ライフサイエンスコーパス: validate

1 gainst PKCdelta or SOM that we developed and validated.

2 d bleeding risk models have been created and validated.

3 al roles of most of these genes remain to be validated.

4 Only one model had been externally validated.

5 ve genes; results for only 11 genes could be validated.

6 he measurements of various CC parameters are validated.

7 s, but none of these questionnaires is fully validated.

8 A CDG with high sensitivity was derived and validated.

9 The assay was developed and technically validated.

10 are largely novel and yet to be extensively validated.

11 according to Shivappa et al. method using a validated 125-item FFQ.

12 intensity of pruritus (VAS) and improved the validated 5D-Itch questionnaire (P = .002 vs placebo).

13 5.6x10(-8) and HBB rs344, P=9.3x10(-11)) and validated 8 loci for urine albumin-to-creatinine ratio p

14 Here, we develop and validate a biomathematical framework encompassing drug r

15 y acquired experimental data, we present and validate a computational workflow based on kallisto and

16 Here, we identify and functionally validate a CRC 'trio' constituted by three transcription

17 gimens are needed.Objectives: To develop and validate a deep learning method to improve the managemen

18 Our goals in this study were to (i) validate a LC-MS method that assesses HBP flux as UDP-Gl

19 This article aims to develop and validate a multivariate model for quantifying Robusta-Ar

20 Our goal was to validate a new predictive model for BPD severity that in

21 We derive and validate a novel and analytic method for estimating the

22 These findings validate a novel animal model of nicotine vapor self-adm

23 Here, we present and validate a novel method of MRI velocity-encoding combine

24 We sought to construct and validate a patient-reported outcome measure for screenin

25 ata, compare different synchronous areas and validate a previously conjectured scaling law.

26 The aim of this study was to develop and validate a risk prediction tool for trauma-induced coagu

27 tasets in order to develop, train, test, and validate a robust classifier to identify medulloblastoma

28 authors sought to systematically screen and validate a wide range of potential modifiable factors fo

29 In this study we created and validated a multiscale mathematical model to investigate

30 Accordingly, we developed and validated a prognostic index (PIUKALL) that integrates m

31 . aureus-mediated osteomyelitis, and then we validated a proof of concept for the lateral flow assay

32 We validated a subset of the observed associations in an in

33 ferred on a limited number of experimentally validated A. thaliana interactions and were adapted to f

34 This work introduces and validates a 15-minute or faster assay for germinable end

35 As a resource, we have generated and validated AAV-PA-Cre 3.0 as well as two mouse lines that

36 The optimized method was validated according to authorities' guidelines and requi

37 uantitation of esketamine were developed and validated according to International Conference on Harmo

38 oarse-grained molecular dynamics simulations validated against atomistic simulations, we explore the

39 The model was validated against surgical data.

40 The method was validated against the gold standard Limulus Amoebocyte l

41 Asthma was based on a validated algorithm using asthma diagnoses from hospital

42 We assigned phenotype status using a validated algorithm.

43 RI technique, there is a need to develop and validate alternative parameters to assess liver fat.

44 We validate an association between maize and Dyella japonic

45 We externally validated an electronic health record AF (EHR-AF) score

46 demonstrating how it might be used to cross-validate and compare in vivo radiologic imaging with ex

47 The modified method was validated and met the performance criteria required by t

48 Expanding on a validated and published nongenetic, CF-like sheep model,

49 METAGENOTE then compiles, validates and manages the submission through an easy-to-

50 (NCBI) previously made available a tool for validating and annotating influenza virus sequences that

51 Here we introduce, validate, and apply a magnetic device that generates a u

52 he National Lung Screening Trial, internally validated, and externally tested on cohorts from two aca

53 deep neural network, CV19-Net, was trained, validated, and tested on chest radiographs in patients w

54 protection against human tuberculosis and a validated animal model of the disease, tools to facilita

55 A two-variable classifier yielded a cross-validated area under the receiver operating characterist

56 ase chain reaction assay for M. leprae, were validated as clinical diagnostic assays according to Cli

57 rug discovery has been hampered by a lack of validated assays to establish treatment efficacy in pre-

58 The findings were validated at a 3-year follow-up (N = 59) of the same ind

59 The 5-fold cross-validated AUC for glaucoma versus nonglaucoma from logis

60 Serum thromboxane B2 (sTXB2), a validated biomarker of platelet COX-1 activity, and urin

61 Prospective studies are required to validate biomarkers.

62 We first validated blood flow simulations against in vitro measur

63 The 3D printed MALDI targets were validated by analysis of different types of bacteria and

64 , FIGF, CTSK, and MLANA and novel biomarkers validated by aptamer screening, ELISA, and immunofluores

65 The 200 ns simulations, validated by available experimental data, reveal process

66 ent and the other Na(+)-dependent, which was validated by biochemical analyses.

