ライフサイエンスコーパス: vascular lesion

1 ion of monocytes and T cells around sites of vascular lesion.

2 fied areas or osteoblast-like cells in human vascular lesions.

3 immunohistochemistry for evidence of complex vascular lesions.

4 rophile infiltrates, and Shiga toxin-induced vascular lesions.

5 the pulmonary arterioles by the formation of vascular lesions.

6 tively active Notch1 induced similar hepatic vascular lesions.

7 hotothermolysis" is widely used for treating vascular lesions.

8 (BM-derived) immune cells that migrate into vascular lesions.

9 retinopathy and contribute to the resultant vascular lesions.

10 sappearance, a desired endpoint for treating vascular lesions.

11 Animals in group 2 never developed vascular lesions.

12 hemangiomas, and may be useful for cutaneous vascular lesions.

13 n in nude mice, form lumen-obliterating lung vascular lesions.

14 oss of PPARgamma expression in their complex vascular lesions.

15 c ring assay and after injection into murine vascular lesions.

16 oup 5 recipients accepted allografts without vascular lesions.

17 to protect against diabetes-induced retinal vascular lesions.

18 cells (VSMCs) contribute to the formation of vascular lesions.

19 -recognized component of the pathogenesis of vascular lesions.

20 onship between elevated PAI-1 expression and vascular lesions.

21 the small bowel angiodysplasias and abnormal vascular lesions.

22 VSM) mitogen that is expressed in developing vascular lesions.

23 ssel wall or be incorporated into developing vascular lesions.

24 olic regulatory genes in the pathogenesis of vascular lesions.

25 omoted lung cell apoptosis and resolution of vascular lesions.

26 ent also reduced the incidence and extent of vascular lesions.

27 erial extravasation or posttraumatic splenic vascular lesions.

28 the Ink CKI, p16(Ink4), is not expressed in vascular lesions.

29 rdinating the cellular events that result in vascular lesions.

30 ces the formation of thrombus and neointimal vascular lesions.

31 completely suppressed enhanced formation of vascular lesions.

32 f vascular hypertrophy and the generation of vascular lesions.

33 herapeutic tool in the treatment of SMC-rich vascular lesions.

34 roteins expressed by endothelium at sites of vascular lesions.

35 atherosclerosis and have fewer monocytes in vascular lesions.

36 ting mechanisms linked to the development of vascular lesions.

37 oses an individual to develop HHT-associated vascular lesions.

38 agement should emphasize scoring of specific vascular lesions.

39 es induced apoptosis and acute regression of vascular lesions.

40 withdrawal is associated with regression of vascular lesions.

41 et cell sensitization and the development of vascular lesions.

42 creased left ventricular performance without vascular lesions.

43 opment of atherosclerotic and injury-induced vascular lesions.

44 ion of a disease-prone cell type within some vascular lesions.

45 to accumulate preferentially within areas of vascular lesions.

46 and lymph node lesions; germ cell tumors and vascular lesions.

47 enchymal-like cells in obstructive pulmonary vascular lesions.

48 ould be monitored for the development of new vascular lesions.

49 g occurred in subjects both with and without vascular lesions.

50 d PCR was performed only in the samples from vascular lesions.

51 atofibroma; melanoma; melanocytic nevus; and vascular lesions.

52 oles in the inflammatory cell recruitment to vascular lesions.

53 t may be relevant to the pathogenesis of HHT vascular lesions.

54 ion diet resulted in reduced IK17 binding to vascular lesions.

55 t for mediating immune cell infiltration and vascular lesions.

56 tients, Th1 and Th17 cells co-existed in the vascular lesions.

57 endothelial cells in occlusive and plexiform vascular lesions.

58 h17 but not the Th1 arm in the blood and the vascular lesions.

59 appearance of skeletal elements in calcified vascular lesions.

60 al target for drug development against these vascular lesions.

