ライフサイエンスコーパス: vasculature

1 -printed phantoms representing the patient's vasculature.

2 graphy (OCTA), capable of visualizing retina vasculature.

3 component of functional flow sensing in the vasculature.

4 s, and to endothelial cells to stabilize the vasculature.

5 up the valves and a portion of the coronary vasculature.

6 rograde electrical signaling in the cerebral vasculature.

7 e focus on factors that are extrinsic to the vasculature.

8 tinct from the radially oriented normal iris vasculature.

9 ies by promoting active migration within the vasculature.

10 growth factor-beta signaling in tumor blood vasculature.

11 dherent to the entire mucosal lamina propria vasculature.

12 for regulating control of the human retinal vasculature.

13 y regulated transcription factors within the vasculature.

14 mplex set of factors required to form stable vasculature.

15 nical BR signaling and RLP44 function in the vasculature.

16 and inhibits the formation of a normal skin vasculature.

17 vessel as the catheter advances through the vasculature.

18 degrade the visualization of the underlying vasculature.

19 s bubbles to provide acoustic backscatter in vasculature.

20 ke with atherosclerotic stenosis of cerebral vasculature.

21 ural cells and a lack of functional glia and vasculature.

22 ges to emphasize the contrast agent-enhanced vasculature.

23 ence interval: 1.3, 17; P = .02) the central vasculature.

24 length, and decreased lignin content in root vasculature.

25 nd the extravasation of tumor cells from the vasculature.

26 odialysis but cannot demonstrate the central vasculature.

27 esses required to form a functional coronary vasculature.

28 and restored blood flow in tumor-associated vasculature.

29 ions, even in the setting of uninjured adult vasculature.

30 riate expansion and function of the coronary vasculature.

31 employ to promote their movement through the vasculature.

32 dduction, deforms the disc and peripapillary vasculature.

33 hroughput automated analysis of the cerebral vasculature.

34 nditioned by the geometry of the surrounding vasculature.

35 as astrocyte endfeet more fully ensheath the vasculature.

36 ing physical interaction with the developing vasculature.

37 modelled by a local occlusion of the tumour vasculature.

38 epidermis, cortex and stele, and to the leaf vasculature.

39 maintains the quiescent phenotype of resting vasculature.

40 of angiogenic functions in the peri-ischemic vasculature.

41 t for immune-mediated injury of the coronary vasculature.

42 r progenitors, other endodermal lineages, or vasculature.

43 cells, stroma, angiogenic molecules, and the vasculature.

44 ssue and the eventual collapse of the entire vasculature.

45 lations found in the native organ, including vasculature.

46 of talin1 expression, a regulator of hyaloid vasculature.

47 alf-life, offering protracted delineation of vasculature.

48 docardial-derived cardiac valve, septum, and vasculature.

49 a protease family with unknown functions in vasculature.

50 ion in addition to peripapillary superficial vasculature.

51 to exposed collagen in the disordered tumour vasculature.

52 pheral lymph nodes and map phenotypes to the vasculature.

53 mphatic activity and the meningeal lymphatic vasculature.

54 l mesothelial cells (AMCs), and the coronary vasculature.

55 ascular defect with disorganized and reduced vasculatures.

56 We identified in the normal cerebroretinal vasculature a novel segment between arterioles and capil

57 cancer cells predominantly adhered to nearby vasculature, about 30% invaded the non-vascularized tiss

58 made possible by two unique features of CNS vasculature absent in the peripheral organs.

59 in addition to macular superficial and deep vasculature after projection removal using custom softwa

60 , the quiescent center (ERF104) and the root vasculature (all).

61 lymphatic sprouts originating from lymphatic vasculature along the dural sinuses and the middle menin

62 ophoblasts (CTBs) invades the uterus and its vasculature, anchoring the pregnancy and ensuring adequa

63 clots to wounds is necessary to seal injured vasculature and achieve hemostasis.

