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4 n atom replacing a sulfur atom), blocked the vasodilatory action of H2O2 on resistance vessels and re
6 th rats fed a LFD, HFD feeding abolished the vasodilatory actions of globular adiponectin (gAd) and i
7 microvascular endothelial cells (HMVEC) and vasodilatory actions on bovine coronary arteries and rec
9 pressure and adverse events consistent with vasodilatory activity of AKB-9778 emerged at doses of 22
10 ) and thereby provide a basis for the graded vasodilatory activity that is inversely proportional to
15 suggests that other factors may explain the vasodilatory adaptations that occur following repeated R
16 NO, (localization, diffusiveness, half-life, vasodilatory affects) have supported its potential role
22 generating angiotensin-(1-7), which induces vasodilatory and antiproliferative actions in the cardio
23 I(2) (prostacyclin) is a lipid mediator with vasodilatory and antithrombotic effects used in the trea
24 time course and degree to which mechanical, vasodilatory and cardiac mechanisms contribute to the in
26 rteries, and greater vasoreactivity (greater vasodilatory and constrictor responses) than age-matched
27 = 0.02) and dramatically reduced the overall vasodilatory and hyperaemic response (area under the cur
28 ter VEGFR2 activation, the mast cell-derived vasodilatory and inflammatory mediators may contribute m
30 roperties of angiotensin II (Ang II) and the vasodilatory and natriuretic properties of bradykinin an
31 kt and eNOS contributes to some of the acute vasodilatory and neuroprotective effects of thyroid horm
32 rease the availability of peptides that have vasodilatory and other vascular effects; they also inhib
35 ictive) and atrial natriuretic peptide (ANP; vasodilatory) antagonize the biological actions of each
37 cytochrome P450 (CYP) epoxygenases, possess vasodilatory, antiinflammatory, and fibrinolytic propert
41 ROLS: 3.73 +/- 0.71 mm, p<0.05), had greater vasodilatory (BAFMD%: Athletes: 8.21 +/- 1.78 vs. CONTRO
42 Of note was an apparent 10-fold increase in vasodilatory bradykinin that reversed after drug infusio
43 pacity on low-density lipoproteins), and HDL vasodilatory capacity (HDL ability to induce the release
44 paraoxonase-1 arylesterase activity, and HDL vasodilatory capacity (relative to control, P=0.039, P=0
47 vascular dysfunction resulting in diminished vasodilatory capacity and tissue hypoperfusion is associ
48 ly treadmill exercise would improve the poor vasodilatory capacity of collateral arteries isolated fr
49 rcise training improves endothelium-mediated vasodilatory capacity of hindlimb collateral arteries, a
51 he resistive reserve ratio, a measure of the vasodilatory capacity of the microcirculation and calcul
57 r an upstream resistance site is under tonic vasodilatory control or a downstream site is under vasoc
58 ion neurons of birds use VIP and NO to exert vasodilatory control over blood flow to and within the a
62 fferences in skeletal muscle metabolism, not vasodilatory dynamics, must account for the augmented gl
63 n restored age-related endothelial-dependent vasodilatory dysfunction and increased the phosphorylate
66 Albumin-mediated S-nitrosylation and its vasodilatory effect directly depend on the concentration
67 on, an NO-trapping agent, reversed the basal vasodilatory effect of ACEI in the pulmonary vasculature
69 dothelial nitric oxide synthase and that the vasodilatory effect of endothelial nitric oxide synthase
71 art disease is limited because of the potent vasodilatory effect that causes hypotension, and other s
75 ne whether such effects may be attributed to vasodilatory effects in the uteroplacental circulation.
76 ising cAMP content, have acute inotropic and vasodilatory effects in treating congestive heart failur
78 We investigated the hemodynamic and coronary vasodilatory effects of CGS-21680, a potent selective ad
79 ene name EDNRB)], the receptor mediating the vasodilatory effects of endothelin-1 (ET-1) is induced b
80 ence of aging and the menopause on the acute vasodilatory effects of estrogen using ex vivo human and
82 ing lung pathology consistent with competing vasodilatory effects on the normal and abnormal areas th
83 s often limited by the appearance of adverse vasodilatory effects such as headache or peripheral edem
84 DPPH, FRAP and ABTS assays and the in vitro vasodilatory effects were assessed using norepinephrine
87 serum sodium levels, and had more pronounced vasodilatory effects, compared with LeTx, as reflected b
88 and symptomatic improvement through balanced vasodilatory effects, neurohormonal suppression and enha
91 ,8,11-trienoic acid (14,15-EET) is a labile, vasodilatory eicosanoid generated from arachidonic acid
92 dothelial 15-lipoxygenase (15-LO) to several vasodilatory eicosanoids such as 11,12,15-trihydroxyeico
94 sent in rodents, as a sole neighbor to human vasodilatory endothelial nitric oxide (NO) signaling.
95 eurons as their main cellular source and the vasodilatory EP2 and EP4 receptors as their main targets
96 yramidal cells as their principal source and vasodilatory EP2 and EP4 receptors as their targets.
