ライフサイエンスコーパス: variation in

1 diseases, related to a heterozygous allelic variation in 1 of the 20 ribosomal protein genes of eith

2 We also analyze variation in 2329 knockout strains and establish a refer

3 ival was 50% (95% CI 48-53), but we observed variations in 3-year survival between different races in

4 Significant intraspecific variation in A is known to exist in various autotrophic

5 study by Fasolino et al. defines how genetic variation in a mouse model of type 1 diabetes mellitus (

6 Our objectives were to quantify variation in a suite of traits along a continuous elevat

7 required to define whether inter-individual variations in ABO(H) expression on platelets and/or VWF

8 A key challenge is to characterize how variation in adolescent brain organization relates to ps

9 able Ag dose thresholds across a 25,000-fold variation in affinity.

10 asses a highly heterogenous population, with variation in age, thrombosis location, and underlying me

11 We found substantial variation in all 23 root phenes measured.

12 al, domesticated and experimental phenotypic variation in all Eukaryotes-mostly animals, plants and y

13 This model accounts for variations in all the spindle traits we studied here, bo

14 ncreases in projected seasonal precipitation variation in already highly variable precipitation regim

15 Substantial variations in ambient illumination had no observable eff

16 eterogeneity, we investigated spatiotemporal variation in AMF diversity on a plot scale (10 x 10 m) i

17 (A) and CsARF14 in determining carpel number variation in an important vegetable crop - cucumber.

18 By relating individual variations in antibody response to coronavirus disease 2

19 We examined trends over time and variation in antidepressant prescribing in children and

20 to ciprofloxacin is responsive to short-term variation in antimicrobial use.

21 rations and demonstrate how this reduces the variation in aqueous-phase concentrations caused by meth

22 Geographic variation in aridity determines environmental productivi

23 However, continuous interindividual variation in ASD suggests that there is a need for a dim

24 Here, we examine variation in bark thickness across the Amazon.

25 the seasonal timing of gene expression, and variation in behaviour between them.

26 te patients within RCTs to define risk-based variation in benefit, and an "effect-modeling" approach,

27 obal priority areas that account for spatial variation in benefits and costs have yet to be identifie

28 in abundances around K, but higher temporal variation in beta within herds.

29 Whilst the majority of variation in biomarkers is at the individual rather than

30 rbivores are often linked to resource-driven variation in body condition.

31 Here, we examine age-related variation in body mass, reproductive output and survival

32 s in population density are partly driven by variation in body size and diet among organisms.

33 nnectome aging occurs on broad dimensions of variation in brain architecture.

34 the longitudinal consequences of individual variation in brain development before birth.

35 n of anticipatory responding also relates to variation in brain structure.

36 agent paralleled the gradients and regional variations in brain temperatures reported in the literat

37 th different growth conditions, we monitored variation in branch diameter in the two lavender species

38 Significant variation in break-even costs are observed across differ

39 The authors report marked variation in buffering capacity, correlated with wing si

40 he contribution of contextual effects to the variation in cALND use to that of measured variables.

41 type 1 or 2 (BRCA1/2) poses tissue-specific variations in cancer risks and primarily associate with

42 d approach can accurately reproduce seasonal variation in canopy photosynthetic potential, and sugges

43 ctivity of the stress response circuitry and variations in cardiovagal activity [normalized high freq

44 factors explained between 49.1% and 62.7% of variation in caries scores and between 50.0% and 60.5% o

45 caries scores and between 50.0% and 60.5% of variation in caries trajectories.

46 Individual variations in cellular drug uptake, metabolism, and resp

47 lone have an acceptable association with the variation in CH(4) production from beef cattle.

48 s reveal a trade-off between VTE and natural variation in chorismate metabolism explained by transcri

49 human smokers.SIGNIFICANCE STATEMENT Allelic variation in CHRNA3, which encodes the alpha3 nicotinic

50 Genetic variation in circulating RSV strains will continue to ch

51 of the root systems cannot entirely explain variations in citrate-enhanced uptake.

52 the understanding of how naturally occurring variation in clinical isolates affects transmissibility,

53 iratory support have changed but significant variations in clinical practices and outcomes between ce

54 we used fourteen polygenic scores to predict variation in cognitive ability level at age 70, and cogn

55 Spatial variations in collagen organization regulate cardiac fib

56 trength of the local optoelectronic property variations in colloidal quantum dot solar cells due to f

57 There are only small regional variations in color and spectra across the surface, whic

58 ted pain is accompanied by metacognition and variations in confidence, similar to perceptual decision

59 Quantitatively, variations in contrast-to-noise ratio (DeltaCNR) between

60 esponding wild-type (WT) gene, due to either variations in copy number or transcriptional regulation,

61 Amidst significant regional variations in COVID-19, lung transplantation (LTx) remai

62 on) were among the best predictors of global variation in CVp.

