ライフサイエンスコーパス: vesicular transport

1 sed as an intervention after reinitiation of vesicular transport.

2 o rhabdomere membranes via a Rab11-dependent vesicular transport.

3 livered to the lumen of the Golgi complex by vesicular transport.

4 transition (EMT), epigenetic regulation and vesicular transport.

5 rocesses, including endocytosis, repair, and vesicular transport.

6 llular processes, from muscle contraction to vesicular transport.

7 g stimulates synaptic delivery of PSD-95 via vesicular transport.

8 in and dynein function collectively to drive vesicular transport.

9 the endoplasmic reticulum (ER) by retrograde vesicular transport.

10 the endoplasmic reticulum (ER) by retrograde vesicular transport.

11 onal cells that is thought to be involved in vesicular transport.

12 surface to the endoplasmic reticulum (ER) by vesicular transport.

13 n and Htt-associated protein-1 to facilitate vesicular transport.

14 of ARF-bound GDP with GTP to regulate Golgi vesicular transport.

15 nal COPI-, COPII-, and microtubule-dependent vesicular transport.

16 ed by bacterial pathogens to manipulate host vesicular transport.

17 table signs of neurodegeneration or abnormal vesicular transport.

18 ng X-chromosome-linked genes associated with vesicular transport.

19 processes such as chromosome segregation and vesicular transport.

20 ectors that mediate all the known aspects of vesicular transport.

21 for peptide precursors as sorting signals in vesicular transport.

22 nsible for most retrograde microtubule-based vesicular transport.

23 ts apical actin placement and RAB-8-mediated vesicular transport.

24 also facilitate late-endosome-to-trans-Golgi vesicular transport.

25 n membranes, enabling the protein to undergo vesicular transport.

26 CteG might function by subverting host cell vesicular transport.

27 cytoskeleton reorganization, and protein and vesicular transport.

28 tor generation, and cytokine release through vesicular transport.

29 ope and the release of IL-12 but not IL-4 by vesicular transport.

30 M130, a Golgi-associated protein involved in vesicular transport.

31 h a model whereby PLD2 plays a role in Golgi vesicular transport.

32 d by homology to yeast Sec34p, implicated in vesicular transport.

33 regulates a cis-Golgi step in intracellular vesicular transport.

34 -containing protein implicated in regulating vesicular transport.

35 nctions of Rab25 and Rab11a in postendocytic vesicular transport.

36 legans research has provided to the field of vesicular transport.

37 mbrane t-SNARE proteins are also involved in vesicular transport.

38 ment to human bronchial epithelial cells and vesicular transport.

39 pathway, and 3) degradation does not require vesicular transport.

40 hocyte-like cells by a process that requires vesicular transport.

41 es, Arfs and Ypt/rabs, are key regulators of vesicular transport.

42 family play a key role in the regulation of vesicular transport.

43 e Golgi apparatus and may have a function in vesicular transport.

44 mmobile complexes on microtubules that limit vesicular transport.

45 med are carried through the Golgi network by vesicular transport.

46 he apoplast) via transporters, channels, and vesicular transport.

47 metabolism of APP by altering its endocytic vesicular transport.

48 lgi localization of rab1a, a key mediator of vesicular transport.

49 the endoplasmic reticulum (ER) by retrograde vesicular transport.

50 broader context of clathrin-dependent plant vesicular transport.

51 es with G-proteins to regulate intracellular vesicular transport.

52 e and helps to promote the directionality of vesicular transport.

53 erentiation/survival, T-cell activation, and vesicular transport.

54 tions to uncovering the mechanisms governing vesicular transport.

55 al phenotypes consistent with a reduction in vesicular transport activity and neurosecretion.

56 reticulum remains functionally connected by vesicular transport after its fragmentation in cells exp

57 Microtubule depolymerization disrupted vesicular transport along microtubules and caused the ac

58 Antibodies to Htt inhibited vesicular transport along microtubules, suggesting that

59 nnate immunity, cytoskeletal remodeling, and vesicular transport also exhibited differential expressi

60 , cardinal Nef functions affecting host cell vesicular transport and actin dynamics were fully preser

61 ransferase activity, have a critical role in vesicular transport and activate a phospholipase D (PLD)

62 rotein tyrosine kinase, but independent from vesicular transport and chloride channels.

