ライフサイエンスコーパス: virus protein

1 gether can account for nearly half the total virus protein.

2 AT1 colocalizes with the corresponding Nipah virus protein.

3 nts performed with vectors encoding a single virus protein.

4 re of M156R, the first structure of a myxoma virus protein.

5 rst report of STAT activation by a DNA tumor virus protein.

6 utant uracil-N-glycosylase or Herpes Simplex Virus protein.

7 endogenous processing of de novo synthesized virus protein.

8 d chromatin association of NS1, an influenza virus protein.

9 the functions of this essential influenza A virus protein.

10 NA) surface glycoprotein and other influenza virus proteins.

11 disordered residues for a set of influenza A virus proteins.

12 on detecting natural selection on influenza virus proteins.

13 d localized to rafts in the absence of other virus proteins.

14 ponse of CD8+ cells to both HIV and vaccinia virus proteins.

15 2D(b)-restricted peptides from two influenza virus proteins.

16 vaccine expressed multiple immunodeficiency virus proteins.

17 opment of the HDV genomic RNA by hepatitis B virus proteins.

18 lk culture PBMC against nonstructural dengue virus proteins.

19 e VSV G protein over either of the influenza virus proteins.

20 nthesized or exogenously delivered influenza virus proteins.

21 n which RB has been inactivated by DNA tumor virus proteins.

22 ies that target conserved internal influenza virus proteins.

23 458K, F981L, S982L) as well as in five other virus proteins.

24 eta sheet components in DNA varicella-zoster virus proteins.

25 cription factor NF-kappaB, responds to Ebola virus proteins.

26 nce for the phosphoglycosylation of vaccinia virus proteins.

27 a virus protein or combinations of influenza virus proteins.

28 of the most abundantly SUMOylated influenza virus proteins.

29 eptide pools representing distinct influenza virus proteins.

30 sequence and biochemical information for the virus proteins.

31 e network perturbations caused by DNA tumour virus proteins.

32 included an apparent smaller variant of the virus protein 1 (VP1) and a small proportion of a cleave

33 mposed primarily of the major capsid protein virus protein 1 (VP1), and pentameric arrangement of VP1

34 chimeric protein, formed by fusing vaccinia virus protein 14K (A27) to the CS of Plasmodium yoelii,

35 vant-like effect of the immunogenic vaccinia virus protein 14K.

36 Interestingly, virus protein 24 (VP24) and nucleoprotein (NP) appear to

37 was to understand the possible role of a FMD virus protein 3A, in causing disease in cattle.

38 ell response to rotavirus and is directed to virus protein 6 (VP6).

39 xpanded from single B cells responding to RV virus protein 6 or virus protein 7.

40 B cells responding to RV virus protein 6 or virus protein 7.

41 Using Protein C Epitope -Tobacco Etch Virus-Protein A Epitope (PTP)-tagged Tb11.01.4590, addit

42 utoinhibitory domain and African swine fever virus protein A238L] block the Ca(2+)-dependent reductio

43 The vaccinia virus proteins A30 and G7 are known to play essential ro

44 is also assembled downstream of the Vaccinia virus protein A36 and the phagocytic Fc-gamma receptor F

45 Vaccinia virus protein A49 inhibits NF-kappaB activation by molec

46 Subsequently, as the virus proteins accumulate, secondary cleavages of eIF4G

47 on of replication products was detected, but virus protein accumulation was reduced two- to threefold

48 studied their roles in plaquing efficiency, virus protein accumulation, infectious-center titer, and

49 In this study, we examined whether Ebola virus proteins affect BST2-mediated induction of NF-kapp

50 SV) vector, to deliver and express influenza virus proteins against which vaccinated animals develop

51 Unlike other DNA virus proteins, AL1 does not contain the pRb binding con

52 Virus protein analysis by various techniques, including

53 phosphorylation mediated by a herpes simplex virus protein and inhibits viral replication.