64 trate that implants survived, retained human vasculature and anastomosed with the circulatory system

65 sential for angiogenesis, maintenance of the vasculature and are key players in microvascular patholo

66 However, the cortical vasculature and associated directional blood pooling tow

67 ymph nodes, causing reorganization of tumour vasculature and cancer cell death, a process dependent o

68 DiI and DAPI were used to stain the coronary vasculature and cardiomyocyte nuclei in quail embryo hea

69 Here we sought to characterize putative vasculature and cartilage to bone transdifferentiation u

70 ese procedures, a real-time visualization of vasculature and CBF was available in high spatial resolu

71 a molecular roadmap of the lymph node blood vasculature and defines subset specialization for leukoc

72 s resulted in viable offspring and remodeled vasculature and did not recapitulate the betaA-Akt1WT/fl

73 ension due to macrophage infiltration of the vasculature and direct activation of renal juxtaglomerul

74 chemistry was used to evaluate the lymphatic vasculature and donor-host connections after lung transp

75 rent types of noncoding RNAs controlling the vasculature and focus on the developing field of long no

76 lating permeability in discrete areas of the vasculature and highlight the inherent limitations of th

77 dow was prepared to allow access to cortical vasculature and imaged using 2D-optical imaging spectros

78 through SASP-dependent effects on the tumor vasculature and immune system.

79 ted in intracellular membranes in the nodule vasculature and in inner nodule tissues, as well as in t

80 p showed Se to accumulate mainly in the leaf vasculature and in the seed embryos, with predominant Se

81 vivo, combination treatment decreased tumor vasculature and increased tumor necrosis in comparison w

82 es including the collecting ducts, nephrons, vasculature and interstitium.

83 We define the complexity of the cardiac vasculature and its changes along the arterio-venous axi

84 ught to study the effect of milrinone on the vasculature and its effects on the ventricular function

85 east average image quality, in which retinal vasculature and landmarks could be visualized.

86 ure, mildly stunted growth of the cerebellar vasculature and little or no effect on the vasculature e

87 2(443) promoted destabilization of pulmonary vasculature and lung metastasis.

88 ermore, our data show progressive changes in vasculature and maturation of dendritic-cell subsets wit

89 o microscale visualization of deep medullary vasculature and neuronal perikarya.

90 Changes in retinal vasculature and ocular circulation may play an important

91 rovides high-resolution images of the tumour vasculature and of the surrounding tissue, and that the

92 nd provides real-time visualization of tumor vasculature and perfusion.

93 in + Gd solution transiting through cerebral vasculature and persistent hyperintensities indicated oc

94 chanotransduction in the postnatal lymphatic vasculature and posit cytoskeletal signaling as a therap

95 ds to pathologic remodeling of the pulmonary vasculature and pulmonary hypertension (PH).

96 A in miniature pigs, we discovered increased vasculature and putative chondrocyte to osteoblast trans

97 l sympathetic outflow to the skeletal muscle vasculature and reset vascular-sympathetic baroreflex co

98 ciated trophic role in maintaining choroidal vasculature and RPE cells, implicating insufficiency in

99 This leads to the robust assembly of vasculature and the deposition of new basement membrane.

100 n for fibrin(ogen) deposited on the inflamed vasculature and to directionally spread, to polarize and

101 re performed to visualize the metatarsus and vasculature and to fabricate customized scaffolds and su

102 To account for spatial variations in the vasculature and tumor tissue that occur during tumor gro

103 g the whole neuraxis, including the cerebral vasculature and, in some cases, responding to immunother

104 genitor cells (HSPCs) involves homing to the vasculatures and lodgment to their niches.

105 pulp, which is vital tissue rich with cells, vasculature, and nerves in the inner tooth.

106 In contrast, tracheal cartilage, vasculature, and neural innervation patterns were all di

107 l distension of the ER, normalizes the tumor vasculature, and remodels the cellular TME, attenuating

108 loading zone and guard cells in leaves, root vasculature, and shoot apical meristem, implicating it i

109 nal meninges, contrast agent-enhanced spinal vasculature, and spinal nerves were all well rendered al

110 e BP is regulated by the function of kidney, vasculature, and sympathetic nervous system, recent expe

111 hat travel further to innervate the skin and vasculature, and their functional impact will require co

112 anscriptomes and morphogenic patterns of the vasculature are distinct from processes in inflammation

113 d sonodynamic therapy strongly affects tumor vasculature as determined by dynamic contrast enhanced i

114 cur where cell populations outgrow the local vasculature, as observed in solid tumors.

