ライフサイエンスコーパス: ventral horn

1 nal cord (dorsal horn, intermediate zone and ventral horn).

2 ation, and inferior olive), and spinal cord (ventral horn).

3 ly motor neurons around the periphery of the ventral horn.

4 ally coupled to motor networks in the spinal ventral horn.

5 re highly concentrated in motoneurons of the ventral horn.

6 tor column, and possible interneurons in the ventral horn.

7 e deep laminae of the dorsal horn and in the ventral horn.

8 rsal horn was significantly stiffer than the ventral horn.

9 ting muscle stretch receptors project to the ventral horn.

10 the dorsal commissure, and areas deep in the ventral horn.

11 in motor neurons from adult rat spinal cord ventral horn.

12 ionic neurons (SPNs) and interneurons of the ventral horn.

13 intermediate area, and motor neurons in the ventral horn.

14 terneurons remained scattered throughout the ventral horn.

15 the dorsal horn and motor neurons within the ventral horn.

16 ns in intermediate gray matter and in medial ventral horn.

17 cation of Renshaw cells in lamina VII of the ventral horn.

18 LI was present in the ipsilateral dorsal and ventral horn.

19 nd V of the spinal cord and do not enter the ventral horn.

20 horn is three-fold greater than in the adult ventral horn.

21 somata (motor neurons) were situated in the ventral horn.

22 mid dorsal horn (laminae II-V) and the lower ventral horn.

23 w labeled neurons were seen in the dorsal or ventral horn.

24 ed into the deeper laminae and as far as the ventral horn.

25 ry Ia afferent synapses from the spinal cord ventral horn.

26 READD expression throughout the mid-cervical ventral horn.

27 spine density on alpha-motor neurons in the ventral horn.

28 of the spinal cord, but is it denser in the ventral horn.

29 amatergic neurons that project to the spinal ventral horn.

30 n the region of the central canal and in the ventral horn.

31 activity extending into the deep dorsal and ventral horn.

32 deep dorsal horn and a 96% reduction in the ventral horn.

33 in the intermediolateral cell column and the ventral horn.

34 e, the intermediolateral cell column and the ventral horn.

35 in ipsilateral (iVH) and contralateral (cVH) ventral horns.

36 ith involvement of dorsal, intermediate, and ventral horns.

37 ity occurring between ipsilateral dorsal and ventral horns.

38 , OFQ was observed throughout the dorsal and ventral horns.

39 s which project to dorsal, intermediate, and ventral horns.

40 as also observed in contralateral dorsal and ventral horns.

41 sprouting of 5-hydroxytryptamine fibres into ventral horns.

42 e spinal cord gray matter, preferentially to ventral horns.

43 YT2(+) cells were observed in the dorsal and ventral horns.

44 aller interneurons throughout the dorsal and ventral horns.

45 nociceptive axons throughout dorsal horn and ventral horns.

46 Ventral horn 5-HT2C-IR labeling included the dorsomedial

47 In the ventral horn, 91% of boutons presynaptic to the afferent

48 -NF immunoreactivity was observed within the ventral horn alpha-motor neurons.

49 averaged C5-C7 GMV of the spinal cord dorsal/ventral horns among 3 female cohorts: controls (CON, n =

50 eus, spinal trigeminal nucleus, dorsal horn, ventral horn and central canal region were also immunore

51 ) was confirmed immunohistochemically in ALS ventral horn and corticospinal tracts.

52 y are located in distinctive clusters in the ventral horn and deep dorsal horn.

53 erve exerts a disfacilitatory effect on both ventral horn and hypoglossal motoneurons and that this d

54 utonomic motor functions and centered in the ventral horn and intermediate zone; b) a bilateral subsy

55 with a subpopulation of motor neurons in the ventral horn and neurons in Clarke's nucleus.

56 canal, in the lateral spinal nucleus, in the ventral horn and occasionally in lamina II and III.

57 ons presynaptic to afferent terminals in the ventral horn and the deep layers of the dorsal horn.

58 he avoidance of CGRP-positive axons from the ventral horn and the elaboration of the afferent arbors

59 ng occurred mainly in the medial part of the ventral horn and the lateral part of the intermediate zo

60 t the entire dorsal horn, extending into the ventral horn and the white matter of the lateral funicul

61 CI, numbers of GLT1-expressing astrocytes in ventral horn and total intraspinal GLT1 protein expressi

62 COX-1 and COX-2 in the rat spinal dorsal and ventral horns and in the dorsal root ganglia.

63 borize extensively throughout the dorsal and ventral horns and that the overall territory that the DL

64 es only sparse innervation to the dorsal and ventral horns and to the cervical and lumbosacral levels

65 These include loss of lower (ventral horn) and upper motor neurons (corticospinal mot

66 ral region, in the lateral and ventrolateral ventral horn, and around the central canal.

