ライフサイエンスコーパス: vascular network

1 typic endothelial cell specialization of the vascular network.

2 ethod for quantifying FAZ at the superficial vascular network.

3 mplexes is transmitted into the intraretinal vascular network.

4 ed MR imaged functional changes in the tumor vascular network.

5 changing the numerical representation of the vascular network.

6 4679), suggesting a highly organized hepatic vascular network.

7 eling of primary blood vessels into a mature vascular network.

8 twork and lymph through a low-pressure, open vascular network.

9 ntly by providing circulating minerals and a vascular network.

10 that these cells followed a pre-established vascular network.

11 S1P receptor-1 (S1P1) stabilizes the primary vascular network.

12 se and rapidly reassembled into a functional vascular network.

13 tracellular matrix components and the intact vascular network.

14 ivert blood flow to the developing implanted vascular network.

15 is is critical in the expansion of the tumor vascular network.

16 eas as a single organ through the integrated vascular network.

17 nd a transparent, macroscopic extracorporeal vascular network.

18 tissue and participate in regeneration of a vascular network.

19 ering requires formation of a de novo stable vascular network.

20 he timely formation of a well differentiated vascular network.

21 d in culture, allantoides assemble a primary vascular network.

22 ensures the formation of a mature and stable vascular network.

23 which shares similarities with formation of vascular network.

24 h using a one-dimensional model of the human vascular network.

25 growth factor A (VEGFA) to define a resident vascular network.

26 d remodel to ultimately build a hierarchical vascular network.

27 ional responses that form a highly efficient vascular network.

28 s required for the formation of a functional vascular network.

29 blood flow for the formation of a functional vascular network.

30 hormone-producing cell types and an invading vascular network.

31 pectives to engineer the optimal, functional vascular network.

32 AVM, since it can clearly depict the related vascular networks.

33 eptor 2 (VEGF-R2) expression in peri-infarct vascular networks.

34 nificantly decreased formation of functional vascular networks.

35 ricyte association was improved, with larger vascular networks.

36 restricted vascular leakage, and stabilized vascular networks.

37 tem enabling brain endothelial cells to form vascular networks.

38 ascular front of developing and pathological vascular networks.

39 migrated through areas devoid of established vascular networks.

40 low-dependent clinical assays and biomimetic vascular networks.

41 underlies the formation of blood vessels and vascular networks.

42 lony-forming cells (ECFCs) to form efficient vascular networks.

43 ux, perfusion, and also development of newer vascular networks.

44 flecting very narrow vessels forming complex vascular networks.

45 d grafts showed preserved islets and intense vascular networks.

46 genesis is a key process in the formation of vascular networks.

47 lar plexuses are remodeled into hierarchical vascular networks.

48 iour of endothelial cells (ECs) as they form vascular networks.

49 eep (0.616 mm(2) vs. 0.372 mm(2); P < 0.001) vascular networks.

50 and are required for the formation of stable vascular networks.

51 cess by which new vessels form from existing vascular networks.

52 y potentially result in in vivo formation of vascular networks.

53 lar density in both the superficial and deep vascular networks.

54 scent endothelial cells to form a functional vascular network, a process termed 'angiogenesis'.

55 We characterized the organization of the vascular network across brain regions, highlighting loca

56 regulator in the maturation of the lymphatic vascular network affecting valve development and lymphat

57 The plant vascular network also transports water, photosynthates,

58 Here we show that implanted vascular networks anastomose with host vessels through a

59 Instead, low-dose TNFalpha stabilizes the vascular network and improves vessel perfusion.

60 would remodel both the VEGFR3(+) pericystic vascular network and larger renal lymphatics that may al

61 MLL1 is overexpressed along the line of vascular network and localized adjacent to endothelial c

62 nsport blood through a high-pressure, closed vascular network and lymph through a low-pressure, open

63 ion to enable user-defined geometries of the vascular network and microfluidic perfusion to control m

64 ial progenitors in stabilizing nascent brain vascular network and provide novel insights into the mol

65 that this network is separate from the blood vascular network and that it drains interstitial fluid f

66 Acutely after TBI there is a reduction in vascular network and vascular complexity that are exacer

67 Conditioned media promoted equivalent vascular networks and CAC recruitment with superior effe

68 ]) can bias hematocrit distribution in tumor vascular networks and drive heterogeneous oxygenation of

69 ces in bioprinting solid organs with complex vascular networks and functioning microstructures, advan

70 Myc-deficient mice fail to develop normal vascular networks and Myc-deficient embryonic stem cells

71 and mesenchymal progenitor cells (MPC) form vascular networks and restore blood flow in ischemic ske

72 form blood vessel-like structures, including vascular networks and sprouts.

