ライフサイエンスコーパス: vascularity

1 animal to detect mural inflammation or tumor vascularity.

2 pt and survive long-term reductions in islet vascularity.

3 nce useful in the assessment of brain tumors vascularity.

4 in the process of evaluation of intratumoral vascularity.

5 cells and was associated with reduced tumor vascularity.

6 evidence of neuronal recovery with increased vascularity.

7 eated mice, correlating with decreased tumor vascularity.

8 r mucosal wounds, nor did it alter wound bed vascularity.

9 ha expression and marked inhibition of tumor vascularity.

10 ta cells, in the absence of changes in islet vascularity.

11 fects on ECM remodeling and increased muscle vascularity.

12 odels, concomitant with an increase in tumor vascularity.

13 xpression of IL-17 in mouse ankles increases vascularity.

14 lved in tumor-stromal interactions and tumor vascularity.

15 ncreased VEGF-A, reduced IL-33, and enhanced vascularity.

16 ewer endothelial cells indicative of reduced vascularity.

17 luences endothelial cell migration and tumor vascularity.

18 ion reduced pericytes without reducing tumor vascularity.

19 microvessel density and other indicators of vascularity.

20 severity and more prominent inflammation and vascularity.

21 sessment of intratendinous and peritendinous vascularity.

22 immune composition, cytokine expression, and vascularity.

23 bility of WT HSV to increase infected tissue vascularity.

24 pressing prostate growth by targeting tissue vascularity.

25 ound healing was notable for increased wound vascularity.

26 stered locally did not alter tumor growth or vascularity.

27 ents, the lesions were hyperechoic with poor vascularity.

28 mor, delay of tumor growth, and intratumoral vascularity.

29 s were also immunostained for CD31 to assess vascularity.

30 achment of pericytes and disruption of tumor vascularity.

31 ing iris melanocytic lesions, for growth and vascularity.

32 nt status, or histologic assessment of tumor vascularity.

33 0.1) for bleb height, and 3.4 (0.2) for bleb vascularity.

34 ncreased proliferation, tumor outgrowth, and vascularity.

35 nd diabetes reversal, due to hypoxia and low vascularity.

36 kles and the IPE cyst did not have intrinsic vascularity.

37 nically exposed to hypoxia owing to aberrant vascularity.

38 vascular structures and quantify intestinal vascularity.

39 erage of tumors, depending on their size and vascularity.

40 pair, irrespective of fracture stability and vascularity.

41 patterning that results in high interdigital vascularity.

42 s-like enhancement associated with increased vascularity.

43 The treated group also revealed less vascularity (1.6 +/- 0.1 units vs. 1.1 +/- 0.0 units; P

44 s in granuloma formation (30%) and granuloma vascularity (42%) in a murine chronic inflammation-induc

45 led that the tumors have evidence of reduced vascularity after treatment.

46 parenchyma and lesion signal intensities and vascularity, airway, esophagus, and diaphragm appearance

47 specifically into BAT of obese mice restored vascularity, ameliorated brown adipocyte dysfunction, an

48 F and PDGF inhibition together reduced tumor vascularity and abundance of pericytes.

49 ut the change was less than the reduction in vascularity and actually increased when expressed per su

50 reproducible technique for quantifying tumor vascularity and angiogenesis in advanced HCC.

51 period ameliorates inflammation and restores vascularity and beta-cell function into adulthood, demon

52 1 in animals with an established neuropathy, vascularity and blood flow returned to levels similar to

53 proteins involved in regulating white matter vascularity and blood flow.

54 The increased vascularity and bone regeneration in the pVHL mutants we

55 Cell implantation markedly improved vascularity and cardiac function after myocardial infarc

56 rmacologic induction of bradycardia enhances vascularity and coronary reserve, preserves function of

57 lthough some markers of tumor growth such as vascularity and cyclin D1 expression are suppressed, pri

58 is sometmies impossible because of the rich vascularity and difficult location.

59 If the vascularity and echogenicity of the scrotal mass is simi

60 cs of tissue that surrounds tumor, including vascularity and electric conductivity, affect ablation o

61 e depends on the stage of tumor development (vascularity and endothelial receptor expression) and the

62 own adipose tissues of KO mice, with greater vascularity and enhanced browning and thermogenesis.