63 rganization and retromer- and ESCRT-mediated vesicular transport and degradation of essential raft pr

64 For applications such as the study of vesicular transport and drug delivery, there is a pressi

65 y, GMIP-down-regulated cells showed impaired vesicular transport and exocytosis, while inhibition of

66 with the Rab27a effector JFC1 and modulates vesicular transport and exocytosis.

67 genes encoding proteins associated with ATP vesicular transport and fusion, including vesicle-associ

68 ) translocation, ER-to-Golgi trafficking and vesicular transport and fusion.

69 cal functions including signal transduction, vesicular transport and maintenance of cellular architec

70 single particles and they cluster during the vesicular transport and maturation.

71 s likely to function in clathrin-independent vesicular transport and membrane fusion events necessary

72 s play central roles in synaptic plasticity, vesicular transport and mitochondrial function.

73 smic dynein and its activator dynactin drive vesicular transport and mitotic spindle organization.

74 rfamily and are recognized as key players in vesicular transport and organelle dynamics in eukaryotic

75 ized as critical components in intracellular vesicular transport and phospholipase D activation.

76 terol itself as well as proteins involved in vesicular transport and protein glycosylation and degrad

77 cell type-restricted role for LIS1 in large vesicular transport and provide the first quantitative s

78 lly neuronal differentiation, axonal growth, vesicular transport and release, and ionic conductance.

79 ablishes a newly identified role for Bves in vesicular transport and reveals a novel, broadly applied

80 with VAMP3, a SNARE protein that facilitates vesicular transport and specifically recycles transferri

81 ontextual fear-conditioning and identify the vesicular transport and synaptogenesis pathways as the m

82 idence for an alternative novel mechanism of vesicular transport and vacuolar sequestration of anthoc

83 gulation, ubiquitination, dephosphorylation, vesicular transport, and cell adhesion.

84 lecule transport, cell wall maintenance, and vesicular transport, and include many open reading frame

85 -modifying enzymes, molecular motor-mediated vesicular transport, and intracellular signaling by loca

86 any proteins that regulate the cytoskeleton, vesicular transport, and physiology of the narrow canals

87 angers and cytoskeletal elements involved in vesicular transport, and raises the possibility that abn

88 l parasites, supports long, multidirectional vesicular transport, and regulates transport, density an

89 es, proteins of the translational machinery, vesicular transport, and signaling.

90 es: one transcellular, via caveolae-mediated vesicular transport, and the other paracellular, through

91 functions, and the other with transcription, vesicular transport, and ubiquitination.

92 S-acylation/deacylation cycles and vesicular transport are critical for an adequate subcell

93 We show that anterograde or retrograde vesicular transports are asymptotic behaviors of a much

94 AB23, encoding a small GTPase that regulates vesicular transport, are present in the majority of case

95 Syntaxins are thought to function during vesicular transport as receptors on the target membrane

96 ts, those interfering with the intracellular vesicular transport as well as inhibition of the fusion

97 ch functions in endosome-to-Golgi retrograde vesicular transport, as a critical player in sphingolipi

98 G (AnkG), a cytoskeletal protein involved in vesicular transport, as a novel aldosterone-induced prot

99 emodeling is important for the regulation of vesicular transport associated with exocytosis, but a di

100 a mediator of endoplasmic reticulum to Golgi vesicular transport, at T75 to be regulated by TAK1 in v

101 c leaflet is essential for +ALPS binding and vesicular transport between the EE and the TGN.

102 -kD hydrophilic protein that is required for vesicular transport between the ER and Golgi complex.

103 eins to the TGN requires continual cycles of vesicular transport between the TGN and endosomal compar

104 ily of clathrin adaptor proteins involved in vesicular transport between the trans-Golgi network and

105 feldin A-induced endoplasmic reticulum/Golgi vesicular transport block.