67 tained from the PCR method were successfully validated by chromatographic mycotoxin and microscopy an

68 l cell sorting in wild type C57BL/6 mice was validated by comparative transcriptome analysis with ret

69 red with morphologic imaging (CT or MRI) and validated by histopathology.

70 Protein expression of selected genes was validated by immunofluorescence on retinal wholemounts a

71 Versatility was further validated by implementing the biosensors in multiple con

72 olocalized with EGFP(Vgat) neurons, which we validated by in situ hybridization for Vgat mRNA.

73 ted to generate this model, and functionally validated by in vitro, ex vivo and in vivo techniques.

74 Candidate genes were validated by independent gene mutation.

75 The resulting markers were validated by linking them with clinical outcomes (visual

76 The results were validated by liquid chromatography-mass spectrometry (LC

77 The in-vivo metabolic data were validated by mitochondrial respirometry, enzyme activity

78 h numbers within cell protrusions, a finding validated by mitochondrial staining.

79 This aspect was then experimentally validated by modulating the zeta potential of the detect

80 eproducibility and safety of the method were validated by MRI and histology.

81 of the viral polymerase (L) protein that was validated by photoaffinity labelling-based target mappin

82 ere exceptionally accurate, as independently validated by secondary testing.

83 predictions by these empirical equations are validated by several MOFs with an average deviation of 5

84 These changes are validated by targeted and global experimental analysis.

85 The assay accuracy was validated by titration of 10-80% mixture of acetylated/n

86 The predictive effectivity of the model was validated by using 67 cancers from WCH and 47 cancers fr

87 The method is validated by using both negative-staining (NS) and cryo-

88 The analytical method has been validated by verifying the different performance criteri

89 nterference, RNAscope, and image analysis to validate cell-type-specific cis-regulatory elements in h

90 We validate ChromA on multiple technologies and biological

91 Correlation with validated clinical scores supported pathophysiological r

92 AHQ is a patient-informed, psychometrically-validated, clinical instrument for measuring, quantifyin

93 s for HHV-8 is currently challenging with no validated commercial serology kits available.

94 under the receiver operator curve and model validated confirmed with and fivefold cross-validation.

95 only detects 18% of all histopathologically validated cortical lesions.

96 A highly validated CSC model (FGbeta(3) cells) was used to test a

97 Using partially validated data from a human immunodeficiency virus cohor

98 Here, validated, defined neoantigens, predicted neoepitopes, a

99 expression in an independent adult AD cohort validated differential expression of STS PC1 proteins in

100 s, such as selection of ideal TCRs targeting validated epitopes with well-characterized cancer cell e

101 FM and LM were predicted using validated equations and compared with dual-energy x-ray

102 cific alternative splicing of a functionally validated exon in normal and disease states - and reveal

103 The computational results were validated experimentally (up to 92:8 er), providing anot

104 he importance of these in-silico findings is validated experimentally by site-directed mutagenesis of

105 Early pregnancy diets were assessed using a validated FFQ from which energy-adjusted Dietary Inflamm

106 on on dietary nicotine intake from 1986 from validated FFQs.

107 Index 2010 (AHEI-2010) were calculated using validated food-frequency questionnaires.

108 The results are experimentally validated for a given geometry over a wide range of Reyn

109 The method was validated for analysis of selected ethyl esters present

110 Background Chest radiography has not been validated for its prognostic utility in evaluating patie

111 on of fifteen cannabinoids was developed and validated for multiple matrices.

112 g human behavior are typically developed and validated for single time-point assessment, in highly co

113 The methodology was validated for tea, apple-based beverage and pineapple ju

114 A HPLC-UV/FLD method was validated for the quantification of six polyethylene ter

115 rs as measured via the model simulations and validated from human GBM patient histology.

116 ation, and vulvar pressure) to establish and validate generalizable pain representations.

117 series will be invaluable in calibrating and validating global earth system models to project changes

118 ing FACS coupled with quantitative RT-PCR, a validated GLP-1R antibody, and flow cytometry to quantif

119 These findings validate GSTO1 as a therapeutic target in cancer and imp

120 The utility of 6qcNIR was validated in a busy real-world clinical setting, and cli

121 Models were externally validated in a cohort of intubated pediatric acute respi

122 that this latent phenotyping model has been validated in a general population sample, it can be exte

123 0% overall survival at 69 months), which was validated in a large independent cohort.