54 The direct interaction between a respiratory virus protein and the pneumococcus resulting in increase

55 ites are relatively close, are controlled by virus proteins and a diverse range of host proteins.

56 e host factors that associate with influenza virus proteins and affect viral replication.

57 s, numerous interactions between hepatitis C virus proteins and cellular components have been identif

58 controls CD4 T-cell reactivity to influenza virus proteins and how the influenza virus-specific memo

59 he E1- and E4-deleted vector expresses fewer virus proteins and induces less apoptosis, leading to bl

60 ism induced by vaccination against six Ebola virus proteins and provide additional evidence that cyto

61 n target more conserved regions of influenza virus proteins and recognize a broader array of influenz

62 ze the spatio-temporal distribution of Ebola virus proteins and RNA during virus replication.

63 entation, virus-host interaction merges with virus-protein and host-protein networks, introducing red

64 ction of Nature's equivalents (e.g. enzymes, viruses, proteins and DNA).

65 ze SARS-CoV-2 G4s, inhibit the expression of virus protein, and reduce the SARS-CoV-2 RNA copies and

66 ting the complex interaction between lipids, virus proteins, and buffer conditions in membrane fusion

67 F formation, colocalization with associating virus proteins, and characterization of virus replicatio

68 tiple responses targeting internal influenza virus proteins, and found that each T(FH) cell state was

69 viruses expressing all individual influenza virus proteins, and so it is unlikely that the stimulati

70 that recognize the other agent at the whole-virus, protein, and peptide levels, consistent with bidi

71 protective antibody development is to direct virus protein antigens specifically to dendritic cells,

72 well as to cytomegalovirus and Epstein-Barr virus protein antigens, were also regulated by either or

73 The chicken anemia virus protein Apoptin induces apoptosis in the absence o

74 The chicken anemia virus protein Apoptin selectively induces apoptosis in t

75 IMPORTANCE Interactions among virus proteins are critical for assembly and egress of v

76 such that only a subset of so-called latent virus proteins are expressed in virus infected tumours a

77 orly understood and it is not known if other virus proteins are required.

78 a 775-residue multifunctional herpes simplex virus protein associated with numerous functions related

79 ctivated NF-kappaB in concert with the Ebola virus proteins at least as effectively as wild-type BST2

80 igate the amino acid sequence of the Bombali virus proteins at the SDPs that discriminate between hum

81 d a novel role for B1 in inhibiting vaccinia virus protein B12, which otherwise impedes an early even

82 ince SFs have been defined for all influenza virus proteins based on known structural, functional, an

83 The crystal structure of Epstein-Barr virus protein BCRF1, an analog of cellular interleukin-1

84 dies provided evidence that E10R, a vaccinia virus protein belonging to the ERV1/ALR family, has a re

85 e production and identify a new host protein-virus protein binding interface that could become a usef

86 A method to identify mutations of virus proteins by using protein mass mapping is describe

87 om other poxviruses, but not in the vaccinia virus proteins C2 or F3.

88 A virus protein called Tat plays a dual role in HIV infect

89 are independently targeted by a single mumps virus protein, called V, that assembles STAT-directed ub

90 n-protein interactions of many host cell and virus proteins can change dynamically throughout the cou

91 Single-amino-acid mutations in Sindbis virus proteins can convert clinically silent encephaliti

92 ese findings provide evidence that mammalian virus proteins can inhibit RNA silencing, implicating th

93 2 protein, in the absence of other influenza virus proteins, can induce neuraminidase-specific antibo

94 Furthermore, we demonstrate that other virus proteins cannot substitute for this lack of functi

95 nment that favor the translation of late (L) virus proteins: cellular mRNAs are degraded, immediate e

96 f a wide variety of analytes, including DNA, viruses, proteins, chemical vapors, and pesticides.

97 particles (VLPs) composed of an icosahedral virus protein coat encapsulating a functionalized spheri

98 acks icosahedral order characteristic of the virus protein coating (capsid).