115 determined that microglia associate with the vasculature at all ages in areas lacking full astrocyte

116 nsional display of bone, nervous tissue, and vasculature at microscale resolutions without exogenous

117 asively evaluate temporal changes in retinal vasculature at very early stages of diabetes using fundu

118 TRPV1 expression in isolated segments of the vasculature, but whether the channel localizes to vascul

119 CER2 sustains the integrity of the placental vasculature by controlling the homeostasis of sphingolip

120 in sustaining the integrity of the placental vasculature by regulating the homeostasis of sphingolipi

121 Replenishment of the vasculature by the endodermis depends on the transcripti

122 Blood flow in the vasculature can be characterised by dimensionless number

123 astoma, we show that the meningeal lymphatic vasculature can be manipulated to mount better immune re

124 ng paper showing how the meningeal lymphatic vasculature can be manipulated with VEGF-C to promote an

125 Action on the heart and vasculature can cause potentially lethal arrhythmias, of

126 eficient mice exhibited abnormalities in the vasculature causing partial lethality of embryos and neo

127 tissue healing and remodelling of the blood vasculature, causing cancer cell hypoxia and death in di

128 ability to cross a single barrier (i.e. the vasculature, cell membrane, or endosomal compartment), b

129 cGAMP transporters in resting primary human vasculature cells and universal human cGAMP transporters

130 gence of peripapillary and macular capillary vasculature changes after I(125) plaque brachytherapy.

131 rophages, as well as components of the renal vasculature, control purinergic receptor-mediated effect

132 rved mainly in stroma, leukocytes, and tumor vasculature, corresponding to a role of complement in re

133 ticle-mediated drug delivery targeting tumor vasculature coupled with numerical optimization to pursu

134 nfection, tissue scarring, inflammation, and vasculature damage, as well as efforts to manage these d

135 Genes associated with vasculature development and blood vessel morphogenesis s

136 igger pits, thinner pit membranes, perturbed vasculature development, lower reproductive potential an

137 pe, while confining MtFPN2 expression to the vasculature did not improve the mutant phenotype.

138 Monocytes recruited to the glomerular vasculature did not undergo transendothelial migration.

139 Knockdown of CsIVP caused severe vasculature disorganization and abnormal organ morphogen

140 ine upregulation, accumulate in the ischemic vasculature during hyperacute stroke and may affect outc

141 r percentage of microglia associate with the vasculature during the first week of postnatal developme

142 r vasculature and little or no effect on the vasculature elsewhere in the central nervous system (CNS

143 ening on transmitted pulsatility to cerebral vasculature, employing a computational approach using a

144 cture in the ventral optic cup through which vasculature enters the eye and ganglion cell axons exit.

145 l ossification, the presence of fully formed vasculature expressing CD31(+) endothelial cells and alp

146 eal niche of the bone marrow (BM) toward the vasculature, extending proplatelets into sinusoids, wher

147 of VEGF signaling phenocopied the pax2a(-/-) vasculature, F-actin and BM degradation phenotypes.

148 of the JCI, Riggle et al. explored the brain vasculature from 34 children who died from HCM or other

149 The transcriptome of tumor blood vasculature from human invasive bladder carcinoma (I-BLC

150 f PCV by quantitatively evaluating choroidal vasculature from the entire fundus using ultra-widefield

151 ulvin in adult mice does not disrupt retinal vasculature, function, or morphology.

152 ne can extract over 20 features from retinal vasculature fundus images.

153 e correlated with a loss of pulmonary venous vasculature, greater pectoralis muscle sarcopenia, and l

154 mensional structures in skin such as nerves, vasculature, hair follicles, and sebaceous glands.

155 The vasculature has a critical role during early stages of d

156 hat forms fibrillary deposits in aging human vasculature, has not been heavily investigated.

157 gical or functional defects in the lymphatic vasculature have now been uncovered in several pathologi

158 t suited for lipid storage (e.g., the liver, vasculature, heart, and pancreatic beta-cells).

