ライフサイエンスコーパス: uridine diphosphate

1 are activated by endogenous ATP, UTP, and 5'uridine-diphosphate.

2 Selected compounds tested at the two uridine diphosphate-activated P2Y receptor subtypes show

3 nd membrane translocation of hyaluronan from uridine diphosphate-activated precursors(3,4).

4 Tps1) in unliganded form and in complex with uridine diphosphate and glucose-6-phosphate.

5 bound with uridine diphosphate or with both uridine diphosphate and myricetin were determined at 2.1

6 onfidence interval identified four predicted uridine diphosphate-dependent glucosyltransferases.

7 Here, we present UGT76B1 as a uridine diphosphate-dependent glycosyltransferase (UGT)

8 l tolerance of galactosyltransferases toward uridine-diphosphate-galactosamine (UDP-GalN), which is n

9 sed on a wild-type galactosyltransferase and uridine diphosphate galactose (UDP-Gal) for global and s

10 rase produces efficient galactosylation when uridine diphosphate-galactose is added, affording a pote

11 O-GlcNAcylation requires uridine diphosphate-GlcNAc, a precursor responsive to nu

12 in the glycosyltransferase active site above uridine diphosphate-GlcNAc.

13 for production of the donor nucleotide-sugar uridine-diphosphate-GlcNAc (UDP-GlcNAc) by deletion of t

14 s and was genotyped for the TA repeat at the uridine diphosphate glucononosyltransferase-lA1 promoter

15 sylgalactosylhydroxylysine on collagen using uridine diphosphate glucose (UDP-glucose) but no other U

16 46.82 mukat/Kg protein toward phloretin and uridine diphosphate glucose (UDPG) at an optimal tempera

17 Using adenosine diphosphate glucose and uridine diphosphate glucose as proxies for labeling of G

18 tic data, revealed that H23 bound within the uridine diphosphate glucose binding pocket of yGsy2p.

19 of ceramide metabolism and transport genes: uridine diphosphate glucose ceramide glucosyltransferase

20 ose is produced from glucose 6-phosphate and uridine diphosphate glucose in a two-step process, and r

21 Uridine diphosphate glucose, a proxy for cytosolic G6P,

22 ophosphorylcholine, myo-inositol, imidazole, uridine diphosphate glucose, isocitrate, lactate, and fu

23 Synthesis depends on uridine diphosphate glucose, Mg(2+), and cyclic diguanos

24 On the other hand, flux through the hepatic uridine-diphosphate- glucose pool did not differ between

25 lucose transporter 4; 2) inhibited cytosolic uridine diphosphate-glucose elevation that would occur w

26 osyltransferase that converts naringenin and uridine diphosphate-glucose to naringenin-7-O-B-d-glucos

27 Two uridine diphosphate glucosyltransferases were functional

28 Uridine diphosphate glucunosyltransferases (UGTs) metabo

29 transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the c

30 tabolites produced by cytochrome P450 and/or uridine diphosphate glucuronosyl transferases were simul

31 Uridine diphosphate glucuronosyltransferase (EC 2.4.1.17

32 3A1 and CYP2B1/2, testosterone/4-nitrophenol uridine diphosphate glucuronosyltransferase (UDPGT), and

33 ance of bilirubin requires the expression of uridine diphosphate glucuronosyltransferase (UGT) 1A1; w

34 Mutations in the uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1)

35 103-glucuronide (TAS-103-G) predominantly by uridine diphosphate glucuronosyltransferase isoform 1A1

36 (benzoate) can be explained by deletion of a uridine diphosphate glucuronosyltransferase.

37 the linkage region encodes hepatic bilirubin uridine diphosphate-glucuronosyltransferase (UGT1A1).

38 We used rs6742078 located in the uridine diphosphate-glucuronosyltransferase locus as an

39 Uridine diphosphate-glucuronosyltransferase-1A1 deficien

40 Uridine diphosphate-glucuronosyltransferase-1A1 deficien

41 abolite, SN-38, is glucuronidated by hepatic uridine diphosphate glucuronosyltransferases (UGTs).