63 retrospective studies was to evaluate tumor vascularity and expression of components of the VEGF pat

64 umour cell implantation, with reduced tumour vascularity and extensive necrosis.

65 maging, additional tissue properties such as vascularity and fibrosis can be demonstrated.

66 of ATME physiology, including inflammation, vascularity and fibrosis, and discuss therapeutic interv

67 especially in the setting of typical lesion vascularity and friability.

68 on, treatment with bevacizumab reduces tumor vascularity and growth.

69 it results in a permanent reduction in islet vascularity and impaired insulin secretion.

70 nd endothelial cells, resulting in increased vascularity and improved cardiac function.

71 enchymal-to-endothelial transition, enhances vascularity and improves cardiac function.

72 are malignant tumors characterized by their vascularity and invasive capabilities.

73 erative and apoptotic activities, as well as vascularity and macrophage infiltration that correlated

74 olesions' together with a global increase in vascularity and microglia.

75 Vascularity and myeloid suppressor cell populations and

76 romotes progression through effects on tumor vascularity and myeloid suppressor cell populations, in

77 Increased vascularity and neoangiogenesis have been implicated in

78 e was associated with enhanced intralesional vascularity and neutrophilic inflammation, which are hal

79 effects of glucose and inflammation on islet vascularity and on beta function, mass, and insulin in i

80 entify Vegfa as a regulator of perichondrial vascularity and osteoblast differentiation at early stag

81 rine growth restriction (IUGR) on pancreatic vascularity and paracrine signaling between the EC and b

82 rectal cancer can enable assessment of tumor vascularity and perfusion changes that result from chemo

83 y period results in augmentation of lesional vascularity and perfusion, as well as improved motor rec

84 st cancer appears to predict increased tumor vascularity and perhaps cancer dissemination by hematoge

85 re the biologic effects of the drug on tumor vascularity and permeability.

86 y be related to factors altering endometrial vascularity and permeability.

87 vation in osteoblasts had markedly increased vascularity and produced more bone in response to distra

88 relationships between anaplasia, tumor size, vascularity and prognosis, and local recurrence seeded b

89 Preserved vascularity and reduced inflammation correlated with imp

90 iority in an order reflecting superiority of vascularity and resistance to radiation: latissimus dors

91 Ultrasonographically determined vascularity and septation were not statistically signifi

92 AMG 386 also appeared to impact tumor vascularity and showed antitumor activity in this patien

93 significantly increased cell proliferation, vascularity and synaptogenesis, as well as reduced apopt

94 d regression that are respectively linked to vascularity and tumor cell alterations, including cellul

95 s the VEGF blocker aflibercept reduced tumor vascularity and tumor perfusion more dramatically than e

96 In addition to angiographic data on vascularity and vascular access, demonstration of hepato

97 inclusion of vascular factors such as tumor vascularity and vascular involvement, ulceration was no

98 a and is associated with increased bronchial vascularity and vascular permeability.

99 lating VEGF-A expression may influence islet vascularity and, consequently, the amount of insulin del

100 ession may be a means to regulate lymph node vascularity and, potentially, immune function.

101 creas showed increase in cell proliferation, vascularity, and abnormal vascular structures; such chan

102 stroma have a differentiated phenotype, low vascularity, and are associated with a favorable prognos

103 hemoglobin levels, suggesting reduced joint vascularity, and both endothelial cell migration and tub

104 Flap angiography confirmed intact vascularity, and computer tomography scan and histology

105 eatment led to delayed tumor growth, reduced vascularity, and decreased lung metastasis.

106 ations in lipid regulatory factors, enhanced vascularity, and decreased M1/M2 macrophage ratios may a

107 nts may decrease tumor contrast-enhancement, vascularity, and edema, the mechanisms leading to improv

108 irway smooth muscle (ASM), mucus gland area, vascularity, and epithelial integrity.

109 TNFalpha-associated tumor growth, vascularity, and generation of tumor vascular leukocytes

110 their ability to inhibit tumor angiogenesis, vascularity, and growth.