159 elial-selective transfection of the cerebral vasculature (i.e., "sonoselective" transfection), withou

160 Currently, a volumetric vasculature imaging method with sub-capillary spatial re

161 e mechanisms to disrupt migration toward the vasculature, impairing proplatelet release and causing m

162 f intracranial aneurysms and the surrounding vasculature in a location specific manner.

163 ntifiably facilitate development of perfused vasculature in a microfluidic system.

164 we analysed brain-wide rearrangements of the vasculature in animal models of congenital deafness and

165 based therapy strategies to replace coronary vasculature in damaged hearts.

166 etal muscle cells instead of contributing to vasculature in etv2-deficient embryos.

167 ame intralesional tortuous patterns, whereas vasculature in eyes with PAM was similar to normal conju

168 ional views about the roles of the lymphatic vasculature in health and disease.

169 of cartilage to bone transdifferentiation or vasculature in human-relevant TMJ OA large animal models

170 (OCTA) allows for noninvasive imaging of the vasculature in melanocytic lesions of the conjunctiva an

171 FSH is expressed predominantly in the vasculature in patterns that do not significantly overla

172 Understanding the structure and function of vasculature in the brain requires us to monitor distribu

173 iciency causes hemorrhages from the maternal vasculature in the junctional and/or labyrinthine zones

174 und no age-related changes in the density of vasculature in the peduncle from P5 to P30.

175 Abnormal vasculature in tumors leads to poor tissue perfusion and

176 developmental precursor of the adult retinal vasculature in zebrafish.

177 strate the feasibility of including perfused vasculature, including ISEMFs, as critical components of

178 In the heart and vasculature, inflammatory macrophages also enhance tissu

179 ever, large AVMs developed in the peripheral vasculature intimately associated with the pelvic cartil

180 lial cells (HIECs), and incorporate perfused vasculature into a gut-on-a-chip (GOC) model that includ

181 (sLeX) regulates T cell trafficking from the vasculature into skin and sites of inflammation, thereby

182 the metastatic process, cells migrate to the vasculature, intravasate, extravasate, and establish met

183 anism that ensures proper and timely hyaloid vasculature invasion of the OF in order to facilitate av

184 The cerebral vasculature is a dense network of arteries, capillaries,

185 ly, we determined that OF associated hyaloid vasculature is a source of mmp2, mmp14a and mmp14b expre

186 The lymphatic vasculature is a unidirectional conduit that returns fil

187 Lymphatic vasculature is an integral part of digestive, immune and

188 ry interstitial macrophages around pulmonary vasculature is associated with increased muscularization

189 occluded for the first and the whole tumour vasculature is destroyed for the latter.

190 Contractile activity in the lymphatic vasculature is essential for maintaining fluid balance w

191 The lymphatic vasculature is involved in the pathogenesis of acute car

192 angiogenic cues in repair of the established vasculature is largely unknown.

193 but how ENG functions to regulate the adult vasculature is not understood.

194 and physiologic role of small intestine (SI) vasculature is poorly studied.

195 immunity along with its associated lymphatic vasculatures is widely discussed recently.

196 ent of single blood cells within the retinal vasculature (Joseph et al. 2019) using adaptive optics o

197 n various organ systems including the heart, vasculature, kidney, and central nervous system (CNS).

198 ise the integrity of the BBB, resulting in a vasculature known as the blood-tumour barrier (BTB), whi

199 's disease, amyloid deposits along the brain vasculature lead to a condition known as cerebral amyloi

200 Disorganized vessels in the tumor vasculature lead to impaired perfusion, resulting in red

201 results provide new evidence that the brain vasculature, like that of the yolk sac and the eye chori

202 physiological microenvironment supplied by a vasculature-like microfluidic perfusion.

203 The brain vasculature maintains brain homeostasis by tightly regul

204 CS includes dilated vasculature, marked cardiac hypertrophy, and other cardi

205 uman TMJ cells exhibited marked increased in vasculature markers relative to control 293T cells.

