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1 d the ubiquitin-dependent segregase p97/VCP (valosin-containing protein).
2 ant disorder caused by mutations in p97/VCP (valosin-containing protein).
3 olyGA aggregates, altering levels of soluble valosin-containing protein.
4 x with ubiquitinated substrates and p97/VCP (valosin-containing protein), a major driver of ER-associ
8 tudy, we show that interactions of Atx3 with valosin-containing protein and hHR23B are dynamic and mo
10 membranes, a process known to be mediated by valosin-containing protein and necessary for ER-associat
11 er functional convergence, ubiquilin 2, p62, valosin-containing protein and optineurin are all linked
13 ng SG dispersion and removal are mediated by valosin-containing protein and the autolysosomal cascade
14 ovel PTPN22 substrates (Vav, CD3epsilon, and valosin containing protein) and two known substrates of
15 very, for example, heat shock protein 70 and valosin-containing protein (area under the curve [AUC] =
17 entified the essential protein VCP/p97 (VCP, valosin-containing protein) as a novel regulator of auto
19 vers revealed a substantial reduction in the valosin-containing protein ATPase (VCP/p97) that acts to
20 h a variety of cellular activities) p97/VCP (valosin-containing protein) cause a dominantly inherited
23 toreceptors, here we show disruption of VCP (valosin-containing protein, human TER94 ortholog), a ubi
24 48 adenosine triphosphatase (ATPase) (p97 or valosin-containing protein in mammals) and its cofactor
25 unction of the functional initiator of ERAD, valosin-containing protein-interacting membrane protein
26 roteome revealed that a 9-kDa protein, small valosin-containing protein-interacting protein (SVIP), i
31 verse cellular activities), also called VCP (valosin-containing protein), is an important therapeutic
34 llowing receptor engagement, suggesting that valosin-containing protein may target the ubiquitinated
35 to the Hrd1-mediated ubiquitination and the valosin-containing protein-mediated extraction pathway.
37 FTD with mutations in progranulin (n = 36), valosin-containing protein (n = 5), charged multivesicul
39 ate proteins, such as heat shock protein 70, valosin-containing protein, or glycogen phosphorylase, m
41 he members of this family, the hexameric p97/valosin-containing protein p97/VCP, is essential for the
45 biology that has been reported to methylate valosin-containing protein/p97 (VCP) and heat shock 70-k
46 iquitination, which together with the ATPase valosin-containing protein/p97 drove ER-associated degra
52 listerin, nuclear-export mediator factor and valosin containing protein) partly due to lack of lysine
53 tion of growth factor receptors and p97 VCP (valosin-containing protein, termed Cdc48 in Saccharomyce
54 usly identified putative molecular chaperon, valosin-containing protein, undergoes tyrosine phosphory
55 acting proteins in lung AT2 cells, including valosin containing protein (VCP) and its interactors.
59 and unfolding by the essential mechanoenzyme valosin-containing protein (VCP) and on ubiquitin chain
62 ith diverse cellular activities (AAA-ATPase) valosin-containing protein (VCP) as a top stress-related
63 ns followed by proteomic analysis identified valosin-containing protein (VCP) as an Akt-binding prote
65 oupled mass spectrometry unveiled the ATPase valosin-containing protein (VCP) as novel interaction pa
76 dentified a p.R191Q amino acid change in the valosin-containing protein (VCP) gene in an Italian fami
77 genetic disorder caused by mutations in the Valosin-Containing Protein (VCP) gene with clinical feat
86 ure and in neurons that the hexameric ATPase valosin-containing protein (VCP) is recruited to ubiquit
90 ical inhibition of either the AAA ATPase p97/valosin-containing protein (VCP) or the proteasome resul
91 the membrane by the p97 ATPase [also called valosin-containing protein (VCP) or, in yeast, Cdc48].
94 uring Legionella infection, LotA counteracts valosin-containing protein (VCP) recruitment to the Legi
95 ciated with various cellular activities) p97/valosin-containing protein (VCP) subsequently dislodges
96 has been shown that blocking the binding of valosin-containing protein (VCP) to mutant huntingtin (m
99 Here, we show that mutation or inhibition of Valosin-Containing Protein (VCP), a ubiquitin-dependent
104 INK1/Parkin-mediated mitophagy by recruiting valosin-containing protein (VCP), an AAA-ATPase that fun
108 nt-negative form of the ERAD core component, valosin-containing protein (VCP), in 293A cells partiall
109 and the ubiquitin-binding protein dislocase, valosin-containing protein (VCP), may act in concert dur
110 we discovered that EPSTI1 interacts with the valosin-containing protein (VCP), resulting in the degra
111 y or by depletion or pathogenic mutations in valosin-containing protein (VCP), the human ortholog of
113 155H/R155H mutant mice are a lethal model of valosin-containing protein (VCP)-associated inclusion bo
114 y nodes-ADP-ribosylation factor 4 (ARF4) and valosin-containing protein (VCP)-controlling NIS traffic
115 mitochondrial quality control (MQC) requires valosin-containing protein (VCP)-dependent Mitofusin/Mar
118 defined reactions mediated by the AAA-ATPase valosin-containing protein (VCP)/p97 and augmented by th
119 sitional endoplasmic reticulum ATPase (TERA)/valosin-containing protein (VCP)/p97 directly binds to m
123 Binding to the AAA adenosine triphosphatase valosin-containing protein (VCP)/p97 is the only known b
129 six missense mutations in the gene encoding valosin-containing protein (VCP, a member of the AAA-ATP
132 abolished when either membrane extraction by valosin-containing protein (VCP/p97) or proteasomal degr
133 rase assay revealed that Mettl21e methylated valosin-containing protein (Vcp/p97), a key component of
134 in- and proteasome-binding factors Rad23 and valosin-containing protein (VCP/p97), findings that supp
141 We found that a p.Asp395Gly mutation in VCP (valosin-containing protein) was associated with dementia