61 Seventy consecutive patients provided a vascular lesion, a blood sample, and 36 subgingival samp

62 ificant Alzheimer disease neuropathology and vascular lesions, a cognitively and physically intact ce

63 Hyalinosis is a vascular lesion affecting the renal vasculature and cont

64 Cerebral cavernous malformations (CCMs) are vascular lesions affecting the central nervous system.

65 uma, haemodynamic instability resulting from vascular lesions and active bleeding is the main cause o

66 KS-derived spindle cells induce vascular lesions and display enhanced vascular permeabil

67 ere receiving sirolimus had no recurrence of vascular lesions and had decreased vascular proliferatio

68 These vascular lesions and other classic histologic features w

69 hydes may exert potent biological effects in vascular lesions and other sites of inflammation.

70 ed the importance of comparing patients with vascular lesions and patients with neurodegenerative dis

71 n pancreas transplants with specification of vascular lesions and prospects for defining a vasculariz

72 found that TopBP1 expression was reduced in vascular lesions and pulmonary endothelial cells isolate

73 asL) expression has been detected in chronic vascular lesions, and Fas-mediated apoptosis of vascular

74 NFT deposition, vascular lesions, and high NPC scorewere associated with

75 of neurofibrillary tangles, amyloid plaques, vascular lesions, and Lewy bodies.

76 microbleeds, coexistent ischemia, associated vascular lesions, and markers of hemorrhage expansion is

77 data from primary cells isolated from human vascular lesions, and we found that glucose sensitivity

78 matory chorioretinal or inflammatory retinal vascular lesions, anterior chamber cell grade, vitreous

79 Before intramural coronary vascular lesions appeared at week 4 of ALDOST, we found

80 re of the antiphospholipid syndrome, chronic vascular lesions are common, particularly in patients wi

81 used and that archaic terms are avoided when vascular lesions are described.

82 Because the vascular lesions are homogeneously distributed throughou

83 tion (TAVI), but the etiology and effects on vascular lesions are largely unknown.

84 IE2-dependent mechanisms triggering enlarged vascular lesions are not well understood.

85 Eventually, the vascular lesions are occupied by self-renewing T cells t

86 Intravitreal hAS0326 inhibited retinal vascular lesion area and neovessel volume in a laser-ind

87 The vascular lesions associated with autoimmune small-vessel

88 an MADH4 mutation should be screened for the vascular lesions associated with hereditary haemorrhagic

89 st that the mTORC pathway is involved in the vascular lesions associated with the antiphospholipid sy

90 From P15 onward, Vldlr(-/-) retinas develop vascular lesions associated with the local upregulation

91 entification and treatment of the underlying vascular lesions at an early stage can also prevent subs

92 rsor IRMA lesions were intraretinal tortuous vascular lesions at baseline and that they developed int

93 hrombin mediates the formation of neointimal vascular lesions at sites of mechanical vascular injury

94 neurofibrillary tangle (NFT) pathology, and vascular lesion burden were determined.

95 f smooth muscle cells is a common feature of vascular lesions but its pathophysiological significance

96 s well established in both benign tumors and vascular lesions, but has only limited applicability for

97 rime monocytes for enhanced recruitment into vascular lesions by increasing monocytes' responsiveness

98 ne may play an important role in stabilizing vascular lesions by promoting SMC collagen synthesis.

99 We show that blocking formation of these vascular lesions by two independent mechanisms, tamoxife

100 ontribute to the pathogenesis of Stx-induced vascular lesions by up-regulating toxin receptor express

101 c differentiation of smooth muscle cells and vascular lesion calcification, and also support a role f

102 Cerebral cavernous malformations (CCM) are vascular lesions causing seizures and stroke.

103 Our data suggest that in the vascular lesions characteristic for GCA, a subset of mac

104 connexin 43 downregulation promotes retinal vascular lesions characteristic of diabetic retinopathy

105 ositive capillary cells at 6 to 8 months and vascular lesions characteristic of retinopathy at 18 mon

106 The etiology and pathogenesis of the vascular lesions characterizing primary pulmonary hypert

107 Immunohistochemistry was used to investigate vascular lesion composition and the different layers of

108 riovenous malformations (AVMs) are high-flow vascular lesions consisting of abnormal shunts between a

109 Venous malformations are low-flow vascular lesions consisting of disorganized thin-walled

110 percortisolemia induces diabetes or diabetic vascular lesions contribute to mania, an overlapping fun

111 RPE and vascular lesions develop secondarily with increasing pen

112 Vascular lesions developed randomly without regard for v

113 l-animal model in which diabetes accelerates vascular lesion development.