206 However, pathological changes in the vasculature may be present that prevent accurate reconst

207 ds to severely stunted growth of the retinal vasculature, mildly stunted growth of the cerebellar vas

208 To carry out this function, the blood vasculature must deliver oxygen and nutrients and recrui

209 MDA-MB-468), and the evolution of functional vasculature "normalization" was resolved macroscopically

210 Sustained, indolent immune injury of the vasculature of a heart transplant limits long-term graft

211 hotopic growth, VEGF-A expression, and tumor vasculature of both TNBC and HER2-positive trastuzumab-r

212 ing a novel model system: the extracorporeal vasculature of Botryllus schlosseri, in which the disrup

213 mmon forms of localized amyloid found in the vasculature of individuals older than 50 years.

214 or functional changes in the glial cells or vasculature of Jedi-1 knockout mice.

215 Deletion of Yap and Taz in the lymphatic vasculature of mouse embryos did not affect the formatio

216 cer tumor blood vasculature with tumor blood vasculature of other solid cancers, which correlated wit

217 blood cells that accumulate in the cerebral vasculature of patients has led to the belief that these

218 CEPR1 is expressed throughout the vasculature of reproductive organs, including in the cha

219 eous fissures and cisterns to the underlying vasculature of the posterior pole was visible on en face

220 tly decreased expression of claudin-5 in the vasculature of various tissues, including brain and lung

221 Endothelial cells (ECs) lining the vasculature of vertebrates respond to low oxygen (hypoxi

222 of Medin also develop in the aorta and brain vasculature of wild-type mice in an age-dependent manner

223 ave similar retinal thickness but less dense vasculature on OCTA compared to age and race-matched con

224 hy revealed dilated hyperpermeable choroidal vasculature on the nasal side of the fovea in the early

225 l sector of the optic disc, remnant of fetal vasculature on the optic disc (Bergmeister's papilla).

226 and neurotransmitters that reach it via the vasculature or skin nerves, and/or are generated intracu

227 phological assessment showed decreased renal vasculature, particularly of the glomerular capillary kn

228 anscription factor Cucumis sativus Irregular Vasculature Patterning (CsIVP) was highly expressed in c

229 rom synthetic, mouse-brain, lung, and fundus vasculature phantoms were used for training and testing.

230 chniques which reveal abnormalities of tumor vasculature play significant roles in both mechanistic a

231 Thus, CsIVP is a novel vasculature regulator functioning in CsYAB5-mediated org

232 HSPCs since their homing to the bone marrow vasculatures remained intact.

233 The vasculature represents a highly plastic compartment, cap

234 healthy and pathological aging of the human vasculature represents an unresolved experimental challe

235 eady state, classical monocytes give rise to vasculature-resident cells that patrol the luminal side

236 We report how ISEMF and EC-derived vasculature responds to physiologic parameters such as o

237 ysaccharide (LPS) revealed that the cerebral vasculature responds within minutes to acute systemic in

238 ifically in mouse ECs, providing a model for vasculature-restricted respiratory deficiency.

239 BMP4-binding capacity disrupted the retinal vasculature, resulting in poorly formed networks, especi

240 rich ciliary zonules that originate from the vasculature-rich ciliary body and extend along the surfa

241 ar development and our understanding of this vasculature's role in pathophysiological conditions has

242 of the CT angiography examinations included vasculature segmentation and the creation of maximum int

243 induces constitutive long hypocotyls, while vasculature-specific expression of PIF4 has no effect on

244 n essential physiological measure reflecting vasculature status and tissue viability of the skeletal

245 In addition to revealing 15 central vasculature stenoses, ferumoxytol-enhanced MR angiograph

246 ting to the lung periphery, the avoidance of vasculature structures when performing diagnostic biopsi

247 ally identifies key features of the cerebral vasculature such as branching of the internal intracrani

248 ace expression in the lung, small bowel, and vasculature, suggesting abdominal viscera may be suscept

249 n of multiple Notch1 target genes in hepatic vasculature, suggesting constitutive functional importan

250 of oscillatory MGP expression in developing vasculature supported the in vitro findings.

251 Stroke causes remodeling of vasculature surrounding the infarct, but whether and how

252 Stroke causes remodeling of vasculature surrounding the lesion, but whether and how

253 imited to the central 10 cm of the pulmonary vasculature (termed series 2).