106 nesin motor proteins are used for long-range vesicular transport but microtubules do not extend into

107 ng agents colchicine or nocodazole abrogated vesicular transport but not the flow of the nanotube sur

108 Coat proteins have a central role in vesicular transport by binding to cargoes for their sort

109 Rab GTPases play an essential role in vesicular transport by coordinating the movement of vari

110 ment network presents numerous challenges to vesicular transport by teams of myosin Va (MyoVa) molecu

111 Rab proteins and their effectors facilitate vesicular transport by tethering donor vesicles to their

112 Rab GTPases and their effectors facilitate vesicular transport by tethering donor vesicles to their

113 cant structural and mechanistic parallels to vesicular transport by the clathrin/AP2 system.

114 This vesicular transport can be reconstituted by using three

115 ation, protein folding, quality control, and vesicular transport can be well predicted by the single

116 complexity by which a single small GTPase in vesicular transport can coordinate its multiple steps to

117 ed that LTP-mediated lipid trafficking, like vesicular transport, can be subject to tight Ca(2+)regul

118 In the secretory pathway, budding of vesicular transport carriers from the trans-Golgi networ

119 GN) is the sorting of proteins into distinct vesicular transport carriers that mediate secretion and

120 mediated biogenesis of cargo-enriched tubulo-vesicular transport carriers.

121 embrane asymmetry and play critical roles in vesicular transport, cell polarity, signal transduction,

122 associated with multiple functions including vesicular transport, cell signaling, oxidation state, cy

123 , general bud site selection, cell polarity, vesicular transport, cell wall synthesis, protein modifi

124 veolae and is implicated in the processes of vesicular transport, cholesterol balance, transformation

125 ells, these vesicles coalesce to form tubulo-vesicular transport complexes (TCs), which shuttle anter

126 bladders, which was blocked by inhibitors of vesicular transport, connexin hemichannels, ABC protein

127 observe both direct delivery of tubular and vesicular transport containers (TCs) from sorting endoso

128 These pathways commonly depend on vesicular transport controlled by Rabs, small GTPases in

129 amphetamine treatment and suggested that non-vesicular transport could be the main mechanism establis

130 e leads to cellular abnormalities, including vesicular transport defects and increased endoplasmic re

131 Other over-responders are annotated to have vesicular transport defects, traceable to lipid defects

132 ole in sustaining a microtubule track during vesicular transport deserves investigation.

133 Vesicular transport enables the export of large molecule

134 A twofold increase in vesicular transport enhances the vesicular capacity for

135 Precise regulation of these two aspects of vesicular transport ensures efficient cargo transfer whi

136 Vesicular transport events appear to be facilitated by t

137 We now describe serum-regulated upstream vesicular transport events leading to centrosomal Rab8 a

138 in inflammation/immunity, uptake/transport, vesicular transport/exocytosis, apoptosis/cellular stres

139 atter homologue, p20, has a putative role in vesicular transport from ER to Golgi complex.

140 Thus, TBC1D14- and Rab11-dependent vesicular transport from REs contributes to and regulate

141 rapidly, in a process that does not require vesicular transport from the ER.

142 tates the efficient initiation of retrograde vesicular transport from the neurite tip.

143 nomeric clathrin-adaptor protein involved in vesicular transport from the TGN.

144 major player in clathrin coat formation for vesicular transport from the trans-Golgi to the endocyti

145 e important functions beyond their classical vesicular transport functions, including nutrient sensin

146 inflammation, neuronal injury, autophagy and vesicular transport genes are observed in PD with and wi

147 SNAP, other proteins apparently unrelated to vesicular transport (glyceraldehyde-3-phosphate dehydrog

148 Rab GTPases, key regulators of vesicular transport, hydrolyze GTP very slowly unless as

149 m used by Legionella pneumophila to modulate vesicular transport in both protozoan and mammalian host

150 animals that are characterized by defects in vesicular transport in cell bodies of motor neurons, axo

151 ar membrane fusion, an essential process for vesicular transport in cells.

152 ar membrane fusion, an essential process for vesicular transport in cells.

153 on, cargo protein sorting, and regulation of vesicular transport in eukaryotic cells.

154 The discovery of vesicular transport in fungi opens many new avenues for

155 volution of the Rab family in particular and vesicular transport in general, and may be used to predi

156 membrane with only a limited contribution of vesicular transport in recycling endosomes.