73 een causatively linked to the elaboration of vascular networks and the regulation of capillary functi

74 representative areole (region bounded by the vascular network), and represent the volume of tissue wi

75 has an uneven growing front, a less-branched vascular network, and abnormal distribution of dll4-posi

76 , cell type, melanin content, mitotic count, vascular networks, and patients' age.

77 uronal and glial populations, interconnected vascular networks, and ramified microglia.

78 Pericytes are key to the maturity of these vascular networks, and therefore the ability of stem cel

79 s gap junction-mediated signaling across the vascular network are essential for proper capillary diam

80 ndothelial differentiation into a functional vascular network are incompletely understood.

81 Angiogenesis and the development of a vascular network are required for tumour progression, an

82 hat endothelial cells of the periventricular vascular network are the natural substrates for GABAergi

83 Plant vascular networks are central to botanical form, functio

84 The vascular networks are designed following in vivo images

85 ling of the vessel wall and the formation of vascular networks are dynamic processes that occur durin

86 Here we show that embryonic vascular networks are strategically positioned to fulfil

87 At the same time, vascular networks are susceptible to regression mediated

88 Leaf vascular networks are well-fitted to investigate this is

89 Expansion of vascular networks arises through sprouting angiogenesis,

90 were explanted and evaluated with regard to vascular network assembly and cell fate; and heterotypic

91 (NK-B), reversibly inhibits endothelial cell vascular network assembly and opposes angiogenesis in th

92 culminating with the formation of a complex vascular network available as a scaffold for cardiomyocy

93 escribe a new phenotypic trait of reticulate vascular networks based on the topology of the nested lo

94 eristics of polypoidal structures, branching vascular networks (BVNs), and origin of PCV using optica

95 onstrate prompt and consistent assembly of a vascular network by human ASCs and endothelial cells and

96 Formation of functionally adequate vascular networks by angiogenesis presents a problem in

97 Interestingly, the disruption of vascular networks by cancer cells was driven by changes

98 -canonical Wnt signalling stabilizes forming vascular networks by reducing endothelial shear sensitiv

99 llenge of predicting the hepatic multi-scale vascular network can be met thanks to the constructal la

100 regulated system, and generated subcutaneous vascular networks capable of systemic EPO release in imm

101 Inhibition of FZD4 in developing retinal vascular networks caused the upregulation of PLVAP, a pr

102 RAF(V600E), PLX4720 extensively modifies the vascular network causing abrogation of hypoxia.

103 with endothelial tubes, resulting in smaller vascular networks compared to those with healthy pericyt

104 These vascular networks connect at the lymphovenous (LV) junct

105 lial cells via VEGF granules, developing the vascular network critical for establishing pregnancy.

106 essed in 14/21 eyes (67 %) and the branching vascular network decreased in 1 eye and was stable in al

107 Computer-assisted quantification of this vascular network demonstrated considerable sensitivity o

108 ow modelling and polarity analysis in entire vascular networks demonstrates that polarization against

109 Vascular network density determines the amount of oxygen

110 Morphogenesis of hierarchical vascular networks depends on the integration of multiple

111 Blood vascular networks derived from implanted endothelial cel

112 Vascular networks develop from a growing vascular front

113 ctate via GPR81-Norrin participates in inner vascular network development and in restoration of the v

114 romotion of EC proliferation, migration, and vascular network development.

115 phangiogenesis results in the formation of a vascular network distinct from arteries and veins that s

116 microbeads, such as volume preservation and vascular network distribution, which may be beneficial f

117 d dynamic changes occurring to the lymphatic vascular network during TLS development have not been st

118 eling are essential for the establishment of vascular networks during organogenesis.

119 nesis, nascent vascular sprouts fuse to form vascular networks, enabling efficient circulation.

120 ich has a large, transparent, extracorporeal vascular network encompassing an area >100 cm(2) We foun

121 Thus, pre-patterned vascular networks enhance vascular remodeling and accele

122 choroidal telangiectases, abnormal choroidal vascular networks, exudative and hemorrhagic presentatio

123 zed to result from selection to maximize how vascular networks fill space yet minimize internal trans

124 The abnormal choroidal vascular network filled in the arterial or early venous

125 an increase in the value of lambda in tumor vascular networks following treatment with the antiangio

126 fabrication of highly perfusable and mature vascular networks for effective repair and regeneration.

127 signaling, greater senescence, and impaired vascular network formation and proliferation.