111 ibited undifferentiated histology, increased vascularity, and heightened proliferation--features that

112 en I deposition, decreased cellularity, less vascularity, and higher glycosaminoglycan content when c

113 Granulation tissue area, vascularity, and IGF1 and EGF receptor phosphorylation a

114 pitulates tumor heterogeneity, invasiveness, vascularity, and immunosuppressive microenvironment in s

115 he overall size of claustrum, its pronounced vascularity, and its more complex intrinsic connectivity

116 proliferation, increased fibrosis, increased vascularity, and mast cell infiltration.

117 owth, numbers of metastases to major organs, vascularity, and perfusion between SU5416-treated and co

118 oved scarring in terms of height, thickness, vascularity, and pigmentation (12 months and 18-24 month

119 ingival tissue eases manipulation, maintains vascularity, and promotes wound healing during and after

120 Choroidal thickness, choroidal vascularity, and retinal vessel density were measured ac

121 translucent structure, granularity, fibrin, vascularity, and stool after oral or rectal allergen cha

122 ranslucency, granularity, fibrin production, vascularity, and stool.

123 ce of a capsule, homogeneity, the pattern of vascularity, and washout.

124 , in human prostate cancer cells and reduced vascularity (angiogenesis) in vivo using Matrigel plug a

125 Ageing reduced vascularity ( approximately 50%, P < 0.01), angiogenic c

126 onments associated with inflammation or poor vascularity are encountered in vivo.

127 way smooth muscle, extracellular matrix, and vascularity are prominent features of airway remodeling

128 CAM treated with EMD displayed moderate vascularity as indicated by a maximal score of 3.0 +/- 0

129 ), as was the total color Doppler area (CDA; vascularity assessment) (median reduction 100% and 47.1%

130 ockade resulted in markedly increased tumour vascularity, associated with enhanced angiogenic sprouti

131 and changes in synovial thickening and joint vascularity at 18 weeks, we were able to distinguish tho

132 phic measurements of synovial thickening and vascularity at baseline in the placebo + MTX group demon

133 of microerosions (P < .0001), and increased vascularity at the squamocolumnar junction (OR, 9.3; 95%

134 ibomian gland quality, orifice plugging, lid vascularity) between patients with PTSD or depression an

135 ssociated with a prominent decrease in tumor vascularity (blood and lymph vessels), likely due to red

136 e transfer exhibited significantly decreased vascularity both in an orthotopic and in an ectopic mode

137 ling can block angiogenesis and reduce tumor vascularity, but little is known about the reversibility

138 hibitor of VEGF signaling, reduced the tumor vascularity by 86%.

139 erazine, non-invasive visualization of tumor vascularity by bioluminescence imaging was possible.

140 gic assessment of hypoxia (pimonidazole) and vascularity (CD31).

141 biology by probing characteristics of tumour vascularity, cellularity and metabolism which critically

142 Tumor vascularity changes during treatment were assessed from

143 collagen alignment and an advanced state of vascularity compared to control treatments.

144 C chemokines (ie, the ELR score) and greater vascularity compared with tumors in which MIF-CD74 co-ex

145 Early differences in vascularity correlated with later bone development.

146 nsgenic mice, where pericytes decreased 47%, vascularity decreased 38%, and basement membrane sleeves

147 Overall tumor vascularity decreased 79% over 28 days, without a corres

148 t resulting in significantly increased wound vascularity, dermal thickness, collagen deposition and t

149 he hypothesis that abnormal gastrointestinal vascularity develops during continuous-flow LVAD support

150 Intratumoral vascularity did not correlate with either tumor size or

151 n following POH, while preserving myocardial vascularity, does not prevent mitochondrial and contract

152 +) will improve histological measurements of vascularity, fibrosis, and inflammation in human subject

153 ing CNR and providing increased perilesional vascularity, Gadovist can help in the determination of m

154 Plaque vascularity has been implicated in its growth and stabil

155 or receptor (EGFR) associated with increased vascularity has been implicated in the pathogenesis of F

156 issue, and glandular tissue contains greater vascularity, hence, more total hemoglobin.

