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1 tion in isolated arteries and oppose certain vasorelaxants.
2 ntify new chemical spaces for KCNQ-dependent vasorelaxants.
3  interplay of endothelin-1 with the putative vasorelaxant 2-arachidonoyl glycerol, an endogenous cann
4 ), the enzyme catalyzing biosynthesis of the vasorelaxant acetylcholine (ACh), regulate vasodilation
5 (ChAT), which catalyzes the synthesis of the vasorelaxant acetylcholine, relay neural signals.
6 53 does not possess the direct, IM-sensitive vasorelaxant action of troglitazone.
7 ivity relationships for the antiischemic and vasorelaxant activities of KATP openers are distinct.
8 o Allium extracts, including hypotensive and vasorelaxant activities.
9 are favored in the oxygenated structure, and vasorelaxant activity is "linked" to deoxygenation, as i
10 culation, and NPR-C activation underlies the vasorelaxant activity of this peptide.
11 d cardiac tissues, devoid of chronotropy and vasorelaxant activity.
12                                          The vasorelaxant and anti-mitogenic activities of the atrial
13 ies as a memory aid, analgesic, spasmolytic, vasorelaxant and antihypertensive, with recent preclinic
14 support that there is no correlation between vasorelaxant and cardioprotective potencies of KATP open
15 t in the kidney, where it exerts significant vasorelaxant and neuromodulatory effects.
16                        Hydrogen sulfide is a vasorelaxant and proangiogenic gas with therapeutic pote
17                                          The vasorelaxant and protective activity of CNP and cANF(4-2
18 , for a variety of indications, including as vasorelaxants and antispasmodics.
19 the normal response to endothelium-dependent vasorelaxants and myocardial perfusion in response to FG
20 asma levels of adrenomedullin (AM), a potent vasorelaxant, are increased in septic shock and possibly
21 anandamide has recently been identified as a vasorelaxant but the underlying mechanisms are controver
22 mparable (ED(50) 1.7 microM) to 14,15-EET as vasorelaxants but were approximately 10-35 times less po
23  and direct intracavernosal injection of the vasorelaxant drug papaverine cause rapid increases in ph
24            Papaverine is typically used as a vasorelaxant due to its ability to inhibit phosphodieste
25     The alpha-tocopherol moiety alone had no vasorelaxant effect at concentrations up to 300 micromol
26                           NPR-A mediates the vasorelaxant effect of ANP in pulmonary vasculature.
27                                          The vasorelaxant effect of LPS was blocked by L-NIL.
28 domethacin (IM; 10 micromol/l; n = 12), this vasorelaxant effect of troglitazone was abolished (P < 0
29 er a molecular mechanism underlying rosemary vasorelaxant effects and identify new chemical spaces fo
30 on-dependent (1-30 microM) inhibition of the vasorelaxant effects of abn-cbd and anandamide.
31 r-853 were not observed, indicating that the vasorelaxant effects of cGKI are not through dephosphory
32                                          The vasorelaxant effects of the endothelium-derived relaxing
33 lates flow by releasing endothelium-mediated vasorelaxant factors such as NO.
34 l dysfunction or drugs that are large-artery vasorelaxants may be effective in reducing large-artery
35 , indicating increased release of the potent vasorelaxant nitric oxide.
36 more potent, respectively, than 14,15-EET as vasorelaxants; on the other hand, their ability to block
37  of 27 results from a combination of reduced vasorelaxant potency and enhanced cardioprotective poten
38 andidate to investigate the role of residual vasorelaxant potency of 2 toward its cardioprotective ac
39 hemic myocardium is achieved by reduction of vasorelaxant potency rather than enhancement in antiisch
40 ic biological assays, displaying interesting vasorelaxant properties in rat aorta by mediating nitric
41 r designing drugs to counter the noxious and vasorelaxant properties of general anesthetics and may p
42 the hypothesis that the cardioprotective and vasorelaxant properties of K(ATP) openers follow distinc
43 tioxidant, anti-inflammatory, antitumor, and vasorelaxant properties, but possible antiarrhythmic eff
44 ike rosemary, are efficacious KCNQ-dependent vasorelaxants, quantified by myography in rat mesenteric
45  In conclusion, in cirrhotic rat livers, the vasorelaxant response to NTG is impaired owing to both a
46  normal livers, NTG and SNAP induced similar vasorelaxant responses (P =.44).
47 epressed L-arginine (10(-4) mol/L)-dependent vasorelaxant responses in O rings to those of Y.
48 l dysfunction as evidenced by blunted aortic vasorelaxant responses to acetylcholine (ACh) and calciu
49 splay pronounced hypertension with deficient vasorelaxant responses to acetylcholine.
50                                          The vasorelaxant responses to anandamide have now been exami
51             Cirrhotic livers exhibited lower vasorelaxant responses, compared with normal livers, to
52 idine alkaloid aloperine is a KCNQ-dependent vasorelaxant that potently and isoform-selectively activ