99 ng known residues at the interface of a host-virus protein complex with a partially solved structure.

100 ecificity; the tomato and bean golden mosaic virus proteins complexed with each other.

101 Mutagenesis of the vaccinia virus protein confirmed that changing the electrostatic

102 zing antibodies targeting internal influenza virus proteins could be useful for the design of broadly

103 The cowpox virus protein CPXV012 deprives the endoplasmic reticulum

104 By contrast, overexpression of the cowpox virus protein CrmA blocked apoptosis induced by engageme

105 The cowpox virus protein CrmA, a known inhibitor of ICE family prot

106 that NS4B regulates the function of host or virus proteins directly involved in HCV production.

107 In many instances, archaeal virus proteins display very low levels of sequence homol

108 ing of the role of VP40 and additional Ebola virus proteins during budding.

109 trating direct interactions between host and virus proteins during infection is a major goal and chal

110 s probably involve conformational changes of virus proteins during their association with the vector.

111 g the functional interactions of three Nipah virus proteins during viral assembly and particularly on

112 ping peptide library based on structural TBE virus proteins E and C revealed that CD4(+) T cells conc

113 tion of pocket proteins with human papilloma virus protein E7 partially, but not completely, restored

114 of the interaction between the Epstein-Barr virus protein EBNA2 with BTD and explore the extent to w

115 parable to that produced by the Epstein-Barr virus protein EBNA2, a well-characterized, potent transa

116 Epstein-Barr virus proteins EBNA3A, EBNA3B and EBNA3C control hundred

117 ansferase p300 and an essential Epstein-Barr virus protein, EBNA3C, involved in regulation of viral a

118 Activation of NF-kappaB by the Ebola virus proteins either alone or together with BST2 requir

119 tation has been attributed to the absence of virus proteins either facilitating movement or counterac

120 Importantly, the virus protein encoded by E184L is highly immunogenic, ma

121 a serological marker, we identified that the virus protein encoded by the MGF110-5L-6L gene induced a

122 ous studies indicated that exposure to Ebola virus proteins expressed from packaged Venezuelan equine

123 ly), plays important roles in the control of virus protein expression and that this knowledge could b

124 ight the possibility of increasing influenza virus protein expression and the need for a delicate bal

125 Virus protein expression evaluated by indirect immunoflu

126 ll activation while simultaneously enhancing virus protein expression.

127 ring effects of copyback DIs on nondefective virus protein expression.

128 wever for positive sense single-stranded RNA viruses, protein expression is often controlled via seco

129 We now demonstrate that the vaccinia virus protein F11, which localizes to the plasma membran

130 ipitation assays, we found that the vaccinia virus protein F14 associates with NF-kappaB co-activator

131 ipitation assays, we found that the vaccinia virus protein F14 associates with NF-kB co-activator CRE

132 uch viral prosurvival protein is the fowlpox virus protein FPV039, which is a potent apoptosis inhibi

133 The structure of the human virus protein free in solution consists of an eight-stra

134 ing cell culture systems to fully understand virus protein functions.

135 eoside triphosphatase; 20-kDa protein (p20); virus protein, genome linked (VPg); proteinase (Pro); po

136 hibition of RNA interference (RNAi) by plant virus proteins has been shown to enhance viral replicati

137 the eukaryotic homologue of a herpes simplex virus protein, has the crystallin motif of heat shock pr

138 the past 2 decades, several novel influenza virus proteins have been identified that modulate viral

139 ed similarities to interactions of other DNA virus proteins (human papillomavirus type 16 E6 and E7,

140 za A virus NS1 protein or the herpes simplex virus protein ICP34.5, rescues growth of influenza delNS

141 GADD34 has homology with the Herpes Simplex Virus protein, ICP34.5, which overcomes the protein synt

142 otein processing, we used the herpes simplex virus protein ICP47 to block peptide transport by TAP1/2

143 In contrast to the cytosolic herpes simplex virus protein ICP47, US6 interacts with TAP inside the e

144 ing and disruption of an essential influenza virus protein in the absence of genetic manipulation of

145 this mutant confirmed the presence of mutant virus protein in the transfected BHK cell lysate.