124 o predictions of relative virulence that are validated in a mouse infection model.

125 nsus, and their performance has not yet been validated in a well-defined cohort of patients with PG.

126 The anatomic findings were validated in an independent cohort of acute stroke patie

127 iomarkers and selected biomarker models were validated in an independent patient group.

128 monly used vitamers, was developed and fully validated in analytical ranges, adjusted to their recomm

129 S growth and survival in human blood and was validated in another M1T1 GAS strain, 5448.

130 The concept of dormancy has been validated in C. neoformans from both epidemiological and

131 parameters gamma and beta of the model were validated in continuous wash experiments of chopped iceb

132 a framework for a polygenic risk score to be validated in future studies.

133 Integrated models, if validated in independent populations, could provide nove

134 potentials (LFPs) at implanted DBS leads was validated in patients with neurological disorders.

135 total, 4 exonic, single-gene deletions were validated in schizophrenia cases and none in control sub

136 Furthermore, the activity of CX-6258 was validated in several Ewing sarcoma and multiple myeloma

137 It was validated in terms of specificity (methoxy/acetate signa

138 ermine antigenic changes were experimentally validated in the H1N1 antigenic variants using mass spec

139 hood Cancer Survivor Study (CCSS) cohort and validated in the St Jude Lifetime Cohort (SJLIFE) Study.

140 ain size using gene expression data and were validated in three bi-parental populations.

141 ins and their underlying signature SNVs were validated in two subsequent analyses of 6,228 and 38,248

142 DR3 levels (in plasma and PBMCs) were validated in unrelated cohorts (including long-term nonp

143 to cis-activate the TAL1 oncogene, a finding validated in vivo by chromatin immunoprecipitation seque

144 sed to identify specific therapies that were validated in vivo.

145 These results were subsequently validated in vivo.

146 SMM was defined using a validated index.

147 with (1) absence of significant symptoms by validated instrument, (2) lung function optimization/sta

148 7G database containing 44 058 experimentally validated internal mRNA m7G sites, a sequence-based high

149 M1) as a potential ZIKV receptor and further validated it through overexpression, knockout, and inhib

150 Our study aimed to validate its prognostic value in large-scale population

151 We validated its effects in an in vitro model of MI/IRI in

152 ase, Bla(Mab), using a novel assay, which is validated kinetically using the nitrocefin reporter assa

153 ts (n = 9) were used as positive controls to validate many of the neurodegeneration-related antibodie

154 By comparing these gene signatures and validated markers to HIO ECs, we find that HIO ECs grown

155 e replicated in independent datasets and, if validated, may provide useful measures of disease progre

156 dicted future progression rates with a cross-validated mean absolute error of 0.13 mm/year and to red

157 chopathologies), using a recently developed, validated method for segmenting thalamic nuclei and comp

158 The validated method was used to investigate the effects of

159 e association study (GWAS) of two previously validated metrics of cognitive resilience quantified usi

160 Cases were individuals who had a first validated MI between 2006 and 2012.

161 entists to emergently develop and clinically validate new swabs for immediate mass production by 3D p

162 case study, we discovered and experimentally validated new transcripts through the application of PRA

163 ceptibility breakpoints, the SC develops and validates new testing methods, provides guidance on how

164 anning electron microscopy of infected cells validated numerous membranous structures inside bacteria

165 etrospective cohort study assessed whether a validated objective and individual-level housing-based S

166 The method was validated on fish or swine processed food products conta

167 the earliest 80% of hospital admissions and validated on the most recent 20%.

168 ging Initiative (ADNI) dataset (n = 417) and validated on three independent cohorts: the Australian I

169 e hope that the framework will be helpful to validate other critical neuroimaging algorithms, as havi

170 We validate our approach using Argonaute eCLIP-seq and ribo

171 though future experimental work is needed to validate our model assumptions and findings.

172 selection were used to derive and internally validate our model.

173 e experiments and a clinical trial of FMT to validate our theoretical framework.

174 Our results not only validate our widely-applicable approach for inferring di

175 ed menthol to the channel and systematically validated our menthol binding models with thermodynamic

176 We validated our model against previous estimates of YF bas

177 This data further validates our animal model of GDM and is usefulness in i

178 uired for body axis and limb formation, thus validating our approach; plus, many other candidate RA t

179 ream regulator disrupts normal regeneration, validating our prediction.