114 ecular link between diabetes and accelerated vascular lesion development.

115 ironment has been proposed to exist within a vascular lesion due to intimal or medial cell proliferat

116 kidney pathology primarily characterized by vascular lesions (e.g., thrombotic microangiopathy and v

117 to test the hypothesis that microscopic IPAH vascular lesions express unique molecular profiles, whic

118 Most orbital vascular lesions express VEGF receptors, which may sugge

119 Despite more occlusive vascular lesions, fasudil also markedly reduced right ve

120 plications of overzealous needling of such a vascular lesion for histopathological diagnosis as in ou

121 avernous malformations (CCMs) in which focal vascular lesions form throughout the central nervous sys

122 Pyogenic granulomas, acquired vascular lesions, form on the ocular or palpebral surfac

123 mmation has been suggested to play a role in vascular lesion formation after angioplasty.

124 Ionizing radiation has been shown to reduce vascular lesion formation after balloon overstretch inju

125 It is postulated that vascular lesion formation and remodeling involves a bala

126 we show that Id3a protein is induced during vascular lesion formation and that Id3a expression peaks

127 myofibroblasts contribute to the process of vascular lesion formation by proliferating, synthesizing

128 pled receptors (GPRCs) and may contribute to vascular lesion formation by stimulating proliferation o

129 (KO) mice and showed that the A2bAR prevents vascular lesion formation in an injury model that resemb

130 ents in the response to injury that typifies vascular lesion formation in atherosclerosis and resteno

131 been implicated as an important mediator of vascular lesion formation in atherosclerosis and resteno

132 ory properties, in inhibiting injury-induced vascular lesion formation in both naive and immunologica

133 Here, we show that during vascular lesion formation in rats, an alternative isofor

134 by thrombin in vitro and is associated with vascular lesion formation in vivo.

135 e of GATA-6 downregulation in injury-induced vascular lesion formation, adenoviral vectors were used

136 decrease the extent of granulation tissue or vascular lesion formation, and that the vascularization

137 termine whether endothelial Akt could affect vascular lesion formation, mutant mice with a constituti

138 isoform that acts to limit SMC growth during vascular lesion formation, providing the first evidence

139 ing DNA replication, VSMC proliferation, and vascular lesion formation, suggesting that PGC-1beta may

140 Given that Ang II promotes vascular lesion formation, we examined whether this matr

141 expression in vivo and in protecting against vascular lesion formation.

142 d in NAD(P)H oxidase-dependent manner during vascular lesion formation.

143 th muscle cells (SMCs) and may contribute to vascular lesion formation.

144 a novel and critical mediator that inhibits vascular lesion formation.

145 SMCs) is key to understanding and modulating vascular lesion formation.

146 ted Ang II-responsive genes that may mediate vascular lesion formation.

147 angioplasty might have an important role in vascular lesion formation.

148 udies to dissect the contributions of ROS to vascular lesion formation.

149 effect on the development and progression of vascular lesion formation.

150 harmacological PPARgamma agonists attenuates vascular lesion formation.

151 ate VSMC growth and matrix production during vascular lesion formation.

152 to vascular injury plays a critical role in vascular lesion formation.

153 induced VSMC migration, an important step in vascular lesion formation.

154 cated in pathological cardiac remodeling and vascular lesion formation.

155 luent density were surgically implanted, and vascular lesion formations at distal graft-vessel anasto

156 both Ang II and macrophages was observed in vascular lesions from all 5 monkeys after regression of

157 nd (TRAIL) immunoreactivity within pulmonary vascular lesions from patients with idiopathic PAH and a

158 -specific responses in the retina, including vascular lesions, glial dysfunction, and neurodegenerati

159 specific responses in the retina, leading to vascular lesions, glial dysfunction, and neurodegenerati

160 cells (EC) and fibroblasts and its effect on vascular lesion growth.