128 inistration of a pan-PP2A inhibitor disrupts vascular network formation and tumor progression in vivo

129 e spinal cord, providing novel insights into vascular network formation around developing organs.

130 , GPR81-null mice retina shows reduced inner vascular network formation associated with low levels of

131 human microvascular endothelial cell (HMVEC) vascular network formation in a 3-dimensional collagen g

132 lated human umbilical vein endothelial cells vascular network formation in a matrigel assay.

133 Downregulation of miR-145 in ASCs induce vascular network formation in ischemic muscle.

134 esults provide a framework for understanding vascular network formation in normal or pathological con

135 affold, preconditioned MPCs greatly enhanced vascular network formation in the infarct bed by mechani

136 ntly compromised in their ability to support vascular network formation in vitro and in vivo.

137 with Robo4, and accelerates endothelial-cell vascular network formation in vitro with a specific acti

138 -delta inhibited cell motility and lymphatic vascular network formation in vitro.

139 New vascular network formation is a critical step in the wou

140 on of the fibroblasts was required to induce vascular network formation via a transforming growth fac

141 sprouting is a critical process involved in vascular network formation within tissues.

142 el roles for pericytes during the process of vascular network formation.

143 helial cell viability, and proliferation and vascular network formation.

144 n-B2, and stimulated VEGF responsiveness and vascular network formation.

145 n regulating endothelial cell morphology and vascular network formation.

146 The density and complexity of vascular networks formed by the synergistic dual-cell sy

147 These ECFC-lined vascular networks formed functional anastomoses with the

148 applied tensile forces on the morphology of vascular networks formed within fibroblast and endotheli

149 Vascular networks formed within HA hydrogels containing

150 ertebrates, including birds and mammals, the vascular network forms throughout the embryonic disk wit

151 Vasculogenesis is the de novo formation of a vascular network from individual endothelial progenitor

152 ere were defects in formation of a primitive vascular network from SIRT1(-/-)-derived embryoid bodies

153 We further elaborate entangled vascular networks from space-filling mathematical topolo

154 source of mesenchymal stem cells (MSCs).New vascular networks from undifferentiated cells are essent

155 extension and anastomosis are the basis for vascular network generation, a process governed by the V

156 entered on the idea that the geometry of the vascular network governs how a suite of organismal trait

157 cal columns that are tightly linked with the vascular network, graph-theoretical analyses revealed th

158 Endothelial cells of the periventricular vascular network have molecular identities distinct from

159 ation of growth characteristics of the whole vascular network, head vasculature and tail vasculature

160 est acceptable grader agreement for the deep vascular network (ICC <0.85).

161 a in 33 eyes (69%) and an abnormal choroidal vascular network in 24 eyes (50%).

162 device platform with a microfluidics-modeled vascular network in a femoral arteriovenous shunt in rat

163 human endothelial cells formed a functional vascular network in immunocompromised mice with signific

164 nstrate photoacoustic microscopy of cortical vascular network in live mice over 28 days.

165 f two promising heme-targeting agents on the vascular network in mouse models of lung cancer, utilizi

166 wide range of tissue systems including fine vascular network in murine brain without craniotomy as w

167 In this study we exploited the hyaloid vascular network in murine eyes, which naturally undergo

168 To test this hypothesis, we evaluated the vascular network in spontaneously developing melanomas o

169 drives the formation of a robust and complex vascular network in the absence of exogenous growth fact

170 videnced a stage-dependent alteration of the vascular network in the cortices of fetuses with pFAS/FA

171 ignaling led to an organized recovery of the vascular network in the ischemic area.

172 ALCAM(-/-) mice displayed an altered blood vascular network in the lung and the diaphragm, indicati

173 rgoing abdominal aortic aneurysm repair in a vascular network in the South West of England.

174 re followed by the formation of an extensive vascular network in the stroma that supports embryonic g

175 51) mice, which lack ENS in the hindgut, the vascular network in this region appeared to be normal su

176 ve been investigated to include an organized vascular network in tissue constructs.

177 y detailed three-dimensional analysis of the vascular network in tumors.

178 es endogenous tissue dynamics to assembly of vascular networks in a mammalian system.

179 d quantitative analyses of three-dimensional vascular networks in all three models.

180 re, with reconstitution of rich intrainsular vascular networks in both species.

181 os showed a complete loss of high-complexity vascular networks in cotyledons and a drastic increase i

182 s can be a single source of odontoblasts and vascular networks in dental tissue engineering.

183 rongly support the use of human EPCs to form vascular networks in engineered organs and tissues.