146 r epithelial infection 24 h after challenge, virus protein in the vaginal lumen 3 days after challeng

147 ficantly increased the concentration of shed virus protein in the vaginal lumen after challenge.

148 epithelium infected, concentrations of shed virus protein in the vaginal lumen, and illness scores,

149 ins with the membrane bilayer and with other virus proteins in an attempt to understand the role this

150 CTL, MC57 and JawsII process the same set of virus proteins in quantitatively different ways.

151 The role of individual virus proteins in the induction of these cytokine respon

152 pears to be brokered by additional influenza virus proteins, in this case M1.

153 id rafts without a requirement for any other virus protein, including the SH and G envelope proteins.

154 s allowed one to identify all 10 influenza A virus proteins, including low-abundance proteins like th

155 s dephosphorylation of multiple cellular and virus proteins, including the cellular ceramide (Cer) tr

156 However, unlike the small DNA tumor virus proteins, individual HCMV IE proteins target diffe

157 this method to probe the release of specific virus proteins initiated by thermal stimulation, mimicki

158 a network of >3400 virus-host and >150 virus-virus protein interactions, providing insights into func

159 result of loss of VF formation or important virus protein interactions.

160 The stacked disk aggregate of tobacco mosaic virus protein is an intriguing object due to its high de

161 despite the enhanced activity of the variola virus protein, its cofactor activity in the factor I-med

162 xpression the of the endogenous Epstein-Barr virus protein kinase (EBV PK, encoded by the BGLF4 gene)

163 This protein kinase, designated RVPK (rabies virus protein kinase), phosphorylates P protein (36 kDa)

164 ICP0 is a multifunctional herpes simplex virus protein known primarily as a promiscuous transacti

165 L2 is one of several vaccinia virus proteins known to be necessary for formation of cr

166 Recent evidence that a herpes virus protein lacking a classical secretory signal seque

167 of two transgenic rats expressing the simian virus protein large T antigen under the control of the a

168 However, how virus protein-lipid interactions contribute to the viral

169 The Epstein-Barr virus protein LMP1 is essential for transformation of re

170 Here, we used the Epstein-Barr virus protein LMP2A as a constitutively active BCR surro

171 s utilize caspases during replication to aid virus protein maturation, progeny release, or both.

172 ent viral vector vaccine coding for internal virus proteins may be able to protect against HIV type 1

173 Molluscum contagiosum virus proteins MC159 and MC160 and the equine herpesviru

174 al (CVIA057, NCT03300050) using an influenza virus protein microarray (IVPM).

175 th vaccinia virus, as determined by vaccinia virus protein microarray.

176 HMI_Pred which relies on the rationale that virus proteins mimic host proteins.

177 Here, we show that a vaccinia virus protein mimics the transactivation domain of the p

178 Here, we show that a vaccinia virus protein mimics the transactivation domain of the p

179 D4 and CD8 T-cell responses to several Ebola virus proteins, most notably the viral nucleoprotein.

180 Other substrates such as the Rous sarcoma virus protein NC are phosphorylated by gamma-PAK followi

181 of M1.IMPORTANCE The complement of influenza virus proteins necessary for the budding of progeny viri

182 We further show that the influenza A virus protein NS1 counteracts the anti-viral activity of

183 the structural characteristics of influenza virus protein NS2 (NEP), which interacts with the nuclea

184 as ribosomes (proteins and RNA) or enveloped viruses (proteins, nucleic acids and lipids).

185 physical characterization of nanoparticles, viruses, proteins, nucleic acids, and other macromolecul

186 res coordinated binding of multiple host and virus proteins onto specific regions of the virus genome

187 ine candidates consist of a single influenza virus protein or combinations of influenza virus protein

188 there are no atomic structures for any CCHF virus proteins or for any Nairovirus proteins.