42 Phase I (cytochromes P-450) and phase II (uridine diphosphate glucuronosyltransferases) drug-metab

43 formiminotransferase cyclodeaminase, and the uridine diphosphate glucuronosyltransferases, whereas al

44 sport proteins as well as other enzymes (eg, uridine diphosphate-glucuronosyltransferases, cytochrome

45 lation, no heritable factors associated with uridine diphosphate glucuronyl transferase 2B7 metabolis

46 Despite the importance of uridine diphosphate glycosyltransferase (UGT) enzymes in

47 oint LOD score is located 1 cM away from the uridine diphosphate glycosyltransferase 1 (UGT1A1) gene.

48 Candidate uridine-diphosphate glycosyltransferase genes (UGTs) wer

49 DTGs, we conducted a genome-wide analysis of uridine diphosphate glycosyltransferases (UGTs) and iden

50 ome for sequences with similarity to terpene URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASES (UGTs) from Ara

51 Notably, several TFs targeted genes encoding uridine diphosphate glycosyltransferases (UGTs), crucial

52 d functions, is controlled by specific plant uridine diphosphate glycosyltransferases (UGTs).

53 Four candidate uridine diphosphate glycosyltransferases were expressed

54 sis branch in M. truncatula In addition, two uridine diphosphate glycosyltransferases, UGT73F18 and U

55 chrome P450 enzymes, prenyltransferases, and uridine diphosphate glycosyltransferases.

56 It is mediated by uridine-diphosphate glycosyltransferases (UGTs), that ac

57 iphosphate N-acetylhexosamine (UDP-HexNAc)]/[uridine diphosphate hexose (UDP-hexose)] ratio exhibited

58 ptor with a high affinity for the nucleotide uridine diphosphate, is an important endogenous inhibito

59 vidence supports further work on the role of uridine diphosphate N -acetylglucosamine as a critical n

60 samine biosynthesis pathway; its end product-uridine diphosphate N -acetylglucosamine-drives the rapi

61 lly, and the stereochemistry was assigned as uridine diphosphate N'-diacetylbacillosamine (UDP-diNAcB

62 e timecourses of (13)C isotopologue data for uridine diphosphate N-acetyl-D-glucosamine (UDP-GlcNAc)

63 )-dependent oxidation of the 3'' position of uridine diphosphate N-acetyl-D-glucosamine (UDP-GlcNAc),

64 Purified uridine diphosphate N-acetylenolpyruvylglucosamine reduc

65 uridine diphosphate N-acetylglucosamine and uridine diphosphate N-acetylgalactosamine, leading to th

66 osamine biosynthetic pathway (HBP) generates uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) for

67 xosamine biosynthesis pathway (HBP) produces uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a

68 Glucose and glutamine are precursors of uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a

69 e fate of the chitin-biosynthesis precursor, uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), wa

70 ructose 6-phosphate to eventually synthesize uridine diphosphate N-acetylglucosamine (UDP-GlcNAc).

71 nsferase pp-alpha-GanT2 able to utilize both uridine diphosphate N-acetylglucosamine and uridine diph

72 ich catalyzes a key step in the synthesis of uridine diphosphate N-acetylglucosamine, which is requir

73 fect on the biosynthetic reactions involving uridine diphosphate N-acetylglucosamine.

74 pyridyl)-benzimidazole and MurA complexed to uridine diphosphate N-acetylglucosamine.

75 atin activity and binding of the sugar donor uridine diphosphate N-acetylglucosamine.

76 decreased, whereas the distribution of the [uridine diphosphate N-acetylhexosamine (UDP-HexNAc)]/[ur

77 Uridine diphosphate N-acetylmuramate:L-alanine ligase (E

78 ted by decreased enzyme activity and reduced uridine diphosphate-N-acetyl-D-glucosamine, along with d

79 GlcNAc) levels are modulated by two enzymes: uridine diphosphate-N-acetyl-D-glucosamine:polypeptidylt

80 resulting in a 70:30 ratio of UDP-GlcNAc to uridine diphosphate-N-acetylgalactosamine (UDP-GalNAc),

81 cosylation catalyzed by distinct recombinant uridine diphosphate-N-acetylgalactosamine:polypeptide N-

82 With uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) as

83 nce studies indicated thatlymphostatin binds uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) but

84 ally characterized to show that it encodes a uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) C4

85 dramatically reduced intracellular levels of uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc), a

86 mine biosynthetic pathway (HBP), to increase uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc).

