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1 sequestration and desensitization of the V2 vasopressin receptor.
2 lial cells expressing the Galphas-coupled V2 vasopressin receptor.
3 en-transmembrane receptor, the Gs-coupled V2 vasopressin receptor.
4 s in the neural distribution of oxytocin and vasopressin receptors.
5 modulatory functions of ILG on dopamine and vasopressin receptors.
6 zation of the parathyroid hormone and type 2 vasopressin receptors.
7 properties on the insect and human oxytocin/vasopressin receptors.
8 n receptor is only 30 to 50% homologous with vasopressin receptors.
9 llent selectivity against the human arginine vasopressin receptors.
10 nt series of soluble receptor analogs, named vasopressin receptor 1 elements on a soluble scaffold (V
11 nsitization was investigated by studying two vasopressin receptors 14 and 27 amino acids shorter than
15 ingle 20 mg intravenous dose of the arginine vasopressin receptor 1A (V1a) antagonist, RG7713, on exp
16 ats RS1, RS3 and AVR in the AVPR1A (arginine vasopressin receptor 1a) gene and STin2 in the SLC6A4 (s
18 le-nucleotide polymorphism near the arginine vasopressin receptor 1b gene is associated with serious
19 e-nucleotide polymorphism (near the arginine vasopressin receptor 1b gene) was significantly associat
20 n of STAT3 in renal cystic cells depended on vasopressin receptor 2 (V2R) signaling, which increased
21 ncentration mechanism by modulating arginine vasopressin receptor 2 and AQP2 expression in the inner
26 ture-function relationship studies of the V2 vasopressin receptor, a prototypical G(s)-coupled recept
27 mutations in rhodopsin, cone opsins, the V2 vasopressin receptor, ACTH receptor, and calcium-sensing
28 icate that in cultured cortical neurons, V1a vasopressin receptor activation leads to induction of th
29 ent was activated by phospholipase C-coupled vasopressin receptor activation or by the diacylglycerol
30 from our laboratory has demonstrated that V1 vasopressin receptor agonist (V1 agonist) induces a comp
31 treatment of mpkCCD14 cells with the type 2 vasopressin receptor agonist dDAVP increased mRNA and pr
32 sure of cortical neurons to the selective V1 vasopressin receptor agonist, [Phe2,Orn8]-vasotocin, (V1
33 and-induced endocytosis of two GPCRs: the V2 vasopressin receptor and beta-2 adrenergic receptor, wit
34 from receptor to receptor (400% with type 2 vasopressin receptor and only 30% with M2R), expression
35 ing increased male expression of angiotensin-vasopressin receptor and prolactin receptor, decreased 5
36 ic release of vasopressin and the cloning of vasopressin receptors and of vasopressin-regulated water
37 ectivity versus the related V1a, V1b, and V2 vasopressin receptors and short half-life: agonists 31 (
38 erenol (luteinizing hormone receptor, type 2 vasopressin receptor, and types 1 and 2 beta-adrenergic
39 In patients with advanced heart failure, vasopressin receptor antagonism with conivaptan resulted
40 erapy, infusion of hypertonic saline, use of vasopressin receptor antagonist (vaptans), or use of ren
42 receptor antagonist), but not by an oxytocin/vasopressin receptor antagonist or a micro-opioid recept
44 on of [3H]IP1 was blocked by a selective V1a vasopressin receptor antagonist, (Phenylac1, D-Tyr(Me)2,
45 treatment with conivaptan, a dual V(1a)/V(2) vasopressin receptor antagonist, at a single intravenous
46 ct of oral administration of a nonpeptide V2 vasopressin receptor antagonist, OPC 31260, was therefor
50 n are identical, but the human V(1)- or V(2)-vasopressin receptors are approximately 80% homologous w
52 Examination of the structure of [Arg(8)]-vasopressin receptors (AVPRs) and oxytocin receptors (OT
54 animals, while antagonists of the opioid and vasopressin receptors blocked hindlimb postural asymmetr
55 ermitted an alpha s-coupled receptor (the V2 vasopressin receptor but not the beta 2-adrenergic recep
57 alpha q-coupled receptors (bombesin and V1a vasopressin receptors but not the oxytocin receptor) to
58 observed with other receptors such as the V2 vasopressin receptor, but did couple with the clathrin a
59 a fetus is not mediated by stimulation of V1-vasopressin receptors, but is dependent on alpha-adrener
60 t that occupation of a small fraction of V1a vasopressin receptors by AVP results in stimulation of p
61 ion) by vasopressin-induced activation of V2 vasopressin receptors co-expressed at similar levels.