157 t felt pain), Ultrasonographic (size, depth, vascularity, heterogenous features, septae) and MRI (siz

158 nous features, septae) and MRI (size, depth, vascularity, heterogenous features, septae, complete fat

159 tivation was associated with decreased islet vascularity, highlighting the proposed role of endotheli

160 y with RTKIs abrogated the increase in islet vascularity, impairing T-cell migration into the islet a

161 maging depicted an absence of residual nidus vascularity in 32 (76%) of the 42 patients who were trea

162 ranulation tissue reconstitution, and tissue vascularity in a murine model of repair stimulation.

163 ation of FLLL32 can inhibit tumor growth and vascularity in chicken embryo xenografts as well as subs

164 m of this study was to evaluate interstitial vascularity in cryptogenic fibrosing alveolitis (CFA) an

165 ffered due to reduced central and peripheral vascularity in MMC group (P = 0.027; P = 0.041).

166 T whitening, supporting a role for decreased vascularity in obesity-associated BAT.

167 method for longitudinal monitoring of tumor vascularity in response to the anti-angiogenic drug tivo

168 By contrast, there was only mild vascularity in sections treated with the negative contro

169 enable the in-vivo visualization of abnormal vascularity in synovium and subchondral bone that have n

170 after 4 days and a 2.8-fold increase in the vascularity in the dermis that peaked after 2 days.

171 nified layer (hyperkeratosis), and increased vascularity in the dermis.

172 ional liver tissue is limited by the lack of vascularity in the tissue-engineered constructs.

173 ficant suppression of tumor growth and tumor vascularity in vivo by targeting Akt and focal adhesion

174 Vascularity in whole knees and distal femora was signifi

175 In 2 eyes with nevi there was no increased vascularity; in another, fine vascular loops were noted

176 Changes in tumor size, pigmentation, and vascularity; incidence of iris neovascularization; and r

177 Rosuvastatin restored nerve vascularity, including vessel size, and nerve function a

178 prominent increase in CNR, and perilesional vascularity increase are important findings determining

179 increase in CNR, and absence of perilesional vascularity increase support findings of benign breast l

180 By contrast, 10% O2 impaired fetal vascularity, increased barrier thickness and reduced pla

181 Tumors had decreased volumes, decreased vascularity, increased CTL infiltrate, and Nrp1-depleted

182 cination of tumor-bearing mice reduced tumor vascularity, increased infiltration of CD3+ T cells into

183 hytherapy included decreased intrinsic tumor vascularity, increased tumor pigmentation, and decreased

184 The choroidal vascularity index (CVI) has been shown to be sensitive i

185 Choroidal vascularity index (CVI) was calculated in all study eyes

186 (TCA), luminal area (LA), and the choroidal vascularity index (CVI) were calculated after image bina

187 ean choroidal thickness (MCT), and choroidal vascularity index (CVI) were investigated using swept so

188 CVV), choroidal stroma volume (CSV), choroid vascularity index (CVI), and the choroidal stroma-to-ves

189 found between the pattern of vascularity or vascularity index before or after contrast material admi

190 The tissue samples were analyzed for vascularity, inflammatory cell infiltration, growth patt

191 ized by large areas of apoptosis, diminished vascularity, inhibition of hyperplasia in overlying epid

192 r solid tumors and metastatic lesions, tumor vascularity is a critical factor in assessing response t

193 Nonischemic muscle vascularity is also lower in Y2(-/-) mice, whereas it is

194 quence of PDGF-B blockade, but reduced tumor vascularity is likely to be secondary to pericyte regres

195 In infected tumors, this increased vascularity is mediated by reduced TSP-1 and TSP-2 level

196 ther this ability to enhance infected tissue vascularity is retained in oncolytic HSV, which could be

197 This increased vascularity lacked functionality, correlating with enhan

198 , vasoconstriction and altered expression of vascularity markers in skin and internal organs, early i

199 Therefore, we hypothesized that increased vascularity may be associated with improved outcomes in

200 Quantitative Doppler US vascularity measurements considerably contribute to mali

201 gist-defined ellipsoid, in which six Doppler vascularity measures were calculated.

