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1 brucei RET2 apoenzyme and its complexes with uridine nucleotides.
2 ne nucleotides but is largely independent of uridine nucleotides.
3 2 receptor, is activated by both adenine and uridine nucleotides.
4 the extracellular metabolism of adenine and uridine nucleotides.
5 the pharmacological activities of these two uridine nucleotides.
6 and contains negligible amounts of NADH and uridine nucleotides.
8 sults demonstrate differential regulation of uridine nucleotide-activated P2Y4-R and P2Y6-R and indic
9 e relative nucleotide selectivities of these uridine nucleotide-activated receptors have not been est
10 ciple was used to develop stacked and folded uridine nucleotide analogs that showed highly quenched f
12 sed the safety and efficacy of sofosbuvir, a uridine nucleotide analogue, in treatment-naive patients
13 their respective specificity for adenine and uridine nucleotides and di- and triphosphates, these res
14 es of being photolabeled by vanadate-trapped uridine nucleotides and immunoreactive with a monoclonal
15 tides containing single 2'-aminocytidine or -uridine nucleotides annealed to DNA or RNA targets under
18 eaves mitochondrial mRNA, inserts or deletes uridine nucleotides at specific positions and re-ligates
20 nusual agonist rank order was revealed, with uridine nucleotides being more potent than adenosine nuc
21 ich most likely explain the observation that uridine nucleotides bind more tightly to epimerase/NADH
22 alyze deamination of cytidine nucleotides to uridine nucleotides (C-to-U) in single-strand DNA substr
23 y binding to specific sites on pyr mRNA in a uridine nucleotide-dependent manner and altering the fol
24 dine nucleotide (pyr) operon by binding in a uridine nucleotide-dependent manner to specific sites on
26 een cloned that are selectively activated by uridine nucleotides, direct demonstration of the release
27 ith the terminal deoxynucleotidyltransferase-uridine nucleotide end-labeling technique on tissue sect
28 ding on the RNA tested and the assay method; uridine nucleotides enhanced RNA binding, but guanosine
30 iptional RNA editing that inserts or deletes uridine nucleotides in many mitochondrial pre-mRNAs.
32 active, abortive complexes designated E.NADH.uridine nucleotide, in which the uridine nucleotide may
33 the charge-transfer band are altered by the uridine nucleotide-induced conformational change in this
34 aracterized by the insertion and deletion of uridine nucleotides into otherwise nontranslatable messe
35 he postulate that NAD+ activation induced by uridine nucleotides is brought about by a conformational
37 ated E.NADH.uridine nucleotide, in which the uridine nucleotide may be UDP-glucose, UDP-galactose, or
38 extracellular interconversion of adenine and uridine nucleotides plays a key role in defining activit
39 ngs to the class of 2'-deoxy-2'-spirooxetane uridine nucleotide prodrugs which are known as inhibitor
40 ressed in C6-2B cells and to account for the uridine nucleotide responses originally identified in th
41 rovided the first indication that a class of uridine nucleotide-responsive receptors might exist.
42 lioma cells and by the recent cloning of two uridine nucleotide-responsive receptors, the P2Y6 recept
43 ne, catalyzes the esterification of modified uridine nucleotides, resulting in the formation of 5-met
44 hermore, the P2Y6 receptor, which displays a uridine nucleotide selectivity essentially identical to
46 ctivity essentially identical to that of the uridine nucleotide-specific receptor in C6-2B cells, was
47 sis was confirmed by our identification of a uridine nucleotide-specific receptor on C6-2B rat glioma
48 le of topo I at the 3' phosphodiester of the uridine nucleotide to generate a covalent enzyme-DNA add
49 owed the intracellular pools of cytidine and uridine nucleotides to be manipulated by the composition
52 the production of both PGE(2) and IL-6, the uridine nucleotide, UTP, stimulated PGE(2) but not IL-6
53 Our work reveals that replacing a single uridine nucleotide with Psi in an mRNA codon impedes ami
54 ce sites while adapting to both cytidine and uridine nucleotides with nearly equivalent frequencies.