64 The extracellular portion of the human V2 vasopressin receptor contains one site susceptible to N-
65 e two classes of receptors (beta(2)AR and V2 vasopressin receptors), demonstrate reversal of the patt
66 Among monogamous prairie voles, levels of vasopressin receptor (encoded by the gene avpr1a) in bra
68 d species-specific patterns of oxytocin- and vasopressin-receptor expression in the brain that appear
71 ule agonists and antagonists of the oxytocin/vasopressin receptor family and identified two, SR49059
75 t changes in the regulation of oxytocin- and vasopressin-receptor gene expression underlie these spec
76 expression variations of the oxytocin and/or vasopressin receptor genes OXTR and AVPR1A, respectively
77 r these conditions, the expression of OT and vasopressin receptor genes, as well as marker genes of s
79 has a high degree of selectivity toward the vasopressin receptors, >10,000 for hV1a/hV1b and approxi
81 >31000-fold selectivity over all three human vasopressin receptors hV1aR, hV2R, and hV1bR, with no si
83 The antagonist bound specifically to the V1a vasopressin receptor in crude rat liver membranes with a
84 ansduction mechanism associated with the V1a vasopressin receptor in enriched cultures of cortical ne
85 e value in testing medications targeting the vasopressin receptor in high stress, alcohol-dependent p
86 demonstrate an effector mechanism for the V1 vasopressin receptor in the cerebral cortex and provide
88 s aggression by increasing the number of V1a vasopressin receptors in the anterior hypothalamus (AH).
89 selected for greater potential benefit from vasopressin receptor inhibition, tolvaptan was not assoc
90 phatidylinositol hydrolysis), whereas the V2 vasopressin receptor is selectively coupled to Gs (bioch
91 of this approach, a series of nine mutant V2 vasopressin receptors known to be responsible for X-link
92 93 cells, stimulation of the beta(2)AR or V2 vasopressin receptor leads, respectively, to transient o
94 s that is initiated by G-protein-coupled V1a vasopressin receptor-mediated cytoplasmic and nuclear Ca
95 n important role for development of oxytocin/vasopressin receptor modulators that would enable clear
96 ace levels of two folding-defective human V2-vasopressin receptor mutants, which were susceptible to
97 hat the naturally occurring loss of function vasopressin receptor mutation R137H, which is associated
98 contractile responses suggests increases in vasopressin receptor number, affinity, and/or efficiency
99 nM, selectivity ratios versus related human vasopressin receptors of >2000, IC50 at hV1aR > 500 nM,
100 thway for an orphan GPCR referred to here as vasopressin receptor-related receptor 1 (VRR1) by genera
101 flammatory genes and disappearance of the V2 vasopressin receptor, resulting in loss of AQP2 (confirm
102 has made possible the selective blockade of vasopressin receptor subtypes for therapeutic purposes.
104 thetic phosphopeptide mimicking the human V2 vasopressin receptor tail that binds and functionally ac
106 eptors including CXCR4, mu-Opioid and type-2 Vasopressin receptors that selectively control the activ
107 opressin-regulated water channel) and the V2 vasopressin receptor, that are important to regulated wa
111 tide derived from the C terminus of the V(2) vasopressin receptor (V(2)Rpp) or the corresponding unph
113 ropeptide vasopressin and are prevented by a vasopressin receptor [V1a receptor (V1aR)] antagonist in
114 determine the downstream consequences of V1a vasopressin receptor (V1aR) activation of Ca2+ signaling
115 VPA exposure downregulated prefrontal cortex vasopressin receptor (V1aR) and methyl CpG-binding prote
116 ure and functional expression of a human V1a vasopressin receptor (V1aR) cDNA isolated from human liv
119 nvestigate whether individual differences in vasopressin receptor (V1aR) or oxytocin receptor (OTR) r
120 recently, we have detected mRNA for the V1a vasopressin receptors (V1aRs) in cultured cortical neuro
122 nction mutations in the gene encoding the V2 vasopressin receptor (V2R) cause nephrogenic syndrome of
123 tissues through the inhibition of the type-2 vasopressin receptor (V2R) constitutes a validated strat
125 e caused by inactivating mutations in the V2 vasopressin receptor (V2R) gene that result in the loss
129 entify molecules that might contribute to V2 vasopressin receptor (V2R) trafficking or signaling, we
130 les in the regulation and function of the V2 vasopressin receptor (V2R), a G protein-coupled receptor
133 itineraries of wild type (WT) and mutant V2 vasopressin receptors (V2Rs) in polarized Madin-Darby ca
134 y (both of which are related to dopamine and vasopressin receptors), we investigated the binding affi
137 nant for nephrogenic diabetes insipidus, the vasopressin receptor with a substitution at the DRY moti