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1  in the biosynthesis of the azoxy antibiotic valanimycin.
2 difaciens MG456-hF10 produces the antibiotic valanimycin, a naturally occurring azoxy compound.
3 and the lyase VlmK during the final steps of valanimycin biosynthesis are established as well.
4 experiments suggest that the role of VlmL in valanimycin biosynthesis is to produce seryl-tRNA, which
5 lor SerRS, is hypothesized to play a role in valanimycin biosynthesis, because the vlmL gene resides
6           To investigate the role of VlmL in valanimycin biosynthesis, VlmL and SvsR have been overpr
7 tions to elucidate the role of seryl-tRNA in valanimycin biosynthesis.
8 evealed that the VlmA protein encoded by the valanimycin biosynthetic gene cluster catalyzes the tran
9                       A novel feature of the valanimycin biosynthetic gene cluster is the presence of
10 ons led to the cloning and sequencing of the valanimycin biosynthetic gene cluster, which was found t
11 is, because the vlmL gene resides within the valanimycin biosynthetic gene cluster.
12                     Sequence analysis of the valanimycin biosynthetic genes provides relatively few c
13 this enzyme is to provide seryl-tRNA for the valanimycin biosynthetic pathway.
14 t the conversion of valanimycin hydrate into valanimycin by S. viridifaciens requires both the vlmJ a
15                    An unusual feature of the valanimycin gene cluster is that four genes involved in
16 on experiments defined the boundaries of the valanimycin gene cluster, which appears to contain 14 ge
17                    While the biosynthesis of valanimycin has been partially characterized, how the az
18 s the isolation and structure elucidation of valanimycin hydrate from vlmJ and vlmK mutants of S. vir
19 al studies have shown that the conversion of valanimycin hydrate into valanimycin by S. viridifaciens
20 ent phosphorylation of the hydroxyl group of valanimycin hydrate prior to VlmK-catalyzed dehydration.
21                               The antibiotic valanimycin is a naturally occurring azoxy compound isol
22                               The antibiotic valanimycin is a naturally occurring azoxy compound prod
23                                              Valanimycin is an azoxy-containing natural product isola
24 cursor incorporation experiments showed that valanimycin is derived from l-valine and l-serine via th
25      Detailed investigations have shown that valanimycin is derived from L-valine and L-serine via th
26                                              Valanimycin is known to be derived from valine and serin
27         Previous studies have shown that the valanimycin producer Streptomyces viridifaciens contains
28                                          The valanimycin producer Streptomyces viridifaciens contains
29                   Subcloning of DNA from the valanimycin-producing cosmid has led to the identi-ficat
30 plified by PCR from a genomic library of the valanimycin-producing organism, Streptomyces viridifacie
31 f a 22 kb segment of DNA sufficient to allow valanimycin production in S. lividans TK24.
32 iridifaciens DNA was isolated that conferred valanimycin production upon Strepto-myces lividans TK24.
33  an amino acid decar-boxylase gene (vlmD), a valanimycin resistance gene (vlmF ), at least two regula
34 volved in the biosynthesis of the antibiotic valanimycin was discovered in a Streptomyces strain.
35                          The biosynthesis of valanimycin was thus fully reconstituted in vitro using