated with these phenotype

44 studies have suggested that increased serum uric acid levels are a risk factor for cardiovascular mo

45 Serum uric acid levels are an independent predictor of death i

46 Higher uric acid levels are associated with an increased risk f

47 the breakdown of purines, and elevated serum uric acid levels are associated with higher risk of hype

48 Maternal uric acid levels are associated with risk of pre-eclamps

49 osodium urate crystals in joints when plasma uric acid levels are chronically elevated beyond the sat

50 Reductions in serum uric acid levels are clinically relevant.

51 These results indicate that, although uric acid levels are elevated in the airways of NO2-expo

52 Epidemiologic studies suggest that serum uric acid levels are heritable.

53 Our data suggest that increased serum uric acid levels are independently and significantly ass

54 Current evidence supports use of serum uric acid level as a biomarker for diagnosis of essentia

55 r adjusting for age, the difference in serum uric acid levels as compared with no intake increased wi

56 A modest rise in uric acid levels beginning early after donation, and a s

57 After adjusting for age, the differences in uric acid levels between the extreme quintiles of intake

58 e long been suspected of affecting the serum uric acid level, but few data are available to support o

59 evels and higher intake of vitamin C reduces uric acid levels, but whether these nutrients are indepe

60 d that for each 59.48-micromol/L increase in uric acid level, cardiovascular mortality and ischemic h

61 every 4 weeks for 6 months resulted in lower uric acid levels compared with placebo.

62 ctions, and plasma glucose levels, the serum uric acid level continued to predict the risk of death (

63 eactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores,

64 these effects were stronger among men (e.g. uric acid level difference per copy of the minor allele,

65 with pharmacological treatments that reduced uric acid levels either by blocking its synthesis or hyd

66 difference = 1.7, 95% CI: -0.1, 3.4), plasma uric acid levels (for those born early preterm, differen

67 for incident hyperuricemia (defined as serum uric acid level >/=7.0 mg/dL) according to prespecified

68 ted stage 1 essential hypertension and serum uric acid levels > or = 6 mg/dL.

69 interest was hyperuricemia, defined as serum uric acid levels >/=6 mg/dL.

70 tricular ejection fraction </=40%, and serum uric acid levels >/=9.5 mg/dL to receive allopurinol (ta

71 s, low serum calcium (< 8.4 mg/dL), and high uric acid levels (> 7.0 mg/dL) were also linked to incre

72 Increased serum uric acid levels had a positive relationship to cardiova

73 arch is needed to determine whether lowering uric acid level has any beneficial effects on stroke.

74 Serum uric acid levels have been linked to many ageing illness

75 1c) (HbA(1c)), alanine aminotransferase, and uric acid levels; hypoglycemic drug use; compliance; and

76 ein intake was not associated with the serum uric acid level in multivariate analyses (P = 0.74 for t

77 as to evaluate the prognostic value of serum uric acid levels in a large cohort of men and women at h

78 lationship between dietary factors and serum uric acid levels in a nationally representative sample o

79 purinol effectively and safely lowered serum uric acid levels in adults with stage 3 CKD and asymptom

80 e incidences or mortalities related to serum uric acid levels in adults.

81 Ingestion of allopurinol rescued uric acid levels in Aprt-deficient mutants but not neuro

82 CSA-OA treated rats had higher uric acid levels in association with more severe arterio

83 etween maternal serum fructose and placental uric acid levels in humans.

84 Moreover, plasma uric acid levels in mice fed the WD were decreased after

85 egloticase is an enzyme used to reduce serum uric acid levels in patients with chronic, treatment-ref

86 lic blood pressure, triglycerides, and serum uric acid levels in the CsA reduction group.

87 ed cell systems and in the intestine in vivo Uric acid levels in the gut lumen increased in response

88 and non-human primates and normalized serum uric acid levels in uricase-deficient mice.

89 (15)NH4Cl based on a significant increase in uric acid levels in whole-body extracts and a reduction

90 four SLC2A9 SNPs, previously associated with uric acid levels, in approximately 1000 Scots: the Lothi

91 The serum uric acid level increased with increasing total meat or

92 the subject's health status, CK activity and uric acid levels increased significantly between the beg

93 Serum uric acid levels increased with increasing beer or liquo

94 nction and cohort; therefore, elevated serum uric acid level is a modest, independent risk factor for

95 Elevated serum uric acid level is associated with obesity, insulin resi

96 py number polymorphisms (CNPs) contribute to uric acid levels is unknown.