161 I vessels versus larger vessels: the type I vascular lesion has a large component of proliferating m

162 nd ECs is a potential treatment strategy for vascular lesions having a fibrous component.

163 years, which was clinically identified as a vascular lesion in the area of calcaneus and talus.

164 extravasation in seven patients and splenic vascular lesions in 19 patients.

165 tension (PH) in 99 (63%) patients and peptic/vascular lesions in 57 (37%).

166 e prognostic significance of common specific vascular lesions in acute allograft rejection.

167 nderstand the pathophysiology underlying the vascular lesions in CCM, it is critical to develop a rep

168 tions to the use of the pulsed dye laser for vascular lesions in children are discussed.

169 utations in endothelial cells (EC) result in vascular lesions in CM-AVM is unknown.

170 s may provide a useful approach for reducing vascular lesions in diabetic retinopathy.

171 critical role in the development of retinal vascular lesions in early DR.

172 etic peptides recognize both parenchymal and vascular lesions in FBD patients.

173 site Tissue Allograft, but the role of early vascular lesions in graft rejection warrants additional

174 t may be a novel target for the treatment of vascular lesions in HHT2.

175 Studies of vascular lesions in humans and animal models documented

176 cells, cluster in the vicinity of pulmonary vascular lesions in humans and contribute to PH developm

177 results support a role for various placental vascular lesions in medically indicated and spontaneous

178 ith the constitutively active Rac1QL induced vascular lesions in mice that were remarkably similar to

179 iates with lower cognitive ability and brain vascular lesions in older age, independently of early-li

180 MCs are a key regulator of vascular lesions in patients with TAK and may represent

181 nt with a role in the formation of pulmonary vascular lesions in PPH, and reduced BMPR-II expression

182 olerance induction and prevention of chronic vascular lesions in recipients of simultaneous heart and

183 The reduction of vascular lesions in resveratrol-treated Vldlr(-/-) mice

184 The discovery of complex vascular lesions in SHIV-nef- but not SIV-infected anima

185 (PAH), which is characterized by obstructive vascular lesions in small arteries.

186 direct pressure gradient measurements across vascular lesions in swine.

187 Most vascular lesions in TAK can be effectively, safely, and

188 We observed vascular lesions in the brains of 55% of the double-muta

189 signaling pathway, cause blood and lymphatic vascular lesions in the human autosomal dominant vascula

190 These mice developed age-dependent vascular lesions in the skin, extremities, oral cavity a

191 It is suggested that the antral vascular lesions in these patients may represent a compo

192 chanisms may contribute to acute and chronic vascular lesions in transplants.

193 vesicles, as has been described in calcified vascular lesions in vivo as well as in bone and teeth.

194 mediated tissue damage is the development of vascular lesions in which endothelial cells are swollen

195 ically abnormal smooth muscle cells in early vascular lesions included elastin, among other matrix el

196 hrix jacchus) develop characteristic retinal vascular lesions including macular edema (ME), a leading

197 s and gastrointestinal bleeding secondary to vascular lesions, including angiodysplasias.

198 Typical vascular lesions, including telangiectasia, were demonst

199 Tissue factor, which is expressed in vascular lesions, increases thrombin production, blood c

200 derived cells from p27(-/-) mice repopulated vascular lesions induced by mechanical injury in p27(+/+

201 ons, the majority are autopsy series and the vascular lesion involves the bronchial arteries.

202 To test the hypothesis that the KD vascular lesion is an activated T lymphocyte-dependent p

203 rotid Doppler followed by cMRA if a cervical vascular lesion is suspected.