202 lioblastoma, including tumor cellularity and vascularity, metabolite expression, and patterns of tumo

203 For intrinsic vascularity (n = 19), 12 tumors (63%) showed decrease an

204 Permanent reductions in placental vascularity occurred during the earlier but not the late

205 aphic (CT) perfusion for evaluation of tumor vascularity of advanced hepatocellular carcinoma (HCC) a

206 dministration resulted in increased size and vascularity of CNV, and older mice developed a greater r

207 CL(2)MDP-lip reduces size, cellularity, and vascularity of CNV.

208 Perfusion CT measurements may measure vascularity of colorectal tumors, however, correlation w

209 ma4D shRNA reduces dramatically the size and vascularity of HNSCC tumor xenografts.

210 ro endothelial cell migration and growth and vascularity of HNSCC xenografts expressing a degradation

211 xamination of two cases showed intralesional vascularity of mild-to-moderate degree.

212 Size and vascularity of MNV imaged with OCTA before and after the

213 NFalpha expression promoted tumor growth and vascularity of mouse melanoma, lung cancer, and mammary

214 mice with XL999 resulted in 43% reduction in vascularity of spontaneous pancreatic islet tumors over

215 m the avascularity of thrombi and the sparse vascularity of stromal tumors.

216 The enhanced vascularity of the -/- tumors is particularly significan

217 The vascularity of the 5-kDa EMD-protein fraction was not di

218 pothesized that this is related to the local vascularity of the bone.

219 of 7.5-10 MHz to observe the morphology and vascularity of the eyeball was applied.

220 ppression of innate immune signaling reduced vascularity of the Matrigel plug and abrogated the gener

221 om the OCTA images, we assessed the size and vascularity of the MNV.

222 derstanding may help clinicians optimize the vascularity of the recipient bed to further improve fat

223 nd imaging is used to determine the size and vascularity of the thyroid gland and the location, size,

224 marrow transplantation models, the enhanced vascularity of the wound was shown to be mediated, at le

225 rowth factor (VEGF) signaling can reduce the vascularity of tumors and leakiness of surviving vessels

226 pact of increased PHIP copy number and tumor vascularity on ulceration status was highly significant

227 correlation was found between the pattern of vascularity or vascularity index before or after contras

228 d not affect tumor proliferation, apoptosis, vascularity, or lymphocyte infiltration.

229 the number of reported adverse events, bleb vascularity, or morphology between the 2 groups.

230 .021), and gross appearance of intratumoral vascularity (P = .018).

231 scribed oval mass (P = .024) at mammography, vascularity (P = .047) and posterior enhancement (P = .0

232 (P = .625), bleb extension (P = .216), bleb vascularity (P = .672), or complications rates.

233 > .999), ectropion (P > .999), and intrinsic vascularity (P = .70).

234 3 times less ischemia and greater peripheral vascularity (P = 0.001) than control animals treated wit

235 d that ligands for CRFR2 act to limit tissue vascularity, perhaps as a counterbalance to factors that

236 ealing wounds as controls, and the increased vascularity persisted for at least 2 weeks.

237 lar keratitis, by increasing infected tissue vascularity, possibly reflecting altered angiogenic fact

238 nopposed action of Ang1, but decreases tumor vascularity primarily by blocking Ang2 actions.

239 The decrease in vascularity produced by SelCID treatment is attributed t

240 ormalization, but not the reduction in tumor vascularity produced by the Ang2 inhibitor.

241 tion of signaling pathways that govern tumor vascularity provide a potential avenue to thwart cancer

242 , no Doppler feature, including intranodular vascularity, pulsatility index, resistive index, or peak

243 rrelated significantly with histologic tumor vascularity (r = 0.83; P < 0.001).

244 l tumors attached to peritoneal organs, with vascularity ranging from 2% to 10%, also show enhanced d

245 Tumour growth was retarded and vascularity reduced in clec14a(-/-) mice.

246 reased circulating EPC counts and myocardial vascularity, reduced fibrosis, and improved cardiac func

247 e genetic program with increased scar border vascularity, reduced fibrosis, and recovery of pumping f

248 Features that were evaluated included lesion vascularity relative to the adjacent cortex in the arter

249 surface area (in relative disc areas or DA), vascularity (relative fluorescence), and cellularity (pr

250 tial for direct nose to brain delivery, high vascularity, relatively large absorptive surface area, a

251 er differences observed in RBM thickness and vascularity result from disease or normal age-related de

252 Tumor vascularity seems to be a precursor of both vascular inv

253 Increasing tumor vascularity significantly increased the risk of relapse

254 Interestingly, adventitial vascularity significantly increased, suggesting a mechan

255 the immunohistochemical assessment of tumor vascularity (SMA and CD34 counts) (P < .003).