67 on's correlations were 0.43 +/- 0.17 between ventral horns, and 0.48 +/- 0.16 between dorsal horns.

68 of TrkC(+) proprioceptive afferents into the ventral horn are also impaired.

69 nimal models in which afferent inputs in the ventral horn are dramatically reduced (ER81(-/-) knockou

70 Labeled terminals were seen in the ventral horn as early as embryonic day 15 (E15), the beg

71 -endorphin labeled fibers and neurons in the ventral horn as well as fibers in the lateral funiculus

72 nB2 expression was dramatically increased in ventral horn astrocytes.

73 like compounds were located primarily in the ventral horn, astrocytes that were labeled for morphine-

74 observed in spinal gray matter including the ventral horn at and below the level of the lesion, indic

75 ked by microstimulation in the ventrolateral ventral horn, but not at the other locations.

76 presumptive phrenic motoneurons of the C(4) ventral horn, but not in neighbouring astrocytes or micr

77 nd peptidergic fibers in the cervical spinal ventral horn by postnatal days 7 and 12 respectively.

78 lifespan ( approximately 30%) and increases ventral horn cell number, consistent with its ability to

79 on in the number and cross-sectional area of ventral horn cells, gross motor function improvement and

80 vity in laminae I/II, V/VI, the SPN, and the ventral horn compared to rats that withdrew systemically

81 eta-estradiol decreased neuronal loss in the ventral horn, decreased reactive astrogliosis, decreased

82 (14-17/section) in the intermediate gray and ventral horn (dorsal lamina VIII, medial VII extending i

83 eral, and intersegmental correlations in the ventral horns, dorsal horns, and central spinal cord gra

84 ase, gliosis increased and EAAT2 loss in the ventral horn exceeded 90%, suggesting a role for this pr

85 of the presumed motor axon terminals in the ventral horn exhibit P2X7-IR; in contrast, almost all la

86 as to determine if motoneurons in the spinal ventral horn express the muscarinic m2 acetylcholine rec

87 ide was detected in increased amounts in the ventral horn following the stimulus.

88 AV8)-Gfa2 vector to rat cervical spinal cord ventral horn for targeting focal astrocyte GLT1 overexpr

89 by retrogradely tracing inputs to the spinal ventral horn from the medulla, ablating these medullary

90 ents), we observed differences in dorsal and ventral horn GMVs, with less GMV in FMOs vs. controls.

91 spinal cord and were especially dense in the ventral horn, IML and medial gray.

92 of hNSCs once grafted into the lumbar spinal ventral horn in presymptomatic immunosuppressed SOD1(G93

93 r intraspinal injection targeting the lumbar ventral horn in rodents.

94 comitantly within the spinal deep dorsal and ventral horn in situ after experimentally induced neurop

95 part of the medullary reticular nucleus, the ventral horn in the spinal cord of both rats and mice, a

96 as proprioceptive axon projection toward the ventral horn in the spinal cord.

97 spinal cord, notably in motor neurons of the ventral horn, in dorsal root ganglia, and in sympathetic

98 c nucleus, dorsal grey commissure and in the ventral horn including the dorsolateral nucleus which in

99 ory presynaptic terminals in the spinal cord ventral horn, including cholinergic C-terminals and moto

100 ction) in contralateral lamina I compared to ventral horn injections.

101 In this study of ventral horn interneurones in a thick slice preparation

102 lamina VIII and other intermediate zone and ventral horn interneurones.

103 hT-immunoreactive terminals contacting other ventral horn interneurones.

104 es (Trachemys scripta elegans), we show that ventral horn interneurons in mid-thoracic spinal segment

105 te binding to the NMDA receptor in the fetal ventral horn is three-fold greater than in the adult ven

106 SMA, CMAd, CMAv, and M1 all terminate in the ventral horn (lamina IX).

107 the deep dorsal horn (lamina III-V) and the ventral horn (lamina VI-IX).

108 ield potentials) and often extended into the ventral horn (laminae V-VII).

109 rgest peak was in the deep dorsal horn/upper ventral horn (laminae VI-VII), with further sites of sig

110 F1 in motoneurons, where it was required for ventral horn microglial activation and proliferation.

111 aw skin, and produced spinal cord dorsal and ventral horn microgliosis.