184 rificial templates for patterning perfusable vascular networks in engineered tissues have been constr

185 ave focused on how stroke affects neural and vascular networks in experimental models of type 1 diabe

186 at neural activity promotes the formation of vascular networks in the early postnatal mouse barrel co

187 Blood vascular networks in vertebrates are essential to tissue

188 iate angiogenesis, and (iii) and intravasate vascular networks in vivo via a matrix metalloproteinase

189 ally resulted in the rapid regression of the vascular networks in vivo.

190 ferative and vasculogenic activity to create vascular networks in vivo.

191 red as a distinct area of hyperfluorescence (vascular network) in early to intermediate frames and as

192 of the major vessels of the trunk lymphatic vascular network, including the later-developing collate

193 s with the host circulation is essential for vascular networks incorporated within cell-seeded bioeng

194 We found that the enteric and vascular networks initially had very distinct patterns o

195 Yet the mechanism by which implanted vascular networks inosculate, or anastomose, with the ho

196 by pericytes and a role for gap junctions in vascular network interactions.

197 Assembly of these vascular networks involves sprouting, migration and prol

198 The microfluidics-based vascular network is a promising platform for generating

199 As it is altered by ionizing radiation, the vascular network is considered as a prime target in limi

200 enhances ischemia-induced remodeling of the vascular network is not known.

201 Establishment of a functional vascular network is rate-limiting in embryonic developme

202 onstrate that the expansion of the lymphatic vascular network is tightly regulated.

203 on and maintenance of blood flow through new vascular networks is essential for successfully treating

204 h to adulthood, but the normal patterning of vascular networks is maintained.

205 Angiogenesis, the growth and remodeling of a vascular network, is an essential process during develop

206 cyte coverage and formation of dense retinal vascular networks lacking the normal hierarchical arrang

207 nsity evident by CD31 staining as well as in vascular networks layered with smooth muscle cells when

208 signaling in the maturation of the lymphatic vascular network likely via regulating the perivascular

209 Assessing FAZ alterations in the deep vascular network may be subject to greater interobserver

210 Our results demonstrate that vascular network models cannot ignore certain complexiti

211 At the level of vascular network morphology, 7 months' diabetes induced

212 ng the primary tumor from developing its own vascular network needed for further growth.

213 monstrated that for insufficiently developed vascular networks, NPs are transported preferentially th

214 unolabeling and tissue clearing to image the vascular network of adult mouse brains and developed a p

215 By using the vascular network of EMBs, EMBs can be perfused ex vivo a

216 At the harvested site, the vascular network of episclera was not affected, and the

217 methods that allow examination of the intact vascular network of large organs, such as the human plac

218 apted to exert their immune functions in the vascular network of the liver.

219 During mouse development, the sophisticated vascular network of the lung is established from embryon

220 the stepwise assembly and patterning of the vascular network of the zebrafish hindbrain.

221 t explanations focus on predicting the whole vascular network or sprout from the underlying cell beha

222 eity of complex tissue networks, such as the vascular network or the respiratory tract.

223 Our aim was to elucidate alterations of the vascular network organization, taking advantage of Flk1(

224 omography angiography provided more distinct vascular network patterns that were less obscured by sub

225 eed (74 mm/s) navigation of a multi-branched vascular network phantom.

226 scular guidance genes and attenuated retinal vascular network progression.

227 Understanding the forces controlling vascular network properties and morphology can enhance i

228 Vascular network quantification by using high-spatial-re

229 The OCTA clearly identified vascular network rarefaction with decreased choriocapill

230 natal eye development, the embryonic hyaloid vascular network regresses from the vitreous as an adapt

231 lishing the anatomical form of the lymphatic vascular network remain largely unknown.

232 Importantly, the engineered vascular networks remained patent at 4 weeks in vivo.

233 for macrophages in supporting the extensive vascular network required for corpus luteum integrity an

234 of new capillary sprouts from a preexisting vascular network requires a highly coordinated cellular

235 Morphogenesis of a vascular network requires dynamic vessel growth and regr

236 ary and sufficient to trigger alterations of vascular networks reveals an important feature of neurov

237 are central determinants in the formation of vascular networks seen in vertebrate organisms.

238 The differences between vascular networks, sexes, and fellow eyes and correlatio

239 A comparison with the plant vascular networks shows that the same optimization crite

240 Simulations differing only in initial vascular network structures but with identical dynamics

241 cientists have long sought to understand how vascular networks supply blood and oxygen to cells throu

242 Vascular networks surrounding individual organs are impo

243 These engineered human vascular networks survive implantation, integrate with t

244 arts that exhibited an elaborate ventricular vascular network, Tbx5(epi-/-) hearts displayed a marked

245 These tumors also showed a more developed vascular network than control tumors and secreted elevat

246 As a result, an organized vascular network that is optimal for tissue perfusion is

247 characterized by an aggressive and aberrant vascular network that promotes tumor progression and hin

248 n and fabricate a liver-assist device with a vascular network that supports a hepatic parenchymal com

249 t uterus and the development of an elaborate vascular network that supports embryonic growth.