97 E) and neutral endopeptidase, which degrades vasodilatory factors (eg, ADM) and natriuretic peptides.
100 Arterial blood pressure is controlled by vasodilatory factors such as nitric oxide (NO) that are
101 l view is that neurons or astrocytes release vasodilatory factors that act directly on smooth muscle
102 protein expression and endothelial-dependent vasodilatory function exhibited a progressive, age-relat
103 ginine supplementation to completely restore vasodilatory function may be attributable to the down-re
105 ce, respectively) with regard to endothelial vasodilatory function, endothelial progenitor cell (EPC)
109 gic processes in which cardiac inotropic and vasodilatory functions are linked to specific aspects of
110 erein to modulate the vascular signaling and vasodilatory functions of nitric oxide (NO) during acute
111 tent oxidant) to generate carbon monoxide (a vasodilatory gas that has anti-inflammatory properties),
112 enzyme that degrades heme to generate CO (a vasodilatory gas), iron, and the potent antioxidant bili
113 chamber (8 degrees C to 10 degrees C) and a vasodilatory heat chamber (40 degrees C to 42 degrees C)
114 wice that of control fetuses at rest, during vasodilatory hyperaemia, and during hyperaemia plus incr
115 domized patients aged 65 years or older with vasodilatory hypotension (assessed by treating clinician
116 65 years or older receiving vasopressors for vasodilatory hypotension, permissive hypotension compare
120 alatine ganglia, the source of nitroxidergic vasodilatory innervation of cerebral blood vessels.
124 O(2) demand is thought to be satisfied by a vasodilatory mechanism that results in increased blood a
126 sympathetic contractile agents and unaltered vasodilatory mechanisms may provide a means for maintena
127 agonist of the thromboxane receptor, whereas vasodilatory mechanisms of CO relied on the activation o
131 nduced mast cell-derived proinflammatory and vasodilatory mediator production in a VDR-dependent mann
132 does not restore HPV, indicating that other vasodilatory mediators besides NO also influence HPV in
134 ing perfusion to the small intestine via the vasodilatory molecule endothelial nitric oxide synthase
137 eoxy)-state subserves the release from Hb of vasodilatory nitric oxide (NO) bioactivity, it has not y
138 Because of its capacity to potentiate the vasodilatory NO/cyclic guanylate monophosphate signaling
139 egatory, antiadhesive, antiinflammatory, and vasodilatory omega-3 (n-3) fatty acids (DHA and EPA) are
141 This effect is independent of any other vasodilatory or endothelial effects and is apparently ex
143 tion and K(ATP) channel opening is the major vasodilatory pathway for sildenafil in retinal arteriole
148 , when negated, allows for the expression of vasodilatory pathways which are masked by the primary ox
149 ular [Ca(2+)] regulate endothelium-dependent vasodilatory pathways, the molecular identities of the i
155 disease by using systemic overproduction of vasodilatory peptides, such as atrial natriuretic peptid
156 uces vasoconstriction through suppression of vasodilatory peptides, such as glucagon, or through a lo
158 P-loading greatly improved HDL signaling and vasodilatory potential in pre-contracted arteries and co
160 Inhibition of eNOS reduces synthesis of its vasodilatory product, nitric oxide, leading to arterial
161 have several roles in skin-e.g., pro-edema, vasodilatory, proinflammatory, and pruritogenic-melatoni
162 S-nitrosation of Hb (SNO-Hb) may confer vasodilatory properties by allowing release of NO during
164 fat diet combining the anti-inflammatory and vasodilatory properties of eicosapentaenoic acid (EPA; f
165 enalaprilat, verapamil, and caffeine on the vasodilatory properties of the adenosine A(2A)-receptor
166 erent assays to evaluate the antioxidant and vasodilatory properties of three typical food products f
167 ts of cytochrome P450 epoxygenases that have vasodilatory properties similar to that of endothelium-d
169 omeric epoxyeicosatrienoic acids have potent vasodilatory properties while 20-hydroxyeicosatetraenoic
172 nner, was associated with an increase of the vasodilatory prostaglandin (PG) D2 in plasma and could b
175 e positioning, inhaled nitric oxide, inhaled vasodilatory prostaglandins, and extracorporeal membrane
176 ed rats was associated with incorporation of vasodilatory prostanoids in the renal-cell membrane and
180 y, severe coronary artery disease, decreased vasodilatory reserve of epicardial and resistance arteri
182 n consumed), peak VO2, total work performed, vasodilatory reserve, forearm mitochondrial oxidative fu
184 hibition during exercise caused an immediate vasodilatory response (increase in Con(T) and Con(L) and
185 3] sigmoidal dose-response curve indicated a vasodilatory response as the concentration of the antago
186 s are obligatory to observe the normal local vasodilatory response from rest to SS hypoxia; (2) NO re
187 d to FMD but, by age ~65 years, the arterial vasodilatory response has begun to uncouple from the WSR
188 o cardiac myocytes as well as modulating the vasodilatory response mediated by endothelial nitric oxi