189 erns of molecular level modifications in the virus proteins or genome that lead to the inhibition of

190 ation studies, single-cell RNA-Seq, and host-virus proteins or protein/RNA interactome.

191 propose a model in which certain influenza A virus proteins (or protein domains) exist as highly plas

192 vide evidence that the 2009 H1N1 influenza A virus protein PA-X plays a role in virus replication and

193 iated with the recently identified influenza virus protein PB1-F2 has been largely defined using mode

194 The influenza A virus protein PB1-F2 has been linked to the pathogenesis

195 c studies of DPRs derived from the influenza virus protein PB2 showed that they poison replication of

196 pothesis that each isoform of herpes simplex virus proteins performs a specific function that may be

197 investigated the functions of two essential virus proteins, pp150 and pUL96, and determined the impa

198 This could restrict virus protein production and growth.

199 We tested virus protein production, virion composition and infecti

200 The systematic identification of human-virus protein-protein interactions (PPIs) is a critical

201 increasingly important role to predict human-virus protein-protein interactions (PPIs).

202 we identified several well-established host-virus protein-protein interactions, and confirmed that P

203 The virus life cycle depends on host-virus protein-protein interactions, which often involve

204 BRLF1 promoter in the context of the latent virus, protein-protein interactions, or both.

205 Five conserved vaccinia virus proteins, referred to as Viral Membrane Assembly P

206 isease, we examined if sequence diversity of virus proteins reflects evasion of HLA presentation.

207 at mRNA vaccines encoding internal influenza virus proteins represent a promising strategy to induce

208 vity, implying that K4L is the only vaccinia virus protein required for the nicking-joining enzymatic

209 81), in the absence of any other influenza B virus proteins resulted in the inhibition of IRF-3 nucle

210 th experiments using cowpea chlorotic mottle virus proteins: RNAs with more complex structure yield m

211 heat shock protein 70, stabilizes bluetongue virus proteins, safeguarding them from proteasomal degra

212 or PLZF, as well as ZID, GAGA and a vaccinia virus protein, SalF17R, also interact with varying affin

213 Hepatitis C virus proteins serve dual functions in replication and i

214 these A protein-dependent differences in the virus protein shell are not seen using crystallography,

215 play a role in the global arrangement of the virus protein shell.

216 unit vaccine composed of protective vaccinia virus proteins should avoid the complications arising fr

217 Four virus proteins similar to two human macrophage inflammat

218 For both primary and TCLA virus proteins, soluble stabilized trimers generated neu

219 Stabilization of virus protein structure and nucleic acid integrity is ch

220 association between some pairs of influenza virus proteins, such as M2 and NP, appears to be brokere

221 4(+) T cell responses to particular vaccinia virus proteins suggesting that CD4(+) T cell help is pre

222 export, which strongly inhibits influenza A virus protein synthesis and reduces cytokine production.

223 Finally, we showed that influenza virus protein synthesis and viral mRNA levels decrease i

224 uring infection and also delayed and reduced virus protein synthesis from replicating RNA.

225 d is defective in the inhibition of host and virus protein synthesis showed an altered phosphorylatio

226 duced antiviral activity against influenza A virus protein synthesis was reduced 5- to 20-fold by sup

227 xhibits a general delay in the initiation of virus protein synthesis, but this is not due to a glycop

228 induction by measles virus (MV) and inhibits virus protein synthesis.

229 was found to bind to human immunodeficiency virus protein Tat, and this binding required the nucleol

230 ously proposed for the human T-cell leukemia virus protein Tax are discussed.