157 ization; GSLs are required for intracellular vesicular transport in resorption-active intestine.

158 itted a careful evaluation of the role(s) of vesicular transport in transmitter-specific behaviors.

159 SEC24 is essential for vesicular transport in vivo because depletion of Sec24p

160 member of a gene family believed to regulate vesicular transport in yeast, but without known function

161 function, specifically in the regulation of vesicular transport, in specific regions of the develope

162 ormation rather than the situation with most vesicular transport, in which the forming vesicle concen

163 l cAMP (DBcAMP), stimulators of transcytotic vesicular transport, increased the biliary recovery of D

164 The vesicular transport inhibitor brefeldin A inhibited CCE

165 AP complexes play roles in the formation of vesicular transport intermediates and the selection of c

166 ent studies have demonstrated that polarized vesicular transport involving Rab8 and its guanine nucle

167 Vesicular transport is a general mechanism that governs

168 This dataset yields insights into how vesicular transport is adapted to the specialized functi

169 contributed to a basic understanding of how vesicular transport is initiated.

170 Non-vesicular transport is mediated by the interaction of me

171 ar pathway and suggest that ER to peroxisome vesicular transport is not required to provide lipids fo

172 The mechanism of vesicular transport is not well understood, and little i

173 The role of the class VI myosins in vesicular transport is particularly intriguing because t

174 Thus, although vesicular transport is the limiting factor determining q

175 Microtubule-based vesicular transport is well documented in epithelial cel

176 GTPases, the key organizers of intracellular vesicular transport, is essential for their function.

177 s a distinct myosin function, presumably the vesicular transport, is involved in elongation of the ro

178 d with calcein AM under conditions that slow vesicular transport (low temperature and stationary grow

179 These include the induction of the RAB vesicular transport machinery and a general down-regulat

180 ce locus, rhg1, identified expression of the vesicular transport machinery component, alpha soluble N

181 The experiments indicate a role for the vesicular transport machinery during infection of soybea

182 bits the expression of key components of the vesicular transport machinery, and down-regulates Glutam

183 express components of the insulin-sensitive vesicular transport machinery, namely, VAMP2, syntaxin-4

184 assays, we identified the components of the vesicular transport machinery, the GEF Rabin8 and the GT

185 of a defense response by the activity of the vesicular transport machinery.

186 toreceptors as part of the cell signaling or vesicular transport machinery.

187 A vesicular transport mechanism was confirmed by colocaliz

188 ole/lysosome by a constitutive non-classical vesicular transport mechanism, the cytoplasm to vacuole

189 vels in nerve terminals are 5-7 mm, and that vesicular transport mechanisms are not saturated under b

190 IL-16 also elicited brefeldin A-inhibitable, vesicular transport-mediated release of preformed IL-4,

191 eukin (IL)-16, eotaxin, and RANTES stimulate vesicular transport-mediated release of preformed, granu

192 IL-16 induced the rapid vesicular transport-mediated release of RANTES.

193 r, we also uncovered evidence for selective, vesicular transport-mediated turnover of a single INM pr

194 of fundamental cellular processes, including vesicular transport, mitosis, and cell migration.

195 A core prediction of the vesicular transport model is that COPI vesicles are resp

196 perspective on the facilitated diffusion and vesicular transport models to account for the emerging c

197 Membrane budding is a key step in vesicular transport, multivesicular body biogenesis, and

198 utophagy and lysosomal catabolism reflecting vesicular transport obstruction and defective lysosomal

199 1 transport activity was normal, as shown by vesicular transport of [(3)H]17beta-estradiol-17-beta-(D

200 lar degradation of Abeta and facilitated the vesicular transport of Abeta to lysosomes.

201 phoid follicle-associated epithelium conduct vesicular transport of antigens from the mucosal surface

202 g demonstrated that PKC inhibitors inhibited vesicular transport of apoE to the plasma membrane.