204 morrhagic telangiectasia (HHT), the hallmark vascular lesion is termed an arteriovenous malformation,

205 ease of o,o'-dityrosine in LDL isolated from vascular lesions is consistent with the hypothesis that

206 Medical therapy for vascular lesions is in its infancy but shows promise.

207 A hallmark of vascular lesions is the phenotypic modulation of vascula

208 nas were analyzed for vascular permeability, vascular lesions, leukostasis, morphologic changes of mi

209 Although hemangiomas are well-known vascular lesions, little is known about the mechanisms t

210 ibutes to the development and progression of vascular lesions, little is known regarding the molecula

211 ial cavernous hemangiomas (ECHs) are complex vascular lesions mainly found in the spine and cavernous

212 h has shown that the extent and depth of the vascular lesion may be contributing factors in promoting

213 ragility, leading to the suggestion that the vascular lesion may be of a secondary nature.

214 proved recognition of these often-undetected vascular lesions may be important for identification of

215 Stx-induced intestinal, renal, and CNS vascular lesions may involve a localized production of p

216 NHL and benign cutaneous vascular lesions not associated with AIDS were used as n

217 y be the superior predictive factors for the vascular lesion of CAD and represent novel therapeutic t

218 The vascular lesion of CR, transplant vascular sclerosis (TV

219 Vascular lesions of aortic isografts and allografts were

220 ect and display different characteristics of vascular lesions of clinical and/or research interest.

221 of oxidative stress is known to inhibit the vascular lesions of early diabetic retinopathy, and we i

222 suppressing proinflammatory cytokines in the vascular lesions of GCA.

223 Direct assessment of the vascular lesions of model animals in vivo is important f

224 xamined for the development of early retinal vascular lesions of NPDR and compared to littermates at

225 inflammatory cell infiltration in pulmonary vascular lesions of patients with idiopathic pulmonary a

226 ytes, and dendritic cells are present in the vascular lesions of PH, whether in idiopathic pulmonary

227 Finally, aortic vascular lesions of the aspirin-treated animals showed 5

228 Cerebral cavernous malformations (CCMs) are vascular lesions of the central nervous system appearing

229 CCMs) are sporadically acquired or inherited vascular lesions of the central nervous system consistin

230 OCTA was able to non-invasively assess vascular lesions of the choroid/retina in patients with

231 Vascular lesions of the orbit, although not malignant, c

232 and their subtypes are expressed on selected vascular lesions of the orbit.

233 nd of the alpha1-adrenergic receptor (AR) on vascular lesions of the retinopathy in experimentally di

234 In cardiac allografts, mild vascular lesions of varying NI were detectable by day 30

235 TAVI was performed in 15 of 18 patients with vascular lesions, of whom 11 agreed to a second capsule

236 In patients who require transplantation, vascular lesions often recur.

237 y 2015) who developed a new-onset, expanding vascular lesion on his right leg.

238 uorescein angiography, and lack of choroidal vascular lesion on indocyanine green angiography.

239 sequencing of the well-demarcated, blanching vascular lesion on the lateral right shin revealed a som

240 Distinctive vascular lesions on chest radiographs and CT scans in Ei

241 Characterization of vascular lesions on the basis of visual estimation of pe

242 (P = 0.0002) and the development of punctate vascular lesions on the colonic surface, which correspon

243 lesions that were overlooked (50%), 2 - with vascular lesions only, which were either overlooked, mis

244 ues harboring only dysplasia with or without vascular lesions onto nude mice was able to yield HCCs c

245 sheath, epidermal inclusion cysts, lipomas, vascular lesions, peripheral-nerve tumours, skin cancers

246 In response to agonists produced at vascular lesions, platelets release a host of components

247 These vascular lesions potentially mark cerebrovascular frailt

248 mutant cells form enlarged lumens mimicking vascular lesions present in VM patients, independently o

249 ion of 3-chlorotyrosine in HDL isolated from vascular lesions raises the possibility that MPO, by vir

250 tion of 3-nitrotyrosine in LDL isolated from vascular lesions raises the possibility that NO, by virt

251 ts against inflammaging, limiting kidney and vascular lesions related to aging.

252 sters recapitulate histopathologic pulmonary vascular lesions reported in patients with COVID-19.