180 When employed, the validated pain screen had a sensitivity of 100% (95% CI

181 Isabl supports automated deployment of user-validated pipelines across the entire data capital.

182 y of the predictive accuracy of a previously validated polygenic risk score was assessed among 4847 a

183 s due to low activity and the lack of a well-validated pooled screening toolkit.

184 f nucleic acid nanoparticles (NANPs) using a validated preclinical model, peripheral blood mononuclea

185 We validate predicted resistance mutations in CDK4, CDK6, E

186 ed at 1-kmx1-km grid cells from a previously validated prediction model.

187 In doing so, we identified and validated previously uncharacterized RBPs that modulate

188 The psychometrically validated PROs measure was reduced to a 59-item question

189 Ls) can be used to characterize, dissect and validate QTL, but the development of NILs is costly.

190 The algorithm was validated qualitatively and quantitatively using the swa

191 We could validate RBMS1, a barely described RNA-binding protein,

192 er, the lack of standardized definitions and validated reference values have hampered clinical use.

193 methodology performance needs to be further validated, results support the applicability of ATR-FTIR

194 Here, we utilized single prolonged stress, a validated rodent model of post-traumatic stress disorder

195 Quality improvement is now a validated science, and there is clear evidence that high

196 tter injury on MRI according to a previously validated scoring system.

197 y around the world, there is a need for well validated serological assays that allow the detection of

198 nical miRNAs are enriched in operons, and we validate several of these experimentally.

199 es in LRNC using a novel histopathologically validated software (vascuCAP Elucid Bioimaging, Boston,

200 rocessed using Qiime and Qiita, open-source, validated software packages.

201 y genetic and functional details required to validate speciation theory.

202 Our results also validate statistical randomness as an unexplored approac

203 s that could be considered in the absence of validated strategies.

204 The VALIDate study is the study designed to validate the IBD

205 l, this study is the first to experimentally validate sulfur acquisition systems in S. aureus and est

206 tos has the ability to place high confidence validated SV calls on a refined tumor phylogeny tree.

207 myocardial infarction (>=75 years) from the VALIDATE-SWEDEHEART trial (Bivalirudin Versus Heparin in

208 ncing, and pathway analysis on predicted and validated targets of these microRNAs implicated derepres

209 were classified into one of four previously validated temperature subphenotypes: "hyperthermic, slow

210 We use a previously-validated test of criticality: avalanche dynamics to ass

211 e trained/built using Regional and were then validated/tested on the Optimum N trial.

212 We first validate that amino acids buried within the structural c

213 ineated by active transcription start sites, validate that these boundaries are sufficient for captur

214 Using orthogonal methods we validated that PIK3CA wild-type cells adopt MAPK-depende

215 These data validate the accuracy and reproducibility of the qSVS as

216 aluate mercury (Hg) speciation in DBS and to validate the agreement between blood sources (venous vs

217 The analysis of 50 molecules was used to validate the approach in comparison to MS/MS spectra pro

218 We validate the association between low circulating SPINT1

219 The findings further validate the BPRN model as a robust preclinical experime

220 Finally, we identify and validate the casein kinase CSNK1A1 (also known as CK1alp

221 To validate the clinical relevance of these methods, we qua

222 To validate the discovery feature of LPHAMS, we characteriz

223 To validate the efficiency of this new version, analyses fo

224 hdimensional data have provided the basis to validate the existence of CCs.

225 transcript databases that have been used to validate the expression of deduced proteins through prot

226 Herein, we aim to further validate the high accuracy of this metabolomics test and

227 an cerebral organoid model of meningioma and validate the high ADC marker genes CDH2 and PTPRZ1 as po

228 The VALIDate study is the study designed to validate the IBD Disk, a visual tool easily useable in d

229 To validate the implication of these genes into A. thaliana

230 ate electrochromic devices to understand and validate the mechanism of bias-induced redox-driven colo

231 We validate the platform with a brain dialysate fluid sampl

232 he humanized mouse model, and experimentally validate the predicted function of an obesity-associated

233 Finally, we validate the proposed method through extensive simulatio

234 Results validate the PVN classification, that is, the 3 PVN dise

235 rnal quality assessment (EQA) study aimed to validate the sensitivity, specificity, and reproducibili

236 We validate the theoretical results by fitting the derived

237 new field-based infrastructure and test and validate the uniformity of HNT stress application on a s

238 Overall, our results validate the use of ECoG in clinical and basic cognitive

239 Herein, we harness MMPs 2, 8, 9, and 13 to validate the vicinal difluoro motif as a hybrid bioisost

240 We developed and psychometrically validated the AHQ as the first VH-specific, stakeholder-

241 ma cell lines cultured in hypoxic conditions validated the association of CA9 and PD-L1 expression.