63 rhythmicity was not a significant source of variation in daily B-cell levels or any CD4+ functional

64 e speciation should initially reduce genetic variation in daughter versus parental species, a common

65 inosaurs, we infer patterns of brain-body co-variation in deep time.

66 spatial factors that could generate spatial variation in defence, highlighting the need for large-sc

67 We evaluated ecotypic variation in dehydrin gene expression in a clonal bank c

68 diversity were strongly related to regional variations in density, DO, and other variables (regressi

69 Within single axons, we find that the variation in diameter and conduction velocity correlates

70 However, how stem cells respond to dynamic variations in differentiation cues is not well character

71 There is considerable variation in disease behavior among patients infected wi

72 These features contribute toward variation in disease severity and confound genotype-to-p

73 ever, the patterns and underlying drivers of variation in dispersal across species remain unclear, pa

74 nd T. confusum) to examine how intraspecific variation in dispersal behaviour and community context i

75 ipotent progenitor cells (MPPs) show greater variation in distance from the endosteum and are more li

76 There was larger variation in divergence time estimates among datasets th

77 Overall, our findings suggest that variations in DNA methylation mediate the differential e

78 dactylus oerstedii also show between-habitat variation in dorsal body colouration.

79 nd c-Rel signaling dynamic features, such as variations in duration or time-integrated activity.

80 ado Island, Panama, we investigated temporal variation in EAGB fluxes as a function of initial EAGB (

81 drought resistance and resilience, driven by variations in eco-physiological traits.

82 es to centuries of the Anthropocene and wide variations in ecological rates of change, the theory and

83 CAR T cell infusion products contributes to variation in efficacy and toxicity after axi-cel therapy

84 criptome analysis revealed that hsdS allelic variations in Enterococcus faecalis exert significant im

85 Evolution of organ shape is fueled by variation in expression patterns of regulatory genes cau

86 swarm evolution is strongly controlled by 3D variations in fault architecture.

87 ke responses to human IgGs, there was little variation in FcgammaR-mediated responses to different su

88 ic hormones (glucocorticoids) in response to variation in food and density are one mechanism that see

89 ere is accumulating evidence that individual variation in foraging behaviour is shaped by animal pers

90 MYB10-2 are the underlying cause of natural variation in fruit skin and flesh color in octoploid str

91 complex systems would be unstable if not for variation in gamma.

92 Functional omics data reveals extensive variation in gene expression and substrate usage amongst

93 Inter-individual variation in gene expression has been shown to be herita

94 Heritable variation in gene expression is common within and betwee

95 utes to the robustness of TC through natural variation in GI and ZTL alleles found on the Cape Verde

96 Much of the seasonal variations in global [Formula: see text]O emissions can

97 Apart from slight variations in grid spacing, no difference in the spatial

98 At 366-368 DAS, CO(2) by cultivar variation in growth and biomass response among Arabica c

99 al data and lack of flexibility in capturing variation in growth rate.

100 Slight variations in growth rates were determined for both bact

101 ns in N-glycosylation in HA caused antigenic variations in H1N1 IAVs and that the sequence-based anti

102 ution to binding affinity, and that sequence variations in H2 that do not change the level of disorde

103 Within-country variations in health status are often not examined in re

104 While some geographic variations in healthcare are normal, unwarranted variati

105 role of host (and viral) genetics (including variation in HLA genes) in the immune response to corona

106 We tested the hypothesis that variation in home range size increases RABV spread and d

107 that the MOR system might underlie seasonal variation in human mood and social behavior.

108 Dozens of genes contribute to the wide variation in human pigmentation.

109 etic variation affecting normal pigmentation variation in humans.

110 We show that variations in hydrophobic residues at the active site of

111 tracellular bacterium Chlamydia trachomatis, variation in immune activation and disease presentation

112 nology seeks to identify and explain natural variation in immune function.

113 uit-fed bulbuls maintained body mass despite variation in immune function.

114 ions of genetic and environmental factors to variation in immune responses are poorly understood.

115 ackgrounds that may contribute to phenotypic variations in immune responses.

116 Our objective was to describe trends and variations in Impella use, clinical outcomes, and costs

117 Striking geographic variation in incidence and the fact that virus alone is

118 We observed geographic and temporal variations in incidence and mortality for all 5 types of

119 of humans, exhibited higher interindividual variation in infancy versus later in life.