112 ound significant increases in the numbers of ventral horn MNs immunopositive for these enzymes in the

113 t increases in the numbers of immunopositive ventral horn MNs of G93A mice as young as 60 days of age

114 DA in the dorsal and ventral horns modulates sensory, motor, nociceptive, and

115 with significant sparing of white matter and ventral horn motoneurons at levels adjacent to the epice

116 rsolaterally located cells in the cat lumbar ventral horn), motoneurons expressed low levels of beta

117 types of amyotrophic lateral sclerosis, and ventral horn motor neurons (VMN) have been shown to die

118 aled that activated caspase-3 was present in ventral horn motor neurons at 24 hours, but not 4 hours

119 al-mediated disruption of Rac1 expression in ventral horn motor neurons can mitigate dendritic spine

120 ollowing: perikarya, dendrites, and axons of ventral horn motor neurons in adult spinal cord; perikar

121 so observed in the substantia gelatinosa and ventral horn motor neurons of the spinal cord.

122 However, retinal ganglion cells and spinal ventral horn motor neurons show very low levels of FHF2

123 ry, HNE-protein modification was detected in ventral horn motor neurons, and immunoprecipitation anal

124 nd AT(1B) mRNAs were especially prominent in ventral horn motor neurons, and in the DRG neuronal cell

125 d improved axonal and synaptic plasticity on ventral horn motor neurons.

126 d EPSP-spike (E-S) field response within the ventral horn motor nucleus disclosed a substantial enhan

127 n prominently in cortical layer V and spinal ventral horn, motor dysfunction, paralysis, and death.

128 In the ventral horn, motor neurons are coupled into clusters at

129 as tumor necrosis factor immunoreactivity in ventral horn motorneurons, suggesting that NCX 1015 redu

130 ions restricted mainly to the upper cervical ventral horn (n=5), there were many lumbosacral CTB-posi

131 hough rhythmic behaviour of mammalian spinal ventral horn networks has been extensively studied littl

132 ur results suggest that glycine receptors on ventral horn neurones in the juvenile rat are heteromers

133 In cell-attached patches from ventral horn neurones, 1 mM glycine elicited clusters of

134 3.3-IR in terminals and somatic membranes in ventral horn neurones, but not motoneurones.

135 estricted labeling, mainly confined to large ventral horn neurons and ependymal cells.

136 t GluR2 is present in synapses of dorsal and ventral horn neurons and that the percentage of labeled

137 The onset of expression of PV in ventral horn neurons coincides with later developmental

138 contrast, proprioceptive-related neurons and ventral horn neurons divided evenly.

139 A few ventral horn neurons that were not motoneurons were also

140 In addition, many ventral horn neurons were now immunoreactive as well as

141 n cross-sectional area of the somas of those ventral horn neurons which are likely to correspond to t

142 e spinal cord, again being observed in large ventral horn neurons, but also in smaller interneurons t

143 xons make glutamatergic synapses onto spinal ventral horn neurons.

144 ion of reticulospinal axons were recorded in ventral horn neurons.

145 ial dorsal horn, and FLI was not observed in ventral horn neurons.

146 to the provisional classification of turtle ventral-horn neurons on the basis of electrophysiology a

147 Human ventral horns obtained from ALS and age-matched normal s

148 ere recorded extracellularly in the thoracic ventral horn of anaesthetized, paralysed cats.

149 the rVRG, many BDA-labeled terminals in the ventral horn of cervical spinal cord (C4-C5) were immuno

150 l using an optical fractionator probe in the ventral horn of different regions of the cord and compar

151 egulation of 5-HT(2) receptors in the lumbar ventral horn of lesioned rats with and without transplan

152 ese areas include alpha motor neurons in the ventral horn of spinal cord and neurons in hypoglossal,

153 r performance and motor neuron counts in the ventral horn of spinal cords in a transgenic mouse model

154 is labeled large presumed motoneurons in the ventral horn of T12-L4, and smaller presumed interneuron

155 nlargement of the spinal cord, targeting the ventral horn of the gray matter.

156 ervical cord and in laminae I and II and the ventral horn of the lumbar cord.

157 ates with higher motor neuron density in the ventral horn of the lumbar spinal cord in G93A mice.

158 NS and enhanced loss of motor neurons in the ventral horn of the lumbar spinal cord.

159 ic populations of labeled motoneurons in the ventral horn of the lumbar spinal cord.

160 lasticity is the die-back in the spinal cord ventral horn of the projections of proprioceptive axons

161 was detected throughout the dorsal and upper ventral horn of the rat.