231 Among several vaccinia virus proteins tested, the H4L subunit, unique to the vi

232 VP39 is a bifunctional vaccinia virus protein that acts as both an mRNA cap-specific RNA

233 intestinal epithelial cells of M3, a herpes virus protein that binds and inhibits multiple chemokine

234 When the gene for ICP47, a herpes simplex virus protein that blocks the translocation of peptides

235 itutively expressed, phosphorylated vaccinia virus protein that has been implicated in viral DNA repl

236 PA-X is a recently identified influenza virus protein that is composed of the PA N-terminal 191

237 CAP activity is inhibited by CrmA, a cowpox virus protein that prevents host cell apoptosis.

238 This study provides the first evidence for a virus protein that targets IL-18BP and further validates

239 omplex, regulated process coordinated by two virus proteins that are conserved among the herpesviruse

240 The virus proteins that mediate this centripetal transport a

241 The identification of host and virus proteins that modulate the induction of immunologi

242 ntified mutations in the PB1, NP, HA, and NA virus proteins that were highly conserved in the poultry

243 evel of production of an essential influenza virus protein, the M2 ion channel protein.

244 that 10% were orthologs of Chilo iridescent virus proteins, the highest correspondence with any viru

245 roteins predicted that altering the vaccinia virus protein to contain the amino acids present in the

246 raging the fusogenic property of the Measles virus proteins to screen a human ORFeome expression libr

247 The ability of DNA tumor virus proteins to trigger apoptosis in mammalian cells i

248 agents comprise broad classes of pathogens (virus, protein toxins, bacterial spores, vegetative cell

249 ell and facilitates the classical cascade of virus protein translation.

250 the channel-forming trans-membrane domain of virus protein "u" (Vpu) of HIV-1 was determined by NMR s

251 The herpes simplex virus protein UL25 attaches to the external vertices of

252 ing the glycoprotein (GP) and matrix protein virus protein (VP)40, administered 1-3 d before Ebola vi

253 infection of human cells, the herpes simplex virus protein VP16 associates with the endogenous cell-p

254 the estrogen receptor or the herpes simplex virus protein VP16 generates transcriptional regulators

255 ith activation domains of the herpes simplex virus protein VP16 or the tomato Myb-like activator THM1

256 The activation domain from the herpes virus protein VP16 restored the ability of the bacteria

257 The herpes simplex virus protein VP22 is a major phosphoprotein of infected

258 We used this system to investigate the Ebola virus protein VP24, showing that, contrary to previous r

259 Vaccinia virus protein VP8 is a 25 kDa product of the L4R gene an

260 ry-like (VFL) structures and colocalize with virus proteins was characterized.

261 re translated sequences of 5 major influenza virus proteins, we assessed the specificity of CD4 T cel

262 ning glycosylation to the study of influenza virus proteins, we can better understand the effect that

263 ions of poxvirus, herpesvirus, and influenza virus proteins, we propose a model for viral fitness and

264 titutions in this region of the Rous sarcoma virus protein were lethal due to a severe deficiency in

265 murine CD8(+) T-cell responses to six Ebola virus proteins were examined.

266 ccine vectors expressing conserved influenza virus proteins were given intranasally.

267 ain phage gene products and eukaryotic dsDNA virus proteins were noted, in particular, the primase/he

268 Bulk cultures revealed that a number of virus proteins were recognized in CTL assays.

269 When plasmids expressing individual Ebola virus proteins were transfected into Madin Darby canine

270 wn to be required for modifying the vaccinia virus protein, which is synthesized and assembled into v

271 he S component and one with a herpes simplex virus protein with an apparent Mr of 43,000.

272 smallpox protein would result in a vaccinia virus protein with increased complement regulatory activ

273 by electron microscopy and immunolabeling of virus proteins with antibodies conjugated to gold beads.

274 V) replication depends on the interaction of virus proteins with host factors.

275 s several direct target genes of hepatitis B virus protein X (HBx), a viral co-factor.

276 ious studies have shown that the hepatitis B virus protein, X, activates all three classes of RNA pol

277 membrane cargo protein vesicular stomatitis virus protein-yellow fluorescent protein revealed that v