120 re drivers of dose-dependence and individual variation in infection outcomes, we devised a mathematic

121 Long-term variations in interhemispheric surface temperature anoma

122 Variations in intervention rates, without subsequent red

123 tigate the role of climate, urbanization and variation in interventions.

124 ey component of the coagulation cascade, and variation in its circulating levels may contribute to th

125 The variation in laboratory methods between studies made com

126 Variation in leaf traits due to VPC are likely to provid

127 Mapped interisland and intraisland variation in live coral location improves our understand

128 ed way across the continent with significant variation in local expertise, cost, and utilization.

129 oking/nicotine will increase interindividual variation in lung CYP2A levels, which may impact the loc

130 We assessed here the degree to which variation in magnitude of N balance across irrigated mai

131 ng multiple maternal features when assessing variation in maternal allocation.

132 Regional variations in maternal mortality rates may relate to the

133 Although inter-individual and temporal variation in measures of oxidative balance were substant

134 Leveraging quasi-random geographic variation in media markets for 771 matched rural countie

135 h in refugee mental health has reported wide variation in mental illness prevalence data, partially a

136 vity in low-level visual areas should encode variation in mental images with less precision than seen

137 ck of possibility for standardization and to variation in methods.

138 ironment uncovers different contributions to variations in microbial responses and immune cell compos

139 This daily variation in microglial synaptic phagocytosis was abroga

140 mmation and discuss the spatial and temporal variations in microglial phenotypes that are observed un

141 nd and experimentally validated bat-specific variation in microRNAs, which may regulate bat-specific

142 The European blackcap exhibits enormous variation in migration and is renowned for research on i

143 ing that there are multiple ways to generate variation in migration.

144 e pressures along that gradient and quantify variation in migratory tendency along that gradient.

145 des a developmental framework for explaining variation in molar complexity and a means for testing de

146 hough this model provides an explanation for variation in molar proportions, what remains poorly unde

147 Here we utilized the cell-to-cell variation in morphological features of Mycobacterium tub

148 t in functionally distinct pools, displaying variations in motility as well as docking and fusion cap

149 arance (P = 4.4 x 10-2) explained 42% of the variation in MTXPG accumulation (P = 1.1 x 10-38).

150 lts of this study suggest that mutations and variations in N-glycosylation in HA caused antigenic var

151 However, there was substantial individual variation in natural history.

152 the evolutionary processes governing genetic variation in natural populations, and provides a framewo

153 is known about the nature of this individual variation in natural populations, or which components of

154 Variation in nonsteady-state efficiency greatly exceeded

155 ubstantially among climate models, enhancing variation in overall trajectories for aridity.

156 all along four continuous axes that describe variation in participants' behaviour: recording intensit

157 osts and benefits, and contribute to dynamic variation in patterns of divorce across plover breeding

158 ightly changed and FTIR spectra showed minor variation in peak intensities of oils from different MW

159 Variation in phenotypic plasticity among invader populat

160 d river discharge, explained the second-most variation in PicoP abundance (15.9%).

161 ionships of the genetic variation at OCA2 to variation in pigmentation in areas beyond Europe.

162 LTs in patients was not readily explained by variations in plasma levels of key fibrinolytic proteins

163 ng of our time-series data revealed that the variation in plasmid abundance over time explained more

164 few studies have directly assessed ancestral variation in plasticity and tracked phenotypic changes o

165 ared to low-risk environments due to genetic variation in plasticity.

166 ide with genes associated with melanin-based variation in plumage, suggesting a prominent role for se

167 ase spread by exploiting the spatio-temporal variations in policy measures across the 16 states of Ge

168 d potential to explain mechanisms underlying variation in pollinator preferences across populations,

169 adaptation can alter everything from spatial variation in population abundances to ecosystem properti

170 , depending on the model) of the genome-wide variation in population-level genetic variation from 41K

171 There was wide hospital variation in postacute care spending after cardiac surge

172 ir exceptionally large ranges, prone to high variations in precipitation.

173 This approach revealed extensive genetic variation in predator-induced plasticity in ancestral po

174 ale humpback whales were used to investigate variation in pregnancy rates through the quantification

175 Wide variation in preoperative imaging in children with suspe

176 mortality, and understand the interhospital variation in prolonged critical illness.

177 With the wide variation in quality and content of online information,

178 ges including serum sickness, batch-to-batch variation in quality and the use of animals for producti

179 and to investigate possible connections with variation in quantitative disease resistance.