242 es of Arabidopsis (Arabidopsis thaliana) and validated the biophysical and biochemical properties of

243 We validated the clinical profiles for all three CT signatu

244 First, we validated the crucial role of active STAT5 as a survival

245 e in vitro substrates of the transporter and validated the differences observed between the two varia

246 We validated the function of the top associated miRNAs by l

247 We further validated the functions of 3 new adipose IR genes by ove

248 We validated the interaction between hTR and the N (6)-meth

249 ng an integrative meta-analysis approach, we validated the link between these receptors and angiogene

250 We validated the miR-744 binding site in the 3' untranslate

251 ell kinetics data without treatment and then validated the model by showing that the inferred mechani

252 We further validated the performance of IsoFun on the genes ADAM15

253 Recently, we discovered and validated the plasmodial l-lactate transporter, PfFNT, a

254 Finally, we fine-tuned and validated the pre-trained model using 33 preterm infants

255 Characterization of this phage validated the predicted podovirus-like virion structure

256 We validated the previously developed PREDICT scoring tools

257 Our experiments validated the regulatory roles of miR-340-5p and Foxm1 i

258 ransfer of labeled bone marrow-derived cells validated the results in a murine Leishmania ear infecti

259 in reaction analyses of representative genes validated the RNA-Seq results.

260 We validated the TPW for silica columns and magnetic beads

261 Extensive characterization validates the robustness and nonperturbing nature of our

262 through a cycle of ligand-FEP calculations, validating the binding orientation of the different chem

263 The method was tested by validating the energy of the phonon modes with previous

264 Two methods for validating the multivariate analysis found that histolog

265 Se/S pouch cell with high specific capacity, validating the potential practical applications.

266 ed to a library of dipeptide analogues, thus validating the uniqueness of the molecular design which

267 on to non-iodinated poly(lactic acid) (PLA), validated their functionality as radio-opaque materials.

268 as a function of membrane coverage by ENTH, validating theoretical equations of state.

269 o the established Warburg impedance model is validated theoretically and experimentally.

270 tions play an important but separate role in validating theories.

271 We further validate these independent effects for one RA in vitro.

272 We validate these predictions for a selection of target gen

273 To validate these self-reports, medical records for all eve

274 the impact of specific peptide mutations and validated these predictions through competitive binding

275 arkinson's disease from healthy controls and validated these results in an independent cohort.

276 Notably, patient tumor data analysis validates these findings by revealing that loss of ARF s

277 To validate this acquisition, we characterized exosomes rel

278 maps as a surrogate of noble gas MRI and to validate this approach across a wide range of lung disea

279 We validate this technology with the rapid generation of th

280 We validated this finding by comparing iciHHV-6 in a furthe

281 imaging after individual ASD-gene repression validated this functional module, confirming that these

282 We validated this method by expressing the unmutated common

283 to a wild-type rabbit strain and, therefore, validated this model for conducting these experimental s

284 All four compounds were validated to cause hypocholesterolemia in Neuro-2a cells

285 RAPID was also validated to find known risk stratifying cells and featu

286 We also evaluated and validated transcriptomic differences in the primary tumo

287 cerebellar, and cortical projection neurons, validating transfer learning as a tool to adapt the mode

288 shared genetic diversity across 15 sequence-validated transmission pairs suggests that IBV experienc

289 need for reliable and noninvasive assays to validate transplant function in clinical biomanufacturin

290 With this rationale, we established a validated ultra-high-performance liquid chromatography h

291 Second, the model is biologically validated using multiple electrophysiological recordings

292 These results were further validated using publicly available datasets.

293 The method has been validated using spiked samples (tap water, blood serum,

294 Validated with both realistic synthetic data and interna

295 Sensor performance was qualitatively validated with commercially available soy allergen detec

296 Using this quantitative approach, which we validated with confocal microscopy, we significantly exp

297 s developed with synthetic DNA templates and validated with DNA from two breast cancer cell-lines and

298 evels at the group and individual level were validated with empirical impairment observed at later ti

299 The simulation framework, validated with experimental results and supported by the

300 This system was validated with the study of vanadium-based catalysts dur