253 etinal stages long before the development of vascular lesions representing the classic hallmark of di

254 Intraosseous vascular lesions resemble orbital cavernous venous malfo

255 Vascular lesions resulting from injury are characterized

256 ignificant changes in cortical structure, or vascular lesions several months after recovery.

257 cant correlation between acute rejection and vascular lesion severity in the WF-LEW combination (r=0.

258 g factor in multiple vascular disorders, and vascular lesion severity is tempered by enhanced endothe

259 RNA sequencing of the vascular lesions shows abundant expression of molecules

260 diagnose and assess the risk of intracranial vascular lesions such as atherosclerosis, aneurysms, dis

261 pathogenic similarities between TV and other vascular lesions such as atherosclerosis.

262 Pelvic vascular lesions such as pseudoaneurysms and arterioveno

263 Vascular lesions such as venopathy and--to a lesser exte

264 l oxidation products known to be enriched in vascular lesions, such as 1-hexadecanoyl-2-oxovalaryl-sn

265 share pathological hallmarks with peripheral vascular lesions, such as increased inflammation and oxi

266 Successful treatment of pediatric vascular lesions, such as port-wine stains requiring mic

267 of selected CD4+ T cell specificities in the vascular lesions support the model that giant cell arter

268 tx2e in their blood developed more-extensive vascular lesions than pigs without detectable Stx2e in t

269 us malformations of the brain are congenital vascular lesions that affect 0.01-0.50% of the populatio

270 However, biopsy specimens showed that vascular lesions that can be associated with humoral rej

271 pth the influence of diabetes on the various vascular lesions that cause brain ischemia.

272 vasculature along with formation of multiple vascular lesions that closely resemble human cavernomas

273 in the remodeling of extracellular matrix in vascular lesions that could lead to plaque weakening and

274 The vascular lesions that develop consist of direct arteriov

275 es characterized by complex, lumen-occluding vascular lesions that develop in genetically susceptible

276 ple enchondromas and tested a range of other vascular lesions that enter into the differential diagno

277 vides insight into the nature of the retinal vascular lesions that likely represent a clinical correl

278 d to cerebral cavernous malformations (CCM), vascular lesions that most frequently occur in the brain

279 ovenous malformations (BAVMs) are congenital vascular lesions that often present as cerebral hemorrha

280 Pseudoaneurysms are common vascular lesions that result as a complication of endova

281 iven that mutations were absent in 154 other vascular lesions, the mutation seems to be highly specif

282 iltration of the graft or the development of vascular lesions typical of chronic rejection.

283 at develops in some diabetics was due to the vascular lesions used to characterize the disease.

284 seven patients) and a posttraumatic splenic vascular lesion was 83% (10 of 12 patients) sensitive on

285 the 22 patients with contained injuries, the vascular lesion was visualized only at the arterial phas

286 The sensitivity of CT for detecting vascular lesions was 100%, specificity was 89% (8 of 9),

287 Furthermore, macrophage recruitment to vascular lesions was significantly reduced in EBP50 knoc

288 The typologies of vascular lesion were: pseudoaneurysm 57%, bleeding with

289 to inhibit calcification in kl/kl mice, and vascular lesions were characterized in the kidney.

290 In retrospect, none of these vascular lesions were evident in the initial CTA and DSA

291 Three previously undescribed vascular lesions were identified histologically in Eisen

292 owever, the non-AIDS-related NHLs and benign vascular lesions were negative.

293 5.0%] male) underwent capsule endoscopy, and vascular lesions were present in 18 patients (75.0%).

294 n miR-144 knockout mice by high fat diet and vascular lesions were quantified by Oil Red-O staining o

295 st this hypothesis, plexiform and concentric vascular lesions were serially microdissected from lung

296 will contribute to our understanding of this vascular lesion, which remains a leading cause of morbid

297 patients with severe PH demonstrates complex vascular lesions, which contain inflammatory cells, we w

298 eserves elastin components of ECM within the vascular lesions, which, at least in part, is modulated

299 sociated with retinal vascular inflammation, vascular lesions with increased leukocyte adhesion and c

300 Cerebral cavernous malformations (CCMs) are vascular lesions within the central nervous system that