254 e associated with alterations in the retinal vasculature that are possibly preceded by undetected cha

255 ertension (PAH) is a severe disorder of lung vasculature that causes right heart failure.

256 , a crucial connection between the heart and vasculature that develops while circulation is under way

257 erturbations in the heart and the peripheral vasculature that differ in physiology and clinical manif

258 ue pathology, including abnormalities in the vasculature that foster cancer progression(5,6); however

259 ary hypertension, a disease of the pulmonary vasculature that results in right heart failure and deat

260 interplay between the liver and the systemic vasculature that results in the development of the extra

261 ies is a critical attribute of the lymphatic vasculature, the barrier function of collecting lymphati

262 of the alterations in cerebral and systemic vasculature, the heart, and hemostasis that occur in Alz

263 le is known about their interaction with the vasculature; therefore, this study assessed the effects

264 stasis and initiating adaptive growth of new vasculature through angiogenesis.

265 We have designed a xenograft model of human vasculature to address this issue.

266 Recent studies have suggested hyaloid vasculature to be involved in OF fusion.

267 dly rectifying K(+) (K(IR) ) channels on the vasculature to elicit an increase in blood flow.

268 These age-associated changes prime the vasculature to exacerbate atherogenesis upon acute hyper

269 haustoria and build a connection to the host vasculature to exhaust water, solutes and carbohydrates.

270 x differences in the ability of the cerebral vasculature to increase its blood flow (cerebrovascular

271 pport a mechanism by which microglia use the vasculature to migrate within the developing brain paren

272 ume, mean vessel diameter, and distance from vasculature to necrotic tissue.

273 n the angiogenesis and ingrowth of recipient vasculature to perfuse tissues, preventing analysis of b

274 How HSPCs transmigrate from the vasculature to the niches is unclear.

275 The precise contribution of the lymph node vasculature to the regulation of this process remains un

276 al derangement that ultimately affects renal vasculature tone.

277 Endothelial cells that line the vasculature use molecular mechanosensors to directly det

278 a full retina slab based on the full retina vasculature using OCT angiograms.

279 lower temporal and inferior parafoveal deep vasculature values than NAION eyes (P = .007 and .03, re

280 PSMA expression in the tumor vasculature was assessed and staining intensity was scor

281 carcinoma (I-BLCA) and normal bladder tissue vasculature was compared using differential expression a

282 investigated and MN penetration into luminal vasculature was confirmed in vivo.

283 hogenic crosstalk between the epithelium and vasculature, we introduce a 3D microfluidic platform tha

284 n between pax2a loss of function and hyaloid vasculature, we observed significant reduction of talin1

285 onocytes (PMo) behave as housekeepers of the vasculature, we tested whether PMo protect microvessels

286 tions with histological assessments of tumor vasculature were noted (Spearman R > 0.70) in pre-clinic

287 sion-fixed material, details of the cochlear vasculature were seen throughout the cochlea.

288 e homocysteine and inducing defects in optic vasculature, which result in aneurysms and eye hemorrhag

289 th PDR RUNX1 expression was increased in the vasculature, while in human retinal microvascular endoth

290 l human TMJ tissues also exhibited increased vasculature, while isolated diseased human TMJ cells exh

291 sms underpinning the anastomosis of the host vasculature with blood vessels generated by DPSCs (a mod

292 ondrocytes undergo apoptosis, while invading vasculature with osteoprogenitors replace cartilage with

293 TGFbeta1 expression and abnormally-patterned vasculature with severe malformations in the area of pho

294 The liver connects the intestinal portal vasculature with the general circulation, using a divers

295 for processing arterial and venous cerebral vasculature with the network was less than 90 seconds.

296 dentified between bladder cancer tumor blood vasculature with tumor blood vasculature of other solid

297 ng Jagged production results in pathological vasculatures with thinner and more abundant vessels, whi

298 obeads formed functional connections to host vasculature within 3 days and exhibited extensive, matur

299 In order to visualize retinal vasculature without the need for FA and in a cost-effect

300 Understanding the way its blood vasculature works is key.