250 largely responsible for maintaining the fine vascular network that surrounds highly remodeling bone.

251 of the peri-neural vascular plexus (PNVP), a vascular network that surrounds the CNS and is critical

252 generate an extensive primitive plexus-like vascular network that would perfuse the entire scaffold

253 lid organs transport fluids through distinct vascular networks that are biophysically and biochemical

254 owth requires the development of independent vascular networks that are often primitive in morphology

255 ricyte-induced stabilization of newly formed vascular networks that are predisposed to undergo regres

256 sulted in self-organization of donor-derived vascular networks that connected to host vasculature, al

257 Angiogenesis produces primitive vascular networks that need pruning to yield hierarchica

258 d alone in vivo, they formed transient blood vascular networks that regressed by day 30.

259 uced the formation of dilated and normalized vascular networks that were hypersensitive to anti-VEGF

260 tion of the living device with the patient's vascular network, the development of biocompatible bioin

261 In the absence of perfusable vascular networks, three-dimensional (3D) engineered tis

262 ions with the LVV to safeguard the lymphatic vascular network throughout life.

263 ly suppresses JunB expression in the nascent vascular network, thus creating a gradient of this TF.

264 hat considers the average conductance of the vascular network to a representative areole (region boun

265 Immune cells rely on a functional vascular network to enter tissues.

266 the renal artery did not penetrate the renal vascular network to generate vessels; only administering

267 y achieved because of the confinement of the vascular network to one plane close to the surface of th

268 Engineered tissues need a vascular network to supply cells with nutrients and oxyg

269 P1 expression from the mature regions of the vascular network to the growing vascular front was obser

270 of water under tension, but also exposed the vascular network to the risk of gas emboli and the sprea

271 in perfusion and function: the patterning of vascular networks to efficiently deliver blood and nutri

272 equire high rates of perfusion by functional vascular networks to ensure proper sensory transmission.

273 cells and promotes the formation of abnormal vascular networks typical of KS vasculature; upregulates

274 nsport was simulated for a three-dimensional vascular network using parameters for rat extensor digit

275 gineering will rely on our ability to create vascular networks using human cells that can be obtained

276 The decellularized vascular network was able to withstand fluid flow that e

277 "margin," and "location," either because the vascular network was not clearly shown (3 cases) or beca

278 In addition, a branching vascular network was noted above the Bruch membrane in 1

279 ment of rCBF and vasodilation throughout the vascular network was observed in wild-type mice.

280 ion of abdominal aortic aneurysm repair in a vascular network was safe for patients and had no immedi

281 The vascular network was used to reseed the scaffolds with h

282 In this branched vascular network, WBCs have to strongly deform to pass t

283 map of all endothelial cells in a remodeling vascular network, we propose that balanced movement of c

284 face angiograms of the superficial and deep vascular networks were acquired.

285 Vascular networks were derived from the reconstruction.

286 cxcr4a mutant zebrafish fail to form a vascular network, whereas ectopic expression of Cxcl12b

287 cancer progression is the formation of a new vascular network which may originate from both pre-exist

288 y of aggressive cancer cells forming de novo vascular networks, which thereby contribute to perfusion

289 of-function causes formation of a hyperdense vascular network with disturbed blood flow.

290 Fli1 CKO mice showed a disorganized dermal vascular network with greatly compromised vessel integri

291 hat needs to be reorganized into a secondary vascular network with higher hierarchical structure.

292 somotor activity along a genetically defined vascular network with pharmacological and immunohistoche

293 is was confirmed by the presence of tortuous vascular networks with high levels of expression of CD31

294 f endothelial progenitor cells and generates vascular networks with perfusable lumens surrounded by m

295 bioengineering is the need for a functional vascular network within the engineered tissue.

296 muscle cells that surround and constrain the vascular network within the glomerulus of the kidney.

297 ased approach to generate endothelialized 3D vascular networks within cell-laden hydrogel biomaterial

298 mble into stable, multilayered and branching vascular networks within scalable microfluidic chambers,

299 s that can be pre-cultured to form primitive vascular networks within the modular structures.

300 ows for the evaluation of functional retinal vascular networks without a need for contrast dyes.