162 r neuron degeneration and axonal loss in the ventral horn of the spinal cord and hypoglossal nucleus

163 llapsin-1 is expressed in high levels in the ventral horn of the spinal cord and in ventricular strip

164 d to NTN and GDNF are located, including the ventral horn of the spinal cord and the compacta region

165 th highest neuroectodermal expression in the ventral horn of the spinal cord at two restricted locati

166 ized as a neuronal nucleus in the developing ventral horn of the spinal cord called the lateral motor

167 ss of the EAAT2 glutamate transporter in the ventral horn of the spinal cord coincided with gliosis,

168 acidic protein (GFAP)-positive cells in the ventral horn of the spinal cord in both ALS transgenic m

169 motorneurons, which settle into pools in the ventral horn of the spinal cord in positions that mirror

170 and a pronounced loss of motoneurons in the ventral horn of the spinal cord without the presence of

171 In the ventral horn of the spinal cord, p38 was present in moto

172 nuclei, and a subset of interneurons in the ventral horn of the spinal cord.

173 neurons were detected in the dorsal and the ventral horn of the spinal cord.

174 seen throughout the CNS, most notably in the ventral horn of the spinal cord.

175 natomical density of Ia projections into the ventral horn of the spinal cord.

176 nd visceromotor cranial nerve nuclei and the ventral horn of the spinal cord.

177 er in the lateral DLN/Onuf's position in the ventral horn of the spinal cord; these motoneurons inner

178 l cochlear nucleus, raphe magnus, and in the ventral horn of thoracic spinal cord.

179 lysosomes of motor neuron cell bodies in the ventral horn of WT mice by 3 mo of age.

180 carboxylase (GAD)(67) in both the dorsal and ventral horns of L5-L7.

181 PCR of RNA from laser capture microdissected ventral horns of normal and wobbler mice reveals a large

182 eurons, reached their highest density in the ventral horns of the cervical and lumbosacral enlargemen

183 lood flow (BF) indices were decreased in the ventral horns of the GM (BV: - 20.1%, p = 0.0009; BF: -

184 and to motor neurons and interneurons in the ventral horns of the spinal cord.

185 icosities are seen near large neurons in the ventral horn (presumed motoneurons).

186 ediate region (laminae V, VI and VII) and to ventral horn region (laminae VIII and IX).

187 t Par-4 is localized to motor neurons in the ventral horn region.

188 intermediate region and possibly also in the ventral horn region.

189 phin A(1-8) was found in both the dorsal and ventral horn regions of both sides of the spinal cord.

190 put to segmental circuits with oligosynaptic ventral horn responses, as a measure of CST-evoked segme

191 e analog of P7C3, known as P7C3A20, protects ventral horn spinal cord motor neurons from cell death i

192 lusters displayed similar characteristics on ventral horn spinal neurons.

193 l cord and throughout adulthood, even though ventral horn synapses have twice the total copy numbers,

194 orsal horn glomerular terminals and in large ventral horn synapses receiving axoaxonic contacts.

195 profiles of dorsal horn synapses, but not in ventral horn synapses.

196 o drive neuronal DREADD expression in the C4 ventral horns, targeting phrenic motoneurons.

197 Within the ventral horn, the alpha1 and alpha3 isoforms were mutual

198 the inserted T13 nerve regenerated into the ventral horn, the intermediate zone, and dorsal horn bas

199 ng was present in the superficial dorsal and ventral horns, the mediolateral and central canal region

200 jected horseradish peroxidase (HRP) into the ventral horn unilaterally in a rostral or caudal segment

201 sic fibroblast growth factor (FGF2) protects ventral horn (VH) neurons from death after experimental

202 educing ephrinB2 in the cervical spinal cord ventral horn via viral-mediated shRNA delivery reduced m

203 The size of cell somas in the ventral horn was also measured using light microscopy an

204 ting to the dorsal horn and avoidance of the ventral horn was observed in isolated dorsal and ventral

205 Those in the ventral horn were identified as alpha motor neurons usin

206 ons in neocortex, brainstem, and spinal cord ventral horn were positive for terminal deoxynucleotidyl

207 171 MRF neurons that projected to the C5-C6 ventral horn were studied; they had a conduction velocit

208 nal nucleus and some cells of the dorsal and ventral horns were Gly-ir.

209 (up to 600 microV), but also occurred in the ventral horn where they were sometimes preceded by group

210 ns were located in the intermediate area and ventral horn, whereas 50% of nonaffected neurons were lo

211 ield potentials in the intermediate zone and ventral horn, which is where T13 axons terminated.

212 diate zone, and the dorsal two-thirds of the ventral horn, while contralateral labeling occurred main

213 We compared release in the ventral horn with that in the hypoglossal nucleus to det

214 widespread loss of NR2A from both dorsal and ventral horns with losses of 55% and 78%, respectively,