189 es can damage the endothelium and impair the vasodilatory response of arteries; however, there are no
191 , there was no age-related difference in the vasodilatory response to acetylcholine among the enduran
192 d hypercoagulability, and restoration of the vasodilatory response to acetylcholine to levels compara
194 rats exposed to CIH exhibited an attenuated vasodilatory response to ACh and hyperresponse to Mtx co
196 strate that K(IR) channels mediate the rapid vasodilatory response to an increase in exercise intensi
198 xation is increased; (4) L-NAME suppressible vasodilatory response to ET is abolished; (5) there is n
200 e observed impairments in ACh responses, the vasodilatory response to exogenous ATP is not reduced wi
201 n the Middle Aged and Old SMFAs restored the vasodilatory response to flow (Middle Aged + Adropin: 59
203 y is depleted in banked blood, impairing the vasodilatory response to hypoxia, and they suggest that
209 52.3 +/- 1.1% (P < 0.001) and inhibited the vasodilatory response to NF023 (50 mum, 7.9 +/- 2.0%; P
211 e to the upright-seated posture augments the vasodilatory response to PLM in the young, with no effec
218 nist ACh, whereas there was no change in the vasodilatory response to sodium nitroprusside, an endoth
222 ogs produced vasodilation, whereas a similar vasodilatory response was observed during exercise in CH
223 essure and both the immediate and peak rapid vasodilatory response, such that the responses increased
224 e vascular endothelial nitric oxide synthase vasodilatory response, which is a common potential site
232 nize the effects of endothelin-1, it induced vasodilatory responses leading to a significant improvem
235 lower apoA-I levels also displayed impaired vasodilatory responses to acetylcholine (mean +/- SEM, 1
236 explains how vascular XO activity diminishes vasodilatory responses to acetylcholine in hypercholeste
238 17-ODYA interventions, respectively) mediate vasodilatory responses to ACh but not to KCl, and that v
241 B) receptor mediated, nitric oxide dependent vasodilatory responses to ET-1 compared with controls an
242 VC dose-response curves demonstrated reduced vasodilatory responses to ET-1 in lean AE-PCOS (logED(50
243 ased ipsilateral, but not contralateral, UBF vasodilatory responses to exogenous E2beta by approximat
244 d whites exhibited comparable myocardial and vasodilatory responses to heat stress, but blacks exhibi
245 blocker, BaCl(2) (30 micromol/L), inhibited vasodilatory responses to KCl and bradykinin but not to
246 lts indicate that relaxin mediates the renal vasodilatory responses to pregnancy and thus may be impo
249 pothesis that muscle fatigue would attenuate vasodilatory responsiveness throughout the resistance ne
250 2) the COX pathway does not appear to have a vasodilatory role in cutaneous reactive hyperaemia.
251 e blood-pressure-lowering effects of the new vasodilatory, selective endothelin type A antagonist, da
253 the well-described vasopressin deficiency in vasodilatory septic shock, these studies indicate that d
263 device (n=23) were evaluated for post-bypass vasodilatory shock requiring catecholamine pressors, and
264 at our institution have studied a variety of vasodilatory shock states that are characterized by vaso
267 ly increased blood pressure in patients with vasodilatory shock that did not respond to high doses of
270 sin plasma levels are inappropriately low in vasodilatory shock, most likely because of impaired baro
271 y of vasopressin has been found in prolonged vasodilatory shock, such as is seen in severe sepsis.
276 GS5 may balance vascular tone by attenuating vasodilatory signaling in vivo in opposition to RGS2, an
278 egulate blood pressure by releasing ATP as a vasodilatory signaling molecule in response to the incre
279 (.)); however, the effects of aldosterone on vasodilatory signaling pathways in vascular smooth muscl
281 sient receptor vanilloid 4 (TRPV4) channel's vasodilatory signaling using mathematical modeling.
282 ung adults, increasing endothelium-dependent vasodilatory signalling during mild exercise augments sy
284 onstrate that specific endothelium-dependent vasodilatory signalling is amplified in the vasculature
285 ns selectively amplify endothelium-dependent vasodilatory signalling via activation of K(IR) channels
286 hesis that stimulating endothelium-dependent vasodilatory signalling will enhance the ability of cont
288 port the concept that EC Kir2 channels boost vasodilatory signals that are generated by Ca(2+) -depen
289 an elicit physiologically relevant spread of vasodilatory signals within the highly interconnected br
291 , and recently we observed that a variety of vasodilatory states are characterized by vasopressin def
293 trate were measured before and after a renal vasodilatory stimulus of a mixed amino acid intravenous
294 vel-dependent (BOLD) MRI in conjunction with vasodilatory stress to index the ability to augment intr
297 yte Ca2+ elevations can lead to secretion of vasodilatory substances from perivascular astrocyte endf
300 scular model, we hypothesized that cutaneous vasodilatory (VD) function elicited by localized heating