203 osomal disturbance) or alter the polarity of vesicular transport of autophagosomes on microtubules, c

204 Here we show that AbetaOs reduce vesicular transport of brain-derived neurotrophic factor

205 ved particular attention for its role in the vesicular transport of cationic transmitters as well as

206 the sphingolipid sphingomyelin requires non-vesicular transport of ceramide from the endoplasmic ret

207 uggests that ATP11B contributes to secretory vesicular transport of cisplatin from Golgi to plasma me

208 dmilling and selective recycling by internal vesicular transport of cortex-bound transmembrane protei

209 on of the microtubule cytoskeleton disturbed vesicular transport of DHE but not its enrichment in the

210 ically imaged, in pairwise combinations, the vesicular transport of fluorescently tagged components o

211 lvement of vesicular glutamate transports in vesicular transport of glutamate.

212 ansgenic expression of Rab4, which regulates vesicular transport of heptahelical receptors to plasma

213 between HRas and PI3K, locally reinforced by vesicular transport of HRas to the axonal growth cone.

214 findings are challenging long-held models of vesicular transport of large matrix proteins, such as pr

215 ane traffic at the Golgi, is involved in the vesicular transport of LAT to the immune synapse.

216 model of retrograde signaling whereby rapid vesicular transport of ligand-receptor complex from the

217 their membrane composition by regulating the vesicular transport of membrane-bound sterol regulatory

218 Indeed, the vesicular transport of most classical transmitters invol

219 ytosis, but the proteins responsible for the vesicular transport of neurotransmitters are still being

220 rable evidence supports a model in which the vesicular transport of neurotrophin-Trk complexes transm

221 xits of interendothelial spaces; and (v) the vesicular transport of orosomucoid is strongly inhibited

222 In contrast to vesicular transport of other cargo via glycolipids, Py p

223 of different cells types where it regulates vesicular transport of proteins and membrane components.

224 osome (MVB) plays a key role in coordinating vesicular transport of proteins between the Golgi comple

225 in complexes (COPI and COPII), which mediate vesicular transport of proteins to and from the ER.

226 Whereas vesicular transport of Tf and efflux of DHE from the ERC

227 PKD1 influences cell migration by directing vesicular transport of the alphavbeta3 integrin heterodi

228 Although vesicular transport of the H-Ras protein from the Golgi

229 tions as a carrier for the sequestration and vesicular transport of the potent eosinophil granule cat

230 ic vesicles, but the protein responsible for vesicular transport of the principal excitatory transmit

231 However, vesicular transport of the principal excitatory transmit

232 Silencing HTT reduces vesicular transport of TrkB in striatal neurons.

233 of Arf-bound GDP with GTP for initiation of vesicular transport or activation of specific enzymes th

234 F1, relevant for COPI/Arf1-mediated cellular vesicular transport, participates in the replication cyc

235 the targeting of many proteins that use the vesicular transport pathway and thus favors its successf

236 to define a late-endosome-to-plasma-membrane vesicular transport pathway important in viral assembly.

237 The SNARE-mediated vesicular transport pathway plays major roles in synapti

238 evealed that iRGD coadministration induced a vesicular transport pathway that carried Au-labeled sili

239 alpha-COP binds to SMN, linking the COPI vesicular transport pathway to SMA.

240 ctions of both NPC1 and Ptc involve a common vesicular transport pathway.

241 t least partly through the inhibition of the vesicular transport pathway.

242 osphoinositides play key regulatory roles in vesicular transport pathways in eukaryotic cells.

243 we now rule out an essential role for known vesicular transport pathways in transporting the major y

244 Coat complexes sort protein cargoes into vesicular transport pathways.

245 f GTPases, acting as essential regulators of vesicular transport pathways.

246 Unlike the situation in conventional vesicular transport, precursor Ape1, along with its rece

247 st the induction of an autophagocytosis-like vesicular transport process during ectomycorrhizal inter

248 indings indicate that, if Rab24 functions in vesicular transport processes, it may operate through a

249 vesicular membranes necessary for long range vesicular transport processes.

250 cover an unexpected molecular link between a vesicular transport protein and a syndrome of autoimmuni

251 We have identified Rab8, a vesicular transport protein associated with trans-Golgi

252 A subset of the Arf1-COPI vesicular transport proteins also regulated droplet morp

253 Molecular analysis of vesicular transport proteins has revealed important info

254 Vesicular transport proteins package classical neurotran

255 ly by inhibiting KRAS proximity to the SNARE vesicular transport proteins SNAP23, SNAP29, and VAMP3.