180 gate the relationship between group size and variation in rainfall on dominant female fecundity, body

181 est <0.0001); however, there was significant variation in rates across hospital sites (adjusted media

182 espite evidence suggesting a large amount of variation in rates among families.

183 Interestingly, variation in recombination rate within and between popul

184 sights regarding the role of natural genetic variation in regulating gene expression and generates te

185 Genetic variation in regulatory elements can alter transcription

186 Field pea accessions showed variation in remobilization rates, with PI 125840 and PI

187 ctors represented approximately 50% of total variation in repair type, followed by patient-level (49%

188 hat determining the relative balance between variation in resource allocation and acquisition, and th

189 After accounting for spatial and temporal variation in resources, we show that the apparent positi

190 -hydrogels exhibit volumetric and dielectric variations in response to environmental glucose concentr

191 species (assigned to 18 FG) reveals regional variation in responses to both long-term (2006-2016) cha

192 Spatial predictions demonstrated variation in responses to extreme weather across species

193 eaths (for example 48.7%), but there is wide variation in risk across communities.

194 Variation in risk factors across host-disease pairs sugg

195 ifically designed to overcome the inevitable variations in sample quality resulting from uncontrollab

196 tion and more recently for studying 'wanted' variation in scRNA-seq data.

197 c basis and climatic associations of natural variation in seed chilling responses and associated life

198 m phenotype need not directly translate into variation in selection gradients, because their impact c

199 intertwined with ecological dynamics and (2) variation in selection that prevents traits from becomin

200 asis for further investigation into temporal variations in self-harm among asylum seekers, which may

201 syndrome coronavirus 2 requires quantifying variations in sensitivity with disease severity and over

202 show that eFC is systematically modulated by variation in sensory input.

203 ferences in seroprevalence, with significant variation in seropositivity over time and among roosts.

204 The variation in several metabolite pools such as malate, fu

205 Why is there such prominent variation in sexual receptivity length among primate spe

206 ological mechanisms that underlie individual variation in shift work tolerance.

207 gs, yet little is known about facility-level variation in short-term safety outcomes.

208 nge in bulk solidification conditions on the variation in single crystal mosaicity was investigated.

209 ce modified silica nanoparticles (SNPs) with variations in size and porosity (Stober SNPs 46 +/- 4.9

210 iscrimination performance obtained for large variations in size was no lower than that obtained for s

211 was no lower than that obtained for smaller variations in size.

212 olution, development, and genetics of chiral variation in snails, and place it in context with other

213 However, the degree to which spatial variation in soil microbial communities modulates plant

214 Systematic variations in solvent composition and temperatures in AS

215 robust guidance, there remains a significant variation in some elements of best practice for RDS mana

216 We then test whether life history explains variation in species' niches and niche-distribution mism

217 To resolve spatial and seasonal variation in species' response, we use a unique dataset

218 n CFN and variations in the core genome, but variations in specific regions of the nod locus, as well

219 This study evaluates the variation in spending by the highest-quality hospitals p

220 urgical episode spending, but the sources of variation in spending have not been explored.

221 There was also a 10-fold variation in stability depending on the nature of the ox

222 We found that strain-level variation in staphylococcal isolates governs the interac

223 ommunity richness both explained significant variation in Streptomyces beta diversity.

224 eta-analytic pooling was not possible due to variations in study designs; therefore, studies were sum

225 SNPs explained 4.6% [CI-95: 2.9-6.3%] of the variation in suicide attempt.

226 ential for profound adverse events and large variations in survival outcome.

227 response to the warming treatment, tracking variation in T(air) .

228 evidence that genetically influenced common variation in telomere length impacts hematologic traits

229 dependent on solution conditions, even small variations in temperature or pH can have a pronounced ef

230 s and water, high pH and exposure to extreme variations in temperature, humidity and irradiation.

231 y across the United States, and center-level variation in testing, clinical practice, and policies, w

232 udy, we investigated how natural interstrain variation in the amino acid sequence of gO influences th

233 average final complexoform assembly and the variation in the assembly structure.

234 mined both mitochondrial and nuclear genomic variation in the collared lemming (Dicrostonyx torquatus

235 sess the distribution and the homogeneity in variation in the composition of macroinvertebrate assemb

236 We found substantial variation in the degree of placentation among natural po

237 -glucose environment, and we observe natural variation in the frequency of the two states across wild

238 that performance was weakly associated with variation in the gut microbiome.