97 Benziodarone reduced uric acid levels less effectively and only partially imp

98 behavioral disturbances, including increased uric acid levels, locomotor impairments, sleep alteratio

99 nd meta-analysis of cohort studies measuring uric acid levels < 20 weeks of gestation was performed t

100 d, then this study could suggest that higher uric acid levels may be associated with increased perfor

101 gies, including myocardial infarction, serum uric acid levels, mean platelet volume, aortic root size

102 s who were aged 25 to 74 years and had serum uric acid level measurements at baseline.

103 en per 1,000 person-years according to serum uric acid levels of <5.0, 5.0-5.9, 6.0-6.9, 7.0-7.9, and

104 was limited to patients with baseline serum uric acid levels of 8 mg/dL or less.

105 Primary end point was plasma uric acid levels of less than 6.0 mg/dL in months 3 and

106 sociated with a 0.24-mg/dL increase in serum uric acid level (P = 1.37 x 10(-80)) and a 1.75-fold inc

107 1142 was significantly associated with serum uric acid levels (P = 2.37 x 10(-67), P = 3.98 x 10(-5),

108 , whereas both serum magnesium (P<0.001) and uric acid levels (P=0.008) improved.

109 ey suggested that these factors affect serum uric acid levels parallel to the direction of risk of go

110 dase inhibitor allopurinol reduced placental uric acid levels, prevented placental inefficiency, and

111 eys, reduced oxidative stress, lowered serum uric acid level, reduced glomerular hyperfiltration and

112 s to tight and tissue-specific regulation of uric-acid levels, revealing a previously unknown role fo

113 nd the allopurinol groups had baseline serum uric acid levels (SDs) of 8.7 (1.6) mg/dl and 8.3 (1.4)

114 e mechanism of association of elevated serum uric acid level (SUA) with cardiovascular disease (CVD)

115 least once every other day had a lower serum uric acid level than did those who did not consume yogur

116 lk 1 or more times per day had a lower serum uric acid level than did those who did not drink milk (m

117 In this regard, humans have higher uric acid levels than most mammals due to a mutation in

118 meat and sugary beverages would help reduce uric acid levels, the risk of gout, insulin resistance,

119 For each 1-mg/dl increase in the serum uric acid level, there was a 39% increase in the risk of

120 Upon further adjustment for uric acid levels, there was modest attenuation of the as

121 ildren, presenting the possibility for serum uric acid level to serve as a biomarker for diagnosis an

122 It is unclear whether adding uric acid levels to the assessment of cardiovascular ris

123 Experimentally increasing uric acid levels using a uricase inhibitor causes system

124 t of individual alcoholic beverages on serum uric acid levels varies substantially: beer confers a la

125 s 1664+/-81 dyne x s x cm(-5), average serum uric acid level was 7.5+/-0.35 mg/dL, and average peak o

126 Uric acid level was associated with diabetes even after

127 e-based logistic regression models, baseline uric acid level was associated with increased risk for i

128 n between duration of diabetes and change in uric acid level was examined via linear regression.

129 ent for cardiovascular disease risk factors, uric acid level was no longer associated with coronary h

130 en, after adjustment for age, elevated serum uric acid level was not associated with increased risk f

131 In women, after adjustment for age, uric acid level was predictive of coronary heart disease

132 to minidose aspirin and its effect on serum uric acid levels was addressed.

133 n, and serum cholesterol, blood glucose, and uric acid levels, was examined.

134 Increased blood uric acid levels were also associated with worse scores

135 of stroke incidence and mortality with serum uric acid levels were calculated.

136 Serum uric acid levels were determined in all patients seen fo

137 e in both men and women increased when serum uric acid levels were in the highest quartile compared w

138 eart catheterization was performed and serum uric acid levels were measured in all patients.

139 Blood uric acid levels were related to the intracellular adeny

140 However, creatinine and uric acid levels were significantly higher in the BS-NPs

141 At the end of the study period, serum uric acid levels were significantly reduced in the vitam

142 Uric acid levels were significantly reduced with allopur

143 Baseline characteristics, including serum uric acid level, were similar among treated and untreate

144 We examined both the association of uric acid level with incident diabetes and the change in

145 tcomes is probably due to the association of uric acid level with other risk factors.

146 We evaluated whether lowering serum uric acid levels with allopurinol improves endothelial d

147 with reduced ejection fraction and elevated uric acid levels, xanthine oxidase inhibition with allop