256 ovides dynamic real-time assessment of tumor vascularity so that contrast enhancement can be identifi

257 This compared favorably to the degree of vascularity stimulated by the mixture of fibroblast grow

258 alternative driver of excessive and abnormal vascularity that fuels cancer progression and immunosupp

259 f the synovium, its thickening and increased vascularity through ultrasound and magnetic resonance ex

260 y TCDD were associated with effects on tumor vascularity, tumor cell proliferation and/or apoptosis.

261 e developed a novel approach to assess tumor vascularity using recombinant Gaussia luciferase (rGluc)

262 itreous inflammation, retinal structure, and vascularity using swept-source OCT (SS-OCT) and OCT angi

263 hin the hydrogels and significantly improved vascularity, ventricular geometry, ejection fraction, ca

264 ith vascular involvement and increased tumor vascularity versus matched controls lacking these factor

265 Immunohistochemistry was employed to measure vascularity (vWF), neurogenesis (BrdU TUJ1, DCX and NeuN

266 relationship between stromal Sdc1 and tumor vascularity was also examined in a tissue array containi

267 The fact that vascularity was also increased by recombinant human amel

268 Vascularity was also increased by recombinant human amel

269 Subchondral bone plate vascularity was altered with increasing stages of OA.

270 Tumor vascularity was assessed from total Hb (tHb), oxygenated

271 Similarly, vascularity was consistently lower in the tumor center c

272 Bleb vascularity was graded on a scale of 1 to 5 (1 indicatin

273 d to control eyes with emmetropia, choroidal vascularity was greater in eyes with high myopia (beta =

274 Vascularity was higher in group 1 than in group 2 (P = 0

275 Lung vascularity was increased by MFN2.

276 d fibrosarcomas was impaired, although tumor vascularity was increased.

277 Paradoxically, this increased vascularity was non-productive-as shown by poor perfusio

278 On color Doppler US, no vascularity was observed in the heterogeneous testicular

279 Vascularity was present in all lesions (n = 94) at contr

280 At the higher amounts, vascularity was reduced and not significantly different

281 number of sprouts was reduced by 82%, tumor vascularity was reduced by 67%, and tumor growth slowed

282 Histologic analysis revealed that vascularity was reduced in sEphB4-treated membranes.

283 Intestinal vascularity was significantly higher after LVAD support

284 Change in wound bed vascularity was significantly lower in oral wounds than

285 ailed to penetrate grafts, and after 2 weeks vascularity was still disturbed.

286 Using the Power Doppler callus vascularity was visualized and vascular resistance index

287 Tumor permeability and vascularity were assessed by calculating the bidirection

288 Nevertheless, muscle insulin action and vascularity were increased.

289 orescence imaging, alterations in knee joint vascularity were quantified with muCT after perfusion of

290 ous, homogenous), and perilesional increased vascularity were studied.

291 ate analysis, vascular involvement and tumor vascularity were the strongest predictors of melanoma ou

292 blood perfusion, cellular proliferation, and vascularity were visualized using Hoechst 33342, bromode

293 s correlated with the normalization of tumor vascularity when injected during tumor growth and with t

294 elling of specific CSPGs as well as enhanced vascularity, which was closely associated with CD206-pos

295 ) and foveal (1.5 mm) regions, and choroidal vascularity, which was determined by dividing vascular a

296 ealed that VEGFR-2 was confined to the islet vascularity, which was increased in inflamed islets.

297 or's environment (eg, stromal matrix, tissue vascularity),will likely enable improved treatment strat

298 ssociated increase in mesenteric and colonic vascularity with an increase in mean signal intensity of

299 ssociated increase in mesenteric and colonic vascularity with an increase in mean signal intensity of

300 onfiguration, lesion pigmentation, intrinsic vascularity within the lesion, presence of associated pi

301 However, VEGF inhibition reduced tumor vascularity without decreasing pericyte density, and PDG