239 we jointly analyse genetic and morphometric variation in the house mice (Mus musculus domesticus) fr

240 There is considerable variation in the magnitude of weight regain after RYGB,

241 eatment effect (HTE) refers to the nonrandom variation in the magnitude or direction of a treatment e

242 ns in the fitness function, causing temporal variation in the magnitude, but not the direction of sel

243 The goal of this work was to assess variation in the MAMP response in sorghum, to map loci a

244 difference was linked to population-specific variation in the maternal provisioning of lipids to offs

245 Variation in the outcome of tuberculosis infection and d

246 A are perceived, defined, and measured, with variation in the perceived importance of REA in both cli

247 Given the significant hospital variation in the percentage of failure to cure, improvem

248 However, we found a large variation in the performance of fenestrations made with

249 post-stroke aphasia demonstrate considerable variation in the presentation of symptoms.

250 A large variation in the proportion of shared zOTUs was observed

251 mate change has been hampered by substantial variation in the rates and even directions of response t

252 wing hepatopancreatic procedures with a wide variation in the rates of TO among hospitals.

253 text-dependence is expected to generate more variation in the sign and magnitude of selection on soci

254 Variation in the survival of THR implants has been obser

255 Variation in the terminal psi angles of the NPNA beta-tu

256 In this study, we used the variation in the timing of implantation from the first t

257 ect herbivores to light-environment-mediated variation in the traits of their host plants is central

258 However, there is variation in the ultrasound diagnostic thresholds used t

259 We find that variations in the common core and emergence of hypervari

260 is coated in cuticular hydrocarbons (CHCs); variations in the composition of this layer affect a ran

261 ound for genetic association between CFN and variations in the core genome, but variations in specifi

262 c assembly graphs that is based on analyzing variations in the coverage depth between viruses and bac

263 ulated temperature can be explained with the variations in the daily temperature patterns in 2013 and

264 This wide range arises from variations in the efficiency of iron retention in the up

265 particular area of focus is the link between variations in the El Nino-Southern Oscillation (ENSO) an

266 atures for axon recognition and is robust to variations in the extent of ON tissue damage, image qual

267 nside a thin soap membrane, smooth thickness variations in the film act as a correlated disordered po

268 whether the described behavior is robust to variations in the given setup.

269 of shell forms and highlights how parametric variations in the growth process result in morphological

270 e used a metapopulation framework to explain variations in the incidence of infections caused by seve

271 tion of 300-1000 mg peanut protein, although variations in the kinetics of passage were observed betw

272 ysis of DNA from 79 subjects showed sequence variations in the latent protein, LMP1, which alters NK

273 environments of the framework metals lead to variations in the linker stacking geometries and optical

274 niform magnetic domain that is attributed to variations in the magnetization state across the phase b

275 oring is an efficient tool to study temporal variations in the occurrence and behaviour of vocalizing

276 n (CSP) variants of P. vivax, besides having variations in the protein repetitive portion, can differ

277 Variations in the TLR10/1/6 locus appear to be linked wi

278 es among cultivars resulted in up to 15-fold variations in the total phenol concentration.

279 nge and how they relate to local temperature variation in their habitats is crucial to determining vu

280 mercial lines and showed substantial natural variation in their responses.

281 were categorized into 3 groups according to variations in their median LOS as follows: major decreas

282 Variation in these parameters, such as the rate of tumou

283 about the genetic architecture of phenotypic variation in these populations.

284 Natural variation in these processes produces the diversity of s

285 s to expression of the locus and suggest how variation in these SEs may contribute to human disease a

286 What accounts for the variation in this critical social cue across primate spe

287 nguage abilities; however, it is unclear how variation in this input relates to preverbal brain circu

288 We examine variation in this specific gene expression pattern acros

289 pathway that activates mTORC1 in response to variations in threonine (Thr) levels via mitochondrial t

290 Despite marked variation in tissue architecture and regenerative demand

291 and abiotic factors resulted in significant variation in total plant mass, diaspore mass, mass alloc

292 s needed to repress trichome fate, underlies variation in trichome patterns between all Antirrhinum s

293 We investigated variation in two behaviours at three different temperatu

294 epal, potential geographic and socioeconomic variation in underweight and overweight and/or obesity p

295 odels were used to characterize county-level variation in use of surgery and CSS.

296 We did not account for within-country variation in vaccine coverage, and the optimisation was

297 s expected to trigger an increasing trend of variation in vegetation phenology.

298 il the ecological mechanisms behind temporal variation in vertebrate responses to tree diversity and

299 For chemicals which showed high variation in water bodies, DGT provided a better integra

300 f WUE relate, and how well they each capture variation in WUE with soil moisture availability.