256 n the current paradigm of cargo selection in vesicular transport, proteins to be sorted to other orga

257 on continued polarized secretion, suggesting vesicular transport provides a positive feedback signal

258 rane-association domains disrupts retrograde vesicular transport, recapitulating the BPAG1 null pheno

259 However, vesicular transport requires PSD-95 palmitoylation to at

260 These data suggest that deregulation of vesicular transport results in reduced capacitative calc

261 er 60 distinct Rab GTPases regulate specific vesicular transport steps in the mammalian central vacuo

262 rstanding of membrane-localized processes in vesicular transport, such as membrane budding and fissio

263 ikely by compromising the development of the vesicular transport system for ACh preventing it from ac

264 ossess a pharmacopoeia of (1) the eukaryotic vesicular transport system, (2) immunity, and (3) previo

265 d PS2 partially co-localized to sites of the vesicular transport system.

266 iew we discuss the function of intracellular vesicular transport systems in reovirus entry, trafficki

267 uitination, transcription, and flagellar and vesicular transport systems.

268 to monensin, tamoxifen decreased the rate of vesicular transport though the recycling and secretory p

269 d that Pyk2 may be involved in regulation of vesicular transport through its interaction with Pap.

270 0 years ago, such basic questions as whether vesicular transport through the Golgi occurs in an anter

271 increase in tumor cGMP levels and increased vesicular transport through tumor capillaries, and could

272 t known for regulating membrane dynamics and vesicular transport; thus, we performed photobleaching e

273 reformed in human eosinophils for release by vesicular transport to contribute to immune responses.

274 Recent findings indicate that fungi use vesicular transport to deliver substances across their c

275 atory protein that links MICAL-L1.EHD1-based vesicular transport to dynein motors.

276 AnkX protein prevented microtubule-dependent vesicular transport to interfere with fusion of the L. p

277 and redistribute proteins after delivery by vesicular transport to neural cell plasma membranes.

278 for diverse cellular processes ranging from vesicular transport to nuclear envelope breakdown to mit

279 nt for their interdependent cellular role in vesicular transport to primary cilia.

280 We have previously proposed a model of vesicular transport to provide stabilized ACC in chicken

281 experimental evidence for the components of vesicular transport to supply ACC in a vertebrate model

282 reveal that BBS may be caused by defects in vesicular transport to the cilium.

283 ceptors, and quantitatively leave the ER via vesicular transport to the Golgi.

284 s were found to remain largely intact during vesicular transport to the nucleus.

285 s cycles of endocytosis, solubilization, and vesicular transport to the PM.

286 tic trafficking from the plasma membrane, or vesicular transport to the vacuole, has a smaller effect

287 Incoming human papillomavirus (HPV) utilize vesicular transport to traffic from the plasma membrane

288 s revealed that, in this zone, alteration of vesicular transport together with cytoskeleton dynamics

289 Myosin Va (MyoVa) mediates F-actin-based vesicular transport toward the plasma membrane and is fo

290 An unusually low rate of vesicular transport (transcytosis) has been identified a

291 ons and extremely low rates of transcellular vesicular transport (transcytosis).

292 icles are key components of the machinery of vesicular transport used by eukaryotic cells.

293 ve endoderm, suggesting that a deficiency in vesicular transport via early endosomes underlies the mu

294 Vesicular transport was not disrupted by filipin providi

295 cular mechanism of the EFA6/Arf6 function in vesicular transport, we searched for new EFA6 partners.

296 ilarly, normal sphingolipid biosynthesis and vesicular transport were required for optimal growth upo

297 GTP-binding proteins known for their role in vesicular transport, where they nucleate the assembly of

298 ing between eukaryotic compartments requires vesicular transport, wherein tethering provides the firs

299 wn to regulate early stages of intracellular vesicular transport, without proteasomal involvement.

300 cerevisiae that is temperature sensitive for vesicular transport, YopM failed to accumulate in the nu