87 ltransferase that catalyzes the formation of uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc).

88 the mammalian Golgi membrane transporter for uridine diphosphate-N-acetylglucosamine by phenotypic co

89 domain contains a deep cavity for binding of uridine diphosphate-N-acetylglucosamine, and the surroun

90 ble HeLa cell line that overexpresses murine uridine diphosphate-N-acetylglucosaminyl transferase (OG

91 be the kinetic mechanism of Escherichia coli uridine diphosphate-N-acetylmuramate:L-alanine ligase (U

92 ADP, uridine diphosphate-N-acetylmuramoyl-L-alanine (UNAMA),

93 The structures of UGT78G1 bound with uridine diphosphate or with both uridine diphosphate and

94 e to ADP (e.g., P2Y(1), P2Y(3), P2Y(12)) and uridine diphosphate (P2Y(6)).

95 he P2Y(6) receptor (P2Y(6)R) is activated by uridine diphosphate released by neurons, inducing microg

96 iphosphate > 5'uridine-triphosphate > or = 5'uridine-diphosphate, supports a P2Y1 receptor (R).

97 ferase in its apo form and in complexes with uridine diphosphate (UDP) and the disaccharide product.

98 UMP phosphorylation to uridine diphosphate (UDP) by UMP KINASEs (UMKs) is requi

99 By developing an in vivo uridine diphosphate (UDP) fluorescent sensor, GRAB(UDP1.

100 Uridine diphosphate (UDP) galactose, a pivotal compound

101 is and then subsequently characterized seven uridine diphosphate (UDP) glycosyltransferases (UGTs) fr

102 zes the reversible conversion of sucrose and uridine diphosphate (UDP) into fructose and UDP-glucose,

103 onse to cysteinyl leukotrienes (cys-LTs) and uridine diphosphate (UDP) that is blocked by cys-LT rece

104 sponse to cys-LTs and the nucleotide ligand, uridine diphosphate (UDP), without increasing their surf

105 Uridine diphosphate (UDP)-activated purinergic receptor

106 d by a series of glycosylations catalyzed by uridine diphosphate (UDP)-dependent glucosyltransferases

107 SLC35A2 encodes a uridine diphosphate (UDP)-galactose transporter essentia

108 The enzyme uridine diphosphate (UDP)-galactose-4-epimerase, encoded

109 to biosynthesize the nucleotide-sugar donor uridine diphosphate (UDP)-GalNAzMe from a sugar-1-phosph

110 o GlcNAc-1-phosphate during the synthesis of uridine diphosphate (UDP)-GlcNAc, a sugar nucleotide cri

111 Microsomal uridine diphosphate (UDP)-glucuronosyltransferase (UGT)

112 ic steps of this pathway involve a series of uridine diphosphate (UDP)-linked peptidoglycan intermedi

113 ltransferase MurU catalyzes the synthesis of uridine diphosphate (UDP)-MurNAc, a crucial precursor of

114 y) are diseases in which the activity of the uridine diphosphate (UDP)-N-acetylglucosamine:lysosomal

115 Silencing the Uridine diphosphate (UDP)-rhamnosyltransferase gene UGT9

116 are responsible for synthesis of an uncommon uridine diphosphate (UDP)-sugar (PglD, PglC, and PglB-ac

117 Unnatural uridine diphosphate (UDP)-sugar donors, UDP-4-deoxy-4-fl

118 ition of ENO2 expression or activity reduced uridine diphosphate (UDP)-sugar pools, attenuated the ac

119 ls (hMCs) to stimulation with the nucleotide uridine diphosphate (UDP).

120 gi metabolome and revealed the enrichment of uridine-diphosphate (UDP) sugars and their derivatives,

121 ferred by GlmU to afford their corresponding uridine diphosphate(UDP)-sugar nucleotides.

122 Mixtures composed of uridine monophosphate, uridine diphosphate, uridine triphosphate, and their non